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Nfam1 NFAT activating protein with ITAM motif 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362966, updated on 4-Jan-2025

Summary

Official Symbol
Nfam1provided by RGD
Official Full Name
NFAT activating protein with ITAM motif 1provided by RGD
Primary source
RGD:1308316
See related
EnsemblRapid:ENSRNOG00000022975 AllianceGenome:RGD:1308316
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308316
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in B cell differentiation; B cell receptor signaling pathway; and calcineurin-NFAT signaling cascade. Predicted to act upstream of or within regulation of B cell differentiation. Predicted to be located in cell surface and membrane. Predicted to be active in membrane raft. Orthologous to human NFAM1 (NFAT activating protein with ITAM motif 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 87.7), Lung (RPKM 40.1) and 9 other tissues See more
Orthologs
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Genomic context

See Nfam1 in Genome Data Viewer
Location:
7q34
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (116019383..116055628, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (114139318..114175395, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (123856718..123893790, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 2 Neighboring gene transcription factor 20 Neighboring gene uncharacterized LOC134479801 Neighboring gene uncharacterized LOC103692952 Neighboring gene serine hydrolase-like 2 Neighboring gene ribosomal RNA processing 7 homolog A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cell surface  
located_in membrane  
is_active_in membrane raft  
located_in membrane raft  

General protein information

Preferred Names
NFAT activation molecule 1
Names
Nfat activating molecule with ITAM motif 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    116019383..116055628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242142.5XP_006242204.1  NFAT activation molecule 1 isoform X3

    See identical proteins and their annotated locations for XP_006242204.1

    UniProtKB/TrEMBL
    A0A8I6ALW3, A6HT79
    Related
    ENSRNOP00000096487.2, ENSRNOT00000106015.2
  2. XM_039080308.2XP_038936236.1  NFAT activation molecule 1 isoform X6

  3. XM_039080306.2XP_038936234.1  NFAT activation molecule 1 isoform X2

    UniProtKB/TrEMBL
    A6HT79
  4. XM_006242140.5XP_006242202.1  NFAT activation molecule 1 isoform X1

    See identical proteins and their annotated locations for XP_006242202.1

    UniProtKB/TrEMBL
    F1M0C3
    Related
    ENSRNOP00000030943.5, ENSRNOT00000037681.7
  5. XM_063264693.1XP_063120763.1  NFAT activation molecule 1 isoform X5

  6. XM_039080307.2XP_038936235.1  NFAT activation molecule 1 isoform X4

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