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Slco1a6 solute carrier organic anion transporter family, member 1a6 [ Mus musculus (house mouse) ]

Gene ID: 28254, updated on 4-Jan-2025

Summary

Official Symbol
Slco1a6provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 1a6provided by MGI
Primary source
MGI:MGI:1351906
See related
Ensembl:ENSMUSG00000079262 AllianceGenome:MGI:1351906
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oatp5; Oatp-5; Slc21a13; 4930422F19Rik
Summary
Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Acts upstream of or within several processes, including bile acid metabolic process; cholesterol homeostasis; and triglyceride homeostasis. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in brain ventricle and choroid plexus; metanephros; and telencephalon ventricular layer. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward kidney adult (RPKM 11.4) See more
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Genomic context

See Slco1a6 in Genome Data Viewer
Location:
6 G2; 6 73.42 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142031487..142131903, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142085761..142186177, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30843 Neighboring gene solute carrier organic anion transporter family, member 1a1 Neighboring gene solute carrier organic anion transporter family, member 1a8 Neighboring gene STARR-seq mESC enhancer starr_17699 Neighboring gene STARR-seq mESC enhancer starr_17700 Neighboring gene predicted gene, 18159 Neighboring gene STARR-seq mESC enhancer starr_17701 Neighboring gene predicted gene, 53313 Neighboring gene solute carrier organic anion transporter family, member 1a5 Neighboring gene STARR-seq mESC enhancer starr_17703 Neighboring gene islet amyloid polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in basal plasma membrane  
is_active_in basolateral plasma membrane  
located_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
solute carrier organic anion transporter family member 1A6
Names
kidney-specific organic anion-transporting polypeptide 5
organic anion-transporting polypeptide
solute carrier family (organic anion transporter) member 13
solute carrier family 21 (organic anion transporter), member 13
solute carrier family 21 member 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001381930.1NP_001368859.1  solute carrier organic anion transporter family member 1A6

    Status: VALIDATED

    Source sequence(s)
    AC134836, AK142587
    UniProtKB/Swiss-Prot
    Q3UQC6, Q99J94, Q9CUP7
    UniProtKB/TrEMBL
    Q6IR20
    Conserved Domains (1) summary
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter
  2. NM_023718.3NP_076207.1  solute carrier organic anion transporter family member 1A6

    See identical proteins and their annotated locations for NP_076207.1

    Status: VALIDATED

    Source sequence(s)
    AK142587, AK143970
    Consensus CDS
    CCDS39693.1
    UniProtKB/Swiss-Prot
    Q3UQC6, Q99J94, Q9CUP7
    UniProtKB/TrEMBL
    Q6IR20
    Related
    ENSMUSP00000107458.4, ENSMUST00000111827.4
    Conserved Domains (1) summary
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    142031487..142131903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506965.3XP_006507028.1  solute carrier organic anion transporter family member 1A6 isoform X1

    See identical proteins and their annotated locations for XP_006507028.1

    UniProtKB/Swiss-Prot
    Q3UQC6, Q99J94, Q9CUP7
    UniProtKB/TrEMBL
    Q6IR20
    Conserved Domains (1) summary
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter
  2. XM_011241587.2XP_011239889.1  solute carrier organic anion transporter family member 1A6 isoform X1

    See identical proteins and their annotated locations for XP_011239889.1

    UniProtKB/Swiss-Prot
    Q3UQC6, Q99J94, Q9CUP7
    UniProtKB/TrEMBL
    Q6IR20
    Conserved Domains (1) summary
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter
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