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KRTAP10-10 keratin associated protein 10-10 [ Homo sapiens (human) ]

Gene ID: 353333, updated on 4-Jan-2025

Summary

Official Symbol
KRTAP10-10provided by HGNC
Official Full Name
keratin associated protein 10-10provided by HGNC
Primary source
HGNC:HGNC:22972
See related
Ensembl:ENSG00000221859 AllianceGenome:HGNC:22972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KAP10.10; KAP18.10; KRTAP18-10; KRTAP18.10
Summary
Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See KRTAP10-10 in Genome Data Viewer
Location:
21q22.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (44637356..44638455)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42997807..42998906)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46057273..46058372)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene thrombospondin type laminin G domain and EAR repeats Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46031985-46032634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46032635-46033283 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46036915-46037661 Neighboring gene keratin associated protein 10-8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46045935-46046630 Neighboring gene keratin associated protein 10-9 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46067006-46067870 Neighboring gene keratin associated protein 10-11 Neighboring gene keratin associated protein 12-4

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytosol  
located_in keratin filament  

General protein information

Preferred Names
keratin-associated protein 10-10
Names
high sulfur keratin-associated protein 10.10
keratin-associated protein 18-10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181688.3NP_859016.1  keratin-associated protein 10-10

    See identical proteins and their annotated locations for NP_859016.1

    Status: VALIDATED

    Source sequence(s)
    AJ566387, AL773602
    Consensus CDS
    CCDS33585.1
    UniProtKB/Swiss-Prot
    P60014
    Related
    ENSP00000369438.1, ENST00000380095.2
    Conserved Domains (2) summary
    pfam01500
    Location:114245
    Keratin_B2; Keratin, high sulfur B2 protein
    pfam13885
    Location:146197
    Keratin_B2_2; Keratin, high sulfur B2 protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    44637356..44638455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    42997807..42998906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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