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mediator of RNA polymerase II transcription subunit 27 [Rattus norvegicus]

NCBI Reference Sequence: NP_001100035.1

Identical Proteins FASTA Graphics 

LOCUS       NP_001100035             311 aa            linear   ROD 22-MAR-2023
DEFINITION  mediator of RNA polymerase II transcription subunit 27 [Rattus
            norvegicus].
ACCESSION   NP_001100035 XP_001076126 XP_216025
VERSION     NP_001100035.1
DBSOURCE    REFSEQ: accession NM_001106565.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 311)
  AUTHORS   Poss ZC, Ebmeier CC and Taatjes DJ.
  TITLE     The Mediator complex and transcription regulation
  JOURNAL   Crit Rev Biochem Mol Biol 48 (6), 575-608 (2013)
   PUBMED   24088064
  REMARK    Review article
REFERENCE   2  (residues 1 to 311)
  AUTHORS   Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL,
            Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J
            and Young RA.
  TITLE     Mediator and cohesin connect gene expression and chromatin
            architecture
  JOURNAL   Nature 467 (7314), 430-435 (2010)
   PUBMED   20720539
  REMARK    Erratum:[Nature. 2011 Apr 14;472(7342):247]
REFERENCE   3  (residues 1 to 311)
  AUTHORS   Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC and Tora L.
  TITLE     ATAC and Mediator coactivators form a stable complex and regulate a
            set of non-coding RNA genes
  JOURNAL   EMBO Rep 11 (7), 541-547 (2010)
   PUBMED   20508642
REFERENCE   4  (residues 1 to 311)
  AUTHORS   Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R,
            Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW
            and Conaway RC.
  TITLE     Mammalian mediator subunit mMED8 is an Elongin BC-interacting
            protein that can assemble with Cul2 and Rbx1 to reconstitute a
            ubiquitin ligase
  JOURNAL   Proc Natl Acad Sci U S A 99 (16), 10353-10358 (2002)
   PUBMED   12149480
REFERENCE   5  (residues 1 to 311)
  AUTHORS   Malik S, Gu W, Wu W, Qin J and Roeder RG.
  TITLE     The USA-derived transcriptional coactivator PC2 is a submodule of
            TRAP/SMCC and acts synergistically with other PCs
  JOURNAL   Mol Cell 5 (4), 753-760 (2000)
   PUBMED   10882111
REFERENCE   6  (residues 1 to 311)
  AUTHORS   Ryu S, Zhou S, Ladurner AG and Tjian R.
  TITLE     The transcriptional cofactor complex CRSP is required for activity
            of the enhancer-binding protein Sp1
  JOURNAL   Nature 397 (6718), 446-450 (1999)
   PUBMED   9989412
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001076126.1, XP_216025.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167032.1, EV772276.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     Protein         1..311
                     /product="mediator of RNA polymerase II transcription
                     subunit 27"
                     /calculated_mol_wt=35158
     Region          228..309
                     /region_name="Med27"
                     /note="Mediator complex subunit 27; pfam11571"
                     /db_xref="CDD:463298"
     CDS             1..311
                     /gene="Med27"
                     /gene_synonym="RGD1564993"
                     /coded_by="NM_001106565.1:48..983"
                     /db_xref="GeneID:296612"
                     /db_xref="RGD:1564993"
ORIGIN      
        1 madvlsvgvn leafsqaisa iqalrssvsr vfdclkdgmr nketlegrek afiahfqdnl
       61 hsvnrdlnel erlsnlvgkp senhplhnsg llsldpvqdk tplysqllqa ykwsnklqyh
      121 aglasgllnq qslkrsanqm gvsakrrpka qpttlvlppq yvddvisrid rmfpemsihl
      181 srpngtsavl lvtlgkvlkv ivvmrslfid rtivkgynes vytedgkldi wskssyqvfq
      241 kvtdhattal lhyqlpqmpd vvvrsfmtwl rsyiklfqap cqrcgkflqd glpptwrdfr
      301 tleafhdtcr q
//
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