LOCUS NP_001000020 330 aa linear ROD 24-OCT-2024
DEFINITION olfactory receptor Olr1454 [Rattus norvegicus].
ACCESSION NP_001000020 XP_220495
VERSION NP_001000020.1
DBSOURCE REFSEQ: accession NM_001000020.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (residues 1 to 330)
AUTHORS Gibbs,R.A., Weinstock,G.M., Metzker,M.L., Muzny,D.M.,
Sodergren,E.J., Scherer,S., Scott,G., Steffen,D., Worley,K.C.,
Burch,P.E., Okwuonu,G., Hines,S., Lewis,L., DeRamo,C., Delgado,O.,
Dugan-Rocha,S., Miner,G., Morgan,M., Hawes,A., Gill,R., Celera,
Holt,R.A., Adams,M.D., Amanatides,P.G., Baden-Tillson,H.,
Barnstead,M., Chin,S., Evans,C.A., Ferriera,S., Fosler,C.,
Glodek,A., Gu,Z., Jennings,D., Kraft,C.L., Nguyen,T.,
Pfannkoch,C.M., Sitter,C., Sutton,G.G., Venter,J.C., Woodage,T.,
Smith,D., Lee,H.M., Gustafson,E., Cahill,P., Kana,A.,
Doucette-Stamm,L., Weinstock,K., Fechtel,K., Weiss,R.B., Dunn,D.M.,
Green,E.D., Blakesley,R.W., Bouffard,G.G., De Jong,P.J.,
Osoegawa,K., Zhu,B., Marra,M., Schein,J., Bosdet,I., Fjell,C.,
Jones,S., Krzywinski,M., Mathewson,C., Siddiqui,A., Wye,N.,
McPherson,J., Zhao,S., Fraser,C.M., Shetty,J., Shatsman,S.,
Geer,K., Chen,Y., Abramzon,S., Nierman,W.C., Havlak,P.H., Chen,R.,
Durbin,K.J., Simons,R., Ren,Y., Song,X.Z., Li,B., Liu,Y., Qin,X.,
Cawley,S., Worley,K.C., Cooney,A.J., D'Souza,L.M., Martin,K.,
Wu,J.Q., Gonzalez-Garay,M.L., Jackson,A.R., Kalafus,K.J.,
McLeod,M.P., Milosavljevic,A., Virk,D., Volkov,A., Wheeler,D.A.,
Zhang,Z., Bailey,J.A., Eichler,E.E., Tuzun,E., Birney,E.,
Mongin,E., Ureta-Vidal,A., Woodwark,C., Zdobnov,E., Bork,P.,
Suyama,M., Torrents,D., Alexandersson,M., Trask,B.J., Young,J.M.,
Huang,H., Wang,H., Xing,H., Daniels,S., Gietzen,D., Schmidt,J.,
Stevens,K., Vitt,U., Wingrove,J., Camara,F., Mar Alba,M.,
Abril,J.F., Guigo,R., Smit,A., Dubchak,I., Rubin,E.M., Couronne,O.,
Poliakov,A., Hubner,N., Ganten,D., Goesele,C., Hummel,O.,
Kreitler,T., Lee,Y.A., Monti,J., Schulz,H., Zimdahl,H.,
Himmelbauer,H., Lehrach,H., Jacob,H.J., Bromberg,S.,
Gullings-Handley,J., Jensen-Seaman,M.I., Kwitek,A.E., Lazar,J.,
Pasko,D., Tonellato,P.J., Twigger,S., Ponting,C.P., Duarte,J.M.,
Rice,S., Goodstadt,L., Beatson,S.A., Emes,R.D., Winter,E.E.,
Webber,C., Brandt,P., Nyakatura,G., Adetobi,M., Chiaromonte,F.,
Elnitski,L., Eswara,P., Hardison,R.C., Hou,M., Kolbe,D., Makova,K.,
Miller,W., Nekrutenko,A., Riemer,C., Schwartz,S., Taylor,J.,
Yang,S., Zhang,Y., Lindpaintner,K., Andrews,T.D., Caccamo,M.,
Clamp,M., Clarke,L., Curwen,V., Durbin,R., Eyras,E., Searle,S.M.,
Cooper,G.M., Batzoglou,S., Brudno,M., Sidow,A., Stone,E.A.,
Venter,J.C., Payseur,B.A., Bourque,G., Lopez-Otin,C., Puente,X.S.,
Chakrabarti,K., Chatterji,S., Dewey,C., Pachter,L., Bray,N.,
Yap,V.B., Caspi,A., Tesler,G., Pevzner,P.A., Haussler,D.,
Roskin,K.M., Baertsch,R., Clawson,H., Furey,T.S., Hinrichs,A.S.,
Karolchik,D., Kent,W.J., Rosenbloom,K.R., Trumbower,H.,
Weirauch,M., Cooper,D.N., Stenson,P.D., Ma,B., Brent,M.,
Arumugam,M., Shteynberg,D., Copley,R.R., Taylor,M.S., Riethman,H.,
Mudunuri,U., Peterson,J., Guyer,M., Felsenfeld,A., Old,S.,
Mockrin,S. and Collins,F.
CONSRTM Rat Genome Sequencing Project Consortium
TITLE Genome sequence of the Brown Norway rat yields insights into
mammalian evolution
JOURNAL Nature 428 (6982), 493-521 (2004)
PUBMED 15057822
COMMENT REVIEWED REFSEQ: This record has been curated by Janet Young and
Barbara Trask (FHCRC). The reference sequence was derived from
JAXUCZ010000010.1.
On Aug 30, 2004 this sequence version replaced XP_220495.1.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. [provided by RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..330
/organism="Rattus norvegicus"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="10"
/map="10q22"
Protein 1..330
/product="olfactory receptor Olr1454"
/note="olfactory receptor gene Olr1454"
/calculated_mol_wt=36094
Region 23..299
/region_name="7tmA_OR2T-like"
/note="olfactory receptor subfamily 2T and related
proteins, member of the class A family of
seven-transmembrane G protein-coupled receptors; cd15421"
/db_xref="CDD:320543"
Region 24..50
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320543"
Region 57..83
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320543"
Site order(79,82..83,95..100,102..103,106,151,153..157,193,
196..198,200..202,204..205,250,253..254,256..257,260,
266..267,269..271,274,277..278)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320543"
Region 95..125
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320543"
Region 138..159
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320543"
Region 193..223
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320543"
Region 230..260
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320543"
Region 267..292
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320543"
CDS 1..330
/gene="Olr1454"
/coded_by="NM_001000020.1:1..993"
/db_xref="GeneID:287343"
/db_xref="RGD:1333852"
ORIGIN
1 mdkgnattgf illglfdhtr ahlflfvlvl tvafnsvvgn alllllihqd rrlhtpmyfl
61 lsqlslmdmm lvstivpqma agyltgknsi saagcgfqif ffltlgggec fllaamsydr
121 yvavchplry pvliswqlcl rltlgswllg aadgamqaaa tmsfqfcsrh eidhffceap
181 vllhlacgnt safefvmyic cvlmllipfs lilasyglil tavlrmrste arkktfatcc
241 shltvvglfy gaaafsymrp asarsanhdk vvsafytivt pmlnpliysl rnsevkgslr
301 kclarcsalr skdtlvgldl agatkekgiq
//