fructose-2,6-bisphosphatase TIGAR isoform 2 [Rattus norvegicus]

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Metformin regulates the Th17/Treg balance by glycolysis with TIGAR in hepatic ischemia-reperfusion injury. [J Pharmacol Sci. 2021]
Metformin regulates the Th17/Treg balance by glycolysis with TIGAR in hepatic ischemia-reperfusion injury.
Jiang A, Du P, Liu Y, Pu J, Shi J, Zhang H. J Pharmacol Sci. 2021 May; 146(1):40-48. Epub 2021 Feb 26.
TIGAR suppresses seizures induced by kainic acid through inhibiting oxidative stress and neuronal apoptosis. [Biochem Biophys Res Commun. 2019]
TIGAR suppresses seizures induced by kainic acid through inhibiting oxidative stress and neuronal apoptosis.
Chen C, Mei Q, Wang L, Feng X, Tao X, Qiu C, Zhu J. Biochem Biophys Res Commun. 2019 Jul 30; 515(3):436-441. Epub 2019 May 31.
TIGAR impedes compression-induced intervertebral disc degeneration by suppressing nucleus pulposus cell apoptosis and autophagy. [J Cell Physiol. 2020]
TIGAR impedes compression-induced intervertebral disc degeneration by suppressing nucleus pulposus cell apoptosis and autophagy.
Li Z, Shao Z, Chen S, Huang D, Peng Y, Chen S, Ma K. J Cell Physiol. 2020 Feb; 235(2):1780-1794. Epub 2019 Jul 17.

RefSeq mRNA
See reference mRNA sequence for the Tigar gene (NM_001025064.2).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the Tigar gene.

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