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putative inactive neutral ceramidase B isoform 2 [Homo sapiens]

NCBI Reference Sequence: NP_001308889.1

Identical Proteins FASTA Graphics 

LOCUS       NP_001308889             160 aa            linear   PRI 11-FEB-2024
DEFINITION  putative inactive neutral ceramidase B isoform 2 [Homo sapiens].
ACCESSION   NP_001308889
VERSION     NP_001308889.1
DBSOURCE    REFSEQ: accession NM_001321960.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 160)
  AUTHORS   Avramopoulos,D., Wang,R., Valle,D., Fallin,M.D. and Bassett,S.S.
  TITLE     A novel gene derived from a segmental duplication shows perturbed
            expression in Alzheimer's disease
  JOURNAL   Neurogenetics 8 (2), 111-120 (2007)
   PUBMED   17334805
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI459539.1, DC404141.1, AL589794.7 and CA312157.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.275647.1,
                                           SRR1803617.493988.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2159607, SAMN03267763
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..160
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q11.23"
     Protein         1..160
                     /product="putative inactive neutral ceramidase B isoform
                     2"
                     /note="putative inactive neutral ceramidase B; ASAH2-like
                     protein; putative inactive non-lysosomal ceramidase B;
                     N-acylsphingosine amidohydrolase (non-lysosomal
                     ceramidase) 2B; putative inactive N-acylsphingosine
                     amidohydrolase 2B"
                     /calculated_mol_wt=17894
     Region          2..157
                     /region_name="Ceramidse_alk_C"
                     /note="Neutral/alkaline non-lysosomal ceramidase,
                     C-terminal; pfam17048"
                     /db_xref="CDD:465340"
     CDS             1..160
                     /gene="ASAH2B"
                     /gene_synonym="ASAH2C; ASAH2L; bA449O16.3; bA98I6.3"
                     /coded_by="NM_001321960.2:236..718"
                     /note="isoform 2 is encoded by transcript variant 5"
                     /db_xref="CCDS:CCDS81465.1"
                     /db_xref="GeneID:653308"
                     /db_xref="HGNC:HGNC:23456"
                     /db_xref="MIM:610987"
ORIGIN      
        1 mvanlsrgpe ppffkqlivp lipsivdrap kgrtfgdvlq pakpeyrvge vaevifvgan
       61 pknsvqnqth qtfltvekye atstswqivc ndaswetrfy whkgllglsn atvewhipdt
      121 aqpgiyriry fghnrkqdil kpavilsfeg tspafevvti
//
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