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NCBI Reference Sequence: NP_775440.1
Identical Proteins FASTA Graphics
LOCUS NP_775440 866 aa linear ROD 01-APR-2024 DEFINITION vomeronasal 2 receptor, 18 [Rattus norvegicus]. ACCESSION NP_775440 XP_344851 VERSION NP_775440.1 DBSOURCE REFSEQ: accession NM_173318.2 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (residues 1 to 866) AUTHORS Young,J.M. and Trask,B.J. TITLE V2R gene families degenerated in primates, dog and cow, but expanded in opossum JOURNAL Trends Genet 23 (5), 212-215 (2007) PUBMED 17382427 REFERENCE 2 (residues 1 to 866) AUTHORS Herrada,G. and Dulac,C. TITLE A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution JOURNAL Cell 90 (4), 763-773 (1997) PUBMED 9288755 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAXUCZ010000001.1. On Dec 17, 2003 this sequence version replaced XP_344851.1. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## FEATURES Location/Qualifiers source 1..866 /organism="Rattus norvegicus" /strain="BN" /db_xref="taxon:10116" /chromosome="1" /map="1q12" Protein 1..866 /product="vomeronasal 2 receptor, 18" /note="putative pheromone receptor (Go-VN4)" /calculated_mol_wt=98832 Region 50..513 /region_name="PBP1_pheromone_receptor" /note="Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily; cd06365" /db_xref="CDD:380588" Site order(79,179..180,403) /site_type="other" /note="putative ligand binding site [chemical binding]" /db_xref="CDD:380588" Site order(117,120,163,253) /site_type="other" /note="putative dimer interface [polypeptide binding]" /db_xref="CDD:380588" Region 521..574 /region_name="NCD3G" /note="Nine Cysteines Domain of family 3 GPCR; pfam07562" /db_xref="CDD:462210" Region 594..845 /region_name="7tmC_V2R_pheromone" /note="vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors; cd15283" /db_xref="CDD:320410" Region 594..619 /region_name="TM helix 1" /note="TM helix 1 [structural motif]" /db_xref="CDD:320410" Site order(597,600..601,604..605,607..608,642,646,649..650,658, 662) /site_type="other" /note="putative dimer interface [polypeptide binding]" /db_xref="CDD:320410" Region 631..652 /region_name="TM helix 2" /note="TM helix 2 [structural motif]" /db_xref="CDD:320410" Site order(651,663..664,667..668,671,751,756,759..760,763,797, 800..801,804,808,816..817,820,823,827) /site_type="other" /note="putative allosteric modulator binding site [chemical binding]" /db_xref="CDD:320410" Region 661..685 /region_name="TM helix 3" /note="TM helix 3 [structural motif]" /db_xref="CDD:320410" Region 709..725 /region_name="TM helix 4" /note="TM helix 4 [structural motif]" /db_xref="CDD:320410" Region 752..778 /region_name="TM helix 5" /note="TM helix 5 [structural motif]" /db_xref="CDD:320410" Region 786..809 /region_name="TM helix 6" /note="TM helix 6 [structural motif]" /db_xref="CDD:320410" Region 814..839 /region_name="TM helix 7" /note="TM helix 7 [structural motif]" /db_xref="CDD:320410" CDS 1..866 /gene="Vom2r18" /coded_by="NM_173318.2:126..2726" /db_xref="GeneID:286984" /db_xref="RGD:708409" ORIGIN 1 msrlragknm ltfillffll niplfvpsfi yprcfwsmkk neyqdrnlgt gcmffilavq 61 qpmekeyfsh isniqtpten qkypltlafs mneinnnpdl lpnmslaftf seyscylesh 121 hkrlfnfslk nheilpnfic tkdikcgvvl tglslvttvt lhiilnnfif qqfrqltygh 181 fhpalcdhen fphlyqmasd dtslalalvs fiihfswnwi glaisdndqg ihflsylrre 241 mekntvcfaf vniipvnmnl ymsraevyys qvmtssanvv iiygdtgntl avsfrmwdsl 301 giqrlwvtts qwdvtpfkkd ftfdngygtf gfghrhseis gfkyfvqtln pfkysdeylv 361 klewmyvnck ileynckslk ncsfnhslew lmthtfdmai iegsyeiyna vyafahalhe 421 mtlqnvdnvl lpnyeeqnyn ckmvysflsk tqftnpvgdt vnmnqrnklk eeydifynwn 481 fpqglgfkvk igifspyfpk gqqlhlsenl iewstgriqm ptsvcsadcg pgfrkvwkng 541 mpaccfdcsp cpeneisnet nvelcvqcpe dqyanqeqnh cihkarifls ydeplgmals 601 lmalclaalt vvvlgvfvkh hrtpivkann ctltyillia lifcflcplf fighpnsatc 661 ilqqitfgvv ftvaistvla ktttvilafr vtaphrmmky flvsrasnyi ipictliqii 721 vcaiwlgasp psvdidaqse hghiiiacnk gsvtafycvl gylaclafvs ftlaflsrnl 781 pvtfneaksm tfsmlvfcsv wvtflpvyhg tkgkvmvave ifstlassag mlgcifapkc 841 ytilfrpdrn slqmirekss shthil //
Whole sequence Selected region from: to:
Conserved Domains
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