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NCBI Reference Sequence: XP_005503161.1
Identical Proteins FASTA Graphics
LOCUS XP_005503161 570 aa linear VRT 24-MAY-2017 DEFINITION WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform X1 [Columba livia]. ACCESSION XP_005503161 VERSION XP_005503161.1 DBLINK BioProject: PRJNA217047 DBSOURCE REFSEQ: accession XM_005503104.3 KEYWORDS RefSeq. SOURCE Columba livia (rock pigeon) ORGANISM Columba livia Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_004973285.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process [WARNING] On May 8, 2024 this sequence was replaced by XP_005503161.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Columba livia Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..570 /organism="Columba livia" /db_xref="taxon:8932" /chromosome="Unknown" /sex="male" /tissue_type="blood" /geo_loc_name="Denmark: Vordingborg" /collection_date="13-Jun-2010" /breed="Danish Tumbler" /note="bred by Anders Christiansen, Hans Ove Christiansen, and certified by Danmarks Racedueforeninger" Protein 1..570 /product="WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform X1" /calculated_mol_wt=63846 Region 39..88 /region_name="WAP" /note="WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095" /db_xref="CDD:459672" Region 135..171 /region_name="KAZAL_FS" /note="Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104" /db_xref="CDD:238052" Region 207..301 /region_name="IgI_3_WFIKKN-like" /note="Third immunoglobulin-like domain of the human WFIKKN (WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein), and similar domains; member of the I-set of Ig superfamily (IgSF) domains; cd05765" /db_xref="CDD:409422" Region 207..210 /region_name="Ig strand A" /note="Ig strand A [structural motif]" /db_xref="CDD:409422" Region 215..218 /region_name="Ig strand A'" /note="Ig strand A' [structural motif]" /db_xref="CDD:409422" Region 223..230 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409422" Region 237..242 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409422" Region 243..245 /region_name="Ig strand C'" /note="Ig strand C' [structural motif]" /db_xref="CDD:409422" Region 247..252 /region_name="Ig strand D" /note="Ig strand D [structural motif]" /db_xref="CDD:409422" Region 260..266 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409422" Region 280..288 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409422" Region 291..301 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409422" Region 322..373 /region_name="Kunitz_WFIKKN_1-like" /note="first Kunitz domain of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing proteins; cd22605" /db_xref="CDD:438648" Site order(329..333,335..337,352,356) /site_type="other" /note="putative serine protease binding site [polypeptide binding]" /db_xref="CDD:438648" Region 380..432 /region_name="Kunitz_WFIKKN_2-like" /note="second Kunitz domain of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing proteins; cd22606" /db_xref="CDD:438649" Site order(387..391,393..395,410,414) /site_type="other" /note="putative serine protease binding site [polypeptide binding]" /db_xref="CDD:438649" Region 449..557 /region_name="NTR_WFIKKN" /note="NTR domain, WFIKKN subfamily; WFIKKN proteins contain a C-terminal NTR domain and are putative secreted proteins which may be multivalent protease inhibitors that act on serine proteases as well as metalloproteases. Human WFIKKN and a related protein...; cd03575" /db_xref="CDD:239630" Site order(472,526,533,535) /site_type="active" /note="Metzincin-binding interface [active]" /db_xref="CDD:239630" CDS 1..570 /gene="WFIKKN2" /coded_by="XM_005503104.3:31..1743" /db_xref="GeneID:102088798" ORIGIN 1 mllvlftrwm willgkssvl lllevslqgr alppirysha gicpndmnpn lwvdaqstck 61 receadlece tfekccpnvc gtkscvaary mdvkgkkgpv gmpkeatcdr fmciqqgsec 121 diwdgqpvck ckdrcekeps ftcasdglty ynkcymdaea cikgitlnvv tcryhltwpn 181 tspippetta rpttaysett vidilppalv nnpvhqsvyv getvsflcdv tgrpkpeitw 241 ekqvdgkekv imkpnhvrgn vvvtniaqlv iyntqlqdag iytctarnsg gllradfpls 301 vikgeptske asqnkthfpt declkqpdse dcgeeqtrwy ydakknncft fiygncnsnl 361 nhfetyencm ltcmngpini cnlpalqghc kayeprwayn sltkqcqsfi yggcggnenn 421 fesreaceem cpfpknthck ackprqklvt sfcksdfvil griteltedq dsghalvtve 481 eilkdekmgl kflgkeplei tllnmdwscp cpnmttvdgq liimgdvhng mavlqpdsfv 541 gtssirrvrk lrevihkktc ellkeflglh //
Whole sequence Selected region from: to:
Conserved Domains
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