Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
NCBI Reference Sequence: XP_038934831.1
Identical Proteins FASTA Graphics
LOCUS XP_038934831 1521 aa linear ROD 22-FEB-2024 DEFINITION leucine-rich repeat serine/threonine-protein kinase 2 isoform X5 [Rattus norvegicus]. ACCESSION XP_038934831 VERSION XP_038934831.1 DBLINK BioProject: PRJNA1074393 DBSOURCE REFSEQ: accession XM_039078903.2 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_086025) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_036323735.1-RS_2024_02 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 02/09/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..1521 /organism="Rattus norvegicus" /strain="BN/NHsdMcwi" /bio_material="RGD 61498" /db_xref="taxon:10116" /chromosome="7" /sex="male" /tissue_type="kidney, spleen, liver" /geo_loc_name="USA: Wisconsin, Milwaukee" /lat_lon="43.05 N 88.04 W" /collected_by="Rebecca Schilling, Melinda Dwinell" Protein 1..1521 /product="leucine-rich repeat serine/threonine-protein kinase 2 isoform X5" /calculated_mol_wt=170278 Region 889..1278 /region_name="LRR" /note="Leucine-rich repeat (LRR) protein [Transcription]; COG4886" /db_xref="CDD:443914" Region 984..1011 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1012..1035 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1036..1058 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1059..1083 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1084..1107 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1108..1129 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1130..1173 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1174..1196 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1197..1220 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1221..1245 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275380" Region 1333..1506 /region_name="RocCOR" /note="Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family; cd09914" /db_xref="CDD:206741" Site 1340..1347 /site_type="other" /note="G1 box" /db_xref="CDD:206741" Site order(1345..1348,1396,1451..1452,1454,1488..1490) /site_type="other" /note="GTP/Mg2+ binding site [chemical binding]" /db_xref="CDD:206741" Site 1367 /site_type="other" /note="G2 box" /db_xref="CDD:206741" Site 1371..1373 /site_type="other" /note="Switch I region" /db_xref="CDD:206741" Site 1393..1396 /site_type="other" /note="G3 box" /db_xref="CDD:206741" Site order(1395..1396,1412..1413) /site_type="other" /note="Switch II region" /db_xref="CDD:206741" Site 1451..1454 /site_type="other" /note="G4 box" /db_xref="CDD:206741" Site 1488..1490 /site_type="other" /note="G5 box" /db_xref="CDD:206741" CDS 1..1521 /gene="Lrrk2" /coded_by="XM_039078903.2:1..4566" /db_xref="GeneID:300160" /db_xref="RGD:1561168" ORIGIN 1 masgacqgcd eeeeeealkk livrlnnvqe gkqietllql ledilvftys drasklfegk 61 nvhvpllivl dsymrvasvq qvgwsllckl ievcpgtlqs ligpqdignd wevlgihrli 121 lkmltvhhan vnlsivglka ldllldsgki tllildeecd vfllifdamh rysaneevqk 181 lackalhvlf ervseeqlte fvenkdymtl lstfrsfkrd eeivhhvlcc lhslavtcsn 241 vevlmsgnvr cynivveamk tfptseniqe vscsllhklt lgnffnilvl nevhvfvvka 301 vqrypenval qisalsclal ltetiflnqd leersetqen sdedsekpfw lepcykalmr 361 hrknkhvqea acwalnnllm yqsslhekig dedgqfpahr evmlsmlmhs sskdvfqaaa 421 halstlleqn vnfrkillak gvylnvlelm qrhaqvpeva esgckmlshl fegsnpsldt 481 vaavipkilt vmrthgtsls vqlealrall hfvvpgvsed srddsrcqpn vlrtqcfrtd 541 ihklvlaaln rfignpgiqk cglkvissfa hlpdalemls lhgavdsvlh tlqmypddqe 601 iqclglhlmg clmtkknfci gtghllakil astlqrfkdv aevqttglqt vlsmldlsvs 661 fskllvhysf dvvmfhqmss gvleqkdeqf lnlcckcfak vavddelksk mleracdqnn 721 simvecllll gadanqakga tsliyqvcek esspklvell lnsgcreqdv rkaltvsiqk 781 gdnqvislll rrlaldlann siclggfcig kldpswlgpl fpdkssnlrk qtnagsvlar 841 kvlryqmrnt lqegvasgse gnfsedalak fgewtfipds smdsvfgqsd dldsegsess 901 flvkkksnsv svgevyrdla lqrcspnaqr hssslgpvfd hedllrrkrk ilssdeslrs 961 srlqshtrqs dsssslaser ehitsldlsa nelkdidalg qkcclsshle hltklelhqn 1021 sltsfpqqlc etlkclthld lhsnkfatfp sfmlkmpsvi hldasrndig ptvvldpvvk 1081 cpslkqfnls ynqlssipen ldqvvekleq lllegnkisg icsplslkel kilnlsknhi 1141 pslpedflea cpkvesfsar mnflaampal pssitslkls qnsftcipea ifslphlrsl 1201 dmshnniehl pgpahwksln lrelifsknq istldlsenp hiwsrveklh lshnklkeip 1261 peigrlenlt sldvsynlel rsfpnemgkl skiwdlpldg lhlnfdfkhi gckakdiirf 1321 lqqrlkkavp ynrmklmivg ntgsgkttll qqlmkmkkse lgmqgatvgi dvrdwpiqir 1381 gkrkkdlvln vwdfagreef ysthphfmtq ralylavydl skgqaevdam kpwlfnikar 1441 assspvilvg thldvsdekq rkacigkitk ellnkrgfpt irdyhfvnat eesdalaklr 1501 ktiineslnf kvggcappag y //
Whole sequence Selected region from: to:
Conserved Domains
Show sequence Show gap features
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on