U.S. flag

An official website of the United States government

leucine-rich repeat serine/threonine-protein kinase 2 isoform X5 [Rattus norvegicus]

NCBI Reference Sequence: XP_038934831.1

Identical Proteins FASTA Graphics 

LOCUS       XP_038934831            1521 aa            linear   ROD 22-FEB-2024
DEFINITION  leucine-rich repeat serine/threonine-protein kinase 2 isoform X5
            [Rattus norvegicus].
ACCESSION   XP_038934831
VERSION     XP_038934831.1
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_039078903.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086025) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1521
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..1521
                     /product="leucine-rich repeat serine/threonine-protein
                     kinase 2 isoform X5"
                     /calculated_mol_wt=170278
     Region          889..1278
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          984..1011
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1012..1035
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1036..1058
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1059..1083
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1084..1107
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1108..1129
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1130..1173
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1174..1196
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1197..1220
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1221..1245
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          1333..1506
                     /region_name="RocCOR"
                     /note="Ras of complex proteins (Roc) C-terminal of Roc
                     (COR) domain family; cd09914"
                     /db_xref="CDD:206741"
     Site            1340..1347
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206741"
     Site            order(1345..1348,1396,1451..1452,1454,1488..1490)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206741"
     Site            1367
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206741"
     Site            1371..1373
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206741"
     Site            1393..1396
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206741"
     Site            order(1395..1396,1412..1413)
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206741"
     Site            1451..1454
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206741"
     Site            1488..1490
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206741"
     CDS             1..1521
                     /gene="Lrrk2"
                     /coded_by="XM_039078903.2:1..4566"
                     /db_xref="GeneID:300160"
                     /db_xref="RGD:1561168"
ORIGIN      
        1 masgacqgcd eeeeeealkk livrlnnvqe gkqietllql ledilvftys drasklfegk
       61 nvhvpllivl dsymrvasvq qvgwsllckl ievcpgtlqs ligpqdignd wevlgihrli
      121 lkmltvhhan vnlsivglka ldllldsgki tllildeecd vfllifdamh rysaneevqk
      181 lackalhvlf ervseeqlte fvenkdymtl lstfrsfkrd eeivhhvlcc lhslavtcsn
      241 vevlmsgnvr cynivveamk tfptseniqe vscsllhklt lgnffnilvl nevhvfvvka
      301 vqrypenval qisalsclal ltetiflnqd leersetqen sdedsekpfw lepcykalmr
      361 hrknkhvqea acwalnnllm yqsslhekig dedgqfpahr evmlsmlmhs sskdvfqaaa
      421 halstlleqn vnfrkillak gvylnvlelm qrhaqvpeva esgckmlshl fegsnpsldt
      481 vaavipkilt vmrthgtsls vqlealrall hfvvpgvsed srddsrcqpn vlrtqcfrtd
      541 ihklvlaaln rfignpgiqk cglkvissfa hlpdalemls lhgavdsvlh tlqmypddqe
      601 iqclglhlmg clmtkknfci gtghllakil astlqrfkdv aevqttglqt vlsmldlsvs
      661 fskllvhysf dvvmfhqmss gvleqkdeqf lnlcckcfak vavddelksk mleracdqnn
      721 simvecllll gadanqakga tsliyqvcek esspklvell lnsgcreqdv rkaltvsiqk
      781 gdnqvislll rrlaldlann siclggfcig kldpswlgpl fpdkssnlrk qtnagsvlar
      841 kvlryqmrnt lqegvasgse gnfsedalak fgewtfipds smdsvfgqsd dldsegsess
      901 flvkkksnsv svgevyrdla lqrcspnaqr hssslgpvfd hedllrrkrk ilssdeslrs
      961 srlqshtrqs dsssslaser ehitsldlsa nelkdidalg qkcclsshle hltklelhqn
     1021 sltsfpqqlc etlkclthld lhsnkfatfp sfmlkmpsvi hldasrndig ptvvldpvvk
     1081 cpslkqfnls ynqlssipen ldqvvekleq lllegnkisg icsplslkel kilnlsknhi
     1141 pslpedflea cpkvesfsar mnflaampal pssitslkls qnsftcipea ifslphlrsl
     1201 dmshnniehl pgpahwksln lrelifsknq istldlsenp hiwsrveklh lshnklkeip
     1261 peigrlenlt sldvsynlel rsfpnemgkl skiwdlpldg lhlnfdfkhi gckakdiirf
     1321 lqqrlkkavp ynrmklmivg ntgsgkttll qqlmkmkkse lgmqgatvgi dvrdwpiqir
     1381 gkrkkdlvln vwdfagreef ysthphfmtq ralylavydl skgqaevdam kpwlfnikar
     1441 assspvilvg thldvsdekq rkacigkitk ellnkrgfpt irdyhfvnat eesdalaklr
     1501 ktiineslnf kvggcappag y
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Reference sequence information

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.