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carboxylesterase 2J isoform X1 [Rattus norvegicus]

NCBI Reference Sequence: XP_038953911.1

Identical Proteins FASTA Graphics 

LOCUS       XP_038953911             576 aa            linear   ROD 22-FEB-2024
DEFINITION  carboxylesterase 2J isoform X1 [Rattus norvegicus].
ACCESSION   XP_038953911
VERSION     XP_038953911.1
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_039097983.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086037) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..576
                     /product="carboxylesterase 2J isoform X1"
                     /calculated_mol_wt=63931
     Region          50..555
                     /region_name="COesterase"
                     /note="Carboxylesterase family; pfam00135"
                     /db_xref="CDD:395084"
     Site            order(165..167,244..246,249,384,388..389,428,475,478)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238191"
     Site            order(245,362,474)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238191"
     CDS             1..576
                     /gene="Ces2j"
                     /coded_by="XM_039097983.2:1525..3255"
                     /db_xref="GeneID:685645"
                     /db_xref="RGD:1591368"
ORIGIN      
        1 mlfvisapfp cfpptldsre kglrrererk kgipdsnlhs flteqgqdsa spirnthtgq
       61 vrgsfvhvkd tksgihtflg ipfakppvgp lrfappedpe pwsgvrdats qpamclqtam
      121 mnlegmkete ltklpmsedc lylniyvpah ahedsnlpvm vwihggglvg gsasmndast
      181 laateeiviv siqyrlgvlg ffstgdqhar gnwgyldqma alrwvqqnia yfggnrdsvt
      241 ifgvsaggts vsshvvspms kglfhraimq sgvallpgli sdtsevvykt vanlsgceas
      301 dsealirclr akskqeilai nqvfkmipgv vdgkflpkhp qellaskdfh pvpsiigvnt
      361 decgwgvpti lglyhiinni tretlpaalk iaaaqmmlpp ecidlimeey mgdtedaetl
      421 qaqfkemlgd fifvipalqv ahfqrsqapv yfyefqhlls fikqvrpfyp kadhgddtvf
      481 vfgsyfwgmt fdlteeeell krrvmkywan fartgnpnge dlphwpvldh deqylqlnsq
      541 pavgralkar rlqfwtktlp qkiqelkgsq skhael
//
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