Protein Family Models

This family includes human Protein O-mannosyl-transferase TMEM260 and similar sequences from bacteria and eukaryota. TMEM260 transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins [1]. [1]. 37186866. The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase. Larsen ISB, Povolo L, Zhou L, Tian W, Mygind KJ, Hintze J, Jiang C, Hartill V, Prescott K, Johnson CA, Mullegama SV, McConkie-Rosell A, McDonald M, Hansen L, Vakhrushev SY, Schjoldager KT, Clausen H, Worzfeld T, Joshi HJ, Halim A;. Proc Natl Acad Sci U S A. 2023;120:e2302584120. (from Pfam)

Date:

2024-10-16

DUF2723 domain-containing protein similar to vertebrate transmembrane protein 260

Date:

2021-01-26