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    Mir190a-2 microRNA mir-190a-2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 104796140, updated on 17-Aug-2024

    Summary

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    Symbol
    Mir190a-2provided by RGD
    Full Name
    microRNA mir-190a-2provided by RGD
    Primary source
    RGD:14398603
    See related
    miRBase:MI0031759; AllianceGenome:RGD:14398603
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    rno-mir-190a-2
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 8

    Bibliography

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    Related articles in PubMed

    1. New microRNAs from mouse and human. Lagos-Quintana M, et al. RNA, 2003 Feb. PMID 12554859, Free PMC Article
    2. Small RNA expression and strain specificity in the rat. Linsen SE, et al. BMC Genomics, 2010 Apr 19. PMID 20403161, Free PMC Article
    3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • microRNA 190a-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_128682.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AABR07070704

    Gene LinkOut

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