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    SIRPA signal regulatory protein alpha [ Macaca nemestrina (pig-tailed macaque) ]

    Gene ID: 105481633, updated on 13-Mar-2024

    Summary

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    Gene symbol
    SIRPA
    Gene description
    signal regulatory protein alpha
    See related
    Ensembl:ENSMNEG00000018475
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca nemestrina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SIRPA in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012018910.1 (14385648..14432556, complement)

    NW_012018910.1Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 35 Neighboring gene uncharacterized LOC105481650 Neighboring gene prodynorphin Neighboring gene tyrosine-protein phosphatase non-receptor type substrate 1-like Neighboring gene uncharacterized LOC105481631 Neighboring gene signal-regulatory protein beta-1-like Neighboring gene 60S ribosomal protein L29-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012018910 Unplaced Scaffold Reference Mnem_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein phosphatase non-receptor type substrate 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mnem_1.0

    Genomic

    1. NW_012018910.1 Reference Mnem_1.0

      Range
      14385648..14432556 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011741366.2 → XP_011739668.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

      UniProtKB/TrEMBL
      A0A2K6AXU0, A0A2K6AXU3
      Related
      ENSMNEP00000003963.1, ENSMNET00000020204.1
      Conserved Domains (4) summary
      cd00098
      Location:265 → 338
      IgC; Immunoglobulin Constant domain
      smart00410
      Location:41 → 143
      IG_like; Immunoglobulin like
      pfam07686
      Location:38 → 144
      V-set; Immunoglobulin V-set domain
      cl11960
      Location:142 → 253
      Ig; Immunoglobulin domain

    2. XM_011741365.2 → XP_011739667.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0A2K6AXT8, A0A2K6AXU3
      Related
      ENSMNEP00000003965.1, ENSMNET00000020218.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    3. XM_024792817.1 → XP_024648585.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0A2K6AXT8, A0A2K6AXU3
      Related
      ENSMNEP00000003970.1, ENSMNET00000020237.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)
    Nucleotide Protein
    Heading Accession and Version

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