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    ARHGAP24 Rho GTPase activating protein 24 [ Numida meleagris (helmeted guineafowl) ]

    Gene ID: 110398629, updated on 15-Mar-2024

    Summary

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    Gene symbol
    ARHGAP24
    Gene description
    Rho GTPase activating protein 24
    See related
    Ensembl:ENSNMEG00000016935
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Numida meleagris
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP24 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    100 current NumMel1.0 (GCF_002078875.1) 4 NC_034412.1 (51267251..51427777, complement)

    Chromosome 4 - NC_034412.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 13 Neighboring gene mitogen-activated protein kinase 10 Neighboring gene uncharacterized LOC110398631 Neighboring gene uncharacterized LOC110398888 Neighboring gene COP9 signalosome subunit 4 Neighboring gene lin-54 DREAM MuvB core complex component

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_034412.1 Chromosome 4 Reference NumMel1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of Rac protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of ruffle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in wound healing, spreading of epidermal cells IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NumMel1.0 Primary Assembly

    Genomic

    1. NC_034412.1 Reference NumMel1.0 Primary Assembly

      Range
      51267251..51427777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021396478.1 → XP_021252153.1  rho GTPase-activating protein 24 isoform X1

      Conserved Domains (3) summary
      cd04390
      Location:131 → 329
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13379
      Location:18 → 131
      PH_RhoGap24; Rho GTPase activating protein 24 Pleckstrin homology (PH) domain
      cl25732
      Location:585 → 722
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_021396475.1 → XP_021252150.1  rho GTPase-activating protein 24 isoform X1

      Related
      ENSNMEP00000019654.1, ENSNMET00000028733.1
      Conserved Domains (3) summary
      cd04390
      Location:131 → 329
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13379
      Location:18 → 131
      PH_RhoGap24; Rho GTPase activating protein 24 Pleckstrin homology (PH) domain
      cl25732
      Location:585 → 722
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_021396474.1 → XP_021252149.1  rho GTPase-activating protein 24 isoform X1

      Conserved Domains (3) summary
      cd04390
      Location:131 → 329
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13379
      Location:18 → 131
      PH_RhoGap24; Rho GTPase activating protein 24 Pleckstrin homology (PH) domain
      cl25732
      Location:585 → 722
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_021396481.1 → XP_021252156.1  rho GTPase-activating protein 24 isoform X3

      Conserved Domains (3) summary
      cd04390
      Location:36 → 234
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl17171
      Location:1 → 36
      PH-like; Pleckstrin homology-like domain
      cl25732
      Location:490 → 627
      SMC_N; RecF/RecN/SMC N terminal domain

    5. XM_021396477.1 → XP_021252152.1  rho GTPase-activating protein 24 isoform X3

      Conserved Domains (3) summary
      cd04390
      Location:36 → 234
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl17171
      Location:1 → 36
      PH-like; Pleckstrin homology-like domain
      cl25732
      Location:490 → 627
      SMC_N; RecF/RecN/SMC N terminal domain

    6. XM_021396479.1 → XP_021252154.1  rho GTPase-activating protein 24 isoform X3

      Conserved Domains (3) summary
      cd04390
      Location:36 → 234
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl17171
      Location:1 → 36
      PH-like; Pleckstrin homology-like domain
      cl25732
      Location:490 → 627
      SMC_N; RecF/RecN/SMC N terminal domain

    7. XM_021396476.1 → XP_021252151.1  rho GTPase-activating protein 24 isoform X2

      Conserved Domains (2) summary
      cd04390
      Location:39 → 237
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl25732
      Location:493 → 630
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein
    Heading Accession and Version

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