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    FZD4 frizzled class receptor 4 [ Vulpes vulpes (red fox) ]

    Gene ID: 112932336, updated on 15-Mar-2024

    Summary

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    Gene symbol
    FZD4
    Gene description
    frizzled class receptor 4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Vulpes vulpes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
    Orthologs
    human mouse all
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    Genomic context

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    See FZD4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356544.1 (5314797..5338902, complement)

    NW_020356544.1Genomic Context describing neighboring genes Neighboring gene serine protease 23 Neighboring gene U6 spliceosomal RNA Neighboring gene cofilin-2 pseudogene Neighboring gene transmembrane protein 135

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020356544 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in retina vasculature morphogenesis in camera-type eye IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    frizzled-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference VulVul2.2 Primary Assembly

    Genomic

    1. NW_020356544.1 Reference VulVul2.2 Primary Assembly

      Range
      5314797..5338902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026015268.1 → XP_025871053.1  frizzled-4

      UniProtKB/TrEMBL
      A0A3Q7TN04
      Conserved Domains (2) summary
      cd07448
      Location:174 → 299
      CRD_FZ4; Cysteine-rich Wnt-binding domain of the frizzled 4 (Fz4) receptor
      cd15038
      Location:341 → 641
      7tmF_FZD4; class F frizzled subfamily 4, member of 7-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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