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    GRIN1 glutamate ionotropic receptor NMDA type subunit 1 [ Halichoerus grypus (gray seal) ]

    Gene ID: 118518239, updated on 20-Mar-2024

    Summary

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    Gene symbol
    GRIN1
    Gene description
    glutamate ionotropic receptor NMDA type subunit 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Halichoerus grypus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Halichoerus
    Orthologs
    human mouse all
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    Genomic context

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    See GRIN1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current Tufts_HGry_1.1 (GCF_012393455.1) Unplaced Scaffold NW_023401183.1 (46256..69871)

    NW_023401183.1Genomic Context describing neighboring genes Neighboring gene endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase-like Neighboring gene uncharacterized LOC118518246 Neighboring gene uncharacterized LOC118518245 Neighboring gene leucine rich repeat containing 26 Neighboring gene transmembrane protein 210

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023401183 Unplaced Scaffold Reference Tufts_HGry_1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NMDA glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ionotropic glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NMDA selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, NMDA 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Halichoerus grypus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tufts_HGry_1.1

    Genomic

    1. NW_023401183.1 Reference Tufts_HGry_1.1

      Range
      46256..69871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036064904.1 → XP_035920797.1  glutamate receptor ionotropic, NMDA 1 isoform X5

      Conserved Domains (3) summary
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    2. XM_036064905.1 → XP_035920798.1  glutamate receptor ionotropic, NMDA 1 isoform X6

      Conserved Domains (3) summary
      cd13719
      Location:371 → 775
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 359
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:811 → 839
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    3. XM_036064901.1 → XP_035920794.1  glutamate receptor ionotropic, NMDA 1 isoform X2

      Conserved Domains (3) summary
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    4. XM_036064909.1 → XP_035920802.1  glutamate receptor ionotropic, NMDA 1 isoform X10

      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    5. XM_036064900.1 → XP_035920793.1  glutamate receptor ionotropic, NMDA 1 isoform X1

      Conserved Domains (3) summary
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    6. XM_036064908.1 → XP_035920801.1  glutamate receptor ionotropic, NMDA 1 isoform X9

      Conserved Domains (3) summary
      cd13719
      Location:350 → 754
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 338
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:790 → 818
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    7. XM_036064902.1 → XP_035920795.1  glutamate receptor ionotropic, NMDA 1 isoform X3

      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    8. XM_036064907.1 → XP_035920800.1  glutamate receptor ionotropic, NMDA 1 isoform X8

      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    9. XM_036064906.1 → XP_035920799.1  glutamate receptor ionotropic, NMDA 1 isoform X7

      Conserved Domains (3) summary
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    10. XM_036064903.1 → XP_035920796.1  glutamate receptor ionotropic, NMDA 1 isoform X4

      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    11. XM_036064910.1 → XP_035920803.1  glutamate receptor ionotropic, NMDA 1 isoform X11

      Conserved Domains (3) summary
      cd13719
      Location:325 → 729
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10562
      Location:765 → 793
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
      cl10011
      Location:42 → 313
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version

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