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    Nepn nephrocan [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309775, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nepnprovided by RGD
    Official Full Name
    nephrocanprovided by RGD
    Primary source
    RGD:1307755
    See related
    EnsemblRapid:ENSRNOG00000000410 AllianceGenome:RGD:1307755
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307755
    Summary
    Predicted to be involved in extracellular matrix organization; negative regulation of transcription by RNA polymerase II; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in interstitial matrix. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 1.9), Heart (RPKM 0.8) and 6 other tissues See more
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    Genomic context

    See Nepn in Genome Data Viewer
    Location:
    20q11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (32329314..32342162)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (31786607..31799458)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (33527932..33543860)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene golgi associated PDZ and coiled-coil motif containing Neighboring gene uncharacterized LOC134483928 Neighboring gene NUS1 dehydrodolichyl diphosphate synthase subunit Neighboring gene actin-related protein 2/3 complex subunit 2-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001414970.1NP_001401899.1  nephrocan precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A8I6AJL1, A6K483, A6K484, D3ZHG5
      Related
      ENSRNOP00000093322.1, ENSRNOT00000099270.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      32329314..32342162
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001107632.1: Suppressed sequence

      Description
      NM_001107632.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.