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    Ankrd12 ankyrin repeat domain 12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316775, updated on 9-Dec-2024

    Summary

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    Symbol
    Ankrd12provided by RGD
    Full Name
    ankyrin repeat domain 12provided by RGD
    Primary source
    RGD:1310118
    See related
    EnsemblRapid:ENSRNOG00000012733 AllianceGenome:RGD:1310118
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human ANKRD12 (ankyrin repeat domain 12). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 156.4), Brain (RPKM 124.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd12 in Genome Data Viewer
    Location:
    9q37
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (113030127..113134816, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (105583273..105687957, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (113605683..113682482)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480622 Neighboring gene twisted gastrulation BMP signaling modulator 1 Neighboring gene basic proline-rich protein-like Neighboring gene NADH:ubiquinone oxidoreductase core subunit V2 Neighboring gene uncharacterized LOC120094769 Neighboring gene WASH complex subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 12
    Names
    ankyrin repeat domain-containing protein 12-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108238.1 → NP_001101708.1  ankyrin repeat domain-containing protein 12

      See identical proteins and their annotated locations for NP_001101708.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473997
      UniProtKB/TrEMBL
      A6JRD8, D3ZCH1
      Related
      ENSRNOP00000017613.4, ENSRNOT00000017613.8
      Conserved Domains (4) summary
      PTZ00121
      Location:368 → 1011
      PTZ00121; MAEBL; Provisional
      PTZ00108
      Location:916 → 1202
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:184 → 215
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:189 → 277
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      113030127..113134816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039083803.2 → XP_038939731.1  ankyrin repeat domain-containing protein 12 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZN78
      Related
      ENSRNOP00000079645.1, ENSRNOT00000096339.2
      Conserved Domains (4) summary
      PTZ00121
      Location:345 → 988
      PTZ00121; MAEBL; Provisional
      PTZ00108
      Location:893 → 1179
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:161 → 192
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:166 → 254
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_063267349.1 → XP_063123419.1  ankyrin repeat domain-containing protein 12 isoform X3

    3. XM_039083802.2 → XP_038939730.1  ankyrin repeat domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A6JRD8, D3ZCH1
      Conserved Domains (4) summary
      PTZ00121
      Location:368 → 1011
      PTZ00121; MAEBL; Provisional
      PTZ00108
      Location:916 → 1202
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:184 → 215
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:189 → 277
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_063267348.1 → XP_063123418.1  ankyrin repeat domain-containing protein 12 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZN78

    5. XM_063267347.1 → XP_063123417.1  ankyrin repeat domain-containing protein 12 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZN78

    6. XM_039083801.2 → XP_038939729.1  ankyrin repeat domain-containing protein 12 isoform X1

      UniProtKB/TrEMBL
      A6JRD8, D3ZCH1
      Conserved Domains (4) summary
      PTZ00121
      Location:368 → 1011
      PTZ00121; MAEBL; Provisional
      PTZ00108
      Location:916 → 1202
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:184 → 215
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:189 → 277
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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