Il22ra1 interleukin 22 receptor subunit alpha 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Il22ra1provided by RGD
Official Full Name: interleukin 22 receptor subunit alpha 1provided by RGD
Primary source: RGD:1559655
See related: EnsemblRapid:ENSRNOG00000066331 AllianceGenome:RGD:1559655
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1559655
Summary: Predicted to enable interleukin-20 binding activity and interleukin-22 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and negative regulation of inflammatory response. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be active in plasma membrane. Orthologous to human IL22RA1 (interleukin 22 receptor subunit alpha 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 8.0), Testes (RPKM 7.3) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (153245067..153269865)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (147961496..147986296)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (154078093..154102903)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cytokine receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables interleukin-20 binding	ISO Inferred from Sequence Orthology more info
enables interleukin-22 receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cytokine-mediated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within defense response to Gram-negative bacterium	ISO Inferred from Sequence Orthology more info
involved_in interleukin-22-mediated signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of inflammatory response	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: interleukin-22 receptor subunit alpha-1

Names: interleukin 22 receptor, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191869.1 → NP_001178798.1 interleukin-22 receptor subunit alpha-1 precursor

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000005

UniProtKB/TrEMBL

A0A8I6A0L8, A6IT64

Related

ENSRNOP00000085647.1, ENSRNOT00000109990.2

Conserved Domains (1) summary

pfam01108
Location:26 → 107

Tissue_fac; Tissue factor