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Report for CCDS1538.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
1538.1 Public Homo sapiens 1 TP53BP2 24 110 108 CCDS HistoryNCBI Gene:7159Re-query CCDS DB by CCDS ID:1538.1Re-query CCDS DB by GeneID:7159See the combined annotation on chromosome 1 in Sequence Viewer

Public Note for CCDS 1538.1
This CCDS ID represents the short isoform encoded by this gene. It is also known as 53BP2S, and is described in PMIDs 8668206 and 14766226. This isoform is shorter at the N-terminus compared to the full-length isoform, also known as 53BP2L and represented by CCDS44319.1. The presence of an upstream in-frame start codon, use of which would extend the short isoform N-terminus by 62 aa, should be noted. This has a weak Kozak signal compared to a strong Kozak signal for the represented downstream start codon; the use of the downstream start codon is also supported by in vitro translation experiments in PMID:8668206.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
CDS uses downstream AUG

Sequence IDs included in CCDS 1538.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000391878.6 ENSP00000375750.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000391878.6Link to Ensembl Protein Viewer:ENSP00000375750.2Re-query CCDS DB by Nucleotide ID:ENST00000391878Re-query CCDS DB by Protein ID:ENSP00000375750
Original member Current member NCBI NM_005426.3 NP_005417.1 Accepted alive Link to Nucleotide Sequence:NM_005426.3Link to Protein Sequence:NP_005417.1Re-query CCDS DB by Nucleotide ID:NM_005426Re-query CCDS DB by Protein ID:NP_005417Link to BLAST:NP_005417.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_005417.1 1005 Q13625-2 1005 100% 0 0

Chromosomal Locations for CCDS 1538.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 1 (NC_000001.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1See the combined annotation on chromosome 1 in Sequence Viewer

Chromosome Start Stop Links
1 223780853 223780894 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223784115 223784314 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223789008 223789174 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223792389 223792522 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223793303 223793440 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223795815 223796590 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223798215 223798677 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223799899 223800047 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223800700 223800810 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223802116 223802344 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223802731 223802895 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223803271 223803452 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223804174 223804348 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 223806846 223806932 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (3018 nt):
ATGGATCTGACTCTTGCTGAACTTCAGGAAATGGCATCTCGCCAGCAGCAACAGATTGAAGCCCAGCAAC
AATTGCTGGCAACTAAGGAACAGCGCTTAAAGTTTTTGAAACAACAAGATCAGCGACAACAGCAACAAGT
TGCTGAGCAGGAGAAACTTAAAAGGCTAAAAGAAATAGCTGAGAATCAGGAAGCTAAGCTAAAAAAAGTG
AGAGCACTTAAAGGCCACGTGGAACAGAAGAGACTAAGCAATGGGAAACTTGTGGAGGAAATTGAACAGA
TGAATAATTTGTTCCAGCAAAAACAGAGGGAGCTCGTCCTGGCTGTGTCAAAAGTAGAAGAACTGACCAG
GCAGCTAGAGATGCTCAAGAACGGCAGGATCGACAGCCACCATGACAATCAGTCTGCAGTGGCTGAGCTT
GATCGCCTCTATAAGGAGCTGCAGCTAAGAAACAAATTGAATCAAGAGCAGAATGCCAAGCTACAACAAC
AGAGGGAGTGTTTGAATAAGCGTAATTCAGAAGTGGCAGTCATGGATAAGCGTGTTAATGAGCTGAGGGA
CCGGCTGTGGAAGAAGAAGGCAGCTCTACAGCAAAAAGAAAATCTACCAGTTTCATCTGATGGAAATCTT
CCCCAGCAAGCCGCGTCAGCCCCAAGCCGTGTGGCTGCAGTAGGTCCCTATATCCAGTCGTCTACTATGC
CTCGGATGCCCTCAAGGCCTGAATTGCTGGTGAAGCCAGCCCTGCCGGATGGTTCCTTGGTCATTCAGGC
TTCAGAGGGGCCGATGAAAATACAGACACTGCCCAACATGAGATCTGGGGCTGCTTCACAAACTAAAGGC
TCTAAAATCCATCCAGTTGGCCCTGATTGGAGTCCTTCAAATGCAGATCTTTTCCCAAGCCAAGGCTCTG
CTTCTGTACCTCAAAGCACTGGGAATGCTCTGGATCAAGTTGATGATGGAGAGGTTCCGCTGAGGGAGAA
AGAGAAGAAAGTGCGTCCGTTCTCAATGTTTGATGCAGTAGACCAGTCCAATGCCCCACCTTCCTTTGGT
ACTCTGAGGAAGAACCAGAGCAGTGAAGATATCTTGCGGGATGCTCAGGTTGCAAATAAAAATGTGGCTA
AAGTACCACCTCCTGTTCCTACAAAACCAAAACAGATTAATTTGCCTTATTTTGGACAAACTAATCAGCC
ACCTTCAGACATTAAGCCAGACGGAAGTTCTCAGCAGTTGTCAACAGTTGTTCCGTCCATGGGAACTAAA
CCAAAACCAGCAGGGCAGCAGCCGAGAGTGCTGCTATCTCCCAGCATACCTTCGGTTGGCCAAGACCAGA
CCCTTTCTCCAGGTTCTAAGCAAGAAAGTCCACCTGCTGCTGCCGTCCGGCCCTTTACTCCCCAGCCTTC
CAAAGACACCTTACTTCCACCCTTCAGAAAACCCCAGACCGTGGCAGCAAGTTCAATATATTCCATGTAT
ACGCAACAGCAGGCGCCAGGAAAAAACTTCCAGCAGGCTGTGCAGAGCGCGTTGACCAAGACTCATACCA
GAGGGCCACACTTTTCAAGTGTATATGGTAAGCCTGTAATTGCTGCTGCCCAGAATCAACAGCAGCACCC
AGAGAACATTTATTCCAATAGCCAGGGCAAGCCTGGCAGTCCAGAACCTGAAACAGAGCCTGTTTCTTCA
GTTCAGGAGAACCATGAAAACGAAAGAATTCCTCGGCCACTCAGCCCAACTAAATTACTGCCTTTCTTAT
CTAATCCTTACCGAAACCAGAGTGATGCTGACCTAGAAGCCTTACGAAAGAAACTGTCTAACGCACCAAG
GCCTCTAAAGAAACGTAGTTCTATTACAGAGCCAGAGGGTCCTAATGGGCCAAATATTCAGAAGCTTTTA
TATCAGAGGACCACCATAGCGGCCATGGAGACCATCTCTGTCCCATCATACCCATCCAAGTCAGCTTCTG
TGACTGCCAGCTCAGAAAGCCCAGTAGAAATCCAGAATCCATATTTACATGTGGAGCCCGAAAAGGAGGT
GGTCTCTCTGGTTCCTGAATCATTGTCCCCAGAGGATGTGGGGAATGCCAGTACAGAGAACAGTGACATG
CCAGCTCCTTCTCCAGGCCTTGATTATGAGCCTGAGGGAGTCCCAGACAACAGCCCAAATCTCCAGAATA
ACCCAGAAGAACCAAATCCAGAGGCTCCACATGTGCTTGATGTGTACCTGGAGGAGTACCCTCCATACCC
ACCCCCACCATACCCATCTGGGGAGCCTGAAGGGCCCGGAGAAGACTCGGTGAGCATGCGCCCGCCTGAA
ATCACCGGGCAGGTCTCTCTGCCTCCTGGTAAAAGGACAAACTTGCGTAAAACTGGCTCAGAGCGTATCG
CTCATGGAATGAGGGTGAAATTCAACCCCCTTGCTTTACTGCTAGATTCGTCTTTGGAGGGAGAATTTGA
CCTTGTACAGAGAATTATTTATGAGGTTGATGACCCAAGCCTCCCCAATGATGAAGGCATCACGGCTCTT
CACAATGCTGTGTGTGCAGGCCACACAGAAATCGTTAAGTTCCTGGTACAGTTTGGTGTAAATGTAAATG
CTGCTGATAGTGATGGATGGACTCCATTACATTGTGCTGCCTCATGTAACAACGTCCAAGTGTGTAAGTT
TTTGGTGGAGTCAGGAGCCGCTGTGTTTGCCATGACCTACAGTGACATGCAGACTGCTGCAGATAAGTGC
GAGGAAATGGAGGAAGGCTACACTCAGTGCTCCCAATTTCTTTATGGAGTTCAGGAGAAGATGGGCATAA
TGAATAAAGGAGTCATTTATGCGCTTTGGGATTATGAACCTCAGAATGATGATGAGCTGCCCATGAAAGA
AGGAGACTGCATGACAATCATCCACAGGGAAGACGAAGATGAAATCGAATGGTGGTGGGCGCGCCTTAAT
GATAAGGAGGGATATGTTCCACGTAACTTGCTGGGACTGTACCCAAGAATTAAACCAAGACAAAGGAGCT
TGGCCTGA

Translation (1005 aa):
MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKV
RALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAEL
DRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNL
PQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKG
SKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFG
TLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK
PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMY
TQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSS
VQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLL
YQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDM
PAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPE
ITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL
HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKC
EEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLN
DKEGYVPRNLLGLYPRIKPRQRSLA


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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