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Report for CCDS38303.2 (current version)
CCDS |
Status |
Species |
Chrom. |
Gene |
CCDS Release |
NCBI Annotation Release |
Ensembl Annotation Release |
Links |
38303.2 |
Public |
Mus musculus |
2 |
Mroh8 |
23 |
108 |
98 |
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Public Note for CCDS 38303.2 |
The coding region has been updated to extend the N-terminus to one that is more supported by the available transcript and conservation data. The transcript is predicted to be a candidate for nonsense-mediated mRNA decay (NMD), but the protein is represented because the gene is believed to be protein-coding based on good conservation of the CDS, and because all currently available mouse transcripts (AK029507.1, AK132763.1 and BC150937.1) are NMD candidates. Furthermore, the stop codon is only 56 nts from the last splice site, which suggests that the transcript is only marginally an NMD candidate and may escape NMD at least some of the time. |
Public since: CCDS release 4, NCBI annotation release 37.1, Ensembl annotation release 47
Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)
Attributes |
Nonsense-mediated decay (NMD) candidate |
Sequence IDs included in CCDS 38303.2
Original |
Current |
Source |
Nucleotide ID |
Protein ID |
Status in CCDS |
Seq. Status |
Links |
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EBI |
ENSMUST00000143663.1 |
ENSMUSP00000124362.1 |
Accepted |
alive |
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NCBI |
NM_001039557.4 |
NP_001034646.2 |
Accepted |
alive |
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Chromosomal Locations for CCDS 38303.2
Assembly GRCm38.p6 (GCF_000001635.26)
CCDS Sequence Data |
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Blue highlighting indicates alternating exons. | Red highlighting indicates amino acids encoded across a splice junction. | | Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. |
Nucleotide Sequence (3150 nt): ATGCCCCTGCCCCGTAGGGGAGGGGAACCGCGCCTAGCCGGCGCCCGTGTGGTCCGCACTAGCCTCCCGC GGGCGACGCCCCGCTCCCCAAAGCGTGTCGGCCGCGGGGCCCCACTATTGAGCCATGCGCAACGCCTCAC CCGGCGGCGCCATTCCTCCGAGCAGGTCCCACCGGAGCCCGAGCAGGCAGACTTCCGCTCCGGGAAGTGG CTCCAAGAGCGCGCCGGAGGGGACGCCAGGGACCCGCGGCACACGCCACTTGCCAGAATGGGCTCCCGGC AAAGGGCCAGCGGTACAGAAGAAGTAGTGATCCCCTGTGCTTCTGACAGTGACTCAGGGAGTGTAGACCT GCAGCTGAGCAACTTAGACGACGTTCAAAAGGGTGGAGCTAGTGTTGAATTCACAGATTCGGACATCGCT GACATCCCTACACTGCCTCAGGAGTCCCTGCCAGATAACCTCAGGTTACTTACTCTCCAGGAGCCCCTCA GTGAGACCAGCATTGAGAGACTGGTCCAGTCCATCCAGGAAGTTTTACATGGTGAGCTAAAGGGGGAAAC TCAAAAGTTGAAGTTCCTAAGATCTTTGTCTTCTTTGAGCCAAACTATACCTTATGACGAAAACACGGAA TCATTTATTCACCGCCACACAGCAGAAATAGTGCATGTTCTAAGTGTGTTGGTACAGGAGGAGCCTCTGC ACTCTCTAACCAGCATGGTGCGCCAGGAGATCTTTGTCACCATCACTGACCTCAGTTTCCAAAATGTGTA CCTGTTGTTTGGCTCTGAAGACCGAGAGGACTTGCTTGGGCTTATCACCAAAAGTATAATCTCTCTGCCC GCCACAAGCACCCCTATCCAGCTGCTGAAGATAGTGTCCAACCAGGCCATCGAGCAAGAGTGTCTCTACA GGGAGACGTTCGAGGCCTTTTCTGTGATGCTGCAGAGTCTGGTAATAAAAGATCCACATCTGGAATTTTT TGACAGCATTTTTAAGCACATAGACCCCTGGTTACAGTCCGACAGAGACCATGAGCGGGAACGGGCTACC ACTGTCATGGCCCAAGTTCTCAAATGCTTATCCAGTTATCTCAGCCTGAAGCTTCCACTGCAGTTCCAGA GGCTCGGGAATCTCGTGGCTGTGATGGCGCTGCTGTGTGGGGACCCACAGAAAGAGGTGGCTGAGGAGGC TGCAGAGGGGACACACTACCTGCTTCATATCACTCTGAGACTGAAATATATCATGCAGGACAGAGACAAC AATAGCAAGAACTTGAGAGAAACTTTGAAAAAATGCAGGTTGCTGCTGGAGCAATATAGCCTCAAACGGT TCTACTGCTGTCCCTACAAGATTGTTCAGGTCTTTGAAGTTTTCCTCGACTCTCGGGAGCTCGGCCAGTT TATCATGACGATATTGGACAGCCTGAAAAATCTGCCGCATCCCTGTATCCAGCAGACAGCAGGAGAGTTG CTGATAACCTTGGTGAAGAGTGCAGAGGCTCGGTTTGAGAGGGTGCCAGAAATAGTAGGTGTGATCTGTG CTCGGCTGTCGATAATCACCCTGACTAGTGTCCGGCAACAGATCATAAATACTGTGAGTCTGTTTGTCTC CAGACCTAAGTACACAGATGTAGTGCTCAGCCACCTTTTATGCCATCCAGTACCGTATGACAGGCATCTG GCTGAATTGTGGAGATCCCTGGAGGTAGAGCTGTCCAACACGACCTGGGTCCTATGGAGGCTCCTGCGGA AGCTGCAGAAGTGCCACGAGGGGCCCAGCCAGGAGAAGATGGCCTACGTGGCTGTTGCTGTGACCGATGC CCTTTATGAGGTGCTCATGGGGAACAAACTCCGAGCAGCCGCATTCCGACTCTTTCCTCAGCTTTTGATG ACCCTGCTCATCCAGATTCACCACAGCATCGGCCTCACCATGTCTGACGTCAGCATCCCAAGTGGCCTGT ATGCAGAGCAGGAAGTACCAATGGAGGTTACGCCTTTGTGCTTCGCCATACAAGCTACAAAGACTCTCCT CCTCAGAACCCTGTGCTGGCAGGAGTTCAGCATCATGGAAAAGAGCGGCGGATGGACCCTTCTGAAGGGA GAAGGCCATCTTCAGGGAGTGTTCCTCCTTGCCAATGCCTTGATGGAAAGAAGTCACCTCTTTGCATATA AGATCTTGTACTTGCTGGTCCCTTTGATTAACCGAGGGAATGACAAGCATAAACTCACATCTGCAGGCTT TTTTGTGGAGCTCCTGAAGAGTCCGATGGCCAGGAGACTGCCCAAGGTATACTCTACTATCCGCCTGAAA GCCTGGCTGAATGAAGAGAGTAAGCTCTTCAGGATCCTTGCACTGAGGGGACTGCGAAATCTTGTCAGAC ACCAGGAGATGAGAGAAGACATCAAAAGCCTGCTGCCATGCATCTTAAGTAGCCTACATGAGACCGATGA GAGGATCATTTTGTTGGCTATCCAGATTCTCCTGCAGCTTGTCAGGATGCTAGACTCCACCACCTTGGCT ACCATGATGAAGACCCTGCTTTCCTTATTTGGTGATGTGAGACAGGACGTTCACTGTTTCTCCATGACTC TTTTTGGAGCATCCATAAAGGCTGTGAAACACACAGAGAAGAAGAGCGTGGAAGATCAAGTGCTGGAGAG CTTAGTCCCACTACTTCTGTTTTCTCAGGATGAAAATGATGAAATAGCTAAGGAGAGTAGACGAGTCCTA ACTCTTTGTGCCCGGTTCCTGAATTGGAAGCTGCCCCGAGAAGTATACTGCAAAGATCCCTTATACATCA AACCAAATGAAGTTAGAAGGGTCTGCAAATTCTTTGGAGAAAAAAGCAAGGGGAAGATAGACATCCTCGA CCAAACACTGCCGTATTCCAAGGATCCAAAACTTCCCATCAGAAGAACAGCTGTCTTGTTTGTAGGGCTC TTATCACATTATGTGGATACAAGTGAACTCAAGAGGAAAGGTACTGACTGGATAGAGAAAGATCTGAGAG AACTGTTACAAGACCCCGAGCCCTCTTTGCGCATCCTTGCCTCCCAGGCTCTGTTCCGAATCCAGAGGGT GGGGAGTACATCAGAAGCAGAGACAAGCGTTTCCTGGTTGAGGAAGCTCTTGTGCTGTCTTCATACTTAG
Translation (1049 aa): MPLPRRGGEPRLAGARVVRTSLPRATPRSPKRVGRGAPLLSHAQRLTRRRHSSEQVPPEPEQADFRSGKW LQERAGGDARDPRHTPLARMGSRQRASGTEEVVIPCASDSDSGSVDLQLSNLDDVQKGGASVEFTDSDIA DIPTLPQESLPDNLRLLTLQEPLSETSIERLVQSIQEVLHGELKGETQKLKFLRSLSSLSQTIPYDENTE SFIHRHTAEIVHVLSVLVQEEPLHSLTSMVRQEIFVTITDLSFQNVYLLFGSEDREDLLGLITKSIISLP ATSTPIQLLKIVSNQAIEQECLYRETFEAFSVMLQSLVIKDPHLEFFDSIFKHIDPWLQSDRDHERERAT TVMAQVLKCLSSYLSLKLPLQFQRLGNLVAVMALLCGDPQKEVAEEAAEGTHYLLHITLRLKYIMQDRDN NSKNLRETLKKCRLLLEQYSLKRFYCCPYKIVQVFEVFLDSRELGQFIMTILDSLKNLPHPCIQQTAGEL LITLVKSAEARFERVPEIVGVICARLSIITLTSVRQQIINTVSLFVSRPKYTDVVLSHLLCHPVPYDRHL AELWRSLEVELSNTTWVLWRLLRKLQKCHEGPSQEKMAYVAVAVTDALYEVLMGNKLRAAAFRLFPQLLM TLLIQIHHSIGLTMSDVSIPSGLYAEQEVPMEVTPLCFAIQATKTLLLRTLCWQEFSIMEKSGGWTLLKG EGHLQGVFLLANALMERSHLFAYKILYLLVPLINRGNDKHKLTSAGFFVELLKSPMARRLPKVYSTIRLK AWLNEESKLFRILALRGLRNLVRHQEMREDIKSLLPCILSSLHETDERIILLAIQILLQLVRMLDSTTLA TMMKTLLSLFGDVRQDVHCFSMTLFGASIKAVKHTEKKSVEDQVLESLVPLLLFSQDENDEIAKESRRVL TLCARFLNWKLPREVYCKDPLYIKPNEVRRVCKFFGEKSKGKIDILDQTLPYSKDPKLPIRRTAVLFVGL LSHYVDTSELKRKGTDWIEKDLRELLQDPEPSLRILASQALFRIQRVGSTSEAETSVSWLRKLLCCLHT
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