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Report for CCDS38303.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
38303.2 Public Mus musculus 2 Mroh8 23 108 98 CCDS HistoryNCBI Gene:629499Re-query CCDS DB by CCDS ID:38303.2See the combined annotation on chromosome 2 in Sequence Viewer

Public Note for CCDS 38303.2
The coding region has been updated to extend the N-terminus to one that is more supported by the available transcript and conservation data. The transcript is predicted to be a candidate for nonsense-mediated mRNA decay (NMD), but the protein is represented because the gene is believed to be protein-coding based on good conservation of the CDS, and because all currently available mouse transcripts (AK029507.1, AK132763.1 and BC150937.1) are NMD candidates. Furthermore, the stop codon is only 56 nts from the last splice site, which suggests that the transcript is only marginally an NMD candidate and may escape NMD at least some of the time.

Public since: CCDS release 4, NCBI annotation release 37.1, Ensembl annotation release 47

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
Nonsense-mediated decay (NMD) candidate

Sequence IDs included in CCDS 38303.2

Original Current Source Nucleotide ID Protein ID Status in CCDS Seq. Status Links
Original member Current member EBI ENSMUST00000143663.1 ENSMUSP00000124362.1 Accepted alive Link to Ensembl Transcript Viewer:ENSMUST00000143663.1Link to Ensembl Protein Viewer:ENSMUSP00000124362.1Re-query CCDS DB by Nucleotide ID:ENSMUST00000143663Re-query CCDS DB by Protein ID:ENSMUSP00000124362
Original member Current member NCBI NM_001039557.4 NP_001034646.2 Accepted alive Link to Nucleotide Sequence:NM_001039557.4Link to Protein Sequence:NP_001034646.2Re-query CCDS DB by Nucleotide ID:NM_001039557Re-query CCDS DB by Protein ID:NP_001034646Link to BLAST:NP_001034646.2

Chromosomal Locations for CCDS 38303.2

Assembly GRCm38.p6 (GCF_000001635.26)

On '-' strand of Chromosome 2 (NC_000068.7)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2See the combined annotation on chromosome 2 in Sequence Viewer

Chromosome Start Stop Links
2 157211673 157211821 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157213676 157213741 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157214900 157214999 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157216910 157217032 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157220060 157220215 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157221144 157221308 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157222764 157222904 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157223188 157223302 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157223906 157224040 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157225438 157225628 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157228621 157228756 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157229911 157230071 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157233063 157233215 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157238316 157238437 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157241714 157241849 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157252964 157253068 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157254930 157255025 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157256327 157256471 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157258028 157258107 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157265073 157265195 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157269481 157269626 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157271964 157272085 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 157279192 157279475 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (3150 nt):
ATGCCCCTGCCCCGTAGGGGAGGGGAACCGCGCCTAGCCGGCGCCCGTGTGGTCCGCACTAGCCTCCCGC
GG
GCGACGCCCCGCTCCCCAAAGCGTGTCGGCCGCGGGGCCCCACTATTGAGCCATGCGCAACGCCTCAC
C
CGGCGGCGCCATTCCTCCGAGCAGGTCCCACCGGAGCCCGAGCAGGCAGACTTCCGCTCCGGGAAGTGG
CTC
CAAGAGCGCGCCGGAGGGGACGCCAGGGACCCGCGGCACACGCCACTTGCCAGAATGGGCTCCCGGC
AA
AGGGCCAGCGGTACAGAAGAAGTAGTGATCCCCTGTGCTTCTGACAGTGACTCAGGGAGTGTAGACCT
G
CAGCTGAGCAACTTAGACGACGTTCAAAAGGGTGGAGCTAGTGTTGAATTCACAGATTCGGACATCGCT
GAC
ATCCCTACACTGCCTCAGGAGTCCCTGCCAGATAACCTCAGGTTACTTACTCTCCAGGAGCCCCTCA
GT
GAGACCAGCATTGAGAGACTGGTCCAGTCCATCCAGGAAGTTTTACATGGTGAGCTAAAGGGGGAAAC
T
CAAAAGTTGAAGTTCCTAAGATCTTTGTCTTCTTTGAGCCAAACTATACCTTATGACGAAAACACGGAA
TCA
TTTATTCACCGCCACACAGCAGAAATAGTGCATGTTCTAAGTGTGTTGGTACAGGAGGAGCCTCTGC
AC
TCTCTAACCAGCATGGTGCGCCAGGAGATCTTTGTCACCATCACTGACCTCAGTTTCCAAAATGTGTA
C
CTGTTGTTTGGCTCTGAAGACCGAGAGGACTTGCTTGGGCTTATCACCAAAAGTATAATCTCTCTGCCC
GCC
ACAAGCACCCCTATCCAGCTGCTGAAGATAGTGTCCAACCAGGCCATCGAGCAAGAGTGTCTCTACA
GG
GAGACGTTCGAGGCCTTTTCTGTGATGCTGCAGAGTCTGGTAATAAAAGATCCACATCTGGAATTTTT
T
GACAGCATTTTTAAGCACATAGACCCCTGGTTACAGTCCGACAGAGACCATGAGCGGGAACGGGCTACC
ACT
GTCATGGCCCAAGTTCTCAAATGCTTATCCAGTTATCTCAGCCTGAAGCTTCCACTGCAGTTCCAGA
GG
CTCGGGAATCTCGTGGCTGTGATGGCGCTGCTGTGTGGGGACCCACAGAAAGAGGTGGCTGAGGAGGC
T
GCAGAGGGGACACACTACCTGCTTCATATCACTCTGAGACTGAAATATATCATGCAGGACAGAGACAAC
AAT
AGCAAGAACTTGAGAGAAACTTTGAAAAAATGCAGGTTGCTGCTGGAGCAATATAGCCTCAAACGGT
TC
TACTGCTGTCCCTACAAGATTGTTCAGGTCTTTGAAGTTTTCCTCGACTCTCGGGAGCTCGGCCAGTT
T
ATCATGACGATATTGGACAGCCTGAAAAATCTGCCGCATCCCTGTATCCAGCAGACAGCAGGAGAGTTG
CTG
ATAACCTTGGTGAAGAGTGCAGAGGCTCGGTTTGAGAGGGTGCCAGAAATAGTAGGTGTGATCTGTG
CT
CGGCTGTCGATAATCACCCTGACTAGTGTCCGGCAACAGATCATAAATACTGTGAGTCTGTTTGTCTC
C
AGACCTAAGTACACAGATGTAGTGCTCAGCCACCTTTTATGCCATCCAGTACCGTATGACAGGCATCTG
GCT
GAATTGTGGAGATCCCTGGAGGTAGAGCTGTCCAACACGACCTGGGTCCTATGGAGGCTCCTGCGGA
AG
CTGCAGAAGTGCCACGAGGGGCCCAGCCAGGAGAAGATGGCCTACGTGGCTGTTGCTGTGACCGATGC
C
CTTTATGAGGTGCTCATGGGGAACAAACTCCGAGCAGCCGCATTCCGACTCTTTCCTCAGCTTTTGATG
ACC
CTGCTCATCCAGATTCACCACAGCATCGGCCTCACCATGTCTGACGTCAGCATCCCAAGTGGCCTGT
AT
GCAGAGCAGGAAGTACCAATGGAGGTTACGCCTTTGTGCTTCGCCATACAAGCTACAAAGACTCTCCT
C
CTCAGAACCCTGTGCTGGCAGGAGTTCAGCATCATGGAAAAGAGCGGCGGATGGACCCTTCTGAAGGGA
GAA
GGCCATCTTCAGGGAGTGTTCCTCCTTGCCAATGCCTTGATGGAAAGAAGTCACCTCTTTGCATATA
AG
ATCTTGTACTTGCTGGTCCCTTTGATTAACCGAGGGAATGACAAGCATAAACTCACATCTGCAGGCTT
T
TTTGTGGAGCTCCTGAAGAGTCCGATGGCCAGGAGACTGCCCAAGGTATACTCTACTATCCGCCTGAAA
GCC
TGGCTGAATGAAGAGAGTAAGCTCTTCAGGATCCTTGCACTGAGGGGACTGCGAAATCTTGTCAGAC
AC
CAGGAGATGAGAGAAGACATCAAAAGCCTGCTGCCATGCATCTTAAGTAGCCTACATGAGACCGATGA
G
AGGATCATTTTGTTGGCTATCCAGATTCTCCTGCAGCTTGTCAGGATGCTAGACTCCACCACCTTGGCT
ACC
ATGATGAAGACCCTGCTTTCCTTATTTGGTGATGTGAGACAGGACGTTCACTGTTTCTCCATGACTC
TT
TTTGGAGCATCCATAAAGGCTGTGAAACACACAGAGAAGAAGAGCGTGGAAGATCAAGTGCTGGAGAG
C
TTAGTCCCACTACTTCTGTTTTCTCAGGATGAAAATGATGAAATAGCTAAGGAGAGTAGACGAGTCCTA
ACT
CTTTGTGCCCGGTTCCTGAATTGGAAGCTGCCCCGAGAAGTATACTGCAAAGATCCCTTATACATCA
AA
CCAAATGAAGTTAGAAGGGTCTGCAAATTCTTTGGAGAAAAAAGCAAGGGGAAGATAGACATCCTCGA
C
CAAACACTGCCGTATTCCAAGGATCCAAAACTTCCCATCAGAAGAACAGCTGTCTTGTTTGTAGGGCTC
TTA
TCACATTATGTGGATACAAGTGAACTCAAGAGGAAAGGTACTGACTGGATAGAGAAAGATCTGAGAG
AA
CTGTTACAAGACCCCGAGCCCTCTTTGCGCATCCTTGCCTCCCAGGCTCTGTTCCGAATCCAGAGGGT
G
GGGAGTACATCAGAAGCAGAGACAAGCGTTTCCTGGTTGAGGAAGCTCTTGTGCTGTCTTCATACTTAG


Translation (1049 aa):
MPLPRRGGEPRLAGARVVRTSLPRATPRSPKRVGRGAPLLSHAQRLTRRRHSSEQVPPEPEQADFRSGKW
L
QERAGGDARDPRHTPLARMGSRQ
RASGTEEVVIPCASDSDSGSVDLQLSNLDDVQKGGASVEFTDSDIA
D
IPTLPQESLPDNLRLLTLQEPLSETSIERLVQSIQEVLHGELK
GETQKLKFLRSLSSLSQTIPYDENTE
S
FIHRHTAEIVHVLS
VLVQEEPLHSLTSMVRQEIFVTITDLSFQNVYLLFGSEDREDLLGLITKSIISLP
A
TSTPIQLLKIVSNQAIEQE
CLYRETFEAFSVMLQSLVIKDPHLEFFDSIFKHIDPWLQSDRDHERERAT
T
VMAQVLKCLSSYLSLK
LPLQFQRLGNLVAVMALLCGDPQKEVAEEAAEGTHYLLHITLRLKYIMQDRDN
N
SKNLRETLKKCRLLLEQYSLKRFYCCPYKIVQ
VFEVFLDSRELGQFIMTILDSLKNLPHPCIQQTAGEL
L
ITLVKSAEARFER
VPEIVGVICARLSIITLTSVRQQIINTVSLFVSRPKYTDVVLSHLLCHPVPYDRHL
A
ELWRSLEVELSNTTWVLWRLLRKLQKCHEGPSQEKMAYVAVA
VTDALYEVLMGNKLRAAAFRLFPQLLM
T
LLIQIHHSIGLTMSDVSIPSGLYAEQEVPMEVTPL
CFAIQATKTLLLRTLCWQEFSIMEKSGGWTLLKG
E
GHLQGVFLLA
NALMERSHLFAYKILYLLVPLINRGNDKHKLTSAGFFVELLKSPMARRLPKVYSTIRLK
A
WLNEESKLFRILALRGLRNLVRHQEM
REDIKSLLPCILSSLHETDERIILLAIQILLQLVRMLDSTTLA
T
MMKTLLSLFGD
VRQDVHCFSMTLFGASIKAVKHTEKKSVEDQVLESLVPLLLFSQDENDEIAKESRRVL
T
LCARFLNWKLPREVYCKDPLYIKPNEVRRVCKFF
GEKSKGKIDILDQTLPYSKDPKLPIRRTAVLFVGL
L
SHYVDTSELKRKGTDWIEK
DLRELLQDPEPSLRILASQALFRIQRVGSTSEAETSVSWLRKLLCCLHT



Links Key
 Links to:   History report
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 Re-query CCDS DB by:   CCDS ID
  Gene ID
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 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
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