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Conserved domains on  [gi|34148711|gb|AAQ62842|]
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melanoma chondroitin sulfate proteoglycan [Homo sapiens]

Protein Classification

laminin G domain-containing protein( domain architecture ID 11516022)

laminin G (lLamG) domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
1456-1563 2.41e-44

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 156.61  E-value: 2.41e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1456 QSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQ-PSNGRVVLRGAPGTEVRSF 1534
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQgPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1535 TQAQLDGGLVLFSHRG--TLDGGFRFRLSDG 1563
Cdd:pfam16184   81 TQADIDSGLVVYVHDGseSTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-645 4.71e-31

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 118.86  E-value: 4.71e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    536 RGQTYLLPIQVNPVNDPPHIIFPHGSLMViLEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATE 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRL-WEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|..
gi 34148711    616 FSCRELEAGSLVYVHRGGPAQD--LTFRVSDG 645
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSdgFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1815-1924 8.76e-30

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 115.01  E-value: 8.76e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1815 PQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRF 1894
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1895 TQADVDSGRLAFVANGS-SVAGIFQLSMSDG 1924
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSeSTSDGFTFQVTDG 111
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 203-361 1.11e-23

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


:

Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 99.41  E-value: 1.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  203 ALGFSGPhSLAAFPAWGTQ-DEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVAD 281
Cdd:cd00110    1 GVSFSGS-SYVRLPTLPAPrTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLND 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  282 GQPHEVSVHINAHRLEISVDQYP--THTSNRGvLSYLEPRGSLLLGGLDAEasrhlqehrLGLTPEATNASLLGCMEDLS 359
Cdd:cd00110   80 GQWHSVSVERNGRSVTLSVDGERvvESGSPGG-SALLNLDGPLYLGGLPED---------LKSPGLPVSPGFVGCIRDLK 149


                 ..
gi 34148711  360 VN 361
Cdd:cd00110  150 VN 151
Cadherin_3 pfam16184
Cadherin-like;
1003-1110 1.06e-21

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 92.28  E-value: 1.06e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1003 VRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSgfADAQLVLT-RKDLLFGSIVAVDEPTRPIYRF 1081
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDT--PPEDLTYTvVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1082 TQEDLRKRRVLFVHSGAD--RGWIQLQVSDG 1110
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSEstSDGFTFQVTDG 111
Cadherin_3 super family cl28802
Cadherin-like;
1225-1336 2.45e-16

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 76.87  E-value: 2.45e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1225 TLQVTIaleGP---LAPlKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALadepps 1301
Cdd:pfam16184    6 TFNITI---IPvndEAP-VLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL------ 75

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 34148711   1302 ldPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDV 1336
Cdd:pfam16184   76 --PVTNFTQADIDSGLVVYVHDGSESTSDGFTFQV 108
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 29-176 4.31e-16

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


:

Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 77.46  E-value: 4.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   29 AASFFGENHLEVPV-ATALTDIDLQLQFSTSQPEAL--LLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPaeTLLS 105
Cdd:cd00110    1 GVSFSGSSYVRLPTlPAPRTRLSISFSFRTTSPNGLllYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSK--TPLN 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 34148711  106 DSIPHTVVLTVVEGWATLSVDG--FLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLN 176
Cdd:cd00110   79 DGQWHSVSVERNGRSVTLSVDGerVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
Cadherin_3 super family cl28802
Cadherin-like;
884-989 5.45e-14

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.94  E-value: 5.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    884 SPLYTFPIHIGG-DPDAPVLT-NVLLVVPEGGEGVLSADHLFVKSLNSA-SYL-YEVMERPRHGRLAWRGtqDKTTMVTS 959
Cdd:pfam16184    2 SVPFTFNITIIPvNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLtYTVVQGPSHGHLALKG--APGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|
gi 34148711    960 FTNEDLLRGRLVYQHDDSETTEDDIPFVAT 989
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
Cadherin_3 super family cl28802
Cadherin-like;
1710-1802 4.07e-13

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 67.63  E-value: 4.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1710 NKGLWVPEGQRARITVAALDASNLlASVPspqrseHDVLFQVTQFPSRGQLLVSEEPlHAGQPHFLQSQLAAGQLVYAHG 1789
Cdd:pfam16184   24 NTGLRLWEGSSRPITPDLLQAEDP-DTPP------EDLTYTVVQGPSHGHLALKGAP-GLPVTNFTQADIDSGLVVYVHD 95

                           90
                   ....*....|...
gi 34148711   1790 GGGTQQDGFHFRA 1802
Cdd:pfam16184   96 GSESTSDGFTFQV 108
Cadherin_3 super family cl28802
Cadherin-like;
1128-1215 6.57e-11

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 61.46  E-value: 6.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1128 RVANGSSLVVPQGGQGTIDTAVLHLdTNLDIrSGDEVHYHVTAGPRWGQLVRAGQP---ATAFSQQDLLDGAVLYSHNGS 1204
Cdd:pfam16184   20 VLTTNTGLRLWEGSSRPITPDLLQA-EDPDT-PPEDLTYTVVQGPSHGHLALKGAPglpVTNFTQADIDSGLVVYVHDGS 97

                           90
                   ....*....|.
gi 34148711   1205 LSPRDTMAFSV 1215
Cdd:pfam16184   98 ESTSDGFTFQV 108
Cadherin_3 super family cl28802
Cadherin-like;
790-878 5.01e-07

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 50.29  E-value: 5.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    790 EPLHTQNTQQETLTTAHLEATLEEagpSPPTF-HYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYgaTARASEA 868
Cdd:pfam16184   25 TGLRLWEGSSRPITPDLLQAEDPD---TPPEDlTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVY--VHDGSES 99

                           90
                   ....*....|
gi 34148711    869 VEDTFRFRVT 878
Cdd:pfam16184  100 TSDGFTFQVT 109
Cadherin_3 super family cl28802
Cadherin-like;
436-523 1.55e-06

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    436 PLVVAEGGTAWLEWRHVQpTLDLMEAelrKSQVLFSVTRGARHGELEL-DIPGAQARKmFTLLDVVNRKARFIHDGSEDT 514
Cdd:pfam16184   26 GLRLWEGSSRPITPDLLQ-AEDPDTP---PEDLTYTVVQGPSHGHLALkGAPGLPVTN-FTQADIDSGLVVYVHDGSEST 100


                   ....*....
gi 34148711    515 SDQLVLEVS 523
Cdd:pfam16184  101 SDGFTFQVT 109
Cadherin_3 super family cl28802
Cadherin-like;
1365-1446 1.88e-06

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1365 FSVPEGGSLTLAPPLLRVSGPyfPTLL-GLSLQVLEPPQHGALQKEDGPQaRTLSAFSWRMVEEQLIRYVHDGSETLTDS 1443
Cdd:pfam16184   27 LRLWEGSSRPITPDLLQAEDP--DTPPeDLTYTVVQGPSHGHLALKGAPG-LPVTNFTQADIDSGLVVYVHDGSESTSDG 103


                   ...
gi 34148711   1444 FVL 1446
Cdd:pfam16184  104 FTF 106
Cadherin_3 super family cl28802
Cadherin-like;
2041-2123 2.64e-03

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 39.51  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   2041 VTVRALLHVWaggpwpQGATLRLDPTVLDAGELANRTGSVpRFRLLEGPRHGRVVRvpraRTEPGgsQLVEQFTQQDLED 2120
Cdd:pfam16184   21 LTTNTGLRLW------EGSSRPITPDLLQAEDPDTPPEDL-TYTVVQGPSHGHLAL----KGAPG--LPVTNFTQADIDS 87


                   ...
gi 34148711   2121 GRL 2123
Cdd:pfam16184   88 GLV 90
 
Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
1456-1563 2.41e-44

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 156.61  E-value: 2.41e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1456 QSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQ-PSNGRVVLRGAPGTEVRSF 1534
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQgPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1535 TQAQLDGGLVLFSHRG--TLDGGFRFRLSDG 1563
Cdd:pfam16184   81 TQADIDSGLVVYVHDGseSTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-645 4.71e-31

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 118.86  E-value: 4.71e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    536 RGQTYLLPIQVNPVNDPPHIIFPHGSLMViLEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATE 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRL-WEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|..
gi 34148711    616 FSCRELEAGSLVYVHRGGPAQD--LTFRVSDG 645
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSdgFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1815-1924 8.76e-30

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 115.01  E-value: 8.76e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1815 PQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRF 1894
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1895 TQADVDSGRLAFVANGS-SVAGIFQLSMSDG 1924
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSeSTSDGFTFQVTDG 111
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 203-361 1.11e-23

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 99.41  E-value: 1.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  203 ALGFSGPhSLAAFPAWGTQ-DEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVAD 281
Cdd:cd00110    1 GVSFSGS-SYVRLPTLPAPrTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLND 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  282 GQPHEVSVHINAHRLEISVDQYP--THTSNRGvLSYLEPRGSLLLGGLDAEasrhlqehrLGLTPEATNASLLGCMEDLS 359
Cdd:cd00110   80 GQWHSVSVERNGRSVTLSVDGERvvESGSPGG-SALLNLDGPLYLGGLPED---------LKSPGLPVSPGFVGCIRDLK 149


                 ..
gi 34148711  360 VN 361
Cdd:cd00110  150 VN 151
Cadherin_3 pfam16184
Cadherin-like;
1003-1110 1.06e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 92.28  E-value: 1.06e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1003 VRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSgfADAQLVLT-RKDLLFGSIVAVDEPTRPIYRF 1081
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDT--PPEDLTYTvVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1082 TQEDLRKRRVLFVHSGAD--RGWIQLQVSDG 1110
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSEstSDGFTFQVTDG 111
LamG smart00282
Laminin G domain;
225-363 1.44e-21

Laminin G domain;


Pssm-ID: 214598 [Multi-domain]  Cd Length: 132  Bit Score: 92.40  E-value: 1.44e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711     225 TLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTV-LLHNSVPVADGQPHEVSVHINAHRLEISVDQY 303
Cdd:smart00282    1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPArLTSDPTPLNDGQWHRVAVERNGRSVTLSVDGG 80

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 34148711     304 -PTHTSNRGVLSYLEPRGSLLLGGLDAEASRhlqehrlglTPEATNASLLGCMEDLSVNGQ 363
Cdd:smart00282   81 nRVSGESPGGLTILNLDGPLYLGGLPEDLKL---------PPLPVTPGFRGCIRNLKVNGK 132
Laminin_G_2 pfam02210
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ...
 232-363 2.01e-20

Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.


Pssm-ID: 460494 [Multi-domain]  Cd Length: 126  Bit Score: 89.02  E-value: 2.01e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    232 TQSRQAPLaFQAGGRRGDFIYVDIFEGHLRAVVEKGQG-TVLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNR 310
Cdd:pfam02210    3 TRQPNGLL-LYAGGGGSDFLALELVNGRLVLRYDLGSGpESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSSLP 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 34148711    311 -GVLSYLEPRGSLLLGGLDaeasrhlqeHRLGLTPEATNASLLGCMEDLSVNGQ 363
Cdd:pfam02210   82 pGESLLLNLNGPLYLGGLP---------PLLLLPALPVRAGFVGCIRDVRVNGE 126
Cadherin_3 pfam16184
Cadherin-like;
1225-1336 2.45e-16

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 76.87  E-value: 2.45e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1225 TLQVTIaleGP---LAPlKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALadepps 1301
Cdd:pfam16184    6 TFNITI---IPvndEAP-VLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL------ 75

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 34148711   1302 ldPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDV 1336
Cdd:pfam16184   76 --PVTNFTQADIDSGLVVYVHDGSESTSDGFTFQV 108
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 29-176 4.31e-16

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 77.46  E-value: 4.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   29 AASFFGENHLEVPV-ATALTDIDLQLQFSTSQPEAL--LLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPaeTLLS 105
Cdd:cd00110    1 GVSFSGSSYVRLPTlPAPRTRLSISFSFRTTSPNGLllYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSK--TPLN 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 34148711  106 DSIPHTVVLTVVEGWATLSVDG--FLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLN 176
Cdd:cd00110   79 DGQWHSVSVERNGRSVTLSVDGerVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
Laminin_G_1 pfam00054
Laminin G domain;
70-181 1.93e-15

Laminin G domain;


Pssm-ID: 395008 [Multi-domain]  Cd Length: 131  Bit Score: 75.05  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711     70 PADHLLLQLYSGRLQVRLVLGQEELRlqTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAP---LEVPYGL 146
Cdd:pfam00054   18 ERDFLALELRDGRLEVSYDLGSGAAV--VRSGDKLNDGKWHSVELERNGRSGTLSVDGEARPTGESPLGAttdLDVDGPL 95

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 34148711    147 FVGGTGTLGLPYLRGTSRP-LRGCLHAATLNGRSLL 181
Cdd:pfam00054   96 YVGGLPSLGVKKRRLAISPsFDGCIRDVIVNGKPLD 131
LamG smart00282
Laminin G domain;
50-178 3.89e-14

Laminin G domain;


Pssm-ID: 214598 [Multi-domain]  Cd Length: 132  Bit Score: 71.22  E-value: 3.89e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711      50 DLQLQFSTSQPEAL--LLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPAETLlSDSIPHTVVLTVVEGWATLSVDG 127
Cdd:smart00282    1 SISFSFRTTSPNGLllYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPL-NDGQWHRVAVERNGRSVTLSVDG 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|...
gi 34148711     128 FLNASSAVPGAP--LEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGR 178
Cdd:smart00282   80 GNRVSGESPGGLtiLNLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
Cadherin_3 pfam16184
Cadherin-like;
884-989 5.45e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.94  E-value: 5.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    884 SPLYTFPIHIGG-DPDAPVLT-NVLLVVPEGGEGVLSADHLFVKSLNSA-SYL-YEVMERPRHGRLAWRGtqDKTTMVTS 959
Cdd:pfam16184    2 SVPFTFNITIIPvNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLtYTVVQGPSHGHLALKG--APGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|
gi 34148711    960 FTNEDLLRGRLVYQHDDSETTEDDIPFVAT 989
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
1710-1802 4.07e-13

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 67.63  E-value: 4.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1710 NKGLWVPEGQRARITVAALDASNLlASVPspqrseHDVLFQVTQFPSRGQLLVSEEPlHAGQPHFLQSQLAAGQLVYAHG 1789
Cdd:pfam16184   24 NTGLRLWEGSSRPITPDLLQAEDP-DTPP------EDLTYTVVQGPSHGHLALKGAP-GLPVTNFTQADIDSGLVVYVHD 95

                           90
                   ....*....|...
gi 34148711   1790 GGGTQQDGFHFRA 1802
Cdd:pfam16184   96 GSESTSDGFTFQV 108
Cadherin_3 pfam16184
Cadherin-like;
1128-1215 6.57e-11

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 61.46  E-value: 6.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1128 RVANGSSLVVPQGGQGTIDTAVLHLdTNLDIrSGDEVHYHVTAGPRWGQLVRAGQP---ATAFSQQDLLDGAVLYSHNGS 1204
Cdd:pfam16184   20 VLTTNTGLRLWEGSSRPITPDLLQA-EDPDT-PPEDLTYTVVQGPSHGHLALKGAPglpVTNFTQADIDSGLVVYVHDGS 97

                           90
                   ....*....|.
gi 34148711   1205 LSPRDTMAFSV 1215
Cdd:pfam16184   98 ESTSDGFTFQV 108
Cadherin_3 pfam16184
Cadherin-like;
790-878 5.01e-07

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 50.29  E-value: 5.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    790 EPLHTQNTQQETLTTAHLEATLEEagpSPPTF-HYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYgaTARASEA 868
Cdd:pfam16184   25 TGLRLWEGSSRPITPDLLQAEDPD---TPPEDlTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVY--VHDGSES 99

                           90
                   ....*....|
gi 34148711    869 VEDTFRFRVT 878
Cdd:pfam16184  100 TSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
436-523 1.55e-06

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    436 PLVVAEGGTAWLEWRHVQpTLDLMEAelrKSQVLFSVTRGARHGELEL-DIPGAQARKmFTLLDVVNRKARFIHDGSEDT 514
Cdd:pfam16184   26 GLRLWEGSSRPITPDLLQ-AEDPDTP---PEDLTYTVVQGPSHGHLALkGAPGLPVTN-FTQADIDSGLVVYVHDGSEST 100


                   ....*....
gi 34148711    515 SDQLVLEVS 523
Cdd:pfam16184  101 SDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
1365-1446 1.88e-06

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1365 FSVPEGGSLTLAPPLLRVSGPyfPTLL-GLSLQVLEPPQHGALQKEDGPQaRTLSAFSWRMVEEQLIRYVHDGSETLTDS 1443
Cdd:pfam16184   27 LRLWEGSSRPITPDLLQAEDP--DTPPeDLTYTVVQGPSHGHLALKGAPG-LPVTNFTQADIDSGLVVYVHDGSESTSDG 103


                   ...
gi 34148711   1444 FVL 1446
Cdd:pfam16184  104 FTF 106
Cadherin_3 pfam16184
Cadherin-like;
2041-2123 2.64e-03

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 39.51  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   2041 VTVRALLHVWaggpwpQGATLRLDPTVLDAGELANRTGSVpRFRLLEGPRHGRVVRvpraRTEPGgsQLVEQFTQQDLED 2120
Cdd:pfam16184   21 LTTNTGLRLW------EGSSRPITPDLLQAEDPDTPPEDL-TYTVVQGPSHGHLAL----KGAPG--LPVTNFTQADIDS 87


                   ...
gi 34148711   2121 GRL 2123
Cdd:pfam16184   88 GLV 90
 
Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
1456-1563 2.41e-44

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 156.61  E-value: 2.41e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1456 QSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQ-PSNGRVVLRGAPGTEVRSF 1534
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQgPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1535 TQAQLDGGLVLFSHRG--TLDGGFRFRLSDG 1563
Cdd:pfam16184   81 TQADIDSGLVVYVHDGseSTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-645 4.71e-31

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 118.86  E-value: 4.71e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    536 RGQTYLLPIQVNPVNDPPHIIFPHGSLMViLEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATE 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRL-WEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|..
gi 34148711    616 FSCRELEAGSLVYVHRGGPAQD--LTFRVSDG 645
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSdgFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1815-1924 8.76e-30

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 115.01  E-value: 8.76e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1815 PQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRF 1894
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1895 TQADVDSGRLAFVANGS-SVAGIFQLSMSDG 1924
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSeSTSDGFTFQVTDG 111
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 203-361 1.11e-23

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 99.41  E-value: 1.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  203 ALGFSGPhSLAAFPAWGTQ-DEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVAD 281
Cdd:cd00110    1 GVSFSGS-SYVRLPTLPAPrTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSKTPLND 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711  282 GQPHEVSVHINAHRLEISVDQYP--THTSNRGvLSYLEPRGSLLLGGLDAEasrhlqehrLGLTPEATNASLLGCMEDLS 359
Cdd:cd00110   80 GQWHSVSVERNGRSVTLSVDGERvvESGSPGG-SALLNLDGPLYLGGLPED---------LKSPGLPVSPGFVGCIRDLK 149


                 ..
gi 34148711  360 VN 361
Cdd:cd00110  150 VN 151
Cadherin_3 pfam16184
Cadherin-like;
1003-1110 1.06e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 92.28  E-value: 1.06e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1003 VRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSgfADAQLVLT-RKDLLFGSIVAVDEPTRPIYRF 1081
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDT--PPEDLTYTvVQGPSHGHLALKGAPGLPVTNF 80

                           90       100       110
                   ....*....|....*....|....*....|.
gi 34148711   1082 TQEDLRKRRVLFVHSGAD--RGWIQLQVSDG 1110
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSEstSDGFTFQVTDG 111
LamG smart00282
Laminin G domain;
225-363 1.44e-21

Laminin G domain;


Pssm-ID: 214598 [Multi-domain]  Cd Length: 132  Bit Score: 92.40  E-value: 1.44e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711     225 TLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTV-LLHNSVPVADGQPHEVSVHINAHRLEISVDQY 303
Cdd:smart00282    1 SISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPArLTSDPTPLNDGQWHRVAVERNGRSVTLSVDGG 80

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 34148711     304 -PTHTSNRGVLSYLEPRGSLLLGGLDAEASRhlqehrlglTPEATNASLLGCMEDLSVNGQ 363
Cdd:smart00282   81 nRVSGESPGGLTILNLDGPLYLGGLPEDLKL---------PPLPVTPGFRGCIRNLKVNGK 132
Laminin_G_2 pfam02210
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ...
 232-363 2.01e-20

Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.


Pssm-ID: 460494 [Multi-domain]  Cd Length: 126  Bit Score: 89.02  E-value: 2.01e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    232 TQSRQAPLaFQAGGRRGDFIYVDIFEGHLRAVVEKGQG-TVLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNR 310
Cdd:pfam02210    3 TRQPNGLL-LYAGGGGSDFLALELVNGRLVLRYDLGSGpESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSSLP 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 34148711    311 -GVLSYLEPRGSLLLGGLDaeasrhlqeHRLGLTPEATNASLLGCMEDLSVNGQ 363
Cdd:pfam02210   82 pGESLLLNLNGPLYLGGLP---------PLLLLPALPVRAGFVGCIRDVRVNGE 126
Cadherin_3 pfam16184
Cadherin-like;
1225-1336 2.45e-16

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 76.87  E-value: 2.45e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1225 TLQVTIaleGP---LAPlKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALadepps 1301
Cdd:pfam16184    6 TFNITI---IPvndEAP-VLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL------ 75

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 34148711   1302 ldPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDV 1336
Cdd:pfam16184   76 --PVTNFTQADIDSGLVVYVHDGSESTSDGFTFQV 108
LamG cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 29-176 4.31e-16

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


Pssm-ID: 238058 [Multi-domain]  Cd Length: 151  Bit Score: 77.46  E-value: 4.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   29 AASFFGENHLEVPV-ATALTDIDLQLQFSTSQPEAL--LLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPaeTLLS 105
Cdd:cd00110    1 GVSFSGSSYVRLPTlPAPRTRLSISFSFRTTSPNGLllYAGSQNGGDFLALELEDGRLVLRYDLGSGSLVLSSK--TPLN 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 34148711  106 DSIPHTVVLTVVEGWATLSVDG--FLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLN 176
Cdd:cd00110   79 DGQWHSVSVERNGRSVTLSVDGerVVESGSPGGSALLNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
Laminin_G_1 pfam00054
Laminin G domain;
70-181 1.93e-15

Laminin G domain;


Pssm-ID: 395008 [Multi-domain]  Cd Length: 131  Bit Score: 75.05  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711     70 PADHLLLQLYSGRLQVRLVLGQEELRlqTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAP---LEVPYGL 146
Cdd:pfam00054   18 ERDFLALELRDGRLEVSYDLGSGAAV--VRSGDKLNDGKWHSVELERNGRSGTLSVDGEARPTGESPLGAttdLDVDGPL 95

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 34148711    147 FVGGTGTLGLPYLRGTSRP-LRGCLHAATLNGRSLL 181
Cdd:pfam00054   96 YVGGLPSLGVKKRRLAISPsFDGCIRDVIVNGKPLD 131
Laminin_G_2 pfam02210
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ...
 69-178 2.35e-15

Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.


Pssm-ID: 460494 [Multi-domain]  Cd Length: 126  Bit Score: 74.38  E-value: 2.35e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711     69 GPADHLLLQLYSGRLQVRLVLGQEELRLqTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAP--LEVPYGL 146
Cdd:pfam02210   16 GGSDFLALELVNGRLVLRYDLGSGPESL-LSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSSLPPGESllLNLNGPL 94

                           90       100       110
                   ....*....|....*....|....*....|..
gi 34148711    147 FVGGTGTLGLPYLRGTSRPLRGCLHAATLNGR 178
Cdd:pfam02210   95 YLGGLPPLLLLPALPVRAGFVGCIRDVRVNGE 126
LamG smart00282
Laminin G domain;
50-178 3.89e-14

Laminin G domain;


Pssm-ID: 214598 [Multi-domain]  Cd Length: 132  Bit Score: 71.22  E-value: 3.89e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711      50 DLQLQFSTSQPEAL--LLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPAETLlSDSIPHTVVLTVVEGWATLSVDG 127
Cdd:smart00282    1 SISFSFRTTSPNGLllYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPL-NDGQWHRVAVERNGRSVTLSVDG 79

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|...
gi 34148711     128 FLNASSAVPGAP--LEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGR 178
Cdd:smart00282   80 GNRVSGESPGGLtiLNLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
Cadherin_3 pfam16184
Cadherin-like;
884-989 5.45e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.94  E-value: 5.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    884 SPLYTFPIHIGG-DPDAPVLT-NVLLVVPEGGEGVLSADHLFVKSLNSA-SYL-YEVMERPRHGRLAWRGtqDKTTMVTS 959
Cdd:pfam16184    2 SVPFTFNITIIPvNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLtYTVVQGPSHGHLALKG--APGLPVTN 79

                           90       100       110
                   ....*....|....*....|....*....|
gi 34148711    960 FTNEDLLRGRLVYQHDDSETTEDDIPFVAT 989
Cdd:pfam16184   80 FTQADIDSGLVVYVHDGSESTSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
1710-1802 4.07e-13

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 67.63  E-value: 4.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1710 NKGLWVPEGQRARITVAALDASNLlASVPspqrseHDVLFQVTQFPSRGQLLVSEEPlHAGQPHFLQSQLAAGQLVYAHG 1789
Cdd:pfam16184   24 NTGLRLWEGSSRPITPDLLQAEDP-DTPP------EDLTYTVVQGPSHGHLALKGAP-GLPVTNFTQADIDSGLVVYVHD 95

                           90
                   ....*....|...
gi 34148711   1790 GGGTQQDGFHFRA 1802
Cdd:pfam16184   96 GSESTSDGFTFQV 108
Cadherin_3 pfam16184
Cadherin-like;
1128-1215 6.57e-11

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 61.46  E-value: 6.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1128 RVANGSSLVVPQGGQGTIDTAVLHLdTNLDIrSGDEVHYHVTAGPRWGQLVRAGQP---ATAFSQQDLLDGAVLYSHNGS 1204
Cdd:pfam16184   20 VLTTNTGLRLWEGSSRPITPDLLQA-EDPDT-PPEDLTYTVVQGPSHGHLALKGAPglpVTNFTQADIDSGLVVYVHDGS 97

                           90
                   ....*....|.
gi 34148711   1205 LSPRDTMAFSV 1215
Cdd:pfam16184   98 ESTSDGFTFQV 108
Laminin_G_1 pfam00054
Laminin G domain;
243-363 3.99e-09

Laminin G domain;


Pssm-ID: 395008 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 3.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    243 AGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVADGQPHEVSVHINAHRLEISVD--QYPTHTSNRGVLSYLEPRG 320
Cdd:pfam00054   14 GTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKLNDGKWHSVELERNGRSGTLSVDgeARPTGESPLGATTDLDVDG 93

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 34148711    321 SLLLGGLDAEAsrhLQEHRLGLTPeatnaSLLGCMEDLSVNGQ 363
Cdd:pfam00054   94 PLYVGGLPSLG---VKKRRLAISP-----SFDGCIRDVIVNGK 128
Cadherin_3 pfam16184
Cadherin-like;
790-878 5.01e-07

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 50.29  E-value: 5.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    790 EPLHTQNTQQETLTTAHLEATLEEagpSPPTF-HYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYgaTARASEA 868
Cdd:pfam16184   25 TGLRLWEGSSRPITPDLLQAEDPD---TPPEDlTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVY--VHDGSES 99

                           90
                   ....*....|
gi 34148711    869 VEDTFRFRVT 878
Cdd:pfam16184  100 TSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
436-523 1.55e-06

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711    436 PLVVAEGGTAWLEWRHVQpTLDLMEAelrKSQVLFSVTRGARHGELEL-DIPGAQARKmFTLLDVVNRKARFIHDGSEDT 514
Cdd:pfam16184   26 GLRLWEGSSRPITPDLLQ-AEDPDTP---PEDLTYTVVQGPSHGHLALkGAPGLPVTN-FTQADIDSGLVVYVHDGSEST 100


                   ....*....
gi 34148711    515 SDQLVLEVS 523
Cdd:pfam16184  101 SDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
1365-1446 1.88e-06

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 48.75  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   1365 FSVPEGGSLTLAPPLLRVSGPyfPTLL-GLSLQVLEPPQHGALQKEDGPQaRTLSAFSWRMVEEQLIRYVHDGSETLTDS 1443
Cdd:pfam16184   27 LRLWEGSSRPITPDLLQAEDP--DTPPeDLTYTVVQGPSHGHLALKGAPG-LPVTNFTQADIDSGLVVYVHDGSESTSDG 103


                   ...
gi 34148711   1444 FVL 1446
Cdd:pfam16184  104 FTF 106
Cadherin_3 pfam16184
Cadherin-like;
2041-2123 2.64e-03

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 39.51  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34148711   2041 VTVRALLHVWaggpwpQGATLRLDPTVLDAGELANRTGSVpRFRLLEGPRHGRVVRvpraRTEPGgsQLVEQFTQQDLED 2120
Cdd:pfam16184   21 LTTNTGLRLW------EGSSRPITPDLLQAEDPDTPPEDL-TYTVVQGPSHGHLAL----KGAPG--LPVTNFTQADIDS 87


                   ...
gi 34148711   2121 GRL 2123
Cdd:pfam16184   88 GLV 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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