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Conserved domains on  [gi|973583869|gb|ALX38041|]
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transmembrane protease serine 3, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRCR_2 super family cl02509
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ...
 4-37 1.11e-09

Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.


The actual alignment was detected with superfamily member pfam15494:

Pssm-ID: 470597  Cd Length: 99  Bit Score: 48.10  E-value: 1.11e-09
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 973583869   4 GQNAVLQVFTAAL--WKTMCSDDWKGHYANVACAQL 37
Cdd:pfam15494  1 GENFLLQVYSSARpsWLPVCSDDWNPAYGRAACQQL 36
 
Name Accession Description Interval E-value
SRCR_2 pfam15494
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ...
 4-37 1.11e-09

Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.


Pssm-ID: 464747  Cd Length: 99  Bit Score: 48.10  E-value: 1.11e-09
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 973583869   4 GQNAVLQVFTAAL--WKTMCSDDWKGHYANVACAQL 37
Cdd:pfam15494  1 GENFLLQVYSSARpsWLPVCSDDWNPAYGRAACQQL 36
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 2-37 1.49e-04

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 35.01  E-value: 1.49e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 973583869     2 VGGQNA---VLQVFTAALWKTMCSDDWKGHYANVACAQL 37
Cdd:smart00202   4 VGGGSPcegRVEVYHNGQWGTVCDDGWDLRDANVVCRQL 42
 
Name Accession Description Interval E-value
SRCR_2 pfam15494
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ...
 4-37 1.11e-09

Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.


Pssm-ID: 464747  Cd Length: 99  Bit Score: 48.10  E-value: 1.11e-09
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 973583869   4 GQNAVLQVFTAAL--WKTMCSDDWKGHYANVACAQL 37
Cdd:pfam15494  1 GENFLLQVYSSARpsWLPVCSDDWNPAYGRAACQQL 36
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 2-37 1.49e-04

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 35.01  E-value: 1.49e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 973583869     2 VGGQNA---VLQVFTAALWKTMCSDDWKGHYANVACAQL 37
Cdd:smart00202   4 VGGGSPcegRVEVYHNGQWGTVCDDGWDLRDANVVCRQL 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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