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Conserved domains on  [gi|484854295|gb|EOB12528|]
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50S ribosomal protein L24P [Nosema bombycis CQ1]

Protein Classification

uL24 family ribosomal protein( domain architecture ID 11246010)

uL24 family ribosomal protein is required for the assembly of different ribosomal subunits and are widely distributed among all living organisms.

Gene Ontology:  GO:0006412|GO:0003735|GO:0003723
PubMed:  24524803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 9-123 3.20e-37

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


:

Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 123.00  E-value: 3.20e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295    9 SPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGCIeT 88
Cdd:pfam16906   1 SSSRRKQRKAHFNAPSHIRRKLMSAPLSKELREKYGVRSLPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGVT-R 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484854295   89 GEKEEETKNALIHPSSVTIVKFSMEDGREEKLEKR 123
Cdd:pfam16906  80 EKANGTTVPVPIHPSKVVITKLKLDKDRKKILERK 114
 
Name Accession Description Interval E-value
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 9-123 3.20e-37

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 123.00  E-value: 3.20e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295    9 SPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGCIeT 88
Cdd:pfam16906   1 SSSRRKQRKAHFNAPSHIRRKLMSAPLSKELREKYGVRSLPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGVT-R 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484854295   89 GEKEEETKNALIHPSSVTIVKFSMEDGREEKLEKR 123
Cdd:pfam16906  80 EKANGTTVPVPIHPSKVVITKLKLDKDRKKILERK 114
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 9-123 1.08e-21

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 83.36  E-value: 1.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295    9 SPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGcIET 88
Cdd:TIGR01080   1 SKQPRKQRKALFTAPLHERRKLMSAPLSKELREKYGKRALPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEG-VTK 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484854295   89 GEKEEETKNALIHPSSVTIVKFSMEDGREEKLEKR 123
Cdd:TIGR01080  80 EKVDGTEVPVPLHPSNVMITKLHLDDEKRKKLLER 114
PTZ00194 PTZ00194
60S ribosomal protein L26; Provisional
 6-133 1.14e-21

60S ribosomal protein L26; Provisional


Pssm-ID: 185508  Cd Length: 143  Bit Score: 84.03  E-value: 1.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295   6 KTKSPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGc 85
Cdd:PTZ00194   3 SIVSSSRRKARKAHFTAPSHLRRKLMSAPLSKELRAKYNVRSMPVRKDDEVMVVRGHHKGREGKVTAVYRKKWVIHIEK- 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 484854295  86 IETGEKEEETKNALIHPSSVTIVKFSMEDGREEKLEkRKNAREETLRR 133
Cdd:PTZ00194  82 ITREKANGEPVQIGIHPSNVIITKLKLNKDRKAILE-RKARSTKSDKG 128
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 54-107 8.58e-10

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 51.36  E-value: 8.58e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 484854295  54 DIVKVHSGPYKGKEGQVLEVIPKEYRITVEGC----------IETGEKEEETKNALIHPSSVTI 107
Cdd:cd06089    2 DEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVnvvkkhvkpsQENPQGGIIEVEAPIHISNVML 65
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 54-84 1.67e-06

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 43.51  E-value: 1.67e-06
                         10        20        30
                 ....*....|....*....|....*....|.
gi 484854295  54 DIVKVHSGPYKGKEGQVLEVIPKEYRITVEG 84
Cdd:COG0198    9 DTVIVIAGKDKGKRGKVLKVLPKKNRVIVEG 39
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 49-76 1.48e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 36.92  E-value: 1.48e-04
                           10        20
                   ....*....|....*....|....*...
gi 484854295    49 PISVKDIVKVHSGPYKGKEGQVLEVIPK 76
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVDGE 28
 
Name Accession Description Interval E-value
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 9-123 3.20e-37

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 123.00  E-value: 3.20e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295    9 SPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGCIeT 88
Cdd:pfam16906   1 SSSRRKQRKAHFNAPSHIRRKLMSAPLSKELREKYGVRSLPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGVT-R 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484854295   89 GEKEEETKNALIHPSSVTIVKFSMEDGREEKLEKR 123
Cdd:pfam16906  80 EKANGTTVPVPIHPSKVVITKLKLDKDRKKILERK 114
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 9-123 1.08e-21

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 83.36  E-value: 1.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295    9 SPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGcIET 88
Cdd:TIGR01080   1 SKQPRKQRKALFTAPLHERRKLMSAPLSKELREKYGKRALPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEG-VTK 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 484854295   89 GEKEEETKNALIHPSSVTIVKFSMEDGREEKLEKR 123
Cdd:TIGR01080  80 EKVDGTEVPVPLHPSNVMITKLHLDDEKRKKLLER 114
PTZ00194 PTZ00194
60S ribosomal protein L26; Provisional
 6-133 1.14e-21

60S ribosomal protein L26; Provisional


Pssm-ID: 185508  Cd Length: 143  Bit Score: 84.03  E-value: 1.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 484854295   6 KTKSPSRRKQRKSYFTATTKDRLKRMSSHLCEDLKSTYGFRAFPISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGc 85
Cdd:PTZ00194   3 SIVSSSRRKARKAHFTAPSHLRRKLMSAPLSKELRAKYNVRSMPVRKDDEVMVVRGHHKGREGKVTAVYRKKWVIHIEK- 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 484854295  86 IETGEKEEETKNALIHPSSVTIVKFSMEDGREEKLEkRKNAREETLRR 133
Cdd:PTZ00194  82 ITREKANGEPVQIGIHPSNVIITKLKLNKDRKAILE-RKARSTKSDKG 128
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 54-107 8.58e-10

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 51.36  E-value: 8.58e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 484854295  54 DIVKVHSGPYKGKEGQVLEVIPKEYRITVEGC----------IETGEKEEETKNALIHPSSVTI 107
Cdd:cd06089    2 DEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVnvvkkhvkpsQENPQGGIIEVEAPIHISNVML 65
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 52-83 4.17e-07

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 43.53  E-value: 4.17e-07
                          10        20        30
                  ....*....|....*....|....*....|..
gi 484854295   52 VKDIVKVHSGPYKGKEGQVLEVIPKEYRITVE 83
Cdd:pfam00467   1 KGDVVRVIAGPFKGKVGKVVEVDDKKNRVLVE 32
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 54-84 1.67e-06

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 43.51  E-value: 1.67e-06
                         10        20        30
                 ....*....|....*....|....*....|.
gi 484854295  54 DIVKVHSGPYKGKEGQVLEVIPKEYRITVEG 84
Cdd:COG0198    9 DTVIVIAGKDKGKRGKVLKVLPKKNRVIVEG 39
rplX PRK12281
50S ribosomal protein L24; Reviewed
 54-85 7.65e-06

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 41.18  E-value: 7.65e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 484854295  54 DIVKVHSGPYKGKEGQVLEVIPKEYRITVEGC 85
Cdd:PRK12281  11 DMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGV 42
KOW cd00380
KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known ...
 53-84 1.21e-04

KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The KOW motif contains an invariants glycine residue and comprises alternating blocks of hydrophilic and hydrophobic residues.


Pssm-ID: 240504  Cd Length: 49  Bit Score: 37.58  E-value: 1.21e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 484854295  53 KDIVKVHSGPYKGKEGQVLEVIPKEYRITVEG 84
Cdd:cd00380    1 GDVVRVLRGPYKGREGVVVDIDPRFGIVTVKG 32
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 49-76 1.48e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 36.92  E-value: 1.48e-04
                           10        20
                   ....*....|....*....|....*...
gi 484854295    49 PISVKDIVKVHSGPYKGKEGQVLEVIPK 76
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVDGE 28
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 50-85 1.49e-04

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 38.40  E-value: 1.49e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 484854295   50 ISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVEGC 85
Cdd:TIGR01079   3 IKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGV 38
KOW_NusG cd06091
NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; KOW_NusG motif ...
 50-83 9.22e-04

NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; KOW_NusG motif is one of the two domains of N-Utilization Substance G (NusG) a transcription elongation and Rho-termination factor in bacteria and archaea. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The eukaryotic ortholog of NusG is Spt5 with multiple KOW motifs at its C-terminus.


Pssm-ID: 240515 [Multi-domain]  Cd Length: 56  Bit Score: 35.13  E-value: 9.22e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 484854295  50 ISVKDIVKVHSGPYKGKEGQVLEVIPKEYRITVE 83
Cdd:cd06091    4 FEVGDTVRIISGPFAGFEGKVEEIDEEKGKVKVL 37
rpl24 CHL00141
ribosomal protein L24; Validated
 50-84 7.78e-03

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 33.46  E-value: 7.78e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 484854295  50 ISVK--DIVKVHSGPYKGKEGQVLEVIPKEYRITVEG 84
Cdd:CHL00141   7 MHVKigDTVKIISGSDKGKIGEVLKIIKKSNKVIVKG 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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