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Conserved domains on  [gi|2066012622|gb|KAG7721120|]
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hypothetical protein KL913_000856 [Ogataea haglerorum]

Protein Classification

glycerol-3-phosphate dehydrogenase family protein( domain architecture ID 11496765)

glycerol-3-phosphate dehydrogenase family protein is similar to human L-alpha-glycerol-3-phosphate dehydrogenase 1 (GPD1), which catalyzes the reversible biological conversion of dihydroxyacetone (DHAP) to glycerol-3-phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 29-376 0e+00

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


:

Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 617.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKELPQEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:TIGR03376   1 RVAVVGSGNWGTAIAKIVAENARALPELFEESVRMWVFEEEIEGRNLTEIINTTHENVKYLPGIKLPANLVAVPDLVEAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQKWSE 188
Cdd:TIGR03376  81 KGADILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDGVKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 189 TTVAYRIPEDFrgegkDVDQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIGLVE 268
Cdd:TIGR03376 161 TTVGYRDPADF-----DVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 269 MIKFAHMFFDDCQStTFTHESAGVADIITTCAGGRNVRVGRYMAEHKVSGFEAEKVLLNGQSCQGLHTTKEVYELLAAKN 348
Cdd:TIGR03376 236 MIKFARMFFPTGEV-TFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKN 314

                         330       340
                  ....*....|....*....|....*...
gi 2066012622 349 VIDEFPLFNATYQIIYEGLPMEKLPDLL 376
Cdd:TIGR03376 315 KDDEFPLFEAVYQILYEGLPPKKLPECL 342
 
Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 29-376 0e+00

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 617.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKELPQEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:TIGR03376   1 RVAVVGSGNWGTAIAKIVAENARALPELFEESVRMWVFEEEIEGRNLTEIINTTHENVKYLPGIKLPANLVAVPDLVEAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQKWSE 188
Cdd:TIGR03376  81 KGADILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDGVKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 189 TTVAYRIPEDFrgegkDVDQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIGLVE 268
Cdd:TIGR03376 161 TTVGYRDPADF-----DVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 269 MIKFAHMFFDDCQStTFTHESAGVADIITTCAGGRNVRVGRYMAEHKVSGFEAEKVLLNGQSCQGLHTTKEVYELLAAKN 348
Cdd:TIGR03376 236 MIKFARMFFPTGEV-TFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKN 314

                         330       340
                  ....*....|....*....|....*...
gi 2066012622 349 VIDEFPLFNATYQIIYEGLPMEKLPDLL 376
Cdd:TIGR03376 315 KDDEFPLFEAVYQILYEGLPPKKLPECL 342
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 27-380 1.61e-153

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 437.14  E-value: 1.61e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  27 PFRLTVVGSGNWGSTIAKVVAENAKELPqEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVD 106
Cdd:PTZ00345   11 PLKVSVIGSGNWGSAISKVVGENTQRNY-IFHNEVRMWVLEEIVEGEKLSDIINTKHENVKYLPGIKLPDNIVAVSDLKE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 107 ACSDADIIIFNIPHQFLPRILAQLK--GKVNPKARAISCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQ 184
Cdd:PTZ00345   90 AVEDADLLIFVIPHQFLESVLSQIKenNNLKKHARAISLTKGIIVENGKPVLCSDVIEEELGIPCCALSGANVANDVARE 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 185 KWSETTVAYripedfrgEGKDvDQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRI 264
Cdd:PTZ00345  170 EFSEATIGC--------EDKD-DALIWQRLFDRPYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRI 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 265 GLVEMIKFAHMFFDDCQSTTFtHESAGVADIITTCAGGRNVRVGRYMAEH--KVSGFEAEKVLLNGQSCQGLHTTKEVYE 342
Cdd:PTZ00345  241 GLEEMKLFGKIFFPNVMDETF-FESCGLADLITTCLGGRNVRCAAEFAKRngKKSWEEIEAELLNGQKLQGTVTLKEVYE 319

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2066012622 343 LLAAKNVIDEFPLFNATYQIIYEGLPMEKLPDLLEASE 380
Cdd:PTZ00345  320 VLESHDLKKEFPLFTVTYKIAFEGADPSSLIDVLSTNE 357
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 29-368 8.43e-84

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 258.04  E-value: 8.43e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWVFEEEVdgrklTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:COG0240     2 KIAVLGAGSWGTALAKVLARNGHE--------VTLWGRDPEV-----AEEINETRENPRYLPGVKLPENLRATSDLEEAL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvsKDGCKLLSNYITEELG--IYCGALSGANLAPEVARQKW 186
Cdd:COG0240    69 AGADLVLLAVPSQALREVLEQLAPLLPPGAPVVSATKGIE--PGTGLLMSEVIAEELPgaLRIAVLSGPSFAEEVARGLP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 187 SETTVAyripedfrgeGKDVDQ-NVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVM-Ri 264
Cdd:COG0240   147 TAVVVA----------SEDEEVaERLQELLSTPYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALItR- 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 265 GLVEMIKFAHMFfdDCQSTTFThESAGVADIITTCAG--GRNVRVGRYMAEhkvsGFEAEKVLLN-GQSCQGLHTTKEVY 341
Cdd:COG0240   216 GLAEMTRLGVAL--GARPETFM-GLAGLGDLVLTCTSdlSRNRRFGLALGK----GKSLEEALAEmGMVAEGVYTAKAVY 288

                         330       340
                  ....*....|....*....|....*..
gi 2066012622 342 ELLAAKNVidEFPLFNATYQIIYEGLP 368
Cdd:COG0240   289 ELAEKLGV--EMPITEAVYAVLYEGKS 313
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 31-193 4.26e-59

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 188.55  E-value: 4.26e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  31 TVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWVFEEEvdgrkLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDACSD 110
Cdd:pfam01210   3 AVLGAGSWGTALAKVLADNGHE--------VRLWGRDEE-----LIEEINTTHENVRYLPGIKLPENLKATTDLAEALKG 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 111 ADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvsKDGCKLLSNYITEELGIY--CGALSGANLAPEVARQKWSE 188
Cdd:pfam01210  70 ADIIVIVVPSQALREVLKQLKGLLKPDAILVSLSKGIE--PGTLKLLSEVIEEELGIQppIAVLSGPSHAEEVAQGLPTA 147


                  ....*
gi 2066012622 189 TTVAY 193
Cdd:pfam01210 148 TVIAS 152
 
Name Accession Description Interval E-value
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 29-376 0e+00

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 617.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKELPQEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:TIGR03376   1 RVAVVGSGNWGTAIAKIVAENARALPELFEESVRMWVFEEEIEGRNLTEIINTTHENVKYLPGIKLPANLVAVPDLVEAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQKWSE 188
Cdd:TIGR03376  81 KGADILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDGVKLLSDIIEEELGIPCGVLSGANLANEVAKEKFSE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 189 TTVAYRIPEDFrgegkDVDQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIGLVE 268
Cdd:TIGR03376 161 TTVGYRDPADF-----DVDARVLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 269 MIKFAHMFFDDCQStTFTHESAGVADIITTCAGGRNVRVGRYMAEHKVSGFEAEKVLLNGQSCQGLHTTKEVYELLAAKN 348
Cdd:TIGR03376 236 MIKFARMFFPTGEV-TFTFESCGVADLITTCLGGRNFKVGRAFAKTGKSLEELEKELLNGQSLQGVATAKEVHELLKNKN 314

                         330       340
                  ....*....|....*....|....*...
gi 2066012622 349 VIDEFPLFNATYQIIYEGLPMEKLPDLL 376
Cdd:TIGR03376 315 KDDEFPLFEAVYQILYEGLPPKKLPECL 342
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 27-380 1.61e-153

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 437.14  E-value: 1.61e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  27 PFRLTVVGSGNWGSTIAKVVAENAKELPqEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVD 106
Cdd:PTZ00345   11 PLKVSVIGSGNWGSAISKVVGENTQRNY-IFHNEVRMWVLEEIVEGEKLSDIINTKHENVKYLPGIKLPDNIVAVSDLKE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 107 ACSDADIIIFNIPHQFLPRILAQLK--GKVNPKARAISCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQ 184
Cdd:PTZ00345   90 AVEDADLLIFVIPHQFLESVLSQIKenNNLKKHARAISLTKGIIVENGKPVLCSDVIEEELGIPCCALSGANVANDVARE 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 185 KWSETTVAYripedfrgEGKDvDQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRI 264
Cdd:PTZ00345  170 EFSEATIGC--------EDKD-DALIWQRLFDRPYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRI 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 265 GLVEMIKFAHMFFDDCQSTTFtHESAGVADIITTCAGGRNVRVGRYMAEH--KVSGFEAEKVLLNGQSCQGLHTTKEVYE 342
Cdd:PTZ00345  241 GLEEMKLFGKIFFPNVMDETF-FESCGLADLITTCLGGRNVRCAAEFAKRngKKSWEEIEAELLNGQKLQGTVTLKEVYE 319

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2066012622 343 LLAAKNVIDEFPLFNATYQIIYEGLPMEKLPDLLEASE 380
Cdd:PTZ00345  320 VLESHDLKKEFPLFTVTYKIAFEGADPSSLIDVLSTNE 357
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 29-368 8.43e-84

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 258.04  E-value: 8.43e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWVFEEEVdgrklTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:COG0240     2 KIAVLGAGSWGTALAKVLARNGHE--------VTLWGRDPEV-----AEEINETRENPRYLPGVKLPENLRATSDLEEAL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvsKDGCKLLSNYITEELG--IYCGALSGANLAPEVARQKW 186
Cdd:COG0240    69 AGADLVLLAVPSQALREVLEQLAPLLPPGAPVVSATKGIE--PGTGLLMSEVIAEELPgaLRIAVLSGPSFAEEVARGLP 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 187 SETTVAyripedfrgeGKDVDQ-NVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVM-Ri 264
Cdd:COG0240   147 TAVVVA----------SEDEEVaERLQELLSTPYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALItR- 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 265 GLVEMIKFAHMFfdDCQSTTFThESAGVADIITTCAG--GRNVRVGRYMAEhkvsGFEAEKVLLN-GQSCQGLHTTKEVY 341
Cdd:COG0240   216 GLAEMTRLGVAL--GARPETFM-GLAGLGDLVLTCTSdlSRNRRFGLALGK----GKSLEEALAEmGMVAEGVYTAKAVY 288

                         330       340
                  ....*....|....*....|....*..
gi 2066012622 342 ELLAAKNVidEFPLFNATYQIIYEGLP 368
Cdd:COG0240   289 ELAEKLGV--EMPITEAVYAVLYEGKS 313
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
29-368 4.48e-73

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 230.34  E-value: 4.48e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWVFEEEVdgrklTEIINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:PRK00094    3 KIAVLGAGSWGTALAIVLARNGHD--------VTLWARDPEQ-----AAEINADRENPRYLPGIKLPDNLRATTDLAEAL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvsKDGCKLLSNYITEELG--IYCGALSGANLAPEVARQKW 186
Cdd:PRK00094   70 ADADLILVAVPSQALREVLKQLKPLLPPDAPIVWATKGIE--PGTGKLLSEVLEEELPdlAPIAVLSGPSFAKEVARGLP 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 187 SETTVAyripedfrgeGKDVDQ-NVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIG 265
Cdd:PRK00094  148 TAVVIA----------STDEELaERVQELFHSPYFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRG 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 266 LVEMIKFA-HMffdDCQSTTFThESAGVADIITTCAG--GRNVRVGRYMAEhkvsGFEAEKVLLN-GQSCQGLHTTKEVY 341
Cdd:PRK00094  218 LAEITRLGvAL---GANPETFL-GLAGLGDLVLTCTSplSRNRRFGLALGQ----GKSLEEALAEiGMVAEGVRTAKAVY 289

                         330       340
                  ....*....|....*....|....*..
gi 2066012622 342 ELLAAKNVidEFPLFNATYQIIYEGLP 368
Cdd:PRK00094  290 ELAKKLGV--EMPITEAVYAVLYEGKD 314
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 31-193 4.26e-59

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 188.55  E-value: 4.26e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  31 TVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWVFEEEvdgrkLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDACSD 110
Cdd:pfam01210   3 AVLGAGSWGTALAKVLADNGHE--------VRLWGRDEE-----LIEEINTTHENVRYLPGIKLPENLKATTDLAEALKG 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 111 ADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvsKDGCKLLSNYITEELGIY--CGALSGANLAPEVARQKWSE 188
Cdd:pfam01210  70 ADIIVIVVPSQALREVLKQLKGLLKPDAILVSLSKGIE--PGTLKLLSEVIEEELGIQppIAVLSGPSHAEEVAQGLPTA 147


                  ....*
gi 2066012622 189 TTVAY 193
Cdd:pfam01210 148 TVIAS 152
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 227-374 3.66e-55

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 177.97  E-value: 3.66e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 227 DVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIGLVEMIKFAHMFFddCQSTTFThESAGVADIITTCAGG--RN 304
Cdd:pfam07479   1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALG--AKPETFF-GLAGLGDLIVTCTSGlsRN 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2066012622 305 VRVGRYMAEhkvsGFEAEKVLLN-GQSCQGLHTTKEVYELLAAKNVidEFPLFNATYQIIYEGLPMEKLPD 374
Cdd:pfam07479  78 RRFGEALGK----GKSLEEAEKElGQVAEGVYTAKAVYELAKKLGV--EMPIFEAVYRILYEGKSPEEALE 142
PRK12439 PRK12439
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 23-315 2.56e-44

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 171500 [Multi-domain]  Cd Length: 341  Bit Score: 156.10  E-value: 2.56e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  23 PESKPFRLTVVGSGNWGSTIAKVVAENAKELpqefhqivkMWVFEEEVdgrklTEIINTDHENVKYLP-DVKLPDNIVAI 101
Cdd:PRK12439    3 AAKREPKVVVLGGGSWGTTVASICARRGPTL---------QWVRSAET-----ADDINDNHRNSRYLGnDVVLSDTLRAT 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 102 PDIVDACSDADIIIFNIPHQFLPRILAQLKGKVNPKARAISCLKGLEvskDGCKLLSNYITEEL--GIYCGALSGANLAP 179
Cdd:PRK12439   69 TDFAEAANCADVVVMGVPSHGFRGVLTELAKELRPWVPVVSLVKGLE---QGTNMRMSQIIEEVlpGHPAGILAGPNIAR 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 180 EVARQKWSETTVAyrIPedfrgegkdvDQNV---LRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDN 256
Cdd:PRK12439  146 EVAEGYAAAAVLA--MP----------DQHLatrLSPLFRTRRFRVYTTDDVVGVEMAGALKNVFAIAVGMGYSLGIGEN 213

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2066012622 257 AKAAVMRIGLVEMIKFAHMFfdDCQSTTFTHeSAGVADIITTCAG--GRNVRVGRYMAEHK 315
Cdd:PRK12439  214 TRAMVIARALREMTKLGVAM--GGNPETFAG-LAGMGDLIVTCTSqrSRNRHVGEQLGAGK 271
PRK14618 PRK14618
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 29-377 7.12e-41

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237770 [Multi-domain]  Cd Length: 328  Bit Score: 146.94  E-value: 7.12e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAkelpqefhQIVKMWVFEEEVDGRklteiINTDHENVKYLPDVKLPDNIVAIPDIVDAC 108
Cdd:PRK14618    6 RVAVLGAGAWGTALAVLAASKG--------VPVRLWARRPEFAAA-----LAAERENREYLPGVALPAELYPTADPEEAL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 109 SDADIIIFNIPHQFLPRILAQLkgkvnPKARAI-SCLKGLEVSKDGCKLLSNYITEELGIYCGALSGANLAPEVARQKWS 187
Cdd:PRK14618   73 AGADFAVVAVPSKALRETLAGL-----PRALGYvSCAKGLAPDGGRLSELARVLEFLTQARVAVLSGPNHAEEIARFLPA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 188 ETTVAYRIPedfrgegkDVDQNVlRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAVMRIGLV 267
Cdd:PRK14618  148 ATVVASPEP--------GLARRV-QAAFSGPSFRVYTSRDRVGVELGGALKNVIALAAGMVDGLKLGDNAKAALITRGLR 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 268 EMIKFAHMFfdDCQSTTFtHESAGVADIITTcAGGRNVRvGRYMAEHKVSGFEAEKVLLNGQSCQGLHTTKEVYELLAAK 347
Cdd:PRK14618  219 EMVRFGVAL--GAEEATF-YGLSGLGDLIAT-ATSPHSR-NRAAGEAIVRGVDREHLEAGGKVVEGLYTVKALDAWAKAH 293

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2066012622 348 NVidEFPLFNATYQIIYEGL-PMEKLPDLLE 377
Cdd:PRK14618  294 GH--DLPIVEAVARVARGGWdPLAGLRSLMG 322
PRK14620 PRK14620
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 29-371 2.39e-27

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 173083 [Multi-domain]  Cd Length: 326  Bit Score: 110.31  E-value: 2.39e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  29 RLTVVGSGNWGSTIAKVVAENAKElpqefhqiVKMWvfeeevdGRKLT--EIINTDHENVKYLPDVKLPDNIVAIPDIVD 106
Cdd:PRK14620    2 KISILGAGSFGTAIAIALSSKKIS--------VNLW-------GRNHTtfESINTKRKNLKYLPTCHLPDNISVKSAIDE 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 107 ACSD-ADIIIFNIPHQFLPRILAQLKGKVNPKARAI-SCLKGLEVSKdgCKLLSNYITEELG---IYcgALSGANLAPEV 181
Cdd:PRK14620   67 VLSDnATCIILAVPTQQLRTICQQLQDCHLKKNTPIlICSKGIEKSS--LKFPSEIVNEILPnnpIA--ILSGPSFAKEI 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 182 ARQKWSETTVAyripedfrGEGKDVDQNVLRNLfHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGWGDNAKAAV 261
Cdd:PRK14620  143 AEKLPCSIVLA--------GQNETLGSSLISKL-SNENLKIIYSQDIIGVQIGAALKNIIAIACGIVLGKNLGNNAHAAV 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 262 MRIGLVEmIKFAHMFFDDCQSTTFTHESAGVADIITTC--AGGRNVRVGRYMAEhkvsGFEAEKVLLNGQSC-QGLHTTK 338
Cdd:PRK14620  214 ITKGMNE-IKTLYSAKNGSIDLNTLIGPSCLGDLILTCttLHSRNMSFGFKIGN----GFNINQILSEGKSViEGFSTVK 288

                         330       340       350
                  ....*....|....*....|....*....|...
gi 2066012622 339 EVYELlaAKNVIDEFPLFNATYQIIYEGLPMEK 371
Cdd:PRK14620  289 PLISL--AKKLNIELPICESIYNLLYENISLEK 319
PRK14619 PRK14619
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 25-349 1.81e-21

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237771 [Multi-domain]  Cd Length: 308  Bit Score: 93.51  E-value: 1.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622  25 SKPFRLTVVGSGNWGSTIAKVVAENakelpqefHQIVKMWVFEEEVDgrkLTEIIntdhenvkylpdvklpdnivaipdi 104
Cdd:PRK14619    2 TQPKTIAILGAGAWGSTLAGLASAN--------GHRVRVWSRRSGLS---LAAVL------------------------- 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 105 vdacSDADIIIFNIPHQFLPRILAQLKGkVNPKARAI--SCLKGLE---------VSKDGCKLLSNYIteelgiycgaLS 173
Cdd:PRK14619   46 ----ADADVIVSAVSMKGVRPVAEQVQA-LNLPPETIivTATKGLDpettrtpsqIWQAAFPNHPVVV----------LS 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 174 GANLAPEVARQKWSETTVAYRIPEDfrgegkdvdQNVLRNLFHRPYFHVRVVDDVAGVSLSGALKNVVAMAAGFVEGLGW 253
Cdd:PRK14619  111 GPNLSKEIQQGLPAATVVASRDLAA---------AETVQQIFSSERFRVYTNSDPLGTELGGTLKNVIAIAAGVCDGLQL 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2066012622 254 GDNAKAAVMRIGLVEMIKFAHMFfdDCQSTTFTHESaGVADIITTCAG--GRNVRVGRYMAEhkvsGFEAEKVLLN-GQS 330
Cdd:PRK14619  182 GTNAKAALVTRALPEMIRVGTHL--GAQTETFYGLS-GLGDLLATCTSplSRNYQVGYGLAQ----GKSLEQILAElEGT 254

                         330
                  ....*....|....*....
gi 2066012622 331 CQGLHTTKEVYELLAAKNV 349
Cdd:PRK14619  255 AEGVNTANVLVQLAQQQNI 273
GPD_NAD_C_bact pfam20618
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent ...
 290-358 4.70e-04

Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent glycerol-3-phosphate dehydrogenase (GPD) from bacteria and archaea. GPD catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate.


Pssm-ID: 466767 [Multi-domain]  Cd Length: 66  Bit Score: 38.25  E-value: 4.70e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2066012622 290 AGVADIITTCAGG--RNVRVGRYMAehkvSGF-EAEKVllNGQSCQGLHTTKEVYELLAAKNVIdEFPLFNA 358
Cdd:pfam20618   1 AGLGDLVLTCTSDlsRNRTFGLLLG----KGMtLAEAG--NGQVAEGVRTAKAVAAILARAHNV-EMPILEA 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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