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Conserved domains on  [gi|62912468|ref|NP_001017367|]
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C4b-binding protein beta chain isoform 1 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 47-208 9.34e-17

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.39  E-value: 9.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 126
Cdd:PHA02927  52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468  127 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 200
Cdd:PHA02927 132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                 ....*...
gi 62912468  201 ECEKALLA 208
Cdd:PHA02927 210 TISNGYLS 217
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 47-208 9.34e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.39  E-value: 9.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 126
Cdd:PHA02927  52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468  127 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 200
Cdd:PHA02927 132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                 ....*...
gi 62912468  201 ECEKALLA 208
Cdd:PHA02927 210 TISNGYLS 217
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 81-135 2.62e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 2.62e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 62912468  81 CPDP-VLVNGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 135
Cdd:cd00033   1 CPPPpVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
139-191 7.85e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 7.85e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468   139 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
Cdd:pfam00084   1 CPPPPDIPNGKVSAtkNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 81-134 1.99e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 1.99e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468     81 CPDP-VLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
Cdd:smart00032   1 CPPPpDIENGTVtSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 47-208 9.34e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.39  E-value: 9.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 126
Cdd:PHA02927  52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468  127 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 200
Cdd:PHA02927 132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                 ....*...
gi 62912468  201 ECEKALLA 208
Cdd:PHA02927 210 TISNGYLS 217
PHA02639 PHA02639
EEV host range protein; Provisional
 47-191 6.81e-15

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.39  E-value: 6.81e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   47 YVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCPDP-VLVNGE-FSSSGPVNVSDKITFMCNDH----YILKGSN 117
Cdd:PHA02639  48 YTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCMLKECNDPpSIINGKiYNKREMYKVGDEIYYVCNEHkgvqYSLVGNE 127

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62912468  118 RSQCLEDHTWAPPFPICKSRDCDPPGNPvHGYFEG----NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Cdd:PHA02639 128 KITCIQDKSWKPDPPICKMINCRFPALQ-NGYINGipsnKKFYYKTRVGFSCKSGFDLVGEKYSTCnINATWFPSIPTC 205
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 23-134 1.17e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 68.53  E-value: 1.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   23 CPELPPVDNSIFVAKE---VEGQILgTYVCIKGYHLVGKKTLFCNASkEWDNTTTeCRLGHCPDPVLVNGEFSSSGPVNV 99
Cdd:PHA02927 148 CQSPPSISNGRHNGYEdfyTDGSVV-TYSCNSGYSLIGNSGVLCSGG-EWSDPPT-CQIVKCPHPTISNGYLSSGFKRSY 224

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 62912468  100 S--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
Cdd:PHA02927 225 SynDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 81-135 2.62e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 2.62e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 62912468  81 CPDP-VLVNGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 135
Cdd:cd00033   1 CPPPpVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 139-192 2.99e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 2.99e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 62912468 139 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCK 192
Cdd:cd00033   1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
139-191 7.85e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 7.85e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468   139 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
Cdd:pfam00084   1 CPPPPDIPNGKVSAtkNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 81-134 1.99e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 1.99e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468     81 CPDP-VLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
Cdd:smart00032   1 CPPPpDIENGTVtSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 139-191 2.08e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 2.08e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468    139 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 23-191 2.68e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 56.20  E-value: 2.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC----NASKEWDNTTTECRLGHCPD-PVLVNG------EF 91
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCelgsTGSMVWNPEAPICESVKCQSpPSISNGrhngyeDF 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   92 SSSGPVnvsdkITFMCNDHYILKGSNRSQClEDHTWAPPfPICKSRDCDPPgNPVHGYFEGN---NFTLGSTISYYCEDR 168
Cdd:PHA02927 166 YTDGSV-----VTYSCNSGYSLIGNSGVLC-SGGEWSDP-PTCQIVKCPHP-TISNGYLSSGfkrSYSYNDNVDFKCKYG 237

                        170       180
                 ....*....|....*....|....
gi 62912468  169 YYLVGVQEQQCVDGE-WSSALPVC 191
Cdd:PHA02927 238 YKLSGSSSSTCSPGNtWQPELPKC 261
PHA02817 PHA02817
EEV Host range protein; Provisional
 81-191 1.96e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 53.41  E-value: 1.96e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   81 CPDPVLVNGEFSSSGPV-NVSDKITFMCNDH-----YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG---NPVHGYFE 151
Cdd:PHA02817  25 CYPPSIKNGYIYNKKTEyNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPAlqnGFVNGIPD 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 62912468  152 GNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Cdd:PHA02817 105 SKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
 16-138 1.98e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 53.41  E-value: 1.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   16 SASDAEHCPELPPVDNSIFVAKEVEGQILG--TYVCIKG-----YHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVN 88
Cdd:PHA02817  17 SLCDLNKCCYPPSIKNGYIYNKKTEYNIGSnvTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQN 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 62912468   89 GEFS---SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD 138
Cdd:PHA02817  97 GFVNgipDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDN 149
Sushi pfam00084
Sushi repeat (SCR repeat);
81-134 1.81e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 1.81e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 62912468    81 CPDP-VLVNGEFSSS-GPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
Cdd:pfam00084   1 CPPPpDIPNGKVSATkNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 103-194 3.66e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 3.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468  103 ITFMCNDHYILKGSNRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHG--YFEGNNFTLGSTISYYCED----RYYLVG 173
Cdd:PHA02639  46 IEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCMLKECNDPPSIINGkiYNKREMYKVGDEIYYVCNEhkgvQYSLVG 125

                         90       100
                 ....*....|....*....|..
gi 62912468  174 VQEQQCV-DGEWSSALPVCKLI 194
Cdd:PHA02639 126 NEKITCIqDKSWKPDPPICKMI 147
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 64-200 8.30e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 48.93  E-value: 8.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   64 NASKEWDNTTTeCRLGHCPDPVLVNGefsSSGPV----NVSDKITFMCNDHYILKGSNRSQCLEDhTWAPpFPICKSRdC 139
Cdd:PHA02954 114 NGNTSWNDTVT-CPNAECQPLQLEHG---SCQPVkekySFGEHITINCDVGYEVIGASYISCTAN-SWNV-IPSCQQK-C 186

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62912468  140 DPPgNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPKP 200
Cdd:PHA02954 187 DIP-SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVLPICVRSNEEFDP 246
PHA02831 PHA02831
EEV host range protein; Provisional
 137-195 2.53e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 2.53e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 62912468  137 RDCDPPGNPVHGYFEG--NNFTLGSTISYYCE----DRYYLVGVQEQQCVDGEWSSALPVCKLIQ 195
Cdd:PHA02831  76 RNCKDPVTILNGYIKNkkDQYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIR 140
PHA02831 PHA02831
EEV host range protein; Provisional
 46-134 3.84e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.91  E-value: 3.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   46 TYVC----IKGYHLVGKKTLFCnASKEWDNTTTECRLGHCPDPVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQ 120
Cdd:PHA02831 103 TYACkvnkLEKYSIVGNETVKC-INKQWVPKYPVCKLIRCKYPALQNGFLNVfEKKFYYGDIVNFKCKKGFILLGSSVST 181

                         90
                 ....*....|....
gi 62912468  121 CLEDHTWAPPFPIC 134
Cdd:PHA02831 182 CDINSIWYPGIPKC 195
PHA02831 PHA02831
EEV host range protein; Provisional
 80-191 4.37e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 4.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   80 HCPDPVLV-NGEFSS-SGPVNVSDKITFMCN----DHYILKGSNRSQCLeDHTWAPPFPICKSRDCDPPG--NPVHGYFE 151
Cdd:PHA02831  77 NCKDPVTIlNGYIKNkKDQYSFGDSVTYACKvnklEKYSIVGNETVKCI-NKQWVPKYPVCKLIRCKYPAlqNGFLNVFE 155

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 62912468  152 gNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Cdd:PHA02831 156 -KKFYYGDIVNFKCKKGFILLGSSVSTCdINSIWYPGIPKC 195
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 23-77 4.70e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 42.84  E-value: 4.70e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 62912468  23 CPELPPVDNSIFV---AKEVEGQILgTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR 77
Cdd:cd00033   1 CPPPPVPENGTVTgskGSYSYGSTV-TYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 23-76 1.52e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.36  E-value: 1.52e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 62912468     23 CPELPPVDNSIFVAKE---VEGQILgTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 76
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtySYGDTV-TYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-200 3.98e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.79  E-value: 3.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62912468   98 NVSDKITFMCNDHYILK--GSNRSQClEDHTWAPpFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQ 175
Cdd:PHA02927  45 NIGDTIEYLCLPGYRKQkmGPIYAKC-TGTGWTL-FNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGES 122

                         90       100       110
                 ....*....|....*....|....*....|
gi 62912468  176 EQQCVDGE-----WSSALPVCKLIQEAPKP 200
Cdd:PHA02927 123 KSYCELGStgsmvWNPEAPICESVKCQSPP 152
PHA02817 PHA02817
EEV Host range protein; Provisional
 134-194 2.51e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 38.00  E-value: 2.51e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62912468  134 CKSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCED-----RYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNntrgvRYTLVGEKNIICeKDGKWNKEFPVCKII 87
Sushi pfam00084
Sushi repeat (SCR repeat);
23-76 9.81e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 33.63  E-value: 9.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 62912468    23 CPELPPVDNSIFVAKEVE---GQILgTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 76
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEynyGASV-SYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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