|
Name |
Accession |
Description |
Interval |
E-value |
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2698-2792 |
1.29e-28 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 111.54 E-value: 1.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2698 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2777
Cdd:smart00557 1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 2778 EHVPGSPFLVMIVDT 2792
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2604-2695 |
9.92e-22 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.90 E-value: 9.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2604 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2682
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 2683 VKGSPFVVHVSLP 2695
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
15-107 |
1.90e-21 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.13 E-value: 1.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 95 VPDAPFACNVGAP 107
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2509-2598 |
1.65e-20 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 88.43 E-value: 1.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2509 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2587
Cdd:smart00557 2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|.
gi 922581632 2588 VKGSPFAVSAD 2598
Cdd:smart00557 81 IPGSPFTVKVG 91
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1420-1503 |
7.54e-19 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.42 E-value: 7.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1420 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVC---EGRVPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1494
Cdd:smart00557 1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTgpsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
....*....
gi 922581632 1495 VPGSPFLCQ 1503
Cdd:smart00557 81 IPGSPFTVK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2100-2189 |
1.17e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.04 E-value: 1.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2100 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2179
Cdd:smart00557 4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
|
90
....*....|
gi 922581632 2180 SPFKTEVIDP 2189
Cdd:smart00557 84 SPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1174-1267 |
1.78e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 82.65 E-value: 1.78e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1174 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1252
Cdd:smart00557 1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 1253 EVLKNSPFEVNIVDA 1267
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
304-388 |
1.06e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 80.34 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557 5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*...
gi 922581632 381 PIKVEILP 388
Cdd:smart00557 85 PFTVKVGP 92
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1331-1420 |
6.26e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 78.03 E-value: 6.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1331 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1406
Cdd:smart00557 1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
|
90
....*....|....
gi 922581632 1407 PVTGSPFTCRAYDP 1420
Cdd:smart00557 80 HIPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1610-1689 |
1.95e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1610 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1688
Cdd:smart00557 13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
.
gi 922581632 1689 A 1689
Cdd:smart00557 93 A 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
212-297 |
1.99e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557 3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82
|
....*.
gi 922581632 292 GSPLSV 297
Cdd:smart00557 83 GSPFTV 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1927-2008 |
9.19e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.95 E-value: 9.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1927 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 2006
Cdd:smart00557 12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
|
..
gi 922581632 2007 DP 2008
Cdd:smart00557 92 PA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2285-2372 |
1.47e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.18 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2285 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2363
Cdd:smart00557 6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*....
gi 922581632 2364 PFTVNVVDP 2372
Cdd:smart00557 85 PFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2008-2096 |
3.07e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 73.41 E-value: 3.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2008 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 2084
Cdd:smart00557 1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|..
gi 922581632 2085 LSDGPYEVFISH 2096
Cdd:smart00557 81 IPGSPFTVKVGP 92
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1517-1600 |
1.39e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 71.48 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1517 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1595
Cdd:smart00557 11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88
|
....*
gi 922581632 1596 KAYDA 1600
Cdd:smart00557 89 KVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
119-197 |
2.64e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 70.71 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557 11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90
|
..
gi 922581632 196 ED 197
Cdd:smart00557 91 GP 92
|
|
| IG_FLMN super family |
cl42963 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2206-2279 |
3.78e-10 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
The actual alignment was detected with superfamily member smart00557:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 58.77 E-value: 3.78e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581632 2206 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2279
Cdd:smart00557 19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
|
| IG_FLMN super family |
cl42963 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2391-2467 |
3.60e-09 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
The actual alignment was detected with superfamily member smart00557:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 56.07 E-value: 3.60e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581632 2391 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2467
Cdd:smart00557 15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
|
|
| IG_FLMN super family |
cl42963 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1842-1905 |
5.01e-07 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
The actual alignment was detected with superfamily member smart00557:
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 49.91 E-value: 5.01e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1842 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1905
Cdd:smart00557 16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
759-1181 |
1.86e-05 |
|
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 759 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 838
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 839 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 915
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 916 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 986
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 987 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1055
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1056 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1135
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 922581632 1136 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1181
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
|
|
| Filamin super family |
cl44411 |
Filamin/ABP280 repeat; |
1754-1818 |
8.25e-04 |
|
Filamin/ABP280 repeat;
The actual alignment was detected with superfamily member pfam00630:
Pssm-ID: 395505 Cd Length: 89 Bit Score: 40.74 E-value: 8.25e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1754 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1818
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2698-2792 |
1.29e-28 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 111.54 E-value: 1.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2698 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2777
Cdd:smart00557 1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 2778 EHVPGSPFLVMIVDT 2792
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2695-2785 |
1.50e-22 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 93.89 E-value: 1.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2695 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2774
Cdd:pfam00630 1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
|
90
....*....|.
gi 922581632 2775 WHGEHVPGSPF 2785
Cdd:pfam00630 78 FNGQHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2604-2695 |
9.92e-22 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.90 E-value: 9.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2604 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2682
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 2683 VKGSPFVVHVSLP 2695
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
15-107 |
1.90e-21 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.13 E-value: 1.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 95 VPDAPFACNVGAP 107
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2509-2598 |
1.65e-20 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 88.43 E-value: 1.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2509 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2587
Cdd:smart00557 2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|.
gi 922581632 2588 VKGSPFAVSAD 2598
Cdd:smart00557 81 IPGSPFTVKVG 91
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1420-1503 |
7.54e-19 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.42 E-value: 7.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1420 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVC---EGRVPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1494
Cdd:smart00557 1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTgpsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
....*....
gi 922581632 1495 VPGSPFLCQ 1503
Cdd:smart00557 81 IPGSPFTVK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2100-2189 |
1.17e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.04 E-value: 1.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2100 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2179
Cdd:smart00557 4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
|
90
....*....|
gi 922581632 2180 SPFKTEVIDP 2189
Cdd:smart00557 84 SPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1174-1267 |
1.78e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 82.65 E-value: 1.78e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1174 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1252
Cdd:smart00557 1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 1253 EVLKNSPFEVNIVDA 1267
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2100-2183 |
2.11e-18 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 82.34 E-value: 2.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2100 VRASGDALRKAQRARTARFEVINVEQNrGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2179
Cdd:pfam00630 7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85
|
....
gi 922581632 2180 SPFK 2183
Cdd:pfam00630 86 SPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
304-388 |
1.06e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 80.34 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557 5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*...
gi 922581632 381 PIKVEILP 388
Cdd:smart00557 85 PFTVKVGP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
13-100 |
5.31e-17 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 78.10 E-value: 5.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 13 ADASSVSVYGENLRSASVGKTASFMVHAIGAEAkDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLAD 92
Cdd:pfam00630 2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80
|
....*...
gi 922581632 93 QRVPDAPF 100
Cdd:pfam00630 81 QHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1331-1420 |
6.26e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 78.03 E-value: 6.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1331 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1406
Cdd:smart00557 1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
|
90
....*....|....
gi 922581632 1407 PVTGSPFTCRAYDP 1420
Cdd:smart00557 80 HIPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1610-1689 |
1.95e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1610 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1688
Cdd:smart00557 13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
.
gi 922581632 1689 A 1689
Cdd:smart00557 93 A 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
212-297 |
1.99e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557 3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82
|
....*.
gi 922581632 292 GSPLSV 297
Cdd:smart00557 83 GSPFTV 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1927-2008 |
9.19e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.95 E-value: 9.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1927 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 2006
Cdd:smart00557 12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
|
..
gi 922581632 2007 DP 2008
Cdd:smart00557 92 PA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2285-2372 |
1.47e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.18 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2285 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2363
Cdd:smart00557 6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*....
gi 922581632 2364 PFTVNVVDP 2372
Cdd:smart00557 85 PFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2008-2096 |
3.07e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 73.41 E-value: 3.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2008 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 2084
Cdd:smart00557 1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|..
gi 922581632 2085 LSDGPYEVFISH 2096
Cdd:smart00557 81 IPGSPFTVKVGP 92
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1517-1600 |
1.39e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 71.48 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1517 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1595
Cdd:smart00557 11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88
|
....*
gi 922581632 1596 KAYDA 1600
Cdd:smart00557 89 KVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
119-197 |
2.64e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 70.71 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557 11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90
|
..
gi 922581632 196 ED 197
Cdd:smart00557 91 GP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2285-2366 |
5.72e-14 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 69.63 E-value: 5.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2285 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 2364
Cdd:pfam00630 9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
|
..
gi 922581632 2365 FT 2366
Cdd:pfam00630 88 FK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1597-1681 |
1.20e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 68.47 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1597 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1674
Cdd:pfam00630 1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80
|
....*..
gi 922581632 1675 ISVPGSP 1681
Cdd:pfam00630 81 QHIPGSP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2509-2593 |
1.62e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 68.08 E-value: 1.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2509 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2587
Cdd:pfam00630 5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82
|
....*.
gi 922581632 2588 VKGSPF 2593
Cdd:pfam00630 83 IPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1417-1500 |
2.97e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 67.70 E-value: 2.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1417 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1491
Cdd:pfam00630 1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
....*....
gi 922581632 1492 NEPVPGSPF 1500
Cdd:pfam00630 80 GQHIPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
304-383 |
3.02e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 64.62 E-value: 3.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 304 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 381
Cdd:pfam00630 8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
|
..
gi 922581632 382 IK 383
Cdd:pfam00630 88 FK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2005-2091 |
4.92e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 64.23 E-value: 4.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2005 VLDPSAVRV--IGLKNAPVGVEQQFSVDYTNSGASiASVEVRHGD-QTIPITVKKMKPGQLLCTFTPFVDGPHQVEVIID 2081
Cdd:pfam00630 1 AADASKVKAsgPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
90
....*....|
gi 922581632 2082 GVPLSDGPYE 2091
Cdd:pfam00630 80 GQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
213-294 |
9.36e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 63.08 E-value: 9.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 213 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 292
Cdd:pfam00630 7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85
|
..
gi 922581632 293 SP 294
Cdd:pfam00630 86 SP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1171-1261 |
1.89e-11 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 62.31 E-value: 1.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1171 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1249
Cdd:pfam00630 1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
|
90
....*....|..
gi 922581632 1250 FNKEVLKNSPFE 1261
Cdd:pfam00630 78 FNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1344-1414 |
1.18e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 60.00 E-value: 1.18e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1344 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1414
Cdd:pfam00630 18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1517-1594 |
2.68e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 59.22 E-value: 2.68e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581632 1517 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1594
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2206-2279 |
3.78e-10 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 58.77 E-value: 3.78e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581632 2206 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2279
Cdd:smart00557 19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2614-2689 |
4.91e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 58.45 E-value: 4.91e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581632 2614 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2689
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2186-2272 |
1.01e-09 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 57.30 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2186 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 2264
Cdd:pfam00630 1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
....*...
gi 922581632 2265 GFQIPGYP 2272
Cdd:pfam00630 80 GQHIPGSP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
119-192 |
2.41e-09 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 56.53 E-value: 2.41e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 119 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 192
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2391-2467 |
3.60e-09 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 56.07 E-value: 3.60e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581632 2391 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2467
Cdd:smart00557 15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2369-2459 |
2.53e-08 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 53.45 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2369 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2448
Cdd:pfam00630 1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
|
90
....*....|.
gi 922581632 2449 SIYLYWNELPV 2459
Cdd:pfam00630 73 TVSVKFNGQHI 83
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1930-2001 |
1.32e-07 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 51.52 E-value: 1.32e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1930 IVGEQTELKILIdSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPF 2001
Cdd:pfam00630 18 VVGKPAEFTVDT-RDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1842-1905 |
5.01e-07 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 49.91 E-value: 5.01e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1842 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1905
Cdd:smart00557 16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1842-1906 |
1.87e-06 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 48.05 E-value: 1.87e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1842 AGQKYSFDVNSDD-KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPIG 1906
Cdd:pfam00630 19 VGKPAEFTVDTRDaGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIP 84
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
759-1181 |
1.86e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 759 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 838
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 839 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 915
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 916 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 986
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 987 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1055
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1056 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1135
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 922581632 1136 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1181
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1087-1174 |
5.52e-05 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 44.13 E-value: 5.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1087 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1165
Cdd:smart00557 17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*....
gi 922581632 1166 PFAVRVYDA 1174
Cdd:smart00557 85 PFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1117-1167 |
6.46e-04 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 41.12 E-value: 6.46e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1117 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1167
Cdd:pfam00630 40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1754-1818 |
8.25e-04 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 40.74 E-value: 8.25e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1754 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1818
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1754-1821 |
9.03e-03 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 37.97 E-value: 9.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922581632 1754 LNSAQIGQKKGFTIDNINK-SSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEI-YLDHEI 1821
Cdd:smart00557 11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYtVSYTPTEPGDYTVTVkFGGEHI 81
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2698-2792 |
1.29e-28 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 111.54 E-value: 1.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2698 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2777
Cdd:smart00557 1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 2778 EHVPGSPFLVMIVDT 2792
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2695-2785 |
1.50e-22 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 93.89 E-value: 1.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2695 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2774
Cdd:pfam00630 1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
|
90
....*....|.
gi 922581632 2775 WHGEHVPGSPF 2785
Cdd:pfam00630 78 FNGQHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2604-2695 |
9.92e-22 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.90 E-value: 9.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2604 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2682
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 2683 VKGSPFVVHVSLP 2695
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
15-107 |
1.90e-21 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 91.13 E-value: 1.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 15 ASSVSVYGENLRSASVGKTASFMVHAIGAEAKDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLADQR 94
Cdd:smart00557 1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|...
gi 922581632 95 VPDAPFACNVGAP 107
Cdd:smart00557 81 IPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2509-2598 |
1.65e-20 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 88.43 E-value: 1.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2509 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2587
Cdd:smart00557 2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|.
gi 922581632 2588 VKGSPFAVSAD 2598
Cdd:smart00557 81 IPGSPFTVKVG 91
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1420-1503 |
7.54e-19 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.42 E-value: 7.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1420 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVC---EGRVPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1494
Cdd:smart00557 1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTgpsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
....*....
gi 922581632 1495 VPGSPFLCQ 1503
Cdd:smart00557 81 IPGSPFTVK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2100-2189 |
1.17e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 83.04 E-value: 1.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2100 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2179
Cdd:smart00557 4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
|
90
....*....|
gi 922581632 2180 SPFKTEVIDP 2189
Cdd:smart00557 84 SPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1174-1267 |
1.78e-18 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 82.65 E-value: 1.78e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1174 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1252
Cdd:smart00557 1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
|
90
....*....|....*
gi 922581632 1253 EVLKNSPFEVNIVDA 1267
Cdd:smart00557 79 EHIPGSPFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2100-2183 |
2.11e-18 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 82.34 E-value: 2.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2100 VRASGDALRKAQRARTARFEVINVEQNrGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2179
Cdd:pfam00630 7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85
|
....
gi 922581632 2180 SPFK 2183
Cdd:pfam00630 86 SPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
304-388 |
1.06e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 80.34 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 304 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 380
Cdd:smart00557 5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*...
gi 922581632 381 PIKVEILP 388
Cdd:smart00557 85 PFTVKVGP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
13-100 |
5.31e-17 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 78.10 E-value: 5.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 13 ADASSVSVYGENLRSASVGKTASFMVHAIGAEAkDISAHVTVPSGGKFPAKVVTLDDVTFQIEWTPKEPGEHSVDVMLAD 92
Cdd:pfam00630 2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80
|
....*...
gi 922581632 93 QRVPDAPF 100
Cdd:pfam00630 81 QHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1331-1420 |
6.26e-17 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 78.03 E-value: 6.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1331 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1406
Cdd:smart00557 1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
|
90
....*....|....
gi 922581632 1407 PVTGSPFTCRAYDP 1420
Cdd:smart00557 80 HIPGSPFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1610-1689 |
1.95e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1610 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1688
Cdd:smart00557 13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
.
gi 922581632 1689 A 1689
Cdd:smart00557 93 A 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
212-297 |
1.99e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 76.87 E-value: 1.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 212 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 291
Cdd:smart00557 3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82
|
....*.
gi 922581632 292 GSPLSV 297
Cdd:smart00557 83 GSPFTV 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1927-2008 |
9.19e-16 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.95 E-value: 9.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1927 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 2006
Cdd:smart00557 12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
|
..
gi 922581632 2007 DP 2008
Cdd:smart00557 92 PA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2285-2372 |
1.47e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 74.18 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2285 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2363
Cdd:smart00557 6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*....
gi 922581632 2364 PFTVNVVDP 2372
Cdd:smart00557 85 PFTVKVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2008-2096 |
3.07e-15 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 73.41 E-value: 3.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2008 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 2084
Cdd:smart00557 1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
|
90
....*....|..
gi 922581632 2085 LSDGPYEVFISH 2096
Cdd:smart00557 81 IPGSPFTVKVGP 92
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1517-1600 |
1.39e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 71.48 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1517 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1595
Cdd:smart00557 11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88
|
....*
gi 922581632 1596 KAYDA 1600
Cdd:smart00557 89 KVGPA 93
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
119-197 |
2.64e-14 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 70.71 E-value: 2.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 119 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 195
Cdd:smart00557 11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90
|
..
gi 922581632 196 ED 197
Cdd:smart00557 91 GP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2285-2366 |
5.72e-14 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 69.63 E-value: 5.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2285 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 2364
Cdd:pfam00630 9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
|
..
gi 922581632 2365 FT 2366
Cdd:pfam00630 88 FK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1597-1681 |
1.20e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 68.47 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1597 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1674
Cdd:pfam00630 1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80
|
....*..
gi 922581632 1675 ISVPGSP 1681
Cdd:pfam00630 81 QHIPGSP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2509-2593 |
1.62e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 68.08 E-value: 1.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2509 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2587
Cdd:pfam00630 5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82
|
....*.
gi 922581632 2588 VKGSPF 2593
Cdd:pfam00630 83 IPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1417-1500 |
2.97e-13 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 67.70 E-value: 2.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1417 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1491
Cdd:pfam00630 1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
....*....
gi 922581632 1492 NEPVPGSPF 1500
Cdd:pfam00630 80 GQHIPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
304-383 |
3.02e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 64.62 E-value: 3.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 304 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 381
Cdd:pfam00630 8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
|
..
gi 922581632 382 IK 383
Cdd:pfam00630 88 FK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2005-2091 |
4.92e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 64.23 E-value: 4.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2005 VLDPSAVRV--IGLKNAPVGVEQQFSVDYTNSGASiASVEVRHGD-QTIPITVKKMKPGQLLCTFTPFVDGPHQVEVIID 2081
Cdd:pfam00630 1 AADASKVKAsgPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
90
....*....|
gi 922581632 2082 GVPLSDGPYE 2091
Cdd:pfam00630 80 GQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
213-294 |
9.36e-12 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 63.08 E-value: 9.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 213 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 292
Cdd:pfam00630 7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85
|
..
gi 922581632 293 SP 294
Cdd:pfam00630 86 SP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1171-1261 |
1.89e-11 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 62.31 E-value: 1.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1171 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1249
Cdd:pfam00630 1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
|
90
....*....|..
gi 922581632 1250 FNKEVLKNSPFE 1261
Cdd:pfam00630 78 FNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1344-1414 |
1.18e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 60.00 E-value: 1.18e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1344 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1414
Cdd:pfam00630 18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1517-1594 |
2.68e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 59.22 E-value: 2.68e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581632 1517 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1594
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2206-2279 |
3.78e-10 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 58.77 E-value: 3.78e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581632 2206 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2279
Cdd:smart00557 19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2614-2689 |
4.91e-10 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 58.45 E-value: 4.91e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581632 2614 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2689
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2186-2272 |
1.01e-09 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 57.30 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2186 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 2264
Cdd:pfam00630 1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
|
....*...
gi 922581632 2265 GFQIPGYP 2272
Cdd:pfam00630 80 GQHIPGSP 87
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
119-192 |
2.41e-09 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 56.53 E-value: 2.41e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 119 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 192
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
2391-2467 |
3.60e-09 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 56.07 E-value: 3.60e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581632 2391 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2467
Cdd:smart00557 15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
2369-2459 |
2.53e-08 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 53.45 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 2369 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2448
Cdd:pfam00630 1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
|
90
....*....|.
gi 922581632 2449 SIYLYWNELPV 2459
Cdd:pfam00630 73 TVSVKFNGQHI 83
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1930-2001 |
1.32e-07 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 51.52 E-value: 1.32e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1930 IVGEQTELKILIdSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPF 2001
Cdd:pfam00630 18 VVGKPAEFTVDT-RDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1842-1905 |
5.01e-07 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 49.91 E-value: 5.01e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1842 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1905
Cdd:smart00557 16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1842-1906 |
1.87e-06 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 48.05 E-value: 1.87e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1842 AGQKYSFDVNSDD-KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPIG 1906
Cdd:pfam00630 19 VGKPAEFTVDTRDaGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIP 84
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
759-1181 |
1.86e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 759 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 838
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 839 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 915
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 916 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV--------- 986
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakka 1670
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 987 -----------KSEDDKILAKHGFTRKPEPSIEIqepvtEQIRDDVVETAIAPEvPLRPVEELPHSPAPSSRSTPATTPK 1055
Cdd:PTZ00121 1671 eedkkkaeeakKAEEDEKKAAEALKKEAEEAKKA-----EELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKK 1744
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1056 LSAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKS 1135
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDI 1803
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 922581632 1136 SSKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1181
Cdd:PTZ00121 1804 FDNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1087-1174 |
5.52e-05 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 44.13 E-value: 5.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581632 1087 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1165
Cdd:smart00557 17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84
|
....*....
gi 922581632 1166 PFAVRVYDA 1174
Cdd:smart00557 85 PFTVKVGPA 93
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1117-1167 |
6.46e-04 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 41.12 E-value: 6.46e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 922581632 1117 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1167
Cdd:pfam00630 40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
|
|
| Filamin |
pfam00630 |
Filamin/ABP280 repeat; |
1754-1818 |
8.25e-04 |
|
Filamin/ABP280 repeat;
Pssm-ID: 395505 Cd Length: 89 Bit Score: 40.74 E-value: 8.25e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581632 1754 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1818
Cdd:pfam00630 14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
|
|
| IG_FLMN |
smart00557 |
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ... |
1754-1821 |
9.03e-03 |
|
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Pssm-ID: 214720 [Multi-domain] Cd Length: 93 Bit Score: 37.97 E-value: 9.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922581632 1754 LNSAQIGQKKGFTIDNINK-SSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEI-YLDHEI 1821
Cdd:smart00557 11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYtVSYTPTEPGDYTVTVkFGGEHI 81
|
|
| |
