|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
32-453 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 753.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KNvqKGKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQQRqeqAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFDGF 191
Cdd:pfam00709 81 EL--EERGID-VPDRLFISDRAHLILPYHKALDGLREEAR---GKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERFKVLANQYKSIYPTL---EIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGTYPF 268
Cdd:pfam00709 154 REKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPY 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 269 VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKY 348
Cdd:pfam00709 233 VTSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 349 AHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQNY 428
Cdd:pfam00709 313 AVRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKY 392
|
410 420
....*....|....*....|....*
gi 31560737 429 VRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:pfam00709 393 VEFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
30-453 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 670.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEE 109
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 110 AEKNvqKGKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQqrqeqagKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFD 189
Cdd:smart00788 81 IEEL--EAKGVD-VKDRLFISDRAHLILPYHIALDKAREK-------ARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 GFSERFKVLANQY----KSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGT 265
Cdd:smart00788 150 VLREKLEELLDYKnfllKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 266 YPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVS 345
Cdd:smart00788 229 YPYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 346 LKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNA 425
Cdd:smart00788 309 LRYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENA 388
|
410 420
....*....|....*....|....*...
gi 31560737 426 QNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:smart00788 389 KKYIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
27-453 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 637.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 27 GNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGL 106
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 107 FEEAEKNVQKGKGLDGwekRLIISDRAHIVFDFHQAADGIQEQQRQEQaGKNLGTTKKGIGPVYSSKAARSGLRMCDLVs 186
Cdd:PTZ00350 91 LEEIEQLTKKGINLLG---RLYISDRAHLVFDLHQAIDGIQESEKGKG-GTQIGTTKRGIGPCYSTKASRTGLRVGDLL- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 187 DFDGFSERFKVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGTY 266
Cdd:PTZ00350 166 NFETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 267 PFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSL 346
Cdd:PTZ00350 245 PYVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPAL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 347 KYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGET--IPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVN 424
Cdd:PTZ00350 325 RYVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGleIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPEN 404
|
410 420
....*....|....*....|....*....
gi 31560737 425 AQNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:PTZ00350 405 AQKYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
30-455 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 637.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEE 109
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 110 AEKnVQKgKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQQRqeqAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFD 189
Cdd:COG0104 81 IDG-LEA-RGVD-VRSRLRISERAHLILPYHRALDKAREEAR---GKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 GFSERFKVLANQY----KSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALH-GppKKILVEGANAALLDIDFG 264
Cdd:COG0104 154 VLREKLEELLEYKnfllEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 265 TYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLV 344
Cdd:COG0104 232 TYPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 345 SLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVN 424
Cdd:COG0104 312 ALRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPEN 391
|
410 420 430
....*....|....*....|....*....|.
gi 31560737 425 AQNYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:COG0104 392 ARAYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
29-453 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 534.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 29 RVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFE 108
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 109 EAEKNVQKGKgldGWEKRLIISDRAHIVFDFHQAADGIQEQQRQeqaGKNLGTTKKGIGPVYSSKAARSGLRMCDlvsdf 188
Cdd:cd03108 81 EIEELEKKGI---DVKGRLLISDRAHLVFPYHQELDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD----- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 189 dgfserfkvlanqyksiyptleidiegelqqlkgymerikPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGTYPF 268
Cdd:cd03108 150 ----------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPY 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 269 VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKY 348
Cdd:cd03108 189 VTSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRY 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 349 AHMINGFTALALTKLDildmfteikvgvaykldgetiphfpanqevlnkvevqyktlpgwntdisnartfkelpVNAQNY 428
Cdd:cd03108 269 AVRINGLTELALTKLD----------------------------------------------------------VNAQKY 290
|
410 420
....*....|....*....|....*
gi 31560737 429 VRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:cd03108 291 IERIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
32-455 |
1.48e-180 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 510.94 E-value: 1.48e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KNVQKGKGLdgwEKRLIISDRAHIVFDFHQAADGIQEQQrqeQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDfDGF 191
Cdd:TIGR00184 81 YLEKRGISV---RDRLFVSYRCHLILPYHKKLDKAREKS---KLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERFK----VLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGTYP 267
Cdd:TIGR00184 154 AEKAKnileYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 268 FVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLK 347
Cdd:TIGR00184 233 YVTSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAAR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 348 YAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQN 427
Cdd:TIGR00184 313 YACRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKK 392
|
410 420
....*....|....*....|....*...
gi 31560737 428 YVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:TIGR00184 393 YIERIEELTGVPVTIISTGPEREQTIDL 420
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
30-305 |
1.13e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.69 E-value: 1.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQ-GGNNAGHTVVVD-SVEYDFHLLPSGIINPNVTA-FIGNGVVIHLPGL 106
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIVSPPLKQvLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 107 FEE---AEKNVQKGKgldgweKRLIIsdrahivfdfHQAADGIQEQQRQEQAGK---NLGTTKKGIGPVYSSKAARSGLR 180
Cdd:NF038379 81 REEieeLEDAGHDVG------KRLLI----------HEQATVIELHKHVEEEAGpmtKIGSTKKGIGAARAAKIRRNPST 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 181 MCDLVSDFDGFSERFKvlanqyksiypTLEIDIEGELqqlkgymerikpmvkdgvYFLYEALHGPPKKILVEGANAALLD 260
Cdd:NF038379 145 LGDAEGDFGEGAVRDQ-----------PWEIAERVVD------------------NALYDFALQAAERIQIEGTQGYSLG 195
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 31560737 261 IDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGE--VYGVVKAYTTRVG 305
Cdd:NF038379 196 LHAGFYPYCTSRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVA 242
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
32-453 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 753.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KNvqKGKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQQRqeqAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFDGF 191
Cdd:pfam00709 81 EL--EERGID-VPDRLFISDRAHLILPYHKALDGLREEAR---GKKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERFKVLANQYKSIYPTL---EIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGTYPF 268
Cdd:pfam00709 154 REKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEG-KKILFEGAQGTLLDIDHGTYPY 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 269 VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKY 348
Cdd:pfam00709 233 VTSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 349 AHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQNY 428
Cdd:pfam00709 313 AVRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKY 392
|
410 420
....*....|....*....|....*
gi 31560737 429 VRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:pfam00709 393 VEFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
30-453 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 670.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEE 109
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 110 AEKNvqKGKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQqrqeqagKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFD 189
Cdd:smart00788 81 IEEL--EAKGVD-VKDRLFISDRAHLILPYHIALDKAREK-------ARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 GFSERFKVLANQY----KSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGT 265
Cdd:smart00788 150 VLREKLEELLDYKnfllKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAG-KKVLFEGAQGTLLDIDHGT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 266 YPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVS 345
Cdd:smart00788 229 YPYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 346 LKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNA 425
Cdd:smart00788 309 LRYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENA 388
|
410 420
....*....|....*....|....*...
gi 31560737 426 QNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:smart00788 389 KKYIERIEELVGVPVSIISTGPDREQTI 416
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
27-453 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 637.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 27 GNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGL 106
Cdd:PTZ00350 11 KSKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 107 FEEAEKNVQKGKGLDGwekRLIISDRAHIVFDFHQAADGIQEQQRQEQaGKNLGTTKKGIGPVYSSKAARSGLRMCDLVs 186
Cdd:PTZ00350 91 LEEIEQLTKKGINLLG---RLYISDRAHLVFDLHQAIDGIQESEKGKG-GTQIGTTKRGIGPCYSTKASRTGLRVGDLL- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 187 DFDGFSERFKVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGTY 266
Cdd:PTZ00350 166 NFETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIK-EGKRVLVEGANATMLDIDFGTY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 267 PFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSL 346
Cdd:PTZ00350 245 PYVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPAL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 347 KYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGET--IPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVN 424
Cdd:PTZ00350 325 RYVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGleIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPEN 404
|
410 420
....*....|....*....|....*....
gi 31560737 425 AQNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:PTZ00350 405 AQKYVLFIEELLGVPIVWIGVGPNRENMI 433
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
30-455 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 637.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEE 109
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 110 AEKnVQKgKGLDgWEKRLIISDRAHIVFDFHQAADGIQEQQRqeqAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFD 189
Cdd:COG0104 81 IDG-LEA-RGVD-VRSRLRISERAHLILPYHRALDKAREEAR---GKKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 GFSERFKVLANQY----KSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALH-GppKKILVEGANAALLDIDFG 264
Cdd:COG0104 154 VLREKLEELLEYKnfllEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKaG--KKVLFEGAQGTLLDIDHG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 265 TYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLV 344
Cdd:COG0104 232 TYPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 345 SLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVN 424
Cdd:COG0104 312 ALRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPEN 391
|
410 420 430
....*....|....*....|....*....|.
gi 31560737 425 AQNYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:COG0104 392 ARAYVERIEELLGVPISIVSVGPDREQTIVR 422
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
29-455 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 617.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 29 RVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFE 108
Cdd:PRK01117 2 KNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 109 EAEKnvQKGKGLDGwEKRLIISDRAHIVFDFHQAADGIQEQQRqeqaGKN-LGTTKKGIGPVYSSKAARSGLRMCDLVsD 187
Cdd:PRK01117 82 EIDE--LEARGVDV-RERLRISERAHLILPYHRALDKAREKAR----GKKkIGTTGRGIGPAYEDKVARRGIRVGDLL-D 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 188 FDGFSERFKVLANQY----KSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALH-GppKKILVEGANAALLDID 262
Cdd:PRK01117 154 PETFAEKLEENLEYKnfllTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKaG--KRVLFEGAQGTLLDID 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 263 FGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLD 342
Cdd:PRK01117 232 HGTYPFVTSSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 343 LVSLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELP 422
Cdd:PRK01117 312 AVALRYAVRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLP 391
|
410 420 430
....*....|....*....|....*....|...
gi 31560737 423 VNAQNYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:PRK01117 392 ENARKYIKRIEELTGVPISIISTGPDRDQTIIL 424
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
30-453 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 584.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVV-VDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFE 108
Cdd:PLN02513 4 VSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGLFE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 109 EAEKNVQKGKGLDGwekRLIISDRAHIVFDFHQAADGIQEQqrqEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLvSDF 188
Cdd:PLN02513 84 EIDGLESNGVSCEG---RLLVSDRAHLLFDFHQEVDGLREA---ELAGSKIGTTKRGIGPAYSSKATRNGLRVGDL-RHM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 189 DGFSERFKVLANQYKSIYPTLEID---IEGELQQLKGYMERIKPMVKDGVYFLYEAlHGPPKKILVEGANAALLDIDFGT 265
Cdd:PLN02513 157 DTFAEKLRELLADAAARFEGFEYDasmVEEEVEAYKKFAERLEPFITDTVHYLNEA-IQAGKKILVEGAQATMLDIDFGT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 266 YPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVS 345
Cdd:PLN02513 236 YPFVTSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 346 LKYAHMINGFTALALTKLDILDMFTEIKVGVAYKL-DGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVN 424
Cdd:PLN02513 316 LKYSCQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAA 395
|
410 420
....*....|....*....|....*....
gi 31560737 425 AQNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:PLN02513 396 AQAYVERIEELVGVPVHYIGVGPGRDALI 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
29-453 |
0e+00 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 534.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 29 RVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFE 108
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 109 EAEKNVQKGKgldGWEKRLIISDRAHIVFDFHQAADGIQEQQRQeqaGKNLGTTKKGIGPVYSSKAARSGLRMCDlvsdf 188
Cdd:cd03108 81 EIEELEKKGI---DVKGRLLISDRAHLVFPYHQELDGLEEKERG---GKKIGTTKRGIGPAYADKAARTGIRVGD----- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 189 dgfserfkvlanqyksiyptleidiegelqqlkgymerikPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGTYPF 268
Cdd:cd03108 150 ----------------------------------------PYVVDTVELLNEALK-AGKKVLFEGAQGTLLDIDFGTYPY 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 269 VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKY 348
Cdd:cd03108 189 VTSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRY 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 349 AHMINGFTALALTKLDildmfteikvgvaykldgetiphfpanqevlnkvevqyktlpgwntdisnartfkelpVNAQNY 428
Cdd:cd03108 269 AVRINGLTELALTKLD----------------------------------------------------------VNAQKY 290
|
410 420
....*....|....*....|....*
gi 31560737 429 VRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:cd03108 291 IERIEELLGVPITYISVGPDREQTI 315
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
32-455 |
1.48e-180 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 510.94 E-value: 1.48e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KNVQKGKGLdgwEKRLIISDRAHIVFDFHQAADGIQEQQrqeQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDfDGF 191
Cdd:TIGR00184 81 YLEKRGISV---RDRLFVSYRCHLILPYHKKLDKAREKS---KLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDD-EAF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERFK----VLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGTYP 267
Cdd:TIGR00184 154 AEKAKnileYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEG-EKVLFEGAQGTMLDIDYGTYP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 268 FVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLK 347
Cdd:TIGR00184 233 YVTSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAAR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 348 YAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQN 427
Cdd:TIGR00184 313 YACRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKK 392
|
410 420
....*....|....*....|....*...
gi 31560737 428 YVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:TIGR00184 393 YIERIEELTGVPVTIISTGPEREQTIDL 420
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
32-455 |
5.51e-123 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 363.65 E-value: 5.51e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KNVQKGKGLDGwekRLIISDRAHIVFDFHQAADGIQEQQRqeqaGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDfDGF 191
Cdd:PRK13783 84 ELKEKFPDYSG---RIFISELAHVVLPVHKELDEIIESVR----KNAIGTTKRGIGPAYADKVMRVGVRLADLFDE-EKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERFKVLANQYKSIYpTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEALHgppKKILVEGANAALLDIDFGTYPFVTS 271
Cdd:PRK13783 156 REFLEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKIKDLVVSPVEIKRILEE---KSVLFEGTQGVLLDLDVGTYPYVTS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 272 SNCTVGGVCTGLGMPPQnVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKYAHM 351
Cdd:PRK13783 232 SNCSTTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 352 INGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHfPANQEVLNKVEVQYKTLPGWNTDISnartfkelpVNAQNYVRF 431
Cdd:PRK13783 311 VSGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWKSLED---------KNFLKFVDF 380
|
410 420
....*....|....*....|....
gi 31560737 432 IEDELQIPVKWIGVGKSRESMIQL 455
Cdd:PRK13783 381 IERETGRKIAYISTGPKIEEIVEV 404
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
31-454 |
7.24e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 356.42 E-value: 7.24e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 31 TVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIInPNVTAFIGNGVVIHLPGLFEEA 110
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFL-LDARVLIGPGVVLNPEVLAEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 111 EKNVQKGKGLDGweKRLIISDRAHIVFDFHQAADGIQEQQRQEQagknLGTTKKGIGPVYSSKAARSGLRMCDLVsDFDG 190
Cdd:PRK13786 82 DMLEKHGVKVDA--EKLGIDAKTSIIMPYHIELDGLRESARTEK----IGTTKRGIGFAYIDKIARDEVRMSDLV-DKER 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 191 FSERFKVLANQYKSIYPTLEID--IEGELQQLKGYME---RIKPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGT 265
Cdd:PRK13786 155 LMRRLEELAPQKEKEIKELGGDpsIVRDEALIDKYLElgrQLAPYITDVSYEINKALD-EGKSVLAEGAQGTHLDVIHGT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 266 YPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVS 345
Cdd:PRK13786 234 QKFVTSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 346 LKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPVNA 425
Cdd:PRK13786 314 LKKAIYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENA 393
|
410 420
....*....|....*....|....*....
gi 31560737 426 QNYVRFIEDELQIPVKWIGVGKSRESMIQ 454
Cdd:PRK13786 394 RNYVERLEELMGVPIKYISVGPGREQTFK 422
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
33-450 |
7.60e-118 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 350.65 E-value: 7.60e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 33 VLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHlPGLFEEAEK 112
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVID-PFRFAEERE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 113 NVQKGkgldGWEKRLIISDRAHIVFDFHQAADGiqeqqrqeqaGKN-LGTTKKGIGPVYSSKAARSGLRMCDLvSDFDGF 191
Cdd:PRK13788 85 NLRAG----GLNPKLLISERAHLVLPHHKYVDG----------RKNfVGTTGRGIGPAYSDRARRVGIRFGDL-LDEAVL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 192 SERF-KVLANQYKSIYPTLEIDIEGELQQLKGYMERIKPMVKDGVYFLYEAL-HGppKKILVEGANAALLDIDFGTYPFV 269
Cdd:PRK13788 150 RERVeRLLEAKPNSTREAGWDTVEKALADLAPMREILLPFIADTGSLLREAIrEG--KRVLFEGAQATLLDLNYGTYPYV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 270 TSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRG----REFGVTTGRKRRCGWLDLVS 345
Cdd:PRK13788 228 TSSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 346 LKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGetiphfpanqevlnkvEVQYKTLPGWNtDISNARTFKELPVNA 425
Cdd:PRK13788 308 LKYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWG-DLDGVKSREALPKEA 370
|
410 420
....*....|....*....|....*
gi 31560737 426 QNYVRFIEDELQIPVKWIGVGKSRE 450
Cdd:PRK13788 371 QAYLELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
31-455 |
2.34e-116 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 347.71 E-value: 2.34e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 31 TVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHlPGLFEEA 110
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLD-PLFFIEE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 111 EKNVQKgKGLDGWEKrLIISDRAHIVFDFHQAADGIQEQQRQEQagKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDfdG 190
Cdd:PRK13787 83 CDRLQK-EGFPVKDK-LLLSDACHLLFPYHSQIDSARETTSSQE--HKIGTTKKGIGICYADKMMRTGLRVGDLLDK--S 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 191 FSERFKVL---ANQYKSIYPTLEIDIEGELQQ-LKGYMERIKPMVKDGVYFLYEALHgPPKKILVEGANAALLDIDFGTY 266
Cdd:PRK13787 157 YKRRLKHLvdeKNRELDKLYGMPPVSYNDINDgLKFFLSKVGKNIINTAYYLDTELK-KGKRVLLEGAQGTGLDVDFGTY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 267 PFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSL 346
Cdd:PRK13787 236 PYVTSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEML 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 347 KYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPAnqEVLNKVEVQYKTLPGWNTDISNARTFKELPVNAQ 426
Cdd:PRK13787 316 KHSVRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPS--QGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCK 393
|
410 420
....*....|....*....|....*....
gi 31560737 427 NYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:PRK13787 394 NYISALEKWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
30-455 |
5.76e-111 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 334.80 E-value: 5.76e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVlGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVtAFIGNGVVIHLPGLFEE 109
Cdd:PRK13785 3 VTIV-GSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKI-GVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 110 AEknVQKGKGLDgweKRLIISDRAHIVFDFHQAADGIQEQQRQEQaGKNLGTTKKGIGPVYSSKAARSGLRMCDLVsDFD 189
Cdd:PRK13785 81 ID--ALRERGLD---PDVRVAERAHVILPYHRVLDGIEEEAKSDS-DLEVGTTGRGIGPTYEDKAGRRGVRVGDLL-DPD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 GFSERFKVLANQYKSIYPTL----------EIDIEGELQQLKGYMERIKP--MVKDGVYFLYEALHGPpKKILVEGANAA 257
Cdd:PRK13785 154 VLRDRLEYVVPQKRALAEDVygldasetpeAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDG-DNVMLEGAQGT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 258 LLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNV--GEVYGVVKAYTTRVGIGAFPTE---------------QDNEIGEL 320
Cdd:PRK13785 233 SIDIDHGNYPYVTSSNPTAGGAATGTGLGPTVVgqGEVVGIVKAYLSRVGSGPLPTElggvegdtpdeggrpDEEELATY 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 321 LQTRGREFGVTTGRKRRCGWLDLVSLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIPHFPANQEVLNKVEV 400
Cdd:PRK13785 313 IREEGGEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEP 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 31560737 401 QYKTLPGWNT-DISNART--FKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:PRK13785 393 NFRSFDGWPEvDWAAVAEegYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
32-453 |
1.04e-88 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 276.90 E-value: 1.04e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 32 VVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAE 111
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEEIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 112 KnvQKGKGLDGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQagknLGTTKKGIGPVYSSKAARSGLRMCDLvsdFD-- 189
Cdd:PRK13784 85 R--LQAKGIAISAENLFVSESCTIITSYHKLLDAVRESNTSEK----IGTTGKGIGPAYEDKVSRKGIKFKHL---FDkd 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 190 --------GFSERFKVLANQYKSIYPTLEidieGELQQLKGYMERIKPMVKDGVYFLYEALhGPPKKILVEGANAALLDI 261
Cdd:PRK13784 156 llrsrlaiSLAEKETLFRDLYKVEYPTLE----QEFDKLFALGQKLKQYAADTFSIIDQAI-AAGKNVVYEGAQGVLLDV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 262 DFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWL 341
Cdd:PRK13784 231 DYGTYPFVTSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 342 DLVSLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGETIphFPANQEV-LNKVEVQYKTLPGWNTDisNARTFKE 420
Cdd:PRK13784 311 DLPLLKYSAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI--YCAYPGIdLYKVEPILVEMEPFSID--ETVTKDN 386
|
410 420 430
....*....|....*....|....*....|...
gi 31560737 421 LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMI 453
Cdd:PRK13784 387 MPAALKTYLKTIENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
30-455 |
7.63e-62 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 203.96 E-value: 7.63e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQ--DADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLF 107
Cdd:PRK04293 3 CTIVVGGFFGDEGKGKIIAYLALkdKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 108 EEAEKNVQKGkgldgwekRLIISDRAHIVFDFHqaadgIQEQQRQEQAGKNLGTTKKGIGPVYSSKAarsgLRMCDLVSD 187
Cdd:PRK04293 83 KEVEELNVGG--------RVFVDYRCGIIEEKH-----VEEDRSDEHLSKKIGSTGTGCGPANADRV----LRRLKLAKD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 188 FDgfserfkvlanqyksiyptleidiegELqqlkgymeriKPMVKDGVYFLYEALHGPpKKILVEGANAALLDIDFGTYP 267
Cdd:PRK04293 146 VE--------------------------EL----------EKYLTDVPEEVNEALDRG-ENVLIEGTQGFGLSLYYGTYP 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 268 FVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGEllqTRG-REFGVTTGRKRRCGWLDLVSL 346
Cdd:PRK04293 189 YVTSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAE---KLGlVEYGTVTGRRRRVGPFDFELA 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 347 KYAHMINGFTALALTKLDILDmfteikvgvaykldgetiphfpanqevlnkvevqyktlpgwnTDISNARTFKELPVNAQ 426
Cdd:PRK04293 266 RRAARINGATQIAITKLDKLD------------------------------------------KEAYGVTEYDKLPPEAK 303
|
410 420
....*....|....*....|....*....
gi 31560737 427 NYVRFIEDELQIPVKWIGVGKSRESMIQL 455
Cdd:PRK04293 304 KFIEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
30-305 |
1.13e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.69 E-value: 1.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQ-GGNNAGHTVVVD-SVEYDFHLLPSGIINPNVTA-FIGNGVVIHLPGL 106
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDeGRKFVHRMLPNGIVSPPLKQvLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 107 FEE---AEKNVQKGKgldgweKRLIIsdrahivfdfHQAADGIQEQQRQEQAGK---NLGTTKKGIGPVYSSKAARSGLR 180
Cdd:NF038379 81 REEieeLEDAGHDVG------KRLLI----------HEQATVIELHKHVEEEAGpmtKIGSTKKGIGAARAAKIRRNPST 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 181 MCDLVSDFDGFSERFKvlanqyksiypTLEIDIEGELqqlkgymerikpmvkdgvYFLYEALHGPPKKILVEGANAALLD 260
Cdd:NF038379 145 LGDAEGDFGEGAVRDQ-----------PWEIAERVVD------------------NALYDFALQAAERIQIEGTQGYSLG 195
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 31560737 261 IDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGE--VYGVVKAYTTRVG 305
Cdd:NF038379 196 LHAGFYPYCTSRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVA 242
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
30-311 |
1.53e-13 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 72.78 E-value: 1.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVC--RCQGGNNAGHTVVVDS-VEYDFHLLPSGIINPNVTAFIGNGVVIHlPGL 106
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHPLCTCiaRVNSGENAGHTVYDKAgRKFVFNLAPSGLLLPGKRNYIGPECVMD-PVS 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 107 FEEAEKNVQKGKGLDgWEKRLIISDRAhIVFDFHQAADGIQEQQRQeqagknlgTTKKGIGPVYSSKAARSGLRMCDLVS 186
Cdd:PTZ00351 250 FMEKEIIQLIDAGID-YRDRLFIGNVC-IVTPYHKLLDLLGSAANS--------STLKGMAPVHGSKVMKRGIRLDHIFN 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 187 DFDGFSERFKVLANQYKSIYPT------------LEIDIEGELQ-----------------QLKGYMERIK-----PMVK 232
Cdd:PTZ00351 320 DDETLRKRLEKDMDTYLGLLKVknlsdadvvrlcREENSDGVVRvpdyviafaqakdkvefLVKLYRDRVRhnpdfPARC 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31560737 233 DGVYFLYEA-LHGppKKILVEGANAALL-DIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGE-VYGVVKAY-TTRVGIGA 308
Cdd:PTZ00351 400 DVTYELHAAvLRG--EKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSvVLNVHKAPgSSRVGIGA 477
|
...
gi 31560737 309 FPT 311
Cdd:PTZ00351 478 CPS 480
|
|
| |
