large ribosomal subunit protein uL10 [Mus musculus]
uL10 family ribosomal protein( domain architecture ID 11488073)
uL10 family ribosomal protein is an essential element of the ribosomal GTPase-associated center responsible for the interplay with translational factors during various stages of protein synthesis
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
PTZ00135 | PTZ00135 | 60S acidic ribosomal protein P0; Provisional |
1-275 | 1.67e-139 | |||||
60S acidic ribosomal protein P0; Provisional : Pssm-ID: 240285 [Multi-domain] Cd Length: 310 Bit Score: 396.70 E-value: 1.67e-139
|
|||||||||
Name | Accession | Description | Interval | E-value | |||||
PTZ00135 | PTZ00135 | 60S acidic ribosomal protein P0; Provisional |
1-275 | 1.67e-139 | |||||
60S acidic ribosomal protein P0; Provisional Pssm-ID: 240285 [Multi-domain] Cd Length: 310 Bit Score: 396.70 E-value: 1.67e-139
|
|||||||||
Ribosomal_P0_L10e | cd05795 | Ribosomal protein L10 family, P0 and L10e subfamily; composed of eukaryotic 60S ribosomal ... |
9-182 | 1.54e-99 | |||||
Ribosomal protein L10 family, P0 and L10e subfamily; composed of eukaryotic 60S ribosomal protein P0 and the archaeal P0 homolog, L10e. P0 or L10e forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. The stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu, respectively); however, there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). These eukaryotic and archaeal P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2. Pssm-ID: 240221 [Multi-domain] Cd Length: 175 Bit Score: 290.24 E-value: 1.54e-99
|
|||||||||
RL10P_insert | pfam17777 | Insertion domain in 60S ribosomal protein L10P; This domain is found in prokaryotic and ... |
118-180 | 9.53e-20 | |||||
Insertion domain in 60S ribosomal protein L10P; This domain is found in prokaryotic and archaeal ribosomal L10 protein. Pssm-ID: 465500 [Multi-domain] Cd Length: 71 Bit Score: 81.48 E-value: 9.53e-20
|
|||||||||
RplJ | COG0244 | Ribosomal protein L10 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L10 ... |
38-94 | 1.87e-04 | |||||
Ribosomal protein L10 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L10 is part of the Pathway/BioSystem: Ribosome 50S subunit Pssm-ID: 440014 Cd Length: 172 Bit Score: 41.21 E-value: 1.87e-04
|
|||||||||
Name | Accession | Description | Interval | E-value | |||||
PTZ00135 | PTZ00135 | 60S acidic ribosomal protein P0; Provisional |
1-275 | 1.67e-139 | |||||
60S acidic ribosomal protein P0; Provisional Pssm-ID: 240285 [Multi-domain] Cd Length: 310 Bit Score: 396.70 E-value: 1.67e-139
|
|||||||||
Ribosomal_P0_L10e | cd05795 | Ribosomal protein L10 family, P0 and L10e subfamily; composed of eukaryotic 60S ribosomal ... |
9-182 | 1.54e-99 | |||||
Ribosomal protein L10 family, P0 and L10e subfamily; composed of eukaryotic 60S ribosomal protein P0 and the archaeal P0 homolog, L10e. P0 or L10e forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. The stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu, respectively); however, there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). These eukaryotic and archaeal P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2. Pssm-ID: 240221 [Multi-domain] Cd Length: 175 Bit Score: 290.24 E-value: 1.54e-99
|
|||||||||
PTZ00240 | PTZ00240 | 60S ribosomal protein P0; Provisional |
1-259 | 1.68e-67 | |||||
60S ribosomal protein P0; Provisional Pssm-ID: 140267 [Multi-domain] Cd Length: 323 Bit Score: 214.06 E-value: 1.68e-67
|
|||||||||
rplP0 | PRK04019 | acidic ribosomal protein P0; Validated |
9-270 | 6.03e-50 | |||||
acidic ribosomal protein P0; Validated Pssm-ID: 179712 [Multi-domain] Cd Length: 330 Bit Score: 168.89 E-value: 6.03e-50
|
|||||||||
Ribosomal_L10_P0 | cd00379 | Ribosomal protein L10 family; composed of the large subunit ribosomal protein called L10 in ... |
9-181 | 5.54e-28 | |||||
Ribosomal protein L10 family; composed of the large subunit ribosomal protein called L10 in bacteria, P0 in eukaryotes, and L10e in archaea, as well as uncharacterized P0-like eukaryotic proteins. In all three kingdoms, L10 forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein and forms the base of the L7/L12 stalk, while the extended C-terminal helix binds to two or three dimers of the NTD of L7/L12 (L7 and L12 are identical except for an acetylated N-terminus). The L7/L12 stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu, respectively); however, there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). Some eukaryotic P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2. Pssm-ID: 238222 [Multi-domain] Cd Length: 155 Bit Score: 106.11 E-value: 5.54e-28
|
|||||||||
RL10P_insert | pfam17777 | Insertion domain in 60S ribosomal protein L10P; This domain is found in prokaryotic and ... |
118-180 | 9.53e-20 | |||||
Insertion domain in 60S ribosomal protein L10P; This domain is found in prokaryotic and archaeal ribosomal L10 protein. Pssm-ID: 465500 [Multi-domain] Cd Length: 71 Bit Score: 81.48 E-value: 9.53e-20
|
|||||||||
Ribosomal_L10 | pfam00466 | Ribosomal protein L10; |
1-102 | 2.89e-19 | |||||
Ribosomal protein L10; Pssm-ID: 459822 [Multi-domain] Cd Length: 99 Bit Score: 81.05 E-value: 2.89e-19
|
|||||||||
Ribosomal_P0_like | cd05796 | Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized ... |
9-167 | 1.22e-15 | |||||
Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be involved in mRNA decay. P0 forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. It occupies the L7/L12 stalk of the ribosome. The stalk is known to contain the binding site for elongation factors EF-G and EF-Tu; however, there is disagreement as to whether or not P0 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, P0 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). Some eukaryotic P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2. Pssm-ID: 240222 [Multi-domain] Cd Length: 163 Bit Score: 73.00 E-value: 1.22e-15
|
|||||||||
Ribosomal_L10 | cd05797 | Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and ... |
16-94 | 2.46e-05 | |||||
Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein and forms the base of the L7/L12 stalk, while the extended C-terminal helix binds to two or three dimers of the NTD of L7/L12 (L7 and L12 are identical except for an acetylated N-terminus). The L7/L12 stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu, respectively); however, there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). These bacteria and eukaryotic sequences have no additional C-terminal domain, present in other eukaryotic and archaeal orthologs. Pssm-ID: 240223 Cd Length: 157 Bit Score: 43.65 E-value: 2.46e-05
|
|||||||||
RplJ | COG0244 | Ribosomal protein L10 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L10 ... |
38-94 | 1.87e-04 | |||||
Ribosomal protein L10 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L10 is part of the Pathway/BioSystem: Ribosome 50S subunit Pssm-ID: 440014 Cd Length: 172 Bit Score: 41.21 E-value: 1.87e-04
|
|||||||||
Ribosomal_60s | pfam00428 | 60s Acidic ribosomal protein; This family includes archaebacterial L12, eukaryotic P0, P1 and ... |
231-316 | 3.44e-03 | |||||
60s Acidic ribosomal protein; This family includes archaebacterial L12, eukaryotic P0, P1 and P2. Pssm-ID: 459808 Cd Length: 87 Bit Score: 36.08 E-value: 3.44e-03
|
|||||||||
rplJ | PRK00099 | 50S ribosomal protein L10; Reviewed |
38-94 | 3.53e-03 | |||||
50S ribosomal protein L10; Reviewed Pssm-ID: 234632 Cd Length: 172 Bit Score: 37.81 E-value: 3.53e-03
|
|||||||||
Blast search parameters | ||||
|