|
Name |
Accession |
Description |
Interval |
E-value |
| PACT_coil_coil |
pfam10495 |
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ... |
2701-2779 |
1.04e-26 |
|
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.
Pssm-ID: 463115 Cd Length: 77 Bit Score: 105.37 E-value: 1.04e-26
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 2701 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 2779
Cdd:pfam10495 2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1086-1661 |
3.27e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.21 E-value: 3.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1086 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 1164
Cdd:COG1196 219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1165 VLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQL 1244
Cdd:COG1196 299 RLEQDIARLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1245 AALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELV 1324
Cdd:COG1196 372 AELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1325 IKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTVSRSGLDEAGCP 1402
Cdd:COG1196 442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGVKAALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1403 MLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQKDKAEEIEQLHE 1469
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAALAAALARGAIGA 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1470 VIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLANQAHGHSQALEALQQ 1547
Cdd:COG1196 600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRRELLAALLEAEA 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1548 RLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshsleleAILLALAHFR 1627
Cdd:COG1196 680 ELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------------ELLEELLEEE 745
|
570 580 590
....*....|....*....|....*....|....
gi 294862457 1628 HALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 1661
Cdd:COG1196 746 ELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
118-584 |
1.13e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 118 LELEALRLSLNNMHTAQLELTQA-NLQKEKETALTELREMLNGRRAQELALLQSRQQcELELLREQHAREKEEMAlrsgq 196
Cdd:COG1196 281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELE----- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 197 EAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQsemeglQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ------LEELEEAEEALLERLERLEEELEELEE 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 277 SLKNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLEsMKTNREE 356
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEG 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLEST 436
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 437 EISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEER 516
Cdd:COG1196 586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLL 584
Cdd:COG1196 666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
133-647 |
3.17e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 3.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 133 AQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEM-------------ALRSGQEAA 199
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeeakkkadaAKKKAEEAK 1342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 200 ELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELE----------KIFQ 269
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADelkkaaaakkKADE 1422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 270 AKHEAEVSLKNLEAQHQAAIKKLQEDLQ--SEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQL 347
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKkkAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 348 ---ESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR 424
Cdd:PTZ00121 1503 kkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 425 LQEAREdsLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQV---------------KLSKAEEKIQ 489
Cdd:PTZ00121 1583 AEEAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVeqlkkkeaeekkkaeELKKAEEENK 1660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 490 QMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESsmrhlqdQQAAQILDLERSLMEQQG 569
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAE 1733
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 570 HLRQLEQELTRDdllpcsqcGQEPAMAQEEKNGALLREKEDCAlqllmAQNRFLEERKEIMEKFAKEQDAFLRDAQEK 647
Cdd:PTZ00121 1734 EAKKEAEEDKKK--------AEEAKKDEEEKKKIAHLKKEEEK-----KAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1068-1386 |
4.00e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.86 E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1068 VEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQlilELEDLRK 1147
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEE 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1148 QLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQS----EKDRATLLSQMRVLESELEDQ 1223
Cdd:TIGR02169 745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRL 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1224 lvqHRGCAQLAEEVATLKQQLAALDkhlrSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAarprppgprDSQCVQLD 1303
Cdd:TIGR02169 825 ---TLEKEYLEKEIQELQEQRIDLK----EQIKSIEKEIENLNGKKEELEEELEELEAALRDL---------ESRLGDLK 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1304 EEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEkQKKSMEELKEKEILKQENM 1383
Cdd:TIGR02169 889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAELQRVEEEI 967
|
...
gi 294862457 1384 GDL 1386
Cdd:TIGR02169 968 RAL 970
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2202-2491 |
7.77e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 7.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2202 RRQVELLAYKVEqekcianELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAV 2281
Cdd:COG1196 224 ELEAELLLLKLR-------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2282 LDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQK 2361
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2362 ELQIEASRCEALLAQEKGQLSELQKSLEAERSrslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTR 2441
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEA---EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 294862457 2442 ALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEH 2491
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
510-1186 |
2.12e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 2.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 510 KREAEERLASM------------------------------FLELREKAE----SEKLSIISRFEHRESSMRHLQDQQAA 555
Cdd:COG1196 174 KEEAERKLEATeenlerledilgelerqleplerqaekaerYRELKEELKeleaELLLLKLRELEAELEELEAELEELEA 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 556 QILDLERSLMEQQGHLRQLEQELTRDDLlpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAK 635
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 636 EQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKR- 714
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAa 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 715 HLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKEScHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHI 794
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 795 ENGKGPAADLQGAHQQDPAMALHNEGHLlveDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQD 874
Cdd:COG1196 480 AELLEELAEAAARLLLLLEAEADYEGFL---EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 875 QVAQVRDKvFLLNRELEecRAELEQLQQRRERENQEgttlicmlRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLK 954
Cdd:COG1196 557 EVAAAAIE-YLKAAKAG--RATFLPLDKIRARAALA--------AALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 955 SRISERAgllldheDAADTSDARLAAAALgdmwsdEGLLEIDRTLPEGAETSsvceisshvcesffispentldceqpiR 1034
Cdd:COG1196 626 TLVAARL-------EAALRRAVTLAGRLR------EVTLEGEGGSAGGSLTG---------------------------G 665
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1035 RVYQSLSTAVEGLLEMALDSSKQLEEARQLhrcvEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLL 1114
Cdd:COG1196 666 SRRELLAALLEAEAELEELAERLAEEELEL----EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 1115 EGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQ-------AARELLTLKEEKSVLWNQKETLTNEAKEREAALQE 1186
Cdd:COG1196 742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllAIEEYEELEERYDFLSEQREDLEEARETLEEAIEE 820
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
345-1163 |
2.04e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 345 SQLESMKTN-------REELNGSWDPVLAQASHLE-------ELEHLRSGFAQQQQQERAQHESELEHLrvyfEKKLKDA 410
Cdd:TIGR02168 179 RKLERTRENldrlediLNELERQLKSLERQAEKAErykelkaELRELELALLVLRLEELREELEELQEE----LKEAEEE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 411 EKTYQEDLTVFQQRLQEARedsLESTEISSSCVLPEETSGREGKEPPDpLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ 490
Cdd:TIGR02168 255 LEELTAELQELEEKLEELR---LEVSELEEEIEELQKELYALANEISR-LEQQKQILRERLANLERQLEELEAQLEELES 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 491 MKEEFQKKEAEWELSREELKREAEErLASMFLELREKAESEKLSIISRFEHRES------SMRHLQDQQAAQILDLERSL 564
Cdd:TIGR02168 331 KLDELAEELAELEEKLEELKEELES-LEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 565 MEQQGHLRQLEQELtrddllpcSQCGQEPAMAQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAfLRDA 644
Cdd:TIGR02168 410 ERLEDRRERLQQEI--------EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQA-LDAA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 645 QEKHNHelqllqqGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEIS---ALEKRHLSNLDE 721
Cdd:TIGR02168 481 ERELAQ-------LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 722 LESCYVADVQTIRdEHQQALELLRAELEEQLQKKESCHREMLTQelENLKRQHAEELQSVRDSLRMEMSAqhIENGKGPA 801
Cdd:TIGR02168 554 NLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKN--IEGFLGVAKDLVKFDPKLRKALSY--LLGGVLVV 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 802 ADLQGAHQQdpAMALHNEGHLLVEDGDAVLRSvdaeGLLhqAGPQELGDAHTVEMQKSQAELAkpQELQASQDQVAQVRD 881
Cdd:TIGR02168 629 DDLDNALEL--AKKLRPGYRIVTLDGDLVRPG----GVI--TGGSAKTNSSILERRREIEELE--EKIEELEEKIAELEK 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 882 KVFLLNRELEECRAELEQLQQRRERENQEgttlICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERA 961
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEELSRQ----ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 962 GLLLDHEDAADTSDARLAAAAlgdmwsdEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTL-DCEQPIRRVYQSL 1040
Cdd:TIGR02168 775 EELAEAEAEIEELEAQIEQLK-------EELKALREALDELRAELTLLNEEAANLRERLESLERRIaATERRLEDLEEQI 847
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1041 STAVEGLLEMAL----------DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTA 1110
Cdd:TIGR02168 848 EELSEDIESLAAeieeleelieELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1111 KGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 1163
Cdd:TIGR02168 928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
142-529 |
3.58e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.60 E-value: 3.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 142 LQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQ 221
Cdd:pfam02463 634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 222 DWESERELCLENLRQELSLKHQSEMEGLQSQF-QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA--IKKLQEDLQS 298
Cdd:pfam02463 714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIdEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREktEKLKVEEEKE 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 299 EHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLwSQLESMKTNREELNgswdpvlaqashlEELEHLR 378
Cdd:pfam02463 794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL-ALELKEEQKLEKLA-------------EEELERL 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 379 SGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:pfam02463 860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 459 PLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ-------MKEEFQKKEAEWELSREELKREAEERLASMFLELREKAE 529
Cdd:pfam02463 940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEElgkvnlmAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2191-2504 |
9.37e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 9.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2191 EARGSQREHQLRRQVE-----LLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHackqentSLL 2265
Cdd:TIGR02168 208 QAEKAERYKELKAELRelelaLLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS-------ELE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2266 ESLDKVQQEVLRLRAVLDGKEKELKVVLEELESergkgqalQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQL 2345
Cdd:TIGR02168 281 EEIEELQKELYALANEISRLEQQKQILRERLAN--------LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2346 CVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALqherlltEQLSRNSQEACARQET 2425
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL-------ERLEDRRERLQQEIEE 425
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 2426 QVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKERELEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:TIGR02168 426 LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE--LEEAEQALDAAERELAQLQARLDSLERLQENLE 502
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
156-430 |
2.41e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 2.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 156 MLNGRRAQELALLQSRQQcELELLREQhaREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE---SERELCLE 232
Cdd:TIGR02168 660 VITGGSAKTNSSILERRR-EIEELEEK--IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqiSALRKDLA 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 233 NLRQ--ELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEA---QHQAAIKKLQEDLQSEHCQY--LQ 305
Cdd:TIGR02168 737 RLEAevEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAELtlLN 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 306 DLEQKFREKEKAKELELETLQASYEDLKAQS---QEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFA 382
Cdd:TIGR02168 817 EEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 294862457 383 QQQQQERAQHESELEHLRVYFEkKLKDAEKTYQEDLTVFQQRLQEARE 430
Cdd:TIGR02168 897 EELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQE 943
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
485-1370 |
2.28e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.44 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 485 EEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSL 564
Cdd:pfam02463 194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKE 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 565 MEQQghLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKedcaLQLLMAQNRFLEERKEimekfaKEQDAFLRDA 644
Cdd:pfam02463 274 NKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK----LKESEKEKKKAEKELK------KEKEEIEELE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 645 QEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELES 724
Cdd:pfam02463 342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 725 CYVADVQTIRDEHQQALELLRAELEEQLQKKEschremLTQELENLKRQHAEELQSVRdslrmemsAQHIENGKGPAADL 804
Cdd:pfam02463 422 KEEKKEELEILEEEEESIELKQGKLTEEKEEL------EKQELKLLKDELELKKSEDL--------LKETQLVKLQEQLE 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 805 QGAHQQDPAMALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVemqksqAELAKPQELQASQDQVAQVRDKVF 884
Cdd:pfam02463 488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA------VENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 885 llnrELEECRAELEQLQQRRERENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLL 964
Cdd:pfam02463 562 ----ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 965 LDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAV 1044
Cdd:pfam02463 638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1045 EGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALEL-HTAKGLLEGFKVEKVD 1123
Cdd:pfam02463 718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEReKTEKLKVEEEKEEKLK 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1124 LQEALGKKEESEQQLILEledlrkQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqSE 1203
Cdd:pfam02463 798 AQEEELRALEEELKEEAE------LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL----------EE 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1204 KDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIqRLEGQL 1283
Cdd:pfam02463 862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE-EEPEEL 940
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1284 RQAARPRPPGPRDSqcvQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1363
Cdd:pfam02463 941 LLEEADEKEKEENN---KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
|
....*..
gi 294862457 1364 KQKKSME 1370
Cdd:pfam02463 1018 RLKEFLE 1024
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2175-2494 |
8.57e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.68 E-value: 8.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2175 QNQEKLQQLCAALTSTEARGSQREHQLRRQVELlayKVEQEKCIANELQKT--LSKEQETASDVRKRLVVEQNAVQDLKS 2252
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEA---KKAEEKKKADELKKAeeLKKAEEKKKAEEAKKAEEDKNMALRKA 1583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2253 ELhaCKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESErgkgqalqAQQEEQQLRYLQREGQSSRALEELK 2332
Cdd:PTZ00121 1584 EE--AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA--------EEEKKKVEQLKKKEAEEKKKAEELK 1653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2333 LSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALL--AQEKGQLSELQKSLEAERSRSLELSEALQHERLLTE 2410
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2411 QLSRNSQEacarqetqvqhallRKLKAEKTRALELEAmlEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDE 2490
Cdd:PTZ00121 1734 EAKKEAEE--------------DKKKAEEAKKDEEEK--KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
|
....
gi 294862457 2491 HKIE 2494
Cdd:PTZ00121 1798 KKIK 1801
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
2197-2504 |
9.87e-06 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 51.29 E-value: 9.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2197 REHQLRRQVELLAYKVEQEKCIaNELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVL 2276
Cdd:pfam07111 312 REKVFALMVQLKAQDLEHRDSV-KQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARR 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2277 RLRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLR---------YLQREGQSSRALEELKLSLEKQLAQ------ 2341
Cdd:pfam07111 391 RQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARipslsnrlsYAVRKVHTIKGLMARKVALAQLRQEscpppp 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2342 -----NNQLCVALKHERAAKDNLQKELQI-------EASRCEALLAQEKGQLSELQKSLEAERSRS--------LELSEA 2401
Cdd:pfam07111 471 pappvDADLSLELEQLREERNRLDAELQLsahliqqEVGRAREQGEAERQQLSEVAQQLEQELQRAqeslasvgQQLEVA 550
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2402 LQHERLLTEQLSRNSQEACARQETQVQhALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERE 2481
Cdd:pfam07111 551 RQGQQESTEEAASLRQELTQQQEIYGQ-ALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERN 629
|
330 340
....*....|....*....|...
gi 294862457 2482 LEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:pfam07111 630 QELRRLQDEARKEEGQRLARRVQ 652
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1053-1376 |
2.39e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1053 DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQ-KQQELLERLREESAAKDRLALELHTAKgllEGFKVEKVDLQEALGKK 1131
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLY 1601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1132 EESEQqliLELEDLRKQLQQ--AARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSE-KDRAT 1208
Cdd:PTZ00121 1602 EEEKK---MKAEEAKKAEEAkiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdKKKAE 1678
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1209 LLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQ---RQFMDDQAAEREHEREEFQQEIQRLEGQLRQ 1285
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1286 AARPRPPGPRDSQCVQLDEEVeLLQEKLREKLDGFNELVIK--KDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1363
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEA-VIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837
|
330
....*....|...
gi 294862457 1364 KQKKSMEELKEKE 1376
Cdd:PTZ00121 1838 SKNMQLEEADAFE 1850
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
203-532 |
4.94e-05 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 48.86 E-value: 4.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 203 EKLRSEMEKNAQT--------IETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKvelekifqaKHEA 274
Cdd:NF033838 72 SEIQKSLDKRKHTqnvalnkkLSDIKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPG---------KKVA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 275 EVSLKNLEAQHQAAIKKlQEDLQSEHCQYLQDLEQKFREKE-KAKELELETLQAsyEDLKAQSQEEIRLLWSQLESMKtn 353
Cdd:NF033838 143 EATKKVEEAEKKAKDQK-EEDRRNYPTNTYKTLELEIAESDvEVKKAELELVKE--EAKEPRDEEKIKQAKAKVESKK-- 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 354 reelngswdpvlAQASHLEELEHLRsgfaqqqqqERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR--LQE-ARE 430
Cdd:NF033838 218 ------------AEATRLEKIKTDR---------EKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRgvLGEpATP 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 431 DSLESTEISSSCVLPEETsgregkePPDPlDLQLGQpKVQESlvedcQVKLSKAEEKIQQMKEEFQK------------- 497
Cdd:NF033838 277 DKKENDAKSSDSSVGEET-------LPSP-SLKPEK-KVAEA-----EKKVEEAKKKAKDQKEEDRRnyptntyktlele 342
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 294862457 498 --------KEAEWELSREELKR-EAEERLAsmflELREKAESEK 532
Cdd:NF033838 343 iaesdvkvKEAELELVKEEAKEpRNEEKIK----QAKAKVESKK 382
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1069-1374 |
1.00e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.30 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1069 EREFRHRNEEMAQAMQKQQELLERLREEsaakdrlaleLHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQ 1148
Cdd:pfam12128 599 EEELRERLDKAEEALQSAREKQAAAEEQ----------LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDK 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1149 LQQAarelltLKEEKSVLWNQKETLTNEAKEREAALQEEVEsltrvqwESRKQSEKDRATLLSQMRVLESELEDQLvqhr 1228
Cdd:pfam12128 669 KNKA------LAERKDSANERLNSLEAQLKQLDKKHQAWLE-------EQKEQKREARTEKQAYWQVVEGALDAQL---- 731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1229 gcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPR--DSQCVQLDEEV 1306
Cdd:pfam12128 732 --ALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRR 809
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 294862457 1307 ELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKR----LEETNASIQRQMVQLQEELEKQKKSMEELKE 1374
Cdd:pfam12128 810 PRLATQLSNIERAISEL-------QQQLARLIADTKLrrakLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2072-2297 |
9.76e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 9.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2072 QALSEVTT---DKGEKESLETH-----LTWSEELLRAIQEVFAREQEKAELQPRPYGSNLGDYNSLVQRLEKVIQEQGdp 2143
Cdd:TIGR02169 272 QLLEELNKkikDLGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER-- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2144 qkvqdhlclSDRSSLLAEIQALRAQLRMTHLQNQEKlqqlcaaltSTEARGSQREH-QLRRQVELLAYKVEQEKCIANEL 2222
Cdd:TIGR02169 350 ---------KRRDKLTEEYAELKEELEDLRAELEEV---------DKEFAETRDELkDYREKLEKLKREINELKRELDRL 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2223 QKTLSKEQETASDVR---KRLVVEQNAVQ----DLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEE 2295
Cdd:TIGR02169 412 QEELQRLSEELADLNaaiAGIEAKINELEeekeDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
..
gi 294862457 2296 LE 2297
Cdd:TIGR02169 492 LA 493
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PACT_coil_coil |
pfam10495 |
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ... |
2701-2779 |
1.04e-26 |
|
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.
Pssm-ID: 463115 Cd Length: 77 Bit Score: 105.37 E-value: 1.04e-26
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 2701 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 2779
Cdd:pfam10495 2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1086-1661 |
3.27e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.21 E-value: 3.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1086 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 1164
Cdd:COG1196 219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1165 VLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQL 1244
Cdd:COG1196 299 RLEQDIARLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1245 AALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELV 1324
Cdd:COG1196 372 AELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1325 IKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTVSRSGLDEAGCP 1402
Cdd:COG1196 442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGVKAALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1403 MLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQKDKAEEIEQLHE 1469
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAALAAALARGAIGA 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1470 VIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLANQAHGHSQALEALQQ 1547
Cdd:COG1196 600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRRELLAALLEAEA 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1548 RLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshsleleAILLALAHFR 1627
Cdd:COG1196 680 ELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------------ELLEELLEEE 745
|
570 580 590
....*....|....*....|....*....|....
gi 294862457 1628 HALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 1661
Cdd:COG1196 746 ELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1038-1598 |
6.39e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.89 E-value: 6.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1038 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQEL-------LERLREESAAKDRLALELHTA 1110
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLeqdiarlEERRRELEERLEELEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1111 KGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVES 1190
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1191 LtrvqwesrKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddqaaEREHERE 1270
Cdd:COG1196 409 E--------EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-------ELLEEAA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1271 EFQQEIQRLEGQLRQAArprppgPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNAS 1350
Cdd:COG1196 474 LLEAALAELLEELAEAA------ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1351 IQRQMVQLQEELEKQkksmeelkeKEILKQENMGdllltTVSRSGLDEAgcpmlpQGSSSRGPEAQPDVTERALLQHENE 1430
Cdd:COG1196 548 LQNIVVEDDEVAAAA---------IEYLKAAKAG-----RATFLPLDKI------RARAALAAALARGAIGAAVDLVASD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1431 VVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGG 1510
Cdd:COG1196 608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1511 QALRSELQAAQAAKEVFGQLLANQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMASQIQEFAATLKA 1590
Cdd:COG1196 688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
....*...
gi 294862457 1591 KEAIIEQR 1598
Cdd:COG1196 768 ELERLERE 775
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
118-584 |
1.13e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 118 LELEALRLSLNNMHTAQLELTQA-NLQKEKETALTELREMLNGRRAQELALLQSRQQcELELLREQHAREKEEMAlrsgq 196
Cdd:COG1196 281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELE----- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 197 EAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQsemeglQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ------LEELEEAEEALLERLERLEEELEELEE 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 277 SLKNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLEsMKTNREE 356
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEG 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLEST 436
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 437 EISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEER 516
Cdd:COG1196 586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLL 584
Cdd:COG1196 666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
142-723 |
1.39e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 67.27 E-value: 1.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 142 LQKEKETAL--TELREMLNGRRAQELALlqsrqqcELELLREQHAREKEEMalrsgQEAAELKEKLRSEMEKNAQTIETL 219
Cdd:COG1196 205 LERQAEKAEryRELKEELKELEAELLLL-------KLRELEAELEELEAEL-----EELEAELEELEAELAELEAELEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 220 KQDweserelcLENLRQELSLKHQSEMEgLQSQFQKELSEQKVELEKIfQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSe 299
Cdd:COG1196 273 RLE--------LEELELELEEAQAEEYE-LLAELARLEQDIARLEERR-RELEERLEELEEELAELEEELEELEEELEE- 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 300 hcqyLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELngswdpvLAQASHLEELEHLRS 379
Cdd:COG1196 342 ----LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA-------AELAAQLEELEEAEE 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 380 GfaqqQQQERAQHESELEHLrvyfEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSScVLPEETSGREGKEPPDP 459
Cdd:COG1196 411 A----LLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL-LAELLEEAALLEAALAE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 460 LDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKE-----AEWELSREELKREAEERLASMFLELREKAESEKLS 534
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 535 IIsrfehressmRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKEDCALQ 614
Cdd:COG1196 562 AI----------EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 615 LLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLE 694
Cdd:COG1196 632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711
|
570 580
....*....|....*....|....*....
gi 294862457 695 THVAELQVKHNAEISALEKRHLSNLDELE 723
Cdd:COG1196 712 AEEERLEEELEEEALEEQLEAEREELLEE 740
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
133-647 |
3.17e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 3.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 133 AQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEM-------------ALRSGQEAA 199
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeeakkkadaAKKKAEEAK 1342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 200 ELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELE----------KIFQ 269
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADelkkaaaakkKADE 1422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 270 AKHEAEVSLKNLEAQHQAAIKKLQEDLQ--SEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQL 347
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKkkAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 348 ---ESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR 424
Cdd:PTZ00121 1503 kkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 425 LQEAREdsLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQV---------------KLSKAEEKIQ 489
Cdd:PTZ00121 1583 AEEAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVeqlkkkeaeekkkaeELKKAEEENK 1660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 490 QMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESsmrhlqdQQAAQILDLERSLMEQQG 569
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAE 1733
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 570 HLRQLEQELTRDdllpcsqcGQEPAMAQEEKNGALLREKEDCAlqllmAQNRFLEERKEIMEKFAKEQDAFLRDAQEK 647
Cdd:PTZ00121 1734 EAKKEAEEDKKK--------AEEAKKDEEEKKKIAHLKKEEEK-----KAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
152-784 |
3.98e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 3.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 152 ELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELK----EKLRSEMEKNAQTIETLKQDWESER 227
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKkdaeEAKKAEEERNNEEIRKFEEARMAHF 1265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 228 ELCLENLRQELSLKHQsEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDL 307
Cdd:PTZ00121 1266 ARRQAAIKAEEARKAD-ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA 1344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 308 EQKFREKEKAKELELETLQASYEDLKAQSQEEIRllwsQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQ 387
Cdd:PTZ00121 1345 AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK----KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA 1420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 388 ERAQHESelEHLRVYFEKKLKDAEKTYQEDLtvfQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQP 467
Cdd:PTZ00121 1421 DEAKKKA--EEKKKADEAKKKAEEAKKADEA---KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA 1495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 468 KVQESLVEDCQVKLSKAEE--KIQQMKEEFQKKEAEWELSREELKREAEERLASmflELREKAESEKLSIISRFEH--RE 543
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEakKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD---ELKKAEELKKAEEKKKAEEakKA 1572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 544 SSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTrddllpcsqcGQEPAMAQEEKNGA-LLREKEDCALQLLMAQNRF 622
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK----------AEEAKKAEEAKIKAeELKKAEEEKKKVEQLKKKE 1642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 623 LEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAElQV 702
Cdd:PTZ00121 1643 AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE-EL 1721
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 703 KHNAEISALEKRHLSNLDELESCYVADVQTIRDEH---QQALELLRAELEEQLQKKESCHREMLTQELENLKRQHAEELQ 779
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKkkiAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
|
....*
gi 294862457 780 SVRDS 784
Cdd:PTZ00121 1802 DIFDN 1806
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1068-1386 |
4.00e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.86 E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1068 VEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQlilELEDLRK 1147
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEE 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1148 QLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQS----EKDRATLLSQMRVLESELEDQ 1223
Cdd:TIGR02169 745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRL 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1224 lvqHRGCAQLAEEVATLKQQLAALDkhlrSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAarprppgprDSQCVQLD 1303
Cdd:TIGR02169 825 ---TLEKEYLEKEIQELQEQRIDLK----EQIKSIEKEIENLNGKKEELEEELEELEAALRDL---------ESRLGDLK 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1304 EEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEkQKKSMEELKEKEILKQENM 1383
Cdd:TIGR02169 889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAELQRVEEEI 967
|
...
gi 294862457 1384 GDL 1386
Cdd:TIGR02169 968 RAL 970
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2202-2491 |
7.77e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 7.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2202 RRQVELLAYKVEqekcianELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAV 2281
Cdd:COG1196 224 ELEAELLLLKLR-------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2282 LDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQK 2361
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2362 ELQIEASRCEALLAQEKGQLSELQKSLEAERSrslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTR 2441
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEA---EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 294862457 2442 ALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEH 2491
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
118-631 |
1.15e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 1.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 118 LELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQE 197
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 198 AAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQ-SEMEGLQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196 307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEElEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 277 SLKNLEAQHQAAIKKLQEDLQSEHcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREE 356
Cdd:COG1196 387 ELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQE--DLTVFQQRLQEAREDSL- 433
Cdd:COG1196 466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALa 545
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 434 --------ESTEISSSCV--LPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWE 503
Cdd:COG1196 546 aalqnivvEDDEVAAAAIeyLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 504 LSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDL 583
Cdd:COG1196 626 TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 294862457 584 lpcsqcgQEPAMAQEEKNGALLREKEDCALQLLMAQNRFLEERKEIME 631
Cdd:COG1196 706 -------ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
855-1474 |
1.33e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 1.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 855 EMQKSQAELAKPQ-ELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERenqegttlicmLRADLELAQGEGKALR 933
Cdd:COG1196 247 ELEELEAELEELEaELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-----------LEQDIARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 934 DALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAAlgdmwsdEGLLEIDRTLpegaetssvceiss 1013
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE-------EALLEAEAEL-------------- 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1014 hvcesffispentldceqpirrvyQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERL 1093
Cdd:COG1196 375 ------------------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1094 REESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETL 1173
Cdd:COG1196 431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1174 TNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATL------KQQLAAL 1247
Cdd:COG1196 511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpldkirARAALAA 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1248 DKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKK 1327
Cdd:COG1196 591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1328 DFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAgcpMLPQG 1407
Cdd:COG1196 671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL---EEEEL 747
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294862457 1408 SSSRGPEAQPDVTERALLQHENEVVHRRNSE--------IDELKSLIENLQENQRQLQkDKAEEIEQLHEVIEKL 1474
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEAlgpvnllaIEEYEELEERYDFLSEQRE-DLEEARETLEEAIEEI 821
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
860-1478 |
1.46e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 860 QAELAKPQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEGTTLIC-MLRADLELAQGEGKALRDALRR 938
Cdd:TIGR02168 372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkLEEAELKELQAELEELEEELEE 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 939 LLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAalgdmwsdEGLLEIDRTLPEG--AETSSVCEISSHV- 1015
Cdd:TIGR02168 452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL--------ERLQENLEGFSEGvkALLKNQSGLSGILg 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1016 CESFFISPENTLDceqpirrvyQSLSTAVEGLLEMALDSSKQ--------LEEARQ-------LHRCVEREFRHRNEEMA 1080
Cdd:TIGR02168 524 VLSELISVDEGYE---------AAIEAALGGRLQAVVVENLNaakkaiafLKQNELgrvtflpLDSIKGTEIQGNDREIL 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1081 QAMQKQQELLERLrEESAAKDRLALElhtakGLLEGFKVEKvDLQEALG-KKEESEQQLILELED--------LRKQLQQ 1151
Cdd:TIGR02168 595 KNIEGFLGVAKDL-VKFDPKLRKALS-----YLLGGVLVVD-DLDNALElAKKLRPGYRIVTLDGdlvrpggvITGGSAK 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1152 AARELLTLKEEKSVLWNQKETLTNEAKEREAALQEeveslTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRG-C 1230
Cdd:TIGR02168 668 TNSSILERRREIEELEEKIEELEEKIAELEKALAE-----LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeV 742
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1231 AQLAEEVATLKQQLAALDKhlrsQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQ 1310
Cdd:TIGR02168 743 EQLEERIAQLSKELTELEA----EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---------ELKALREALDELR 809
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1311 EKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEK-EILKQENMGDLLLT 1389
Cdd:TIGR02168 810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEEAL 889
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1390 TVSRSGLDEAgcpmlpqgSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHE 1469
Cdd:TIGR02168 890 ALLRSELEEL--------SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEN 961
|
....*....
gi 294862457 1470 VIEKLQSEL 1478
Cdd:TIGR02168 962 KIEDDEEEA 970
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1123-1477 |
1.99e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1123 DLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEksvlWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQS 1202
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1203 EKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQ----------AAEREHEREEF 1272
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneeaanlrerLESLERRIAAT 836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1273 QQEIQRLEGQLRQAArprppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQ 1352
Cdd:TIGR02168 837 ERRLEDLEEQIEELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1353 RQMVQLQEELEKQKKSMEELKEKEIlKQENMGDLLLTTVSRSGLDEAGcpmlPQGSSSRGPEAQPDVTERALLQHENEVV 1432
Cdd:TIGR02168 908 SKRSELRRELEELREKLAQLELRLE-GLEVRIDNLQERLSEEYSLTLE----EAEALENKIEDDEEEARRRLKRLENKIK 982
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 294862457 1433 HRRN---SEIDELKSLIENLQENQRQlQKDKAEEIEQLHEVIEKLQSE 1477
Cdd:TIGR02168 983 ELGPvnlAAIEEYEELKERYDFLTAQ-KEDLTEAKETLEEAIEEIDRE 1029
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1056-1696 |
1.99e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1056 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 1135
Cdd:TIGR02168 288 KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1136 QQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNE---AKEREAALQEEVESLTRVQWESRKQ--------SEK 1204
Cdd:TIGR02168 368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerLEDRRERLQQEIEELLKKLEEAELKelqaeleeLEE 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1205 DRATLLSQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQR--LEGQ 1282
Cdd:TIGR02168 448 ELEELQEELERLEEALEELREELE---EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgILGV 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1283 LRQAARPRP----------PGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQ 1352
Cdd:TIGR02168 525 LSELISVDEgyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1353 RQMVQLQEELEKQKKSM-------EELKEK-EILKQENMGDLLLT----TVSRSG-------------------LDEAGC 1401
Cdd:TIGR02168 605 KDLVKFDPKLRKALSYLlggvlvvDDLDNAlELAKKLRPGYRIVTldgdLVRPGGvitggsaktnssilerrreIEELEE 684
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1402 PMLPQGSSSRGPEAQPDVTERALLQHENEV-------------VHRRNSEIDELKSLIENLQENQRQLQK---DKAEEIE 1465
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELeqlrkeleelsrqISALRKDLARLEAEVEQLEERIAQLSKeltELEAEIE 764
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1466 QLHEVIEKLQSELSLMGPKVHEVSDPQAG-------------SLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLA 1532
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEAEIEELEAQIEQlkeelkalrealdELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1533 NQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMA---SQIQEFAATLKAKEAIIEQRDLEIDAVNKWK 1609
Cdd:TIGR02168 845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrSELEELSEELRELESKRSELRRELEELREKL 924
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1610 VSHSLELEAILLALAHFRHALEQQTCATPDEPPELRQLRVQCARlshqlqvlyrpflKCRMQLDQHQPHVASIGCANPCA 1689
Cdd:TIGR02168 925 AQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE-------------EARRRLKRLENKIKELGPVNLAA 991
|
....*..
gi 294862457 1690 DDELEQE 1696
Cdd:TIGR02168 992 IEEYEEL 998
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
510-1186 |
2.12e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 2.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 510 KREAEERLASM------------------------------FLELREKAE----SEKLSIISRFEHRESSMRHLQDQQAA 555
Cdd:COG1196 174 KEEAERKLEATeenlerledilgelerqleplerqaekaerYRELKEELKeleaELLLLKLRELEAELEELEAELEELEA 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 556 QILDLERSLMEQQGHLRQLEQELTRDDLlpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAK 635
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 636 EQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKR- 714
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAa 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 715 HLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKEScHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHI 794
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 795 ENGKGPAADLQGAHQQDPAMALHNEGHLlveDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQD 874
Cdd:COG1196 480 AELLEELAEAAARLLLLLEAEADYEGFL---EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 875 QVAQVRDKvFLLNRELEecRAELEQLQQRRERENQEgttlicmlRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLK 954
Cdd:COG1196 557 EVAAAAIE-YLKAAKAG--RATFLPLDKIRARAALA--------AALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 955 SRISERAgllldheDAADTSDARLAAAALgdmwsdEGLLEIDRTLPEGAETSsvceisshvcesffispentldceqpiR 1034
Cdd:COG1196 626 TLVAARL-------EAALRRAVTLAGRLR------EVTLEGEGGSAGGSLTG---------------------------G 665
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1035 RVYQSLSTAVEGLLEMALDSSKQLEEARQLhrcvEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLL 1114
Cdd:COG1196 666 SRRELLAALLEAEAELEELAERLAEEELEL----EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 1115 EGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQ-------AARELLTLKEEKSVLWNQKETLTNEAKEREAALQE 1186
Cdd:COG1196 742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllAIEEYEELEERYDFLSEQREDLEEARETLEEAIEE 820
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
345-1163 |
2.04e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 345 SQLESMKTN-------REELNGSWDPVLAQASHLE-------ELEHLRSGFAQQQQQERAQHESELEHLrvyfEKKLKDA 410
Cdd:TIGR02168 179 RKLERTRENldrlediLNELERQLKSLERQAEKAErykelkaELRELELALLVLRLEELREELEELQEE----LKEAEEE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 411 EKTYQEDLTVFQQRLQEARedsLESTEISSSCVLPEETSGREGKEPPDpLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ 490
Cdd:TIGR02168 255 LEELTAELQELEEKLEELR---LEVSELEEEIEELQKELYALANEISR-LEQQKQILRERLANLERQLEELEAQLEELES 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 491 MKEEFQKKEAEWELSREELKREAEErLASMFLELREKAESEKLSIISRFEHRES------SMRHLQDQQAAQILDLERSL 564
Cdd:TIGR02168 331 KLDELAEELAELEEKLEELKEELES-LEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 565 MEQQGHLRQLEQELtrddllpcSQCGQEPAMAQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAfLRDA 644
Cdd:TIGR02168 410 ERLEDRRERLQQEI--------EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQA-LDAA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 645 QEKHNHelqllqqGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEIS---ALEKRHLSNLDE 721
Cdd:TIGR02168 481 ERELAQ-------LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 722 LESCYVADVQTIRdEHQQALELLRAELEEQLQKKESCHREMLTQelENLKRQHAEELQSVRDSLRMEMSAqhIENGKGPA 801
Cdd:TIGR02168 554 NLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKN--IEGFLGVAKDLVKFDPKLRKALSY--LLGGVLVV 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 802 ADLQGAHQQdpAMALHNEGHLLVEDGDAVLRSvdaeGLLhqAGPQELGDAHTVEMQKSQAELAkpQELQASQDQVAQVRD 881
Cdd:TIGR02168 629 DDLDNALEL--AKKLRPGYRIVTLDGDLVRPG----GVI--TGGSAKTNSSILERRREIEELE--EKIEELEEKIAELEK 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 882 KVFLLNRELEECRAELEQLQQRRERENQEgttlICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERA 961
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEELSRQ----ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 962 GLLLDHEDAADTSDARLAAAAlgdmwsdEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTL-DCEQPIRRVYQSL 1040
Cdd:TIGR02168 775 EELAEAEAEIEELEAQIEQLK-------EELKALREALDELRAELTLLNEEAANLRERLESLERRIaATERRLEDLEEQI 847
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1041 STAVEGLLEMAL----------DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTA 1110
Cdd:TIGR02168 848 EELSEDIESLAAeieeleelieELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1111 KGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 1163
Cdd:TIGR02168 928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1037-1598 |
2.43e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.07 E-value: 2.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1037 YQSLSTAVEGL-LEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRlalELHTAKGLLE 1115
Cdd:TIGR02168 215 YKELKAELRELeLALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE---EIEELQKELY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1116 GFKVEKVDLQEALGKKEESEQQLI-------LELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEV 1188
Cdd:TIGR02168 292 ALANEISRLEQQKQILRERLANLErqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1189 ESLT--RVQWESRK----QSEKDRATLLSQMRVLESELEDQLVQHrgcAQLAEEVATLKQQLAALDKH-LRSQRQFMDDQ 1261
Cdd:TIGR02168 372 SRLEelEEQLETLRskvaQLELQIASLNNEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAELKeLQAELEELEEE 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1262 AAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQcvQLDEEVELLqEKLREKLDGFNELVI-----KKDFAD----- 1331
Cdd:TIGR02168 449 LEELQEELERLEEALEELREELEEAEQALDAAERELA--QLQARLDSL-ERLQENLEGFSEGVKallknQSGLSGilgvl 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1332 QQLLIQEEEIKRLEETNASIQRQMVqLQEELEKQKKSMEELKEKEILKqenMGDLLLTTVSRSGLDEAGCPMLPQGSSSR 1411
Cdd:TIGR02168 526 SELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQNELGR---VTFLPLDSIKGTEIQGNDREILKNIEGFL 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1412 G---------PEAQPDVT-----------------ERALLQHEN-------EVVHR-----------------RNSEIDE 1441
Cdd:TIGR02168 602 GvakdlvkfdPKLRKALSyllggvlvvddldnaleLAKKLRPGYrivtldgDLVRPggvitggsaktnssileRRREIEE 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1442 LKSLIENLQENQRQLQK---DKAEEIEQLHEVIEKLQSELSLMGPKVHEvsdpqagsLHSELACLRGEGLGGQALRSELQ 1518
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKalaELRKELEELEEELEQLRKELEELSRQISA--------LRKDLARLEAEVEQLEERIAQLS 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1519 AAQAAKEVFGQLLANQAHGHSQALEALQQRLQDAEEVAARHLAELEhcvALREA--EVEAMASQIQEFAATLKAKEAIIE 1596
Cdd:TIGR02168 754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK---ALREAldELRAELTLLNEEAANLRERLESLE 830
|
..
gi 294862457 1597 QR 1598
Cdd:TIGR02168 831 RR 832
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
142-529 |
3.58e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.60 E-value: 3.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 142 LQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQ 221
Cdd:pfam02463 634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 222 DWESERELCLENLRQELSLKHQSEMEGLQSQF-QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA--IKKLQEDLQS 298
Cdd:pfam02463 714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIdEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREktEKLKVEEEKE 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 299 EHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLwSQLESMKTNREELNgswdpvlaqashlEELEHLR 378
Cdd:pfam02463 794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL-ALELKEEQKLEKLA-------------EEELERL 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 379 SGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:pfam02463 860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 459 PLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ-------MKEEFQKKEAEWELSREELKREAEERLASMFLELREKAE 529
Cdd:pfam02463 940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEElgkvnlmAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1084-1479 |
7.83e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 7.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1084 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLIL-ELEDLRKQLQQAARELLTLKEE 1162
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLkEKEALERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1163 KsvlwnqkETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEdqlvqhrgcaQLAEEVATLKQ 1242
Cdd:TIGR02169 253 L-------EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA----------SLERSIAEKER 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1243 QLaaldkhlrsqrQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRppgprdsqcVQLDEEVELLQEKLREKldgfne 1322
Cdd:TIGR02169 316 EL-----------EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR---------DKLTEEYAELKEELEDL------ 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1323 lvikkdfadqqlliqEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQEnmgdlllttvsrsgldeagcp 1402
Cdd:TIGR02169 370 ---------------RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE--------------------- 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1403 mLPQGSSSRGPEAQPDVTerALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQK------DKAEEIEQLHEVIEKLQS 1476
Cdd:TIGR02169 414 -ELQRLSEELADLNAAIA--GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKyeqelyDLKEEYDRVEKELSKLQR 490
|
...
gi 294862457 1477 ELS 1479
Cdd:TIGR02169 491 ELA 493
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2191-2504 |
9.37e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 9.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2191 EARGSQREHQLRRQVE-----LLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHackqentSLL 2265
Cdd:TIGR02168 208 QAEKAERYKELKAELRelelaLLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS-------ELE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2266 ESLDKVQQEVLRLRAVLDGKEKELKVVLEELESergkgqalQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQL 2345
Cdd:TIGR02168 281 EEIEELQKELYALANEISRLEQQKQILRERLAN--------LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2346 CVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALqherlltEQLSRNSQEACARQET 2425
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL-------ERLEDRRERLQQEIEE 425
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 2426 QVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKERELEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:TIGR02168 426 LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE--LEEAEQALDAAERELAQLQARLDSLERLQENLE 502
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1130-1553 |
1.95e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1130 KKEESEQQLILELEDLrKQLQQAARELltlkeEKsvlwnQKETLTNEAK--EREAALQEEVESLTRVQWESRKQSEKDRa 1207
Cdd:TIGR02168 173 RRKETERKLERTRENL-DRLEDILNEL-----ER-----QLKSLERQAEkaERYKELKAELRELELALLVLRLEELREE- 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1208 tlLSQMRVLESELEDQlvqhrgCAQLAEEVATLKQQLAALdkhlRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAA 1287
Cdd:TIGR02168 241 --LEELQEELKEAEEE------LEELTAELQELEEKLEEL----RLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1288 RprppgpRDSQCVQLDEEVELLQEKLREKLDgfnelvikkdfadqqllIQEEEIKRLEETNASIQRQMVQLQEELEKQKK 1367
Cdd:TIGR02168 309 E------RLANLERQLEELEAQLEELESKLD-----------------ELAEELAELEEKLEELKEELESLEAELEELEA 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1368 SMEELKEKEILKQENMGDLllttvsrsgldeagcpmlpqgsssrgpeaqpdvtERALLQHENEvVHRRNSEIDELKSLIE 1447
Cdd:TIGR02168 366 ELEELESRLEELEEQLETL----------------------------------RSKVAQLELQ-IASLNNEIERLEARLE 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1448 NLQENQRQLQKDKAEEIEQLHEVIEKLQSElslmgpkvhevsdpQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF 1527
Cdd:TIGR02168 411 RLEDRRERLQQEIEELLKKLEEAELKELQA--------------ELEELEEELEELQEELERLEEALEELREELEEAEQA 476
|
410 420
....*....|....*....|....*.
gi 294862457 1528 GQLLANQAHGHSQALEALQQRLQDAE 1553
Cdd:TIGR02168 477 LDAAERELAQLQARLDSLERLQENLE 502
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1309-1601 |
2.29e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 2.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1309 LQEKLREKLdgFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMgDLLL 1388
Cdd:COG1196 218 LKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1389 TTVSRSGLDEAgcpmlpqgsssrgpeaqpdvTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLH 1468
Cdd:COG1196 295 AELARLEQDIA--------------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1469 EVIEKLQSelslmgpkvhevsdpQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLANQAHGHSQALEALQQR 1548
Cdd:COG1196 355 EAEAELAE---------------AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1549 LQDAEEVAARHLAELEHCVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLE 1601
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
156-430 |
2.41e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 2.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 156 MLNGRRAQELALLQSRQQcELELLREQhaREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE---SERELCLE 232
Cdd:TIGR02168 660 VITGGSAKTNSSILERRR-EIEELEEK--IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqiSALRKDLA 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 233 NLRQ--ELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEA---QHQAAIKKLQEDLQSEHCQY--LQ 305
Cdd:TIGR02168 737 RLEAevEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAELtlLN 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 306 DLEQKFREKEKAKELELETLQASYEDLKAQS---QEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFA 382
Cdd:TIGR02168 817 EEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 294862457 383 QQQQQERAQHESELEHLRVYFEkKLKDAEKTYQEDLTVFQQRLQEARE 430
Cdd:TIGR02168 897 EELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQE 943
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1074-1282 |
1.27e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.54 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1074 HRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKvdLQEALGKKEESEQQLILELEDLRKQLQQAA 1153
Cdd:COG4913 238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1154 RELLTLKEEKSVLwnqKETLTNEAKEREAALQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESEL---EDQLVQHRgc 1230
Cdd:COG4913 316 ARLDALREELDEL---EAQIRGNGGDRLEQLEREIERLER----ELEERERRRARLEALLAALGLPLpasAEEFAALR-- 386
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 294862457 1231 AQLAEEVATLKQQLAALDKHLRSQRqfmdDQAAEREHEREEFQQEIQRLEGQ 1282
Cdd:COG4913 387 AEAAALLEALEEELEALEEALAEAE----AALRDLRRELRELEAEIASLERR 434
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1048-1371 |
1.32e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1048 LEMALDSSKQLEEARQLHRCVEREFRHR----NEEMAQAmQKQQELLERLREesAAKDRLALELHTAKGLLEGFKVEKVD 1123
Cdd:TIGR02169 172 KEKALEELEEVEENIERLDLIIDEKRQQlerlRREREKA-ERYQALLKEKRE--YEGYELLKEKEALERQKEAIERQLAS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1124 LQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK-ETLTNEAKEREAALQEEVESLTRVQwESRKQS 1202
Cdd:TIGR02169 249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAE-ERLAKL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1203 EKDRATLLSQMRVLESELEDQLVQHRGC----AQLAEEVATLKQQLAALDKHLRSQRQFMDD----------QAAEREHE 1268
Cdd:TIGR02169 328 EAEIDKLLAEIEELEREIEEERKRRDKLteeyAELKEELEDLRAELEEVDKEFAETRDELKDyrekleklkrEINELKRE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1269 REEFQQEIQRLEGQLRQAaRPRPPGPRDSQcVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETN 1348
Cdd:TIGR02169 408 LDRLQEELQRLSEELADL-NAAIAGIEAKI-NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485
|
330 340
....*....|....*....|...
gi 294862457 1349 ASIQRQMvqlqEELEKQKKSMEE 1371
Cdd:TIGR02169 486 SKLQREL----AEAEAQARASEE 504
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2183-2422 |
1.41e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2183 LCAALTSTEARGSQREHQLRRQVELLAYKVEQEkcianELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENT 2262
Cdd:COG4942 5 LLLALLLALAAAAQADAAAEAEAELEQLQQEIA-----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2263 SLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKGQAL---QAQQEEQQLRYLQREGQSSRALEELKLSLEKQL 2339
Cdd:COG4942 80 ALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllSPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2340 AQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEA 2419
Cdd:COG4942 160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
...
gi 294862457 2420 CAR 2422
Cdd:COG4942 240 AER 242
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2160-2419 |
1.47e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2160 AEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQRE------HQLRRQVELLAYKVEQEKCIANELQKTLSKEQETA 2233
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEqlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2234 SDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKvvleELESERGKgqalqaqQEEQ 2313
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT----LLNEEAAN-------LRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2314 QLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQI---EASRCEALLAQEKGQLSELQKSLEA 2390
Cdd:TIGR02168 826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEEALALLRSELEELSEELRE 905
|
250 260
....*....|....*....|....*....
gi 294862457 2391 ERSRSLELSEALQHERLLTEQLSRNSQEA 2419
Cdd:TIGR02168 906 LESKRSELRRELEELREKLAQLELRLEGL 934
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
485-1370 |
2.28e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.44 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 485 EEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSL 564
Cdd:pfam02463 194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKE 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 565 MEQQghLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKedcaLQLLMAQNRFLEERKEimekfaKEQDAFLRDA 644
Cdd:pfam02463 274 NKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK----LKESEKEKKKAEKELK------KEKEEIEELE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 645 QEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELES 724
Cdd:pfam02463 342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 725 CYVADVQTIRDEHQQALELLRAELEEQLQKKEschremLTQELENLKRQHAEELQSVRdslrmemsAQHIENGKGPAADL 804
Cdd:pfam02463 422 KEEKKEELEILEEEEESIELKQGKLTEEKEEL------EKQELKLLKDELELKKSEDL--------LKETQLVKLQEQLE 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 805 QGAHQQDPAMALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVemqksqAELAKPQELQASQDQVAQVRDKVF 884
Cdd:pfam02463 488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA------VENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 885 llnrELEECRAELEQLQQRRERENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLL 964
Cdd:pfam02463 562 ----ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 965 LDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAV 1044
Cdd:pfam02463 638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1045 EGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALEL-HTAKGLLEGFKVEKVD 1123
Cdd:pfam02463 718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEReKTEKLKVEEEKEEKLK 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1124 LQEALGKKEESEQQLILEledlrkQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqSE 1203
Cdd:pfam02463 798 AQEEELRALEEELKEEAE------LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL----------EE 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1204 KDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIqRLEGQL 1283
Cdd:pfam02463 862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE-EEPEEL 940
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1284 RQAARPRPPGPRDSqcvQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1363
Cdd:pfam02463 941 LLEEADEKEKEENN---KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
|
....*..
gi 294862457 1364 KQKKSME 1370
Cdd:pfam02463 1018 RLKEFLE 1024
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1055-1462 |
3.69e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.13 E-value: 3.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1055 SKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALElhTAKGLLEGFKVEKVDLQEALGKKEES 1134
Cdd:TIGR00606 446 KEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTE--TLKKEVKSLQNEKADLDRKLRKLDQE 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1135 EQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLT-----------------------NEAKEREAALQEEVESL 1191
Cdd:TIGR00606 524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTsllgyfpnkkqledwlhskskeiNQTRDRLAKLNKELASL 603
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1192 TRVQWESRKQSEKDRATLLSqmrvleseLEDQLVQHRGC-------AQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAE 1264
Cdd:TIGR00606 604 EQNKNHINNELESKEEQLSS--------YEDKLFDVCGSqdeesdlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDE 675
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1265 RE------HEREEFQQEIQRLEGQLRQAARPRPpgprdsqcvqldEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE 1338
Cdd:TIGR00606 676 NQsccpvcQRVFQTEAELQEFISDLQSKLRLAP------------DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1339 EEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPD 1418
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT 823
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 294862457 1419 VTE-RALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAE 1462
Cdd:TIGR00606 824 VQQvNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
117-577 |
4.25e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 4.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 117 SLELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQeLALLQSRQQCELELLREQHAREKEEMALRSGQ 196
Cdd:pfam12128 252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 197 EAAELKEKLrsemEKNAQTIETLKQdWESErelcLENLRQELSL---KHQSEMEGLQSQFQKELSEQKVELEKIFQAKHE 273
Cdd:pfam12128 331 HGAFLDADI----ETAAADQEQLPS-WQSE----LENLEERLKAltgKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 274 AEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDL-EQKFREKEKAKELELETLQASY-EDLK---AQSQEEIRLLWSQLE 348
Cdd:pfam12128 402 IREARDRQLAVAEDDLQALESELREQLEAGKLEFnEEEYRLKSRLGELKLRLNQATAtPELLlqlENFDERIERAREEQE 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 349 SMKTNREELNGSwdpvLAQASHLEELEHLRSGFAQQQQQERAQHESELEH--------LRVYFEK----------KLKDA 410
Cdd:pfam12128 482 AANAEVERLQSE----LRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtLLHFLRKeapdweqsigKVISP 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 411 EKTYQEDLTVFQQRLQEAREDS-------LESTEISSSCVLPEETSGREGKeppdpldlqlgqpkvQESLVEDCQVKLSK 483
Cdd:pfam12128 558 ELLHRTDLDPEVWDGSVGGELNlygvkldLKRIDVPEWAASEEELRERLDK---------------AEEALQSAREKQAA 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 484 AEEKIQQMKEEFQKKEAEWELSREELKrEAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERS 563
Cdd:pfam12128 623 AEEQLVQANGELEKASREETFARTALK-NARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAW 701
|
490
....*....|....
gi 294862457 564 LMEQQGHLRQLEQE 577
Cdd:pfam12128 702 LEEQKEQKREARTE 715
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
145-519 |
4.63e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 4.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 145 EKETALTELREMlnGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE 224
Cdd:TIGR02169 171 KKEKALEELEEV--EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 225 SEREL---------------CLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAI 289
Cdd:TIGR02169 249 LEEELeklteeiselekrleEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 290 KKLQEdLQSEHCQYLQDLEQKFREKEKAKElELETLQASYEDLKAQSQE---EIRLLWSQLESMKTNREELNGSWDPVLA 366
Cdd:TIGR02169 329 AEIDK-LLAEIEELEREIEEERKRRDKLTE-EYAELKEELEDLRAELEEvdkEFAETRDELKDYREKLEKLKREINELKR 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 367 QASHLEELEHLRSGfaqqqqqERAQHESELEHLRvyfekklkdaektyqEDLTVFQQRLQEAREdslestEIssscvlpe 446
Cdd:TIGR02169 407 ELDRLQEELQRLSE-------ELADLNAAIAGIE---------------AKINELEEEKEDKAL------EI-------- 450
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 447 etsgregkeppdpldlqlgqpKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEERLAS 519
Cdd:TIGR02169 451 ---------------------KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS 502
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2175-2494 |
8.57e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.68 E-value: 8.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2175 QNQEKLQQLCAALTSTEARGSQREHQLRRQVELlayKVEQEKCIANELQKT--LSKEQETASDVRKRLVVEQNAVQDLKS 2252
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEA---KKAEEKKKADELKKAeeLKKAEEKKKAEEAKKAEEDKNMALRKA 1583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2253 ELhaCKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESErgkgqalqAQQEEQQLRYLQREGQSSRALEELK 2332
Cdd:PTZ00121 1584 EE--AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA--------EEEKKKVEQLKKKEAEEKKKAEELK 1653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2333 LSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALL--AQEKGQLSELQKSLEAERSRSLELSEALQHERLLTE 2410
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2411 QLSRNSQEacarqetqvqhallRKLKAEKTRALELEAmlEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDE 2490
Cdd:PTZ00121 1734 EAKKEAEE--------------DKKKAEEAKKDEEEK--KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
|
....
gi 294862457 2491 HKIE 2494
Cdd:PTZ00121 1798 KKIK 1801
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
2197-2504 |
9.87e-06 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 51.29 E-value: 9.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2197 REHQLRRQVELLAYKVEQEKCIaNELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVL 2276
Cdd:pfam07111 312 REKVFALMVQLKAQDLEHRDSV-KQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARR 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2277 RLRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLR---------YLQREGQSSRALEELKLSLEKQLAQ------ 2341
Cdd:pfam07111 391 RQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARipslsnrlsYAVRKVHTIKGLMARKVALAQLRQEscpppp 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2342 -----NNQLCVALKHERAAKDNLQKELQI-------EASRCEALLAQEKGQLSELQKSLEAERSRS--------LELSEA 2401
Cdd:pfam07111 471 pappvDADLSLELEQLREERNRLDAELQLsahliqqEVGRAREQGEAERQQLSEVAQQLEQELQRAqeslasvgQQLEVA 550
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2402 LQHERLLTEQLSRNSQEACARQETQVQhALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERE 2481
Cdd:pfam07111 551 RQGQQESTEEAASLRQELTQQQEIYGQ-ALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERN 629
|
330 340
....*....|....*....|...
gi 294862457 2482 LEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:pfam07111 630 QELRRLQDEARKEEGQRLARRVQ 652
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
119-357 |
1.20e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.89 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 119 ELEALRLSLNNMHTAQLELTQANLQKEKETALTEL---REMLNGRRAQelallqsrqqcELELLREQHAREKEEMalRSG 195
Cdd:pfam17380 349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLqmeRQQKNERVRQ-----------ELEAARKVKILEEERQ--RKI 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 196 QEAAELKEKLRSEMEkNAQTIETLKQDWESERElcLENLRQElSLKHQSEMEGLQSQfQKELSEQKVELEKIFQAKHEAE 275
Cdd:pfam17380 416 QQQKVEMEQIRAEQE-EARQREVRRLEEERARE--MERVRLE-EQERQQQVERLRQQ-EEERKRKKLELEKEKRDRKRAE 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 276 -----VSLKNLEAQHQAAI------KKLQEDLQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEirllw 344
Cdd:pfam17380 491 eqrrkILEKELEERKQAMIeeerkrKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEER----- 565
|
250
....*....|...
gi 294862457 345 SQLESMKTNREEL 357
Cdd:pfam17380 566 SRLEAMEREREMM 578
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2191-2509 |
1.33e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2191 EARGSQREHQLRRQVELLAYKVEQEKCIANELQKTlSKEQETASDVRKrlVVEQNAVQDLKSELHACKQENTSLLESLDK 2270
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA-AEAKKKADEAKK--AEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2271 VQQevlrLRavldgKEKELKVVLEELESERGKGQALQAQQEEQQLRYLqREGQSSRALEELKLSLEKQLAQNNQLCVA-- 2348
Cdd:PTZ00121 1548 ADE----LK-----KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA-KKAEEARIEEVMKLYEEEKKMKAEEAKKAee 1617
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2349 ----------LKHERAAKDNLQKELQIEASRCEALLAQE---KGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRN 2415
Cdd:PTZ00121 1618 akikaeelkkAEEEKKKVEQLKKKEAEEKKKAEELKKAEeenKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2416 SQEACARQEtqvqhalLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQR-QRDEHKIE 2494
Cdd:PTZ00121 1698 AEEAKKAEE-------LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHlKKEEEKKA 1770
|
330
....*....|....*
gi 294862457 2495 QLQRLVRELRWKEEV 2509
Cdd:PTZ00121 1771 EEIRKEKEAVIEEEL 1785
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
134-501 |
2.06e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 134 QLELTQANLQKeKETALTELREMLNGRRAQ-ELAllqsrqqcelELLREQHAREKE---EMALRSGQEAAELKEKLRSEM 209
Cdd:TIGR02168 180 KLERTRENLDR-LEDILNELERQLKSLERQaEKA----------ERYKELKAELRElelALLVLRLEELREELEELQEEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 210 EKNAQTIETLkQDWESERELCLENLRQElslkhQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAI 289
Cdd:TIGR02168 249 KEAEEELEEL-TAELQELEEKLEELRLE-----VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 290 KKLQEDLQSEHCQylqdleqkfREKEKAKELELETLQASYEDLKAQSQEEIRllwsQLESMKTNREELNgswdpvlaqas 369
Cdd:TIGR02168 323 AQLEELESKLDEL---------AEELAELEEKLEELKEELESLEAELEELEA----ELEELESRLEELE----------- 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 370 hlEELEHLRSGFAqQQQQERAQHESELEHLrvyfEKKLKDAEKTYQEdltvfQQRLQEAREDSLESTEIssscvlpEETS 449
Cdd:TIGR02168 379 --EQLETLRSKVA-QLELQIASLNNEIERL----EARLERLEDRRER-----LQQEIEELLKKLEEAEL-------KELQ 439
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 294862457 450 GREGKEPPDPLDLQLGQPKVQESLvEDCQVKLSKAEEKIQQMKEEFQKKEAE 501
Cdd:TIGR02168 440 AELEELEEELEELQEELERLEEAL-EELREELEEAEQALDAAERELAQLQAR 490
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1053-1376 |
2.39e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1053 DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQ-KQQELLERLREESAAKDRLALELHTAKgllEGFKVEKVDLQEALGKK 1131
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLY 1601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1132 EESEQqliLELEDLRKQLQQ--AARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSE-KDRAT 1208
Cdd:PTZ00121 1602 EEEKK---MKAEEAKKAEEAkiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdKKKAE 1678
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1209 LLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQ---RQFMDDQAAEREHEREEFQQEIQRLEGQLRQ 1285
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1286 AARPRPPGPRDSQCVQLDEEVeLLQEKLREKLDGFNELVIK--KDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1363
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEA-VIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837
|
330
....*....|...
gi 294862457 1364 KQKKSMEELKEKE 1376
Cdd:PTZ00121 1838 SKNMQLEEADAFE 1850
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2083-2509 |
2.63e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2083 EKESLETHLTWSEELLRAIQEVFAREQEKAELQprpygsnlGDYNSLVQRLEKVIQEQGDPQKVQDHLcLSDRSSLLAEI 2162
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAE--------AELAEAEEALLEAEAELAEAEEELEEL-AEELLEALRAA 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2163 QALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVV 2242
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2243 EQnAVQDLKSELHACKQENTSLLE---------------SLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGK-GQAL 2306
Cdd:COG1196 476 EA-ALAELLEELAEAAARLLLLLEaeadyegflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQnIVVE 554
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2307 QAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALL-------AQEKG 2379
Cdd:COG1196 555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgrtlvaARLEA 634
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2380 QLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ-----ETQVQHALLRKLKAEKTRALELEAMLEKVQK 2454
Cdd:COG1196 635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEaeleeLAERLAEEELELEEALLAEEEEERELAEAEE 714
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 294862457 2455 QAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEHKIEQLQRLVRELRWKEEV 2509
Cdd:COG1196 715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
144-542 |
2.94e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 144 KEKETALTELREMLNG--RRAQELALLQSR-QQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLK 220
Cdd:PRK03918 210 NEISSELPELREELEKleKEVKELEELKEEiEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 221 QDWESERELC---------LENLRQELSlKHQSEMEGLQSQFqKELSEQKVELEKIFQAKHEAEVSLKNLEAQHqaaikK 291
Cdd:PRK03918 290 EKAEEYIKLSefyeeyldeLREIEKRLS-RLEEEINGIEERI-KELEEKEERLEELKKKLKELEKRLEELEERH-----E 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 292 LQEDLqsehcqyLQDLEQKFREKEKAKELELETLQASYEDL---KAQSQEEIRLLWSQLESMKTNREELNgswdpvlaqa 368
Cdd:PRK03918 363 LYEEA-------KAKKEELERLKKRLTGLTPEKLEKELEELekaKEEIEEEISKITARIGELKKEIKELK---------- 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 369 shlEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREdsLESTEISSSCVLPEET 448
Cdd:PRK03918 426 ---KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKE 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 449 SGREGKEppdpldlqlgqpkVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAE--ERLASMFLELRE 526
Cdd:PRK03918 501 LAEQLKE-------------LEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEElkKKLAELEKKLDE 567
|
410
....*....|....*.
gi 294862457 527 kAESEKLSIISRFEHR 542
Cdd:PRK03918 568 -LEEELAELLKELEEL 582
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1142-1361 |
3.77e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 3.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1142 LEDLRKQLQQAARELLTLKEEKSVLWNQKETLTneakEREAALQEevesLTRVQWEsrkqsEKDRATLLSQMRVLESELE 1221
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQ----ERREALQR----LAEYSWD-----EIDVASAEREIAELEAELE 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1222 DQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddqaaerehEREEFQQEIQRLEGQLRQAARprppgprdsqcvQ 1301
Cdd:COG4913 679 RLDASSDDLAALEEQLEELEAELEELEEELDELKG-----------EIGRLEKELEQAEEELDELQD------------R 735
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1302 LDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEE 1361
Cdd:COG4913 736 LEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
116-798 |
3.98e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.58 E-value: 3.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 116 HSLELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSG 195
Cdd:pfam02463 193 EELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 196 QEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKElsEQKVELEKIFQAKHEAE 275
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE--KEEIEELEKELKELEIK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 276 VSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDLEQKFREKEKAKELELEtlqasYEDLKAQSQEEIRLLWSQLESMKTNRE 355
Cdd:pfam02463 351 REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-----LKSEEEKEAQLLLELARQLEDLLKEEK 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 356 ElngswdpvlAQASHLEELEHLRsGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLES 435
Cdd:pfam02463 426 K---------EELEILEEEEESI-ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 436 TEISSSCVLPEETSGREGKEPPDPLDLQLG---------QPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSR 506
Cdd:pfam02463 496 EERSQKESKARSGLKVLLALIKDGVGGRIIsahgrlgdlGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 507 EELKREAEERLASMFLELREKAESEKLSIISRFEHRE-SSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLLP 585
Cdd:pfam02463 576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 586 CSQCGQEPAMAQ--EEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQL 663
Cdd:pfam02463 656 EGLAEKSEVKASlsELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 664 LALRmELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALEL 743
Cdd:pfam02463 736 EELK-LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 294862457 744 LRAELEEQLQKKESCHREMLTQELENLK--RQHAEELQSVRDSLRMEMSAQHIENGK 798
Cdd:pfam02463 815 ELLEEEQLLIEQEEKIKEEELEELALELkeEQKLEKLAEEELERLEEEITKEELLQE 871
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
203-532 |
4.94e-05 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 48.86 E-value: 4.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 203 EKLRSEMEKNAQT--------IETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKvelekifqaKHEA 274
Cdd:NF033838 72 SEIQKSLDKRKHTqnvalnkkLSDIKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPG---------KKVA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 275 EVSLKNLEAQHQAAIKKlQEDLQSEHCQYLQDLEQKFREKE-KAKELELETLQAsyEDLKAQSQEEIRLLWSQLESMKtn 353
Cdd:NF033838 143 EATKKVEEAEKKAKDQK-EEDRRNYPTNTYKTLELEIAESDvEVKKAELELVKE--EAKEPRDEEKIKQAKAKVESKK-- 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 354 reelngswdpvlAQASHLEELEHLRsgfaqqqqqERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR--LQE-ARE 430
Cdd:NF033838 218 ------------AEATRLEKIKTDR---------EKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRgvLGEpATP 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 431 DSLESTEISSSCVLPEETsgregkePPDPlDLQLGQpKVQESlvedcQVKLSKAEEKIQQMKEEFQK------------- 497
Cdd:NF033838 277 DKKENDAKSSDSSVGEET-------LPSP-SLKPEK-KVAEA-----EKKVEEAKKKAKDQKEEDRRnyptntyktlele 342
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 294862457 498 --------KEAEWELSREELKR-EAEERLAsmflELREKAESEK 532
Cdd:NF033838 343 iaesdvkvKEAELELVKEEAKEpRNEEKIK----QAKAKVESKK 382
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1034-1476 |
7.01e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 48.50 E-value: 7.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1034 RRVYQSLSTAVEGLL-EMALDS--SKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTA 1110
Cdd:PRK02224 285 RERLEELEEERDDLLaEAGLDDadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1111 KGLLEGfkvEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVES 1190
Cdd:PRK02224 365 AAELES---ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARER 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1191 LTRVQ--WESRK-----QSEKD--RATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQ 1261
Cdd:PRK02224 442 VEEAEalLEAGKcpecgQPVEGspHVETIEEDRERVEELEAEL------EDLEEEVEEVEERLERAEDLVEAEDRIERLE 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1262 AAEREHEREEFQQEiQRLEGQLRQAARPRppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEI 1341
Cdd:PRK02224 516 ERREDLEELIAERR-ETIEEKRERAEELR------ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1342 KRLeETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDL------LLTTVSRSGLDEAgcpmlpQGSSSRGPEA 1415
Cdd:PRK02224 589 ESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKrerkreLEAEFDEARIEEA------REDKERAEEY 661
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1416 QPDVTE--RALLQHENEVVHRRNSEIDELKSLiENLQENQRQLQkDKAEEIEQLHEVIEKLQS 1476
Cdd:PRK02224 662 LEQVEEklDELREERDDLQAEIGAVENELEEL-EELRERREALE-NRVEALEALYDEAEELES 722
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2262-2508 |
7.30e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.51 E-value: 7.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2262 TSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRaLEELKLSLEKQLAQ 2341
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR-LEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2342 NNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSrslELSEALQHERLLTEQL-SRNSQEAC 2420
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA---ELEELESRLEELEEQLeTLRSKVAQ 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2421 ARQETQVQHALLRKLKAEKTRaleLEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEHKIEQLQRLV 2500
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLER---LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467
|
....*...
gi 294862457 2501 RELRWKEE 2508
Cdd:TIGR02168 468 EELEEAEQ 475
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
242-914 |
8.48e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 8.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 242 HQSEMEGLQ---SQFQKELSEQKVELEKIFQAKHEAEVSLKNL------EAQHQAAIKKLQEDLQSEHCQYLQDLeQKFR 312
Cdd:PTZ00121 1065 HVGQDEGLKpsyKDFDFDAKEDNRADEATEEAFGKAEEAKKTEtgkaeeARKAEEAKKKAEDARKAEEARKAEDA-RKAE 1143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 313 EKEKAKELELETLQASYEDlkAQSQEEIRLLWSQLESMKTNREElngswdpVLAQASHLEELEHLRsgfaQQQQQERAQH 392
Cdd:PTZ00121 1144 EARKAEDAKRVEIARKAED--ARKAEEARKAEDAKKAEAARKAE-------EVRKAEELRKAEDAR----KAEAARKAEE 1210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 393 ESELEHLRVYFEKKLKDAEKtyqedltvfqqRLQEAREDSLEST---EISSSCVLPEETSGREGKEPPDPLDLQLGQPKV 469
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKAEAVK-----------KAEEAKKDAEEAKkaeEERNNEEIRKFEEARMAHFARRQAAIKAEEARK 1279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 470 QESLVEDCQVK----LSKAEEKiqqMKEEFQKKEAEWELSREELKREAEERLASMfLELREKAESEKLSIISRFEHRESS 545
Cdd:PTZ00121 1280 ADELKKAEEKKkadeAKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEEAKKAAEAAKAEAEAA 1355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 546 MRHLQ-DQQAAQILDLERSLMEQQGH-LRQLEQELTRDDLLPcSQCGQEPAMAQEEKNGALLREKEDcALQLLMAQNRFL 623
Cdd:PTZ00121 1356 ADEAEaAEEKAEAAEKKKEEAKKKADaAKKKAEEKKKADEAK-KKAEEDKKKADELKKAAAAKKKAD-EAKKKAEEKKKA 1433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 624 EERKEIMEKfAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASsESRRQALLETHVAELQVK 703
Cdd:PTZ00121 1434 DEAKKKAEE-AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE-EAKKKADEAKKAAEAKKK 1511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 704 HNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKESCHREMLTQELENLKRQHAEELQSVRD 783
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 784 SLRMEMSAQHIENGKGPAADLQGAHQ-QDPAMALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAE 862
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 294862457 863 LAKPQELQASQDQVAQvRDKVFLLNRELEECRaELEQLQQRRERENQEGTTL 914
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDE-KKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEEL 1721
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2185-2508 |
8.48e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 8.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2185 AALTSTEARGSQREHQLRRQVELLAYKVEQEKcIANELQKTlSKEQETASDVRKRlvveqnAVQDLKSELHACKQENTSL 2264
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAK-KADEAKKK-AEEAKKAEEAKKK------AEEAKKADEAKKKAEEAKK 1484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2265 LESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQ 2344
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK 1564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2345 lcvalKHERAAKDNLQKELQIEasRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLsRNSQEACARQE 2424
Cdd:PTZ00121 1565 -----KAEEAKKAEEDKNMALR--KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-KKAEEEKKKVE 1636
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2425 TQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKERELEiQRQRDEHKIEQLQRLVRELR 2504
Cdd:PTZ00121 1637 QLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK-KEAEEAKKAEELKKKEAEEK 1715
|
....
gi 294862457 2505 WKEE 2508
Cdd:PTZ00121 1716 KKAE 1719
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1069-1374 |
1.00e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.30 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1069 EREFRHRNEEMAQAMQKQQELLERLREEsaakdrlaleLHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQ 1148
Cdd:pfam12128 599 EEELRERLDKAEEALQSAREKQAAAEEQ----------LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDK 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1149 LQQAarelltLKEEKSVLWNQKETLTNEAKEREAALQEEVEsltrvqwESRKQSEKDRATLLSQMRVLESELEDQLvqhr 1228
Cdd:pfam12128 669 KNKA------LAERKDSANERLNSLEAQLKQLDKKHQAWLE-------EQKEQKREARTEKQAYWQVVEGALDAQL---- 731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1229 gcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPR--DSQCVQLDEEV 1306
Cdd:pfam12128 732 --ALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRR 809
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 294862457 1307 ELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKR----LEETNASIQRQMVQLQEELEKQKKSMEELKE 1374
Cdd:pfam12128 810 PRLATQLSNIERAISEL-------QQQLARLIADTKLrrakLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
203-319 |
1.19e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 47.90 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 203 EKLRSEMEKNAQTIETLKQDweserelcLENLRQELslkhQSEMEGLQSQFQKELSEQKVEL-EKIFQAKHEAEVSLKNL 281
Cdd:PRK00409 526 EELERELEQKAEEAEALLKE--------AEKLKEEL----EEKKEKLQEEEDKLLEEAEKEAqQAIKEAKKEADEIIKEL 593
|
90 100 110
....*....|....*....|....*....|....*....
gi 294862457 282 EAQHQAAIKKLQE-DLQSEHCQYLQDLEQKFREKEKAKE 319
Cdd:PRK00409 594 RQLQKGGYASVKAhELIEARKRLNKANEKKEKKKKKQKE 632
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1070-1381 |
1.21e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1070 REFRHRNEEMAQAMQKQQELLERLREesaakdrLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQL 1149
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIID-------LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1150 QQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDqlvqhrg 1229
Cdd:pfam02463 239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD------- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1230 caqLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEG--QLRQAARPRPPGPRDSQC---VQLDE 1304
Cdd:pfam02463 312 ---DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEEleKLQEKLEQLEEELLAKKKlesERLSS 388
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 294862457 1305 EVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE 1381
Cdd:pfam02463 389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
851-1451 |
1.27e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 851 AHTVEMQKSQAELAKPQELQASQDQVAQVRdKVFLLNRELEECRAELEQLQQRRERenqegttlicmLRADLELAQGEgk 930
Cdd:COG4913 259 ELAERYAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELER-----------LEARLDALREE-- 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 931 aLRDALRRLLDLFGDTLKAavtLKSRISERAGLLLDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAEtssvce 1010
Cdd:COG4913 325 -LDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE------ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1011 isshvcesffispentldceqpirrvyqslstavegllemaldsskqlEEARQLHRCVEREFRHRNEEmAQAMQKQQELL 1090
Cdd:COG4913 395 ------------------------------------------------ALEEELEALEEALAEAEAAL-RDLRRELRELE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1091 ERLREESAAKDRLALELHTAKGLLEgfkvekvdlqEALGKKEeseqqlilelEDLRkqlqqAARELLTLKEEKS------ 1164
Cdd:COG4913 426 AEIASLERRKSNIPARLLALRDALA----------EALGLDE----------AELP-----FVGELIEVRPEEErwrgai 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1165 --VLWNQKETLTNEAkEREAALQEEVESL---TRVQWE-------SRKQSEKDRATLLSQMRVLESELED---QLVQHRG 1229
Cdd:COG4913 481 erVLGGFALTLLVPP-EHYAAALRWVNRLhlrGRLVYErvrtglpDPERPRLDPDSLAGKLDFKPHPFRAwleAELGRRF 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1230 CAQLAEEVATLKQQ-----LAALDKHLRSQRQfMDDQAAER---------EHEREEFQQEIQRLEGQLRQAarprppgpr 1295
Cdd:COG4913 560 DYVCVDSPEELRRHpraitRAGQVKGNGTRHE-KDDRRRIRsryvlgfdnRAKLAALEAELAELEEELAEA--------- 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1296 DSQCVQLDEEVELLQEKLR--EKLDGFNELVIKKDFADQQLLIQEEEIKRLEETN---ASIQRQMVQLQEELEKQKKSME 1370
Cdd:COG4913 630 EERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELD 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1371 ELKEKEILKQENMGDLL-LTTVSRSGLDEAGcpmlPQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKSLIENL 1449
Cdd:COG4913 710 ELKGEIGRLEKELEQAEeELDELQDRLEAAE----DLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785
|
..
gi 294862457 1450 QE 1451
Cdd:COG4913 786 EE 787
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1141-1375 |
1.43e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 1.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1141 ELEDLRKQLQQAARELLTLKEEKSVLwnqkeTLTNEAKEREAALQEEVESLTRVQweSRKQSEKDRATLLSQMRVLESEL 1220
Cdd:COG3206 183 QLPELRKELEEAEAALEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEAR--AELAEAEARLAALRAQLGSGPDA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1221 EDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMddqaaereherEEFQQEIQRLEGQLRQAARprppgprdSQCV 1300
Cdd:COG3206 256 LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQEAQ--------RILA 316
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294862457 1301 QLDEEVELLQEKLREkldgfnelvikkdfADQQLLIQEEEIKRLeetnASIQRQMVQLQEELEKQKKSMEELKEK 1375
Cdd:COG3206 317 SLEAELEALQAREAS--------------LQAQLAQLEARLAEL----PELEAELRRLEREVEVARELYESLLQR 373
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
136-409 |
1.45e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 136 ELTQANLQKEKEtaltELREMLNGRRAQELALLQSRQQCELELLREQHAREKEE--MALRSGQEAAELKEKLRSEMEKNA 213
Cdd:PTZ00121 1526 EAKKAEEAKKAD----EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLY 1601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 214 QTIETLKQDWESERElclENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQ 293
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAE---EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 294 EDLQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEE 373
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 294862457 374 LEHLRSGFAQQQQQERAQHES--------ELEHLRVYFEKKLKD 409
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEAvieeeldeEDEKRRMEVDKKIKD 1802
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2131-2504 |
1.75e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.27 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2131 QRLEKVIQEQGDPQKVQDHLCLSDRSSLLAEIQALRAqlrMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAY 2210
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKA---LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2211 KVEQEKcianeLQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELK 2290
Cdd:pfam02463 250 QEEIES-----SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2291 VVLEELESERGKGQalqaqqeeqqlrylqregQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRC 2370
Cdd:pfam02463 325 KAEKELKKEKEEIE------------------ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2371 EALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELEAMLE 2450
Cdd:pfam02463 387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 294862457 2451 KVQKQAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:pfam02463 467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
119-722 |
1.92e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 119 ELEALRLSLNNMHTAQLELT---------QANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEE 189
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQkelyalaneISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 190 MALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSL-KHQSEMEGLQSQFQKELSEQKVELEKIF 268
Cdd:TIGR02168 348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLEDRRERLQQEIEELL 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 269 QAKHEAEVSLKNLE-AQHQAAIKKLQEDLQSEHCQY--LQDLEQKFREKEKAKELELETLQASYEDLKAQsQEEIRLLWS 345
Cdd:TIGR02168 428 KKLEEAELKELQAElEELEEELEELQEELERLEEALeeLREELEEAEQALDAAERELAQLQARLDSLERL-QENLEGFSE 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 346 QLESMKTNREELNGSWDPVLAQ---------------------------------ASHLEELEHLRSGFAQQQQQERAQH 392
Cdd:TIGR02168 507 GVKALLKNQSGLSGILGVLSELisvdegyeaaieaalggrlqavvvenlnaakkaIAFLKQNELGRVTFLPLDSIKGTEI 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 393 ESELEHLR-------------VYFEKKLKDAeKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREG-----K 454
Cdd:TIGR02168 587 QGNDREILkniegflgvakdlVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggS 665
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 455 EPPDPLDLQLGQP--------KVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWE------------LSREELKREAE 514
Cdd:TIGR02168 666 AKTNSSILERRREieeleekiEELEEKIAELEKALAELRKELEELEEELEQLRKELEelsrqisalrkdLARLEAEVEQL 745
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 515 E----RLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQaAQILDLERSLMEQQGHLRQLEQELTRDdllpcsqcg 590
Cdd:TIGR02168 746 EeriaQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELRAELTLL--------- 815
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 591 QEPAMAQEEKNGALLREKEDCALQLLMAQNRfLEERKEIMEKFAKEQDAfLRDAQEKhnHELQLLQQGHQQQLLALRMEL 670
Cdd:TIGR02168 816 NEEAANLRERLESLERRIAATERRLEDLEEQ-IEELSEDIESLAAEIEE-LEELIEE--LESELEALLNERASLEEALAL 891
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 294862457 671 ETKHRSELTEQLASSESRRQALLE--THVAELQVKHNAEISALEKRHLSNLDEL 722
Cdd:TIGR02168 892 LRSELEELSEELRELESKRSELRRelEELREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1273-1399 |
2.03e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 46.77 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1273 QQEIQRLEGQLRQaarprppgprdsqcvqLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQ---EEEIKRLEETNA 1349
Cdd:COG2433 412 EEEIRRLEEQVER----------------LEAEVEELEAELEEKDERIERLERELSEARSEERREirkDREISRLDREIE 475
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 294862457 1350 SIQRQMVQLQEELEKQKKSMEELkeKEILKQENMGDLL----LTTVSRSGLDEA 1399
Cdd:COG2433 476 RLERELEEERERIEELKRKLERL--KELWKLEHSGELVpvkvVEKFTKEAIRRL 527
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
199-969 |
2.47e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.89 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 199 AELKEKLRSEMEKNAQTIETLKQDWESERELCLEnlRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSL 278
Cdd:pfam02463 165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQ--ELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 279 KNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESmktNREELN 358
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD---DEEKLK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 359 GSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEhlRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEI 438
Cdd:pfam02463 318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE--EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 439 SSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEA--EWELSREELKREAEER 516
Cdd:pfam02463 396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkLLKDELELKKSEDLLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLE-RSLMEQQGHLRQLEQELTRDDLLPCSQCGQEPAM 595
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVgGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 596 AQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKhNHELQLLQQGHQQQLLALRMELETKHR 675
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 676 SELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKK 755
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 756 ESCHRE----MLTQELENLKRQHAEELQSVRDSLRMEMSAQHIENGKGPAADLQGAHQQDPA--MALHNEGHLLVEDGDA 829
Cdd:pfam02463 715 LKLEAEellaDRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELaeEREKTEKLKVEEEKEE 794
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 830 VLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRE-LEECRAELEQLQQRREREN 908
Cdd:pfam02463 795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEeLERLEEEITKEELLQELLL 874
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294862457 909 QEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHED 969
Cdd:pfam02463 875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1046-1376 |
3.46e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1046 GLLEMALDSSKQLEEARQLhrcvEREFRHRNEEMAQAMQKQQELLERLREE-SAAKDRLALeLHTAKGLLEgfKVEK--- 1121
Cdd:COG3096 282 ELSERALELRRELFGARRQ----LAEEQYRLVEMARELEELSARESDLEQDyQAASDHLNL-VQTALRQQE--KIERyqe 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1122 ------VDLQEALGKKEESEQQLI----------LELEDLRKQL---QQAARELLT-----------LKEEKSVLWNQKE 1171
Cdd:COG3096 355 dleeltERLEEQEEVVEEAAEQLAeaearleaaeEEVDSLKSQLadyQQALDVQQTraiqyqqavqaLEKARALCGLPDL 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1172 TLTNeAKEREAALQEEVESLTRVQWESRKQ--------SEKDRATLLSQMRVLESELED-------QLVQHRGCAQLAEE 1236
Cdd:COG3096 435 TPEN-AEDYLAAFRAKEQQATEEVLELEQKlsvadaarRQFEKAYELVCKIAGEVERSQawqtareLLRRYRSQQALAQR 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1237 VATLKQQLAALDKHLRSqrqfmddqaaerehereefQQEIQRLEGQLRQaarprppgpRDSQCVQLDEEVELLQEKlrek 1316
Cdd:COG3096 514 LQQLRAQLAELEQRLRQ-------------------QQNAERLLEEFCQ---------RIGQQLDAAEELEELLAE---- 561
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1317 ldgfnelvikkdfadqqlliQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKE 1376
Cdd:COG3096 562 --------------------LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARA 601
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1141-1365 |
5.15e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 5.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1141 ELEDLRKQ------LQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMR 1214
Cdd:COG4913 243 ALEDAREQiellepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1215 VLESELEDQLVQHRG--CAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRqaarprpp 1292
Cdd:COG4913 323 EELDELEAQIRGNGGdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE-------- 394
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1293 gprdsqcvQLDEEVELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ 1365
Cdd:COG4913 395 --------ALEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
139-583 |
5.50e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 5.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 139 QANLQKEKETALTELREMLNGRRAQELALLQSRQQCE----------LELLREQHAREKEEMALRSGQEAAELKEKLRSE 208
Cdd:TIGR00618 450 TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETrkkavvlarlLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRR 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 209 MEKNAQTIETLKQDWESERELCLENLRQELSLKHQseMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA 288
Cdd:TIGR00618 530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQ--MQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 289 IKKLQED----LQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELNGSwdpv 364
Cdd:TIGR00618 608 DMLACEQhallRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQ---- 683
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 365 lAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFE--KKLKDAEKTYQEDLTVFQQRLQEAREDSLEsteisssc 442
Cdd:TIGR00618 684 -KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEieNASSSLGSDLAAREDALNQSLKELMHQART-------- 754
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 443 VLPEETSGREGKEPPDPLDLQLGQPkvQESLVEDCQVKLSKAEEKIQQMKE---EFQKKEAEWELSREELKREAEERLAS 519
Cdd:TIGR00618 755 VLKARTEAHFNNNEEVTAALQTGAE--LSHLAAEIQFFNRLREEDTHLLKTleaEIGQEIPSDEDILNLQCETLVQEEEQ 832
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 294862457 520 MFLELREKAESEkLSIISRFEHRESSMRHLQD--QQAAQILDLERSL--------MEQQGHLRQLEQELTRDDL 583
Cdd:TIGR00618 833 FLSRLEEKSATL-GEITHQLLKYEECSKQLAQltQEQAKIIQLSDKLnginqikiQFDGDALIKFLHEITLYAN 905
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1091-1288 |
6.03e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 6.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1091 ERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK 1170
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1171 ETLTNEAKEREAALQ-----EEVESLtrVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLA 1245
Cdd:COG4942 100 EAQKEELAELLRALYrlgrqPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 294862457 1246 ALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAAR 1288
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ 220
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
2244-2447 |
6.37e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.82 E-value: 6.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2244 QNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKgQALQAQQEEQQLRYLQREGQ 2323
Cdd:COG3883 22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE-IEERREELGERARALYRSGG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2324 SSRALEELKLS------------LEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAE 2391
Cdd:COG3883 101 SVSYLDVLLGSesfsdfldrlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 294862457 2392 RSRSLELSEAlqhERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELEA 2447
Cdd:COG3883 181 EALLAQLSAE---EAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1139-1587 |
6.55e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.60 E-value: 6.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1139 ILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLES 1218
Cdd:pfam12128 243 FTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRS 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1219 ELEDQLVQHRgcAQLAEEVATLKQQLAALDKhLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQlrqaarprppgpRDSQ 1298
Cdd:pfam12128 323 ELEALEDQHG--AFLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRRRSK------------IKEQ 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1299 CVQLDEEVELLQEKLREKLDgfnelvikkdfadqqlliqeeeiKRLEETNASIQRQMVQLQEELEKQKKsmeELKEKEIL 1378
Cdd:pfam12128 388 NNRDIAGIKDKLAKIREARD-----------------------RQLAVAEDDLQALESELREQLEAGKL---EFNEEEYR 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1379 KQENMGDLllttvsrsgldeagcpmlpqgsssRGPEAQPDVTERALLQHEN--EVVHRRNSEIDELKSLIENLQENQRQL 1456
Cdd:pfam12128 442 LKSRLGEL------------------------KLRLNQATATPELLLQLENfdERIERAREEQEAANAEVERLQSELRQA 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1457 QK--DKA-EEIEQLHEVIEKLQSELSlmgpKVHEVSDPQAGSLHSELA------------CLRGEGLGGQALRSELQAAQ 1521
Cdd:pfam12128 498 RKrrDQAsEALRQASRRLEERQSALD----ELELQLFPQAGTLLHFLRkeapdweqsigkVISPELLHRTDLDPEVWDGS 573
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 294862457 1522 AAKE--VFG------QLLANQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAmASQIQEFAAT 1587
Cdd:pfam12128 574 VGGElnLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK-ASREETFART 646
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1145-1483 |
6.68e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.44 E-value: 6.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1145 LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWEsRKQSEKDRATLLSQMRVLESELEdql 1224
Cdd:TIGR02169 672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE-IEQLEQEEEKLKERLEELEEDLS--- 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1225 vqhrgcaQLAEEVATLKQQLAALDKHL-RSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQaarprppgprdsqcvqLD 1303
Cdd:TIGR02169 748 -------SLEQEIENVKSELKELEARIeELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK----------------LE 804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1304 EEVELLQEKLREKLDGFNELVIKKDFAdqqlliqEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENM 1383
Cdd:TIGR02169 805 EEVSRIEARLREIEQKLNRLTLEKEYL-------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1384 GDLlltTVSRSGLDEagcpmlpqgsSSRGPEAQPDVTERAlLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEE 1463
Cdd:TIGR02169 878 RDL---ESRLGDLKK----------ERDELEAQLRELERK-IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943
|
330 340
....*....|....*....|....*....
gi 294862457 1464 ---------IEQLHEVIEKLQSELSLMGP 1483
Cdd:TIGR02169 944 eeipeeelsLEDVQAELQRVEEEIRALEP 972
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1301-1564 |
7.11e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 7.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1301 QLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELkEKEILKQ 1380
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL-RAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1381 ENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGpeaqpdVTERALLQHeneVVHRRNSEIDELKSLIENLQENQRQLQKDK 1460
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLALLLSPEDFLDA------VRRLQYLKY---LAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1461 AEeieqlhevIEKLQSELslmgpkvhevsdpqagslhselaclrgeglggQALRSELQAAQAAKEVFGQLLANQAHGHSQ 1540
Cdd:COG4942 174 AE--------LEALLAEL--------------------------------EEERAALEALKAERQKLLARLEKELAELAA 213
|
250 260
....*....|....*....|....
gi 294862457 1541 ALEALQQRLQDAEEVAARHLAELE 1564
Cdd:COG4942 214 ELAELQQEAEELEALIARLEAEAA 237
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
152-940 |
7.40e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 7.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 152 ELREMLNGRRAQELALLQSRQQcELELLREQHArekeEMALRSGQEAAELKEKLRSEMEKnAQTIETLKQDWESERELCL 231
Cdd:pfam15921 99 ELHEKQKFYLRQSVIDLQTKLQ-EMQMERDAMA----DIRRRESQSQEDLRNQLQNTVHE-LEAAKCLKEDMLEDSNTQI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 232 ENLRQeLSLKHQSEMEGLQSQFqkeLSEQKVELEKIFQAKHEAEVSLKNLeaqhQAAIKKLQEDLQSEhCQYLQ------ 305
Cdd:pfam15921 173 EQLRK-MMLSHEGVLQEIRSIL---VDFEEASGKKIYEHDSMSTMHFRSL----GSAISKILRELDTE-ISYLKgrifpv 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 306 --DLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELNGSWDPVLAQAS--------HLEELE 375
Cdd:pfam15921 244 edQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARnqnsmymrQLSDLE 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 376 HLRSgfaqqqqqeraQHESELEHLRVYFEKKLKDAEKtyqeDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKE 455
Cdd:pfam15921 324 STVS-----------QLRSELREAKRMYEDKIEELEK----QLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 456 PPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEERLASmfleLREKAES-EKLS 534
Cdd:pfam15921 389 REKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAA----IQGKNESlEKVS 464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 535 -IISRFEHRESSMRHLQDQQAAQILDLERSlmeqqghlrqleqELTRDDLlpcSQCGQEPAMAQEEKNGAL--LREKEDC 611
Cdd:pfam15921 465 sLTAQLESTKEMLRKVVEELTAKKMTLESS-------------ERTVSDL---TASLQEKERAIEATNAEItkLRSRVDL 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 612 ALQLLmaqnRFLEERKEIMEKFAKEQDAFLRDAQEKhnhelqLLQQGHQQQLLALRMELETKH-RSELTEQLASSE---- 686
Cdd:pfam15921 529 KLQEL----QHLKNEGDHLRNVQTECEALKLQMAEK------DKVIEILRQQIENMTQLVGQHgRTAGAMQVEKAQleke 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 687 --SRRQALLETHVaeLQVKHNAEISALEKRhLSNLdELESCYVADVQTirdEHQQALELLRAELEEQLQKKESCHREM-- 762
Cdd:pfam15921 599 inDRRLELQEFKI--LKDKKDAKIRELEAR-VSDL-ELEKVKLVNAGS---ERLRAVKDIKQERDQLLNEVKTSRNELns 671
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 763 LTQELENLKRQ---HAEELQSVRDSLRMEM-SAQ-HIENGKGPAADLQGAHQQDPAMALHNEGHLLVEDG--DAVLRSVD 835
Cdd:pfam15921 672 LSEDYEVLKRNfrnKSEEMETTTNKLKMQLkSAQsELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGqiDALQSKIQ 751
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 836 aegLLHQAGPQELGDAHTVEMQKSQ--AELAK--------PQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRE 905
Cdd:pfam15921 752 ---FLEEAMTNANKEKHFLKEEKNKlsQELSTvateknkmAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828
|
810 820 830
....*....|....*....|....*....|....*.
gi 294862457 906 RENQEGTTLICMLRADLELAQGEGKALRDALR-RLL 940
Cdd:pfam15921 829 RQEQESVRLKLQHTLDVKELQGPGYTSNSSMKpRLL 864
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
134-358 |
8.07e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 8.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 134 QLELTQANlqkekeTALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEmalrsgqeaaelKEKLRSEMEKNA 213
Cdd:TIGR04523 273 QKELEQNN------KKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKK------------LEEIQNQISQNN 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 214 QTIETLKQDweserelcLENLRQELSlkhqsEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQ 293
Cdd:TIGR04523 335 KIISQLNEQ--------ISQLKKELT-----NSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQ 401
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 294 EDlqsehcqylQDLEQKFREKEKAKELELETLQASYEDLKAQ---SQEEIRLLWSQLESMKTNREELN 358
Cdd:TIGR04523 402 NQ---------EKLNQQKDEQIKKLQQEKELLEKEIERLKETiikNNSEIKDLTNQDSVKELIIKNLD 460
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2199-2509 |
8.76e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 8.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2199 HQLRRQVELLAykveQEKCIANELQKTLSK----EQETASDVRKRLVVEQNAVQDLKS-ELHACKQENTSLLESLDKVQQ 2273
Cdd:PTZ00121 1264 HFARRQAAIKA----EEARKADELKKAEEKkkadEAKKAEEKKKADEAKKKAEEAKKAdEAKKKAEEAKKKADAAKKKAE 1339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2274 EVLRLRAVLDGKEKELKVVLEELEsERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHER 2353
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAE-EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2354 AAkDNLQKElqieasrceallAQEKGQLSELQKslEAERSRSLELSEALQHERLLTEQLSRNSQEACARQEtqvqhalLR 2433
Cdd:PTZ00121 1419 KA-DEAKKK------------AEEKKKADEAKK--KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE-------AK 1476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2434 KLKAEKTRALELEAMLEKVQKQAahTQQQLEAQAQERCVELRREKE-------RELEIQRQRDEHKIEQLQRLVRELRWK 2506
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKA--DEAKKAAEAKKKADEAKKAEEakkadeaKKAEEAKKADEAKKAEEKKKADELKKA 1554
|
...
gi 294862457 2507 EEV 2509
Cdd:PTZ00121 1555 EEL 1557
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2072-2297 |
9.76e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 9.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2072 QALSEVTT---DKGEKESLETH-----LTWSEELLRAIQEVFAREQEKAELQPRPYGSNLGDYNSLVQRLEKVIQEQGdp 2143
Cdd:TIGR02169 272 QLLEELNKkikDLGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER-- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2144 qkvqdhlclSDRSSLLAEIQALRAQLRMTHLQNQEKlqqlcaaltSTEARGSQREH-QLRRQVELLAYKVEQEKCIANEL 2222
Cdd:TIGR02169 350 ---------KRRDKLTEEYAELKEELEDLRAELEEV---------DKEFAETRDELkDYREKLEKLKREINELKRELDRL 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2223 QKTLSKEQETASDVR---KRLVVEQNAVQ----DLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEE 2295
Cdd:TIGR02169 412 QEELQRLSEELADLNaaiAGIEAKINELEeekeDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
..
gi 294862457 2296 LE 2297
Cdd:TIGR02169 492 LA 493
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1181-1592 |
9.90e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 9.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1181 EAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFmdD 1260
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL--L 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1261 QAAEREHEREEFQQEIQRLEGQLRQA-ARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNeLVIKKDFADQQLLIQE- 1338
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELeERLEELRELEEELEELEAELAELQEELEELLEQLS-LATEEELQDLAEELEEl 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1339 -EEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE---------------NMGDLLLTTVSRSGLDEAGCP 1402
Cdd:COG4717 205 qQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallgLGGSLLSLILTIAGVLFLVLG 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1403 MLPQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKS---LIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELS 1479
Cdd:COG4717 285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalgLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1480 LMGPKVHEVSDPQAGSLHSElaclrgeglggQALRSELQAAQAAKEVFGQLLANQAHGHSQALEALQQRLQDAEEVAARH 1559
Cdd:COG4717 365 LEELEQEIAALLAEAGVEDE-----------EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433
|
410 420 430
....*....|....*....|....*....|...
gi 294862457 1560 LAELEHCVALREAEVEAMASQIQEFAATLKAKE 1592
Cdd:COG4717 434 LEELEEELEELEEELEELREELAELEAELEQLE 466
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1031-1368 |
1.03e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.94 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1031 QPIRRVYQSLSTAVEGLLEMALDSS--KQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELH 1108
Cdd:COG3096 809 QKLQRLHQAFSQFVGGHLAVAFAPDpeAELAALRQRRSELEREL----AQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAN 884
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1109 TakgLLEGFKVEKVD-LQEALGKKEESEQQL------ILELEDLRKQLQ-------QAARELLTLKEEKSVLWNQKETLT 1174
Cdd:COG3096 885 L---LADETLADRLEeLREELDAAQEAQAFIqqhgkaLAQLEPLVAVLQsdpeqfeQLQADYLQAKEQQRRLKQQIFALS 961
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1175 NEAKEREA-ALQEEVESLTrvqwESRKQSEKDRAtllsQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRS 1253
Cdd:COG3096 962 EVVQRRPHfSYEDAVGLLG----ENSDLNEKLRA----RLEQAEEARREAREQLR---QAQAQYSQYNQVLASLKSSRDA 1030
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1254 QRQFMDDqaaerehereeFQQEIQRLEgqlrqaarprppgprdsqcVQLDEEVEllqEKLREKLDGFNELVI----KKDF 1329
Cdd:COG3096 1031 KQQTLQE-----------LEQELEELG-------------------VQADAEAE---ERARIRRDELHEELSqnrsRRSQ 1077
|
330 340 350
....*....|....*....|....*....|....*....
gi 294862457 1330 ADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKS 1368
Cdd:COG3096 1078 LEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAG 1116
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2120-2502 |
1.06e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2120 GSNLGDYNSLVQR--LEKVIQEQGDPQKVQDHL--CLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLcAALTSTEARGS 2195
Cdd:TIGR02169 658 GSRAPRGGILFSRsePAELQRLRERLEGLKRELssLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLK 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2196 QREHQLRR-----QVELLAYKVEQEKCIAN--ELQKTLSKEQETASDVRKRLVVEQ-NAVQDLKSELHACKQENTSLLES 2267
Cdd:TIGR02169 737 ERLEELEEdlsslEQEIENVKSELKELEARieELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2268 LDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKgqalqaqqeeqqlryLQREGQSSRA-LEELKLSLEKQLAQNNQLC 2346
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS---------------IEKEIENLNGkKEELEEELEELEAALRDLE 881
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2347 VALKHERAAKDNLQKELQieasrceallaQEKGQLSELQKSLEAERSRSLELSEALQherLLTEQLSRNSQEACARQETQ 2426
Cdd:TIGR02169 882 SRLGDLKKERDELEAQLR-----------ELERKIEELEAQIEKKRKRLSELKAKLE---ALEEELSEIEDPKGEDEEIP 947
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 294862457 2427 VQHALLRKLKAEKTRALELEAMLEKVQKQAahtqQQLEAQAQERCVELrREKERELEIQRQRDEHKIEQLQRLVRE 2502
Cdd:TIGR02169 948 EEELSLEDVQAELQRVEEEIRALEPVNMLA----IQEYEEVLKRLDEL-KEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
176-431 |
1.10e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 176 LELLREQHAREKEEMAlrsgqEAAELKEKLRSEMEKNAQTIETLKQ---------DWES-ERELclENLRQELS--LKHQ 243
Cdd:COG4913 612 LAALEAELAELEEELA-----EAEERLEALEAELDALQERREALQRlaeyswdeiDVASaEREI--AELEAELErlDASS 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 244 SEMEGLQSQF---QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDLEQKFREkEKAKEL 320
Cdd:COG4913 685 DDLAALEEQLeelEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAA-ALGDAV 763
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 321 ElETLQASYEDLKAQSQEEIRLLWSQLESMKT--NRE--ELNGSWDPVLAQASH-LEELEHLRsgfaqqqqqeraqhESE 395
Cdd:COG4913 764 E-RELRENLEERIDALRARLNRAEEELERAMRafNREwpAETADLDADLESLPEyLALLDRLE--------------EDG 828
|
250 260 270
....*....|....*....|....*....|....*..
gi 294862457 396 LEHlrvyFEKKLKDA-EKTYQEDLTVFQQRLQEARED 431
Cdd:COG4913 829 LPE----YEERFKELlNENSIEFVADLLSKLRRAIRE 861
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1051-1294 |
1.34e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1051 ALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEgfkvekvDLQEALGK 1130
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-------ALEAELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1131 KEESEQQLILELEDLRKQLQQAARELLTLKEEKSVlwnqKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLL 1210
Cdd:COG4942 88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPL----ALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1211 SQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPR 1290
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
....
gi 294862457 1291 PPGP 1294
Cdd:COG4942 244 PAAG 247
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
203-349 |
1.38e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 203 EKLRSEMEKNAQTIetLKqdwESERELclENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNle 282
Cdd:PRK12704 30 EAKIKEAEEEAKRI--LE---EAKKEA--EAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR-- 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 294862457 283 aqHQAAIKKLQEDLQSEhcqyLQDLEQKFREKEKaKELELETLQASY----EDLKAQSQEEIR-LLWSQLES 349
Cdd:PRK12704 101 --KLELLEKREEELEKK----EKELEQKQQELEK-KEEELEELIEEQlqelERISGLTAEEAKeILLEKVEE 165
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1084-1477 |
1.58e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.24 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1084 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 1163
Cdd:TIGR04523 225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQK 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1164 SVLWNQ--KETLTNEAKEREAA-------------LQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESELEDQLVQHr 1228
Cdd:TIGR04523 305 EQDWNKelKSELKNQEKKLEEIqnqisqnnkiisqLNEQISQLKK----ELTNSESENSEKQRELEEKQNEIEKLKKEN- 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1229 gcAQLAEEVATLKQQLAALDKHLRSQR---QFMDDQAAEREHEREEFQQEIQRLEgqlrqaarprppgprdSQCVQLDEE 1305
Cdd:TIGR04523 380 --QSYKQEIKNLESQINDLESKIQNQEklnQQKDEQIKKLQQEKELLEKEIERLK----------------ETIIKNNSE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1306 VELLQEKLREKLDGFNELVIKKDfadqqllIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD 1385
Cdd:TIGR04523 442 IKDLTNQDSVKELIIKNLDNTRE-------SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1386 LLlttvsrsgldeagcpmlPQGSSSRgpeaqpdVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKD-KAEEI 1464
Cdd:TIGR04523 515 LT-----------------KKISSLK-------EKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDeKNKEI 570
|
410
....*....|...
gi 294862457 1465 EQLHEVIEKLQSE 1477
Cdd:TIGR04523 571 EELKQTQKSLKKK 583
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1467-1603 |
1.62e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 43.42 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1467 LHEVIEKLQSELSLMGPKVHEVSD------PQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLANQAHGHSQ 1540
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADllslerQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1541 ALEALQQrlqdaeeVAARHLAElehcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEID 1603
Cdd:PRK09039 124 ELDSEKQ-------VSARALAQ----VELLNQQIAALRRQLAALEAALDASEKRDRESQAKIA 175
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1125-1387 |
1.86e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.79 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1125 QEALGKKEESEQQLILELEDLRKQLQQAARELL----TLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWEsrk 1200
Cdd:COG5185 267 LEKLGENAESSKRLNENANNLIKQFENTKEKIAeytkSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTA--- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1201 QSEKDRATLLSQMRVLESELEdQLVQHRGCAQLAEEVATLKQQLAALDKHL----RSQRQFMDDQAAEREHEREEFQQEI 1276
Cdd:COG5185 344 EIEQGQESLTENLEAIKEEIE-NIVGEVELSKSSEELDSFKDTIESTKESLdeipQNQRGYAQEILATLEDTLKAADRQI 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1277 QRLEGQLRQAARprppgprdsqcvqldeEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE--EEIKRLEETNASIQRQ 1354
Cdd:COG5185 423 EELQRQIEQATS----------------SNEEVSKLLNELISELNKVMREADEESQSRLEEAydEINRSVRSKKEDLNEE 486
|
250 260 270
....*....|....*....|....*....|...
gi 294862457 1355 MVQLQEELEKQKKSMEELKEKEILKQENMGDLL 1387
Cdd:COG5185 487 LTQIESRVSTLKATLEKLRAKLERQLEGVRSKL 519
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2223-2508 |
1.95e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2223 QKTLSKEQETasdvRKRLVVEQNAVQDLKSELhACKQENTSLLESLDKVQQEVLRLRAVLDGkEKELKVVLEELESERGK 2302
Cdd:pfam17380 281 QKAVSERQQQ----EKFEKMEQERLRQEKEEK-AREVERRRKLEEAEKARQAEMDRQAAIYA-EQERMAMERERELERIR 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2303 GQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLS 2382
Cdd:pfam17380 355 QEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2383 ELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELE--------AMLEKVQK 2454
Cdd:pfam17380 435 REVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEkeleerkqAMIEEERK 514
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 294862457 2455 QAAHTQQQLEAQAQERCVELRREKERELEIQRQRDEHK-IEQLQRLVRELRWKEE 2508
Cdd:pfam17380 515 RKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRrIQEQMRKATEERSRLE 569
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2072-2544 |
1.95e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2072 QALSEVTTDKGEKESLETHLTWSEELLRAIQEVFAREQEKAELQPRPYGSNLGDYNSLVQRLEKVIQEQGDPQKVQDHLc 2151
Cdd:COG1196 327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2152 LSDRSSLLAEIQALRAQLRmTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANELQKTLSKEQE 2231
Cdd:COG1196 406 EEAEEALLERLERLEEELE-ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2232 TASDVRKRLVVEQNAVQDLKSELHAckqentSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKGQALQAQQE 2311
Cdd:COG1196 485 ELAEAAARLLLLLEAEADYEGFLEG------VKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2312 EQQLRYLQREGQSSRAlEELKLSLEKQLAQNNQLCVALKHERAAkdNLQKELQIEASRCEALLAQEKGQLSELQKSLEAE 2391
Cdd:COG1196 559 AAAAIEYLKAAKAGRA-TFLPLDKIRARAALAAALARGAIGAAV--DLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2392 RSRSLELSEALQHERLLTEQLSRNSQEAcaRQETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERC 2471
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGEGGSAGGSLT--GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 2472 VELRREKERELEIQRQRDEHKIEQLQRLVRELrwKEEVSGGNGPCRGSPGRGSLERDQFqeqqqeleKIRQQL 2544
Cdd:COG1196 714 EERLEEELEEEALEEQLEAEREELLEELLEEE--ELLEEEALEELPEPPDLEELERELE--------RLEREI 776
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
119-551 |
2.17e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 119 ELEALRLSLNNMHTAQLELTQANLQKEK--------ETALTELREMLNGRRAQELALLQSRQQCE-----------LELL 179
Cdd:PRK03918 222 ELEKLEKEVKELEELKEEIEELEKELESlegskrklEEKIRELEERIEELKKEIEELEEKVKELKelkekaeeyikLSEF 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 180 REQHAREKEEMALRSG---QEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQEL---SLKHQSEMEGLQSQF 253
Cdd:PRK03918 302 YEEYLDELREIEKRLSrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeAKAKKEELERLKKRL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 254 Q-KELSEQKVELEKIFQAKHEAEV----------SLKNLEAQHQAAIKKLQE----------DLQSEHcqyLQDLEQKFR 312
Cdd:PRK03918 382 TgLTPEKLEKELEELEKAKEEIEEeiskitarigELKKEIKELKKAIEELKKakgkcpvcgrELTEEH---RKELLEEYT 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 313 EKEKAKELELETLQASYEDLKAQ---------SQEEIRLLWSQLESMKTNREELNGSWDPVLAQAShlEELEHLRSGFAQ 383
Cdd:PRK03918 459 AELKRIEKELKEIEEKERKLRKElrelekvlkKESELIKLKELAEQLKELEEKLKKYNLEELEKKA--EEYEKLKEKLIK 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 384 -----QQQQERAQHESELEHLRVYFEKKLKDAEktyqEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:PRK03918 537 lkgeiKSLKKELEKLEELKKKLAELEKKLDELE----EELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 459 PLdlqlgqpKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISR 538
Cdd:PRK03918 613 EL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685
|
490
....*....|...
gi 294862457 539 FEHRESSMRHLQD 551
Cdd:PRK03918 686 EKRREEIKKTLEK 698
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2138-2447 |
2.75e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2138 QEQGDPQKVQDHLCLSDRSSLLAEIQAlRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRqVELLAYKVEQEKC 2217
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER-IRQEERKRELERI 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2218 IANELQKTLSKEQETasdvrKRLVVE-QNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRAVLDGKEKELKVVLEEL 2296
Cdd:pfam17380 366 RQEEIAMEISRMREL-----ERLQMErQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRL 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2297 ESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQlAQNNQLCVALKH---ERAAKDNLQKELQIEASR--CE 2371
Cdd:pfam17380 441 EEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKE-KRDRKRAEEQRRkilEKELEERKQAMIEEERKRklLE 519
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 294862457 2372 ALLAQEKGQLSELQKSLEAERSRSLElsEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELEA 2447
Cdd:pfam17380 520 KEMEERQKAIYEEERRREAEEERRKQ--QEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA 593
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1056-1478 |
3.42e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 3.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1056 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLA-----LELHTAKGLLEGFKVEKVDLQEALGK 1130
Cdd:PRK03918 391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPvcgreLTEEHRKELLEEYTAELKRIEKELKE 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1131 KEESEQQLILELEDLRKQLQQAaRELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqsEKDRATLL 1210
Cdd:PRK03918 471 IEEKERKLRKELRELEKVLKKE-SELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKL-----------KEKLIKLK 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1211 SQMRVLESELEdqlvqhrgcaqlaeEVATLKQQLAALDKHLRSqrqfmddqaaerehereeFQQEIQRLEGQLRQAARpr 1290
Cdd:PRK03918 539 GEIKSLKKELE--------------KLEELKKKLAELEKKLDE------------------LEEELAELLKELEELGF-- 584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1291 ppgprdsqcvqldEEVELLQEKLREKLDGFNELVIKKDfADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSME 1370
Cdd:PRK03918 585 -------------ESVEELEERLKELEPFYNEYLELKD-AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1371 ELKEK-EILKQENMGDLLLTTVSR-SGLDEagcpmlpqgsSSRGPEAQPDVTERAL--LQHENEVVHRRNSEIDELKSLI 1446
Cdd:PRK03918 651 ELEKKySEEEYEELREEYLELSRElAGLRA----------ELEELEKRREEIKKTLekLKEELEEREKAKKELEKLEKAL 720
|
410 420 430
....*....|....*....|....*....|..
gi 294862457 1447 ENLQENQRQLQKDKAEEIEQLHEVIEKLQSEL 1478
Cdd:PRK03918 721 ERVEELREKVKKYKALLKERALSKVGEIASEI 752
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
855-1256 |
3.85e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 3.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 855 EMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEgttlicMLRADLELAQGEGKALRD 934
Cdd:COG4717 180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE------LEAAALEERLKEARLLLL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 935 ALRRLLDLFGdtlkAAVTLKSRISERAGLLLdhedaadtsdARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISsh 1014
Cdd:COG4717 254 IAAALLALLG----LGGSLLSLILTIAGVLF----------LVLGLLALLFLLLAREKASLGKEAEELQALPALEELE-- 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1015 vcesffispentldcEQPIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVERefrhrneemaqamQKQQELLERLR 1094
Cdd:COG4717 318 ---------------EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE-------------LEEELQLEELE 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1095 EESAAkdrlalelhtakgLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTL--KEEKSVLWNQKET 1172
Cdd:COG4717 370 QEIAA-------------LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEE 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1173 LTNEAKEREAALQEEVESLTRVQWESRKQSEKDRatlLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQLAALDKHLR 1252
Cdd:COG4717 437 LEEELEELEEELEELREELAELEAELEQLEEDGE---LAELLQELEELKAEL------RELAEEWAALKLALELLEEARE 507
|
....
gi 294862457 1253 SQRQ 1256
Cdd:COG4717 508 EYRE 511
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
2127-2508 |
4.53e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.80 E-value: 4.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2127 NSLVQRLEkVIQEQGDPQKVQDHLCLSDRSSLLAEIQA-LRAQLRMTHLQNQEKLQQLCAALTS-TEARG-----SQREH 2199
Cdd:pfam15921 295 NSIQSQLE-IIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSElTEARTerdqfSQESG 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2200 QLRRQVE-LLA--YKVEQEKCIANELQKTL----SKEQETASDVRKRLVVEQNAVQDLKSELHACKQE-------NTSLL 2265
Cdd:pfam15921 374 NLDDQLQkLLAdlHKREKELSLEKEQNKRLwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcqgqmerQMAAI 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2266 ESLDKVQQEVLRLRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREgqssRALEELKLSLEKQLAQNNQL 2345
Cdd:pfam15921 454 QGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKE----RAIEATNAEITKLRSRVDLK 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2346 CVALKHERAAKDNLQkELQIEasrCEALlaqeKGQLSELQKSLEAERSRSLELSEAL-QHERLLTEQLSRNSQ---EACA 2421
Cdd:pfam15921 530 LQELQHLKNEGDHLR-NVQTE---CEAL----KLQMAEKDKVIEILRQQIENMTQLVgQHGRTAGAMQVEKAQlekEIND 601
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2422 RQETQVQHALLRKLKAEKTRALELEAM---LEKVQKQAAHTQQQLEAQaqercvELRREKEREL-EIQRQRDE--HKIEQ 2495
Cdd:pfam15921 602 RRLELQEFKILKDKKDAKIRELEARVSdleLEKVKLVNAGSERLRAVK------DIKQERDQLLnEVKTSRNElnSLSED 675
|
410
....*....|...
gi 294862457 2496 LQRLVRELRWKEE 2508
Cdd:pfam15921 676 YEVLKRNFRNKSE 688
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1014-1311 |
5.60e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.63 E-value: 5.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1014 HVCESFFISPENTLDCEQPIRRVYQSLSTAVEGL---LEMALDSSKQLEEARQLHRCVEREFrhrneEMAQAMQKQQELL 1090
Cdd:COG3096 427 ALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELeqkLSVADAARRQFEKAYELVCKIAGEV-----ERSQAWQTARELL 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1091 ERLREESAAKDRLalelhtakgllegfkvekvdlqealgkkeeseQQLILELEDLRKQL--QQAARELLtlkEEKSVLWN 1168
Cdd:COG3096 502 RRYRSQQALAQRL--------------------------------QQLRAQLAELEQRLrqQQNAERLL---EEFCQRIG 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1169 QKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLlSQMRVLESELED--------QLVQHRGCAQLAEEVATL 1240
Cdd:COG3096 547 QQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL-EQLRARIKELAArapawlaaQDALERLREQSGEALADS 625
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 294862457 1241 KQQLAALDKHLRSQRQFmddqaaerEHEREEFQQEIQRLEGQLRQAArpRPPGPRDSQCVQLDEEV--ELLQE 1311
Cdd:COG3096 626 QEVTAAMQQLLEREREA--------TVERDELAARKQALESQIERLS--QPGGAEDPRLLALAERLggVLLSE 688
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1056-1479 |
5.87e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 5.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1056 KQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 1135
Cdd:PRK03918 186 KRTENIEELIKEKEKEL----EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1136 QQL---ILELEDLRKQLQQAARELLTLKEEK------SVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKdr 1206
Cdd:PRK03918 262 RELeerIEELKKEIEELEEKVKELKELKEKAeeyiklSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER-- 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1207 atlLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKH---------------LRSQRQFMDDQAAEREHEREE 1271
Cdd:PRK03918 340 ---LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltgltpeklekeleeLEKAKEEIEEEISKITARIGE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1272 FQQEIQRLEG---QLRQAARPRPPGPRdsqcvQLDEEVEL-LQEKLREKLDGFNELVIKKDFADQQLLIQEEEI--KRLE 1345
Cdd:PRK03918 417 LKKEIKELKKaieELKKAKGKCPVCGR-----ELTEEHRKeLLEEYTAELKRIEKELKEIEEKERKLRKELRELekVLKK 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1346 ETNASIQRQMVQLQEELEKQKKS--MEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPDVTERA 1423
Cdd:PRK03918 492 ESELIKLKELAEQLKELEEKLKKynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE 571
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 294862457 1424 LLQHENEVVHRRNSEIDELKSLIENLQENQRQL--QKDKAEEIEQLHEVIEKLQSELS 1479
Cdd:PRK03918 572 LAELLKELEELGFESVEELEERLKELEPFYNEYleLKDAEKELEREEKELKKLEEELD 629
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1070-1227 |
6.36e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 6.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1070 REFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGfkvekvDLQEALGKKEESEQQLIL-----ELED 1144
Cdd:COG1579 20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLEL------EIEEVEARIKKYEEQLGNvrnnkEYEA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1145 LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQ---SEKDRATLLSQMRVLESELE 1221
Cdd:COG1579 94 LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEElaeLEAELEELEAEREELAAKIP 173
|
....*.
gi 294862457 1222 DQLVQH 1227
Cdd:COG1579 174 PELLAL 179
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
144-294 |
6.51e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 6.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 144 KEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQ--EAAELKEKLRSEMEKN-AQTIETLK 220
Cdd:COG4913 265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARldALREELDELEAQIRGNgGDRLEQLE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 221 QD---WESERELCLENLRQ--------ELSLKH-QSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA 288
Cdd:COG4913 345 REierLERELEERERRRARleallaalGLPLPAsAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424
|
....*.
gi 294862457 289 IKKLQE 294
Cdd:COG4913 425 EAEIAS 430
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1056-1575 |
7.51e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 7.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1056 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREE----------SAAKDRLALELHTAKGLLEGFKVEKVDLQ 1125
Cdd:TIGR00618 229 KHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIeelraqeavlEETQERINRARKAAPLAAHIKAVTQIEQQ 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1126 EA-----LGKKEESEQQLILELEDLRKQ---LQQAARELLTL--KEEKSVLWNQKETLTNEAKEREAALQEEVESLTRvQ 1195
Cdd:TIGR00618 309 AQrihteLQSKMRSRAKLLMKRAAHVKQqssIEEQRRLLQTLhsQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQ-Q 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1196 WESRKQSEKDRATLLSQMRVL----------ESELEDQLVQHRGCAQLAEEVATLKQQLAA--------LDKHLRSQRQF 1257
Cdd:TIGR00618 388 KTTLTQKLQSLCKELDILQREqatidtrtsaFRDLQGQLAHAKKQQELQQRYAELCAAAITctaqceklEKIHLQESAQS 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1258 MDDQAAEREHEREEFQQ--EIQRLEGQ--LRQAARPRP-----------------PGPRDSQCVQLDEEVELLQE----- 1311
Cdd:TIGR00618 468 LKEREQQLQTKEQIHLQetRKKAVVLArlLELQEEPCPlcgscihpnparqdidnPGPLTRRMQRGEQTYAQLETseedv 547
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1312 --KLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ---KKSMEELKEKEILKQENMGDL 1386
Cdd:TIGR00618 548 yhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLseaEDMLACEQHALLRKLQPEQDL 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1387 LLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPDVTERALL--QHENEVVHRRNSEIDELKSLIenlqenqRQLQKDKaEEI 1464
Cdd:TIGR00618 628 QDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSirVLPKELLASRQLALQKMQSEK-------EQLTYWK-EML 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1465 EQLHEVIEKLQSELSLMGPKVHEVSDpqagSLHSELACLRGEGLGGQALRSELQAAQAAKEvfgQLLANQAHGHSQALEA 1544
Cdd:TIGR00618 700 AQCQTLLRELETHIEEYDREFNEIEN----ASSSLGSDLAAREDALNQSLKELMHQARTVL---KARTEAHFNNNEEVTA 772
|
570 580 590
....*....|....*....|....*....|....*..
gi 294862457 1545 LQQRLQDAEEVAA------RHLAELEHCVALREAEVE 1575
Cdd:TIGR00618 773 ALQTGAELSHLAAeiqffnRLREEDTHLLKTLEAEIG 809
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
689-1256 |
7.97e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 7.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 689 RQALLEthvAELQVKHNAEISALEKRHLSNLDELESCyVADVQTIRDEHQQALELLRAELEEQLQKKeschREMLTQELE 768
Cdd:COG4913 241 HEALED---AREQIELLEPIRELAERYAAARERLAEL-EYLRAALRLWFAQRRLELLEAELEELRAE----LARLEAELE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 769 NLKRQHaEELQSVRDSLRmemsAQHIENGKGPAADLQgaHQQDpamalhnegHLLVEDGDAVLRSVDAEGLLHQAGPQEL 848
Cdd:COG4913 313 RLEARL-DALREELDELE----AQIRGNGGDRLEQLE--REIE---------RLERELEERERRRARLEALLAALGLPLP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 849 GDAHTVEMQKSQAELAK---PQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEGTTLICMLRADLELA 925
Cdd:COG4913 377 ASAEEFAALRAEAAALLealEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLD 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 926 QGE---------------------GKALRDALRRLL---DLFGDTLKA--AVTLKSRI-SERAGLLLDHEDAADTSDARL 978
Cdd:COG4913 457 EAElpfvgelievrpeeerwrgaiERVLGGFALTLLvppEHYAAALRWvnRLHLRGRLvYERVRTGLPDPERPRLDPDSL 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 979 AaaalgdmwsdeGLLEIDRTLPEGAETSSVCEISSHVC---------ESFFISPENTL---------DCEQPIRRVYQsl 1040
Cdd:COG4913 537 A-----------GKLDFKPHPFRAWLEAELGRRFDYVCvdspeelrrHPRAITRAGQVkgngtrhekDDRRRIRSRYV-- 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1041 staveglleMALDSSKQLEEARQLHRCVEREfRHRNEEMAQAMQKQQELLERLREESAAkdrlalelhtakglLEGFKVE 1120
Cdd:COG4913 604 ---------LGFDNRAKLAALEAELAELEEE-LAEAEERLEALEAELDALQERREALQR--------------LAEYSWD 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1121 KVDLQEAlgkkeeseQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLT---NEAKEREAALQEEVESLTRVQwe 1197
Cdd:COG4913 660 EIDVASA--------EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEeelDELKGEIGRLEKELEQAEEEL-- 729
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 294862457 1198 SRKQSEKDRATLLSQmRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQ 1256
Cdd:COG4913 730 DELQDRLEAAEDLAR-LELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1118-1377 |
8.02e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 8.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1118 KVEKVDLQEAL---GKKEESEQqlilELEDLRKQLQQAARELLTLKEEksvLWNQKETLTNEAKER---------EAALQ 1185
Cdd:PRK11281 59 KLVQQDLEQTLallDKIDRQKE----ETEQLKQQLAQAPAKLRQAQAE---LEALKDDNDEETRETlstlslrqlESRLA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1186 EEVESLTRVQWE----------SRKQSEKDRATLLS-QMRVLesELEDQL--VQHRGCAQLAEEVATLKQQLAALDKHLR 1252
Cdd:PRK11281 132 QTLDQLQNAQNDlaeynsqlvsLQTQPERAQAALYAnSQRLQ--QIRNLLkgGKVGGKALRPSQRVLLQAEQALLNAQND 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 1253 SQRQFMDDQAAEREHEREefqqeiQRLEGQLRQAarprppgprdsqcvQLDEEVELLQEKLREK-LDGFNELVikkdfad 1331
Cdd:PRK11281 210 LQRKSLEGNTQLQDLLQK------QRDYLTARIQ--------------RLEHQLQLLQEAINSKrLTLSEKTV------- 262
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 294862457 1332 QQLLIQEEEIKrlEETNASIQRQM---VQLQEELEKQKKSMEELKEKEI 1377
Cdd:PRK11281 263 QEAQSQDEAAR--IQANPLVAQELeinLQLSQRLLKATEKLNTLTQQNL 309
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
73-399 |
9.58e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.56 E-value: 9.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 73 PSCSNTLEGTRGASAAQEQ----EDCELDVTDLQGQQQTQPPPPQTAHSL---ELEALRLSLNNMHTAQLELTQANLQKE 145
Cdd:PRK02224 455 PECGQPVEGSPHVETIEEDrervEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIEE 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 146 KETALTELREmlngrRAQELallqsrqQCELELLREQhAREKEEMALRSGQEAAELKEKLrsemEKNAQTIETLKQDWES 225
Cdd:PRK02224 535 KRERAEELRE-----RAAEL-------EAEAEEKREA-AAEAEEEAEEAREEVAELNSKL----AELKERIESLERIRTL 597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 226 ERELclENLRQELS-----LKHQSEMEGLQSQFQKELSEQKVELEKIFQAkheaevslknleaqhqAAIKKLQEDLQSEH 300
Cdd:PRK02224 598 LAAI--ADAEDEIErlrekREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEEAREDKERAE 659
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 301 cQYLQDLEQKFREKEKAKEleletlqasyeDLkaqsQEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSG 380
Cdd:PRK02224 660 -EYLEQVEEKLDELREERD-----------DL----QAEIGAVENELEELEELRERREALENRVEALEALYDEAEELESM 723
|
330
....*....|....*....
gi 294862457 381 FAQQQQQERAQHESELEHL 399
Cdd:PRK02224 724 YGDLRAELRQRNVETLERM 742
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2285-2504 |
9.58e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 9.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2285 KEKELKVVLEELESERgkgqALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVA-LKHERAAKDNLQKEL 2363
Cdd:pfam02463 171 KKEALKKLIEETENLA----ELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDyLKLNEERIDLLQELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2364 QIEASRCEALLAQEKGQLSELQKSLEAERSRslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRAL 2443
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294862457 2444 ELEAMLEKVQKQAAHTQQQLEAQAQERcvELRREKERELEIQRQRDEHKIEQLQRLVRELR 2504
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEIKR--EAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
2178-2431 |
9.67e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 41.58 E-value: 9.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2178 EKLQQLCAALTS-TEARGSQREHQLRRQVellaykVEQEKCIANELQKTLSKEQETASDVRKRLvveqnAVQDLKSELha 2256
Cdd:PRK10929 45 EIVEALQSALNWlEERKGSLERAKQYQQV------IDNFPKLSAELRQQLNNERDEPRSVPPNM-----STDALEQEI-- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2257 cKQENTSLLESLDKVQQEVLRLRAVLD------GKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRA-LE 2329
Cdd:PRK10929 112 -LQVSSQLLEKSRQAQQEQDRAREISDslsqlpQQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKAlVD 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294862457 2330 ELKLSlekQLAQNN-QLCVALKHERAAKDNLQKELQIEASRC--------EA--------LLAQEKGQLSE-LQKSLEAE 2391
Cdd:PRK10929 191 ELELA---QLSANNrQELARLRSELAKKRSQQLDAYLQALRNqlnsqrqrEAeralesteLLAEQSGDLPKsIVAQFKIN 267
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 294862457 2392 RSRSLELSEALQHERLLTEQlsrnsQEACARQETQVQHAL 2431
Cdd:PRK10929 268 RELSQALNQQAQRMDLIASQ-----QRQAASQTLQVRQAL 302
|
|
| |
