|
Name |
Accession |
Description |
Interval |
E-value |
| hisC |
TIGR01141 |
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ... |
11-371 |
8.19e-176 |
|
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]
Pssm-ID: 273467 Cd Length: 350 Bit Score: 492.55 E-value: 8.19e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 11 RDVVKKLKPYVPGkskeeiARAYGIKpeDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDE 90
Cdd:TIGR01141 1 RPDIKNLSPYQPG------ARELGGD--EVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 91 ENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFL 170
Cdd:TIGR01141 73 EQILLG-NGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDE--DGQLDLEDILVAIDDKPKLVFL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 171 CTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:TIGR01141 150 CSPNNPTGNLFSRGDIEAVLERTpgDALVVVDEAYGEFSG-EPSTLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKTMkAKEFCE 328
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPGLEVYPSDANFVLIRFPGD-ADALFE 307
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 3122230 329 ELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYPGLLPNCLRITVGTREENDRFLAALREI 350
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
18-371 |
6.61e-145 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 413.76 E-value: 6.61e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 18 KPYVPGKSKEEiaraygikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGg 97
Cdd:COG0079 1 SPYVPGGPIEE--------PEDIIKLSSNENPYGPPPKVLEAIAAALDALNRYPDPDATALREALAEYYGVPPEQVLVG- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 98 DGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFLCTPNNPT 177
Cdd:COG0079 72 NGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLDE--DFSLDLDALLAAITERTDLVFLCNPNNPT 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 178 GNIIENRDVERVINET--DALVVIDHAYIEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMR 255
Cdd:COG0079 150 GTLLPREELEALLEALpaDGLVVVDEAYAEFVPEEDSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 256 VKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKdIKVYPSEANYLLVELKtMKAKEFCEELLKRGV 335
Cdd:COG0079 230 VRGPWNVNSLAQAAALAALEDRAYLEETRARLRAERERLAAALRALG-LTVYPSQANFVLVRVP-EDAAELFEALLERGI 307
|
330 340 350
....*....|....*....|....*....|....*.
gi 3122230 336 IVRDCTSFdGLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:COG0079 308 LVRDFSSF-GL-PDYLRITVGTPEENDRLLAALKEI 341
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
10-371 |
2.29e-98 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 296.99 E-value: 2.29e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 10 VRDVVKKLKPYVPGKSKEEIARAYGIKPEDIIKLGSNENPWGPSPKIKEKiLDEIDKIHQYPEPVNPILMKELSKFLNVD 89
Cdd:PLN03026 24 IRKHILQLAPYQPILPFEVLSAQLGRKPEDIVKLDANENPYGPPPEVLEA-LGNMKFPYVYPDPESRRLRAALAEDSGLE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 90 EENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIkyAKYDKEKDFKLNVESVLNNI-TDKTKVI 168
Cdd:PLN03026 103 SENILVGC-GADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEV--IKVPRTPDFSLDVPRIVEAVeTHKPKLL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 169 FLCTPNNPTGNIIENRDVERVInETDALVVIDHAYIEYAKKEyDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:PLN03026 180 FLTSPNNPDGSIISDDDLLKIL-ELPILVVLDEAYIEFSTQE-SRMKWVKKYDNLIVLRTFSKRAGLAGLRVGYGAFPLS 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKT-MKAKEFC 327
Cdd:PLN03026 258 IIEYLWRAKQPYNVSVAAEVAACAALSNPKYLEDVKNALVEERERLFGLLKEVPFLEPYPSDANFILCRVTSgRDAKKLK 337
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 3122230 328 EELLKRGVIVRDCTSFDglGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PLN03026 338 EDLAKMGVMVRHYNSKE--LKGYIRVSVGKPEHTDALMEALKQL 379
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
41-370 |
1.10e-85 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 263.43 E-value: 1.10e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 41 IKLGSNENPWGPSPKIKEKILDEIDK---IHQYPEPVNPILMKELSKFLN------VDEENIIVGgDGADEIIDTIFRTF 111
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRaglLGYYPDPGLPELREAIAEWLGrrggvdVPPEEIVVT-NGAQEALSLLLRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 112 VDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI- 190
Cdd:cd00609 80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAe 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 191 --NETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSL---T 263
Cdd:cd00609 160 laKKHGILIISDEAYAElvYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYTTsgpS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 264 RLSQVCAITALRDR-EFFERCVRDGIKSREMLYNGLKK-FKDIKVYPSEANYLLVELKTMKAKEFCEELL-KRGVIVRDC 340
Cdd:cd00609 240 TLSQAAAAAALDDGeEHLEELRERYRRRRDALLEALKElGPLVVVKPSGGFFLWLDLPEGDDEEFLERLLlEAGVVVRPG 319
|
330 340 350
....*....|....*....|....*....|.
gi 3122230 341 TSFDGLGDNYVRVSIGT-FEEVERFLKILEE 370
Cdd:cd00609 320 SAFGEGGEGFVRLSFATpEEELEEALERLAE 350
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
9-373 |
1.79e-71 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 227.16 E-value: 1.79e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 9 KVRDVVKKLKPYVPGKSkeeiaraygikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNV 88
Cdd:PRK03321 4 RLRPDLAGIPAYVPGKT-----------VPGAIKLSSNETPFGPLPSVRAAIARAAAGVNRYPDMGAVELRAALAEHLGV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 89 DEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKikYAKYDKEKDFKLNVESVLNNITDKTKVI 168
Cdd:PRK03321 73 PPEHVAVGC-GSVALCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGAT--PVQVPLTPDHTHDLDAMAAAITDRTRLI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 169 FLCTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKKEY--DWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGV 244
Cdd:PRK03321 150 FVCNPNNPTGTVVTPAELARFLDAVpaDVLVVLDEAYVEYVRDDDvpDGLELVRDHPNVVVLRTFSKAYGLAGLRVGYAV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 245 ANKKIIDYMMRVKPIFSLTRLSQVCAITALRDR-EFFERcVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKA 323
Cdd:PRK03321 230 GHPEVIAALRKVAVPFSVNSLAQAAAIASLAAEdELLER-VDAVVAERDRVRAALRA-AGWTVPPSQANFVWLPLGE-RT 306
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 3122230 324 KEFCEELLKRGVIVRdctSFDGLGdnyVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK03321 307 ADFAAAAAEAGVVVR---PFAGEG---VRVTIGAPEENDAFLRAARAWRA 350
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
10-371 |
8.91e-69 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 220.78 E-value: 8.91e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 10 VRDVVKKLKPYVPGKSKEEIARAYGikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVD 89
Cdd:PRK05166 10 ARAEVRPLPPYNAGLTIEEVRARYG--VPRIAKLGSNENPLGPSPAVRRAFADIAELLRLYPDPQGRALREAIAARTGVP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 90 EENIIVgGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKyaKYDKEKDFKLNVESVLNNITDKTKVIF 169
Cdd:PRK05166 88 ADRIIL-GNGSEDLIAVICRAVLRPGDRVVTLYPSFPLHEDYPTMMGARVE--RVTVTPDLGFDLDALCAAVARAPRMLM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 170 LCTPNNPTGNIIENRDVERVINETDA--LVVIDHAYIEYAKKEyDWTQKAPEYDNV----IVLRTFSKVFGLAGMRVGYG 243
Cdd:PRK05166 165 FSNPSNPVGSWLTADQLARVLDATPPetLIVVDEAYAEYAAGD-DYPSALTLLKARglpwIVLRTFSKAYGLAGLRVGYG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 244 -VANKKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmK 322
Cdd:PRK05166 244 lVSDPELVGLLDRVRTPFNVNGAAQAAALAALDDEEHLAKGVALALAERERLKKELAE-MGYRIAPSRANFLFFDARR-P 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 3122230 323 AKEFCEELLKRGVIVRDCTSfDGLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK05166 322 ASAVAEALLRQGVIVKPWKQ-PGF-ETFIRVSIGSPEENDHFVAALDKV 368
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
38-368 |
4.94e-68 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 217.94 E-value: 4.94e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 38 EDIIKLGSNENPWGPSPKIKEKILDEID--KIHQYPEP-VNPILMKELSKFLNVD-------EENIIVGGdGADEIIDTI 107
Cdd:pfam00155 1 TDKINLGSNEYLGDTLPAVAKAEKDALAggTRNLYGPTdGHPELREALAKFLGRSpvlkldrEAAVVFGS-GAGANIEAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 108 FRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNII---ENR 184
Cdd:pfam00155 80 IFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVAtleELE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 185 DVERVINETDALVVIDHAYIEYAKKEYDWTQKAP---EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFS 261
Cdd:pfam00155 160 KLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRAllaEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARPFY 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 262 LTRLSQVCAITALRDREFFERCV---RDGIKS-REMLYNGLKKfKDIKVYPSEAN-YLLVELKTMKAKEFCEELLKR-GV 335
Cdd:pfam00155 240 SSTHLQAAAAAALSDPLLVASELeemRQRIKErRDYLRDGLQA-AGLSVLPSQAGfFLLTGLDPETAKELAQVLLEEvGV 318
|
330 340 350
....*....|....*....|....*....|....*
gi 3122230 336 IVRDCTSFdgLGDNYVRVSI--GTFEEVERFLKIL 368
Cdd:pfam00155 319 YVTPGSSP--GVPGWLRITVagGTEEELEELLEAI 351
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
14-371 |
4.26e-60 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 198.43 E-value: 4.26e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 14 VKKLKPYVPGKSKEEiARAYGIKPEDIIKLGSNENPWGPSPKIKEKILDEIDK-IHQYPePVN--PILMKELSKF----- 85
Cdd:COG0436 7 LARLPPSPIREVSAL-AAELKAAGEDVIDLGIGEPDFPTPDHIREAAIEALDDgVTGYT-PSAgiPELREAIAAYykrry 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 -LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDK 164
Cdd:COG0436 85 gVDLDPDEILVTN-GAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDPEALEAAITPR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 165 TKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAGM 238
Cdd:COG0436 164 TKAIVLNSPNNPTGAVYSREELEALAelaREHDLLVISDEIYeeLVYDGAEHVSILSLPGlKDRTIVINSFSKSYAMTGW 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 239 RVGYGVANKKIIDYMMRVK--PIFSLTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFkDIKVYPSEAN-YL 314
Cdd:COG0436 244 RIGYAVGPPELIAALLKLQsnLTSCAPTPAQYAAAAALEgPQDYVEEMRAEYRRRRDLLVEGLNEI-GLSVVKPEGAfYL 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 315 LVELK--TMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVS----IGTFEE-VERFLKILEEI 371
Cdd:COG0436 323 FADVPelGLDSEEFAERLLeEAGVAVVPGSAFGPAGEGYVRISyatsEERLEEaLERLARFLERY 387
|
|
| L_thr_O3P_dcar |
TIGR01140 |
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ... |
28-368 |
5.71e-52 |
|
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 273466 Cd Length: 330 Bit Score: 175.84 E-value: 5.71e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 28 EIARAYGIKPEDIIKLGSNENPWG-PSPKIkekildEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGADEIIDT 106
Cdd:TIGR01140 7 RAAARYGIPPEDWLDLSTGINPLGpPVPPI------PLSAWARYPDPEYDELRAAAAAYYGLPAASVLPVN-GAQEAIYL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 107 IFRTFvdDGDEVIIPIPTFTQYRVSATIHNAKIKYAkYDKEKdfklnVESVLnnitDKTKVIFLCTPNNPTGNIIENRDV 186
Cdd:TIGR01140 80 LPRLL--APGRVLVLAPTYSEYARAWRAAGHEVVEL-PDLDR-----LPAAL----EEADLLVVCNPNNPTGRLIPPETL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 187 ERVIN---ETDALVVIDHAYIEYAkKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLT 263
Cdd:TIGR01140 148 LALAArlrARGGWLVVDEAFIDFT-PDASLAPQAARFPGLVVLRSLTKFFGLAGLRLGFVVAHPALIARLREALGPWTVN 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 264 RLSQVCAITALRDREFFERcVRDGIKS-REMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTS 342
Cdd:TIGR01140 227 GPALAAGRAALADTAWQAA-TRARLAAeRARLAALLARLGGLRVVGGTALFLLVRTP--DAAALHEALARRGILIRDFDN 303
|
330 340
....*....|....*....|....*.
gi 3122230 343 FDGLGDNYVRVSIGTFEEVERFLKIL 368
Cdd:TIGR01140 304 FPGLDPRYLRFALPTDEENDRLLEAL 329
|
|
| PRK03317 |
PRK03317 |
histidinol-phosphate aminotransferase; Provisional |
41-371 |
9.46e-52 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 235115 Cd Length: 368 Bit Score: 176.21 E-value: 9.46e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 41 IKLGSNENPWGPSPKIKEKILDEIDKI----HQYPEPVNPILMKELSKFLN------VDEENIIvGGDGADEIIDTIFRT 110
Cdd:PRK03317 29 VRLNTNENPYPPSPALVADIAEAVAEAaaglNRYPDRDAVALRADLAAYLTaqtgvgLTVENVW-AANGSNEILQQLLQA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 111 FVDDGDEVIIPIPTFTQYRVSAtiHNAKIKYAKYDKEKDFKLNVESVLNNITD-KTKVIFLCTPNNPTGNIIENRDVERV 189
Cdd:PRK03317 108 FGGPGRTALGFVPSYSMHPIIA--RGTHTEWVEGPRAADFTLDVDAAVAAIAEhRPDVVFLTSPNNPTGTALPLDDVEAI 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 190 INETDALVVIDHAYIEYAKkeyDWTQKA----PEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLTRL 265
Cdd:PRK03317 186 LDAAPGIVVVDEAYAEFRR---SGTPSAltllPEYPRLVVSRTMSKAFAFAGGRLGYLAAAPAVVDALRLVRLPYHLSAV 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 266 SQVCAITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKAKEFCEELLKRGVIVRDcTSFDG 345
Cdd:PRK03317 263 TQAAARAALRHADELLASVAALRAERDRVVAWLRE-LGLRVAPSDANFVLFGRFA-DRHAVWQGLLDRGVLIRD-VGIPG 339
|
330 340
....*....|....*....|....*.
gi 3122230 346 lgdnYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK03317 340 ----WLRVTIGTPEENDAFLAALAEV 361
|
|
| PRK02610 |
PRK02610 |
histidinol-phosphate transaminase; |
17-372 |
2.13e-44 |
|
histidinol-phosphate transaminase;
Pssm-ID: 235053 Cd Length: 374 Bit Score: 157.18 E-value: 2.13e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 17 LKPYVPGKSKEEIARAygiKPEDiiKLGSNENPWGPSPKIKEKILDEIDKI---HQYPEPVNPILMKELSKFLN------ 87
Cdd:PRK02610 12 LKAYHPHPSGDADDAV---IQLD--RLDTNEFPYDLPPDLKQKLAWLYQQGiesNRYPDGGHEALKQAIAEYVNesaags 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 88 --VDEENIIVGgDGADEIIDTIF-RTFVDDGDEVIIPIPTFTQYRVSA-TIHNAKIKYAKydKEKDFKLNVESVLNNITD 163
Cdd:PRK02610 87 sqITPANISVG-NGSDELIRSLLiATCLGGEGSILVAEPTFSMYGILAqTLGIPVVRVGR--DPETFEIDLAAAQSAIEQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 164 KT----KVIFLCTPNNPTGNIIENRDVERVIN-ETDALVVIDHAYIEYAKKEYdwTQKAPEYDNVIVLRTFSKVFGLAGM 238
Cdd:PRK02610 164 TQnppvRVVFVVHPNSPTGNPLTAAELEWLRSlPEDILVVIDEAYFEFSQTTL--VGELAQHPNWVILRTFSKAFRLAAH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 239 RVGYGVANKKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVEL 318
Cdd:PRK02610 242 RVGYAIGHPELIAVLEKVRLPYNLPSFSQLAAQLALEHRQELLAAIPEILQERDRLYQALQELPQLRVWPSAANFLYLRL 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 319 KTMKA-KEFCEELLKRGVIVRdCTSfDGLgdnyvRVSIGTFEEVERFLKILEEII 372
Cdd:PRK02610 322 SQDAAlAALHQALKAQGTLVR-HTG-GGL-----RITIGTPEENQRTLERLQAAL 369
|
|
| GntC_guanitoxin |
NF041364 |
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC; |
76-371 |
1.50e-43 |
|
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
Pssm-ID: 469255 Cd Length: 354 Bit Score: 154.42 E-value: 1.50e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 76 PILMKELSKFL------NVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKY-DKEK 148
Cdd:NF041364 40 LELREAIAALYkdgygiEVSPDQVLVT-TGASEALFLYFHALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLPLsPENQ 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYA-KKEYDWTQKAPEYDN 222
Cdd:NF041364 119 GFRPDLEALRSLITPRTRAIVINSPNNPTGAVMTEAELEAILEiasRHGLIVLADEHYrfLPYDdGKHVSPSLYPGLSER 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 223 VIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK--PIFSLTRLSQVCAITALRDREffERCVRDGIKS----REMLYN 296
Cdd:NF041364 199 VIALGSFSKTYGMTGLRVGWLIGPKELIGAILKFKdyTTHCAPSISQYAALEALEQGP--QERVKGWVREnvrrRDALVE 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230 297 GLKKFKDIKVYPSEANYLLVELK-TMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSIGtfEEVERFLKILEEI 371
Cdd:NF041364 277 RLERLIGWVCEPEGGFYAFPKLKdGLPSAAFAEELLeKAGVVVLPGSAFGRPGEGYFRIGFA--NSPTRLKEALERL 351
|
|
| PRK09105 |
PRK09105 |
pyridoxal phosphate-dependent aminotransferase; |
37-372 |
2.96e-40 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181651 Cd Length: 370 Bit Score: 145.96 E-value: 2.96e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 37 PEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGADEIIDTIFRTFVDDGD 116
Cdd:PRK09105 42 AEGAVFLNANECPLGPSPAARDAAARSAALSGRYDLELEDDLRTLFAAQEGLPADHVMAYA-GSSEPLNYAVLAFTSPTA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 117 EVIIPIPTFTQYRVSATIHNAKIkyAKYDKEKDFKLNVESVLNNITDkTKVIFLCTPNNPTGNIIENRDVERVINE--TD 194
Cdd:PRK09105 121 GLVTADPTYEAGWRAADAQGAPV--AKVPLRADGAHDVKAMLAADPN-AGLIYICNPNNPTGTVTPRADIEWLLANkpAG 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 195 ALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVAN----KKIIDYMMRVKPIFSLTrlsqvCA 270
Cdd:PRK09105 198 SVLLVDEAYIHFSD-APSVVDLVAQRKDLIVLRTFSKLYGMAGMRLGLAAARpdllAKLARFGHNPLPVPAAA-----AG 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 271 ITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKAKEFCEELLKRGVIV-RDCTSFdglgDN 349
Cdd:PRK09105 272 LASLRDPKLVPQRRAENAAVREDTIAWLKK-KGYKCTPSQANCFMVDVKR-PAKAVADAMAKQGVFIgRSWPIW----PN 345
|
330 340
....*....|....*....|...
gi 3122230 350 YVRVSIGTFEEVERFLKILEEII 372
Cdd:PRK09105 346 WVRVTVGSEEEMAAFRSAFAKVM 368
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
34-371 |
1.02e-38 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 140.25 E-value: 1.02e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 34 GIKPEDIIKLGSNENPWGPS--PKIKEKILDEIDKIHQYPEpvnpiLMKELSKFLNvdEENIIVGGdgADEIIDTIFRTF 111
Cdd:PRK08354 4 GIREEGLIDFSASVNPYPPEwlDEMFERAKEISGRYTYYEW-----LEEEFSKLFG--EPIVITAG--ITEALYLIGILA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 112 VDDGdEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKdfklnvesvLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN 191
Cdd:PRK08354 75 LRDR-KVIIPRHTYGEYERVARFFAARIIKGPNDPEK---------LEELVERNSVVFFCNPNNPDGKFYNFKELKPLLD 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 192 ---ETDALVVIDHAYIEYAKKeydwtQKAPEYDNVIVLRTFSKVFGLAGMRVGYgvankkIIDYmmrvKPIFSLTRLSQv 268
Cdd:PRK08354 145 aveDRNALLILDEAFIDFVKK-----PESPEGENIIKLRTFTKSYGLPGIRVGY------VKGF----EEAFRSVRMPW- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 269 cAITALrDREFFERCVRDGI----KSREMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTSFd 344
Cdd:PRK08354 209 -SIGST-GYAFLEFLIEDDFehlrKTMPLIWREKERFEKALYVKSDANFFIKDVG--DAEKFVEFLKRNGILVRDCTSF- 283
|
330 340
....*....|....*....|....*..
gi 3122230 345 GLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK08354 284 GL-PGYIRFSVRDREENEKLIRALREW 309
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
86-370 |
1.06e-38 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 142.19 E-value: 1.06e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKT 165
Cdd:PRK05764 87 LDYDPSQVIVTT-GAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGEENGFKLTVEQLEAAITPKT 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 166 KVIFLCTPNNPTGNIIENRDVE---RVINETDALVVIDHAY--IEYAKKEYDW-TQKAPE-YDNVIVLRTFSKVFGLAGM 238
Cdd:PRK05764 166 KALILNSPSNPTGAVYSPEELEaiaDVAVEHDIWVLSDEIYekLVYDGAEFTSiASLSPElRDRTITVNGFSKAYAMTGW 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 239 RVGYGVANKKIIDYMMRVKP-IFS-LTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSE-ANYL 314
Cdd:PRK05764 246 RLGYAAGPKELIKAMSKLQShSTSnPTSIAQYAAVAALNgPQDEVEEMRQAFEERRDLMVDGLNEIPGLECPKPEgAFYV 325
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3122230 315 ------LVELKTMKAKEFCEELLKR-GVIVRDCTSFdGLgDNYVRVSIGTFEE-----VERFLKILEE 370
Cdd:PRK05764 326 fpnvskLLGKSITDSLEFAEALLEEaGVAVVPGIAF-GA-PGYVRLSYATSLEdleegLERIERFLES 391
|
|
| PRK08153 |
PRK08153 |
pyridoxal phosphate-dependent aminotransferase; |
21-372 |
4.25e-37 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181255 Cd Length: 369 Bit Score: 137.44 E-value: 4.25e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 21 VPGKSKEEIARAYGIKPEdiIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGA 100
Cdd:PRK08153 17 VPFVGPETLERQRGRPFR--ARIGANESGFGPSPSVIAAMREAAAEIWKYGDPENHDLRHALAAHHGVAPENIMVGE-GI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 101 DEIIDTIFRTFVDDGDEVIIPI---PTFTqYRVSA---TIHnaKIKYAKyDKEkdfklNVESVLNNIT-DKTKVIFLCTP 173
Cdd:PRK08153 94 DGLLGLIVRLYVEPGDPVVTSLgayPTFN-YHVAGfggRLV--TVPYRD-DRE-----DLDALLDAARrENAPLVYLANP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 174 NNPTGNIIENRDVERVIN---ETdALVVIDHAYIEYAKKEydwtqKAPEYD----NVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PRK08153 165 DNPMGSWHPAADIVAFIEalpET-TLLVLDEAYCETAPAG-----AAPPIDtddpNVIRMRTFSKAYGLAGARVGYAIGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 247 KKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREML-----YNGLKKFkdikvyPSEANYLLVELKTM 321
Cdd:PRK08153 239 PGTIKAFDKVRNHFGMNRIAQAAALAALKDQAYLAEVVGKIAAARDRIaaiarANGLTPL------PSATNFVAIDCGRD 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 3122230 322 K--AKEFCEELLKRGVIVRdcTSFDGLGDNYVRVSIGTFEEVERFLKILEEII 372
Cdd:PRK08153 313 GafARAVLDGLIARDIFVR--MPGVAPLDRCIRVSCGPDEELDLFAEALPEAL 363
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
36-371 |
1.83e-36 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 136.16 E-value: 1.83e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 36 KPEDIIKLGSNENPWGPSPKIKEKILDEIDK--IHQYPEPVNPILMKELSKF------LNVDEENIIVGGdGADEIIDTI 107
Cdd:PRK08361 31 KMENVISLGIGEPDFDTPKNIKEAAKRALDEgwTHYTPNAGIPELREAIAEYykkfygVDVDVDNVIVTA-GAYEATYLA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 108 FRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---R 184
Cdd:PRK08361 110 FESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREENEFQPDPDELLELITKRTRMIVINYPNNPTGATLDKevaK 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 185 DVERVINETDALVVIDHAYIEY---AKKEYDWTQKAPeyDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--I 259
Cdd:PRK08361 190 AIADIAEDYNIYILSDEPYEHFlyeGAKHYPMIKYAP--DNTILANSFSKTFAMTGWRLGFVIAPEQVIKDMIKLHAyiI 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 260 FSLTRLSQVCAITALRDREFF---ERCVRDGIKSREMLYNGLKKFKDIKVY-PSEANYLLVELKT--MKAKEFCEELL-K 332
Cdd:PRK08361 268 GNVASFVQIAGIEALRSKESWkavEEMRKEYNERRKLVLKRLKEMPHIKVFePKGAFYVFANIDEtgMSSEDFAEWLLeK 347
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 3122230 333 RGVIVRDCTSFDGLGDNYVRVSIGT-----FEEVERFLKILEEI 371
Cdd:PRK08361 348 ARVVVIPGTAFGKAGEGYIRISYATskeklIEAMERMEKALEEL 391
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
33-372 |
1.99e-36 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 136.04 E-value: 1.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 33 YGIKPEDIIKLGSNENPWGPSPKIKEKILDEIDK--IHQYPEPVN-PILMKELSKFLNVDEENIIVGgDGADEIIDTIFR 109
Cdd:PRK06225 23 YVFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEgeYCKYPPPEGfPELRELILKDLGLDDDEALIT-AGATESLYLVMR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAK-YDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE- 187
Cdd:PRK06225 102 AFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPiYSEECNYKLTPELVKENMDENTRLIYLIDPLNPLGSSYTEEEIKe 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 188 --RVINETDALVVIDHAYIEYAKKEYDWTQKAPEydNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYM-MRVKPIFSLTR 264
Cdd:PRK06225 182 faEIARDNDAFLLHDCTYRDFAREHTLAAEYAPE--HTVTSYSFSKIFGMAGLRIGAVVATPDLIEVVkSIVINDLGTNV 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 265 LSQVCAITALRDR-EFFERCVRDGIKSREMLYNGLKKFKDIK--VYPSEANYLLVELKT--MKAKEFCEELLKRGVIVRD 339
Cdd:PRK06225 260 IAQEAAIAGLKVKdEWIDRIRRTTFKNQKLIKEAVDEIEGVFlpVYPSHGNMMVIDISEagIDPEDLVEYLLERKIFVRQ 339
|
330 340 350
....*....|....*....|....*....|....*.
gi 3122230 340 CTSFDGL-GDNYVRV--SIGTfEEVERFLKILEEII 372
Cdd:PRK06225 340 GTYTSKRfGDRYIRVsfSIPR-EQVEVFCEEFPDVV 374
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
110-354 |
7.86e-32 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 123.68 E-value: 7.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---RDV 186
Cdd:PRK06348 108 SILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDGFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKetlEEI 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 187 ERVINETDALVVIDHAYIEYAKKE--YDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--IFSL 262
Cdd:PRK06348 188 AKIAIEYDLFIISDEVYDGFSFYEdfVPMATLAGMPERTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEgiCFSA 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 263 TRLSQVCAITALRDREFFERCVRDGIKSR-EMLYNGLKKFKDIKVYPSEAN-YLLVELKT--MKAKEFCEELLKRG-VIV 337
Cdd:PRK06348 268 PTISQRAAIYALKHRDTIVPLIKEEFQKRlEYAYKRIESIPNLSLHPPKGSiYAFINIKKtgLSSVEFCEKLLKEAhVLV 347
|
250
....*....|....*..
gi 3122230 338 RDCTSFDGLGDNYVRVS 354
Cdd:PRK06348 348 IPGKAFGESGEGYIRLA 364
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
78-369 |
1.14e-30 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 120.22 E-value: 1.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 78 LMKELSKFLN------VDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFK 151
Cdd:PRK07682 62 LRQEIAKYLKkrfavsYDPNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLENEFK 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 152 LNVESVLNNITDKTKVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVL 226
Cdd:PRK07682 142 VQPAQIEAAITAKTKAILLCSPNNPTGAVLnksELEEIAVIVEKHDLIVLSDEIYAEltYDEAYTSFASIKGMRERTILI 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 227 RTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPiFSLT---RLSQVCAITALRD-REFFERcVRDGIKSREMLYngLKKFK 302
Cdd:PRK07682 222 SGFSKGFAMTGWRLGFIAAPVYFSEAMLKIHQ-YSMMcapTMAQFAALEALRAgNDDVIR-MRDSYRKRRNFF--VTSFN 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 303 DIKV---YPSEANYLLVELKT--MKAKEFCEELLK-RGVIVRDCTSFDGLGDNYVRVSIGT--------FEEVERFLKIL 368
Cdd:PRK07682 298 EIGLtchVPGGAFYAFPSISStgLSSEEFAEQLLLeEKVAVVPGSVFGESGEGFIRCSYATsleqlqeaMKRMKRFVENK 377
|
.
gi 3122230 369 E 369
Cdd:PRK07682 378 K 378
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
48-354 |
2.10e-29 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 116.83 E-value: 2.10e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 48 NPWGPSPK-----IKEKILDEIDKIHQY-PEPVNPILMKELSKFLN------VDEENII--VGGDGAdeiIDTIFRTFVD 113
Cdd:PRK06836 42 NPSVPPPAavkeaLRELAEEEDPGLHGYmPNAGYPEVREAIAESLNrrfgtpLTADHIVmtCGAAGA---LNVALKAILN 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 114 DGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDkEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI--- 190
Cdd:PRK06836 119 PGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTD-TDTFQPDLDALEAAITPKTKAVIINSPNNPTGVVYSEETLKALAall 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 191 ------NETDALVVIDHAYIEYAkkeYDWTQKA---PEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYmMRVKPIFS 261
Cdd:PRK06836 198 eekskeYGRPIYLISDEPYREIV---YDGAEVPyifKYYDNSIVVYSFSKSLSLPGERIGYIAVNPEMEDA-DDLVAALV 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 262 LT-R-LSQVCAiTALRDReFFERCVRDGI------KSREMLYNGLKKFKDIKVYPSEANYLLVELKTMKAKEFCEELLKR 333
Cdd:PRK06836 274 FAnRiLGFVNA-PALMQR-VVAKCLDATVdvsiykRNRDLLYDGLTELGFECVKPQGAFYLFPKSPEEDDVAFCEKAKKH 351
|
330 340
....*....|....*....|.
gi 3122230 334 GVIVRDCTSFDGLGdnYVRVS 354
Cdd:PRK06836 352 NLLLVPGSGFGCPG--YFRLS 370
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
9-371 |
1.13e-28 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 115.01 E-value: 1.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 9 KVRDVVKKLKPYVPG---KSKEEiARAYGikpEDIIKLGSNEnPWGPSPK-IKEKILDEIDKI--HQYPEPVN-PILMKE 81
Cdd:PRK09276 3 KLADRIKNLPPYLFAeidKKKAE-KIARG---VDVISLGIGD-PDLPTPDhIIEAMCKAVEDPenHQYPSYEGmLEFRKA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 82 LSKF------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVE 155
Cdd:PRK09276 78 VADWykrrfgVELDPETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLKEENGFLPDLD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 156 SVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEYdwtqKAPEYDNV-------IV 225
Cdd:PRK09276 158 AIPEDVAKKAKLMFINYPNNPTGAVADLEFFEEVVDfakKYDIIVCHDAAYSEIAYDGY----KPPSFLEVpgakdvgIE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 226 LRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-----IFSLTrlsQVCAITALR-DREFFERCVRDGIKSREMLYNGLK 299
Cdd:PRK09276 234 FHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKSnvdsgVFQAI---QEAGIAALNgPQEVVEELRKIYQERRDILVEGLR 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 300 KFkDIKVYPSEAN-YLLVEL-KTMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSIGTfeEVERFLKILEEI 371
Cdd:PRK09276 311 KL-GLEVEPPKATfYVWAPVpKGYTSAEFATLLLdKAGVVVTPGNGFGEYGEGYFRIALTV--PDERIEEAVERI 382
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
86-366 |
2.75e-28 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 113.67 E-value: 2.75e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKyDKEKDFKLNVESVLNNITDKT 165
Cdd:PRK07683 84 LHYSPESEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFID-TRSTGFRLTAEALENAITEKT 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 166 KVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK07683 163 RCVVLPYPSNPTGVTLskeELQDIADVLKDKNIFVLSDEIYSElvYEQPHTSIAHFPEMREKTIVINGLSKSHSMTGWRI 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 241 GYGVANKKIIDYMMRVKP--IFSLTRLSQVCAITALRDREFFERCVRDGIKSR-EMLYNGLKKFKDIKVYPSEANYLLVE 317
Cdd:PRK07683 243 GFLFAPSYLAKHILKVHQynVTCASSISQYAALEALTAGKDDAKMMRHQYKKRrDYVYNRLISMGLDVEKPTGAFYLFPS 322
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 318 LK--TMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVS----IGTFEE----VERFLK 366
Cdd:PRK07683 323 IGhfTMSSFDFALDLVEEaGLAVVPGSAFSEYGEGYVRLSyaysIETLKEgldrLEAFLQ 382
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
5-370 |
1.67e-26 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 109.17 E-value: 1.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 5 MIENKVRDV----VKKLKPYVpgkskeEIARAYGIKpedIIKLgsneNPWGPSPKIKEKILDEIDKIHqyPEPV------ 74
Cdd:PRK07568 2 KISKRVLNMpaspIRKLVPYA------DEAKKRGIK---VYHL----NIGQPDIKTPEVFFEAIKNYD--EEVLayshsq 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 75 -NPILMKELSKF-----LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEK 148
Cdd:PRK07568 67 gIPELREAFAKYykkwgIDVEPDEILITN-GGSEAILFAMMAICDPGDEILVPEPFYANYNGFATSAGVKIVPVTTKIEE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 149 DFKL-NVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAkkeYDwtqkAPEY---- 220
Cdd:PRK07568 146 GFHLpSKEEIEKLITPKTKAILISNPGNPTGVVYTKEELEMLAEiakKHDLFLISDEVYREFV---YD----GLKYtsal 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 221 ------DNVIVLRTFSKVFGLAGMRVGYGVA-NKKIIDYMMRvkpiFSLTRLS-----QVCAITALR-DREFFERCVRDG 287
Cdd:PRK07568 219 slegleDRVIIIDSVSKRYSACGARIGCLISkNKELIAAAMK----LCQARLSpptleQIGAAALLDtPESYFDEVREEY 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 288 IKSREMLYNGLKKFKDIKVY-PSEANYLLVELKTMKAKEFCEELLK------RGVIVRDCTSF---DGLGDNYVRVS-IG 356
Cdd:PRK07568 295 KKRRDILYEELNKIPGVVCEkPKGAFYIIAKLPVDDAEDFAKWLLTdfnyngETVMVAPASGFyatPGLGKNEIRIAyVL 374
|
410
....*....|....
gi 3122230 357 TFEEVERFLKILEE 370
Cdd:PRK07568 375 NEEDLKRAMEILKE 388
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
6-366 |
4.97e-23 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 99.11 E-value: 4.97e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 6 IENKVRDVVkklkpyVPGKSKEEiaraygiKPEDIIKLGSNEnP----WGPSPKIKEKILDEIDKIHQY-------PEPV 74
Cdd:PRK08363 11 VEYAIRDVV------LPARELEK-------KGIKVIRLNIGD-PvkfdFQPPEHMKEAYCRAIKEGHNYygpseglPELR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 75 NPILMKELSKF-LNVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLN 153
Cdd:PRK08363 77 EAIVKREKRKNgVDITPDDVRVT-AAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEYRTIEEEGWQPD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 154 VESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYDWTQKAPEyDNVIVLRT 228
Cdd:PRK08363 156 IDDIRKKITEKTKAIAVINPNNPTGALYEKKTLKEILDiagEHDLPVISDEIYdlMTYEGKHVSPGSLTKD-VPVIVMNG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 229 FSKVFGLAGMRVGY--GVANKKIIDYMMRVKPIFSLTRLS-----QVCAITALRD-REFFERCVRDGIKSREMLYNGLKK 300
Cdd:PRK08363 235 LSKVYFATGWRLGYiyFVDPEGKLAEVREAIDKLARIRLCpntpaQFAAIAGLTGpMDYLEEYMKKLKERRDYIYKRLNE 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 3122230 301 FKDIK-VYPSEANYL---LVELKTMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRV----SIGTFEE----VERFLK 366
Cdd:PRK08363 315 IPGIStTKPQGAFYIfprIEEGPWKDDKEFVLDVLhEAHVLFVHGSGFGEYGAGHFRLvflpPVEILEEamdrFEEFMR 393
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
87-370 |
1.30e-22 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 97.70 E-value: 1.30e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 87 NVDEENIIV--GGDGADEIIdtiFRTFVDDGDEVIIPIPTFTQ-YRVSATIhNAKIKYAKYDKEKDFKLNVESVLNNITD 163
Cdd:PRK07324 77 NVKPENILQtnGATGANFLV---LYALVEPGDHVISVYPTYQQlYDIPESL-GAEVDYWQLKEENGWLPDLDELRRLVRP 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 164 KTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEyDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK07324 153 NTKLICINNANNPTGALMDRAYLEEIVEiarSVDAYVLSDEVYRPLDEDG-STPSIADLYEKGISTNSMSKTYSLPGIRV 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 241 GYGVANKKII-------DYMMrvkpiFSLTRLSQVCAITALRDRE-FFERcvrdgikSREMLYNGLKKFKD-IK------ 305
Cdd:PRK07324 232 GWIAANEEVIdilrkyrDYTM-----ICAGVFDDMLASLALEHRDaILER-------NRKIVRTNLAILDEwVAkeprvs 299
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 3122230 306 -VYPSEANYLLVELKT-MKAKEFCEELLKR-GVIVRDCTSFDglGDNYVRVSIGTFEEV-ERFLKILEE 370
Cdd:PRK07324 300 yVKPKAVSTSFVKLDVdMPSEDFCLKLLKEtGVLLVPGNRFD--LEGHVRIGYCCDTETlKKGLKKLSE 366
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
86-363 |
6.00e-21 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 93.39 E-value: 6.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYdKEKDFKLNVESVLNNITDKT 165
Cdd:PLN00175 110 LVVDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTL-RPPDFAVPEDELKAAFTSKT 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 166 KVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAkKEYDWTQKAP---EYDNVIVLRTFSKVFGLAGMR 239
Cdd:PLN00175 189 RAILINTPHNPTGKMFTREELELIASlckENDVLAFTDEVYDKLA-FEGDHISMASlpgMYERTVTMNSLGKTFSLTGWK 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 240 VGYGVANKKIIdYMMRVKP---IFSLTRLSQVCAITALRDRE-FFERCVRDGIKSREMLYNGLKKFkDIKVYPSEANYLL 315
Cdd:PLN00175 268 IGWAIAPPHLT-WGVRQAHsflTFATATPMQWAAVAALRAPEsYYEELKRDYSAKKDILVEGLKEV-GFKVYPSSGTYFV 345
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 3122230 316 VELKTMKAKE----FCEELLKRGVIVRDCTSFDGL----GDNYVRVSIGTFEEVER 363
Cdd:PLN00175 346 MVDHTPFGFEndiaFCEYLIEEVGVAAIPPSVFYLnpedGKNLVRFAFCKDEETLR 401
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
14-355 |
3.25e-20 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 90.93 E-value: 3.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 14 VKKLKPYV---PGKSKEEiARAYGikpEDIIKLGSNeNPWGPSPK-IKEKILDEIDK--IHQYPEPVN-PILMKELSKF- 85
Cdd:PRK08175 6 IDRLPPYVfniTAELKMA-ARRRG---EDIIDFSMG-NPDGPTPPhIVEKLCEVAQRpdTHGYSTSRGiPRLRRAISRWy 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 -----LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNN 160
Cdd:PRK08175 81 qdrydVDIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 161 ITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEYdwtqKAPEY-------DNVIVLRTFS 230
Cdd:PRK08175 161 SYPKPKMMILGFPSNPTAQCVELEFFEKVVAlakRYDVLVVHDLAYADIVYDGW----KAPSImqvpgakDVAVEFFTLS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 231 KVFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALrdrEFFERCVRDGI----KSREMLYNG 297
Cdd:PRK08175 237 KSYNMAGWRIGFMVGNPELVSALARIKsyhdygtftPL-------QVAAIAAL---EGDQQCVRDIAeqykRRRDVLVKG 306
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230 298 LKKFKDIKVYPSEANYLLVEL----KTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSI 355
Cdd:PRK08175 307 LHEAGWMVEMPKASMYVWAKIpepyAAMGSLEFAKKLLNEaKVCVSPGIGFGDYGDTHVRFAL 369
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
41-372 |
7.06e-20 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 90.13 E-value: 7.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 41 IKLGSNENPWGPSPKIKEKILDEID--KIHQYpEPVNPI------LMKELSKF--LNVDEENIIVGGDGADEIIDTIFRT 110
Cdd:PRK05957 30 ISLGQGVVSYPPPPEAIEALNNFLAnpENHKY-QAVQGIpplleaITQKLQQDngIELNNEQAIVVTAGSNMAFMNAILA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---RDVE 187
Cdd:PRK05957 109 ITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDD--NYQLQPEAIEQAITPKTRAIVTISPNNPTGVVYPEallRAVN 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 188 RVINETDALVVIDHAYiEYAKkeYD----WTQKA-PEYDN-VIVLRTFSKVFGLAGMRVGYGV-------ANKKIIDYMM 254
Cdd:PRK05957 187 QICAEHGIYHISDEAY-EYFT--YDgvkhFSPGSiPGSGNhTISLYSLSKAYGFASWRIGYMVipihlleAIKKIQDTIL 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 255 RVKPIFsltrlSQVCAITALRD-REFFERCVRDGIKSREMLYNGLKKFKDIK--VYPSEANYLLVELKT-MKAKEFCEEL 330
Cdd:PRK05957 264 ICPPVV-----SQYAALGALQVgKSYCQQHLPEIAQVRQILLKSLGQLQDRCtlHPANGAFYCFLKVNTdLNDFELVKQL 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 3122230 331 LKR-GVIVRDCTSFdGLGDN-YVRVSIGTFEE------VERFLKILEEII 372
Cdd:PRK05957 339 IREyRVAVIPGTTF-GMKNGcYLRIAYGALQKatakegIERLVQGLKTIV 387
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
111-363 |
1.75e-19 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 89.09 E-value: 1.75e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI 190
Cdd:PRK07681 113 YANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVI 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 191 ---NETDALVVIDHAYIEYAkkeYDwTQKAPEYDNV-------IVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK--- 257
Cdd:PRK07681 193 afaKKHNIIVVHDFAYAEFY---FD-GNKPISFLSVpgakevgVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKsnt 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 258 ------PIfsltrlsQVCAITALR--------DREFFErcvrdgiKSREMLYNGLKKFKDIKVYPSEANYLLVEL-KTMK 322
Cdd:PRK07681 269 dygvflPI-------QKAACAALRngaafcekNRGIYQ-------ERRDTLVDGFRTFGWNVDKPAGSMFVWAEIpKGWT 334
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 3122230 323 AKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSIGTFEEVER 363
Cdd:PRK07681 335 SLSFAYALMDRaNVVVTPGHAFGPHGEGFVRIALVQDEEVLQ 376
|
|
| PRK07908 |
PRK07908 |
threonine-phosphate decarboxylase; |
173-373 |
5.31e-19 |
|
threonine-phosphate decarboxylase;
Pssm-ID: 236128 Cd Length: 349 Bit Score: 86.98 E-value: 5.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 173 PNNPTGnIIENRDVERVINETDALVVIDHAYIeyakkeyDWTQKAPE------YDNVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PRK07908 148 PTNPTS-VLHPAEQLLALRRPGRILVVDEAFA-------DAVPGEPEslagddLPGVLVLRSLTKTWSLAGLRVGYALGA 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 247 KKIIDYMMRVKPIFS-----LTRLSQVCAITALRD-REFFERCVRDgiksREMLYNGLKKFKDIKVYPSEANYLLVELKt 320
Cdd:PRK07908 220 PDVLARLTRGRAHWPvgtlqLEAIAACCAPRAVAEaAADAARLAAD----RAEMVAGLRAVGARVVDPAAAPFVLVRVP- 294
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 3122230 321 mKAKEFCEELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK07908 295 -DAELLRKRLRERGIAVRRGDTFPGLDPDYLRLAVRPRAEVPVLVQALAEILK 346
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
69-373 |
2.79e-18 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 86.04 E-value: 2.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 69 QYPEPV-NPILMKELSKFLN-----VDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYA 142
Cdd:COG1167 143 GYGDPQgLPELREAIARYLArrgvpASPDQILITS-GAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPV 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 143 KYDKEKdfkLNVESVLNNITD-KTKVIFLcTPN--NPTGNI--IENRdvERVIN---ETDALVVIDHAYIEYAkkeYDwt 214
Cdd:COG1167 222 PVDEDG---LDLDALEAALRRhRPRAVYV-TPShqNPTGATmsLERR--RALLElarRHGVPIIEDDYDSELR---YD-- 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 215 QKAP-------EYDNVIVLRTFSKVFGlAGMRVGYGVANKKIIDYMMRVKPIFSLT--RLSQvcAITA--LRDREfFERC 283
Cdd:COG1167 291 GRPPpplaaldAPGRVIYIGSFSKTLA-PGLRLGYLVAPGRLIERLARLKRATDLGtsPLTQ--LALAefLESGH-YDRH 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 284 VRdGIKS-----REMLYNGLKKF--KDIKVYPSEA-NYLLVEL-KTMKAKEFCEELLKRGVIVRDCTSF--DGLGDNYVR 352
Cdd:COG1167 367 LR-RLRReyrarRDLLLAALARHlpDGLRVTGPPGgLHLWLELpEGVDAEALAAAALARGILVAPGSAFsaDGPPRNGLR 445
|
330 340
....*....|....*....|...
gi 3122230 353 VSIGTF--EEVERFLKILEEIIS 373
Cdd:COG1167 446 LGFGAPseEELEEALRRLAELLR 468
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
3-355 |
3.50e-17 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 82.07 E-value: 3.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 3 DWMienKVRDVVKKLKPYVPGKSKEEIARA--YGIkpeDIIKLGSNeNPWGPSPK-IKEKILDEID--KIHQYP------ 71
Cdd:PRK05942 4 DWI---TPADRLQALPPYVFARLDELKARAreQGL---DLIDLGMG-NPDGAAPQpVIEAAIAALAdpQNHGYPpfegta 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 72 ---EPVNPILMKELSKFLNVDEENIIVggDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEK 148
Cdd:PRK05942 77 sfrQAITDWYHRRYGVELDPDSEALPL--LGSKEGLTHLALAYVNPGDVVLVPSPAYPAHFRGPLIAGAQIYPIILKPEN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAKKEYDWTQ--KAPEYDNV 223
Cdd:PRK05942 155 DWLIDLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVafaRKYEIMLVHDLCYAELAFDGYQPTSllEIPGAKDI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 224 IV-LRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-----IFSLTrlsQVCAITALRDREFFERCVRDGIKS-REMLYN 296
Cdd:PRK05942 235 GVeFHTLSKTYNMAGWRVGFVVGNRHIIQGLRTLKTnldygIFSAL---QKAAETALQLPDSYLQQVQERYRTrRDFLIQ 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 3122230 297 GLKKFkDIKVYPSEAN-YLLVELKT-MKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSI 355
Cdd:PRK05942 312 GLGEL-GWNIPPTKATmYLWVPCPVgMGSTDFALNVLqKTGVVVTPGNAFGEGGEGYVRISL 372
|
|
| PRK06425 |
PRK06425 |
histidinol-phosphate aminotransferase; Validated |
32-373 |
1.19e-16 |
|
histidinol-phosphate aminotransferase; Validated
Pssm-ID: 102370 Cd Length: 332 Bit Score: 79.90 E-value: 1.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 32 AYGIKPEDIIKLGSNENPWgpspkikekilDEIDKIHQYPEpVNPILMKELSKFLNVDEENIIVGGDGADEIIDTIFrTF 111
Cdd:PRK06425 10 EASSKYGRIIDFSANINDF-----------MDIGDISIYPE-ISYTDIEDQIKIYTQGLKIKVLIGPGLTHFIYRLL-SY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 112 VDDGDEVIIpIPTFTQYRVSATIHNAKIKYAKYDKEKdfklNVESVLNNItdKTKVIFLCTPNNPTGNIIENRDVERVIN 191
Cdd:PRK06425 77 INVGNIIIV-EPNFNEYKGYAFTHGIRISALPFNLIN----NNPEILNNY--NFDLIFIVSPDNPLGNLISRDSLLTISE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 192 ETD---ALVVIDHAYIEYAKKEYDWT-QKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSltrlsq 267
Cdd:PRK06425 150 ICRkkgALLFIDEAFIDFVPNRAEEDvLLNRSYGNVIIGRSLTKILGIPSLRIGYIATDDYNMKISRKITEPWS------ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 268 VC--AITALRD---REFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTS 342
Cdd:PRK06425 224 VCdpAIDFIRSidlDYVAKHSLDIMENERSYLINNLEAMGFRAAGDPSANFITFMIP--DAHDFYSYLLKNGILVRLLDD 301
|
330 340 350
....*....|....*....|....*....|.
gi 3122230 343 FDGLGDNYVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK06425 302 YECLGEQYIRIAIRRRSFNIKLVNALRNFLN 332
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
93-361 |
8.47e-16 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 78.24 E-value: 8.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 93 IIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCT 172
Cdd:PRK06107 96 ITVGG-GAKQAIFLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPEEQGFKLTPEALEAAITPRTRWLILNA 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 173 PNNPTGNII---ENRDVERVINE-TDALVVIDHAYIEYAKKEYDWT---QKAPEY-DNVIVLRTFSKVFGLAGMRVGYGV 244
Cdd:PRK06107 175 PSNPTGAVYsraELRALADVLLRhPHVLVLTDDIYDHIRFDDEPTPhllAAAPELrDRVLVTNGVSKTYAMTGWRIGYAA 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 245 ANKKIIDYMMRVKPIFS--LTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFKDIK-VYPSEANYLLV---- 316
Cdd:PRK06107 255 GPADLIAAINKLQSQSSscPSSISQAAAAAALNgDQSFVTESVAVYKQRRDYALALLNAIPGLScLVPDGAFYLYVncag 334
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 3122230 317 -------ELKTMKA-KEFCEELLKR-GVIVRDCTSFdGLGDnYVRVSIGTFEEV 361
Cdd:PRK06107 335 ligkttpEGKVLETdQDVVLYLLDSaGVAVVQGTAY-GLSP-YFRLSIATSLET 386
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
8-369 |
8.80e-16 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 78.15 E-value: 8.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 8 NKVRDVVKKLKPYvPGKSKEeiaraygikpedIIKLGSNENPWGPS----PKIKEKILDEIDKiHQY----PEPVNPILM 79
Cdd:TIGR01265 14 NPIRAIVDNLKVK-PNPEKP------------VIPLSHGDPSVFGNlrtdPEAEEAVKDALRS-GKFngyaPSVGALAAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 80 KELSKFLNVDEENIIVGGD-----GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNV 154
Cdd:TIGR01265 80 EAVAEYLSSDLPGKLTADDvvltsGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSGLEVRLYDLLPEKDWEIDL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 155 ESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY--IEYAKKEY----DWTQKAPeydnVIV 225
Cdd:TIGR01265 160 DGLESLADEKTVAIVVINPSNPCGSVFSRDHLQKIAevaEKLGIPIIADEIYghMVFGDAPFipmaSFASIVP----VLS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 226 LRTFSKVFGLAGMRVGY-------GVANKKIIDymmrvkpifSLTRLSQV----CAIT--ALRD------REFFERcVRD 286
Cdd:TIGR01265 236 LGGISKRWVVPGWRLGWiiihdphGIFRDTVLQ---------GLKNLLQRilgpATIVqgALPDilentpQEFFDG-KIS 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 287 GIKSREML-YNGLKKFKDIK-VYPSEANYLLVELKTMKAKE------FCEELLK-RGVIVRDCTSFdGLgDNYVRVSIGT 357
Cdd:TIGR01265 306 VLKSNAELcYEELKDIPGLVcPKPEGAMYLMVKLELELFPEikddvdFCEKLAReESVICLPGSAF-GL-PNWVRITITV 383
|
410
....*....|....
gi 3122230 358 FEEV--ERFLKILE 369
Cdd:TIGR01265 384 PESMleEACSRIKE 397
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
88-314 |
1.78e-15 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 76.91 E-value: 1.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 88 VDEENIIVGGDGADEIIDTIfRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKD-FKLNVESVLNNITDKTK 166
Cdd:PRK06108 82 TPPERIAVTSSGVQALMLAA-QALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGGGgWTLDLDRLLAAITPRTR 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 167 VIFLCTPNNPTGNIIeNRDVERVI----NETDALVVIDHAYIEYAkkeYDWTQKAPEY-------DNVIVLRTFSKVFGL 235
Cdd:PRK06108 161 ALFINSPNNPTGWTA-SRDDLRAIlahcRRHGLWIVADEVYERLY---YAPGGRAPSFldiaepdDRIIFVNSFSKNWAM 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 236 AGMRVGYGVAN-------KKIIDYMMRVKPIFsltrlSQVCAITALRDRE-FFERCVRDGIKSREMLYNGLKKFKDIKVY 307
Cdd:PRK06108 237 TGWRLGWLVAPpalgqvlEKLIEYNTSCVAQF-----VQRAAVAALDEGEdFVAELVARLRRSRDHLVDALRALPGVEVA 311
|
....*...
gi 3122230 308 PSE-ANYL 314
Cdd:PRK06108 312 KPDgAMYA 319
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
111-360 |
9.74e-15 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 74.96 E-value: 9.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI 190
Cdd:PRK08068 114 LMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAENNFLPDYTKIPEEVAEKAKLMYLNYPNNPTGAVATKAFFEETV 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 191 ---NETDALVVIDHAY--IEY-AKKEYDWTQkAPEYDNV-IVLRTFSKVFGLAGMRVGYGVANKKII-------DYMMrv 256
Cdd:PRK08068 194 afaKKHNIGVVHDFAYgaIGFdGQKPVSFLQ-TPGAKDVgIELYTLSKTFNMAGWRVAFAVGNESVIeainllqDHLF-- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 257 kpiFSLTRLSQVCAITALRDReffERCVRDGI----KSREMLYNGLKKFK-DIKVyPSEANYLLVEL-KTMKAKEFCEEL 330
Cdd:PRK08068 271 ---VSLFGAIQDAAIEALLSD---QSCVAELVaryeSRRNAFISACREIGwEVDA-PKGSFFAWMPVpKGYTSEQFADLL 343
|
250 260 270
....*....|....*....|....*....|.
gi 3122230 331 LKR-GVIVRDCTSFDGLGDNYVRVSIGTFEE 360
Cdd:PRK08068 344 LEKaHVAVAPGNGFGEHGEGYVRVGLLTDEE 374
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
38-354 |
1.76e-14 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 73.99 E-value: 1.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 38 EDIIKLGSNENPWGPSPKIKEKILDEID--KIHQYPEPVNPILMKELSKF------LNVDEENIIVGGDGADEIIDTIFR 109
Cdd:PRK07309 30 PGILKLTLGEPDFTTPDHVKEAAKRAIDanQSHYTGMAGLLELRQAAADFvkekynLDYAPENEILVTIGATEALSASLT 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKyDKEKDFKLNVESVLNNIT---DKTKVIFLCTPNNPTGnIIENRD- 185
Cdd:PRK07309 110 AILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEID-TTENDFVLTPEMLEKAILeqgDKLKAVILNYPANPTG-VTYSREq 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 186 ---VERVINETDALVVIDHAYIEYAKKEYDWTQKApEY--DNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-- 258
Cdd:PRK07309 188 ikaLADVLKKYDIFVISDEVYSELTYTGEPHVSIA-EYlpDQTILINGLSKSHAMTGWRIGLIFAPAEFTAQLIKSHQyl 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 259 IFSLTRLSQVCAITAL---RDREFFERcvRDGIKSREMLYNGLKK--FKDIKvyPSEANYLLVELKT---MKAKEFCEEL 330
Cdd:PRK07309 267 VTAATTMAQFAAVEALtngKDDALPMK--KEYIKRRDYIIEKMTDlgFKIIK--PDGAFYIFAKIPAgynQDSFKFLQDF 342
|
330 340
....*....|....*....|....*
gi 3122230 331 L-KRGVIVRDCTSFDGLGDNYVRVS 354
Cdd:PRK07309 343 ArKKAVAFIPGAAFGPYGEGYVRLS 367
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
12-370 |
5.12e-14 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 72.81 E-value: 5.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 12 DVVKKLKPYVPGKSkEEIARAYGIKPEDIIKLgSNENPWGPSPK-IKEKILDEI--DKIHQYPepvnpiLMKELSKF--- 85
Cdd:PRK08636 8 NKIKRLPKYVFAEV-NELKMAARRAGEDIIDF-SMGNPDGPTPQhIIDKLCESAqkPKTHGYS------VSKGIYKLrla 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 86 ----------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTF---TQYRVSA--TIHNAKIKY-AKYD-KEK 148
Cdd:PRK08636 80 icnwykrkynVDLDPETEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYpihSQAFILAggNVHKMPLEYnEDFElDED 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAKKEYdwtqKAPEY----- 220
Cdd:PRK08636 160 QFFENLEKALRESSPKPKYVVVNFPHNPTTATVEKSFYERLValaKKERFYIISDIAYADITFDGY----KTPSIleveg 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 221 --DNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDReffERCVRDGI- 288
Cdd:PRK08636 236 akDVAVESYTLSKSYNMAGWRVGFVVGNKKLVGALKKIKswldygmftPI-------QVAATIALDGD---QSCVEEIRe 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 289 ---KSREMLyngLKKFKDIK---VYPSEANYLLVEL----KTMKAKEFCEELLKRG-VIVRDCTSFDGLGDNYVRVSIGT 357
Cdd:PRK08636 306 tyrKRRDVL---IESFANAGwelQKPRASMFVWAKIpepaRHLGSLEFSKQLLTEAkVAVSPGIGFGEYGDEYVRIALIE 382
|
410 420
....*....|....*....|.
gi 3122230 358 FEE--------VERFLKILEE 370
Cdd:PRK08636 383 NENrirqaarnIKKFLKELEG 403
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
27-371 |
6.43e-14 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 72.38 E-value: 6.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 27 EEIARA--YGIK--PE-DIIKLGSNENPWGPSPKIKEKILDEIDK----------IHQYPEPVnPILMKELSKFLNVDEE 91
Cdd:PRK06290 28 EKIKRAkrAAKEkhPDmELIDMGVGEPDEMADESVVEVLCEEAKKpenrgyadngIQEFKEAA-ARYMEKVFGVKDIDPV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 92 NIIVGGDGADEIIDTIFRTFVDDGDEVIIPIP------TFTQYrVSATIHNAKIKyakydKEKDFKLNVESVLNNITDKT 165
Cdd:PRK06290 107 TEVIHSIGSKPALAMLPSCFINPGDVTLMTVPgypvtgTHTKY-YGGEVYNLPLL-----EENNFLPDLDSIPKDIKEKA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 166 KVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK06290 181 KLLYLNYPNNPTGAVATKEFYEEVVDfakENNIIVVQDAAYAAltFDGKPLSFLSVPGAKEVGVEIHSLSKAYNMTGWRL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 241 GYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDREFFERcVRDGIKSR-EMLYNGLKK--FKDIKvyP 308
Cdd:PRK06290 261 AFVVGNELIVKAFATVKdnndsgqfiAI-------QKAGIYALDHPEITEK-IREKYSRRlDKLVKILNEvgFKAEM--P 330
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230 309 SEANYLLVEL-KTMK-------AKEFCEELLKRGVIVrdCTSFDGLGdNYVRVSIgTFE--EVERFLKILEEI 371
Cdd:PRK06290 331 GGTFYLYVKApKGTKsgikfenAEEFSQYLIKEKLIS--TVPWDDAG-HFLRFSV-TFEakDEEEEDRILEEI 399
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
87-318 |
1.99e-13 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 71.31 E-value: 1.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 87 NVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTK 166
Cdd:PRK13355 205 NVDVDDIYTG-NGVSELINLSMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHYRCDEQSEWYPDIDDIRSKITSRTK 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 167 VIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYdwTQKAPEYDNVIVLrTF---SKVFGLAGM 238
Cdd:PRK13355 284 AIVIINPNNPTGALYPREVLQQIVDiarEHQLIIFSDEIYdrLVMDGLEH--TSIASLAPDLFCV-TFsglSKSHMIAGY 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 239 RVGYGV--ANKKII-DYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGI-------KSREMLYNGLKKFKDIK-VY 307
Cdd:PRK13355 361 RIGWMIlsGNKRIAkDYIEGLNMLANMRLCSNVPAQSIVQTALGGHQSVKDYLvpggrvyEQRELVYNALNAIPGISaVK 440
|
250
....*....|.
gi 3122230 308 PSEANYLLVEL 318
Cdd:PRK13355 441 PKAAFYIFPKI 451
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
112-340 |
2.10e-12 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 67.89 E-value: 2.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 112 VDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEkDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVER--- 188
Cdd:PRK12414 111 VHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPE-DFRVNWDEVAAAITPRTRMIIVNTPHNPSATVFSAADLARlaq 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 189 VINETDALVVIDHAY--IEYAKKEYDWTQKAPEY--DNVIVlRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--IFSL 262
Cdd:PRK12414 190 LTRNTDIVILSDEVYehVVFDGARHHSMARHRELaeRSVIV-SSFGKSYHVTGWRVGYCLAPAELMDEIRKVHQfmVFSA 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 263 TRLSQVCAITALRDRE-------FFERcvrdgikSREMLYNGLKKFKdIKVYPSEANYLLVELKTMKAKEFCEELLKRgv 335
Cdd:PRK12414 269 DTPMQHAFAEALAEPAsylglgaFYQR-------KRDLLARELAGSR-FELLPSEGSFFMLARFRHFSDESDSDFVLR-- 338
|
....*
gi 3122230 336 IVRDC 340
Cdd:PRK12414 339 LIRDA 343
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
91-331 |
2.81e-12 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 67.50 E-value: 2.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 91 ENIIVGGDGADEIIdTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFL 170
Cdd:PTZ00433 105 DNVVLCSGVSHAIL-MALTALCDEGDNILVPAPGFPHYETVCKAYGIEMRFYNCRPEKDWEADLDEIRRLVDDRTKALIM 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 171 CTPNNPTGNIIENRDVERVINETDAL---VVIDHAYIEYAKKEYDWTQKAPEYDNV--IVLRTFSKVFGLAGMRVGYGVa 245
Cdd:PTZ00433 184 TNPSNPCGSNFSRKHVEDIIRLCEELrlpLISDEIYAGMVFNGATFTSVADFDTTVprVILGGTAKNLVVPGWRLGWLL- 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 246 nkkIIDyMMRVKPIF--SLTRLSQV----CAI------TALRD--REFFERCVRDGIKSREMLYNGLKKFKDIK-VYPSE 310
Cdd:PTZ00433 263 ---LVD-PHGNGGDFldGMKRLGMLvcgpCSVvqaalgEALLNtpQEHLEQIVAKLEEGAMVLYNHIGECIGLSpTMPRG 338
|
250 260
....*....|....*....|....*..
gi 3122230 311 ANYLLVELKTMKAK------EFCEELL 331
Cdd:PTZ00433 339 SMFLMSRLDLEKFRdiksdvEFYEKLL 365
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
99-245 |
4.73e-11 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 63.40 E-value: 4.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKeKDFKLNVESVLNNITDKTKVIFLCTPNNPTG 178
Cdd:PRK09082 99 GATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQP-PDFRVDWQRFAAAISPRTRLIILNTPHNPSG 177
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230 179 NIIENRDVER---VINETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK09082 178 TVWSAADMRAlwqLIAGTDIYVLSDEVYehIVFDGAGHASVLRHPElRERAFVVSSFGKTYHVTGWKVGYCVA 250
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
24-368 |
7.76e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 62.77 E-value: 7.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 24 KSKEEIARAygikPEDIIKLGSNENPWGPSPKIKEKILDEI-DKIHQYPEPVN-PILMKELSKF------LNVDEENIIV 95
Cdd:PRK07337 20 KEAQALERA----GRDIIHMGIGEPDFTAPEPVVEAAARALrRGVTQYTSALGlAPLREAIAAWyarrfgLDVAPERIVV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 96 GGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYR--VSATihNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTP 173
Cdd:PRK07337 96 TA-GASAALLLACLALVERGDEVLMPDPSYPCNRhfVAAA--EGRPVLVPSGPAERFQLTAADVEAAWGERTRGVLLASP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 174 NNPTGNIIENRDVERVINETDA---LVVIDHAYIEYAkkeYDwtqKAPEY-----DNVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK07337 173 SNPTGTSIAPDELRRIVEAVRArggFTIVDEIYQGLS---YD---AAPVSalslgDDVITINSFSKYFNMTGWRLGWLVV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 246 NKKIIdymmrvkPIFSltRLSQ---VCAIT-----AL-------------RDREFFERcvRDGI-KSREMLynGLKkfkd 303
Cdd:PRK07337 247 PEALV-------GTFE--KLAQnlfICASAlaqhaALacfepdtlaiyerRRAEFKRR--RDFIvPALESL--GFK---- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 304 IKVYPSEANYLLVELKTMKAK------EFCEELLKR-GVIV---RDCTSFDGLgdNYVRVSIGTF-----EEVERFLKIL 368
Cdd:PRK07337 310 VPVMPDGAFYVYADCRGVAHPaagdsaALTQAMLHDaGVVLvpgRDFGPHAPR--DYIRLSYATSmsrleEAVARLGKLF 387
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
85-244 |
1.14e-10 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 62.52 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 85 FLNVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDK 164
Cdd:PRK09265 90 IPDVDVDDIYIG-NGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVHYLCDEEAGWFPDLDDIRSKITPR 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 165 TKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYdwTQKAPEYDNVIVLrTF---SKVFGLA 236
Cdd:PRK09265 169 TKAIVIINPNNPTGAVYSKELLEEIVEiarQHNLIIFADEIYdkILYDGAVH--ISIASLAPDLLCV-TFnglSKAYRVA 245
|
....*...
gi 3122230 237 GMRVGYGV 244
Cdd:PRK09265 246 GFRVGWMV 253
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
160-372 |
1.17e-10 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 62.56 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 160 NITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY------IEYAKKEYDWTqkapeyDNVIVLRTFS 230
Cdd:PRK09440 175 HIDEDTGAICVSRPTNPTGNVLTDEELEKLDalaRQHNIPLLIDNAYgppfpgIIFSEATPLWN------PNIILCMSLS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 231 KVfGLAGMRVGYGVANKKIIDYMMRVKPIFSL--TRLSQVCAITALRDREFFERCVRDgIKS-----REMLYNGLKK-FK 302
Cdd:PRK09440 249 KL-GLPGVRCGIVIADEEIIEALSNMNGIISLapGRLGPAIAAEMIESGDLLRLSETV-IRPfyrqkVQLAIALLRRyLP 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 303 DIKVY---PSEANYLLVELK--TMKAKEFCEELLKRGV-IVRDCTSFDGLGDNY------VRVSI-GTFEEVERFLKILE 369
Cdd:PRK09440 327 DEPCLihkPEGAIFLWLWFKdlPITTEELYQRLKARGVlVVPGHYFFPGLDEDWphahqcIRMNYvQDDEEIEKGIAILA 406
|
...
gi 3122230 370 EII 372
Cdd:PRK09440 407 EEV 409
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
99-335 |
2.23e-10 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 61.59 E-value: 2.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQY----------RVSATIHNAkikyakydkEKDFKLNVESVLNNITDKTKVI 168
Cdd:PRK07777 93 GATEAIAAAVLGLVEPGDEVLLIEPYYDSYaaviamagahRVPVPLVPD---------GRGFALDLDALRAAVTPRTRAL 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 169 FLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIEYAkkeYDWTQKAP------EYDNVIVLRTFSKVFGLAGMR 239
Cdd:PRK07777 164 IVNSPHNPTGTVLtaaELAAIAELAVEHDLLVITDEVYEHLV---FDGARHLPlatlpgMRERTVTISSAAKTFNVTGWK 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 240 VGYGVANKKIIDYMMRVKPIFSLTRLS--QVCAITALR-DREFFERcVRDGIKS-REMLYNGLKKfKDIKVYPSEANYLL 315
Cdd:PRK07777 241 IGWACGPAPLIAAVRAAKQYLTYVGGApfQPAVAHALDhEDAWVAA-LRDSLQAkRDRLAAGLAE-AGFEVHDSAGTYFL 318
|
250 260
....*....|....*....|....*
gi 3122230 316 V----ELKTMKAKEFCEELLKR-GV 335
Cdd:PRK07777 319 CadprPLGYDDGTEFCRALPERvGV 343
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
109-357 |
2.59e-10 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 61.26 E-value: 2.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 109 RTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAK-YDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE 187
Cdd:COG1168 105 RAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENPlILEDGRYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELE 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 188 RVIN---ETDALVVID--HA--------YIEYAKkeydwtqKAPEY-DNVIVLRTFSKVFGLAGMRVGYGV-ANKKI--- 249
Cdd:COG1168 185 RLAElceRHDVLVISDeiHAdlvlpghkHTPFAS-------LSEEAaDRTITLTSPSKTFNLAGLKASYAIiPNPALrar 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 250 IDYMMRVKPIFSLTRLSQVCAITALRD-REFFERcVRDGIKS-REMLYNGLKK-FKDIKVYPSEANYLL-V---ELKtMK 322
Cdd:COG1168 258 FARALEGLGLPSPNVLGLVATEAAYREgEEWLDE-LLAYLRGnRDLLAEFLAEhLPGVKVTPPEATYLAwLdcrALG-LD 335
|
250 260 270
....*....|....*....|....*....|....*.
gi 3122230 323 AKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSIGT 357
Cdd:COG1168 336 DEELAEFLLEKaGVALSDGATFGEGGEGFVRLNFAC 371
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
14-363 |
5.53e-10 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 60.46 E-value: 5.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 14 VKKLKPYVpgksKEEI------ARAYGikpEDIIKLGSNeNPWGPSPK-IKEKILDEIDK--IHQYPEPVN-PILMKELS 83
Cdd:PRK09148 7 IRRLPPYV----FEQVnrlkaaARAAG---ADIIDLGMG-NPDLPTPQhIVDKLCETAQDprTHRYSASKGiPGLRRAQA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 84 KF------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PRK09148 79 AYyarrfgVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPAEPDEEFFPALERA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 158 LNNITDKTKVIFLCTPNNPTGNIIE---NRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIV-LRTFSK 231
Cdd:PRK09148 159 VRHSIPKPIALIVNYPSNPTAYVADldfYKDVVAFAKKHDIIILSDLAYSEiyFDGNPPPSVLQVPGAKDVTVeFTSMSK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 232 VFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDREFFERCVRDGIKS-REMLYNGLKKF 301
Cdd:PRK09148 239 TFSMAGWRMGFAVGNERLIAALTRVKsyldygaftPI-------QVAATAALNGPQDCIAEMRELYKKrRDVLVESFGRA 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 302 K-DIkvyPSEANYLLV------ELKTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRvsIGTFEEVER 363
Cdd:PRK09148 312 GwDI---PPPAASMFAwapipeAFRHLGSLEFSKLLVEKaDVAVAPGVGFGEHGDGYVR--IALVENEQR 376
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
78-237 |
1.71e-09 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 56.24 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 78 LMKELSKFLNVDEENIIV--GGDGADEiidTIFRTFVDDGDEVIIPIPTF-TQYRVSATIHNAKIKYAKYDKEKDFKLNV 154
Cdd:cd01494 5 LEEKLARLLQPGNDKAVFvpSGTGANE---AALLALLGPGDEVIVDANGHgSRYWVAAELAGAKPVPVPVDDAGYGGLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 155 ESVLNN-ITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHAYIEYAkkeydwtQKAPEYDNV-----IVLRT 228
Cdd:cd01494 82 AILEELkAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGA-------SPAPGVLIPeggadVVTFS 154
|
....*....
gi 3122230 229 FSKVFGLAG 237
Cdd:cd01494 155 LHKNLGGEG 163
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
115-256 |
2.92e-09 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 58.05 E-value: 2.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 115 GDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNII---ENRDVERVIN 191
Cdd:PRK07550 114 GDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGPGLLPDPAAAEALITPRTRAIALVTPNNPTGVVYppeLLHELYDLAR 193
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 3122230 192 ETDALVVIDHAYIEYAKK---------EYDWTqkapeyDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRV 256
Cdd:PRK07550 194 RHGIALILDETYRDFDSGggaphdlfaDPDWD------DTLVHLYSFSKSYALTGHRVGAVVASPARIAEIEKF 261
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
8-355 |
3.29e-09 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 57.87 E-value: 3.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 8 NKVRDVVKKLKPYvPGKSKEEIARAYGiKPEDIIKLGsnenpwgPSPKIKEKILDEIDKiHQY----PEPVNPILMKELS 83
Cdd:TIGR01264 14 NPIRAIVDNMKVK-PNPEKPMIKLSIG-DPTVFGNLP-------TDPEVMQAMKDSLDS-GKYngyaPTVGALSAREAIA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 84 KFL----NVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLN 159
Cdd:TIGR01264 84 SYYhnpdGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPGFPLYETLAESMGIEVKLYNLLPDKSWEIDLKQLES 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 160 NITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHAYIEYAKKEY---------DWTQKAPeydnVIVLRTFS 230
Cdd:TIGR01264 164 LIDEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFsgatfeplaSLSSTVP----ILSCGGLA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 231 KVFGLAGMRVGYGVankkIIDYMMRVKPIFS-LTRLSQV----CAIT--ALRD------REFFERcVRDGIKSREML-YN 296
Cdd:TIGR01264 240 KRWLVPGWRLGWII----IHDRRGILRDIRDgLVKLSQRilgpCTIVqgALPSillrtpQEYFDG-TLSVLESNAMLcYG 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230 297 GLKKFKDIK-VYPSEANYLLVELKTMKAK------EFCEELL-KRGVIVRDCTSFDGLGdnYVRVSI 355
Cdd:TIGR01264 315 ALAAVPGLRpVMPSGAMYMMVGIEMEHFPefkndvEFTERLVaEQSVFCLPGSCFEYPG--FFRVVL 379
|
|
| DAPAT_plant |
TIGR03542 |
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ... |
88-249 |
3.48e-08 |
|
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).
Pssm-ID: 163316 Cd Length: 402 Bit Score: 54.73 E-value: 3.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 88 VDEENIIVGgDGADEIIDTIFRTFVDDgDEVIIPIPTFTQYRVSATIHNA-----------KIKYAKYDKEKDFklnVES 156
Cdd:TIGR03542 93 IDPEEIFIS-DGAKCDVFRLQSLFGPD-NTVAVQDPVYPAYLDSNVMAGRagvldddgrysKITYLPCTAENNF---IPE 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 157 VLNNitDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY---------------IEYAKKeydwtqkap 218
Cdd:TIGR03542 168 LPEE--PHIDIIYLCSPNNPTGTVLTKEQLKELVdyaNEHGSLILFDAAYsafisdpslphsifeIPGARF--------- 236
|
170 180 190
....*....|....*....|....*....|.
gi 3122230 219 eydNVIVLRTFSKVFGLAGMRVGYGVANKKI 249
Cdd:TIGR03542 237 ---CAIEFRSFSKTAGFTGVRLGWTVVPKEL 264
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
75-242 |
3.08e-07 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 51.89 E-value: 3.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 75 NPILMKELSKFLN------VDEENIIVGgDGADEIIDTIFRTFV-DDGDEVIIPIPTFTQYrvSATIHNAKIKYAKY--D 145
Cdd:PTZ00377 117 YPFVRKAVAAFIErrdgvpKDPSDIFLT-DGASSGIKLLLQLLIgDPSDGVMIPIPQYPLY--SAAITLLGGKQVPYylD 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 146 KEKDFKLNVES--------VLNNITdkTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIE--YA----- 207
Cdd:PTZ00377 194 EEKGWSLDQEEleeayeqaVRNGIT--PRALVVINPGNPTGQVLTRDVMEEIIKfcyEKGIVLMADEVYQEniYDgekpf 271
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 3122230 208 ----KKEYDWTqkaPEYDNVIVLRTF---SK-VFGLAGMRVGY 242
Cdd:PTZ00377 272 isfrKVLLELP---AEYNTDVELVSFhstSKgIIGECGRRGGY 311
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
76-245 |
1.12e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 50.05 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 76 PILMKELSKF------LNVDEENIIV--GGDGAdeiIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKE 147
Cdd:PRK08960 72 PALREAIAGFyaqrygVDVDPERILVtpGGSGA---LLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPD 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 148 KDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIeNRD----VERVINETDALVVIDHAY--IEYakkEYDWTQKAPEYD 221
Cdd:PRK08960 149 SRYQLTPALVERHWNADTVGALVASPANPTGTLL-SRDelaaLSQALRARGGHLVVDEIYhgLTY---GVDAASVLEVDD 224
|
170 180
....*....|....*....|....
gi 3122230 222 NVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK08960 225 DAFVLNSFSKYFGMTGWRLGWLVA 248
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
98-369 |
1.32e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 49.76 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 98 DGADEIIDT------IFRTF---VDDGDEVIIPIPTFTQYR-----VSATIHNAKIKYAKYDKEKDfkLNVESVLNNITD 163
Cdd:PRK06207 100 DAADELIITpgtqgaLFLAVaatVARGDKVAIVQPDYFANRklvefFEGEMVPVQLDYLSADKRAG--LDLDQLEEAFKA 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 164 KTKVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAG 237
Cdd:PRK06207 178 GVRVFLFSNPNNPAGVVYsaeEIAQIAALARRYGATVIVDQLYsrLLYDGTSYTHLRALPIdPENVITIMGPSKTESLSG 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 238 MRVGYGVANKKIIDYMMRVKPIFSLtRLSQVCaiTALRDREFFER--CVRDGIKS----REMLYNGLKKFKDIKVYPSEA 311
Cdd:PRK06207 258 YRLGVAFGSPAIIDRMEKLQAIVSL-RAAGYS--QAVLRTWFSEPdgWMKDRIARhqaiRDDLLRVLRGVEGVFVRAPQA 334
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230 312 -NYLLVELKTMKAK--EFCEEL-LKRGVIVRDCTSFDGLGDNYVRVSI-----GTFEEVERFLKILE 369
Cdd:PRK06207 335 gSYLFPRLPRLAVSlhDFVKILrLQAGVIVTPGTEFSPHTADSIRLNFsqdhaAAVAAAERIAQLIE 401
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
111-360 |
2.10e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 49.18 E-value: 2.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 111 FVDDGDEVIIPIPTFTQYR-VSATIHNAKI-KYAKYDKEKDFKLN--VESVLNNITDKTKVIFLCTPNNPTG---NIIEN 183
Cdd:PRK08637 89 FVDQGDTVLLPDHNWGNYKlTFNTRRGAEIvTYPIFDEDGGFDTDalKEALQAAYNKGKVIVILNFPNNPTGytpTEKEA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 184 RDVERVINE-----TDALVVIDHAY--IEYAK--KEYDWTQKAPEYDNVIVLRT--FSKVFGLAGMRVG----------- 241
Cdd:PRK08637 169 TAIVEAIKEladagTKVVAVVDDAYfgLFYEDsyKESLFAALANLHSNILAVKLdgATKEEFVWGFRVGfitfgtkagss 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 242 ---YGVANKKIIDyMMRVKpIFSLTRLSQVCAITALRDREFFER--------CVRdGIKSREMLYNGlkKFKDI-KVYPS 309
Cdd:PRK08637 249 qtvKEALEKKVKG-LIRSN-ISNGPHPSQSAVLRALNSPEFDKEkqekfqilKER-YEKTKEVLYDG--KYDDAwQAYPF 323
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 310 EANYLL-VELKTMKAKEFCEELLKR---GVIvrdctsfdGLGDNYVRVSIGTFEE 360
Cdd:PRK08637 324 NSGYFMcLKLKGVDAEELRVHLLEKygiGTI--------ALNETDLRIAFSCVEE 370
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
147-352 |
3.15e-06 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 48.52 E-value: 3.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 147 EKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAkkeYDWTQKAP----- 218
Cdd:PRK07366 148 ENDFLPVFADIPTEVLAQARLMVLSYPHNPTTAIAPLSFFQEAVafcQQHDLVLVHDFPYVDLV---FDGEVEPPsilqa 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 219 --EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLTRLSQVC--AITALR-DREFFERCVRDGIKSREM 293
Cdd:PRK07366 225 dpEKSVSIEFFTLSKSYNMGGFRIGFAIGNAQLIQALRQVKAVVDFNQYRGILngAIAALTgPQATVQQTVQIFRQRRDA 304
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230 294 LYNGLKKFKDIKVYPSEANYL---LVELKTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVR 352
Cdd:PRK07366 305 FINALHQIGWPVPLPEATMYVwakLPEPWQGNSVEFCTQLVAQtGVAASPGSGFGKSGEGYVR 367
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
39-311 |
5.26e-06 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 48.15 E-value: 5.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 39 DIIKLGSNENPwgpspkikEKILDEIDKIHQYPEPVNPILMKELSKF---------------LNVDEENIIVGGdGADEI 103
Cdd:PLN02376 61 DLIKDWVKENP--------EASICTLEGIHQFSDIANFQDYHGLKKFrqaiahfmgkarggkVTFDPERVVMSG-GATGA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 104 IDTIFRTFVDDGDEVIIPIPTFTQY----RVSATIHNAKIKYAKYDkekDFKLNVESV------LNNITDKTKVIFLCTP 173
Cdd:PLN02376 132 NETIMFCLADPGDVFLIPSPYYAAFdrdlRWRTGVEIIPVPCSSSD---NFKLTVDAAdwaykkAQESNKKVKGLILTNP 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 174 NNPTGNIIEN---RDVERVINETDALVVIDHAY----------IEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PLN02376 209 SNPLGTMLDKdtlTNLVRFVTRKNIHLVVDEIYaatvfaggdfVSVAEVVNDVDISEVNVDLIHIVYSLSKDMGLPGFRV 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230 241 GYGVA-NKKIIDYMMRVKPIFSLTRLSQVCAITALRDREF-----FERCVRDGIKSReMLYNGLKKfKDIKVYPSEA 311
Cdd:PLN02376 289 GIVYSfNDSVVSCARKMSSFGLVSSQTQLMLASMLSDDQFvdnflMESSRRLGIRHK-VFTTGIKK-ADIACLTSNA 363
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
78-304 |
6.75e-06 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 47.84 E-value: 6.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 78 LMKELSKFLNVDEENIIVGGDGADEIIDTIFrtfVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PLN00145 107 LSRDLPYELSTDDIYLTAGCAQAIEIIMSVL---AQPGANILLPRPGYPLYEARAVFSGLEVRHFDLLPERGWEVDLEGV 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 158 lNNITDKTKV-IFLCTPNNPTGNIIeNRDVERVINETDA----LVVIDHAY--IEYAKKEYD----WTQKAPeydnVIVL 226
Cdd:PLN00145 184 -EALADENTVaMVIINPNNPCGSVY-SYEHLAKIAETARklgiLVIADEVYdhLTFGSKPFVpmgvFGEVAP----VLTL 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 227 RTFSKVFGLAGMRVGYGVA--------NKKIIDYMMRVKPI------FSLTRLSQVCAITalrDREFFERCVRDGIKSRE 292
Cdd:PLN00145 258 GSISKRWVVPGWRLGWIATcdpngilkETKVVDSIRNYLNIstdpatFVQGAIPQIIANT---KEEFFTKTLGLLKETAD 334
|
250
....*....|..
gi 3122230 293 MLYNGLKKFKDI 304
Cdd:PLN00145 335 ICYEKIKEIKCI 346
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
104-200 |
7.52e-06 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 47.61 E-value: 7.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 104 IDTIFRTFVDDGDEVIIPI----PTFTQYRVSATIHNAKIKYAKYDKEKDFKlnvesvlNNITDKTKVIFLCTPNNPTGN 179
Cdd:pfam01053 75 ITAAILALLKAGDHIVATDdlygGTYRLFNKVLPRFGIEVTFVDTSDPEDLE-------AAIKPNTKAVYLETPTNPLLK 147
|
90 100
....*....|....*....|.
gi 3122230 180 IIENRDVERVINETDALVVID 200
Cdd:pfam01053 148 VVDIEAIAKLAKKHGILVVVD 168
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
41-245 |
2.32e-05 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 46.02 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 41 IKLGSNEnPWGPSPK-IKEKILDEIDKIHQYPEPVN-PILMKELSKFLN-------VDEENIIVGGDGADEIIDTIFRTF 111
Cdd:PRK09147 32 ISLSIGE-PKHPTPAfIKDALAANLDGLASYPTTAGlPALREAIAAWLErryglpaLDPATQVLPVNGSREALFAFAQTV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 112 VDDGDE---VIIPIPtFTQ-YRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE 187
Cdd:PRK09147 111 IDRDGPgplVVCPNP-FYQiYEGAALLAGAEPYFLNCDPANNFAPDFDAVPAEVWARTQLLFVCSPGNPTGAVLPLDDWK 189
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 188 RVINETDAL-VVI--DHAYIE-YakkeYDwTQKAP-------------EYDNVIVLRTFSKVFGLAGMRVGYgVA 245
Cdd:PRK09147 190 KLFALSDRYgFVIasDECYSEiY----FD-EAAPPlglleaaaelgrdDFKRLVVFHSLSKRSNVPGLRSGF-VA 258
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
78-337 |
2.78e-05 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 45.77 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 78 LMKELSKFLNVDEENIIVGGDGADEIIdtiFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PLN00143 87 LSNDLPYQLSPDDVYLTLGCKHAAEII---IKVLARPEANILLPRPGFPDVETYAIFHHLEIRHFDLLPEKGWEVDLDAV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 158 LNNITDKTKVIFLCTPNNPTGNIIENRDVERvINET----DALVVIDHAY--IEYAKKEYDWTQKAPEYDNVIVLRTFSK 231
Cdd:PLN00143 164 EAIADENTIAMVIINPGNPCGSVYSYEHLNK-IAETarklGILVIADEVYghIVFGSKPFVPMGLFASIVPVITLGSISK 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 232 VFGLAGMRVGY-------------GVAN--KKIIDYmMRVKPIFSLTRLSQVCAITAlrdREFFERCVRDGIKSREMLYN 296
Cdd:PLN00143 243 RWMIPGWGLGWlvtcdpsgllqicEIADsiKKALNP-APFPPTFIQAAIPEILEKTT---EDFFSKTINILRAALAFCYD 318
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 3122230 297 GLKKFKDIKV--YPSEANYLLVELKTMKAK------EFCEELLKRGVIV 337
Cdd:PLN00143 319 KLKEIPCIMCpqKAEGAFFALVKLNLLLLEdieddmEFCLKLAKEESLI 367
|
|
| PTZ00376 |
PTZ00376 |
aspartate aminotransferase; Provisional |
58-241 |
4.50e-05 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 240390 Cd Length: 404 Bit Score: 44.91 E-value: 4.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 58 EKILDEIDKIHQYPePVNPI-LMKELSKFL-------NVDEENII----VGGDGADEIIDTIFRTFVDDGDEVIIPIPTF 125
Cdd:PTZ00376 56 EKIIAEKNLDKEYL-PIEGLqSFIEAAQKLlfgeasyALAEKRIAtvqaLSGTGALRLGFEFLKRFLPAGTTVYVSNPTW 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 126 TQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLN---NITDKTKVIFLCTPNNPTG---NIIENRDVERVINETDALVVI 199
Cdd:PTZ00376 135 PNHVNIFKSAGLNVKEYRYYDPKTKGLDFDGMLEdlrTAPNGSVVLLHACAHNPTGvdpTEEQWKEIADVMKRKNLIPFF 214
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 3122230 200 DHAYIEYAKK--EYD------WTQKAPEydnVIVLRTFSKVFGLAGMRVG 241
Cdd:PTZ00376 215 DMAYQGFASGdlDKDayairlFAERGVE---FLVAQSFSKNMGLYGERIG 261
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
104-200 |
4.56e-05 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 45.02 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 104 IDTIFRTFVDDGDEVIIPIPTFT-QYRVSATIHNA-KIKYAKYDKEkdfklNVESVLNNITDKTKVIFLCTPNNPTGNII 181
Cdd:PRK07811 89 TDCLLRAVLRPGDHIVIPNDAYGgTFRLIDKVFTRwGVEYTPVDLS-----DLDAVRAAITPRTKLIWVETPTNPLLSIT 163
|
90
....*....|....*....
gi 3122230 182 ENRDVERVINETDALVVID 200
Cdd:PRK07811 164 DIAALAELAHDAGAKVVVD 182
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
84-372 |
5.50e-05 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 44.74 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 84 KFLNVDEENIIVGGDGADEIIDTIFRTF--VDDGDEVIIP--------IPtftqYRVSATIHNAKIKYAKYDKekDFKLN 153
Cdd:COG0520 70 RFIGAASPDEIIFTRGTTEAINLVAYGLgrLKPGDEILITemehhsniVP----WQELAERTGAEVRVIPLDE--DGELD 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 154 VESVLNNITDKTKVIFLC-TPNNpTGNIIenrDVERVI---NETDALVVIDHAyieyakkeydwtQKAPEYD-NVIVLR- 227
Cdd:COG0520 144 LEALEALLTPRTKLVAVThVSNV-TGTVN---PVKEIAalaHAHGALVLVDGA------------QSVPHLPvDVQALGc 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 228 ---TFS--KVFGLAGMRVGYGvaNKKIIDYMmrvKPIF---------SLTR----------------LSQVCAI-TALrd 276
Cdd:COG0520 208 dfyAFSghKLYGPTGIGVLYG--KRELLEAL---PPFLggggmiewvSFDGttyadlprrfeagtpnIAGAIGLgAAI-- 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 277 rEFFERCVRDGIKSREM-----LYNGLKKFKDIKVY-PSEANYLL----VELKTMKAKEFCEELLKRGVIVRD---CTS- 342
Cdd:COG0520 281 -DYLEAIGMEAIEAREReltayALEGLAAIPGVRILgPADPEDRSgivsFNVDGVHPHDVAALLDDEGIAVRAghhCAQp 359
|
330 340 350
....*....|....*....|....*....|....*
gi 3122230 343 -FDGLG-DNYVRVSIG---TFEEVERFLKILEEII 372
Cdd:COG0520 360 lMRRLGvPGTVRASFHlynTEEEIDRLVEALKKLA 394
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
80-202 |
7.16e-05 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 44.55 E-value: 7.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 80 KELSKFLNV-DEENIIV--GGDGADEIIDTIFRTFVDDGDEVIIpiptfTQYRVSATI---------HNAKIKYAKYDKe 147
Cdd:pfam00266 50 EKVAEFINApSNDEIIFtsGTTEAINLVALSLGRSLKPGDEIVI-----TEMEHHANLvpwqelakrTGARVRVLPLDE- 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 3122230 148 kDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHA 202
Cdd:pfam00266 124 -DGLLDLDELEKLITPKTKLVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAA 177
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
53-304 |
8.54e-05 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 44.14 E-value: 8.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 53 SPKIKEKILDEI--DKIHQYPEPVN-PILMKELSKFLNVD------EENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIP 123
Cdd:PLN02656 50 THVAQEAVVDALqsNKFNGYAPTVGlPQARRAIAEYLSRDlpyklsLDDVFIT-SGCTQAIDVALSMLARPGANILLPRP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 124 TFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVINETDAL---VVID 200
Cdd:PLN02656 129 GFPIYELCAAFRHLEVRYVDLLPEKGWEVDLDAVEALADQNTVALVIINPGNPCGNVYSYQHLKKIAETAEKLkilVIAD 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 201 HAY--IEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVA--------NKKIIDymmRVKPIFSLTR------ 264
Cdd:PLN02656 209 EVYghLAFGSNPFVPMGVFGSIVPVLTLGSLSKRWIVPGWRLGWFVTtdpsgsfrDPKIVE---RIKKYFDILGgpatfi 285
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 3122230 265 LSQVCAITALRDREFFERCVrdgiksremlyNGLKKFKDI 304
Cdd:PLN02656 286 QAAVPTILEQTDESFFKKTI-----------NILKQSSDI 314
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
104-200 |
8.91e-05 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 44.12 E-value: 8.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 104 IDTIFRTFVDDGDEVIIPI----PTFTQYRVSATIHNAKIKYAkydkekDFkLNVESVLNNITDKTKVIFLCTPNNPTGN 179
Cdd:cd00614 68 ISTVLLALLKAGDHVVASDdlygGTYRLFERLLPKLGIEVTFV------DP-DDPEALEAAIKPETKLVYVESPTNPTLK 140
|
90 100
....*....|....*....|.
gi 3122230 180 IIENRDVERVINETDALVVID 200
Cdd:cd00614 141 VVDIEAIAELAHEHGALLVVD 161
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
194-371 |
1.17e-04 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 43.70 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 194 DALVVID--HAY---------IEYAKKEYDwtqkapeyDNVIVLRTFSKVFGLAGmrvGYGVANKKIIDYMMRVKP--IF 260
Cdd:cd06454 162 GAILFVDeaHSVgvygphgrgVEEFGGLTD--------DVDIIMGTLGKAFGAVG---GYIAGSKELIDYLRSYARgfIF 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 261 SLTRLSQVCA--ITALRdrefferCVRDGIKSREMLYNGLKKFK------DIKVYPSE--ANYLLVELKTMKAKEFCEEL 330
Cdd:cd06454 231 STSLPPAVAAaaLAALE-------VLQGGPERRERLQENVRYLRrglkelGFPVGGSPshIIPPLIGDDPAKAVAFSDAL 303
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 3122230 331 LKRGVIVRDC----TSfdgLGDNYVRVSIG---TFEEVERFLKILEEI 371
Cdd:cd06454 304 LERGIYVQAIryptVP---RGTARLRISLSaahTKEDIDRLLEALKEV 348
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
104-200 |
2.79e-04 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 42.73 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 104 IDTIFRTFVDDGDEVIIP----IPT-------FTQYRVSATIHNAkikyakydkekdfkLNVESVLNNITDKTKVIFLCT 172
Cdd:COG0626 86 ISAVLLALLKAGDHVVASddlyGGTrrlldkvLARFGIEVTFVDP--------------TDLAAVEAAIRPNTKLVFLET 151
|
90 100 110
....*....|....*....|....*....|.
gi 3122230 173 PNNPTGNIIenrDVERVIN---ETDALVVID 200
Cdd:COG0626 152 PSNPTLEVV---DIAAIAAiahAAGALLVVD 179
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
97-203 |
3.52e-04 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 42.48 E-value: 3.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 97 GDGAdeiIDTIFRTFVDDGDEVIIpipTFTQYRVS-ATIHNAKIKYAKYDKEKDFKlNVESVLNNITDKTKVIFLCTPNN 175
Cdd:PRK07503 89 GMGA---ITATLWTLLRPGDEVIV---DQTLYGCTfAFLHHGLGEFGVTVRHVDLT-DPAALKAAISDKTRMVYFETPAN 161
|
90 100
....*....|....*....|....*...
gi 3122230 176 PTGNIIENRDVERVINETDALVVIDHAY 203
Cdd:PRK07503 162 PNMRLVDIAAVAEIAHGAGAKVVVDNTY 189
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
99-246 |
4.41e-04 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 42.02 E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTG 178
Cdd:PLN02187 139 GCNQGIEIVFESLARPNANILLPRPGFPHYDARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADENTVAMVVINPNNPCG 218
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230 179 NIIENRDVERVINETDAL---VVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PLN02187 219 NVYSHDHLKKVAETARKLgimVISDEVYDRtiFGDNPFVSMGKFASIVPVLTLAGISKGWVVPGWKIGWIALN 291
|
|
| PRK05958 |
PRK05958 |
8-amino-7-oxononanoate synthase; Reviewed |
221-273 |
4.76e-03 |
|
8-amino-7-oxononanoate synthase; Reviewed
Pssm-ID: 235655 [Multi-domain] Cd Length: 385 Bit Score: 38.60 E-value: 4.76e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230 221 DNVIVLRTFSKVFGLAGmrvGYGVANKKIIDYMM-RVKP-IFSlTRLS--QVCAITA 273
Cdd:PRK05958 229 PDVILVGTLGKALGSSG---AAVLGSETLIDYLInRARPfIFT-TALPpaQAAAARA 281
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
121-371 |
7.71e-03 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 38.13 E-value: 7.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 121 PIPTFTQYRVSATIHNAKIKYAKYDKEKDFKlnvesvlNNITDKT----KVIFLCTPNNPTGNIIenrDVERVIN----- 191
Cdd:PRK05839 115 PNPFYQIYEGAAIASRAKVLLMPLTKENDFT-------PSLNEKElqevDLVILNSPNNPTGRTL---SLEELIEwvkla 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 192 -ETDALVVIDHAYIE-YAKkeydwtQKAP------------EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK 257
Cdd:PRK05839 185 lKHDFILINDECYSEiYEN------TPPPslleasilvgneSFKNVLVINSISKRSSAPGLRSGFIAGDASILKKYKAYR 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230 258 ---------PIfsltrlsQVCAITALRDREFFErcvrdgiKSREMLYNGLKKFKDI-KVYPSEANYlLVELKTMKAKEFC 327
Cdd:PRK05839 259 tylgcasplPL-------QKAAAVAWLDDEHAE-------FFRNIYAKNLKLAREIlGITIPPATF-YVWLPVDNDEEFT 323
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 3122230 328 EELLKRGVIVRDCTSF---DGLGDNYVRvsIGTFEEVERFLKILEEI 371
Cdd:PRK05839 324 KKLYQNEGIKVLPGSFlgrNGIGKGYVR--IALVYDTPKLEKALEII 368
|
|
|