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Conserved domains on  [gi|3122230|sp|Q58365|]
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RecName: Full=Histidinol-phosphate aminotransferase; AltName: Full=Imidazole acetol-phosphate transaminase

Protein Classification

histidinol-phosphate transaminase( domain architecture ID 11490209)

histidinol-phosphate transaminase is a pyridoxal phosphate (PLP)-dependent aminotransferase that catalyzes the reversible transfer of the amino group from glutamate to imidazole acetol-phosphate producing 2-oxoglutarate and histidinol phosphate

CATH:  3.40.640.10
EC:  2.6.1.9
Gene Symbol:  hisC
Gene Ontology:  GO:0004400|GO:0030170|GO:0000105
PubMed:  10800595
SCOP:  4000670

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
11-371 8.19e-176

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


:

Pssm-ID: 273467  Cd Length: 350  Bit Score: 492.55  E-value: 8.19e-176
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     11 RDVVKKLKPYVPGkskeeiARAYGIKpeDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDE 90
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGD--EVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDP 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     91 ENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFL 170
Cdd:TIGR01141  73 EQILLG-NGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDE--DGQLDLEDILVAIDDKPKLVFL 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    171 CTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:TIGR01141 150 CSPNNPTGNLFSRGDIEAVLERTpgDALVVVDEAYGEFSG-EPSTLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKTMkAKEFCE 328
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPGLEVYPSDANFVLIRFPGD-ADALFE 307
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 3122230    329 ELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYPGLLPNCLRITVGTREENDRFLAALREI 350
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
11-371 8.19e-176

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 492.55  E-value: 8.19e-176
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     11 RDVVKKLKPYVPGkskeeiARAYGIKpeDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDE 90
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGD--EVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDP 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     91 ENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFL 170
Cdd:TIGR01141  73 EQILLG-NGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDE--DGQLDLEDILVAIDDKPKLVFL 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    171 CTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:TIGR01141 150 CSPNNPTGNLFSRGDIEAVLERTpgDALVVVDEAYGEFSG-EPSTLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKTMkAKEFCE 328
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPGLEVYPSDANFVLIRFPGD-ADALFE 307
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 3122230    329 ELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYPGLLPNCLRITVGTREENDRFLAALREI 350
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
18-371 6.61e-145

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 413.76  E-value: 6.61e-145
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   18 KPYVPGKSKEEiaraygikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGg 97
Cdd:COG0079   1 SPYVPGGPIEE--------PEDIIKLSSNENPYGPPPKVLEAIAAALDALNRYPDPDATALREALAEYYGVPPEQVLVG- 71
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   98 DGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFLCTPNNPT 177
Cdd:COG0079  72 NGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLDE--DFSLDLDALLAAITERTDLVFLCNPNNPT 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  178 GNIIENRDVERVINET--DALVVIDHAYIEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMR 255
Cdd:COG0079 150 GTLLPREELEALLEALpaDGLVVVDEAYAEFVPEEDSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRR 229
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  256 VKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKdIKVYPSEANYLLVELKtMKAKEFCEELLKRGV 335
Cdd:COG0079 230 VRGPWNVNSLAQAAALAALEDRAYLEETRARLRAERERLAAALRALG-LTVYPSQANFVLVRVP-EDAAELFEALLERGI 307
                       330       340       350
                ....*....|....*....|....*....|....*.
gi 3122230  336 IVRDCTSFdGLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:COG0079 308 LVRDFSSF-GL-PDYLRITVGTPEENDRLLAALKEI 341
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
10-371 2.29e-98

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 296.99  E-value: 2.29e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    10 VRDVVKKLKPYVPGKSKEEIARAYGIKPEDIIKLGSNENPWGPSPKIKEKiLDEIDKIHQYPEPVNPILMKELSKFLNVD 89
Cdd:PLN03026  24 IRKHILQLAPYQPILPFEVLSAQLGRKPEDIVKLDANENPYGPPPEVLEA-LGNMKFPYVYPDPESRRLRAALAEDSGLE 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    90 EENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIkyAKYDKEKDFKLNVESVLNNI-TDKTKVI 168
Cdd:PLN03026 103 SENILVGC-GADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEV--IKVPRTPDFSLDVPRIVEAVeTHKPKLL 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   169 FLCTPNNPTGNIIENRDVERVInETDALVVIDHAYIEYAKKEyDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:PLN03026 180 FLTSPNNPDGSIISDDDLLKIL-ELPILVVLDEAYIEFSTQE-SRMKWVKKYDNLIVLRTFSKRAGLAGLRVGYGAFPLS 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKT-MKAKEFC 327
Cdd:PLN03026 258 IIEYLWRAKQPYNVSVAAEVAACAALSNPKYLEDVKNALVEERERLFGLLKEVPFLEPYPSDANFILCRVTSgRDAKKLK 337
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 3122230   328 EELLKRGVIVRDCTSFDglGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PLN03026 338 EDLAKMGVMVRHYNSKE--LKGYIRVSVGKPEHTDALMEALKQL 379
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
41-370 1.10e-85

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 263.43  E-value: 1.10e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   41 IKLGSNENPWGPSPKIKEKILDEIDK---IHQYPEPVNPILMKELSKFLN------VDEENIIVGgDGADEIIDTIFRTF 111
Cdd:cd00609   1 IDLSIGEPDFPPPPEVLEALAAAALRaglLGYYPDPGLPELREAIAEWLGrrggvdVPPEEIVVT-NGAQEALSLLLRAL 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  112 VDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI- 190
Cdd:cd00609  80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAe 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  191 --NETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSL---T 263
Cdd:cd00609 160 laKKHGILIISDEAYAElvYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYTTsgpS 239
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  264 RLSQVCAITALRDR-EFFERCVRDGIKSREMLYNGLKK-FKDIKVYPSEANYLLVELKTMKAKEFCEELL-KRGVIVRDC 340
Cdd:cd00609 240 TLSQAAAAAALDDGeEHLEELRERYRRRRDALLEALKElGPLVVVKPSGGFFLWLDLPEGDDEEFLERLLlEAGVVVRPG 319
                       330       340       350
                ....*....|....*....|....*....|.
gi 3122230  341 TSFDGLGDNYVRVSIGT-FEEVERFLKILEE 370
Cdd:cd00609 320 SAFGEGGEGFVRLSFATpEEELEEALERLAE 350
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
38-368 4.94e-68

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 217.94  E-value: 4.94e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     38 EDIIKLGSNENPWGPSPKIKEKILDEID--KIHQYPEP-VNPILMKELSKFLNVD-------EENIIVGGdGADEIIDTI 107
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAVAKAEKDALAggTRNLYGPTdGHPELREALAKFLGRSpvlkldrEAAVVFGS-GAGANIEAL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    108 FRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNII---ENR 184
Cdd:pfam00155  80 IFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVAtleELE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    185 DVERVINETDALVVIDHAYIEYAKKEYDWTQKAP---EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFS 261
Cdd:pfam00155 160 KLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRAllaEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARPFY 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    262 LTRLSQVCAITALRDREFFERCV---RDGIKS-REMLYNGLKKfKDIKVYPSEAN-YLLVELKTMKAKEFCEELLKR-GV 335
Cdd:pfam00155 240 SSTHLQAAAAAALSDPLLVASELeemRQRIKErRDYLRDGLQA-AGLSVLPSQAGfFLLTGLDPETAKELAQVLLEEvGV 318
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 3122230    336 IVRDCTSFdgLGDNYVRVSI--GTFEEVERFLKIL 368
Cdd:pfam00155 319 YVTPGSSP--GVPGWLRITVagGTEEELEELLEAI 351
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
76-371 1.50e-43

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 154.42  E-value: 1.50e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    76 PILMKELSKFL------NVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKY-DKEK 148
Cdd:NF041364  40 LELREAIAALYkdgygiEVSPDQVLVT-TGASEALFLYFHALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLPLsPENQ 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYA-KKEYDWTQKAPEYDN 222
Cdd:NF041364 119 GFRPDLEALRSLITPRTRAIVINSPNNPTGAVMTEAELEAILEiasRHGLIVLADEHYrfLPYDdGKHVSPSLYPGLSER 198
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   223 VIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK--PIFSLTRLSQVCAITALRDREffERCVRDGIKS----REMLYN 296
Cdd:NF041364 199 VIALGSFSKTYGMTGLRVGWLIGPKELIGAILKFKdyTTHCAPSISQYAALEALEQGP--QERVKGWVREnvrrRDALVE 276
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230   297 GLKKFKDIKVYPSEANYLLVELK-TMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSIGtfEEVERFLKILEEI 371
Cdd:NF041364 277 RLERLIGWVCEPEGGFYAFPKLKdGLPSAAFAEELLeKAGVVVLPGSAFGRPGEGYFRIGFA--NSPTRLKEALERL 351
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
11-371 8.19e-176

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 492.55  E-value: 8.19e-176
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     11 RDVVKKLKPYVPGkskeeiARAYGIKpeDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDE 90
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGD--EVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDP 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     91 ENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFL 170
Cdd:TIGR01141  73 EQILLG-NGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDE--DGQLDLEDILVAIDDKPKLVFL 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    171 CTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:TIGR01141 150 CSPNNPTGNLFSRGDIEAVLERTpgDALVVVDEAYGEFSG-EPSTLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKTMkAKEFCE 328
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPGLEVYPSDANFVLIRFPGD-ADALFE 307
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 3122230    329 ELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYPGLLPNCLRITVGTREENDRFLAALREI 350
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
18-371 6.61e-145

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 413.76  E-value: 6.61e-145
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   18 KPYVPGKSKEEiaraygikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGg 97
Cdd:COG0079   1 SPYVPGGPIEE--------PEDIIKLSSNENPYGPPPKVLEAIAAALDALNRYPDPDATALREALAEYYGVPPEQVLVG- 71
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   98 DGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFLCTPNNPT 177
Cdd:COG0079  72 NGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLDE--DFSLDLDALLAAITERTDLVFLCNPNNPT 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  178 GNIIENRDVERVINET--DALVVIDHAYIEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMR 255
Cdd:COG0079 150 GTLLPREELEALLEALpaDGLVVVDEAYAEFVPEEDSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRR 229
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  256 VKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKdIKVYPSEANYLLVELKtMKAKEFCEELLKRGV 335
Cdd:COG0079 230 VRGPWNVNSLAQAAALAALEDRAYLEETRARLRAERERLAAALRALG-LTVYPSQANFVLVRVP-EDAAELFEALLERGI 307
                       330       340       350
                ....*....|....*....|....*....|....*.
gi 3122230  336 IVRDCTSFdGLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:COG0079 308 LVRDFSSF-GL-PDYLRITVGTPEENDRLLAALKEI 341
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
10-371 2.29e-98

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 296.99  E-value: 2.29e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    10 VRDVVKKLKPYVPGKSKEEIARAYGIKPEDIIKLGSNENPWGPSPKIKEKiLDEIDKIHQYPEPVNPILMKELSKFLNVD 89
Cdd:PLN03026  24 IRKHILQLAPYQPILPFEVLSAQLGRKPEDIVKLDANENPYGPPPEVLEA-LGNMKFPYVYPDPESRRLRAALAEDSGLE 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    90 EENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIkyAKYDKEKDFKLNVESVLNNI-TDKTKVI 168
Cdd:PLN03026 103 SENILVGC-GADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEV--IKVPRTPDFSLDVPRIVEAVeTHKPKLL 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   169 FLCTPNNPTGNIIENRDVERVInETDALVVIDHAYIEYAKKEyDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKK 248
Cdd:PLN03026 180 FLTSPNNPDGSIISDDDLLKIL-ELPILVVLDEAYIEFSTQE-SRMKWVKKYDNLIVLRTFSKRAGLAGLRVGYGAFPLS 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   249 IIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKT-MKAKEFC 327
Cdd:PLN03026 258 IIEYLWRAKQPYNVSVAAEVAACAALSNPKYLEDVKNALVEERERLFGLLKEVPFLEPYPSDANFILCRVTSgRDAKKLK 337
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 3122230   328 EELLKRGVIVRDCTSFDglGDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PLN03026 338 EDLAKMGVMVRHYNSKE--LKGYIRVSVGKPEHTDALMEALKQL 379
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
41-370 1.10e-85

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 263.43  E-value: 1.10e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   41 IKLGSNENPWGPSPKIKEKILDEIDK---IHQYPEPVNPILMKELSKFLN------VDEENIIVGgDGADEIIDTIFRTF 111
Cdd:cd00609   1 IDLSIGEPDFPPPPEVLEALAAAALRaglLGYYPDPGLPELREAIAEWLGrrggvdVPPEEIVVT-NGAQEALSLLLRAL 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  112 VDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI- 190
Cdd:cd00609  80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAe 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  191 --NETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSL---T 263
Cdd:cd00609 160 laKKHGILIISDEAYAElvYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYTTsgpS 239
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  264 RLSQVCAITALRDR-EFFERCVRDGIKSREMLYNGLKK-FKDIKVYPSEANYLLVELKTMKAKEFCEELL-KRGVIVRDC 340
Cdd:cd00609 240 TLSQAAAAAALDDGeEHLEELRERYRRRRDALLEALKElGPLVVVKPSGGFFLWLDLPEGDDEEFLERLLlEAGVVVRPG 319
                       330       340       350
                ....*....|....*....|....*....|.
gi 3122230  341 TSFDGLGDNYVRVSIGT-FEEVERFLKILEE 370
Cdd:cd00609 320 SAFGEGGEGFVRLSFATpEEELEEALERLAE 350
PRK03321 PRK03321
putative aminotransferase; Provisional
9-373 1.79e-71

putative aminotransferase; Provisional


Pssm-ID: 179559  Cd Length: 352  Bit Score: 227.16  E-value: 1.79e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     9 KVRDVVKKLKPYVPGKSkeeiaraygikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNV 88
Cdd:PRK03321   4 RLRPDLAGIPAYVPGKT-----------VPGAIKLSSNETPFGPLPSVRAAIARAAAGVNRYPDMGAVELRAALAEHLGV 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    89 DEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKikYAKYDKEKDFKLNVESVLNNITDKTKVI 168
Cdd:PRK03321  73 PPEHVAVGC-GSVALCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGAT--PVQVPLTPDHTHDLDAMAAAITDRTRLI 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   169 FLCTPNNPTGNIIENRDVERVINET--DALVVIDHAYIEYAKKEY--DWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGV 244
Cdd:PRK03321 150 FVCNPNNPTGTVVTPAELARFLDAVpaDVLVVLDEAYVEYVRDDDvpDGLELVRDHPNVVVLRTFSKAYGLAGLRVGYAV 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   245 ANKKIIDYMMRVKPIFSLTRLSQVCAITALRDR-EFFERcVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKA 323
Cdd:PRK03321 230 GHPEVIAALRKVAVPFSVNSLAQAAAIASLAAEdELLER-VDAVVAERDRVRAALRA-AGWTVPPSQANFVWLPLGE-RT 306
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 3122230   324 KEFCEELLKRGVIVRdctSFDGLGdnyVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK03321 307 ADFAAAAAEAGVVVR---PFAGEG---VRVTIGAPEENDAFLRAARAWRA 350
PRK05166 PRK05166
histidinol-phosphate transaminase;
10-371 8.91e-69

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 220.78  E-value: 8.91e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    10 VRDVVKKLKPYVPGKSKEEIARAYGikPEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVD 89
Cdd:PRK05166  10 ARAEVRPLPPYNAGLTIEEVRARYG--VPRIAKLGSNENPLGPSPAVRRAFADIAELLRLYPDPQGRALREAIAARTGVP 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    90 EENIIVgGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKyaKYDKEKDFKLNVESVLNNITDKTKVIF 169
Cdd:PRK05166  88 ADRIIL-GNGSEDLIAVICRAVLRPGDRVVTLYPSFPLHEDYPTMMGARVE--RVTVTPDLGFDLDALCAAVARAPRMLM 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   170 LCTPNNPTGNIIENRDVERVINETDA--LVVIDHAYIEYAKKEyDWTQKAPEYDNV----IVLRTFSKVFGLAGMRVGYG 243
Cdd:PRK05166 165 FSNPSNPVGSWLTADQLARVLDATPPetLIVVDEAYAEYAAGD-DYPSALTLLKARglpwIVLRTFSKAYGLAGLRVGYG 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   244 -VANKKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmK 322
Cdd:PRK05166 244 lVSDPELVGLLDRVRTPFNVNGAAQAAALAALDDEEHLAKGVALALAERERLKKELAE-MGYRIAPSRANFLFFDARR-P 321
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 3122230   323 AKEFCEELLKRGVIVRDCTSfDGLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK05166 322 ASAVAEALLRQGVIVKPWKQ-PGF-ETFIRVSIGSPEENDHFVAALDKV 368
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
38-368 4.94e-68

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 217.94  E-value: 4.94e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     38 EDIIKLGSNENPWGPSPKIKEKILDEID--KIHQYPEP-VNPILMKELSKFLNVD-------EENIIVGGdGADEIIDTI 107
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAVAKAEKDALAggTRNLYGPTdGHPELREALAKFLGRSpvlkldrEAAVVFGS-GAGANIEAL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    108 FRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNII---ENR 184
Cdd:pfam00155  80 IFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVAtleELE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    185 DVERVINETDALVVIDHAYIEYAKKEYDWTQKAP---EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFS 261
Cdd:pfam00155 160 KLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRAllaEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARPFY 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    262 LTRLSQVCAITALRDREFFERCV---RDGIKS-REMLYNGLKKfKDIKVYPSEAN-YLLVELKTMKAKEFCEELLKR-GV 335
Cdd:pfam00155 240 SSTHLQAAAAAALSDPLLVASELeemRQRIKErRDYLRDGLQA-AGLSVLPSQAGfFLLTGLDPETAKELAQVLLEEvGV 318
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 3122230    336 IVRDCTSFdgLGDNYVRVSI--GTFEEVERFLKIL 368
Cdd:pfam00155 319 YVTPGSSP--GVPGWLRITVagGTEEELEELLEAI 351
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
14-371 4.26e-60

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 198.43  E-value: 4.26e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   14 VKKLKPYVPGKSKEEiARAYGIKPEDIIKLGSNENPWGPSPKIKEKILDEIDK-IHQYPePVN--PILMKELSKF----- 85
Cdd:COG0436   7 LARLPPSPIREVSAL-AAELKAAGEDVIDLGIGEPDFPTPDHIREAAIEALDDgVTGYT-PSAgiPELREAIAAYykrry 84
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   86 -LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDK 164
Cdd:COG0436  85 gVDLDPDEILVTN-GAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDPEALEAAITPR 163
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  165 TKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAGM 238
Cdd:COG0436 164 TKAIVLNSPNNPTGAVYSREELEALAelaREHDLLVISDEIYeeLVYDGAEHVSILSLPGlKDRTIVINSFSKSYAMTGW 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  239 RVGYGVANKKIIDYMMRVK--PIFSLTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFkDIKVYPSEAN-YL 314
Cdd:COG0436 244 RIGYAVGPPELIAALLKLQsnLTSCAPTPAQYAAAAALEgPQDYVEEMRAEYRRRRDLLVEGLNEI-GLSVVKPEGAfYL 322
                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230  315 LVELK--TMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVS----IGTFEE-VERFLKILEEI 371
Cdd:COG0436 323 FADVPelGLDSEEFAERLLeEAGVAVVPGSAFGPAGEGYVRISyatsEERLEEaLERLARFLERY 387
L_thr_O3P_dcar TIGR01140
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ...
28-368 5.71e-52

L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273466  Cd Length: 330  Bit Score: 175.84  E-value: 5.71e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     28 EIARAYGIKPEDIIKLGSNENPWG-PSPKIkekildEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGADEIIDT 106
Cdd:TIGR01140   7 RAAARYGIPPEDWLDLSTGINPLGpPVPPI------PLSAWARYPDPEYDELRAAAAAYYGLPAASVLPVN-GAQEAIYL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    107 IFRTFvdDGDEVIIPIPTFTQYRVSATIHNAKIKYAkYDKEKdfklnVESVLnnitDKTKVIFLCTPNNPTGNIIENRDV 186
Cdd:TIGR01140  80 LPRLL--APGRVLVLAPTYSEYARAWRAAGHEVVEL-PDLDR-----LPAAL----EEADLLVVCNPNNPTGRLIPPETL 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    187 ERVIN---ETDALVVIDHAYIEYAkKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLT 263
Cdd:TIGR01140 148 LALAArlrARGGWLVVDEAFIDFT-PDASLAPQAARFPGLVVLRSLTKFFGLAGLRLGFVVAHPALIARLREALGPWTVN 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    264 RLSQVCAITALRDREFFERcVRDGIKS-REMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTS 342
Cdd:TIGR01140 227 GPALAAGRAALADTAWQAA-TRARLAAeRARLAALLARLGGLRVVGGTALFLLVRTP--DAAALHEALARRGILIRDFDN 303
                         330       340
                  ....*....|....*....|....*.
gi 3122230    343 FDGLGDNYVRVSIGTFEEVERFLKIL 368
Cdd:TIGR01140 304 FPGLDPRYLRFALPTDEENDRLLEAL 329
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
41-371 9.46e-52

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 176.21  E-value: 9.46e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    41 IKLGSNENPWGPSPKIKEKILDEIDKI----HQYPEPVNPILMKELSKFLN------VDEENIIvGGDGADEIIDTIFRT 110
Cdd:PRK03317  29 VRLNTNENPYPPSPALVADIAEAVAEAaaglNRYPDRDAVALRADLAAYLTaqtgvgLTVENVW-AANGSNEILQQLLQA 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   111 FVDDGDEVIIPIPTFTQYRVSAtiHNAKIKYAKYDKEKDFKLNVESVLNNITD-KTKVIFLCTPNNPTGNIIENRDVERV 189
Cdd:PRK03317 108 FGGPGRTALGFVPSYSMHPIIA--RGTHTEWVEGPRAADFTLDVDAAVAAIAEhRPDVVFLTSPNNPTGTALPLDDVEAI 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   190 INETDALVVIDHAYIEYAKkeyDWTQKA----PEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLTRL 265
Cdd:PRK03317 186 LDAAPGIVVVDEAYAEFRR---SGTPSAltllPEYPRLVVSRTMSKAFAFAGGRLGYLAAAPAVVDALRLVRLPYHLSAV 262
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   266 SQVCAITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKAKEFCEELLKRGVIVRDcTSFDG 345
Cdd:PRK03317 263 TQAAARAALRHADELLASVAALRAERDRVVAWLRE-LGLRVAPSDANFVLFGRFA-DRHAVWQGLLDRGVLIRD-VGIPG 339
                        330       340
                 ....*....|....*....|....*.
gi 3122230   346 lgdnYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK03317 340 ----WLRVTIGTPEENDAFLAALAEV 361
PRK02610 PRK02610
histidinol-phosphate transaminase;
17-372 2.13e-44

histidinol-phosphate transaminase;


Pssm-ID: 235053  Cd Length: 374  Bit Score: 157.18  E-value: 2.13e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    17 LKPYVPGKSKEEIARAygiKPEDiiKLGSNENPWGPSPKIKEKILDEIDKI---HQYPEPVNPILMKELSKFLN------ 87
Cdd:PRK02610  12 LKAYHPHPSGDADDAV---IQLD--RLDTNEFPYDLPPDLKQKLAWLYQQGiesNRYPDGGHEALKQAIAEYVNesaags 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    88 --VDEENIIVGgDGADEIIDTIF-RTFVDDGDEVIIPIPTFTQYRVSA-TIHNAKIKYAKydKEKDFKLNVESVLNNITD 163
Cdd:PRK02610  87 sqITPANISVG-NGSDELIRSLLiATCLGGEGSILVAEPTFSMYGILAqTLGIPVVRVGR--DPETFEIDLAAAQSAIEQ 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   164 KT----KVIFLCTPNNPTGNIIENRDVERVIN-ETDALVVIDHAYIEYAKKEYdwTQKAPEYDNVIVLRTFSKVFGLAGM 238
Cdd:PRK02610 164 TQnppvRVVFVVHPNSPTGNPLTAAELEWLRSlPEDILVVIDEAYFEFSQTTL--VGELAQHPNWVILRTFSKAFRLAAH 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   239 RVGYGVANKKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVEL 318
Cdd:PRK02610 242 RVGYAIGHPELIAVLEKVRLPYNLPSFSQLAAQLALEHRQELLAAIPEILQERDRLYQALQELPQLRVWPSAANFLYLRL 321
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 3122230   319 KTMKA-KEFCEELLKRGVIVRdCTSfDGLgdnyvRVSIGTFEEVERFLKILEEII 372
Cdd:PRK02610 322 SQDAAlAALHQALKAQGTLVR-HTG-GGL-----RITIGTPEENQRTLERLQAAL 369
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
76-371 1.50e-43

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 154.42  E-value: 1.50e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    76 PILMKELSKFL------NVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKY-DKEK 148
Cdd:NF041364  40 LELREAIAALYkdgygiEVSPDQVLVT-TGASEALFLYFHALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLPLsPENQ 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYA-KKEYDWTQKAPEYDN 222
Cdd:NF041364 119 GFRPDLEALRSLITPRTRAIVINSPNNPTGAVMTEAELEAILEiasRHGLIVLADEHYrfLPYDdGKHVSPSLYPGLSER 198
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   223 VIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK--PIFSLTRLSQVCAITALRDREffERCVRDGIKS----REMLYN 296
Cdd:NF041364 199 VIALGSFSKTYGMTGLRVGWLIGPKELIGAILKFKdyTTHCAPSISQYAALEALEQGP--QERVKGWVREnvrrRDALVE 276
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230   297 GLKKFKDIKVYPSEANYLLVELK-TMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSIGtfEEVERFLKILEEI 371
Cdd:NF041364 277 RLERLIGWVCEPEGGFYAFPKLKdGLPSAAFAEELLeKAGVVVLPGSAFGRPGEGYFRIGFA--NSPTRLKEALERL 351
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
37-372 2.96e-40

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 145.96  E-value: 2.96e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    37 PEDIIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGADEIIDTIFRTFVDDGD 116
Cdd:PRK09105  42 AEGAVFLNANECPLGPSPAARDAAARSAALSGRYDLELEDDLRTLFAAQEGLPADHVMAYA-GSSEPLNYAVLAFTSPTA 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   117 EVIIPIPTFTQYRVSATIHNAKIkyAKYDKEKDFKLNVESVLNNITDkTKVIFLCTPNNPTGNIIENRDVERVINE--TD 194
Cdd:PRK09105 121 GLVTADPTYEAGWRAADAQGAPV--AKVPLRADGAHDVKAMLAADPN-AGLIYICNPNNPTGTVTPRADIEWLLANkpAG 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   195 ALVVIDHAYIEYAKkEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVAN----KKIIDYMMRVKPIFSLTrlsqvCA 270
Cdd:PRK09105 198 SVLLVDEAYIHFSD-APSVVDLVAQRKDLIVLRTFSKLYGMAGMRLGLAAARpdllAKLARFGHNPLPVPAAA-----AG 271
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   271 ITALRDREFFERCVRDGIKSREMLYNGLKKfKDIKVYPSEANYLLVELKTmKAKEFCEELLKRGVIV-RDCTSFdglgDN 349
Cdd:PRK09105 272 LASLRDPKLVPQRRAENAAVREDTIAWLKK-KGYKCTPSQANCFMVDVKR-PAKAVADAMAKQGVFIgRSWPIW----PN 345
                        330       340
                 ....*....|....*....|...
gi 3122230   350 YVRVSIGTFEEVERFLKILEEII 372
Cdd:PRK09105 346 WVRVTVGSEEEMAAFRSAFAKVM 368
PRK08354 PRK08354
putative aminotransferase; Provisional
34-371 1.02e-38

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 140.25  E-value: 1.02e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    34 GIKPEDIIKLGSNENPWGPS--PKIKEKILDEIDKIHQYPEpvnpiLMKELSKFLNvdEENIIVGGdgADEIIDTIFRTF 111
Cdd:PRK08354   4 GIREEGLIDFSASVNPYPPEwlDEMFERAKEISGRYTYYEW-----LEEEFSKLFG--EPIVITAG--ITEALYLIGILA 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   112 VDDGdEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKdfklnvesvLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN 191
Cdd:PRK08354  75 LRDR-KVIIPRHTYGEYERVARFFAARIIKGPNDPEK---------LEELVERNSVVFFCNPNNPDGKFYNFKELKPLLD 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   192 ---ETDALVVIDHAYIEYAKKeydwtQKAPEYDNVIVLRTFSKVFGLAGMRVGYgvankkIIDYmmrvKPIFSLTRLSQv 268
Cdd:PRK08354 145 aveDRNALLILDEAFIDFVKK-----PESPEGENIIKLRTFTKSYGLPGIRVGY------VKGF----EEAFRSVRMPW- 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   269 cAITALrDREFFERCVRDGI----KSREMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTSFd 344
Cdd:PRK08354 209 -SIGST-GYAFLEFLIEDDFehlrKTMPLIWREKERFEKALYVKSDANFFIKDVG--DAEKFVEFLKRNGILVRDCTSF- 283
                        330       340
                 ....*....|....*....|....*..
gi 3122230   345 GLgDNYVRVSIGTFEEVERFLKILEEI 371
Cdd:PRK08354 284 GL-PGYIRFSVRDREENEKLIRALREW 309
PRK05764 PRK05764
aspartate aminotransferase; Provisional
86-370 1.06e-38

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 142.19  E-value: 1.06e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    86 LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKT 165
Cdd:PRK05764  87 LDYDPSQVIVTT-GAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGEENGFKLTVEQLEAAITPKT 165
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   166 KVIFLCTPNNPTGNIIENRDVE---RVINETDALVVIDHAY--IEYAKKEYDW-TQKAPE-YDNVIVLRTFSKVFGLAGM 238
Cdd:PRK05764 166 KALILNSPSNPTGAVYSPEELEaiaDVAVEHDIWVLSDEIYekLVYDGAEFTSiASLSPElRDRTITVNGFSKAYAMTGW 245
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   239 RVGYGVANKKIIDYMMRVKP-IFS-LTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFKDIKVYPSE-ANYL 314
Cdd:PRK05764 246 RLGYAAGPKELIKAMSKLQShSTSnPTSIAQYAAVAALNgPQDEVEEMRQAFEERRDLMVDGLNEIPGLECPKPEgAFYV 325
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3122230   315 ------LVELKTMKAKEFCEELLKR-GVIVRDCTSFdGLgDNYVRVSIGTFEE-----VERFLKILEE 370
Cdd:PRK05764 326 fpnvskLLGKSITDSLEFAEALLEEaGVAVVPGIAF-GA-PGYVRLSYATSLEdleegLERIERFLES 391
PRK08153 PRK08153
pyridoxal phosphate-dependent aminotransferase;
21-372 4.25e-37

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181255  Cd Length: 369  Bit Score: 137.44  E-value: 4.25e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    21 VPGKSKEEIARAYGIKPEdiIKLGSNENPWGPSPKIKEKILDEIDKIHQYPEPVNPILMKELSKFLNVDEENIIVGGdGA 100
Cdd:PRK08153  17 VPFVGPETLERQRGRPFR--ARIGANESGFGPSPSVIAAMREAAAEIWKYGDPENHDLRHALAAHHGVAPENIMVGE-GI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   101 DEIIDTIFRTFVDDGDEVIIPI---PTFTqYRVSA---TIHnaKIKYAKyDKEkdfklNVESVLNNIT-DKTKVIFLCTP 173
Cdd:PRK08153  94 DGLLGLIVRLYVEPGDPVVTSLgayPTFN-YHVAGfggRLV--TVPYRD-DRE-----DLDALLDAARrENAPLVYLANP 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   174 NNPTGNIIENRDVERVIN---ETdALVVIDHAYIEYAKKEydwtqKAPEYD----NVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PRK08153 165 DNPMGSWHPAADIVAFIEalpET-TLLVLDEAYCETAPAG-----AAPPIDtddpNVIRMRTFSKAYGLAGARVGYAIGA 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   247 KKIIDYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGIKSREML-----YNGLKKFkdikvyPSEANYLLVELKTM 321
Cdd:PRK08153 239 PGTIKAFDKVRNHFGMNRIAQAAALAALKDQAYLAEVVGKIAAARDRIaaiarANGLTPL------PSATNFVAIDCGRD 312
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 3122230   322 K--AKEFCEELLKRGVIVRdcTSFDGLGDNYVRVSIGTFEEVERFLKILEEII 372
Cdd:PRK08153 313 GafARAVLDGLIARDIFVR--MPGVAPLDRCIRVSCGPDEELDLFAEALPEAL 363
PRK08361 PRK08361
aspartate aminotransferase; Provisional
36-371 1.83e-36

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 136.16  E-value: 1.83e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    36 KPEDIIKLGSNENPWGPSPKIKEKILDEIDK--IHQYPEPVNPILMKELSKF------LNVDEENIIVGGdGADEIIDTI 107
Cdd:PRK08361  31 KMENVISLGIGEPDFDTPKNIKEAAKRALDEgwTHYTPNAGIPELREAIAEYykkfygVDVDVDNVIVTA-GAYEATYLA 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   108 FRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---R 184
Cdd:PRK08361 110 FESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREENEFQPDPDELLELITKRTRMIVINYPNNPTGATLDKevaK 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   185 DVERVINETDALVVIDHAYIEY---AKKEYDWTQKAPeyDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--I 259
Cdd:PRK08361 190 AIADIAEDYNIYILSDEPYEHFlyeGAKHYPMIKYAP--DNTILANSFSKTFAMTGWRLGFVIAPEQVIKDMIKLHAyiI 267
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   260 FSLTRLSQVCAITALRDREFF---ERCVRDGIKSREMLYNGLKKFKDIKVY-PSEANYLLVELKT--MKAKEFCEELL-K 332
Cdd:PRK08361 268 GNVASFVQIAGIEALRSKESWkavEEMRKEYNERRKLVLKRLKEMPHIKVFePKGAFYVFANIDEtgMSSEDFAEWLLeK 347
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 3122230   333 RGVIVRDCTSFDGLGDNYVRVSIGT-----FEEVERFLKILEEI 371
Cdd:PRK08361 348 ARVVVIPGTAFGKAGEGYIRISYATskeklIEAMERMEKALEEL 391
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
33-372 1.99e-36

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 136.04  E-value: 1.99e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    33 YGIKPEDIIKLGSNENPWGPSPKIKEKILDEIDK--IHQYPEPVN-PILMKELSKFLNVDEENIIVGgDGADEIIDTIFR 109
Cdd:PRK06225  23 YVFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEgeYCKYPPPEGfPELRELILKDLGLDDDEALIT-AGATESLYLVMR 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAK-YDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE- 187
Cdd:PRK06225 102 AFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPiYSEECNYKLTPELVKENMDENTRLIYLIDPLNPLGSSYTEEEIKe 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   188 --RVINETDALVVIDHAYIEYAKKEYDWTQKAPEydNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYM-MRVKPIFSLTR 264
Cdd:PRK06225 182 faEIARDNDAFLLHDCTYRDFAREHTLAAEYAPE--HTVTSYSFSKIFGMAGLRIGAVVATPDLIEVVkSIVINDLGTNV 259
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   265 LSQVCAITALRDR-EFFERCVRDGIKSREMLYNGLKKFKDIK--VYPSEANYLLVELKT--MKAKEFCEELLKRGVIVRD 339
Cdd:PRK06225 260 IAQEAAIAGLKVKdEWIDRIRRTTFKNQKLIKEAVDEIEGVFlpVYPSHGNMMVIDISEagIDPEDLVEYLLERKIFVRQ 339
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 3122230   340 CTSFDGL-GDNYVRV--SIGTfEEVERFLKILEEII 372
Cdd:PRK06225 340 GTYTSKRfGDRYIRVsfSIPR-EQVEVFCEEFPDVV 374
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
110-354 7.86e-32

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 123.68  E-value: 7.86e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---RDV 186
Cdd:PRK06348 108 SILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDGFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKetlEEI 187
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   187 ERVINETDALVVIDHAYIEYAKKE--YDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--IFSL 262
Cdd:PRK06348 188 AKIAIEYDLFIISDEVYDGFSFYEdfVPMATLAGMPERTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEgiCFSA 267
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   263 TRLSQVCAITALRDREFFERCVRDGIKSR-EMLYNGLKKFKDIKVYPSEAN-YLLVELKT--MKAKEFCEELLKRG-VIV 337
Cdd:PRK06348 268 PTISQRAAIYALKHRDTIVPLIKEEFQKRlEYAYKRIESIPNLSLHPPKGSiYAFINIKKtgLSSVEFCEKLLKEAhVLV 347
                        250
                 ....*....|....*..
gi 3122230   338 RDCTSFDGLGDNYVRVS 354
Cdd:PRK06348 348 IPGKAFGESGEGYIRLA 364
PRK07682 PRK07682
aminotransferase;
78-369 1.14e-30

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 120.22  E-value: 1.14e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    78 LMKELSKFLN------VDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFK 151
Cdd:PRK07682  62 LRQEIAKYLKkrfavsYDPNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLENEFK 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   152 LNVESVLNNITDKTKVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVL 226
Cdd:PRK07682 142 VQPAQIEAAITAKTKAILLCSPNNPTGAVLnksELEEIAVIVEKHDLIVLSDEIYAEltYDEAYTSFASIKGMRERTILI 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   227 RTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPiFSLT---RLSQVCAITALRD-REFFERcVRDGIKSREMLYngLKKFK 302
Cdd:PRK07682 222 SGFSKGFAMTGWRLGFIAAPVYFSEAMLKIHQ-YSMMcapTMAQFAALEALRAgNDDVIR-MRDSYRKRRNFF--VTSFN 297
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   303 DIKV---YPSEANYLLVELKT--MKAKEFCEELLK-RGVIVRDCTSFDGLGDNYVRVSIGT--------FEEVERFLKIL 368
Cdd:PRK07682 298 EIGLtchVPGGAFYAFPSISStgLSSEEFAEQLLLeEKVAVVPGSVFGESGEGFIRCSYATsleqlqeaMKRMKRFVENK 377

                 .
gi 3122230   369 E 369
Cdd:PRK07682 378 K 378
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
48-354 2.10e-29

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 116.83  E-value: 2.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    48 NPWGPSPK-----IKEKILDEIDKIHQY-PEPVNPILMKELSKFLN------VDEENII--VGGDGAdeiIDTIFRTFVD 113
Cdd:PRK06836  42 NPSVPPPAavkeaLRELAEEEDPGLHGYmPNAGYPEVREAIAESLNrrfgtpLTADHIVmtCGAAGA---LNVALKAILN 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   114 DGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDkEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI--- 190
Cdd:PRK06836 119 PGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTD-TDTFQPDLDALEAAITPKTKAVIINSPNNPTGVVYSEETLKALAall 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   191 ------NETDALVVIDHAYIEYAkkeYDWTQKA---PEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYmMRVKPIFS 261
Cdd:PRK06836 198 eekskeYGRPIYLISDEPYREIV---YDGAEVPyifKYYDNSIVVYSFSKSLSLPGERIGYIAVNPEMEDA-DDLVAALV 273
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   262 LT-R-LSQVCAiTALRDReFFERCVRDGI------KSREMLYNGLKKFKDIKVYPSEANYLLVELKTMKAKEFCEELLKR 333
Cdd:PRK06836 274 FAnRiLGFVNA-PALMQR-VVAKCLDATVdvsiykRNRDLLYDGLTELGFECVKPQGAFYLFPKSPEEDDVAFCEKAKKH 351
                        330       340
                 ....*....|....*....|.
gi 3122230   334 GVIVRDCTSFDGLGdnYVRVS 354
Cdd:PRK06836 352 NLLLVPGSGFGCPG--YFRLS 370
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
9-371 1.13e-28

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 115.01  E-value: 1.13e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     9 KVRDVVKKLKPYVPG---KSKEEiARAYGikpEDIIKLGSNEnPWGPSPK-IKEKILDEIDKI--HQYPEPVN-PILMKE 81
Cdd:PRK09276   3 KLADRIKNLPPYLFAeidKKKAE-KIARG---VDVISLGIGD-PDLPTPDhIIEAMCKAVEDPenHQYPSYEGmLEFRKA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    82 LSKF------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVE 155
Cdd:PRK09276  78 VADWykrrfgVELDPETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLKEENGFLPDLD 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   156 SVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEYdwtqKAPEYDNV-------IV 225
Cdd:PRK09276 158 AIPEDVAKKAKLMFINYPNNPTGAVADLEFFEEVVDfakKYDIIVCHDAAYSEIAYDGY----KPPSFLEVpgakdvgIE 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   226 LRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-----IFSLTrlsQVCAITALR-DREFFERCVRDGIKSREMLYNGLK 299
Cdd:PRK09276 234 FHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKSnvdsgVFQAI---QEAGIAALNgPQEVVEELRKIYQERRDILVEGLR 310
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230   300 KFkDIKVYPSEAN-YLLVEL-KTMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSIGTfeEVERFLKILEEI 371
Cdd:PRK09276 311 KL-GLEVEPPKATfYVWAPVpKGYTSAEFATLLLdKAGVVVTPGNGFGEYGEGYFRIALTV--PDERIEEAVERI 382
PRK07683 PRK07683
aminotransferase A; Validated
86-366 2.75e-28

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 113.67  E-value: 2.75e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    86 LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKyDKEKDFKLNVESVLNNITDKT 165
Cdd:PRK07683  84 LHYSPESEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFID-TRSTGFRLTAEALENAITEKT 162
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   166 KVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK07683 163 RCVVLPYPSNPTGVTLskeELQDIADVLKDKNIFVLSDEIYSElvYEQPHTSIAHFPEMREKTIVINGLSKSHSMTGWRI 242
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   241 GYGVANKKIIDYMMRVKP--IFSLTRLSQVCAITALRDREFFERCVRDGIKSR-EMLYNGLKKFKDIKVYPSEANYLLVE 317
Cdd:PRK07683 243 GFLFAPSYLAKHILKVHQynVTCASSISQYAALEALTAGKDDAKMMRHQYKKRrDYVYNRLISMGLDVEKPTGAFYLFPS 322
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   318 LK--TMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVS----IGTFEE----VERFLK 366
Cdd:PRK07683 323 IGhfTMSSFDFALDLVEEaGLAVVPGSAFSEYGEGYVRLSyaysIETLKEgldrLEAFLQ 382
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
5-370 1.67e-26

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 109.17  E-value: 1.67e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     5 MIENKVRDV----VKKLKPYVpgkskeEIARAYGIKpedIIKLgsneNPWGPSPKIKEKILDEIDKIHqyPEPV------ 74
Cdd:PRK07568   2 KISKRVLNMpaspIRKLVPYA------DEAKKRGIK---VYHL----NIGQPDIKTPEVFFEAIKNYD--EEVLayshsq 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    75 -NPILMKELSKF-----LNVDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEK 148
Cdd:PRK07568  67 gIPELREAFAKYykkwgIDVEPDEILITN-GGSEAILFAMMAICDPGDEILVPEPFYANYNGFATSAGVKIVPVTTKIEE 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   149 DFKL-NVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAkkeYDwtqkAPEY---- 220
Cdd:PRK07568 146 GFHLpSKEEIEKLITPKTKAILISNPGNPTGVVYTKEELEMLAEiakKHDLFLISDEVYREFV---YD----GLKYtsal 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   221 ------DNVIVLRTFSKVFGLAGMRVGYGVA-NKKIIDYMMRvkpiFSLTRLS-----QVCAITALR-DREFFERCVRDG 287
Cdd:PRK07568 219 slegleDRVIIIDSVSKRYSACGARIGCLISkNKELIAAAMK----LCQARLSpptleQIGAAALLDtPESYFDEVREEY 294
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   288 IKSREMLYNGLKKFKDIKVY-PSEANYLLVELKTMKAKEFCEELLK------RGVIVRDCTSF---DGLGDNYVRVS-IG 356
Cdd:PRK07568 295 KKRRDILYEELNKIPGVVCEkPKGAFYIIAKLPVDDAEDFAKWLLTdfnyngETVMVAPASGFyatPGLGKNEIRIAyVL 374
                        410
                 ....*....|....
gi 3122230   357 TFEEVERFLKILEE 370
Cdd:PRK07568 375 NEEDLKRAMEILKE 388
PRK08363 PRK08363
alanine aminotransferase; Validated
6-366 4.97e-23

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 99.11  E-value: 4.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     6 IENKVRDVVkklkpyVPGKSKEEiaraygiKPEDIIKLGSNEnP----WGPSPKIKEKILDEIDKIHQY-------PEPV 74
Cdd:PRK08363  11 VEYAIRDVV------LPARELEK-------KGIKVIRLNIGD-PvkfdFQPPEHMKEAYCRAIKEGHNYygpseglPELR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    75 NPILMKELSKF-LNVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLN 153
Cdd:PRK08363  77 EAIVKREKRKNgVDITPDDVRVT-AAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEYRTIEEEGWQPD 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   154 VESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYDWTQKAPEyDNVIVLRT 228
Cdd:PRK08363 156 IDDIRKKITEKTKAIAVINPNNPTGALYEKKTLKEILDiagEHDLPVISDEIYdlMTYEGKHVSPGSLTKD-VPVIVMNG 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   229 FSKVFGLAGMRVGY--GVANKKIIDYMMRVKPIFSLTRLS-----QVCAITALRD-REFFERCVRDGIKSREMLYNGLKK 300
Cdd:PRK08363 235 LSKVYFATGWRLGYiyFVDPEGKLAEVREAIDKLARIRLCpntpaQFAAIAGLTGpMDYLEEYMKKLKERRDYIYKRLNE 314
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 3122230   301 FKDIK-VYPSEANYL---LVELKTMKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRV----SIGTFEE----VERFLK 366
Cdd:PRK08363 315 IPGIStTKPQGAFYIfprIEEGPWKDDKEFVLDVLhEAHVLFVHGSGFGEYGAGHFRLvflpPVEILEEamdrFEEFMR 393
PRK07324 PRK07324
transaminase; Validated
87-370 1.30e-22

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 97.70  E-value: 1.30e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    87 NVDEENIIV--GGDGADEIIdtiFRTFVDDGDEVIIPIPTFTQ-YRVSATIhNAKIKYAKYDKEKDFKLNVESVLNNITD 163
Cdd:PRK07324  77 NVKPENILQtnGATGANFLV---LYALVEPGDHVISVYPTYQQlYDIPESL-GAEVDYWQLKEENGWLPDLDELRRLVRP 152
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   164 KTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEyDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK07324 153 NTKLICINNANNPTGALMDRAYLEEIVEiarSVDAYVLSDEVYRPLDEDG-STPSIADLYEKGISTNSMSKTYSLPGIRV 231
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   241 GYGVANKKII-------DYMMrvkpiFSLTRLSQVCAITALRDRE-FFERcvrdgikSREMLYNGLKKFKD-IK------ 305
Cdd:PRK07324 232 GWIAANEEVIdilrkyrDYTM-----ICAGVFDDMLASLALEHRDaILER-------NRKIVRTNLAILDEwVAkeprvs 299
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 3122230   306 -VYPSEANYLLVELKT-MKAKEFCEELLKR-GVIVRDCTSFDglGDNYVRVSIGTFEEV-ERFLKILEE 370
Cdd:PRK07324 300 yVKPKAVSTSFVKLDVdMPSEDFCLKLLKEtGVLLVPGNRFD--LEGHVRIGYCCDTETlKKGLKKLSE 366
PLN00175 PLN00175
aminotransferase family protein; Provisional
86-363 6.00e-21

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 93.39  E-value: 6.00e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    86 LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYdKEKDFKLNVESVLNNITDKT 165
Cdd:PLN00175 110 LVVDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTL-RPPDFAVPEDELKAAFTSKT 188
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   166 KVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAkKEYDWTQKAP---EYDNVIVLRTFSKVFGLAGMR 239
Cdd:PLN00175 189 RAILINTPHNPTGKMFTREELELIASlckENDVLAFTDEVYDKLA-FEGDHISMASlpgMYERTVTMNSLGKTFSLTGWK 267
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   240 VGYGVANKKIIdYMMRVKP---IFSLTRLSQVCAITALRDRE-FFERCVRDGIKSREMLYNGLKKFkDIKVYPSEANYLL 315
Cdd:PLN00175 268 IGWAIAPPHLT-WGVRQAHsflTFATATPMQWAAVAALRAPEsYYEELKRDYSAKKDILVEGLKEV-GFKVYPSSGTYFV 345
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 3122230   316 VELKTMKAKE----FCEELLKRGVIVRDCTSFDGL----GDNYVRVSIGTFEEVER 363
Cdd:PLN00175 346 MVDHTPFGFEndiaFCEYLIEEVGVAAIPPSVFYLnpedGKNLVRFAFCKDEETLR 401
PRK08175 PRK08175
aminotransferase; Validated
14-355 3.25e-20

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 90.93  E-value: 3.25e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    14 VKKLKPYV---PGKSKEEiARAYGikpEDIIKLGSNeNPWGPSPK-IKEKILDEIDK--IHQYPEPVN-PILMKELSKF- 85
Cdd:PRK08175   6 IDRLPPYVfniTAELKMA-ARRRG---EDIIDFSMG-NPDGPTPPhIVEKLCEVAQRpdTHGYSTSRGiPRLRRAISRWy 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    86 -----LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNN 160
Cdd:PRK08175  81 qdrydVDIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   161 ITDKTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIEYAKKEYdwtqKAPEY-------DNVIVLRTFS 230
Cdd:PRK08175 161 SYPKPKMMILGFPSNPTAQCVELEFFEKVVAlakRYDVLVVHDLAYADIVYDGW----KAPSImqvpgakDVAVEFFTLS 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   231 KVFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALrdrEFFERCVRDGI----KSREMLYNG 297
Cdd:PRK08175 237 KSYNMAGWRIGFMVGNPELVSALARIKsyhdygtftPL-------QVAAIAAL---EGDQQCVRDIAeqykRRRDVLVKG 306
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230   298 LKKFKDIKVYPSEANYLLVEL----KTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSI 355
Cdd:PRK08175 307 LHEAGWMVEMPKASMYVWAKIpepyAAMGSLEFAKKLLNEaKVCVSPGIGFGDYGDTHVRFAL 369
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
41-372 7.06e-20

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 90.13  E-value: 7.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    41 IKLGSNENPWGPSPKIKEKILDEID--KIHQYpEPVNPI------LMKELSKF--LNVDEENIIVGGDGADEIIDTIFRT 110
Cdd:PRK05957  30 ISLGQGVVSYPPPPEAIEALNNFLAnpENHKY-QAVQGIpplleaITQKLQQDngIELNNEQAIVVTAGSNMAFMNAILA 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKekDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---RDVE 187
Cdd:PRK05957 109 ITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDD--NYQLQPEAIEQAITPKTRAIVTISPNNPTGVVYPEallRAVN 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   188 RVINETDALVVIDHAYiEYAKkeYD----WTQKA-PEYDN-VIVLRTFSKVFGLAGMRVGYGV-------ANKKIIDYMM 254
Cdd:PRK05957 187 QICAEHGIYHISDEAY-EYFT--YDgvkhFSPGSiPGSGNhTISLYSLSKAYGFASWRIGYMVipihlleAIKKIQDTIL 263
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   255 RVKPIFsltrlSQVCAITALRD-REFFERCVRDGIKSREMLYNGLKKFKDIK--VYPSEANYLLVELKT-MKAKEFCEEL 330
Cdd:PRK05957 264 ICPPVV-----SQYAALGALQVgKSYCQQHLPEIAQVRQILLKSLGQLQDRCtlHPANGAFYCFLKVNTdLNDFELVKQL 338
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 3122230   331 LKR-GVIVRDCTSFdGLGDN-YVRVSIGTFEE------VERFLKILEEII 372
Cdd:PRK05957 339 IREyRVAVIPGTTF-GMKNGcYLRIAYGALQKatakegIERLVQGLKTIV 387
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
111-363 1.75e-19

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 89.09  E-value: 1.75e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI 190
Cdd:PRK07681 113 YANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVI 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   191 ---NETDALVVIDHAYIEYAkkeYDwTQKAPEYDNV-------IVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK--- 257
Cdd:PRK07681 193 afaKKHNIIVVHDFAYAEFY---FD-GNKPISFLSVpgakevgVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKsnt 268
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   258 ------PIfsltrlsQVCAITALR--------DREFFErcvrdgiKSREMLYNGLKKFKDIKVYPSEANYLLVEL-KTMK 322
Cdd:PRK07681 269 dygvflPI-------QKAACAALRngaafcekNRGIYQ-------ERRDTLVDGFRTFGWNVDKPAGSMFVWAEIpKGWT 334
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 3122230   323 AKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSIGTFEEVER 363
Cdd:PRK07681 335 SLSFAYALMDRaNVVVTPGHAFGPHGEGFVRIALVQDEEVLQ 376
PRK07908 PRK07908
threonine-phosphate decarboxylase;
173-373 5.31e-19

threonine-phosphate decarboxylase;


Pssm-ID: 236128  Cd Length: 349  Bit Score: 86.98  E-value: 5.31e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   173 PNNPTGnIIENRDVERVINETDALVVIDHAYIeyakkeyDWTQKAPE------YDNVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PRK07908 148 PTNPTS-VLHPAEQLLALRRPGRILVVDEAFA-------DAVPGEPEslagddLPGVLVLRSLTKTWSLAGLRVGYALGA 219
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   247 KKIIDYMMRVKPIFS-----LTRLSQVCAITALRD-REFFERCVRDgiksREMLYNGLKKFKDIKVYPSEANYLLVELKt 320
Cdd:PRK07908 220 PDVLARLTRGRAHWPvgtlqLEAIAACCAPRAVAEaAADAARLAAD----RAEMVAGLRAVGARVVDPAAAPFVLVRVP- 294
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 3122230   321 mKAKEFCEELLKRGVIVRDCTSFDGLGDNYVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK07908 295 -DAELLRKRLRERGIAVRRGDTFPGLDPDYLRLAVRPRAEVPVLVQALAEILK 346
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
69-373 2.79e-18

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 86.04  E-value: 2.79e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   69 QYPEPV-NPILMKELSKFLN-----VDEENIIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYA 142
Cdd:COG1167 143 GYGDPQgLPELREAIARYLArrgvpASPDQILITS-GAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPV 221
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  143 KYDKEKdfkLNVESVLNNITD-KTKVIFLcTPN--NPTGNI--IENRdvERVIN---ETDALVVIDHAYIEYAkkeYDwt 214
Cdd:COG1167 222 PVDEDG---LDLDALEAALRRhRPRAVYV-TPShqNPTGATmsLERR--RALLElarRHGVPIIEDDYDSELR---YD-- 290
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  215 QKAP-------EYDNVIVLRTFSKVFGlAGMRVGYGVANKKIIDYMMRVKPIFSLT--RLSQvcAITA--LRDREfFERC 283
Cdd:COG1167 291 GRPPpplaaldAPGRVIYIGSFSKTLA-PGLRLGYLVAPGRLIERLARLKRATDLGtsPLTQ--LALAefLESGH-YDRH 366
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  284 VRdGIKS-----REMLYNGLKKF--KDIKVYPSEA-NYLLVEL-KTMKAKEFCEELLKRGVIVRDCTSF--DGLGDNYVR 352
Cdd:COG1167 367 LR-RLRReyrarRDLLLAALARHlpDGLRVTGPPGgLHLWLELpEGVDAEALAAAALARGILVAPGSAFsaDGPPRNGLR 445
                       330       340
                ....*....|....*....|...
gi 3122230  353 VSIGTF--EEVERFLKILEEIIS 373
Cdd:COG1167 446 LGFGAPseEELEEALRRLAELLR 468
PRK05942 PRK05942
aspartate aminotransferase; Provisional
3-355 3.50e-17

aspartate aminotransferase; Provisional


Pssm-ID: 180317  Cd Length: 394  Bit Score: 82.07  E-value: 3.50e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     3 DWMienKVRDVVKKLKPYVPGKSKEEIARA--YGIkpeDIIKLGSNeNPWGPSPK-IKEKILDEID--KIHQYP------ 71
Cdd:PRK05942   4 DWI---TPADRLQALPPYVFARLDELKARAreQGL---DLIDLGMG-NPDGAAPQpVIEAAIAALAdpQNHGYPpfegta 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    72 ---EPVNPILMKELSKFLNVDEENIIVggDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEK 148
Cdd:PRK05942  77 sfrQAITDWYHRRYGVELDPDSEALPL--LGSKEGLTHLALAYVNPGDVVLVPSPAYPAHFRGPLIAGAQIYPIILKPEN 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAKKEYDWTQ--KAPEYDNV 223
Cdd:PRK05942 155 DWLIDLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVafaRKYEIMLVHDLCYAELAFDGYQPTSllEIPGAKDI 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   224 IV-LRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-----IFSLTrlsQVCAITALRDREFFERCVRDGIKS-REMLYN 296
Cdd:PRK05942 235 GVeFHTLSKTYNMAGWRVGFVVGNRHIIQGLRTLKTnldygIFSAL---QKAAETALQLPDSYLQQVQERYRTrRDFLIQ 311
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 3122230   297 GLKKFkDIKVYPSEAN-YLLVELKT-MKAKEFCEELL-KRGVIVRDCTSFDGLGDNYVRVSI 355
Cdd:PRK05942 312 GLGEL-GWNIPPTKATmYLWVPCPVgMGSTDFALNVLqKTGVVVTPGNAFGEGGEGYVRISL 372
PRK06425 PRK06425
histidinol-phosphate aminotransferase; Validated
32-373 1.19e-16

histidinol-phosphate aminotransferase; Validated


Pssm-ID: 102370  Cd Length: 332  Bit Score: 79.90  E-value: 1.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    32 AYGIKPEDIIKLGSNENPWgpspkikekilDEIDKIHQYPEpVNPILMKELSKFLNVDEENIIVGGDGADEIIDTIFrTF 111
Cdd:PRK06425  10 EASSKYGRIIDFSANINDF-----------MDIGDISIYPE-ISYTDIEDQIKIYTQGLKIKVLIGPGLTHFIYRLL-SY 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   112 VDDGDEVIIpIPTFTQYRVSATIHNAKIKYAKYDKEKdfklNVESVLNNItdKTKVIFLCTPNNPTGNIIENRDVERVIN 191
Cdd:PRK06425  77 INVGNIIIV-EPNFNEYKGYAFTHGIRISALPFNLIN----NNPEILNNY--NFDLIFIVSPDNPLGNLISRDSLLTISE 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   192 ETD---ALVVIDHAYIEYAKKEYDWT-QKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSltrlsq 267
Cdd:PRK06425 150 ICRkkgALLFIDEAFIDFVPNRAEEDvLLNRSYGNVIIGRSLTKILGIPSLRIGYIATDDYNMKISRKITEPWS------ 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   268 VC--AITALRD---REFFERCVRDGIKSREMLYNGLKKFKDIKVYPSEANYLLVELKtmKAKEFCEELLKRGVIVRDCTS 342
Cdd:PRK06425 224 VCdpAIDFIRSidlDYVAKHSLDIMENERSYLINNLEAMGFRAAGDPSANFITFMIP--DAHDFYSYLLKNGILVRLLDD 301
                        330       340       350
                 ....*....|....*....|....*....|.
gi 3122230   343 FDGLGDNYVRVSIGTFEEVERFLKILEEIIS 373
Cdd:PRK06425 302 YECLGEQYIRIAIRRRSFNIKLVNALRNFLN 332
PRK06107 PRK06107
aspartate transaminase;
93-361 8.47e-16

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 78.24  E-value: 8.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    93 IIVGGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCT 172
Cdd:PRK06107  96 ITVGG-GAKQAIFLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPEEQGFKLTPEALEAAITPRTRWLILNA 174
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   173 PNNPTGNII---ENRDVERVINE-TDALVVIDHAYIEYAKKEYDWT---QKAPEY-DNVIVLRTFSKVFGLAGMRVGYGV 244
Cdd:PRK06107 175 PSNPTGAVYsraELRALADVLLRhPHVLVLTDDIYDHIRFDDEPTPhllAAAPELrDRVLVTNGVSKTYAMTGWRIGYAA 254
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   245 ANKKIIDYMMRVKPIFS--LTRLSQVCAITALR-DREFFERCVRDGIKSREMLYNGLKKFKDIK-VYPSEANYLLV---- 316
Cdd:PRK06107 255 GPADLIAAINKLQSQSSscPSSISQAAAAAALNgDQSFVTESVAVYKQRRDYALALLNAIPGLScLVPDGAFYLYVncag 334
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 3122230   317 -------ELKTMKA-KEFCEELLKR-GVIVRDCTSFdGLGDnYVRVSIGTFEEV 361
Cdd:PRK06107 335 ligkttpEGKVLETdQDVVLYLLDSaGVAVVQGTAY-GLSP-YFRLSIATSLET 386
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
8-369 8.80e-16

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 78.15  E-value: 8.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230      8 NKVRDVVKKLKPYvPGKSKEeiaraygikpedIIKLGSNENPWGPS----PKIKEKILDEIDKiHQY----PEPVNPILM 79
Cdd:TIGR01265  14 NPIRAIVDNLKVK-PNPEKP------------VIPLSHGDPSVFGNlrtdPEAEEAVKDALRS-GKFngyaPSVGALAAR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     80 KELSKFLNVDEENIIVGGD-----GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNV 154
Cdd:TIGR01265  80 EAVAEYLSSDLPGKLTADDvvltsGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSGLEVRLYDLLPEKDWEIDL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    155 ESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY--IEYAKKEY----DWTQKAPeydnVIV 225
Cdd:TIGR01265 160 DGLESLADEKTVAIVVINPSNPCGSVFSRDHLQKIAevaEKLGIPIIADEIYghMVFGDAPFipmaSFASIVP----VLS 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    226 LRTFSKVFGLAGMRVGY-------GVANKKIIDymmrvkpifSLTRLSQV----CAIT--ALRD------REFFERcVRD 286
Cdd:TIGR01265 236 LGGISKRWVVPGWRLGWiiihdphGIFRDTVLQ---------GLKNLLQRilgpATIVqgALPDilentpQEFFDG-KIS 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    287 GIKSREML-YNGLKKFKDIK-VYPSEANYLLVELKTMKAKE------FCEELLK-RGVIVRDCTSFdGLgDNYVRVSIGT 357
Cdd:TIGR01265 306 VLKSNAELcYEELKDIPGLVcPKPEGAMYLMVKLELELFPEikddvdFCEKLAReESVICLPGSAF-GL-PNWVRITITV 383
                         410
                  ....*....|....
gi 3122230    358 FEEV--ERFLKILE 369
Cdd:TIGR01265 384 PESMleEACSRIKE 397
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
88-314 1.78e-15

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 76.91  E-value: 1.78e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    88 VDEENIIVGGDGADEIIDTIfRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKD-FKLNVESVLNNITDKTK 166
Cdd:PRK06108  82 TPPERIAVTSSGVQALMLAA-QALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGGGgWTLDLDRLLAAITPRTR 160
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   167 VIFLCTPNNPTGNIIeNRDVERVI----NETDALVVIDHAYIEYAkkeYDWTQKAPEY-------DNVIVLRTFSKVFGL 235
Cdd:PRK06108 161 ALFINSPNNPTGWTA-SRDDLRAIlahcRRHGLWIVADEVYERLY---YAPGGRAPSFldiaepdDRIIFVNSFSKNWAM 236
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   236 AGMRVGYGVAN-------KKIIDYMMRVKPIFsltrlSQVCAITALRDRE-FFERCVRDGIKSREMLYNGLKKFKDIKVY 307
Cdd:PRK06108 237 TGWRLGWLVAPpalgqvlEKLIEYNTSCVAQF-----VQRAAVAALDEGEdFVAELVARLRRSRDHLVDALRALPGVEVA 311

                 ....*...
gi 3122230   308 PSE-ANYL 314
Cdd:PRK06108 312 KPDgAMYA 319
PRK08068 PRK08068
transaminase; Reviewed
111-360 9.74e-15

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 74.96  E-value: 9.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   111 FVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI 190
Cdd:PRK08068 114 LMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAENNFLPDYTKIPEEVAEKAKLMYLNYPNNPTGAVATKAFFEETV 193
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   191 ---NETDALVVIDHAY--IEY-AKKEYDWTQkAPEYDNV-IVLRTFSKVFGLAGMRVGYGVANKKII-------DYMMrv 256
Cdd:PRK08068 194 afaKKHNIGVVHDFAYgaIGFdGQKPVSFLQ-TPGAKDVgIELYTLSKTFNMAGWRVAFAVGNESVIeainllqDHLF-- 270
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   257 kpiFSLTRLSQVCAITALRDReffERCVRDGI----KSREMLYNGLKKFK-DIKVyPSEANYLLVEL-KTMKAKEFCEEL 330
Cdd:PRK08068 271 ---VSLFGAIQDAAIEALLSD---QSCVAELVaryeSRRNAFISACREIGwEVDA-PKGSFFAWMPVpKGYTSEQFADLL 343
                        250       260       270
                 ....*....|....*....|....*....|.
gi 3122230   331 LKR-GVIVRDCTSFDGLGDNYVRVSIGTFEE 360
Cdd:PRK08068 344 LEKaHVAVAPGNGFGEHGEGYVRVGLLTDEE 374
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
38-354 1.76e-14

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 73.99  E-value: 1.76e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    38 EDIIKLGSNENPWGPSPKIKEKILDEID--KIHQYPEPVNPILMKELSKF------LNVDEENIIVGGDGADEIIDTIFR 109
Cdd:PRK07309  30 PGILKLTLGEPDFTTPDHVKEAAKRAIDanQSHYTGMAGLLELRQAAADFvkekynLDYAPENEILVTIGATEALSASLT 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   110 TFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKyDKEKDFKLNVESVLNNIT---DKTKVIFLCTPNNPTGnIIENRD- 185
Cdd:PRK07309 110 AILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEID-TTENDFVLTPEMLEKAILeqgDKLKAVILNYPANPTG-VTYSREq 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   186 ---VERVINETDALVVIDHAYIEYAKKEYDWTQKApEY--DNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP-- 258
Cdd:PRK07309 188 ikaLADVLKKYDIFVISDEVYSELTYTGEPHVSIA-EYlpDQTILINGLSKSHAMTGWRIGLIFAPAEFTAQLIKSHQyl 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   259 IFSLTRLSQVCAITAL---RDREFFERcvRDGIKSREMLYNGLKK--FKDIKvyPSEANYLLVELKT---MKAKEFCEEL 330
Cdd:PRK07309 267 VTAATTMAQFAAVEALtngKDDALPMK--KEYIKRRDYIIEKMTDlgFKIIK--PDGAFYIFAKIPAgynQDSFKFLQDF 342
                        330       340
                 ....*....|....*....|....*
gi 3122230   331 L-KRGVIVRDCTSFDGLGDNYVRVS 354
Cdd:PRK07309 343 ArKKAVAFIPGAAFGPYGEGYVRLS 367
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
12-370 5.12e-14

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 72.81  E-value: 5.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    12 DVVKKLKPYVPGKSkEEIARAYGIKPEDIIKLgSNENPWGPSPK-IKEKILDEI--DKIHQYPepvnpiLMKELSKF--- 85
Cdd:PRK08636   8 NKIKRLPKYVFAEV-NELKMAARRAGEDIIDF-SMGNPDGPTPQhIIDKLCESAqkPKTHGYS------VSKGIYKLrla 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    86 ----------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTF---TQYRVSA--TIHNAKIKY-AKYD-KEK 148
Cdd:PRK08636  80 icnwykrkynVDLDPETEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYpihSQAFILAggNVHKMPLEYnEDFElDED 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   149 DFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAKKEYdwtqKAPEY----- 220
Cdd:PRK08636 160 QFFENLEKALRESSPKPKYVVVNFPHNPTTATVEKSFYERLValaKKERFYIISDIAYADITFDGY----KTPSIleveg 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   221 --DNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDReffERCVRDGI- 288
Cdd:PRK08636 236 akDVAVESYTLSKSYNMAGWRVGFVVGNKKLVGALKKIKswldygmftPI-------QVAATIALDGD---QSCVEEIRe 305
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   289 ---KSREMLyngLKKFKDIK---VYPSEANYLLVEL----KTMKAKEFCEELLKRG-VIVRDCTSFDGLGDNYVRVSIGT 357
Cdd:PRK08636 306 tyrKRRDVL---IESFANAGwelQKPRASMFVWAKIpepaRHLGSLEFSKQLLTEAkVAVSPGIGFGEYGDEYVRIALIE 382
                        410       420
                 ....*....|....*....|.
gi 3122230   358 FEE--------VERFLKILEE 370
Cdd:PRK08636 383 NENrirqaarnIKKFLKELEG 403
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
27-371 6.43e-14

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 72.38  E-value: 6.43e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    27 EEIARA--YGIK--PE-DIIKLGSNENPWGPSPKIKEKILDEIDK----------IHQYPEPVnPILMKELSKFLNVDEE 91
Cdd:PRK06290  28 EKIKRAkrAAKEkhPDmELIDMGVGEPDEMADESVVEVLCEEAKKpenrgyadngIQEFKEAA-ARYMEKVFGVKDIDPV 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    92 NIIVGGDGADEIIDTIFRTFVDDGDEVIIPIP------TFTQYrVSATIHNAKIKyakydKEKDFKLNVESVLNNITDKT 165
Cdd:PRK06290 107 TEVIHSIGSKPALAMLPSCFINPGDVTLMTVPgypvtgTHTKY-YGGEVYNLPLL-----EENNFLPDLDSIPKDIKEKA 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   166 KVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PRK06290 181 KLLYLNYPNNPTGAVATKEFYEEVVDfakENNIIVVQDAAYAAltFDGKPLSFLSVPGAKEVGVEIHSLSKAYNMTGWRL 260
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   241 GYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDREFFERcVRDGIKSR-EMLYNGLKK--FKDIKvyP 308
Cdd:PRK06290 261 AFVVGNELIVKAFATVKdnndsgqfiAI-------QKAGIYALDHPEITEK-IREKYSRRlDKLVKILNEvgFKAEM--P 330
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230   309 SEANYLLVEL-KTMK-------AKEFCEELLKRGVIVrdCTSFDGLGdNYVRVSIgTFE--EVERFLKILEEI 371
Cdd:PRK06290 331 GGTFYLYVKApKGTKsgikfenAEEFSQYLIKEKLIS--TVPWDDAG-HFLRFSV-TFEakDEEEEDRILEEI 399
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
87-318 1.99e-13

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 71.31  E-value: 1.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    87 NVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTK 166
Cdd:PRK13355 205 NVDVDDIYTG-NGVSELINLSMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHYRCDEQSEWYPDIDDIRSKITSRTK 283
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   167 VIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYdwTQKAPEYDNVIVLrTF---SKVFGLAGM 238
Cdd:PRK13355 284 AIVIINPNNPTGALYPREVLQQIVDiarEHQLIIFSDEIYdrLVMDGLEH--TSIASLAPDLFCV-TFsglSKSHMIAGY 360
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   239 RVGYGV--ANKKII-DYMMRVKPIFSLTRLSQVCAITALRDREFFERCVRDGI-------KSREMLYNGLKKFKDIK-VY 307
Cdd:PRK13355 361 RIGWMIlsGNKRIAkDYIEGLNMLANMRLCSNVPAQSIVQTALGGHQSVKDYLvpggrvyEQRELVYNALNAIPGISaVK 440
                        250
                 ....*....|.
gi 3122230   308 PSEANYLLVEL 318
Cdd:PRK13355 441 PKAAFYIFPKI 451
PRK12414 PRK12414
putative aminotransferase; Provisional
112-340 2.10e-12

putative aminotransferase; Provisional


Pssm-ID: 183514  Cd Length: 384  Bit Score: 67.89  E-value: 2.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   112 VDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEkDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVER--- 188
Cdd:PRK12414 111 VHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPE-DFRVNWDEVAAAITPRTRMIIVNTPHNPSATVFSAADLARlaq 189
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   189 VINETDALVVIDHAY--IEYAKKEYDWTQKAPEY--DNVIVlRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--IFSL 262
Cdd:PRK12414 190 LTRNTDIVILSDEVYehVVFDGARHHSMARHRELaeRSVIV-SSFGKSYHVTGWRVGYCLAPAELMDEIRKVHQfmVFSA 268
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   263 TRLSQVCAITALRDRE-------FFERcvrdgikSREMLYNGLKKFKdIKVYPSEANYLLVELKTMKAKEFCEELLKRgv 335
Cdd:PRK12414 269 DTPMQHAFAEALAEPAsylglgaFYQR-------KRDLLARELAGSR-FELLPSEGSFFMLARFRHFSDESDSDFVLR-- 338

                 ....*
gi 3122230   336 IVRDC 340
Cdd:PRK12414 339 LIRDA 343
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
91-331 2.81e-12

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 67.50  E-value: 2.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    91 ENIIVGGDGADEIIdTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFL 170
Cdd:PTZ00433 105 DNVVLCSGVSHAIL-MALTALCDEGDNILVPAPGFPHYETVCKAYGIEMRFYNCRPEKDWEADLDEIRRLVDDRTKALIM 183
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   171 CTPNNPTGNIIENRDVERVINETDAL---VVIDHAYIEYAKKEYDWTQKAPEYDNV--IVLRTFSKVFGLAGMRVGYGVa 245
Cdd:PTZ00433 184 TNPSNPCGSNFSRKHVEDIIRLCEELrlpLISDEIYAGMVFNGATFTSVADFDTTVprVILGGTAKNLVVPGWRLGWLL- 262
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   246 nkkIIDyMMRVKPIF--SLTRLSQV----CAI------TALRD--REFFERCVRDGIKSREMLYNGLKKFKDIK-VYPSE 310
Cdd:PTZ00433 263 ---LVD-PHGNGGDFldGMKRLGMLvcgpCSVvqaalgEALLNtpQEHLEQIVAKLEEGAMVLYNHIGECIGLSpTMPRG 338
                        250       260
                 ....*....|....*....|....*..
gi 3122230   311 ANYLLVELKTMKAK------EFCEELL 331
Cdd:PTZ00433 339 SMFLMSRLDLEKFRdiksdvEFYEKLL 365
PRK09082 PRK09082
methionine aminotransferase; Validated
99-245 4.73e-11

methionine aminotransferase; Validated


Pssm-ID: 181642 [Multi-domain]  Cd Length: 386  Bit Score: 63.40  E-value: 4.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKeKDFKLNVESVLNNITDKTKVIFLCTPNNPTG 178
Cdd:PRK09082  99 GATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQP-PDFRVDWQRFAAAISPRTRLIILNTPHNPSG 177
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230   179 NIIENRDVER---VINETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK09082 178 TVWSAADMRAlwqLIAGTDIYVLSDEVYehIVFDGAGHASVLRHPElRERAFVVSSFGKTYHVTGWKVGYCVA 250
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
24-368 7.76e-11

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 62.77  E-value: 7.76e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    24 KSKEEIARAygikPEDIIKLGSNENPWGPSPKIKEKILDEI-DKIHQYPEPVN-PILMKELSKF------LNVDEENIIV 95
Cdd:PRK07337  20 KEAQALERA----GRDIIHMGIGEPDFTAPEPVVEAAARALrRGVTQYTSALGlAPLREAIAAWyarrfgLDVAPERIVV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    96 GGdGADEIIDTIFRTFVDDGDEVIIPIPTFTQYR--VSATihNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTP 173
Cdd:PRK07337  96 TA-GASAALLLACLALVERGDEVLMPDPSYPCNRhfVAAA--EGRPVLVPSGPAERFQLTAADVEAAWGERTRGVLLASP 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   174 NNPTGNIIENRDVERVINETDA---LVVIDHAYIEYAkkeYDwtqKAPEY-----DNVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK07337 173 SNPTGTSIAPDELRRIVEAVRArggFTIVDEIYQGLS---YD---AAPVSalslgDDVITINSFSKYFNMTGWRLGWLVV 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   246 NKKIIdymmrvkPIFSltRLSQ---VCAIT-----AL-------------RDREFFERcvRDGI-KSREMLynGLKkfkd 303
Cdd:PRK07337 247 PEALV-------GTFE--KLAQnlfICASAlaqhaALacfepdtlaiyerRRAEFKRR--RDFIvPALESL--GFK---- 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   304 IKVYPSEANYLLVELKTMKAK------EFCEELLKR-GVIV---RDCTSFDGLgdNYVRVSIGTF-----EEVERFLKIL 368
Cdd:PRK07337 310 VPVMPDGAFYVYADCRGVAHPaagdsaALTQAMLHDaGVVLvpgRDFGPHAPR--DYIRLSYATSmsrleEAVARLGKLF 387
PRK09265 PRK09265
aminotransferase AlaT; Validated
85-244 1.14e-10

aminotransferase AlaT; Validated


Pssm-ID: 181738  Cd Length: 404  Bit Score: 62.52  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    85 FLNVDEENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDK 164
Cdd:PRK09265  90 IPDVDVDDIYIG-NGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVHYLCDEEAGWFPDLDDIRSKITPR 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   165 TKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAY--IEYAKKEYdwTQKAPEYDNVIVLrTF---SKVFGLA 236
Cdd:PRK09265 169 TKAIVIINPNNPTGAVYSKELLEEIVEiarQHNLIIFADEIYdkILYDGAVH--ISIASLAPDLLCV-TFnglSKAYRVA 245

                 ....*...
gi 3122230   237 GMRVGYGV 244
Cdd:PRK09265 246 GFRVGWMV 253
avtA PRK09440
valine--pyruvate transaminase; Provisional
160-372 1.17e-10

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 62.56  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   160 NITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY------IEYAKKEYDWTqkapeyDNVIVLRTFS 230
Cdd:PRK09440 175 HIDEDTGAICVSRPTNPTGNVLTDEELEKLDalaRQHNIPLLIDNAYgppfpgIIFSEATPLWN------PNIILCMSLS 248
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   231 KVfGLAGMRVGYGVANKKIIDYMMRVKPIFSL--TRLSQVCAITALRDREFFERCVRDgIKS-----REMLYNGLKK-FK 302
Cdd:PRK09440 249 KL-GLPGVRCGIVIADEEIIEALSNMNGIISLapGRLGPAIAAEMIESGDLLRLSETV-IRPfyrqkVQLAIALLRRyLP 326
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   303 DIKVY---PSEANYLLVELK--TMKAKEFCEELLKRGV-IVRDCTSFDGLGDNY------VRVSI-GTFEEVERFLKILE 369
Cdd:PRK09440 327 DEPCLihkPEGAIFLWLWFKdlPITTEELYQRLKARGVlVVPGHYFFPGLDEDWphahqcIRMNYvQDDEEIEKGIAILA 406

                 ...
gi 3122230   370 EII 372
Cdd:PRK09440 407 EEV 409
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
99-335 2.23e-10

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 61.59  E-value: 2.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQY----------RVSATIHNAkikyakydkEKDFKLNVESVLNNITDKTKVI 168
Cdd:PRK07777  93 GATEAIAAAVLGLVEPGDEVLLIEPYYDSYaaviamagahRVPVPLVPD---------GRGFALDLDALRAAVTPRTRAL 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   169 FLCTPNNPTGNII---ENRDVERVINETDALVVIDHAYIEYAkkeYDWTQKAP------EYDNVIVLRTFSKVFGLAGMR 239
Cdd:PRK07777 164 IVNSPHNPTGTVLtaaELAAIAELAVEHDLLVITDEVYEHLV---FDGARHLPlatlpgMRERTVTISSAAKTFNVTGWK 240
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   240 VGYGVANKKIIDYMMRVKPIFSLTRLS--QVCAITALR-DREFFERcVRDGIKS-REMLYNGLKKfKDIKVYPSEANYLL 315
Cdd:PRK07777 241 IGWACGPAPLIAAVRAAKQYLTYVGGApfQPAVAHALDhEDAWVAA-LRDSLQAkRDRLAAGLAE-AGFEVHDSAGTYFL 318
                        250       260
                 ....*....|....*....|....*
gi 3122230   316 V----ELKTMKAKEFCEELLKR-GV 335
Cdd:PRK07777 319 CadprPLGYDDGTEFCRALPERvGV 343
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
109-357 2.59e-10

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 61.26  E-value: 2.59e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  109 RTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAK-YDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE 187
Cdd:COG1168 105 RAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENPlILEDGRYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELE 184
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  188 RVIN---ETDALVVID--HA--------YIEYAKkeydwtqKAPEY-DNVIVLRTFSKVFGLAGMRVGYGV-ANKKI--- 249
Cdd:COG1168 185 RLAElceRHDVLVISDeiHAdlvlpghkHTPFAS-------LSEEAaDRTITLTSPSKTFNLAGLKASYAIiPNPALrar 257
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  250 IDYMMRVKPIFSLTRLSQVCAITALRD-REFFERcVRDGIKS-REMLYNGLKK-FKDIKVYPSEANYLL-V---ELKtMK 322
Cdd:COG1168 258 FARALEGLGLPSPNVLGLVATEAAYREgEEWLDE-LLAYLRGnRDLLAEFLAEhLPGVKVTPPEATYLAwLdcrALG-LD 335
                       250       260       270
                ....*....|....*....|....*....|....*.
gi 3122230  323 AKEFCEELLKR-GVIVRDCTSFDGLGDNYVRVSIGT 357
Cdd:COG1168 336 DEELAEFLLEKaGVALSDGATFGEGGEGFVRLNFAC 371
PRK09148 PRK09148
LL-diaminopimelate aminotransferase;
14-363 5.53e-10

LL-diaminopimelate aminotransferase;


Pssm-ID: 181674 [Multi-domain]  Cd Length: 405  Bit Score: 60.46  E-value: 5.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    14 VKKLKPYVpgksKEEI------ARAYGikpEDIIKLGSNeNPWGPSPK-IKEKILDEIDK--IHQYPEPVN-PILMKELS 83
Cdd:PRK09148   7 IRRLPPYV----FEQVnrlkaaARAAG---ADIIDLGMG-NPDLPTPQhIVDKLCETAQDprTHRYSASKGiPGLRRAQA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    84 KF------LNVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PRK09148  79 AYyarrfgVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPAEPDEEFFPALERA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   158 LNNITDKTKVIFLCTPNNPTGNIIE---NRDVERVINETDALVVIDHAYIE--YAKKEYDWTQKAPEYDNVIV-LRTFSK 231
Cdd:PRK09148 159 VRHSIPKPIALIVNYPSNPTAYVADldfYKDVVAFAKKHDIIILSDLAYSEiyFDGNPPPSVLQVPGAKDVTVeFTSMSK 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   232 VFGLAGMRVGYGVANKKIIDYMMRVK---------PIfsltrlsQVCAITALRDREFFERCVRDGIKS-REMLYNGLKKF 301
Cdd:PRK09148 239 TFSMAGWRMGFAVGNERLIAALTRVKsyldygaftPI-------QVAATAALNGPQDCIAEMRELYKKrRDVLVESFGRA 311
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   302 K-DIkvyPSEANYLLV------ELKTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVRvsIGTFEEVER 363
Cdd:PRK09148 312 GwDI---PPPAASMFAwapipeAFRHLGSLEFSKLLVEKaDVAVAPGVGFGEHGDGYVR--IALVENEQR 376
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
78-237 1.71e-09

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 56.24  E-value: 1.71e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   78 LMKELSKFLNVDEENIIV--GGDGADEiidTIFRTFVDDGDEVIIPIPTF-TQYRVSATIHNAKIKYAKYDKEKDFKLNV 154
Cdd:cd01494   5 LEEKLARLLQPGNDKAVFvpSGTGANE---AALLALLGPGDEVIVDANGHgSRYWVAAELAGAKPVPVPVDDAGYGGLDV 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  155 ESVLNN-ITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHAYIEYAkkeydwtQKAPEYDNV-----IVLRT 228
Cdd:cd01494  82 AILEELkAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGA-------SPAPGVLIPeggadVVTFS 154

                ....*....
gi 3122230  229 FSKVFGLAG 237
Cdd:cd01494 155 LHKNLGGEG 163
PRK07550 PRK07550
aminotransferase;
115-256 2.92e-09

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 58.05  E-value: 2.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   115 GDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNII---ENRDVERVIN 191
Cdd:PRK07550 114 GDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGPGLLPDPAAAEALITPRTRAIALVTPNNPTGVVYppeLLHELYDLAR 193
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 3122230   192 ETDALVVIDHAYIEYAKK---------EYDWTqkapeyDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRV 256
Cdd:PRK07550 194 RHGIALILDETYRDFDSGggaphdlfaDPDWD------DTLVHLYSFSKSYALTGHRVGAVVASPARIAEIEKF 261
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
8-355 3.29e-09

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 57.87  E-value: 3.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230      8 NKVRDVVKKLKPYvPGKSKEEIARAYGiKPEDIIKLGsnenpwgPSPKIKEKILDEIDKiHQY----PEPVNPILMKELS 83
Cdd:TIGR01264  14 NPIRAIVDNMKVK-PNPEKPMIKLSIG-DPTVFGNLP-------TDPEVMQAMKDSLDS-GKYngyaPTVGALSAREAIA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     84 KFL----NVDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLN 159
Cdd:TIGR01264  84 SYYhnpdGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPGFPLYETLAESMGIEVKLYNLLPDKSWEIDLKQLES 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    160 NITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHAYIEYAKKEY---------DWTQKAPeydnVIVLRTFS 230
Cdd:TIGR01264 164 LIDEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFsgatfeplaSLSSTVP----ILSCGGLA 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    231 KVFGLAGMRVGYGVankkIIDYMMRVKPIFS-LTRLSQV----CAIT--ALRD------REFFERcVRDGIKSREML-YN 296
Cdd:TIGR01264 240 KRWLVPGWRLGWII----IHDRRGILRDIRDgLVKLSQRilgpCTIVqgALPSillrtpQEYFDG-TLSVLESNAMLcYG 314
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230    297 GLKKFKDIK-VYPSEANYLLVELKTMKAK------EFCEELL-KRGVIVRDCTSFDGLGdnYVRVSI 355
Cdd:TIGR01264 315 ALAAVPGLRpVMPSGAMYMMVGIEMEHFPefkndvEFTERLVaEQSVFCLPGSCFEYPG--FFRVVL 379
DAPAT_plant TIGR03542
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ...
88-249 3.48e-08

LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).


Pssm-ID: 163316  Cd Length: 402  Bit Score: 54.73  E-value: 3.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     88 VDEENIIVGgDGADEIIDTIFRTFVDDgDEVIIPIPTFTQYRVSATIHNA-----------KIKYAKYDKEKDFklnVES 156
Cdd:TIGR03542  93 IDPEEIFIS-DGAKCDVFRLQSLFGPD-NTVAVQDPVYPAYLDSNVMAGRagvldddgrysKITYLPCTAENNF---IPE 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    157 VLNNitDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAY---------------IEYAKKeydwtqkap 218
Cdd:TIGR03542 168 LPEE--PHIDIIYLCSPNNPTGTVLTKEQLKELVdyaNEHGSLILFDAAYsafisdpslphsifeIPGARF--------- 236
                         170       180       190
                  ....*....|....*....|....*....|.
gi 3122230    219 eydNVIVLRTFSKVFGLAGMRVGYGVANKKI 249
Cdd:TIGR03542 237 ---CAIEFRSFSKTAGFTGVRLGWTVVPKEL 264
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
75-242 3.08e-07

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 51.89  E-value: 3.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    75 NPILMKELSKFLN------VDEENIIVGgDGADEIIDTIFRTFV-DDGDEVIIPIPTFTQYrvSATIHNAKIKYAKY--D 145
Cdd:PTZ00377 117 YPFVRKAVAAFIErrdgvpKDPSDIFLT-DGASSGIKLLLQLLIgDPSDGVMIPIPQYPLY--SAAITLLGGKQVPYylD 193
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   146 KEKDFKLNVES--------VLNNITdkTKVIFLCTPNNPTGNIIENRDVERVIN---ETDALVVIDHAYIE--YA----- 207
Cdd:PTZ00377 194 EEKGWSLDQEEleeayeqaVRNGIT--PRALVVINPGNPTGQVLTRDVMEEIIKfcyEKGIVLMADEVYQEniYDgekpf 271
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 3122230   208 ----KKEYDWTqkaPEYDNVIVLRTF---SK-VFGLAGMRVGY 242
Cdd:PTZ00377 272 isfrKVLLELP---AEYNTDVELVSFhstSKgIIGECGRRGGY 311
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
76-245 1.12e-06

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 50.05  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    76 PILMKELSKF------LNVDEENIIV--GGDGAdeiIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKE 147
Cdd:PRK08960  72 PALREAIAGFyaqrygVDVDPERILVtpGGSGA---LLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPD 148
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   148 KDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIeNRD----VERVINETDALVVIDHAY--IEYakkEYDWTQKAPEYD 221
Cdd:PRK08960 149 SRYQLTPALVERHWNADTVGALVASPANPTGTLL-SRDelaaLSQALRARGGHLVVDEIYhgLTY---GVDAASVLEVDD 224
                        170       180
                 ....*....|....*....|....
gi 3122230   222 NVIVLRTFSKVFGLAGMRVGYGVA 245
Cdd:PRK08960 225 DAFVLNSFSKYFGMTGWRLGWLVA 248
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
98-369 1.32e-06

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 49.76  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    98 DGADEIIDT------IFRTF---VDDGDEVIIPIPTFTQYR-----VSATIHNAKIKYAKYDKEKDfkLNVESVLNNITD 163
Cdd:PRK06207 100 DAADELIITpgtqgaLFLAVaatVARGDKVAIVQPDYFANRklvefFEGEMVPVQLDYLSADKRAG--LDLDQLEEAFKA 177
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   164 KTKVIFLCTPNNPTGNII---ENRDVERVINETDALVVIDHAY--IEYAKKEYDWTQKAPE-YDNVIVLRTFSKVFGLAG 237
Cdd:PRK06207 178 GVRVFLFSNPNNPAGVVYsaeEIAQIAALARRYGATVIVDQLYsrLLYDGTSYTHLRALPIdPENVITIMGPSKTESLSG 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   238 MRVGYGVANKKIIDYMMRVKPIFSLtRLSQVCaiTALRDREFFER--CVRDGIKS----REMLYNGLKKFKDIKVYPSEA 311
Cdd:PRK06207 258 YRLGVAFGSPAIIDRMEKLQAIVSL-RAAGYS--QAVLRTWFSEPdgWMKDRIARhqaiRDDLLRVLRGVEGVFVRAPQA 334
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230   312 -NYLLVELKTMKAK--EFCEEL-LKRGVIVRDCTSFDGLGDNYVRVSI-----GTFEEVERFLKILE 369
Cdd:PRK06207 335 gSYLFPRLPRLAVSlhDFVKILrLQAGVIVTPGTEFSPHTADSIRLNFsqdhaAAVAAAERIAQLIE 401
PRK08637 PRK08637
hypothetical protein; Provisional
111-360 2.10e-06

hypothetical protein; Provisional


Pssm-ID: 181512  Cd Length: 388  Bit Score: 49.18  E-value: 2.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   111 FVDDGDEVIIPIPTFTQYR-VSATIHNAKI-KYAKYDKEKDFKLN--VESVLNNITDKTKVIFLCTPNNPTG---NIIEN 183
Cdd:PRK08637  89 FVDQGDTVLLPDHNWGNYKlTFNTRRGAEIvTYPIFDEDGGFDTDalKEALQAAYNKGKVIVILNFPNNPTGytpTEKEA 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   184 RDVERVINE-----TDALVVIDHAY--IEYAK--KEYDWTQKAPEYDNVIVLRT--FSKVFGLAGMRVG----------- 241
Cdd:PRK08637 169 TAIVEAIKEladagTKVVAVVDDAYfgLFYEDsyKESLFAALANLHSNILAVKLdgATKEEFVWGFRVGfitfgtkagss 248
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   242 ---YGVANKKIIDyMMRVKpIFSLTRLSQVCAITALRDREFFER--------CVRdGIKSREMLYNGlkKFKDI-KVYPS 309
Cdd:PRK08637 249 qtvKEALEKKVKG-LIRSN-ISNGPHPSQSAVLRALNSPEFDKEkqekfqilKER-YEKTKEVLYDG--KYDDAwQAYPF 323
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 3122230   310 EANYLL-VELKTMKAKEFCEELLKR---GVIvrdctsfdGLGDNYVRVSIGTFEE 360
Cdd:PRK08637 324 NSGYFMcLKLKGVDAEELRVHLLEKygiGTI--------ALNETDLRIAFSCVEE 370
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
147-352 3.15e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 48.52  E-value: 3.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   147 EKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVI---NETDALVVIDHAYIEYAkkeYDWTQKAP----- 218
Cdd:PRK07366 148 ENDFLPVFADIPTEVLAQARLMVLSYPHNPTTAIAPLSFFQEAVafcQQHDLVLVHDFPYVDLV---FDGEVEPPsilqa 224
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   219 --EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKPIFSLTRLSQVC--AITALR-DREFFERCVRDGIKSREM 293
Cdd:PRK07366 225 dpEKSVSIEFFTLSKSYNMGGFRIGFAIGNAQLIQALRQVKAVVDFNQYRGILngAIAALTgPQATVQQTVQIFRQRRDA 304
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230   294 LYNGLKKFKDIKVYPSEANYL---LVELKTMKAKEFCEELLKR-GVIVRDCTSFDGLGDNYVR 352
Cdd:PRK07366 305 FINALHQIGWPVPLPEATMYVwakLPEPWQGNSVEFCTQLVAQtGVAASPGSGFGKSGEGYVR 367
PLN02376 PLN02376
1-aminocyclopropane-1-carboxylate synthase
39-311 5.26e-06

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178004 [Multi-domain]  Cd Length: 496  Bit Score: 48.15  E-value: 5.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    39 DIIKLGSNENPwgpspkikEKILDEIDKIHQYPEPVNPILMKELSKF---------------LNVDEENIIVGGdGADEI 103
Cdd:PLN02376  61 DLIKDWVKENP--------EASICTLEGIHQFSDIANFQDYHGLKKFrqaiahfmgkarggkVTFDPERVVMSG-GATGA 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   104 IDTIFRTFVDDGDEVIIPIPTFTQY----RVSATIHNAKIKYAKYDkekDFKLNVESV------LNNITDKTKVIFLCTP 173
Cdd:PLN02376 132 NETIMFCLADPGDVFLIPSPYYAAFdrdlRWRTGVEIIPVPCSSSD---NFKLTVDAAdwaykkAQESNKKVKGLILTNP 208
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   174 NNPTGNIIEN---RDVERVINETDALVVIDHAY----------IEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRV 240
Cdd:PLN02376 209 SNPLGTMLDKdtlTNLVRFVTRKNIHLVVDEIYaatvfaggdfVSVAEVVNDVDISEVNVDLIHIVYSLSKDMGLPGFRV 288
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230   241 GYGVA-NKKIIDYMMRVKPIFSLTRLSQVCAITALRDREF-----FERCVRDGIKSReMLYNGLKKfKDIKVYPSEA 311
Cdd:PLN02376 289 GIVYSfNDSVVSCARKMSSFGLVSSQTQLMLASMLSDDQFvdnflMESSRRLGIRHK-VFTTGIKK-ADIACLTSNA 363
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
78-304 6.75e-06

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 47.84  E-value: 6.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    78 LMKELSKFLNVDEENIIVGGDGADEIIDTIFrtfVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PLN00145 107 LSRDLPYELSTDDIYLTAGCAQAIEIIMSVL---AQPGANILLPRPGYPLYEARAVFSGLEVRHFDLLPERGWEVDLEGV 183
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   158 lNNITDKTKV-IFLCTPNNPTGNIIeNRDVERVINETDA----LVVIDHAY--IEYAKKEYD----WTQKAPeydnVIVL 226
Cdd:PLN00145 184 -EALADENTVaMVIINPNNPCGSVY-SYEHLAKIAETARklgiLVIADEVYdhLTFGSKPFVpmgvFGEVAP----VLTL 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   227 RTFSKVFGLAGMRVGYGVA--------NKKIIDYMMRVKPI------FSLTRLSQVCAITalrDREFFERCVRDGIKSRE 292
Cdd:PLN00145 258 GSISKRWVVPGWRLGWIATcdpngilkETKVVDSIRNYLNIstdpatFVQGAIPQIIANT---KEEFFTKTLGLLKETAD 334
                        250
                 ....*....|..
gi 3122230   293 MLYNGLKKFKDI 304
Cdd:PLN00145 335 ICYEKIKEIKCI 346
Cys_Met_Meta_PP pfam01053
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ...
104-200 7.52e-06

Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.


Pssm-ID: 395837 [Multi-domain]  Cd Length: 376  Bit Score: 47.61  E-value: 7.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    104 IDTIFRTFVDDGDEVIIPI----PTFTQYRVSATIHNAKIKYAKYDKEKDFKlnvesvlNNITDKTKVIFLCTPNNPTGN 179
Cdd:pfam01053  75 ITAAILALLKAGDHIVATDdlygGTYRLFNKVLPRFGIEVTFVDTSDPEDLE-------AAIKPNTKAVYLETPTNPLLK 147
                          90       100
                  ....*....|....*....|.
gi 3122230    180 IIENRDVERVINETDALVVID 200
Cdd:pfam01053 148 VVDIEAIAKLAKKHGILVVVD 168
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
41-245 2.32e-05

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 46.02  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    41 IKLGSNEnPWGPSPK-IKEKILDEIDKIHQYPEPVN-PILMKELSKFLN-------VDEENIIVGGDGADEIIDTIFRTF 111
Cdd:PRK09147  32 ISLSIGE-PKHPTPAfIKDALAANLDGLASYPTTAGlPALREAIAAWLErryglpaLDPATQVLPVNGSREALFAFAQTV 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   112 VDDGDE---VIIPIPtFTQ-YRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVE 187
Cdd:PRK09147 111 IDRDGPgplVVCPNP-FYQiYEGAALLAGAEPYFLNCDPANNFAPDFDAVPAEVWARTQLLFVCSPGNPTGAVLPLDDWK 189
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 3122230   188 RVINETDAL-VVI--DHAYIE-YakkeYDwTQKAP-------------EYDNVIVLRTFSKVFGLAGMRVGYgVA 245
Cdd:PRK09147 190 KLFALSDRYgFVIasDECYSEiY----FD-EAAPPlglleaaaelgrdDFKRLVVFHSLSKRSNVPGLRSGF-VA 258
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
78-337 2.78e-05

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 45.77  E-value: 2.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    78 LMKELSKFLNVDEENIIVGGDGADEIIdtiFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESV 157
Cdd:PLN00143  87 LSNDLPYQLSPDDVYLTLGCKHAAEII---IKVLARPEANILLPRPGFPDVETYAIFHHLEIRHFDLLPEKGWEVDLDAV 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   158 LNNITDKTKVIFLCTPNNPTGNIIENRDVERvINET----DALVVIDHAY--IEYAKKEYDWTQKAPEYDNVIVLRTFSK 231
Cdd:PLN00143 164 EAIADENTIAMVIINPGNPCGSVYSYEHLNK-IAETarklGILVIADEVYghIVFGSKPFVPMGLFASIVPVITLGSISK 242
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   232 VFGLAGMRVGY-------------GVAN--KKIIDYmMRVKPIFSLTRLSQVCAITAlrdREFFERCVRDGIKSREMLYN 296
Cdd:PLN00143 243 RWMIPGWGLGWlvtcdpsgllqicEIADsiKKALNP-APFPPTFIQAAIPEILEKTT---EDFFSKTINILRAALAFCYD 318
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 3122230   297 GLKKFKDIKV--YPSEANYLLVELKTMKAK------EFCEELLKRGVIV 337
Cdd:PLN00143 319 KLKEIPCIMCpqKAEGAFFALVKLNLLLLEdieddmEFCLKLAKEESLI 367
PTZ00376 PTZ00376
aspartate aminotransferase; Provisional
58-241 4.50e-05

aspartate aminotransferase; Provisional


Pssm-ID: 240390  Cd Length: 404  Bit Score: 44.91  E-value: 4.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    58 EKILDEIDKIHQYPePVNPI-LMKELSKFL-------NVDEENII----VGGDGADEIIDTIFRTFVDDGDEVIIPIPTF 125
Cdd:PTZ00376  56 EKIIAEKNLDKEYL-PIEGLqSFIEAAQKLlfgeasyALAEKRIAtvqaLSGTGALRLGFEFLKRFLPAGTTVYVSNPTW 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   126 TQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLN---NITDKTKVIFLCTPNNPTG---NIIENRDVERVINETDALVVI 199
Cdd:PTZ00376 135 PNHVNIFKSAGLNVKEYRYYDPKTKGLDFDGMLEdlrTAPNGSVVLLHACAHNPTGvdpTEEQWKEIADVMKRKNLIPFF 214
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 3122230   200 DHAYIEYAKK--EYD------WTQKAPEydnVIVLRTFSKVFGLAGMRVG 241
Cdd:PTZ00376 215 DMAYQGFASGdlDKDayairlFAERGVE---FLVAQSFSKNMGLYGERIG 261
PRK07811 PRK07811
cystathionine gamma-synthase; Provisional
104-200 4.56e-05

cystathionine gamma-synthase; Provisional


Pssm-ID: 236104 [Multi-domain]  Cd Length: 388  Bit Score: 45.02  E-value: 4.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   104 IDTIFRTFVDDGDEVIIPIPTFT-QYRVSATIHNA-KIKYAKYDKEkdfklNVESVLNNITDKTKVIFLCTPNNPTGNII 181
Cdd:PRK07811  89 TDCLLRAVLRPGDHIVIPNDAYGgTFRLIDKVFTRwGVEYTPVDLS-----DLDAVRAAITPRTKLIWVETPTNPLLSIT 163
                         90
                 ....*....|....*....
gi 3122230   182 ENRDVERVINETDALVVID 200
Cdd:PRK07811 164 DIAALAELAHDAGAKVVVD 182
CsdA COG0520
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
84-372 5.50e-05

Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];


Pssm-ID: 440286 [Multi-domain]  Cd Length: 396  Bit Score: 44.74  E-value: 5.50e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   84 KFLNVDEENIIVGGDGADEIIDTIFRTF--VDDGDEVIIP--------IPtftqYRVSATIHNAKIKYAKYDKekDFKLN 153
Cdd:COG0520  70 RFIGAASPDEIIFTRGTTEAINLVAYGLgrLKPGDEILITemehhsniVP----WQELAERTGAEVRVIPLDE--DGELD 143
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  154 VESVLNNITDKTKVIFLC-TPNNpTGNIIenrDVERVI---NETDALVVIDHAyieyakkeydwtQKAPEYD-NVIVLR- 227
Cdd:COG0520 144 LEALEALLTPRTKLVAVThVSNV-TGTVN---PVKEIAalaHAHGALVLVDGA------------QSVPHLPvDVQALGc 207
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  228 ---TFS--KVFGLAGMRVGYGvaNKKIIDYMmrvKPIF---------SLTR----------------LSQVCAI-TALrd 276
Cdd:COG0520 208 dfyAFSghKLYGPTGIGVLYG--KRELLEAL---PPFLggggmiewvSFDGttyadlprrfeagtpnIAGAIGLgAAI-- 280
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  277 rEFFERCVRDGIKSREM-----LYNGLKKFKDIKVY-PSEANYLL----VELKTMKAKEFCEELLKRGVIVRD---CTS- 342
Cdd:COG0520 281 -DYLEAIGMEAIEAREReltayALEGLAAIPGVRILgPADPEDRSgivsFNVDGVHPHDVAALLDDEGIAVRAghhCAQp 359
                       330       340       350
                ....*....|....*....|....*....|....*
gi 3122230  343 -FDGLG-DNYVRVSIG---TFEEVERFLKILEEII 372
Cdd:COG0520 360 lMRRLGvPGTVRASFHlynTEEEIDRLVEALKKLA 394
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
80-202 7.16e-05

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 44.55  E-value: 7.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230     80 KELSKFLNV-DEENIIV--GGDGADEIIDTIFRTFVDDGDEVIIpiptfTQYRVSATI---------HNAKIKYAKYDKe 147
Cdd:pfam00266  50 EKVAEFINApSNDEIIFtsGTTEAINLVALSLGRSLKPGDEIVI-----TEMEHHANLvpwqelakrTGARVRVLPLDE- 123
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 3122230    148 kDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVINETDALVVIDHA 202
Cdd:pfam00266 124 -DGLLDLDELEKLITPKTKLVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAA 177
PLN02656 PLN02656
tyrosine transaminase
53-304 8.54e-05

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 44.14  E-value: 8.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    53 SPKIKEKILDEI--DKIHQYPEPVN-PILMKELSKFLNVD------EENIIVGgDGADEIIDTIFRTFVDDGDEVIIPIP 123
Cdd:PLN02656  50 THVAQEAVVDALqsNKFNGYAPTVGlPQARRAIAEYLSRDlpyklsLDDVFIT-SGCTQAIDVALSMLARPGANILLPRP 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   124 TFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIENRDVERVINETDAL---VVID 200
Cdd:PLN02656 129 GFPIYELCAAFRHLEVRYVDLLPEKGWEVDLDAVEALADQNTVALVIINPGNPCGNVYSYQHLKKIAETAEKLkilVIAD 208
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   201 HAY--IEYAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVA--------NKKIIDymmRVKPIFSLTR------ 264
Cdd:PLN02656 209 EVYghLAFGSNPFVPMGVFGSIVPVLTLGSLSKRWIVPGWRLGWFVTtdpsgsfrDPKIVE---RIKKYFDILGgpatfi 285
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 3122230   265 LSQVCAITALRDREFFERCVrdgiksremlyNGLKKFKDI 304
Cdd:PLN02656 286 QAAVPTILEQTDESFFKKTI-----------NILKQSSDI 314
CGS_like cd00614
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ...
104-200 8.91e-05

CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.


Pssm-ID: 99738 [Multi-domain]  Cd Length: 369  Bit Score: 44.12  E-value: 8.91e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  104 IDTIFRTFVDDGDEVIIPI----PTFTQYRVSATIHNAKIKYAkydkekDFkLNVESVLNNITDKTKVIFLCTPNNPTGN 179
Cdd:cd00614  68 ISTVLLALLKAGDHVVASDdlygGTYRLFERLLPKLGIEVTFV------DP-DDPEALEAAIKPETKLVYVESPTNPTLK 140
                        90       100
                ....*....|....*....|.
gi 3122230  180 IIENRDVERVINETDALVVID 200
Cdd:cd00614 141 VVDIEAIAELAHEHGALLVVD 161
KBL_like cd06454
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ...
194-371 1.17e-04

KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.


Pssm-ID: 99747 [Multi-domain]  Cd Length: 349  Bit Score: 43.70  E-value: 1.17e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  194 DALVVID--HAY---------IEYAKKEYDwtqkapeyDNVIVLRTFSKVFGLAGmrvGYGVANKKIIDYMMRVKP--IF 260
Cdd:cd06454 162 GAILFVDeaHSVgvygphgrgVEEFGGLTD--------DVDIIMGTLGKAFGAVG---GYIAGSKELIDYLRSYARgfIF 230
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  261 SLTRLSQVCA--ITALRdrefferCVRDGIKSREMLYNGLKKFK------DIKVYPSE--ANYLLVELKTMKAKEFCEEL 330
Cdd:cd06454 231 STSLPPAVAAaaLAALE-------VLQGGPERRERLQENVRYLRrglkelGFPVGGSPshIIPPLIGDDPAKAVAFSDAL 303
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 3122230  331 LKRGVIVRDC----TSfdgLGDNYVRVSIG---TFEEVERFLKILEEI 371
Cdd:cd06454 304 LERGIYVQAIryptVP---RGTARLRISLSaahTKEDIDRLLEALKEV 348
MetC COG0626
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ...
104-200 2.79e-04

Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis


Pssm-ID: 440391 [Multi-domain]  Cd Length: 389  Bit Score: 42.73  E-value: 2.79e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230  104 IDTIFRTFVDDGDEVIIP----IPT-------FTQYRVSATIHNAkikyakydkekdfkLNVESVLNNITDKTKVIFLCT 172
Cdd:COG0626  86 ISAVLLALLKAGDHVVASddlyGGTrrlldkvLARFGIEVTFVDP--------------TDLAAVEAAIRPNTKLVFLET 151
                        90       100       110
                ....*....|....*....|....*....|.
gi 3122230  173 PNNPTGNIIenrDVERVIN---ETDALVVID 200
Cdd:COG0626 152 PSNPTLEVV---DIAAIAAiahAAGALLVVD 179
PRK07503 PRK07503
methionine gamma-lyase; Provisional
97-203 3.52e-04

methionine gamma-lyase; Provisional


Pssm-ID: 181005 [Multi-domain]  Cd Length: 403  Bit Score: 42.48  E-value: 3.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    97 GDGAdeiIDTIFRTFVDDGDEVIIpipTFTQYRVS-ATIHNAKIKYAKYDKEKDFKlNVESVLNNITDKTKVIFLCTPNN 175
Cdd:PRK07503  89 GMGA---ITATLWTLLRPGDEVIV---DQTLYGCTfAFLHHGLGEFGVTVRHVDLT-DPAALKAAISDKTRMVYFETPAN 161
                         90       100
                 ....*....|....*....|....*...
gi 3122230   176 PTGNIIENRDVERVINETDALVVIDHAY 203
Cdd:PRK07503 162 PNMRLVDIAAVAEIAHGAGAKVVVDNTY 189
PLN02187 PLN02187
rooty/superroot1
99-246 4.41e-04

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 42.02  E-value: 4.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230    99 GADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKEKDFKLNVESVLNNITDKTKVIFLCTPNNPTG 178
Cdd:PLN02187 139 GCNQGIEIVFESLARPNANILLPRPGFPHYDARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADENTVAMVVINPNNPCG 218
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3122230   179 NIIENRDVERVINETDAL---VVIDHAYIE--YAKKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVAN 246
Cdd:PLN02187 219 NVYSHDHLKKVAETARKLgimVISDEVYDRtiFGDNPFVSMGKFASIVPVLTLAGISKGWVVPGWKIGWIALN 291
PRK05958 PRK05958
8-amino-7-oxononanoate synthase; Reviewed
221-273 4.76e-03

8-amino-7-oxononanoate synthase; Reviewed


Pssm-ID: 235655 [Multi-domain]  Cd Length: 385  Bit Score: 38.60  E-value: 4.76e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 3122230   221 DNVIVLRTFSKVFGLAGmrvGYGVANKKIIDYMM-RVKP-IFSlTRLS--QVCAITA 273
Cdd:PRK05958 229 PDVILVGTLGKALGSSG---AAVLGSETLIDYLInRARPfIFT-TALPpaQAAAARA 281
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
121-371 7.71e-03

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 38.13  E-value: 7.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   121 PIPTFTQYRVSATIHNAKIKYAKYDKEKDFKlnvesvlNNITDKT----KVIFLCTPNNPTGNIIenrDVERVIN----- 191
Cdd:PRK05839 115 PNPFYQIYEGAAIASRAKVLLMPLTKENDFT-------PSLNEKElqevDLVILNSPNNPTGRTL---SLEELIEwvkla 184
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   192 -ETDALVVIDHAYIE-YAKkeydwtQKAP------------EYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVK 257
Cdd:PRK05839 185 lKHDFILINDECYSEiYEN------TPPPslleasilvgneSFKNVLVINSISKRSSAPGLRSGFIAGDASILKKYKAYR 258
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3122230   258 ---------PIfsltrlsQVCAITALRDREFFErcvrdgiKSREMLYNGLKKFKDI-KVYPSEANYlLVELKTMKAKEFC 327
Cdd:PRK05839 259 tylgcasplPL-------QKAAAVAWLDDEHAE-------FFRNIYAKNLKLAREIlGITIPPATF-YVWLPVDNDEEFT 323
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 3122230   328 EELLKRGVIVRDCTSF---DGLGDNYVRvsIGTFEEVERFLKILEEI 371
Cdd:PRK05839 324 KKLYQNEGIKVLPGSFlgrNGIGKGYVR--IALVYDTPKLEKALEII 368
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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