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Conserved domains on  [gi|1710872626|gb|TVQ36520|]
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antitoxin [Spirochaetaceae bacterium]

Protein Classification

BrnA antitoxin family protein( domain architecture ID 10009189)

BrnA antitoxin family protein similar to type II toxin-antitoxin system antitoxin BrnA that neutralizes the toxin BrnT

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5304 COG5304
Predicted DNA binding protein, CopG/RHH family [Transcription];
3-89 7.20e-27

Predicted DNA binding protein, CopG/RHH family [Transcription];


:

Pssm-ID: 444103  Cd Length: 90  Bit Score: 94.62  E-value: 7.20e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1710872626   3 YLDEEERQLIESLDRGDWNSIDDleeakSEARRYAEATLRKDQRMNIRMTERDLRNLKIRAAEDGLQYQTLVTMILHKYV 82
Cdd:COG5304     9 KLDKEEEEFLDSHDSGEYVDVPD-----SKFKPAAFELKPKDKRINIRLSESDLEAIKARANEEGIPYQTLIKSLLHKYV 83


                  ....*..
gi 1710872626  83 TGQLVER 89
Cdd:COG5304    84 TGRLVEK 90
 
Name Accession Description Interval E-value
COG5304 COG5304
Predicted DNA binding protein, CopG/RHH family [Transcription];
3-89 7.20e-27

Predicted DNA binding protein, CopG/RHH family [Transcription];


Pssm-ID: 444103  Cd Length: 90  Bit Score: 94.62  E-value: 7.20e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1710872626   3 YLDEEERQLIESLDRGDWNSIDDleeakSEARRYAEATLRKDQRMNIRMTERDLRNLKIRAAEDGLQYQTLVTMILHKYV 82
Cdd:COG5304     9 KLDKEEEEFLDSHDSGEYVDVPD-----SKFKPAAFELKPKDKRINIRLSESDLEAIKARANEEGIPYQTLIKSLLHKYV 83


                  ....*..
gi 1710872626  83 TGQLVER 89
Cdd:COG5304    84 TGRLVEK 90
CopG_antitoxin pfam12441
CopG antitoxin of type II toxin-antitoxin system; CopG antitoxin is a member of a type II ...
 5-78 4.92e-03

CopG antitoxin of type II toxin-antitoxin system; CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.


Pssm-ID: 463583  Cd Length: 79  Bit Score: 33.09  E-value: 4.92e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1710872626   5 DEEERQLIESLDRGDWNSIDDLEEAksearRYAEATlRKDQRMNIRMTERDLRNLKIRAAEDGLQYQTLVTMIL 78
Cdd:pfam12441   9 EEEAEEFWETHDLTEYVDWSQFKPV-----RFPELK-PKHKTISLRLPEDLLEALKILANARGIPYQSLIKMWL 76
 
Name Accession Description Interval E-value
COG5304 COG5304
Predicted DNA binding protein, CopG/RHH family [Transcription];
3-89 7.20e-27

Predicted DNA binding protein, CopG/RHH family [Transcription];


Pssm-ID: 444103  Cd Length: 90  Bit Score: 94.62  E-value: 7.20e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1710872626   3 YLDEEERQLIESLDRGDWNSIDDleeakSEARRYAEATLRKDQRMNIRMTERDLRNLKIRAAEDGLQYQTLVTMILHKYV 82
Cdd:COG5304     9 KLDKEEEEFLDSHDSGEYVDVPD-----SKFKPAAFELKPKDKRINIRLSESDLEAIKARANEEGIPYQTLIKSLLHKYV 83


                  ....*..
gi 1710872626  83 TGQLVER 89
Cdd:COG5304    84 TGRLVEK 90
CopG_antitoxin pfam12441
CopG antitoxin of type II toxin-antitoxin system; CopG antitoxin is a member of a type II ...
 5-78 4.92e-03

CopG antitoxin of type II toxin-antitoxin system; CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.


Pssm-ID: 463583  Cd Length: 79  Bit Score: 33.09  E-value: 4.92e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1710872626   5 DEEERQLIESLDRGDWNSIDDLEEAksearRYAEATlRKDQRMNIRMTERDLRNLKIRAAEDGLQYQTLVTMIL 78
Cdd:pfam12441   9 EEEAEEFWETHDLTEYVDWSQFKPV-----RFPELK-PKHKTISLRLPEDLLEALKILANARGIPYQSLIKMWL 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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