|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01212 |
PRK01212 |
homoserine kinase; Provisional |
1-289 |
2.91e-127 |
|
homoserine kinase; Provisional
Pssm-ID: 234920 [Multi-domain] Cd Length: 301 Bit Score: 364.47 E-value: 2.91e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 1 MIPFSVRVPASTANVGPGFDSVGIALSLYLDVVVKEKAD-----KWQVIHSFEESIPTD-DKNLIVSTACKVCPSIS--- 71
Cdd:PRK01212 1 MMMVKVRVPATSANLGPGFDSLGLALSLYDEVLVGDVVSveaefSIEVIGEGADKLPLDpEKNLVYQAALKFLEKLGkpp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 72 PHIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRI 151
Cdd:PRK01212 81 GLRIELEKNIPLGRGLGSSAASIVAGLVAANELAGLPLSKEELLQLATEGEGHPDNVAPALLGGLVLALEENGVISVKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 152 ESKELGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMErDHFHEPYRLELVPLLPSI 231
Cdd:PRK01212 161 VFDDLKWVVAIPNIELSTAEARAVLPKQYSLKDAVFNSSRAALLVAALYTGDYELAGRAMK-DVLHEPYRAKLIPGFAEV 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446534755 232 RKCAKEFGAYGTALSGAGPSIFILTPYEKRQEVAEQLARVFT---DMKVCELEIDHKGIIV 289
Cdd:PRK01212 240 RQAALEAGALGAGISGAGPTVFALCDKEDAEKVADALQKAFLqgiEGFVHVLRLDTAGARV 300
|
|
| ThrB |
COG0083 |
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the ... |
4-292 |
1.88e-119 |
|
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 439853 [Multi-domain] Cd Length: 302 Bit Score: 344.77 E-value: 1.88e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 4 FSVRVPASTANVGPGFDSVGIALSLYLDVVVKE-KADKWQVIHS--FEESIPTDDKNLIVSTACKVC----PSISPHIIE 76
Cdd:COG0083 3 VKVRVPATSANLGPGFDSLGLALSLYDEVEVERsDEPGLEIEIEgeGADELPTDEDNLVYQAALALLeklgKEPPGLRIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 77 VTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRIE-SKE 155
Cdd:COG0083 83 IEKGIPLGRGLGSSAAAIVAGLVAANALLGLPLSKEELLELATEGEGHPDNVAPALLGGLVLSRSDGEPVRVVRLPvPPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 156 LGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMErDHFHEPYRLELVPLLPSIRKCA 235
Cdd:COG0083 163 LKAVVVIPDFELSTKEARAVLPKQVPLKDAVFNSSRAALLVAALATGDYELLGRAME-DRLHEPYRAKLIPGFDEVKEAA 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446534755 236 KEFGAYGTALSGAGPSIFILTPYEKRQEVAEQLARVFTDM----KVCELEIDHKGIIVNKE 292
Cdd:COG0083 242 LEAGALGAGISGAGPTVLALADDEEAEAVAEAMKAAFAEAgidaRVYVLKIDNEGARVLES 302
|
|
| thrB |
TIGR00191 |
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine ... |
4-289 |
1.76e-81 |
|
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine kinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.P.aeruginosa homoserine kinase seems not to be homologous (see PROSITE:PDOC0054) [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 129295 [Multi-domain] Cd Length: 302 Bit Score: 248.09 E-value: 1.76e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 4 FSVRVPASTANVGPGFDSVGIALSLYLDVVVKE---KADKWQVIHS---FEESIPTD-DKNLIVSTACKVCP----SISP 72
Cdd:TIGR00191 1 FRVKVPASSANLGPGFDVLGAALSLYLGLTVTDvvaQESDDTEIEAegeGVEKIPTEpTDNLIYQVAKRFLDqlgiRMPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 73 HIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRIE 152
Cdd:TIGR00191 81 VKVTLEKNIPLGRGLGSSAAAIVAALAAANELCGLPLSKERLLDYASELEGHPDNVAPALLGGFQLAFVEDDKLEVLKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 153 SK-ELGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMeRDHFHEPYRLELVPLLPSI 231
Cdd:TIGR00191 161 IFsKLDWVLAIPNIEVSTAEARAVLPKAYPRQDLVFNLSHLAGLVHAIYQKKPDLGAIMM-KDRIHQPYRESLIPNLFKI 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446534755 232 RKCAKEFGAYGTALSGAGPSIFILTP----YEKRQEVAEQLARVFTDMKVCELEIDHKGIIV 289
Cdd:TIGR00191 240 KQAALEKGAYGITISGSGPTILAMADeefaEQKEQDLLEVLHKQGIEGTVHVLDFDNDGARV 301
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
75-135 |
1.83e-12 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 61.41 E-value: 1.83e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446534755 75 IEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNL-----TADQKVQIAtnfEGHPDNVAASILGG 135
Cdd:pfam00288 2 IEIESNIPLGAGLGSSAALAVALLLALNELFGLPLaklalEAEELAGGG---RGGGMDVAASLYGG 64
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01212 |
PRK01212 |
homoserine kinase; Provisional |
1-289 |
2.91e-127 |
|
homoserine kinase; Provisional
Pssm-ID: 234920 [Multi-domain] Cd Length: 301 Bit Score: 364.47 E-value: 2.91e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 1 MIPFSVRVPASTANVGPGFDSVGIALSLYLDVVVKEKAD-----KWQVIHSFEESIPTD-DKNLIVSTACKVCPSIS--- 71
Cdd:PRK01212 1 MMMVKVRVPATSANLGPGFDSLGLALSLYDEVLVGDVVSveaefSIEVIGEGADKLPLDpEKNLVYQAALKFLEKLGkpp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 72 PHIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRI 151
Cdd:PRK01212 81 GLRIELEKNIPLGRGLGSSAASIVAGLVAANELAGLPLSKEELLQLATEGEGHPDNVAPALLGGLVLALEENGVISVKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 152 ESKELGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMErDHFHEPYRLELVPLLPSI 231
Cdd:PRK01212 161 VFDDLKWVVAIPNIELSTAEARAVLPKQYSLKDAVFNSSRAALLVAALYTGDYELAGRAMK-DVLHEPYRAKLIPGFAEV 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446534755 232 RKCAKEFGAYGTALSGAGPSIFILTPYEKRQEVAEQLARVFT---DMKVCELEIDHKGIIV 289
Cdd:PRK01212 240 RQAALEAGALGAGISGAGPTVFALCDKEDAEKVADALQKAFLqgiEGFVHVLRLDTAGARV 300
|
|
| ThrB |
COG0083 |
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the ... |
4-292 |
1.88e-119 |
|
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 439853 [Multi-domain] Cd Length: 302 Bit Score: 344.77 E-value: 1.88e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 4 FSVRVPASTANVGPGFDSVGIALSLYLDVVVKE-KADKWQVIHS--FEESIPTDDKNLIVSTACKVC----PSISPHIIE 76
Cdd:COG0083 3 VKVRVPATSANLGPGFDSLGLALSLYDEVEVERsDEPGLEIEIEgeGADELPTDEDNLVYQAALALLeklgKEPPGLRIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 77 VTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRIE-SKE 155
Cdd:COG0083 83 IEKGIPLGRGLGSSAAAIVAGLVAANALLGLPLSKEELLELATEGEGHPDNVAPALLGGLVLSRSDGEPVRVVRLPvPPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 156 LGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMErDHFHEPYRLELVPLLPSIRKCA 235
Cdd:COG0083 163 LKAVVVIPDFELSTKEARAVLPKQVPLKDAVFNSSRAALLVAALATGDYELLGRAME-DRLHEPYRAKLIPGFDEVKEAA 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446534755 236 KEFGAYGTALSGAGPSIFILTPYEKRQEVAEQLARVFTDM----KVCELEIDHKGIIVNKE 292
Cdd:COG0083 242 LEAGALGAGISGAGPTVLALADDEEAEAVAEAMKAAFAEAgidaRVYVLKIDNEGARVLES 302
|
|
| thrB |
TIGR00191 |
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine ... |
4-289 |
1.76e-81 |
|
homoserine kinase; Homoserine kinase is part of the threonine biosynthetic pathway.Homoserine kinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.P.aeruginosa homoserine kinase seems not to be homologous (see PROSITE:PDOC0054) [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 129295 [Multi-domain] Cd Length: 302 Bit Score: 248.09 E-value: 1.76e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 4 FSVRVPASTANVGPGFDSVGIALSLYLDVVVKE---KADKWQVIHS---FEESIPTD-DKNLIVSTACKVCP----SISP 72
Cdd:TIGR00191 1 FRVKVPASSANLGPGFDVLGAALSLYLGLTVTDvvaQESDDTEIEAegeGVEKIPTEpTDNLIYQVAKRFLDqlgiRMPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 73 HIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEGHPDNVAASILGGTVIGALDGKDVSVVRIE 152
Cdd:TIGR00191 81 VKVTLEKNIPLGRGLGSSAAAIVAALAAANELCGLPLSKERLLDYASELEGHPDNVAPALLGGFQLAFVEDDKLEVLKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 153 SK-ELGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMeRDHFHEPYRLELVPLLPSI 231
Cdd:TIGR00191 161 IFsKLDWVLAIPNIEVSTAEARAVLPKAYPRQDLVFNLSHLAGLVHAIYQKKPDLGAIMM-KDRIHQPYRESLIPNLFKI 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446534755 232 RKCAKEFGAYGTALSGAGPSIFILTP----YEKRQEVAEQLARVFTDMKVCELEIDHKGIIV 289
Cdd:TIGR00191 240 KQAALEKGAYGITISGSGPTILAMADeefaEQKEQDLLEVLHKQGIEGTVHVLDFDNDGARV 301
|
|
| PTZ00299 |
PTZ00299 |
homoserine kinase; Provisional |
5-257 |
7.19e-33 |
|
homoserine kinase; Provisional
Pssm-ID: 140320 Cd Length: 336 Bit Score: 123.46 E-value: 7.19e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 5 SVRVPASTANVGPGFDSVGIALSLYLDVVVkEKADKWQVIHSFE--ESIPTDDKNLIVSTACKVCP-----SISPHIIEV 77
Cdd:PTZ00299 9 VLRVPATTANIGPAYDTLGMALSIFMELTV-EHADAFSMTVEGEgsEHISTDEDNMVVQACRLAFEeyahkSMPPLKFIM 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 78 TSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQK---VQIATNFEGHPDNVAASILGGTVIG-ALDGKDVSVVRIES 153
Cdd:PTZ00299 88 HSNIPYGCGCGSSSAAAVAGFVAGMKLCGLTMETENEealLQAIAKFEGHPDNAAPAIYGGIQLVyKKDNGRFLTYRVPT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 154 K-ELGVISLIPNE--ELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMmeRDHFHEPYRLElvPLLPS 230
Cdd:PTZ00299 168 PpNLSVVLFVPHNkmKANTHVTRNLIPTSVSLEDAVFNISRTSILVLALSTGDLRMLKSC--SDKLHEQQRSD--ALFPH 243
|
250 260 270
....*....|....*....|....*....|
gi 446534755 231 IRKC---AKEFGAYGTALSGAGPSIFILTP 257
Cdd:PTZ00299 244 FRPCvkaAREAGAHYAFLSGAGPSVCALVG 273
|
|
| PLN02451 |
PLN02451 |
homoserine kinase |
9-272 |
1.30e-27 |
|
homoserine kinase
Pssm-ID: 215248 Cd Length: 370 Bit Score: 109.88 E-value: 1.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 9 PASTANVGPGFDSVGIALSLYLDVVVKEkadkwqVIHSFE------ESIPTDDKNL----------IVSTACKVCPSISP 72
Cdd:PLN02451 59 PATVANLGPGFDFLGCAVDGLGDFVTAR------VDPGVRpgevsiSEITGDTGRLskdplrncagIAAIATMKLLGIRS 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 73 HIIEVTSN--IPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEG-----HPDNVAASILGGTV-IGALDGK 144
Cdd:PLN02451 133 VGLSLSLHkgLPLGSGLGSSAASAAAAAVAVNELFGSPLGKDDLVLAGLESEAkvsgyHADNIAPALMGGFVlIRSYEPL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 145 DVSVVRIES-KELGVISLIPNEELNTDESRSVLPKMFPFHEAVKASAISNVLVAALCQKRWEVVGEMMERDHFHEPYRLE 223
Cdd:PLN02451 213 HLIPLRFPSaKDLFFVLVSPDFEAPTKKMRAALPKEIPMKHHVWNCSQAAALVAAILQGDAVLLGEALSSDKIVEPTRAP 292
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 446534755 224 LVPLLPSIRKCAKEFGAYGTALSGAGPS-IFILTPYEKRQEVAEQLARVF 272
Cdd:PLN02451 293 LIPGMEAVKKAALEAGAYGCTISGAGPTaVAVIDDEEKGEEVGERMVEAF 342
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
75-135 |
1.83e-12 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 61.41 E-value: 1.83e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446534755 75 IEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNL-----TADQKVQIAtnfEGHPDNVAASILGG 135
Cdd:pfam00288 2 IEIESNIPLGAGLGSSAALAVALLLALNELFGLPLaklalEAEELAGGG---RGGGMDVAASLYGG 64
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
21-249 |
2.37e-09 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 57.16 E-value: 2.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 21 SVGIALSLYLDVVVKEKADKWQVIHSFE-----ESIPTDDKNL-----IVSTACKVCPSISPHI-IEVTSNIPLTRGLGS 89
Cdd:COG1577 19 AIAVAVDRRATVTVEPSDDDKLRIESPDlggtlDLDPLADAALryikaAIEAALEYLGLPLKGFdIEIDSEIPRKRGLGS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 90 SASAIVAGIELANQLGNLNLTADQKVQIA--TNFEGHP-----DNvAASILGGTVigALDGKDvSVVRIESKELGVISLI 162
Cdd:COG1577 99 SAAVAVAVIRALAAFYGVELSKEELFKLAleAEKIVHGnpsglDT-AASTYGGPI--YYQRGD-RAEPLELPKNLPLVVG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 163 pneelNTDESRS-------VLPKM----FPFHEAVKASA-ISNVLVAALCQKRWEVVGEMMERDHFHepyRLEL---VPL 227
Cdd:COG1577 175 -----DTGVPAStkelvakVRKLKernpELYEAFLEEIGdLVEEAIEALEEGDLEALGELMNENHGL---LRALgvsTPE 246
|
250 260
....*....|....*....|..
gi 446534755 228 LPSIRKCAKEFGAYGTALSGAG 249
Cdd:COG1577 247 LDRLVEAARKAGALGAKLTGAG 268
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
18-249 |
4.14e-08 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 53.06 E-value: 4.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 18 GFDSVGIALSLYLDVVVKEKADK--------WQVIHSFEESIPTDDKNLIVSTACKVCPSISPHIIEVTSNIPLTRGLGS 89
Cdd:TIGR00549 16 GEPAIAAPIPLRTTVTVIESSDGsfiesdlgRGSLDDAPDELDGLKYVLAEFLSRFSELNPPPLEITIESEIPPGRGLGS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 90 SASAIVAGIELANQLGNLNLTADQKVQIATNFE----GHP---DNvAASILGGTVigaLDGKDVSVVRIESKELGVISLI 162
Cdd:TIGR00549 96 SAAVAVALIRALADYFGSELSKEELAELANEAEkiahGKPsgiDT-ATSTSGGPV---YFEKGEGEFTKLISLDGYFVIA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 163 pneelNTDESRS---------VLPKMFPfhEAVKAS-----AISNVLVAALCQKRWEVVGEMMERDHfhepyrlEL---- 224
Cdd:TIGR00549 172 -----DTGVSGStkeavarvrQLLERFP--ELIDSImdaigELTLEAKAALQDGDVESLGELMNINQ-------GLlkal 237
|
250 260
....*....|....*....|....*...
gi 446534755 225 ---VPLLPSIRKCAKEFGAYGTALSGAG 249
Cdd:TIGR00549 238 gvsHPKLDQLVEIARKAGALGAKLTGAG 265
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
195-272 |
2.60e-07 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 47.46 E-value: 2.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 195 LVAALCQKRWEVVGEMMERDHF-HEP--YRLELVPLLPSIRKCAKEFGaYGTALSGA--GPSIFILTPYEKR-QEVAEQL 268
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAEsLEPllVVGILPPELDELLEALLELG-LGAKLSGSggGPTVFALFKDEDDaEEVARAL 79
|
....
gi 446534755 269 ARVF 272
Cdd:pfam08544 80 REAG 83
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
53-266 |
3.63e-06 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 47.74 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 53 TDDKNLIVSTACKVCPSISPH---IIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQ------KVQIATNFEG 123
Cdd:PRK03926 53 TGEKHPYVSAAIEKMREEADKdgvTVSITSQIPVGSGLGSSAAVTVATIGALNRLLGLGLSLEEiaklghKVELLVQGAA 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 124 HPDNVAASILGGTVIgALDGKdvsvvRIESKELGVI-----SLIPNEEL--NTDESRSVLPKMF-PFHEAV-KASAISNV 194
Cdd:PRK03926 133 SPTDTYVSTMGGFVT-IPDRK-----KLPFPECGIVvgytgSSGSTKELvaNVRKLKEEYPELIePILSSIgKISEKGEE 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 195 LVaalCQKRWEVVGEMMERDHfhepyRL---------ELVPLLPSIRKCakefGAYGTALSGAGPS--IFILTPYEKRQE 263
Cdd:PRK03926 207 LI---LSGDYVSLGELMNINQ-----GLldalgvstkELSELIYAARTA----GALGAKITGAGGGgcMVALAAPEKQSE 274
|
...
gi 446534755 264 VAE 266
Cdd:PRK03926 275 VAT 277
|
|
| PRK14613 |
PRK14613 |
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; |
157-275 |
5.15e-04 |
|
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase;
Pssm-ID: 173077 [Multi-domain] Cd Length: 297 Bit Score: 41.04 E-value: 5.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 157 GVISLIPnEELNTDESRSVLPKmfPFHEAVKA---SAISNVLVAALCQKRWEVVGEMMERDHfhEPYRLELVPLLPSIRK 233
Cdd:PRK14613 173 GILALTP-QVMNTGEMYALLKK--PLQESASQkngNTLSEDLISSLKVGDWVSLQGRLENDF--EPVAFQLHPELGVLKD 247
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 446534755 234 CAKEFGAYGTALSGAGPSIFILTP-YEKRQEVAEQLARVFTDM 275
Cdd:PRK14613 248 KFLEFGSSYCSLTGSGSSMYGLVQgLEIQEELLPRLRQEFSNL 290
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
70-118 |
6.52e-04 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 40.75 E-value: 6.52e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446534755 70 ISPHIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIA 118
Cdd:PRK03817 84 VGGVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLA 132
|
|
| PduX |
COG4542 |
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites ... |
75-247 |
1.30e-03 |
|
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443608 [Multi-domain] Cd Length: 286 Bit Score: 39.84 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 75 IEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIATNFEG-----HPDNVAASILGGTVIGALDgkdvsvv 149
Cdd:COG4542 73 IELRSDIPVGKGMASSTADIAATARAVARALGKELSPEELARLAVAIEPtdstmFPGLVLFDHREGRVLEPLG------- 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534755 150 riESKELGVISLIPNEELNTDE-SRSVLPKMFPFHEAVKASAIsNVLVAALCQKRWEVVGEMMERDHF----HEPYrlel 224
Cdd:COG4542 146 --PLPPLDILGLDSGGTVDTLAfNRRDLAELNRAEEPEIERAL-ALLREALRTGDLALLGEAATLSARanqrILPK---- 218
|
170 180
....*....|....*....|....*
gi 446534755 225 vPLLPSIRKCAKEFGAYG--TALSG 247
Cdd:COG4542 219 -PELEELLALAEELGALGvnVAHSG 242
|
|
| PRK04181 |
PRK04181 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional |
69-118 |
8.39e-03 |
|
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional
Pssm-ID: 235243 Cd Length: 257 Bit Score: 37.25 E-value: 8.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 446534755 69 SISPHIIEVTSNIPLTRGLGSSASAIVAGIELANQLGNLNLTADQKVQIA 118
Cdd:PRK04181 83 FFKKKAIEVEKNIPTGAGLGGGSSDAATFLLMLNEILNLKLSLEELAEIG 132
|
|
| |
