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Conserved domains on  [gi|492017277|ref|WP_005718887|]
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MULTISPECIES: 30S ribosomal protein S15 [Lactobacillus]

Protein Classification

30S ribosomal protein S15( domain architecture ID 10012506)

30S ribosomal protein S15 binds the central domain of 16S rRNA and is required for the assembly of the ribosomal small subunit.

Gene Ontology:  GO:0019843|GO:0003735|GO:0006412
PubMed:  24524803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
rpsO PRK05626
30S ribosomal protein S15; Reviewed
 1-89 4.75e-51

30S ribosomal protein S15; Reviewed


:

Pssm-ID: 180170  Cd Length: 89  Bit Score: 154.89  E-value: 4.75e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  1 MAISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRE 80
Cdd:PRK05626  1 MSLTKEKKAEIIKEYGRHEGDTGSPEVQVALLTERINHLTEHLKEHKKDHHSRRGLLKMVGQRRKLLDYLKKKDVERYRA 80


                ....*....
gi 492017277 81 LIKKLGLRR 89
Cdd:PRK05626 81 LIERLGLRR 89
 
Name Accession Description Interval E-value
rpsO PRK05626
30S ribosomal protein S15; Reviewed
 1-89 4.75e-51

30S ribosomal protein S15; Reviewed


Pssm-ID: 180170  Cd Length: 89  Bit Score: 154.89  E-value: 4.75e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  1 MAISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRE 80
Cdd:PRK05626  1 MSLTKEKKAEIIKEYGRHEGDTGSPEVQVALLTERINHLTEHLKEHKKDHHSRRGLLKMVGQRRKLLDYLKKKDVERYRA 80


                ....*....
gi 492017277 81 LIKKLGLRR 89
Cdd:PRK05626 81 LIERLGLRR 89
RpsO COG0184
Ribosomal protein S15P/S13E [Translation, ribosomal structure and biogenesis]; Ribosomal ...
 1-89 4.21e-45

Ribosomal protein S15P/S13E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S15P/S13E is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439954  Cd Length: 89  Bit Score: 139.81  E-value: 4.21e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  1 MAISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRE 80
Cdd:COG0184   1 MPLTKEEKEEIIKEYGRHEGDTGSPEVQIALLTERINNLTEHLKEHKKDHHSRRGLLKMVGKRRRLLDYLKKKDIERYRA 80


                ....*....
gi 492017277 81 LIKKLGLRR 89
Cdd:COG0184  81 LIAKLGLRK 89
S15_bact TIGR00952
ribosomal protein S15, bacterial/organelle; This model is built to recognize specifically ...
 4-89 4.86e-38

ribosomal protein S15, bacterial/organelle; This model is built to recognize specifically bacterial, chloroplast, and mitochondrial ribosomal protein S15. The homologous proteins of Archaea and Eukarya are designated S13. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 130027 [Multi-domain]  Cd Length: 86  Bit Score: 122.05  E-value: 4.86e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277   4 SKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIK 83
Cdd:TIGR00952  1 TKERKQEIIKEFQLHEKDTGSPEVQIALLTERINQLTEHLKANKKDHHSRRGLLKLVGRRRRLLKYLKRTDVERYRSLIK 80


                 ....*.
gi 492017277  84 KLGLRR 89
Cdd:TIGR00952 81 RLGLRR 86
Ribosomal_S15 pfam00312
Ribosomal protein S15;
8-88 5.71e-37

Ribosomal protein S15;


Pssm-ID: 459756  Cd Length: 81  Bit Score: 119.07  E-value: 5.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277   8 KEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLGL 87
Cdd:pfam00312  1 KQEIIKEFGRHPGDTGSPEVQIALLTERINNLTEHLKEHKKDKHSRRGLLKLVGKRRRLLKYLKRKDVERYRYLIEKLGL 80


                 .
gi 492017277  88 R 88
Cdd:pfam00312 81 R 81
Ribosomal_S15p_S13e cd00353
Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and ...
 7-86 6.22e-28

Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome. S15 also plays an important autoregulatory role by binding and preventing its own mRNA from being translated. S15 has a predominantly alpha-helical fold that is highly structured except for the N-terminal alpha helix.


Pssm-ID: 238213  Cd Length: 80  Bit Score: 96.03  E-value: 6.22e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  7 EKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLG 86
Cdd:cd00353   1 KKQEILKEFGLAEGDTGSPEVQLALLTERIVNLTEHLEKNKKDKHSKRGLLLLVSKRRRLLKYLKRKDRLRYEWLIEKLG 80
 
Name Accession Description Interval E-value
rpsO PRK05626
30S ribosomal protein S15; Reviewed
 1-89 4.75e-51

30S ribosomal protein S15; Reviewed


Pssm-ID: 180170  Cd Length: 89  Bit Score: 154.89  E-value: 4.75e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  1 MAISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRE 80
Cdd:PRK05626  1 MSLTKEKKAEIIKEYGRHEGDTGSPEVQVALLTERINHLTEHLKEHKKDHHSRRGLLKMVGQRRKLLDYLKKKDVERYRA 80


                ....*....
gi 492017277 81 LIKKLGLRR 89
Cdd:PRK05626 81 LIERLGLRR 89
RpsO COG0184
Ribosomal protein S15P/S13E [Translation, ribosomal structure and biogenesis]; Ribosomal ...
 1-89 4.21e-45

Ribosomal protein S15P/S13E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S15P/S13E is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439954  Cd Length: 89  Bit Score: 139.81  E-value: 4.21e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  1 MAISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRE 80
Cdd:COG0184   1 MPLTKEEKEEIIKEYGRHEGDTGSPEVQIALLTERINNLTEHLKEHKKDHHSRRGLLKMVGKRRRLLDYLKKKDIERYRA 80


                ....*....
gi 492017277 81 LIKKLGLRR 89
Cdd:COG0184  81 LIAKLGLRK 89
S15_bact TIGR00952
ribosomal protein S15, bacterial/organelle; This model is built to recognize specifically ...
 4-89 4.86e-38

ribosomal protein S15, bacterial/organelle; This model is built to recognize specifically bacterial, chloroplast, and mitochondrial ribosomal protein S15. The homologous proteins of Archaea and Eukarya are designated S13. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 130027 [Multi-domain]  Cd Length: 86  Bit Score: 122.05  E-value: 4.86e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277   4 SKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIK 83
Cdd:TIGR00952  1 TKERKQEIIKEFQLHEKDTGSPEVQIALLTERINQLTEHLKANKKDHHSRRGLLKLVGRRRRLLKYLKRTDVERYRSLIK 80


                 ....*.
gi 492017277  84 KLGLRR 89
Cdd:TIGR00952 81 RLGLRR 86
Ribosomal_S15 pfam00312
Ribosomal protein S15;
8-88 5.71e-37

Ribosomal protein S15;


Pssm-ID: 459756  Cd Length: 81  Bit Score: 119.07  E-value: 5.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277   8 KEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLGL 87
Cdd:pfam00312  1 KQEIIKEFGRHPGDTGSPEVQIALLTERINNLTEHLKEHKKDKHSRRGLLKLVGKRRRLLKYLKRKDVERYRYLIEKLGL 80


                 .
gi 492017277  88 R 88
Cdd:pfam00312 81 R 81
Ribosomal_S15p_S13e cd00353
Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and ...
 7-86 6.22e-28

Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome. S15 also plays an important autoregulatory role by binding and preventing its own mRNA from being translated. S15 has a predominantly alpha-helical fold that is highly structured except for the N-terminal alpha helix.


Pssm-ID: 238213  Cd Length: 80  Bit Score: 96.03  E-value: 6.22e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492017277  7 EKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLG 86
Cdd:cd00353   1 KKQEILKEFGLAEGDTGSPEVQLALLTERIVNLTEHLEKNKKDKHSKRGLLLLVSKRRRLLKYLKRKDRLRYEWLIEKLG 80
rps15 CHL00027
ribosomal protein S15
 18-89 1.57e-16

ribosomal protein S15


Pssm-ID: 214339  Cd Length: 90  Bit Score: 67.68  E-value: 1.57e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492017277 18 HEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYRELIKKLGLRR 89
Cdd:CHL00027 15 KEENRGSVEFQVFSFTNKIRRLTSHLELHKKDYSSQRGLRKILGKRQRLLAYLSKKNRVRYKKLISQLGIRE 86
S15_NS1_EPRS_RNA-bind cd00677
S15/NS1/EPRS_RNA-binding domain. This short domain consists of a helix-turn-helix structure, ...
 26-71 2.25e-10

S15/NS1/EPRS_RNA-binding domain. This short domain consists of a helix-turn-helix structure, which can bind to several types of RNA. It is found in the ribosomal protein S15, the influenza A viral nonstructural protein (NSA) and in several eukaryotic aminoacyl tRNA synthetases (aaRSs), where it occurs as a single or a repeated unit. It is involved in both protein-RNA interactions by binding tRNA and protein-protein interactions in the formation of tRNA-synthetases into multienzyme complexes. While this domain lacks significant sequence similarity between the subgroups in which it is found, they share similar electrostatic surface potentials and thus are likely to bind to RNA via the same mechanism.


Pssm-ID: 238361  Cd Length: 46  Bit Score: 50.59  E-value: 2.25e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 492017277 26 EVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLE 71
Cdd:cd00677   1 EVQIALLTERIRNLKEHLAKNKKDKHSKRGLDLLVSKRLRLLKYLK 46
PTZ00119 PTZ00119
40S ribosomal protein S15; Provisional
 3-79 9.71e-04

40S ribosomal protein S15; Provisional


Pssm-ID: 240278  Cd Length: 302  Bit Score: 36.08  E-value: 9.71e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492017277   3 ISKTEKEKIMKEYATHEGDTGSVEVQVALLTADINNLTDHMKSHKHDHHSYVGLLKKIGHRRNLLRYLENNDINRYR 79
Cdd:PTZ00119 105 IHKYKKLCIRRCLQRRPFDTGSAPVQIGCLTEKILNLRAHLILRCKDHPKKRTMSILLARRQKLMKYLYKTDFELYK 181
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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