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Conserved domains on  [gi|500129681|ref|WP_011805686|]
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MULTISPECIES: fluoride efflux transporter CrcB [Diaphorobacter]

Protein Classification

fluoride efflux transporter CrcB( domain architecture ID 10014599)

fluoride efflux transporter CrcB is important for reducing fluoride concentration in the cell, thus reducing its toxicity

Gene Ontology:  GO:0005253|GO:1903425|GO:1903424
PubMed:  27449280|28952925|29393634
TCDB:  1.A.43.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
18-125 7.56e-46

fluoride efflux transporter CrcB;


:

Pssm-ID: 184564  Cd Length: 127  Bit Score: 144.98  E-value: 7.56e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:PRK14196  19 RWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTFSTFSAEVVTLLQEGRFGW 98

                         90       100
                 ....*....|....*....|....*...
gi 500129681  98 ALGLCALHVAGSLCMTWAGLHSLPWLWA 125
Cdd:PRK14196  99 ALLNVALHLLGSLAMTALGFWTFSALAA 126
 
Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
18-125 7.56e-46

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 144.98  E-value: 7.56e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:PRK14196  19 RWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTFSTFSAEVVTLLQEGRFGW 98

                         90       100
                 ....*....|....*....|....*...
gi 500129681  98 ALGLCALHVAGSLCMTWAGLHSLPWLWA 125
Cdd:PRK14196  99 ALLNVALHLLGSLAMTALGFWTFSALAA 126
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 18-117 6.83e-27

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 96.71  E-value: 6.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQ-GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:COG0239   18 RYLLSLLLPRLfGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSPELRLLLGTGFLGGFTTFSTFSLETVRLLERGRYL 97

                         90       100
                 ....*....|....*....|.
gi 500129681  97 QALGLCALHVAGSLCMTWAGL 117
Cdd:COG0239   98 LALLYVLLSVVLGLLAAALGL 118
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 18-115 3.27e-24

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 89.45  E-value: 3.27e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681   18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPqLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:pfam02537  13 RYLLSLLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERG-HSPELRLLLGTGFCGGLTTFSTFSLETLTLLRAGQYLL 91

                          90
                  ....*....|....*...
gi 500129681   98 ALGLCALHVAGSLCMTWA 115
Cdd:pfam02537  92 ALLYVLLSVVLGLAAVVL 109
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 18-116 6.96e-15

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 65.87  E-value: 6.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681   18 RWRLGLWLN--TQGALLPWGTLAANLIGGYLIGLcLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRL 95
Cdd:TIGR00494  14 RYLLGIFISagLFGNSLPLGTLTVNIIGCFGIGF-VTLFTQPAVISPDLKLLIGTGFLGGFTTFSTFSLETTSLLQEGQL 92

                          90       100
                  ....*....|....*....|.
gi 500129681   96 AQALGLCALHVAGSLCMTWAG 116
Cdd:TIGR00494  93 GEAVLYILGTLGGGLIGVALG 113
 
Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
18-125 7.56e-46

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 144.98  E-value: 7.56e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:PRK14196  19 RWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTFSTFSAEVVTLLQEGRFGW 98

                         90       100
                 ....*....|....*....|....*...
gi 500129681  98 ALGLCALHVAGSLCMTWAGLHSLPWLWA 125
Cdd:PRK14196  99 ALLNVALHLLGSLAMTALGFWTFSALAA 126
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 18-117 6.83e-27

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 96.71  E-value: 6.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQ-GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:COG0239   18 RYLLSLLLPRLfGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSPELRLLLGTGFLGGFTTFSTFSLETVRLLERGRYL 97

                         90       100
                 ....*....|....*....|.
gi 500129681  97 QALGLCALHVAGSLCMTWAGL 117
Cdd:COG0239   98 LALLYVLLSVVLGLLAAALGL 118
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 18-115 3.27e-24

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 89.45  E-value: 3.27e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681   18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPqLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:pfam02537  13 RYLLSLLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERG-HSPELRLLLGTGFCGGLTTFSTFSLETLTLLRAGQYLL 91

                          90
                  ....*....|....*...
gi 500129681   98 ALGLCALHVAGSLCMTWA 115
Cdd:pfam02537  92 ALLYVLLSVVLGLAAVVL 109
PRK14234 PRK14234
fluoride efflux transporter CrcB;
35-117 3.91e-16

fluoride efflux transporter CrcB;


Pssm-ID: 172722  Cd Length: 124  Bit Score: 69.03  E-value: 3.91e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  35 GTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGSLCMTW 114
Cdd:PRK14234  37 ATLAVNIVGCLLIGLLYGLFLLRPEVPIELRAGLIVGFLGGLTTFSSFSLDTLRLLESGQVPLALGYAGISVFGGLLATW 116


                 ...
gi 500129681 115 AGL 117
Cdd:PRK14234 117 AGL 119
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 18-116 6.96e-15

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 65.87  E-value: 6.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681   18 RWRLGLWLN--TQGALLPWGTLAANLIGGYLIGLcLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRL 95
Cdd:TIGR00494  14 RYLLGIFISagLFGNSLPLGTLTVNIIGCFGIGF-VTLFTQPAVISPDLKLLIGTGFLGGFTTFSTFSLETTSLLQEGQL 92

                          90       100
                  ....*....|....*....|.
gi 500129681   96 AQALGLCALHVAGSLCMTWAG 116
Cdd:TIGR00494  93 GEAVLYILGTLGGGLIGVALG 113
PRK14195 PRK14195
fluoride efflux transporter CrcB;
18-118 9.47e-14

fluoride efflux transporter CrcB;


Pssm-ID: 184563  Cd Length: 125  Bit Score: 63.13  E-value: 9.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLW-LNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14195  18 RYLVGVGaLRLMGPAFPWGTLAVNVTGSFLIGVLAGLLAHRWNASQEWRLFLIVGVLGGFTTFSAFSLDAALLIERGAYG 97

                         90       100
                 ....*....|....*....|..
gi 500129681  97 QALGLCALHVAGSLCMTWAGLH 118
Cdd:PRK14195  98 AAAAYIAASVVLSVAALFAGLA 119
PRK14223 PRK14223
fluoride efflux transporter CrcB;
32-116 1.57e-13

fluoride efflux transporter CrcB;


Pssm-ID: 184576  Cd Length: 122  Bit Score: 62.39  E-value: 1.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  32 LPWGTLAANLIGGYLIGLCL--ALFQALPqldPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGS 109
Cdd:PRK14223  31 IPTGTLIVNLIGSFILGFLLysSLFGSIS---PEYRLFIITGFCGALTTFSTFSYETFSLLEEGLYIKALLNILLNVFGC 107


                 ....*..
gi 500129681 110 LCMTWAG 116
Cdd:PRK14223 108 LIMIYFG 114
PRK14222 PRK14222
fluoride efflux transporter CrcB;
29-117 9.23e-13

fluoride efflux transporter CrcB;


Pssm-ID: 172710  Cd Length: 124  Bit Score: 60.50  E-value: 9.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14222  30 GRAFPYGTLAVNVIGAFLIGLIMEFSLRSTLIPPTLRIGLTIGFLGGLTTFSTFSYETFRLLEDGELLIASVNVLASVVV 109


                 ....*....
gi 500129681 109 SLCMTWAGL 117
Cdd:PRK14222 110 CLVCTWLGI 118
PRK14212 PRK14212
fluoride efflux transporter CrcB;
29-117 1.23e-12

fluoride efflux transporter CrcB;


Pssm-ID: 184569  Cd Length: 128  Bit Score: 60.21  E-value: 1.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14212  30 GDSFPYGTLIVNCLGCFVLGFLMQWGFSSDSHNTHLKLMLTAGFLGAFTTFSTFSYETLDCFKAGDYFNGFSNILANVLL 109


                 ....*....
gi 500129681 109 SLCMTWAGL 117
Cdd:PRK14212 110 GLLMVFIGA 118
PRK14230 PRK14230
camphor resistance protein CrcB; Provisional
 35-117 1.05e-11

camphor resistance protein CrcB; Provisional


Pssm-ID: 172718  Cd Length: 119  Bit Score: 57.77  E-value: 1.05e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  35 GTLAANLIGGYLIGLCLALFQalpqlDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGSLCMTW 114
Cdd:PRK14230  35 GNLFANWTGALLIGIFAETVN-----HPQWKLLLITGFLGSLTTLSGFSLETVTLLQSNRPASALANIFLHTAGSLLLTW 109


                 ...
gi 500129681 115 AGL 117
Cdd:PRK14230 110 LGL 112
PRK14197 PRK14197
fluoride efflux transporter CrcB;
29-116 1.32e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172685  Cd Length: 124  Bit Score: 57.46  E-value: 1.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQaLPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14197  30 GSSFPFGTLLVNVLGSFLMGVIYALGQ-MSHVSPELKALIGVGLLGALTTFSTFSNETLLLMQEGAWLKAALNVVLNLSL 108


                 ....*...
gi 500129681 109 SLCMTWAG 116
Cdd:PRK14197 109 CLFMVYLG 116
PRK14201 PRK14201
fluoride efflux transporter CrcB;
20-99 1.60e-11

fluoride efflux transporter CrcB;


Pssm-ID: 184566  Cd Length: 121  Bit Score: 57.02  E-value: 1.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  20 RLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQAL 99
Cdd:PRK14201  17 RYLLSFLNTDGGFPIGTLIANLTGAFLMGLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQFELIHMFDHQQFITLL 96
PRK14227 PRK14227
fluoride efflux transporter CrcB;
29-117 2.21e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172715  Cd Length: 124  Bit Score: 56.77  E-value: 2.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14227  30 GLDFPYGTLIVNSVGSFILSFFMILFLEKLSLDPLWRLFVAVGFCGSFTTFSSFTYETIALFQDGDYTKAMLNIILNNVL 109


                 ....*....
gi 500129681 109 SLCMTWAGL 117
Cdd:PRK14227 110 SITSAFSGI 118
PRK14200 PRK14200
fluoride efflux transporter CrcB;
29-120 8.36e-10

fluoride efflux transporter CrcB;


Pssm-ID: 237638  Cd Length: 127  Bit Score: 52.88  E-value: 8.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14200  33 GRGFPYGTLTVNVVGSFIMGLLIAAFENELLATEPWRQIIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGLNVLLNVVL 112

                         90
                 ....*....|..
gi 500129681 109 SLCMTWAGLHSL 120
Cdd:PRK14200 113 SISAAWIGFQLL 124
PRK14202 PRK14202
fluoride efflux transporter CrcB;
18-119 4.83e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172690  Cd Length: 128  Bit Score: 50.87  E-value: 4.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:PRK14202  22 RYLVALALSFIGTGFPFATFTVNLLGSFLIGFISELALSTTLVSPEARLLLVTGFCGGFTTFSSYMYEIAALLRDGELFY 101

                         90       100
                 ....*....|....*....|..
gi 500129681  98 AlglcALHVAGSLCMTWAGLHS 119
Cdd:PRK14202 102 A----SLYLAGSLVGGFVALYS 119
PRK14199 PRK14199
fluoride efflux transporter CrcB;
32-110 1.80e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172687  Cd Length: 128  Bit Score: 49.39  E-value: 1.80e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 500129681  32 LPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGSL 110
Cdd:PRK14199  36 FPYGTLIVNIVGALLIGFIMEFSMDTALISSNMKLFLTTGIMGGLTTFSTFSYETINLITNGNILLGIENIILNLGLSL 114
PRK14216 PRK14216
fluoride efflux transporter CrcB;
33-110 2.67e-08

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 49.07  E-value: 2.67e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 500129681  33 PWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGSL 110
Cdd:PRK14216  38 PWPTFTVNVVGAFLLGYFTTRLLERLPLSSYRRPLLGTGLCGGLTTFSTMQVETIRMIEHGHWGLAAGYTAASIAAGL 115
PRK14215 PRK14215
fluoride efflux transporter CrcB;
18-123 3.54e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172703  Cd Length: 126  Bit Score: 48.67  E-value: 3.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQ-GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14215  18 RYGIGLWAAQRwGTSWPYGTFIINLLGCLLIGLLLTLATTRLTLSEPARLMLVTGLLGGFTTFSTFGYESYSLLSSGNWL 97

                         90       100
                 ....*....|....*....|....*..
gi 500129681  97 QALGLCALHVAGSLCMTWAGLHSLPWL 123
Cdd:PRK14215  98 AAGGYVVGSVGGGLIAVIIGAGLGRWL 124
PRK14217 PRK14217
fluoride efflux transporter CrcB;
26-116 5.76e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172705  Cd Length: 134  Bit Score: 48.08  E-value: 5.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  26 NTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALH 105
Cdd:PRK14217  29 NAWGIKFPYGTLLVNTLGSFLAGFFLIVLVGRFSAEESFRLFLFTGFLGAFTTFSSFAAESLFMFEQGYWFKLITNILVN 108

                         90
                 ....*....|.
gi 500129681 106 VAGSLCMTWAG 116
Cdd:PRK14217 109 NVGSLSMVFIG 119
PRK14213 PRK14213
camphor resistance protein CrcB; Provisional
 27-116 8.94e-08

camphor resistance protein CrcB; Provisional


Pssm-ID: 184570  Cd Length: 118  Bit Score: 47.12  E-value: 8.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  27 TQGALLPWGTLAANLIGGYLIGLclalFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHV 106
Cdd:PRK14213  28 TKGLSLPIGIMTVNILGSFGLGI----FTGLGVDNASVSIIIGTGFFGAFTTFSTFSVEAVQLLMAKRVKESILYIALTL 103

                         90
                 ....*....|
gi 500129681 107 AGSLCMTWAG 116
Cdd:PRK14213 104 AGSLLAFWCG 113
PRK14208 PRK14208
fluoride efflux transporter CrcB;
29-123 1.08e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172696  Cd Length: 126  Bit Score: 47.26  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAG 108
Cdd:PRK14208  30 GPDFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPDLRLFLAAGVMGGFTTYSSFNYETLALLEQGRLAAAAAYLLATVLG 109

                         90
                 ....*....|....*
gi 500129681 109 SLCMTWAGLHSLPWL 123
Cdd:PRK14208 110 CLAAAFAATLLVRWL 124
PRK14224 PRK14224
fluoride efflux transporter CrcB;
33-89 1.12e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237642  Cd Length: 126  Bit Score: 47.08  E-value: 1.12e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 500129681  33 PWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGL 89
Cdd:PRK14224  35 QLGTLSVNVLGSFMLGMIMYDTEYIGFIGPKGRLAFGTGFLGAFTTFSTFAVQSFSM 91
PRK14198 PRK14198
fluoride efflux transporter CrcB;
29-117 1.41e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172686  Cd Length: 124  Bit Score: 46.66  E-value: 1.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQqrlaQALGLCALHVAG 108
Cdd:PRK14198  29 GTSFPYGTFIINVSGSLVMGLIAGYLAFKGGAPQHWRLFLMTGILGGYTTFSAFSLDAALLYER----GALGLAALYVLG 104


                 ....*....
gi 500129681 109 SLCMTWAGL 117
Cdd:PRK14198 105 SVALGIAGL 113
PRK14207 PRK14207
fluoride efflux transporter CrcB;
33-99 1.62e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172695  Cd Length: 123  Bit Score: 46.66  E-value: 1.62e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 500129681  33 PWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQAL 99
Cdd:PRK14207  34 PVGTLLVNSIASFILGYLYGLLFWGFDVSPEWRAFLGTGFCGGLSTFSTFSYETFSLLREREYLLAL 100
PRK14229 PRK14229
fluoride efflux transporter CrcB;
28-94 2.01e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172717  Cd Length: 108  Bit Score: 45.98  E-value: 2.01e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 500129681  28 QGALLPWGTLAANLIGGYLIGLCLALFQalpqlDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQR 94
Cdd:PRK14229  24 QASKLPLGTLIANLLGCFLIGVFYNHVE-----SKEVYAILATGFCGGLTTFSTLNDELQRLLSDKK 85
PRK14206 PRK14206
fluoride efflux transporter CrcB;
19-116 2.38e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172694  Cd Length: 127  Bit Score: 46.34  E-value: 2.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  19 WRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQL--DPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14206  19 WLSGLVAEATGGTFPWGTLVINVSGSFLIGFFATLTGPEGRVfvGESWRLFVMVGVCGGFTTFSSFSLQTLNLARDGDWL 98

                         90       100
                 ....*....|....*....|
gi 500129681  97 QALGLCALHVAGSLCMTWAG 116
Cdd:PRK14206  99 RAGGNVVLSVVFCLLAVWLG 118
PRK14231 PRK14231
fluoride efflux transporter CrcB;
18-112 2.85e-07

fluoride efflux transporter CrcB;


Pssm-ID: 184579  Cd Length: 129  Bit Score: 46.00  E-value: 2.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNtqGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQ 97
Cdd:PRK14231  17 RYAMNLWLG--GGDFPSATLAVNLIGCFLLAFLMQFLAEKSRISLVILNGIGTGFIGAFTTFSAFSVDTIQLVQSGAWLL 94

                         90
                 ....*....|....*
gi 500129681  98 ALGLCALHVAGSLCM 112
Cdd:PRK14231  95 AVSYVLASFIGGLIM 109
PRK14218 PRK14218
fluoride efflux transporter CrcB;
29-130 3.29e-06

fluoride efflux transporter CrcB;


Pssm-ID: 184573  Cd Length: 133  Bit Score: 43.34  E-value: 3.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRlaqalglcALHVAG 108
Cdd:PRK14218  36 GAGFPWGTLAVNLIGSFVAGFLLIWLDKRGSAGWPWRMLLIVGLIGGLTTFSSLMMECLVFVRSDR--------SLMVGI 107

                         90       100
                 ....*....|....*....|..
gi 500129681 109 SLCMTWagLHSLPWLWAGARQG 130
Cdd:PRK14218 108 YLCITL--LFGLLFVFLGARLG 127
PRK14211 PRK14211
fluoride efflux transporter CrcB;
32-117 5.74e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172699  Cd Length: 114  Bit Score: 42.23  E-value: 5.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  32 LPWGTLAANLIGGYLIGLCLAlfqalPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVAGSLC 111
Cdd:PRK14211  30 FPVATFLVNVAGCLILGLLSG-----ASLSTQTFALLGTGFCGGLTTYSTFAVESVGLLRIRQALLSVVYIVASVAAGLA 104


                 ....*.
gi 500129681 112 MTWAGL 117
Cdd:PRK14211 105 AAWLGF 110
PRK14226 PRK14226
fluoride efflux transporter CrcB;
32-118 7.54e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172714  Cd Length: 130  Bit Score: 42.56  E-value: 7.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  32 LPWGTLAANLIGGYLIGLCLALFQALP----QLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQALGLCALHVA 107
Cdd:PRK14226  33 IPLGILLCNIIGSLIIGMMAAFLIETKlfneDVSTYVRFLLVTGFLGGFTTFSSFSLDILNLLQRGEIFIAIGYIMVSVL 112

                         90
                 ....*....|.
gi 500129681 108 GSLCMTWAGLH 118
Cdd:PRK14226 113 ASLIAVILGFY 123
PRK14233 PRK14233
fluoride efflux transporter CrcB;
29-99 1.85e-05

fluoride efflux transporter CrcB;


Pssm-ID: 172721  Cd Length: 133  Bit Score: 41.41  E-value: 1.85e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500129681  29 GALLPWGTLAANLIGGYLIGLCLALFQALPQL--DPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLAQAL 99
Cdd:PRK14233  32 GETFPWGTFVVNVSGAFVIGTAAGLGARLGGIfsTTIFHEFIMVGLLGGYTTVSSFCLQSVNLMLDGEQRQAL 104
PRK14210 PRK14210
fluoride efflux transporter CrcB;
27-91 7.56e-05

fluoride efflux transporter CrcB;


Pssm-ID: 172698  Cd Length: 127  Bit Score: 39.60  E-value: 7.56e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500129681  27 TQGALLPWGTLAANLIGGYLIGLCLALFQALpQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQ 91
Cdd:PRK14210  31 PALFPFPWGTFAVNIIGSLLIGFFYSFSERF-NLSFELRLFLTVGFCGGFTTFSTLANDSLSLLK 94
PRK14220 PRK14220
fluoride efflux transporter CrcB;
28-91 2.64e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237641  Cd Length: 120  Bit Score: 38.22  E-value: 2.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500129681  28 QGALLPWGTLAANLIGGYLIGLCLALfqalpQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQ 91
Cdd:PRK14220  30 QFSNLPTPTLLINLTGAFILGLIFGR-----KFNPFIYALLGTGVLGGYTTFSTLNTELVSLYK 88
PRK14214 PRK14214
fluoride efflux transporter CrcB;
32-89 2.84e-04

fluoride efflux transporter CrcB;


Pssm-ID: 184571  Cd Length: 118  Bit Score: 37.92  E-value: 2.84e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 500129681  32 LPWGTLAANLIGGYLIGlclalFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGL 89
Cdd:PRK14214  34 FPYATFFINITGSFLLG-----FLVSSALGPVWQLFLGTGFMGGYTTFSTFKVESMEL 86
PRK14209 PRK14209
fluoride efflux transporter CrcB;
29-117 2.85e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237640  Cd Length: 124  Bit Score: 38.00  E-value: 2.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  29 GALLPWGTLAANLIGGYLIGLclaLFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRlaqaLGLCALHVAG 108
Cdd:PRK14209  31 GPAFPVGTMIVNVVGSFLMGV---LVVVLAHKGNRYAPFLMTGMLGGFTTFSAFSLDAVTLYERGQ----AGLAAAYVGL 103


                 ....*....
gi 500129681 109 SLCMTWAGL 117
Cdd:PRK14209 104 SVGLSLAGL 112
PRK14205 PRK14205
fluoride efflux transporter CrcB;
33-95 3.72e-04

fluoride efflux transporter CrcB;


Pssm-ID: 172693  Cd Length: 118  Bit Score: 37.47  E-value: 3.72e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500129681  33 PWGTLAANLIGGYLIGLCLAlfqalPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRL 95
Cdd:PRK14205  34 PIATFLINITGAFLLGYIIG-----NGVTTGWQLLLGTGFMGAFTTFSTFKLESVQLLNRKNF 91
ccrB PRK01636
fluoride efflux transporter CrcB;
33-121 5.30e-04

fluoride efflux transporter CrcB;


Pssm-ID: 179312  Cd Length: 118  Bit Score: 37.05  E-value: 5.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  33 PWGTLAANLIGGYLIGLCLALFQaLPQLDPVWRALLITGFLGALTTFSTFsaeVVGLLQQQRLAQALGLCALHVAGSL-- 110
Cdd:PRK01636  18 PLDIFVANVVAAFLLGLTTSLHK-RDKISQYVHLMIGTGIMGGLSTFSSF---VYGAVEMAKSPGEVLVSICYLVASLiv 93

                         90
                 ....*....|...
gi 500129681 111 --CMTWAGLHSLP 121
Cdd:PRK01636  94 gyIAVELGLMIGK 106
PRK14203 PRK14203
fluoride efflux transporter CrcB;
19-100 5.72e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237639  Cd Length: 132  Bit Score: 37.48  E-value: 5.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  19 WRLGLWLNTQGALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALL--ITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14203  24 FLSGLVARRIGETFPWGTLTVNVSGAFAIGIFGALAASGHGLFALPAPWLfaVTGFLGCYTTVSSFSLQTLTLARDGEFL 103


                 ....
gi 500129681  97 QALG 100
Cdd:PRK14203 104 RALG 107
PRK14232 PRK14232
fluoride efflux transporter CrcB;
18-99 6.53e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237644  Cd Length: 120  Bit Score: 37.07  E-value: 6.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQGA-LLPWGTLAANLIGGYLIGLCLALfqalpQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14232  17 RYQLGKVISKKSKsTFPVGTFIINITGAILLGIVSSS-----NISKNMYLLLGDGFLGAYTTFSTFMYEGFNLFQEKEKL 91


                 ...
gi 500129681  97 QAL 99
Cdd:PRK14232  92 NAF 94
PRK14219 PRK14219
fluoride efflux transporter CrcB;
18-116 1.46e-03

fluoride efflux transporter CrcB;


Pssm-ID: 172707  Cd Length: 132  Bit Score: 36.36  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500129681  18 RWRLGLWLNTQ-GALLPWGTLAANLIGGYLIGLCLALFQALPQLDPVWRALLITGFLGALTTFSTFSAEVVGLLQQQRLA 96
Cdd:PRK14219  17 RYYLGLTIHEFwHHTFPLATLLINLAGCFLLAWLTTYIAKLNILPSDVITGIGTGFIGSFTTFSTFSVETIQLINHSEWS 96

                         90       100
                 ....*....|....*....|
gi 500129681  97 QALGLCALHVAGSLCMTWAG 116
Cdd:PRK14219  97 IAFLYVSCSILGGLIMSGLG 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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