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Conserved domains on  [gi|505049406|ref|WP_015236508|]
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LutB/LldF family L-lactate oxidation iron-sulfur protein [Deinococcus peraridilitoris]

Protein Classification

lactate utilization protein B( domain architecture ID 11439020)

lactate utilization protein B (LutB) is an iron-sulfur cluster-binding protein involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source

Gene Ontology:  GO:0051539|GO:0046872

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LutB COG1139
L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and ...
 6-461 0e+00

L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and conversion];


:

Pssm-ID: 440754 [Multi-domain]  Cd Length: 465  Bit Score: 715.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   6 RRFPEAHRRALLNREVRGATFRATENFNLKRGLAYGELRALDDLKSYAAAVKDHTLANLDLYLAQLTEHIERLGGHVHFA 85
Cdd:COG1139    7 EDFKERAREALADEQLRKALDRATDTLRAKRAKAVAELPDWEALREAARAIKDHALANLDEYLEQFEANATANGGHVHWA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  86 ADAQEAREIVVRIARETNCRSAVKSKSMVSEEIELNAALEAAGVRPVETDLGEYILQQEGEFPSHIIGPAIHKPKREVDE 165
Cdd:COG1139   87 RDAEEANRIVLDIAREKGAKKVVKSKSMVTEEIGLNEALEAAGIEVVETDLGEYIVQLAGEPPSHIVMPAIHKNREQIAE 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 166 LFWRLHGVPRGTS-ADGLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTTSAPRVHVAVMGIEKVIP 244
Cdd:COG1139  167 LFHEKLGTEPLTDdPEELTRAAREHLREKFLEADVGITGANFAVAETGTIVLVTNEGNARLCTTLPKVHIAVMGIEKLVP 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 245 RLSDLGVFLKLLPRAATGQRASVFVSVISGPKRPEESEGPQEFHLVVLDNGRSRILADPEMRASLRCIRCGACLNTCPVY 324
Cdd:COG1139  247 TLEDLEVFLRLLPRSATGQRITTYTSLITGPRRPGEGDGPEEFHLVLLDNGRSAMLADPEFREALRCIRCGACLNVCPVY 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 325 QQLGGHAYGWVYSGPIGSVLDPNLLGLKEAGSLPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALAMRS 404
Cdd:COG1139  327 RRVGGHAYGSVYPGPIGAVLTPLLHGLEKAADLPYASTLCGACTEVCPVKIPIPELLLELRERIVEEGLTPPAEKLAMKA 406

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505049406 405 FAQVMTRPRIYRLASRGARFS--PWRGGRLPRLNLPLLAGWQLGRDFPAPARQGFRDLW 461
Cdd:COG1139  407 WAWVMSNPKLYRLALRLARRAlkLLPRGGGIRRLPGPLGGWTKGRDLPAPAKESFRDWW 465
 
Name Accession Description Interval E-value
LutB COG1139
L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and ...
 6-461 0e+00

L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and conversion];


Pssm-ID: 440754 [Multi-domain]  Cd Length: 465  Bit Score: 715.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   6 RRFPEAHRRALLNREVRGATFRATENFNLKRGLAYGELRALDDLKSYAAAVKDHTLANLDLYLAQLTEHIERLGGHVHFA 85
Cdd:COG1139    7 EDFKERAREALADEQLRKALDRATDTLRAKRAKAVAELPDWEALREAARAIKDHALANLDEYLEQFEANATANGGHVHWA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  86 ADAQEAREIVVRIARETNCRSAVKSKSMVSEEIELNAALEAAGVRPVETDLGEYILQQEGEFPSHIIGPAIHKPKREVDE 165
Cdd:COG1139   87 RDAEEANRIVLDIAREKGAKKVVKSKSMVTEEIGLNEALEAAGIEVVETDLGEYIVQLAGEPPSHIVMPAIHKNREQIAE 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 166 LFWRLHGVPRGTS-ADGLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTTSAPRVHVAVMGIEKVIP 244
Cdd:COG1139  167 LFHEKLGTEPLTDdPEELTRAAREHLREKFLEADVGITGANFAVAETGTIVLVTNEGNARLCTTLPKVHIAVMGIEKLVP 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 245 RLSDLGVFLKLLPRAATGQRASVFVSVISGPKRPEESEGPQEFHLVVLDNGRSRILADPEMRASLRCIRCGACLNTCPVY 324
Cdd:COG1139  247 TLEDLEVFLRLLPRSATGQRITTYTSLITGPRRPGEGDGPEEFHLVLLDNGRSAMLADPEFREALRCIRCGACLNVCPVY 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 325 QQLGGHAYGWVYSGPIGSVLDPNLLGLKEAGSLPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALAMRS 404
Cdd:COG1139  327 RRVGGHAYGSVYPGPIGAVLTPLLHGLEKAADLPYASTLCGACTEVCPVKIPIPELLLELRERIVEEGLTPPAEKLAMKA 406

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505049406 405 FAQVMTRPRIYRLASRGARFS--PWRGGRLPRLNLPLLAGWQLGRDFPAPARQGFRDLW 461
Cdd:COG1139  407 WAWVMSNPKLYRLALRLARRAlkLLPRGGGIRRLPGPLGGWTKGRDLPAPAKESFRDWW 465
TIGR00273 TIGR00273
iron-sulfur cluster-binding protein; Members of this family have a perfect 4Fe-4S binding ...
 21-450 1.90e-157

iron-sulfur cluster-binding protein; Members of this family have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4fe-4S iron-sulfur clusters. [Energy metabolism, Electron transport]


Pssm-ID: 129374 [Multi-domain]  Cd Length: 432  Bit Score: 453.56  E-value: 1.90e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   21 VRGATFRATENFNLKRGLAYGELRALDDLKSYAAAVKDHTLANLDLYLAQLTEHIERLGGHVHFAADAQEAREIVVRIAR 100
Cdd:TIGR00273   6 LREALRNAQERLRANRKLLVEELGYWEEWRELVKEIKLKVLENLDFYLDQLKENVTQRGGHVYYAKTAEEARKIIGKVAQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  101 ETNCRSAVKSKSMVSEEIELNAALEAAGVRPVETDLGEYILQQEGEFPSHIIGPAIHKPKREVDELFWRLHGVPRGTSAD 180
Cdd:TIGR00273  86 EKNGKKVVKSKSMVSEEIGLNEVLEKIGIEVWETDLGELILQLDGDPPSHIVVPALHKNRQQIGEILKERLGYEGEESPE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  181 GLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTTSAPRVHVAVMGIEKVIPRLSDLGVFLKLLPRAA 260
Cdd:TIGR00273 166 VLAREARKFMREKFLSADIGISGCNFAIAETGSIFLVENEGNGRLSTTLPKTHIAVMGIEKIVPTFDDELVLKSMLARSA 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  261 TGQRASVFVSVISGPKRPEESEGPQEFHLVVLDNGRSRILADpEMRASLRCIRCGACLNTCPVYQQLGGHAYGWVYSGPI 340
Cdd:TIGR00273 246 VGTRLTAYINVLTGPRQEGDVDGPEEFHLILLDNGRSNILAT-EFREVLACIRCGACQNECPVYRHIGGHWYGSIYPGPI 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  341 GSVLDPNLLGLKEAGSLPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALAMRSFAQVMTRPRIYRLASR 420
Cdd:TIGR00273 325 GAVWSPLLGGYTDYKHLPYLSSLCGACREVCPVKIPLPELIREHRSDKVEKGRHSGMEKLAMKMFAKMASDGALWKFGLK 404

                         410       420       430
                  ....*....|....*....|....*....|
gi 505049406  421 GArfSPWRGGRLPRLNLPLLAGWQLGRDFP 450
Cdd:TIGR00273 405 MA--QFFSPLGKLLAPIGPVKEWASVRDLP 432
LUD_dom pfam02589
LUD domain; This entry represents a domain found in lactate utilization proteins B (LutB) and ...
 68-292 2.64e-54

LUD domain; This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate


Pssm-ID: 426855  Cd Length: 188  Bit Score: 180.12  E-value: 2.64e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   68 LAQLTEHIERLGGHVHFAADAQEAREIVVRIARETNcrsavksksmvseeielnaaleaAGVRPVETDLGEYIlqqegef 147
Cdd:pfam02589   1 LEEFKENLEANGAEVYYAKTAEEALEYILELIKEGG-----------------------VVSEGGSTDLGELG------- 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  148 pshiIGPAIHKPKREVDELFwrlhgvprgtsADGLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTT 227
Cdd:pfam02589  51 ----LAPALHSGRYEVLDLF-----------EEKLTAEAREELREKALTADVGITGANFAIAETGTLVLVDGEGNRRLLS 115

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406  228 SAPRVHVAVMGIEKVIPRLSDLGVFLKLLPRAATGQRASVFVSVISGPKRPEESE--------GPQEFHLVVL 292
Cdd:pfam02589 116 FLPKVHIAVVGINKIVPDLEDAVKRLRLAPRNATRQKLTPYITFISGPSRTADIElvlvvgvhGPGELHVILV 188
PRK09326 PRK09326
F420H2 dehydrogenase subunit F; Provisional
 311-373 1.86e-04

F420H2 dehydrogenase subunit F; Provisional


Pssm-ID: 181779 [Multi-domain]  Cd Length: 341  Bit Score: 43.67  E-value: 1.86e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406 311 CIRCGACLNTCPVyqqlgghayGWVYSGPIGSVLDPNLLGLKEAGSLPYASTLCGACGDVCPV 373
Cdd:PRK09326  14 CTACGACEAVCPI---------GAITVDKKAEIRDPNDLELYEKGAAPNVCEGCLTCSRICPV 67
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 310-372 2.13e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 38.78  E-value: 2.13e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505049406 310 RCIRCGACLNTCPvYQ--QLGGHAYGWvySGPIGSVLDPNLlglkeagslpYASTLCG-ACGDVCP 372
Cdd:cd16373   15 LCIRCGLCVEACP-TGviQPAGLEDGL--EGGRTPYLDPRE----------GPCDLCCdACVEVCP 67
 
Name Accession Description Interval E-value
LutB COG1139
L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and ...
 6-461 0e+00

L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and conversion];


Pssm-ID: 440754 [Multi-domain]  Cd Length: 465  Bit Score: 715.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   6 RRFPEAHRRALLNREVRGATFRATENFNLKRGLAYGELRALDDLKSYAAAVKDHTLANLDLYLAQLTEHIERLGGHVHFA 85
Cdd:COG1139    7 EDFKERAREALADEQLRKALDRATDTLRAKRAKAVAELPDWEALREAARAIKDHALANLDEYLEQFEANATANGGHVHWA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  86 ADAQEAREIVVRIARETNCRSAVKSKSMVSEEIELNAALEAAGVRPVETDLGEYILQQEGEFPSHIIGPAIHKPKREVDE 165
Cdd:COG1139   87 RDAEEANRIVLDIAREKGAKKVVKSKSMVTEEIGLNEALEAAGIEVVETDLGEYIVQLAGEPPSHIVMPAIHKNREQIAE 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 166 LFWRLHGVPRGTS-ADGLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTTSAPRVHVAVMGIEKVIP 244
Cdd:COG1139  167 LFHEKLGTEPLTDdPEELTRAAREHLREKFLEADVGITGANFAVAETGTIVLVTNEGNARLCTTLPKVHIAVMGIEKLVP 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 245 RLSDLGVFLKLLPRAATGQRASVFVSVISGPKRPEESEGPQEFHLVVLDNGRSRILADPEMRASLRCIRCGACLNTCPVY 324
Cdd:COG1139  247 TLEDLEVFLRLLPRSATGQRITTYTSLITGPRRPGEGDGPEEFHLVLLDNGRSAMLADPEFREALRCIRCGACLNVCPVY 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 325 QQLGGHAYGWVYSGPIGSVLDPNLLGLKEAGSLPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALAMRS 404
Cdd:COG1139  327 RRVGGHAYGSVYPGPIGAVLTPLLHGLEKAADLPYASTLCGACTEVCPVKIPIPELLLELRERIVEEGLTPPAEKLAMKA 406

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505049406 405 FAQVMTRPRIYRLASRGARFS--PWRGGRLPRLNLPLLAGWQLGRDFPAPARQGFRDLW 461
Cdd:COG1139  407 WAWVMSNPKLYRLALRLARRAlkLLPRGGGIRRLPGPLGGWTKGRDLPAPAKESFRDWW 465
TIGR00273 TIGR00273
iron-sulfur cluster-binding protein; Members of this family have a perfect 4Fe-4S binding ...
 21-450 1.90e-157

iron-sulfur cluster-binding protein; Members of this family have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4fe-4S iron-sulfur clusters. [Energy metabolism, Electron transport]


Pssm-ID: 129374 [Multi-domain]  Cd Length: 432  Bit Score: 453.56  E-value: 1.90e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   21 VRGATFRATENFNLKRGLAYGELRALDDLKSYAAAVKDHTLANLDLYLAQLTEHIERLGGHVHFAADAQEAREIVVRIAR 100
Cdd:TIGR00273   6 LREALRNAQERLRANRKLLVEELGYWEEWRELVKEIKLKVLENLDFYLDQLKENVTQRGGHVYYAKTAEEARKIIGKVAQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  101 ETNCRSAVKSKSMVSEEIELNAALEAAGVRPVETDLGEYILQQEGEFPSHIIGPAIHKPKREVDELFWRLHGVPRGTSAD 180
Cdd:TIGR00273  86 EKNGKKVVKSKSMVSEEIGLNEVLEKIGIEVWETDLGELILQLDGDPPSHIVVPALHKNRQQIGEILKERLGYEGEESPE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  181 GLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTTSAPRVHVAVMGIEKVIPRLSDLGVFLKLLPRAA 260
Cdd:TIGR00273 166 VLAREARKFMREKFLSADIGISGCNFAIAETGSIFLVENEGNGRLSTTLPKTHIAVMGIEKIVPTFDDELVLKSMLARSA 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  261 TGQRASVFVSVISGPKRPEESEGPQEFHLVVLDNGRSRILADpEMRASLRCIRCGACLNTCPVYQQLGGHAYGWVYSGPI 340
Cdd:TIGR00273 246 VGTRLTAYINVLTGPRQEGDVDGPEEFHLILLDNGRSNILAT-EFREVLACIRCGACQNECPVYRHIGGHWYGSIYPGPI 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  341 GSVLDPNLLGLKEAGSLPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALAMRSFAQVMTRPRIYRLASR 420
Cdd:TIGR00273 325 GAVWSPLLGGYTDYKHLPYLSSLCGACREVCPVKIPLPELIREHRSDKVEKGRHSGMEKLAMKMFAKMASDGALWKFGLK 404

                         410       420       430
                  ....*....|....*....|....*....|
gi 505049406  421 GArfSPWRGGRLPRLNLPLLAGWQLGRDFP 450
Cdd:TIGR00273 405 MA--QFFSPLGKLLAPIGPVKEWASVRDLP 432
LUD_dom pfam02589
LUD domain; This entry represents a domain found in lactate utilization proteins B (LutB) and ...
 68-292 2.64e-54

LUD domain; This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate


Pssm-ID: 426855  Cd Length: 188  Bit Score: 180.12  E-value: 2.64e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406   68 LAQLTEHIERLGGHVHFAADAQEAREIVVRIARETNcrsavksksmvseeielnaaleaAGVRPVETDLGEYIlqqegef 147
Cdd:pfam02589   1 LEEFKENLEANGAEVYYAKTAEEALEYILELIKEGG-----------------------VVSEGGSTDLGELG------- 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  148 pshiIGPAIHKPKREVDELFwrlhgvprgtsADGLARKAREVIREEFLAADMGISGVNFAVAESGSVVIVENEGNARLTT 227
Cdd:pfam02589  51 ----LAPALHSGRYEVLDLF-----------EEKLTAEAREELREKALTADVGITGANFAIAETGTLVLVDGEGNRRLLS 115

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406  228 SAPRVHVAVMGIEKVIPRLSDLGVFLKLLPRAATGQRASVFVSVISGPKRPEESE--------GPQEFHLVVL 292
Cdd:pfam02589 116 FLPKVHIAVVGINKIVPDLEDAVKRLRLAPRNATRQKLTPYITFISGPSRTADIElvlvvgvhGPGELHVILV 188
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 310-375 2.42e-14

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 67.72  E-value: 2.42e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505049406  310 RCIRCGACLNTCPVYQQLGGHAYGWVYSGPIGSVLDpnLLGLKEAGSLPYASTLCGACGDVCPVRI 375
Cdd:pfam13183   1 RCIRCGACLAACPVYLVTGGRFPGDPRGGAAALLGR--LEALEGLAEGLWLCTLCGACTEVCPVGI 64
LutC COG1556
L-lactate utilization protein LutC, contains LUD domain [Energy production and conversion];
68-293 1.78e-10

L-lactate utilization protein LutC, contains LUD domain [Energy production and conversion];


Pssm-ID: 441165  Cd Length: 206  Bit Score: 60.26  E-value: 1.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  68 LAQLTEHIERLGGHVHFAADAQEAREIVVRIARETNCrsavksKSMVSEEIELNAALEAAGvrpvetdlgeyilqqegef 147
Cdd:COG1556   39 VELFVERLEAVGGEVVRVTTEAELPAALAELLAEAGL------KRIVVPEPGLPAALQLAW------------------- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 148 pshiigpaihkpkREVDELFWRlhgvprgtsadglarkarevirEEFLAADMGISGVNFAVAESGSVVIVENEGNARLTT 227
Cdd:COG1556   94 -------------DPLEELEDP----------------------AALEDADVGITGAEFGIAETGTIVLDSGPDQGRALS 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505049406 228 SAPRVHVAVMGIEKVIPRLSDLgvfLKLLPRAATGQRASVFvsvISGPKR---PEES-----EGPQEFHLVVLD 293
Cdd:COG1556  139 LLPEHHIVVVPASQIVPTMHEA---YARLREKAGLPRNITF---ISGPSKtadIEQTlvlgaHGPRRLHVILVE 206
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 274-408 4.42e-10

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 61.63  E-value: 4.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 274 GPKRPEESEGPQEFHLVVLDNGRSRILADPEMRASL-RCIRCGACLNTCPVYQQLG-------GHAYGW--VYSGPIGSV 343
Cdd:COG0247   42 PGKIGLLNPGVELLGDGDLHDKNLKTLPWKELLDALdACVGCGFCRAMCPSYKATGdekdsprGRINLLreVLEGELPLD 121

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505049406 344 LDPNllgLKEAgslPYASTLCGACGDVCPVRIPLPQMLVTLRGRAVEAGLTSRGEALaMRSFAQV 408
Cdd:COG0247  122 LSEE---VYEV---LDLCLTCKACETACPSGVDIADLIAEARAQLVERGGRPLRDRL-LRTFPDR 179
LutB_C pfam11870
Lactate utilization protein B, C-terminal; This domain is functionally uncharacterized. This ...
 384-466 8.30e-10

Lactate utilization protein B, C-terminal; This domain is functionally uncharacterized. This domain is found at the C-terminal of a family of 4Fe-4S, iron-sulphur cluster binding proteins, including Lactate utilization protein B (LutB). These proteins have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4Fe-4S iron-sulphur clusters. This domain is found in LutB proteins in association with the LUD domain (pfam02589) and usually Fer4_8 (pfam13183). The LutABC operon is involved in lactate-utilization and is essential.


Pssm-ID: 432147 [Multi-domain]  Cd Length: 86  Bit Score: 55.36  E-value: 8.30e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  384 LRGRAVEAG---------LTSRGEALAMRSFAQVMTRPRIYR----LASRGARFSPWRGGrlprlnlpllaGWQLGRDFP 450
Cdd:pfam11870   2 LRHEPVGQGpgvikgqgaKRSAAERLAWKGFALAASSPGLYRlgtwLATRFRGLLPSKLK-----------AWTRVRTFP 70

                          90
                  ....*....|....*.
gi 505049406  451 APARQGFRDLWASRLQ 466
Cdd:pfam11870  71 KPAARSLHDLAKERGV 86
HdrC COG1150
Heterodisulfide reductase, subunit C [Energy production and conversion];
310-390 1.91e-06

Heterodisulfide reductase, subunit C [Energy production and conversion];


Pssm-ID: 440764 [Multi-domain]  Cd Length: 79  Bit Score: 45.66  E-value: 1.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 310 RCIRCGACLNTCPVyqqlgGHAYGwvysgpigsvLDPN------LLGLKEA---GSLPYASTLCGACGDVCPVRIPLPQM 380
Cdd:COG1150    4 KCYQCGTCTASCPV-----ARAMD----------YNPRkiirlaQLGLKEEvlkSDSIWLCVSCYTCTERCPRGIDIADV 68

                         90
                 ....*....|
gi 505049406 381 LVTLRGRAVE 390
Cdd:COG1150   69 MDALRNLAIR 78
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 310-373 8.21e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 43.54  E-value: 8.21e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505049406 310 RCIRCGACLNTCPVyqqlggHAYGWVYSGPIGSVLDpnllglkeagslPYASTLCGACGDVCPV 373
Cdd:COG1146    9 KCIGCGACVEVCPV------DVLELDEEGKKALVIN------------PEECIGCGACELVCPV 54
Fer4_17 pfam13534
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 310-372 1.12e-05

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 433287 [Multi-domain]  Cd Length: 61  Bit Score: 42.83  E-value: 1.12e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406  310 RCIRCGACLNTCPVYQQLGGHAYGWVYSgpigsvLDPNLLGLKEAGSLPYASTLCGACGDVCP 372
Cdd:pfam13534   1 RCIQCGCCVDECPRYLLNGDEPKKLMRA------AYLGDLEELQANKVANLCSECGLCEYACP 57
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 311-375 2.77e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 41.36  E-value: 2.77e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505049406  311 CIRCGACLNTCPVyqqlggHAYGWVYSGPIGsvldpnllGLKEAGSLPYASTLCGACGDVCPVRI 375
Cdd:pfam12838   1 CIGCGACVAACPV------GAITLDEVGEKK--------GTKTVVIDPERCVGCGACVAVCPTGA 51
rnfC TIGR01945
electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in ...
 295-379 4.26e-05

electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273888 [Multi-domain]  Cd Length: 435  Bit Score: 45.80  E-value: 4.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  295 GRSRILA--------DPEMRaslrCIRCGACLNTCPVY---QQLGGHAYGWVYSGpigsVLDPNLLGLKEagslpyastl 363
Cdd:TIGR01945 345 GTSGILAldkeetpeSPEKP----CIRCGKCVQVCPMNllpQQLNWLALADEFDE----AEEHNLMDCIE---------- 406

                          90
                  ....*....|....*.
gi 505049406  364 CGACGDVCPVRIPLPQ 379
Cdd:TIGR01945 407 CGCCSYVCPSNIPLVQ 422
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 298-372 4.39e-05

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 41.08  E-value: 4.39e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505049406  298 RILADPEmraslRCIRCGACLNTCPVYQQLGGHAYGWVYSGPIGSVldpnllglkeagslPYASTLCGACGDVCP 372
Cdd:pfam13237   1 KVVIDPD-----KCIGCGRCTAACPAGLTRVGAIVERLEGEAVRIG--------------VWKCIGCGACVEACP 56
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 311-377 6.30e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 45.13  E-value: 6.30e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505049406 311 CIRCGACLNTCPVY---QQLGGHAygwvysgpigsvldpnllglkEAGSLPYASTL-------CGACGDVCPVRIPL 377
Cdd:COG4656  366 CIRCGRCVDACPMGllpQQLYWYA---------------------RAGDFDKAEEYnlmdcieCGCCSYVCPSKIPL 421
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 287-373 9.10e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 40.80  E-value: 9.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 287 FHLVVLDNGRS--RILADPEmraslRCIRCGACLNTCPVyqqlggHAygwVYSGPIGSVLDPNLlglkeagslpyaSTLC 364
Cdd:COG4231    3 ITVKILDNRTTamRYVIDED-----KCTGCGACVKVCPA------DA---IEEGDGKAVIDPDL------------CIGC 56


                 ....*....
gi 505049406 365 GACGDVCPV 373
Cdd:COG4231   57 GSCVQVCPV 65
SdhB/FrdB COG0479
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and ...
 299-391 1.51e-04

Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440247 [Multi-domain]  Cd Length: 230  Bit Score: 43.20  E-value: 1.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 299 ILADPEMRASL----RCIRCGACLNTCPVYqqlgghaygWV---YSGPIGS------VLDPN-------LLGLKEAGSLp 358
Cdd:COG0479  128 RLQSPEDREKAddlaECILCGACVAACPNV---------WAnpdFLGPAALaqayrfALDPRdeeteerLEALEDEEGV- 197

                         90       100       110
                 ....*....|....*....|....*....|...
gi 505049406 359 YASTLCGACGDVCPVRIPLPQMLVTLRGRAVEA 391
Cdd:COG0479  198 WRCTTCGNCTEVCPKGIPPTKAIAKLKREALKR 230
PRK09326 PRK09326
F420H2 dehydrogenase subunit F; Provisional
 311-373 1.86e-04

F420H2 dehydrogenase subunit F; Provisional


Pssm-ID: 181779 [Multi-domain]  Cd Length: 341  Bit Score: 43.67  E-value: 1.86e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406 311 CIRCGACLNTCPVyqqlgghayGWVYSGPIGSVLDPNLLGLKEAGSLPYASTLCGACGDVCPV 373
Cdd:PRK09326  14 CTACGACEAVCPI---------GAITVDKKAEIRDPNDLELYEKGAAPNVCEGCLTCSRICPV 67
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 310-373 2.25e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 39.33  E-value: 2.25e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505049406 310 RCIRCGACLNTCPVyqqlggHAYGWVYSGPIgsVLDPNL-LGlkeagslpyastlCGACGDVCPV 373
Cdd:COG1149   12 KCIGCGLCVEVCPE------GAIKLDDGGAP--VVDPDLcTG-------------CGACVGVCPT 55
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
311-372 2.95e-04

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 39.01  E-value: 2.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505049406  311 CIRCGACLNTCPVyQQLGGHAYGWVYSGPIgSVLDPNLLGL---KEAGSLPYASTLCGACGDVCP 372
Cdd:pfam13484   1 CGSCGKCIDACPT-GAIVGPEGVLDARRCI-SYLTIEKKGLipdELRCLLGNRCYGCDICQDVCP 63
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 308-379 4.58e-04

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 39.54  E-value: 4.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  308 SLRCIRCGACLNTCPVyqqlgghaygwvysgpigsvldpNLLGLKEAGslpYAS--------TLCGACGDVCPVRIPLPQ 379
Cdd:TIGR00402  33 SAVCTRCGECASACEN-----------------------NILQLGQQG---QPTvefdnaecDFCGKCAEACPTNAFHPR 86
Fer4_9 pfam13187
4Fe-4S dicluster domain;
310-372 5.89e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 37.92  E-value: 5.89e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505049406  310 RCIRCGACLNTCPVyqqlggHAYGWVYSGPIGSVLDPNllglkeagslpYASTLCGACGDVCP 372
Cdd:pfam13187   1 KCTGCGACVAACPA------GAIVPDLVGQTIRGDIAG-----------LACIGCGACVDACP 46
dhsB TIGR00384
succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase ...
 299-372 1.42e-03

succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase and fumarate reductase are reverse directions of the same enzymatic interconversion, succinate + FAD+ = fumarate + FADH2 (EC 1.3.11.1). In E. coli, the forward and reverse reactions are catalyzed by distinct complexes: fumarate reductase operates under anaerobic conditions and succinate dehydrogenase operates under aerobic conditions. This model also describes a region of the B subunit of a cytosolic archaeal fumarate reductase. [Energy metabolism, Aerobic, Energy metabolism, Anaerobic, Energy metabolism, TCA cycle]


Pssm-ID: 273049 [Multi-domain]  Cd Length: 220  Bit Score: 40.11  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406  299 ILADPEMRASLR----CIRCGACLNTCPvyqqlgghAYGWV--YSGPIGS------VLDP-------NLLGLKEAGSLpY 359
Cdd:TIGR00384 124 FLQTPEQREKLDqlsgCILCGCCYSSCP--------AFWWNpeFLGPAALtaayrfLIDSrdhatkdRLEGLNDKNGV-W 194

                          90
                  ....*....|...
gi 505049406  360 ASTLCGACGDVCP 372
Cdd:TIGR00384 195 RCTTCMNCSEVCP 207
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 310-372 2.13e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 38.78  E-value: 2.13e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505049406 310 RCIRCGACLNTCPvYQ--QLGGHAYGWvySGPIGSVLDPNLlglkeagslpYASTLCG-ACGDVCP 372
Cdd:cd16373   15 LCIRCGLCVEACP-TGviQPAGLEDGL--EGGRTPYLDPRE----------GPCDLCCdACVEVCP 67
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
292-323 3.37e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 36.25  E-value: 3.37e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 505049406 292 LDNGRSRIlaDPEmraslRCIRCGACLNTCPV 323
Cdd:COG2768   30 IEDGKAVI--DPE-----KCIGCGACIEVCPV 54
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 292-323 3.39e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.18  E-value: 3.39e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 505049406 292 LDNGRSRIlaDPEmraslRCIRCGACLNTCPV 323
Cdd:COG2221   34 LDDGKLVI--DEE-----KCIGCGACIRVCPT 58
glpC PRK11168
anaerobic glycerol-3-phosphate dehydrogenase subunit C;
311-474 4.25e-03

anaerobic glycerol-3-phosphate dehydrogenase subunit C;


Pssm-ID: 236869 [Multi-domain]  Cd Length: 396  Bit Score: 39.47  E-value: 4.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 311 CIRCGACLNTCPVyqqlgghaygwvysgpigSVLDPNLLGLKEAG----------------SLPYASTlCGACGDVCPVR 374
Cdd:PRK11168   9 CIKCTVCTTACPV------------------ARVNPLYPGPKQAGpdgerlrlkdgalydeSLKYCSN-CKRCEVACPSG 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505049406 375 IPLPQMLVTLRGRAVEagltSRGEALamRSFaqVMTRPRIY-RLASRGAR-------FSPWRggrlprlnlpllagWQLG 446
Cdd:PRK11168  70 VKIGDIIQRARAKYVT----ERGPPL--RDR--ILSHTDLMgSLATPFAPlvnaatgLKPVR--------------WLLE 127

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 505049406 447 --------RDFPAPARQGFRDLWASRLQYEQAEDGR 474
Cdd:PRK11168 128 ktlgidhrRPLPKYAFGTFRRWYRKQAAQQAQYKKQ 163
Fer4_4 pfam12800
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 310-324 6.69e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 463714  Cd Length: 17  Bit Score: 34.25  E-value: 6.69e-03
                          10
                  ....*....|....*
gi 505049406  310 RCIRCGACLNTCPVY 324
Cdd:pfam12800   3 KCIGCGACVDACPYG 17
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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