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Conserved domains on  [gi|515629725|ref|WP_017062325|]
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MULTISPECIES: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [Vibrio]

Protein Classification

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase( domain architecture ID 10013109)

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 1-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


:

Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 752.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKR 80
Cdd:PRK08849   1 MNKYDIAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  81 LETWEHPECRTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEF-GEINIVKLQSGAELSAKWVV 159
Cdd:PRK08849  81 LETWEHPECRTRFHSDELNLDQLGYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFsAEGNRVTLESGAEIEAKWVI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 160 GADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTsdgqevglGSLVWYDSPLRI 239
Cdd:PRK08849 161 GADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGNQ--------GSLVWYDSPKRI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 240 KQLSAMAPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV 319
Cdd:PRK08849 233 KQLSAMNPEQLRSEILRHFPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAE 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515629725 320 TKEKGELNQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08849 313 TEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALGM 384
 
Name Accession Description Interval E-value
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 1-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 752.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKR 80
Cdd:PRK08849   1 MNKYDIAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  81 LETWEHPECRTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEF-GEINIVKLQSGAELSAKWVV 159
Cdd:PRK08849  81 LETWEHPECRTRFHSDELNLDQLGYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFsAEGNRVTLESGAEIEAKWVI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 160 GADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTsdgqevglGSLVWYDSPLRI 239
Cdd:PRK08849 161 GADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGNQ--------GSLVWYDSPKRI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 240 KQLSAMAPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV 319
Cdd:PRK08849 233 KQLSAMNPEQLRSEILRHFPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAE 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515629725 320 TKEKGELNQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08849 313 TEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALGM 384
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 16-390 4.05e-125

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 366.14  E-value: 4.05e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   16 AATAIGFAKQGLSVAVIEGFAPQAFdESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWE--HPEcRTRF 93
Cdd:TIGR01988  12 LALALALARSGLKVALIEATPLPAP-ADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDggSFG-ALRF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   94 DAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFgEIN--IVKLQSGAELSAKWVVGADGANSAVRQQ 171
Cdd:TIGR01988  90 DADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPR-HSDhvELTLDDGQQLRARLLVGADGANSKVRQL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  172 AGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltSDgqevGLGSLVWYDSPLRIKQLSAMAPEKLR 251
Cdd:TIGR01988 169 AGIPTTGWDYGQSAVVANVKHERPHQGTAWERFTPTGPLALLPL----PD----NRSSLVWTLPPEEAERLLALSDEEFL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  252 NEVLTHFPKELGDIKVLNSGS-FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV---TKEKGELN 327
Cdd:TIGR01988 241 AELQRAFGSRLGAITLVGERHaFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVledARRRGEDI 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515629725  328 QSVA--RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:TIGR01988 321 GSLRvlQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 16-382 2.05e-61

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 200.93  E-value: 2.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEGFAPQAFDesqamdIRVSAISQASVDLLENLGAWQSIAAmRVCSYKRLETWEHP--ECRTRF 93
Cdd:COG0654   16 LALALALARAGIRVTVVERAPPPRPD------GRGIALSPRSLELLRRLGLWDRLLA-RGAPIRGIRVRDGSdgRVLARF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  94 DAASLDLPRlGYIVENRLIQLGLWSQFDAYdNLELLCPEKL-DVIEFGEINIVKLQSGAELSAKWVVGADGANSAVRQQA 172
Cdd:COG0654   89 DAAETGLPA-GLVVPRADLERALLEAARAL-GVELRFGTEVtGLEQDADGVTVTLADGRTLRADLVVGADGARSAVRRLL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 173 GIGITAWDYRQHCMLINVETEqpqqditwqqflpsgprsflplcsltsdgqevglgslvwydsplrikqlsamapekLRN 252
Cdd:COG0654  167 GIGFTGRDYPQRALWAGVRTE--------------------------------------------------------LRA 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 253 EVLTHFPkELGDIK-VLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV--TKEKGELNQS 329
Cdd:COG0654  191 RLAAAGP-RLGELLeLSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKlaAALRGRDDEA 269

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 515629725 330 VARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKA 382
Cdd:COG0654  270 ALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKG 322
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 16-316 1.50e-16

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 80.06  E-value: 1.50e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   16 AATAIGFAKQGLSVAVIEGFAPqAFDESQAmdirvSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEHPECRTRFDA 95
Cdd:pfam01494  14 LMLALLLARAGVRVVLVERHAT-TSVLPRA-----HGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRRRADLDF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   96 -----ASLDLP--RLGYIVENRLIQLGlwsqFDAYDNLELLCPEKLDVIEFGEINIVKLQSGAELSAKWVVGADGANSAV 168
Cdd:pfam01494  88 ltsppRVTVYPqtELEPILVEHAEARG----AQVRFGTEVLSLEQDGDGVTAVVRDRRDGEEYTVRAKYLVGCDGGRSPV 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  169 RQQAGIGITAWDY-RQHCMLINVETE---QPQQDITWQQFLPSGPRSFLPLCSLTSDGQEVGLGSLVWYD-----SPLRI 239
Cdd:pfam01494 164 RKTLGIEFEGFEGvPFGSLDVLFDAPdlsDPVERAFVHYLIYAPHSRGFMVGPWRSAGRERYYVQVPWDEeveerPEEFT 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515629725  240 kqlsamaPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVL 316
Cdd:pfam01494 244 -------DEELKQRLRSIVGIDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNL 313
 
Name Accession Description Interval E-value
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 1-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 752.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKR 80
Cdd:PRK08849   1 MNKYDIAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  81 LETWEHPECRTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEF-GEINIVKLQSGAELSAKWVV 159
Cdd:PRK08849  81 LETWEHPECRTRFHSDELNLDQLGYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFsAEGNRVTLESGAEIEAKWVI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 160 GADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTsdgqevglGSLVWYDSPLRI 239
Cdd:PRK08849 161 GADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGNQ--------GSLVWYDSPKRI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 240 KQLSAMAPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV 319
Cdd:PRK08849 233 KQLSAMNPEQLRSEILRHFPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAE 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515629725 320 TKEKGELNQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08849 313 TEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALGM 384
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 4-391 0e+00

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 527.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   4 YDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLET 83
Cdd:PRK08020   6 TDIAIVGGGMVGAALALGLAQHGFSVAVLEHAAPAPFDADSQPDVRISAISAASVALLKGLGVWDAVQAMRSHPYRRLET 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  84 WEHPECRTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEIN-IVKLQSGAELSAKWVVGAD 162
Cdd:PRK08020  86 WEWETAHVVFDAAELKLPELGYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGwELTLADGEEIQAKLVIGAD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 163 GANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSltsdgqevGLGSLVWYDSPLRIKQL 242
Cdd:PRK08020 166 GANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFD--------NWASLVWYDSPARIRQL 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 243 SAMAPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV--- 319
Cdd:PRK08020 238 QAMSMAQLQQEIAAHFPARLGAVTPVAAGAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVlvn 317

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515629725 320 TKEKGEL--NQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08020 318 ARSYGEAwaSEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYALGL 391
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 16-390 4.05e-125

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 366.14  E-value: 4.05e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   16 AATAIGFAKQGLSVAVIEGFAPQAFdESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWE--HPEcRTRF 93
Cdd:TIGR01988  12 LALALALARSGLKVALIEATPLPAP-ADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDggSFG-ALRF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   94 DAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFgEIN--IVKLQSGAELSAKWVVGADGANSAVRQQ 171
Cdd:TIGR01988  90 DADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPR-HSDhvELTLDDGQQLRARLLVGADGANSKVRQL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  172 AGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltSDgqevGLGSLVWYDSPLRIKQLSAMAPEKLR 251
Cdd:TIGR01988 169 AGIPTTGWDYGQSAVVANVKHERPHQGTAWERFTPTGPLALLPL----PD----NRSSLVWTLPPEEAERLLALSDEEFL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  252 NEVLTHFPKELGDIKVLNSGS-FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV---TKEKGELN 327
Cdd:TIGR01988 241 AELQRAFGSRLGAITLVGERHaFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVledARRRGEDI 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515629725  328 QSVA--RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:TIGR01988 321 GSLRvlQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 1-391 1.13e-93

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 286.67  E-value: 1.13e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAfDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKR 80
Cdd:PRK08850   2 MQSVDVAIIGGGMVGLALAAALKESDLRIAVIEGQLPEE-ALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  81 LETWEHPE-CRTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEINI-VKLQSGAELSAKWV 158
Cdd:PRK08850  81 MEVWEQDSfARIEFDAESMAQPDLGHIVENRVIQLALLEQVQKQDNVTLLMPARCQSIAVGESEAwLTLDNGQALTAKLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 159 VGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltsdgQEVGLGSLVWYDSPLR 238
Cdd:PRK08850 161 VGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDPHNSVARQIFTPQGPLAFLPM-------SEPNMSSIVWSTEPLR 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 239 IKQLSAMAPEKLRNEVLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLL 317
Cdd:PRK08850 234 AEALLAMSDEQFNKALTAEFDNRLGLCEVVGErQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLA 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515629725 318 DVTKEKGELNQSVA-----RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08850 314 QEILALWQQGRDIGlkrnlRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRALGL 392
PRK08013 PRK08013
oxidoreductase; Provisional
 1-391 3.72e-93

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 285.02  E-value: 3.72e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKR 80
Cdd:PRK08013   1 MQSVDVVIAGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  81 LETWEHPEC-RTRFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEIN-IVKLQSGAELSAKWV 158
Cdd:PRK08013  81 MEVWDKDSFgRIAFDDQSMGYSHLGHIIENSVIHYALWQKAQQSSDITLLAPAELQQVAWGENEaFLTLKDGSMLTARLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 159 VGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltsdgQEVGLGSLVWYDSPLR 238
Cdd:PRK08013 161 VGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGDGILAFLPL-------SDPHLCSIVWSLSPEE 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 239 IKQLSAMAPEKLRNEVLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLL 317
Cdd:PRK08013 234 AQRMQQAPEEEFNRALAIAFDNRLGLCELESErQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELI 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515629725 318 D----VTKEKGELNQSV-ARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK08013 314 AelrrLHRQGKDIGQHLyLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL 392
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
16-390 2.95e-81

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 254.11  E-value: 2.95e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEGFAPQAfDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEHPECRTRFDA 95
Cdd:PRK07608  18 ASLALALAQSGLRVALLAPRAPPR-PADDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFGDAHARLHFSA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  96 ASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLcPEKLDVIEFGEINI-VKLQSGAELSAKWVVGADGANSAVRQQAGI 174
Cdd:PRK07608  97 YQAGVPQLAWIVESSLIERALWAALRFQPNLTWF-PARAQGLEVDPDAAtLTLADGQVLRADLVVGADGAHSWVRSQAGI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 175 GITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltsDGQEVglgSLVWYDSPLRIKQLSAMAPEKLRNEV 254
Cdd:PRK07608 176 KAERRPYRQTGVVANFKAERPHRGTAYQWFRDDGILALLPL-----PDGHV---SMVWSARTAHADELLALSPEALAARV 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 255 LTHFPKELGDIKVLNSG-SFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGELNQ----S 329
Cdd:PRK07608 248 ERASGGRLGRLECVTPAaGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGREPFRDlgdlR 327

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515629725 330 VARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:PRK07608 328 LLRRYERARREDILALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 16-391 4.38e-78

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 246.28  E-value: 4.38e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEG--FAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEHPEC-RTR 92
Cdd:PRK05714  15 SALALALQGSGLEVLLLDGgpLSVKPFDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSGTgQIH 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  93 FDAASLDLPRLGYIVENRLIQLGLWSQFDAYDnLELLCPEKLDVIE-FGEINIVKLQSGAELSAKWVVGADGANSAVRQQ 171
Cdd:PRK05714  95 FSAASVHAEVLGHIVENRVVQDALLERLHDSD-IGLLANARLEQMRrSGDDWLLTLADGRQLRAPLVVAADGANSAVRRL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 172 AGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPlcsLTSDGQEvGLGSLVWYDSPLRIKQLSAMAPEKLR 251
Cdd:PRK05714 174 AGCATREWDYLHHAIVTSVRCSEPHRATAWQRFTDDGPLAFLP---LERDGDE-HWCSIVWSTTPEEAERLMALDDDAFC 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 252 NEVLTHFPKELGdiKVLNSGS---FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV---TKEKGE 325
Cdd:PRK05714 250 AALERAFEGRLG--EVLSADPrlcVPLRQRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVllhAAERGE 327

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515629725 326 --LNQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK05714 328 rlADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKLVDQMPEAKALFVRQALGL 395
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
16-390 1.95e-72

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 231.29  E-value: 1.95e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEGFAPQAFDESQAmDIRVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEHPEC-RTRFD 94
Cdd:PRK08773  19 AACALALADAGLSVALVEGREPPRWQADQP-DLRVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDAGGGgELGFD 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  95 AASLDLPRLGYIVENRLIQLGLWSQFDAyDNLELLCPEKLDVIEFGEINI-VKLQSGAELSAKWVVGADGANSAVRQQAG 173
Cdd:PRK08773  98 ADTLGREQLGWIVENDLLVDRLWAALHA-AGVQLHCPARVVALEQDADRVrLRLDDGRRLEAALAIAADGAASTLRELAG 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 174 IGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltSDGQEvglgSLVWYDSPLRIKQLSAMAPEKLRNE 253
Cdd:PRK08773 177 LPVSRHDYAQRGVVAFVDTEHPHQATAWQRFLPTGPLALLPF----ADGRS----SIVWTLPDAEAERVLALDEAAFSRE 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 254 VLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGELNQSVA- 331
Cdd:PRK08773 249 LTQAFAARLGEVRVASPrTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAa 328

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515629725 332 ----RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:PRK08773 329 phrlQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPLVDALWKRASG 391
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 16-390 9.15e-70

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 224.11  E-value: 9.15e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   16 AATAIGFAKQG-LSVAVIEGFAPQAFDESQamDIRVSAISQASVDLLENLGAWQSIAAmRVCSYKRLETWE--HPEcRTR 92
Cdd:TIGR01984  12 LSLALALSRLGkIKIALIEANSPSAAQPGF--DARSLALSYGSKQILEKLGLWPKLAP-FATPILDIHVSDqgHFG-ATH 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   93 FDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEI-NIVKLQSGAELSAKWVVGADGANSAVRQQ 171
Cdd:TIGR01984  88 LRASEFGLPALGYVVELADLGQALLSRLALLTNIQLYCPARYKEIIRNQDyVRVTLDNGQQLRAKLLIAADGANSKVREL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  172 AGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltsdgQEVGLGSLVWYDSPLRIKQLSAMAPEKLR 251
Cdd:TIGR01984 168 LSIPTEEHDYNQTALIANIRHEQPHQGCAFERFTPHGPLALLPL-------KDNYRSSLVWCLPSKQADTIANLPDAEFL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  252 NEVLTHFPKELGDIKVLNSGS-FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV--TKEKGELNQ 328
Cdd:TIGR01984 241 AELQQAFGWRLGKITQVGERKtYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVliDARIDLGTY 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515629725  329 SVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:TIGR01984 321 ALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 49-385 6.72e-67

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 218.47  E-value: 6.72e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   49 RVSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEH-PECRTRFDAASLDLPrLGYIVENRLIQLGLWSQFDAY--DN 125
Cdd:TIGR01989  56 RVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDGcSLALIRFDRDNGKED-MACIIENDNIQNSLYNRLQEYngDN 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  126 LELLCPEKLDVIEFGE------INIVKLQ--SGAELSAKWVVGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQ-PQ 196
Cdd:TIGR01989 135 VKILNPARLISVTIPSkypndnSNWVHITlsDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEaTE 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  197 QDITWQQFLPSGPRSFLPLcsltSDgqevGLGSLVWYDSPLRIKQLSAMAPEKLRNEV----------LTHFPKELGDIK 266
Cdd:TIGR01989 215 NDVAWQRFLPTGPIALLPL----PD----NNSTLVWSTSPEEALRLLSLPPEDFVDALnaafdlgysdHPYSYLLDYAME 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  267 VLNS---------------------------GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV 319
Cdd:TIGR01989 287 KLNEdigfrtegskscfqvpprvigvvdksrAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKA 366

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515629725  320 TKEKGELNQSVA-----RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVL 385
Cdd:TIGR01989 367 LAEAVSVGADIGsisslKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 16-382 2.05e-61

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 200.93  E-value: 2.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEGFAPQAFDesqamdIRVSAISQASVDLLENLGAWQSIAAmRVCSYKRLETWEHP--ECRTRF 93
Cdd:COG0654   16 LALALALARAGIRVTVVERAPPPRPD------GRGIALSPRSLELLRRLGLWDRLLA-RGAPIRGIRVRDGSdgRVLARF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  94 DAASLDLPRlGYIVENRLIQLGLWSQFDAYdNLELLCPEKL-DVIEFGEINIVKLQSGAELSAKWVVGADGANSAVRQQA 172
Cdd:COG0654   89 DAAETGLPA-GLVVPRADLERALLEAARAL-GVELRFGTEVtGLEQDADGVTVTLADGRTLRADLVVGADGARSAVRRLL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 173 GIGITAWDYRQHCMLINVETEqpqqditwqqflpsgprsflplcsltsdgqevglgslvwydsplrikqlsamapekLRN 252
Cdd:COG0654  167 GIGFTGRDYPQRALWAGVRTE--------------------------------------------------------LRA 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 253 EVLTHFPkELGDIK-VLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV--TKEKGELNQS 329
Cdd:COG0654  191 RLAAAGP-RLGELLeLSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKlaAALRGRDDEA 269

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 515629725 330 VARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKA 382
Cdd:COG0654  270 ALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKG 322
PRK07364 PRK07364
FAD-dependent hydroxylase;
19-391 2.81e-61

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 202.94  E-value: 2.81e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  19 AIGFAKQGLSVAVIEG-FAPQAFDESQAMdirvsAISQASVDLLENLGAWQSIAAmRVCSYK--RLETWEHPEcRTRFDA 95
Cdd:PRK07364  34 AAALKDSGLRIALIEAqPAEAAAAKGQAY-----ALSLLSARIFEGIGVWEKILP-QIGKFRqiRLSDADYPG-VVKFQP 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  96 ASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGE----INIVKLQSGAELSAKWVVGADGANSAVRQQ 171
Cdd:PRK07364 107 TDLGTEALGYVGEHQVLLEALQEFLQSCPNITWLCPAEVVSVEYQQdaatVTLEIEGKQQTLQSKLVVAADGARSPIRQA 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 172 AGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPL----CsltsdgqevglgSLVWYDSPLRIKQLSAMAP 247
Cdd:PRK07364 187 AGIKTKGWKYWQSCVTATVKHEAPHNDIAYERFWPSGPFAILPLpgnrC------------QIVWTAPHAQAKALLALPE 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 248 EKLRNEVLTHFPKELGDIKVLNSGS-FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKE---K 323
Cdd:PRK07364 255 AEFLAELQQRYGDQLGKLELLGDRFlFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTahqR 334

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 324 GEL--NQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK07364 335 GEDigSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLALRLMTGL 404
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
16-391 2.00e-52

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 179.40  E-value: 2.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEGfapqAFDESQAMDIRVSAISQASVDLLENLGAWQSIA-------AMRVcsykrleTWEHPE 88
Cdd:PRK07333  16 LAVALKQAAPHLPVTVVDA----APAGAWSRDPRASAIAAAARRMLEALGVWDEIApeaqpitDMVI-------TDSRTS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  89 CRTR-----FDAASLDLPRLGYIVENRLIQLGLWSQFDAYDnLELLcpEKLDVIEF---GEINIVKLQSGAELSAKWVVG 160
Cdd:PRK07333  85 DPVRpvfltFEGEVEPGEPFAHMVENRVLINALRKRAEALG-IDLR--EATSVTDFetrDEGVTVTLSDGSVLEARLLVA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 161 ADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTSdgqevglgSLVWYDSPLRIK 240
Cdd:PRK07333 162 ADGARSKLRELAGIKTVGWDYGQSGIVCTVEHERPHGGRAEEHFLPAGPFAILPLKGNRS--------SLVWTERTADAE 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 241 QLSAMAPEKLRNEVLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDV 319
Cdd:PRK07333 234 RLVALDDLVFEAELEQRFGHRLGELKVLGKrRAFPLGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEV 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515629725 320 TKEKGELNQ-----SVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK07333 314 VVEAARLGLdigslDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFFIRQAAGL 390
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 23-391 7.14e-51

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 175.04  E-value: 7.14e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  23 AKQGLSVAVIEGFAPQAfDESQAMDIRVSAISQASVDLLENLGAWQSIAaMRVCSYKRLETWEHPEC-RTRFDAASLDLP 101
Cdd:PRK05732  26 SHGGLPVALIEAFAPES-DAHPGFDARAIALAAGTCQQLARLGVWQALA-DCATPITHIHVSDRGHAgFVRLDAEDYGVP 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 102 RLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEIN-IVKLQSGAELSAKWVVGADGANSAVRQQAGIGITAWD 180
Cdd:PRK05732 104 ALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSvRVTLDDGETLTGRLLVAADGSHSALREALGIDWQQHP 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 181 YRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltSDGQEvglgSLVWYDSPLRIKQLSAMAPEKLRNEVLTHFPK 260
Cdd:PRK05732 184 YEQVAVIANVTTSEAHQGRAFERFTEHGPLALLPM----SDGRC----SLVWCHPLEDAEEVLSWSDAQFLAELQQAFGW 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 261 ELGdiKVLNSG---SFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGELNQ-----SVAR 332
Cdd:PRK05732 256 RLG--RITHAGkrsAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEdigdyAVLQ 333

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515629725 333 RYEVMRRGD--NLVMQSgmDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALGL 391
Cdd:PRK05732 334 RYQQRRQQDreATIGFT--DGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLGW 392
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
1-382 2.22e-48

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 168.54  E-value: 2.22e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   1 MNSYDIVVVGGGMVGAATAIGFAKQGLSVAVIEGFAPQAfdesqamDIRVSAISQASVDLLENLGAWQSIA-------AM 73
Cdd:PRK07494   5 KEHTDIAVIGGGPAGLAAAIALARAGASVALVAPEPPYA-------DLRTTALLGPSIRFLERLGLWARLAphaaplqSM 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  74 R-VCSYKRLetwehPECRT-RFDAASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKLDVIEFGEINIVKLQSGA 151
Cdd:PRK07494  78 RiVDATGRL-----IRAPEvRFRAAEIGEDAFGYNIPNWLLNRALEARVAELPNITRFGDEAESVRPREDEVTVTLADGT 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 152 ELSAKWVVGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTSdgqevglgSLV 231
Cdd:PRK07494 153 TLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQNVSTEFHTEGGPFTQVPLPGRRS--------SLV 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 232 WYDSPLRIKQLSAMAPEKLRNEVLTHFPKELGDIKVlNSG--SFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLG 309
Cdd:PRK07494 225 WVVRPAEAERLLALSDAALSAAIEERMQSMLGKLTL-EPGrqAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLG 303

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515629725 310 FKDVSVLLDVTKEKGE--LNQSVARRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKA 382
Cdd:PRK07494 304 LRDVATLVEIVEDRPEdpGSAAVLAAYDRARRPDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRR 378
PRK09126 PRK09126
FAD-dependent hydroxylase;
17-387 8.03e-39

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 143.16  E-value: 8.03e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  17 ATAIGFAKQGLSVAVIEGfAPQAFDESQAMDIRVSAISQASVDLLENLGAWQSIAAMRVCSYK--RLETWEHPECRTrFD 94
Cdd:PRK09126  17 SFARSLAGSGLKVTLIER-QPLAALADPAFDGREIALTHASREILQRLGAWDRIPEDEISPLRdaKVLNGRSPFALT-FD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  95 AASLDLPRLGYIVENRLIQLGLWSQFDAYDNLELLCPEKL-DVIEFGEINIVKLQSGAELSAKWVVGADGANSAVRQQAG 173
Cdd:PRK09126  95 ARGRGADALGYLVPNHLIRRAAYEAVSQQDGIELLTGTRVtAVRTDDDGAQVTLANGRRLTARLLVAADSRFSATRRQLG 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 174 IGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTSdgqevglgSLVWYDSPLRIKQLSAMAPEKLRNE 253
Cdd:PRK09126 175 IGADMHDFGRTMLVCRMRHELPHHHTAWEWFGYGQTLALLPLNGHLS--------SLVLTLPPDQIEALLALDPEAFAAE 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 254 VLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGELNQSVA- 331
Cdd:PRK09126 247 VTARFKGRLGAMRLVSSrHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGa 326

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 332 ----RRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKY 387
Cdd:PRK09126 327 asllERYERKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQAIAKQ 386
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 18-390 6.73e-37

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 137.75  E-value: 6.73e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  18 TAIGFAKQGLSVAVIEGF---APQAFDesqamDIRVSAISQASVDLLENLGAWQS----IAAMR---VCSYKRLETWEhp 87
Cdd:PRK06617  16 TALSFAQKGIKTTIFESKsvkSPEFFK-----DIRTTALTPHSKNFLFSIDIWEElekfVAEMQdiyVVDNKASEILD-- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  88 ecrTRFDAASLdlprLGYIVENRLIQLGLWSQFDAYDNLELLCPEKL-DVIEFGEINIVKLQSgAELSAKWVVGADGANS 166
Cdd:PRK06617  89 ---LRNDADAV----LGYVVKNSDFKKILLSKITNNPLITLIDNNQYqEVISHNDYSIIKFDD-KQIKCNLLIICDGANS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 167 AVRQQAGIGITAWDYrQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLCSLTSDgqevglgSLVWYDSPLRIKQLSAMA 246
Cdd:PRK06617 161 KVRSHYFANEIEKPY-QTALTFNIKHEKPHENCAMEHFLPLGPFALLPLKDQYAS-------SVIWSTSSDQAALIVNLP 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 247 PEKLRNEVLTHFPKELGDIKVLNS-GSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGE 325
Cdd:PRK06617 233 VEEVRFLTQRNAGNSLGKITIDSEiSSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSNNGT 312

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515629725 326 LnqsvaRRYEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKAQVLKYALG 390
Cdd:PRK06617 313 L-----QEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYAMG 372
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
23-382 4.87e-28

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 113.63  E-value: 4.87e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  23 AKQGLSVAVIEGFAPqafdESQAMDIRVSAISQASVDLLENLGAW----QSIAAMRVCSYKRLEtwehpecRTRFDAASL 98
Cdd:PRK06996  35 ATRALSIALIDAREP----AASANDPRAIALSHGSRVLLETLGAWpadaTPIEHIHVSQRGHFG-------RTLIDRDDH 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  99 DLPRLGYIVENRLIQLGLWSQFDAY-DNLELLCPEKLDVIEFG--EINIVKLQSGAELSAKWVVGADGA-NSAVRQQAGI 174
Cdd:PRK06996 104 DVPALGYVVRYGSLVAALARAVRGTpVRWLTSTTAHAPAQDADgvTLALGTPQGARTLRARIAVQAEGGlFHDQKADAGD 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 175 GITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltsDGQEVGLGSLVWYDSPLRIKQLSAMAPEKLRNEV 254
Cdd:PRK06996 184 SARRRDYGQTAIVGTVTVSAPRPGWAWERFTHEGPLALLPL-----GGPRQADYALVWCCAPDEAARRAALPDDAFLAEL 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 255 LTHFPKELGDI-KVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLDVTKEKGELNQSVArR 333
Cdd:PRK06996 259 GAAFGTRMGRFtRIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDHGATPLALA-T 337

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 515629725 334 YEVMRRGDNLVMQSGMDFFYKTFSNDIGPLKFVRNAALKLAENSGPIKA 382
Cdd:PRK06996 338 FAARRALDRRVTIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKH 386
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 16-316 1.50e-16

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 80.06  E-value: 1.50e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   16 AATAIGFAKQGLSVAVIEGFAPqAFDESQAmdirvSAISQASVDLLENLGAWQSIAAMRVCSYKRLETWEHPECRTRFDA 95
Cdd:pfam01494  14 LMLALLLARAGVRVVLVERHAT-TSVLPRA-----HGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRRRADLDF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   96 -----ASLDLP--RLGYIVENRLIQLGlwsqFDAYDNLELLCPEKLDVIEFGEINIVKLQSGAELSAKWVVGADGANSAV 168
Cdd:pfam01494  88 ltsppRVTVYPqtELEPILVEHAEARG----AQVRFGTEVLSLEQDGDGVTAVVRDRRDGEEYTVRAKYLVGCDGGRSPV 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  169 RQQAGIGITAWDY-RQHCMLINVETE---QPQQDITWQQFLPSGPRSFLPLCSLTSDGQEVGLGSLVWYD-----SPLRI 239
Cdd:pfam01494 164 RKTLGIEFEGFEGvPFGSLDVLFDAPdlsDPVERAFVHYLIYAPHSRGFMVGPWRSAGRERYYVQVPWDEeveerPEEFT 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515629725  240 kqlsamaPEKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVL 316
Cdd:pfam01494 244 -------DEELKQRLRSIVGIDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNL 313
PRK06834 PRK06834
hypothetical protein; Provisional
 145-312 4.53e-13

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 70.43  E-value: 4.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 145 VKLQSGAELSAKWVVGADGANSAVRQQAGIGITAWDYRQHCMLINVE-TEQPqqditwqqflPSGPRSflplcsltsdgQ 223
Cdd:PRK06834 135 VELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEmTEEP----------EWGVHR-----------D 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 224 EVGLGSL--VWYDSPLRI----KQLSAMA---PEKLRNEVLTHFPKELGdIKVLNSGS-FPLTRRHAQSYSKNNCILVGD 293
Cdd:PRK06834 194 ALGIHAFgrLEDEGPVRVmvteKQVGATGeptLDDLREALIAVYGTDYG-IHSPTWISrFTDMARQAASYRDGRVLLAGD 272

                        170
                 ....*....|....*....
gi 515629725 294 SAHTINPLAGQGVNLGFKD 312
Cdd:PRK06834 273 AAHVHSPVGGQGLNTGVQD 291
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
16-311 1.16e-11

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 64.60  E-value: 1.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  16 AATAIGFAKQGLSVAVIEgfaPQAFDESQamdIRVSAISQASVDLLENLGAWQSIAAmRVcsyKRLETWEHPECRTRFDA 95
Cdd:COG0644    6 SAAARRLARAGLSVLLLE---KGSFPGDK---ICGGGLLPRALEELEPLGLDEPLER-PV---RGARFYSPGGKSVELPP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  96 AsldlPRLGYIVeNRliqlglwSQFDAY-------DNLELLCPEKLDVIEF--GEInIVKLQSGAELSAKWVVGADGANS 166
Cdd:COG0644   76 G----RGGGYVV-DR-------ARFDRWlaeqaeeAGAEVRTGTRVTDVLRddGRV-VVRTGDGEEIRADYVVDADGARS 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 167 AVRQQAGIGITAWDYRQHCMLINVETEqpqqditwqqfLPSGPRSFLPLCSLTSDGQEVGLGSlvWYdsplrikqlsama 246
Cdd:COG0644  143 LLARKLGLKRRSDEPQDYALAIKEHWE-----------LPPLEGVDPGAVEFFFGEGAPGGYG--WV------------- 196

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515629725 247 peklrnevlthFPKELGDIKVlnsgSFPLtRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFK 311
Cdd:COG0644  197 -----------FPLGDGRVSV----GIPL-GGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMK 245
PRK06184 PRK06184
hypothetical protein; Provisional
 19-312 3.89e-11

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 64.23  E-value: 3.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  19 AIGFAKQGLSVAVIEGfAPQAFDESqamdiRVSAISQASVDLLENLGAWQSIAA-----MRVCSYK---RLETWEHPECR 90
Cdd:PRK06184  19 AIELARRGVSFRLIEK-APEPFPGS-----RGKGIQPRTQEVFDDLGVLDRVVAagglyPPMRIYRddgSVAESDMFAHL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  91 TRFDAASLDLP------RLGYIVENRLIQLGLWSQFDAydnlELL----CPEKLDViefgeiNIVKLQSGAELSAKWVVG 160
Cdd:PRK06184  93 EPTPDEPYPLPlmvpqwRTERILRERLAELGHRVEFGC----ELVgfeqDADGVTA------RVAGPAGEETVRARYLVG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 161 ADGANSAVRQQAGIGITAWDYRQHCMLI-NVETEQPQQDiTWQQFlPSGPRSFLPLCSL--TSDGQ---EVGLGSLVwyd 234
Cdd:PRK06184 163 ADGGRSFVRKALGIGFPGETLGIDRMLVaDVSLTGLDRD-AWHQW-PDGDMGMIALCPLpgTDLFQiqaPLPPGGEP--- 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515629725 235 sPLRIKQLSAMAPEKL-RNEVLTHFPKELGDikvlnsgsFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKD 312
Cdd:PRK06184 238 -DLSADGLTALLAERTgRTDIRLHSVTWASA--------FRMNARLADRYRVGRVFLAGDAAHVHPPAGGQGLNTSVQD 307
PRK08244 PRK08244
monooxygenase;
153-312 4.00e-11

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 64.38  E-value: 4.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 153 LSAKWVVGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQPQQDITWQQFLPSGPRSFLPLcsltSDGQevglgSLVW 232
Cdd:PRK08244 146 LTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVLSLCTREGGVMIVPL----SGGI-----YRVL 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 233 YDSPLRIkQLSAMAP---EKLRNEVLTHFPKELGDIKVLNSGSFPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLG 309
Cdd:PRK08244 217 IIDPERP-QVPKDEPvtlEELKTSLIRICGTDFGLNDPVWMSRFGNATRQAERYRSGRIFLAGDAAHIHFPAGGQGLNVG 295


                 ...
gi 515629725 310 FKD 312
Cdd:PRK08244 296 LQD 298
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
151-316 3.08e-09

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 58.38  E-value: 3.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 151 AELSAKWVVGADGANSAVRQQAGIGITAWDYRQHCMLINVETEQP--QQDITWQQFLPSGPRSFLPLcsltsdgqevGLG 228
Cdd:PRK06183 159 ETVRARYVVGCDGANSFVRRTLGVPFEDLTFPERWLVVDVLIANDplGGPHTYQYCDPARPYTSVRL----------PHG 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 229 SLVW------------YDSPLRIKQLSA---MAPEKL---RNEVLTHfpkelgdikvlNSgsfpltrRHAQSYSKNNCIL 290
Cdd:PRK06183 229 RRRWefmllpgeteeqLASPENVWRLLApwgPTPDDAeliRHAVYTF-----------HA-------RVADRWRSGRVLL 290

                        170       180
                 ....*....|....*....|....*.
gi 515629725 291 VGDSAHTINPLAGQGVNLGFKDVSVL 316
Cdd:PRK06183 291 AGDAAHLMPPFAGQGMNSGIRDAANL 316
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 4-309 8.87e-08

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 53.09  E-value: 8.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725    4 YDIVVVGGGMVGAATAIGFAKQGLSVAVIEgfapqafdesQAMDIRV----SAISQASVDLLENLGAwqSIAAMRVCSYK 79
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLE----------KKSFPRYkpcgGALSPRALEELDLPGE--LIVNLVRGARF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725   80 RletweHPECRtrfdaaSLDLPR---LGYIVeNRliqlglwsqfDAYDNL----------ELLCPEKL--DVIEFGEINI 144
Cdd:TIGR02032  69 F-----SPNGD------SVEIPIeteLAYVI-DR----------DAFDEQlaeraqeagaELRLGTRVldVEIHDDRVVV 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  145 VKLQSGAELSAKWVVGADGANSAVRQQAGigitAW-DYRQhcMLINVETEQPQQDITWQQ-----FLPSG--PRSFLPLC 216
Cdd:TIGR02032 127 IVRGSEGTVTAKIVIGADGSRSIVAKKLG----LKkEPRE--YGVAARAEVEMPDEEVDEdfvevYIDRGivPGGYGWVF 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725  217 SLTSDGQEVGLGSlvwydsplrikqLSAMAPEKLRnEVLTHFPK---ELGDIKVLNSGSFPL-TRRHAQSYSKNNCILVG 292
Cdd:TIGR02032 201 PKGDGTANVGVGS------------RSAEEGEDPK-KYLKDFLArrpELKDAETVEVCGALIpIGRPDEKLVRGNVLLVG 267

                         330
                  ....*....|....*..
gi 515629725  293 DSAHTINPLAGQGVNLG 309
Cdd:TIGR02032 268 DAAGHVNPLTGEGIYYA 284
PRK07045 PRK07045
putative monooxygenase; Reviewed
 116-318 2.60e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 52.22  E-value: 2.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 116 LWSQFDAYDNLELLCPEKLDVIEF---GEINIVKLQSGAELSAKWVVGADGANSAVRQQA--------------GIGITA 178
Cdd:PRK07045 112 LLAKLDGLPNVRLRFETSIERIERdadGTVTSVTLSDGERVAPTVLVGADGARSMIRDDVlrmpaervpyatpmAFGTIA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 179 W-DYRQHCMLINVETeqpQQDITWqqFLPSGPRSFLPLCSLTSDGQEvglgslvwydsplriKQLSAMAPEKLRNEVLTH 257
Cdd:PRK07045 192 LtDSVRECNRLYVDS---NQGLAY--FYPIGDQATRLVVSFPADEMQ---------------GYLADTTRTKLLARLNEF 251

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515629725 258 FPKELGD-IKVLNSGS----FPLTRRHAQSYSKNNCILVGDSAHTINPLAGQGVNLGFKDVSVLLD 318
Cdd:PRK07045 252 VGDESADaMAAIGAGTafplIPLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGA 317
PRK06126 PRK06126
hypothetical protein; Provisional
 143-339 5.64e-07

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 51.53  E-value: 5.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 143 NIVKLQSGAELS--AKWVVGADGANSAVRQQAGI---GITAWDYRQhcmliNVETEQPQ------QDITWQQFLpSGPRS 211
Cdd:PRK06126 163 TVEDLDGGESLTirADYLVGCDGARSAVRRSLGIsyeGTSGLQRDL-----SIYIRAPGlaalvgHDPAWMYWL-FNPDR 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 212 FLPLCSLtsDGQEVglgslvWydsplRIKQLSAMAPEKLRNEVLTH--FPKELG---DIKVLNSGSFPLTRRHAQSYSKN 286
Cdd:PRK06126 237 RGVLVAI--DGRDE------W-----LFHQLRGGEDEFTIDDVDARafVRRGVGediDYEVLSVVPWTGRRLVADSYRRG 303

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515629725 287 NCILVGDSAHTINPLAGQG--------VNLGFKDVSVLldvtkeKGELNQSVARRYEVMRR 339
Cdd:PRK06126 304 RVFLAGDAAHLFTPTGGYGmntgigdaVNLAWKLAAVL------NGWAGPALLDSYEAERR 358
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 152-316 2.13e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 43.30  E-value: 2.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 152 ELSAKWVVGADGANSAVRQQAGIGITAWDYRQH---CMLINVETEQPQQDITWqqFLPSGPrsflpLCSLTSDGQEVGLg 228
Cdd:PTZ00367 205 VATAPLVVMCDGGMSKFKSRYQHYTPASENHSHfvgLVLKNVRLPKEQHGTVF--LGKTGP-----ILSYRLDDNELRV- 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515629725 229 sLVWYDSPLrIKQLSAMApEKLRNEVLTHFPKELGD--IKVLNSG----SFPLTRRHAQSYSKNNCILVGDSAHTINPLA 302
Cdd:PTZ00367 277 -LVDYNKPT-LPSLEEQS-EWLIEDVAPHLPENMREsfIRASKDTkrirSMPNARYPPAFPSIKGYVGIGDHANQRHPLT 353

                        170
                 ....*....|....
gi 515629725 303 GQGVNLGFKDVSVL 316
Cdd:PTZ00367 354 GGGMTCCFSDCIRL 367
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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