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Conserved domains on  [gi|515952498|ref|WP_017383081|]
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MULTISPECIES: putrescine export ABC transporter permease SapB [Enterobacter]

Protein Classification

peptide ABC transporter permease SapB( domain architecture ID 10794134)

peptide ABC transporter permease SapB is part of a putrescine export transport system; does not play a role in resistance to antimicrobial peptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15110 PRK15110
peptide ABC transporter permease SapB;
23-321 0e+00

peptide ABC transporter permease SapB;


:

Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 551.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  23 GFSLSYFTPHAPLQGSSLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIY 102
Cdd:PRK15110  23 GFSLSYFTPHAPLQGASLWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 103 RNKWQDKFISALALIGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYNVQTVSGFAIVDAWLSDSVWRDEMIVSALRH 182
Cdd:PRK15110 103 RHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFALIDAWLSDSPWRDEMIMSAIRH 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 183 MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262
Cdd:PRK15110 183 MILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515952498 263 FSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANPLKHKEWYALR 321
Cdd:PRK15110 263 FSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKHKEWYALR 321
 
Name Accession Description Interval E-value
PRK15110 PRK15110
peptide ABC transporter permease SapB;
23-321 0e+00

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 551.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  23 GFSLSYFTPHAPLQGSSLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIY 102
Cdd:PRK15110  23 GFSLSYFTPHAPLQGASLWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 103 RNKWQDKFISALALIGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYNVQTVSGFAIVDAWLSDSVWRDEMIVSALRH 182
Cdd:PRK15110 103 RHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFALIDAWLSDSPWRDEMIMSAIRH 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 183 MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262
Cdd:PRK15110 183 MILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515952498 263 FSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANPLKHKEWYALR 321
Cdd:PRK15110 263 FSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKHKEWYALR 321
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
23-321 6.72e-175

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 487.04  E-value: 6.72e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  23 GFSLSYFTPHAPLQGSSLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIY 102
Cdd:COG4168   23 SFSLLYRDPLNPLSDASLFSGYLFYLQNLLQGDFGISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIY 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 103 RNKWQDKFISALALIGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYNVQTVSGFAIVDAWLSDSVWRDEMIVSALRH 182
Cdd:COG4168  103 RGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYEIPPVTGFALIDAWLSDSPYRLKAIQSALQH 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 183 MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262
Cdd:COG4168  183 LILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVV 262

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515952498 263 FSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANPLKHKEWYALR 321
Cdd:COG4168  263 FSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKRKEWYALR 321
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 40-311 1.38e-46

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 159.54  E-value: 1.38e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498   40 LWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGF 119
Cdd:TIGR02789  64 LYVQYFHWLWNALHLDFGISYISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGV 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  120 SIPVFWLALLLTLFFSLTLGWLPVSGRfdllynvqtvsgfaivdawlsdsvwrdemivSALRHMVLPVLTLAVAPTTEVI 199
Cdd:TIGR02789 144 SIPNFWLAFLLVWGFSVYLNLLPTNGA-------------------------------GTWQHLVLPAVTLALMSVSIYA 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  200 RLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQQ 279
Cdd:TIGR02789 193 RLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHIGELLGGTFVIENIFSWPGVGRYAISAIFNR 272

                         250       260       270
                  ....*....|....*....|....*....|..
gi 515952498  280 DYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:TIGR02789 273 DYPVIQCYTLLMGLLFVFCNLIVDLFQALLDP 304
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 92-311 3.86e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 3.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498   92 GIPVGMLAGIYRNKWQDKFISALALIGFSIPVFWLALLLTLFFsltlgwlpvsgrfdllynvqtvsgfaivdawlsdsvw 171
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------------------- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  172 rdemIVSALRHMVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFST 251
Cdd:pfam00528  44 ----ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  252 MLTLAMITEMVFSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-297 2.87e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  74 FPATMELCILAFGFALMVGIPVGMLAGIYRNKWqDKFISALALIGFSIPVFwlallltlffsltlgwlpvsgrfdllynv 153
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSL----------------------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 154 qtVSGFAIVdawlsdSVWRDEMIVSALRHMVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHV 233
Cdd:cd06261   51 --VLGLLLV------LLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRII 122

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515952498 234 LHNALPPVIPRLGLQFSTMLTLAMITEMVFS----WPGLGRWMINAIRQQDYAAISAGVMVIGSLVII 297
Cdd:cd06261  123 LPLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PRK15110 PRK15110
peptide ABC transporter permease SapB;
23-321 0e+00

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 551.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  23 GFSLSYFTPHAPLQGSSLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIY 102
Cdd:PRK15110  23 GFSLSYFTPHAPLQGASLWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 103 RNKWQDKFISALALIGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYNVQTVSGFAIVDAWLSDSVWRDEMIVSALRH 182
Cdd:PRK15110 103 RHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFALIDAWLSDSPWRDEMIMSAIRH 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 183 MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262
Cdd:PRK15110 183 MILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515952498 263 FSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANPLKHKEWYALR 321
Cdd:PRK15110 263 FSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKHKEWYALR 321
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
23-321 6.72e-175

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 487.04  E-value: 6.72e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  23 GFSLSYFTPHAPLQGSSLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIY 102
Cdd:COG4168   23 SFSLLYRDPLNPLSDASLFSGYLFYLQNLLQGDFGISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIY 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 103 RNKWQDKFISALALIGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYNVQTVSGFAIVDAWLSDSVWRDEMIVSALRH 182
Cdd:COG4168  103 RGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYEIPPVTGFALIDAWLSDSPYRLKAIQSALQH 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 183 MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMV 262
Cdd:COG4168  183 LILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVV 262

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 515952498 263 FSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANPLKHKEWYALR 321
Cdd:COG4168  263 FSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKRKEWYALR 321
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 39-311 4.16e-77

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 238.43  E-value: 4.16e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  39 SLWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIG 118
Cdd:COG0601   60 PLLVQYLDWLGGLLRGDLGTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLG 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 119 FSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLynvqtvsgfaivdawlsdsvwrdEMIVSALRHMVLPVLTLAVAPTTEV 198
Cdd:COG0601  140 ISIPSFWLGLLLILLFAVKLGWLPVSGRVSPW-----------------------EDFLDALRHLILPALTLALGSLAGI 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 199 IRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQ 278
Cdd:COG0601  197 ARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILN 276

                        250       260       270
                 ....*....|....*....|....*....|...
gi 515952498 279 QDYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:COG0601  277 RDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDP 309
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
40-316 3.30e-54

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 180.39  E-value: 3.30e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  40 LWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGF 119
Cdd:PRK10914  62 MWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGY 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 120 SIPVFWLALLLTLFFSLTLGWLPVSGRFD---LLYNVQTVSGFAIVDAwlsdSVWRDEM-IVSALRHMVLPVLTLAVAPT 195
Cdd:PRK10914 142 SMPIFWWGMMLIMLVSVHWNLTPVSGRVSdmvFLDDSNPLTGFMLIDT----AIWGEDGnFIDAVAHMILPAIVLGTIPL 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 196 TEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINA 275
Cdd:PRK10914 218 AVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDA 297

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 515952498 276 IRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANP-LKHKE 316
Cdd:PRK10914 298 LQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPrIRHKK 339
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 40-311 1.38e-46

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 159.54  E-value: 1.38e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498   40 LWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGF 119
Cdd:TIGR02789  64 LYVQYFHWLWNALHLDFGISYISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGV 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  120 SIPVFWLALLLTLFFSLTLGWLPVSGRfdllynvqtvsgfaivdawlsdsvwrdemivSALRHMVLPVLTLAVAPTTEVI 199
Cdd:TIGR02789 144 SIPNFWLAFLLVWGFSVYLNLLPTNGA-------------------------------GTWQHLVLPAVTLALMSVSIYA 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  200 RLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQQ 279
Cdd:TIGR02789 193 RLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHIGELLGGTFVIENIFSWPGVGRYAISAIFNR 272

                         250       260       270
                  ....*....|....*....|....*....|..
gi 515952498  280 DYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:TIGR02789 273 DYPVIQCYTLLMGLLFVFCNLIVDLFQALLDP 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 40-311 1.43e-39

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 141.37  E-value: 1.43e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  40 LWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGF 119
Cdd:PRK10352  64 LYVQYGTWLWKALHLDFGISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGV 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 120 SIPVFWLALLLTLFFSLTLGWLPVSGRfdllynvqtvsgfaivdawlsdsvwrdemivSALRHMVLPVLTLAVAPTTEVI 199
Cdd:PRK10352 144 SMPNFWLAFLLVMAFSVYLQWLPAMGY-------------------------------GGWQHIILPAVSIAFMSLAINA 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 200 RLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQQ 279
Cdd:PRK10352 193 RLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNR 272

                        250       260       270
                 ....*....|....*....|....*....|..
gi 515952498 280 DYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:PRK10352 273 DYPVIQCFTLMMVVVFVVCNLIVDLLNAALDP 304
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 40-311 7.98e-38

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 136.38  E-value: 7.98e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  40 LWDAWLFWFNGLLHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGF 119
Cdd:PRK15081  61 LPHQFWHYISNALQGDFGTSMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGI 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 120 SIPVFWLALLLTLFFSLTLGWLPVSGrfdllynvqtvsgfaiVDAWlsdsvwrdemivsalRHMVLPVLTLAVAPTTEVI 199
Cdd:PRK15081 141 SFPAFALGMLLMQVFSVELGWLPTVG----------------ADSW---------------QHYILPSLTLGAAVAAVMA 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 200 RLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQQ 279
Cdd:PRK15081 190 RFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMR 269

                        250       260       270
                 ....*....|....*....|....*....|..
gi 515952498 280 DYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:PRK15081 270 DYPVIQAEVLLFSLEFILINLVVDVLYAAINP 301
oppB PRK09471
oligopeptide ABC transporter permease OppB;
40-311 1.68e-30

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 117.09  E-value: 1.68e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  40 LWDAWLFWFNGLLHWDFGVS-SINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIG 118
Cdd:PRK09471  59 IMTQYFSYLKQLAHGDFGPSfKYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTG 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 119 FSIPVFWLALLLTLFFSLTLGWLPVSGrfdllynvqtvsgfaivdawlsdsvWRDemivSALRHMVLPVLTLAVAPTTEV 198
Cdd:PRK09471 139 VVIPSFVVAPLLVLIFAITLHWLPGGG-------------------------WNG----GALKFMILPMVALSLAYIASI 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 199 IRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQ 278
Cdd:PRK09471 190 ARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALN 269

                        250       260       270
                 ....*....|....*....|....*....|...
gi 515952498 279 QDYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:PRK09471 270 RDYSLVLSLTILVGALTILFNAIVDVLYAVIDP 302
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 92-311 3.86e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 3.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498   92 GIPVGMLAGIYRNKWQDKFISALALIGFSIPVFWLALLLTLFFsltlgwlpvsgrfdllynvqtvsgfaivdawlsdsvw 171
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA------------------------------------- 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  172 rdemIVSALRHMVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFST 251
Cdd:pfam00528  44 ----ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  252 MLTLAMITEMVFSWPGLGRWMINAIRQQDYAAISAGVMVIGSLVIIVNVISDILGAMANP 311
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-297 2.87e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 2.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  74 FPATMELCILAFGFALMVGIPVGMLAGIYRNKWqDKFISALALIGFSIPVFwlallltlffsltlgwlpvsgrfdllynv 153
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSL----------------------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 154 qtVSGFAIVdawlsdSVWRDEMIVSALRHMVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHV 233
Cdd:cd06261   51 --VLGLLLV------LLFGVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRII 122

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515952498 234 LHNALPPVIPRLGLQFSTMLTLAMITEMVFS----WPGLGRWMINAIRQQDYAAISAGVMVIGSLVII 297
Cdd:cd06261  123 LPLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 52-311 1.47e-13

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 70.55  E-value: 1.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  52 LHWDFGVSSINGQLISEQLKVVFPATMELCILAFGFALMVGIPVGMLAGIYRNKWQDKFISALALIGFSIPVFWLALLLT 131
Cdd:PRK15133 111 IRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFDVWSSAFIIIGYAIPAFLFAILLI 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 132 LFFS--LTLGWLP----VSGRFDLLynvqtvsgfaivdAWLSDsvwrdemIVSALRHMVLPVLTLAVAPTTEVIRLMRIS 205
Cdd:PRK15133 191 VFFAggSYFDLFPlrglVSANFDSL-------------PWYQK-------ITDYLWHITLPVLATVIGGFAALTMLTKNS 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 206 TIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTM-LTLAMITEMVFSWPGLGRWMINAIRQQDYaAI 284
Cdd:PRK15133 251 FLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFSLNGLGLLGYEATVSRDY-PV 329

                        250       260
                 ....*....|....*....|....*...
gi 515952498 285 SAGVMVIGSLV-IIVNVISDILGAMANP 311
Cdd:PRK15133 330 MFGTLYIFTLIgLLLNIVSDISYTLVDP 357
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 77-305 5.51e-10

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 5.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498  77 TMELCILAFGFALMVGIPVGMLAGiYRNKWQDKFISALALIGFSIPVFwlallltlffsltlgwlpvsgrfdLLynvqtv 156
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAG-YFGGWVDAVLMRLVDVLLAFPSL------------------------LL------ 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 157 sgfAIVdawlsdsvwrdemIVSALRH-MVLPVLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLH 235
Cdd:COG1173  130 ---AIA-------------LVAVLGPgLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILP 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 236 NALPPVIPRLGLQFSTmltlAMITEMVFSWPGLGR------W--MINA----IRQQDYAAISAGVMvIGSLVIIVNVISD 303
Cdd:COG1173  194 NVLPPLIVQATLGIAS----AILAEAGLSFLGLGVqpptpsWgtMLSEgrnyLLTAPWLALFPGLA-IVLTVLAFNLLGD 268


                 ..
gi 515952498 304 IL 305
Cdd:COG1173  269 GL 270
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 211-301 3.59e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 47.45  E-value: 3.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 211 DQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWMINAIRQQDYAAISAGVMV 290
Cdd:COG0600  152 DPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILV 231

                         90
                 ....*....|.
gi 515952498 291 IGSLVIIVNVI 301
Cdd:COG0600  232 IGLLGLLLDLL 242
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
187-256 4.41e-06

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 47.50  E-value: 4.41e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515952498 187 VLTLAVAPTTEVIRLMRISTIDVFDQNYVKAAATRGLSRLTILRRHVLHNALPPVIPRLGLQFSTMLTLA 256
Cdd:PRK09881 160 MLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMA 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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