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Conserved domains on  [gi|522084708|ref|WP_020595917|]
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transposase, partial [Spirosoma panaciterrae]

Protein Classification

transposase family protein( domain architecture ID 229386)

transposase family protein may bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3335 super family cl41994
Transposase [Mobilome: prophages, transposons];
2-81 8.84e-20

Transposase [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG3335:

Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 80.68  E-value: 8.84e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522084708   2 TVIVLDNARIHTAGYIQGMrpiWEARGLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDLAYALNRCLVNVGRK 81
Cdd:COG3335  201 IVVILDNASFHKSKAVREW---LEEAGIELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSKDELKAAVRSFLDRISPD 277
 
Name Accession Description Interval E-value
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
2-81 8.84e-20

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 80.68  E-value: 8.84e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522084708   2 TVIVLDNARIHTAGYIQGMrpiWEARGLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDLAYALNRCLVNVGRK 81
Cdd:COG3335  201 IVVILDNASFHKSKAVREW---LEEAGIELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSKDELKAAVRSFLDRISPD 277
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
 2-67 6.74e-14

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 62.30  E-value: 6.74e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 522084708    2 TVIVLDNARIHTAGYIQGMRPIWEARgLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDL 67
Cdd:pfam13358  81 IVLVLDNASYHKSKAVRELVEAEADG-LELHYLPPYSPELNPIEILWSVLKRELLNNRRFKDLEEL 145
transpos_IS630 NF033545
IS630 family transposase;
3-75 4.20e-13

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 62.66  E-value: 4.20e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 522084708   3 VIVLDNARIHTAGYIQGmrpiWEAR--GLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDLAYALNRCL 75
Cdd:NF033545 226 HLILDNASTHKSKKVRE----WLEEhgRIELHYLPPYSPWLNPIERVWAVLKRRLLRNRAFRSVDELREAIDAFL 296
 
Name Accession Description Interval E-value
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
2-81 8.84e-20

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 80.68  E-value: 8.84e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522084708   2 TVIVLDNARIHTAGYIQGMrpiWEARGLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDLAYALNRCLVNVGRK 81
Cdd:COG3335  201 IVVILDNASFHKSKAVREW---LEEAGIELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSKDELKAAVRSFLDRISPD 277
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
 2-67 6.74e-14

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 62.30  E-value: 6.74e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 522084708    2 TVIVLDNARIHTAGYIQGMRPIWEARgLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDL 67
Cdd:pfam13358  81 IVLVLDNASYHKSKAVRELVEAEADG-LELHYLPPYSPELNPIEILWSVLKRELLNNRRFKDLEEL 145
transpos_IS630 NF033545
IS630 family transposase;
3-75 4.20e-13

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 62.66  E-value: 4.20e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 522084708   3 VIVLDNARIHTAGYIQGmrpiWEAR--GLYLFFLPAYCPHLNLAETLWRHLKGGWLRPEDYLTSDDLAYALNRCL 75
Cdd:NF033545 226 HLILDNASTHKSKKVRE----WLEEhgRIELHYLPPYSPWLNPIERVWAVLKRRLLRNRAFRSVDELREAIDAFL 296
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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