chromosome partition protein MukF, together with MukB and MukE, plays an important role in chromosome condensation and segregation during cell division
bacterial condensin complex subunit MukF, C-terminal domain; MukF is part of the MukBEF ...
1-439
0e+00
bacterial condensin complex subunit MukF, C-terminal domain; MukF is part of the MukBEF condensin complex that is mainly found in proteobacteria and is involved in chromosome organization and condensation. The complex is believed to serve as a part of the chromosome scaffold rather than a bulk DNA packing protein. MukE and MukF form a stable complex with each other and dynamically associate with MukB, a member of the SMC protein family. MukEF does not bind DNA on its own but modulates MukB-DNA activity. The stoichiometry of the MukEF complex is MukE4F2.
The actual alignment was detected with superfamily member COG3006:
Pssm-ID: 478215 Cd Length: 440 Bit Score: 724.10 E-value: 0e+00
bacterial condensin complex subunit MukF, N-terminal domain; MukF is part of the MukBEF ...
13-326
1.05e-109
bacterial condensin complex subunit MukF, N-terminal domain; MukF is part of the MukBEF condensin complex that is mainly found in proteobacteria and is involved in chromosome organization and condensation. The complex is believed to serve as a part of the chromosome scaffold rather than a bulk DNA packing protein. MukE and MukF form a stable complex with each other and dynamically associate with MukB, a member of the SMC protein family. MukEF does not bind DNA on its own but modulates MukB-DNA activity. The stoichiometry of the MukEF complex is MukE4F2.
Pssm-ID: 319981 Cd Length: 315 Bit Score: 326.14 E-value: 1.05e-109
MukF middle domain; The kicA and kicB genes are found upstream of mukB. It has been suggested ...
119-279
3.63e-91
MukF middle domain; The kicA and kicB genes are found upstream of mukB. It has been suggested that the kicB gene encodes a killing factor and the kicA gene codes for a protein that suppresses the killing function of the kicB gene product. It was also demonstrated that KicA and KicB can function as a post-segregational killing system, when the genes are transferred from the E. coli chromosome onto a plasmid.
Pssm-ID: 407317 Cd Length: 161 Bit Score: 272.77 E-value: 3.63e-91
bacterial condensin complex subunit MukF, N-terminal domain; MukF is part of the MukBEF ...
13-326
1.05e-109
bacterial condensin complex subunit MukF, N-terminal domain; MukF is part of the MukBEF condensin complex that is mainly found in proteobacteria and is involved in chromosome organization and condensation. The complex is believed to serve as a part of the chromosome scaffold rather than a bulk DNA packing protein. MukE and MukF form a stable complex with each other and dynamically associate with MukB, a member of the SMC protein family. MukEF does not bind DNA on its own but modulates MukB-DNA activity. The stoichiometry of the MukEF complex is MukE4F2.
Pssm-ID: 319981 Cd Length: 315 Bit Score: 326.14 E-value: 1.05e-109
MukF middle domain; The kicA and kicB genes are found upstream of mukB. It has been suggested ...
119-279
3.63e-91
MukF middle domain; The kicA and kicB genes are found upstream of mukB. It has been suggested that the kicB gene encodes a killing factor and the kicA gene codes for a protein that suppresses the killing function of the kicB gene product. It was also demonstrated that KicA and KicB can function as a post-segregational killing system, when the genes are transferred from the E. coli chromosome onto a plasmid.
Pssm-ID: 407317 Cd Length: 161 Bit Score: 272.77 E-value: 3.63e-91
MukF winged-helix domain; The kicA and kicB genes are found upstream of mukB. It has been ...
3-115
2.37e-60
MukF winged-helix domain; The kicA and kicB genes are found upstream of mukB. It has been suggested that the kicB gene encodes a killing factor and the kicA gene codes for a protein that suppresses the killing function of the kicB gene product. It was also demonstrated that KicA and KicB can function as a post-segregational killing system, when the genes are transferred from the E. coli chromosome onto a plasmid.
Pssm-ID: 397801 [Multi-domain] Cd Length: 115 Bit Score: 192.26 E-value: 2.37e-60
bacterial condensin complex subunit MukF, C-terminal domain; MukF is part of the MukBEF ...
340-437
9.31e-32
bacterial condensin complex subunit MukF, C-terminal domain; MukF is part of the MukBEF condensin complex that is mainly found in proteobacteria and is involved in chromosome organization and condensation. The complex is believed to serve as a part of the chromosome scaffold rather than a bulk DNA packing protein. MukE and MukF form a stable complex with each other and dynamically associate with MukB, a member of the SMC protein family. MukEF does not bind DNA on its own but modulates MukB-DNA activity. The stoichiometry of the MukEF complex is MukE4F2.
Pssm-ID: 319979 [Multi-domain] Cd Length: 97 Bit Score: 116.64 E-value: 9.31e-32
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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