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Conserved domains on  [gi|1328066418|ref|WP_102183280|]
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DUF1636 domain-containing protein [Fischerella thermalis]

Protein Classification

DUF1636 domain-containing protein( domain architecture ID 10545172)

DUF1636 domain-containing protein may be a metal-binding protein with similarity to thioredoxin-like [2Fe-2S] ferredoxin

CATH:  3.40.30.10
PubMed:  10049365|15558583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1636 pfam07845
Protein of unknown function (DUF1636); The sequences featured in this family are derived from ...
 23-138 4.91e-71

Protein of unknown function (DUF1636); The sequences featured in this family are derived from a number of hypothetical prokaryotic proteins. The region in question is approximately 130 amino acids long.


:

Pssm-ID: 429694  Cd Length: 117  Bit Score: 208.59  E-value: 4.91e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  23 LFVCKTCASVWQDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGKLTYMFGDLPVDDSA 102
Cdd:pfam07845   1 LFVCTTCRSSWDDGDRDGPRGGARLLEALQALLQNWALPAEVEIQPVECLSACDRPCAVALAAPGKWTYVFGDLPPEESA 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1328066418 103 AAILECASKYYDKSDGLLPWSERPEPLKKGILARIP 138
Cdd:pfam07845  81 AALLEFAALYAASPDGLVPWRERPEGLRKGILARIP 116
 
Name Accession Description Interval E-value
DUF1636 pfam07845
Protein of unknown function (DUF1636); The sequences featured in this family are derived from ...
 23-138 4.91e-71

Protein of unknown function (DUF1636); The sequences featured in this family are derived from a number of hypothetical prokaryotic proteins. The region in question is approximately 130 amino acids long.


Pssm-ID: 429694  Cd Length: 117  Bit Score: 208.59  E-value: 4.91e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  23 LFVCKTCASVWQDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGKLTYMFGDLPVDDSA 102
Cdd:pfam07845   1 LFVCTTCRSSWDDGDRDGPRGGARLLEALQALLQNWALPAEVEIQPVECLSACDRPCAVALAAPGKWTYVFGDLPPEESA 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1328066418 103 AAILECASKYYDKSDGLLPWSERPEPLKKGILARIP 138
Cdd:pfam07845  81 AALLEFAALYAASPDGLVPWRERPEGLRKGILARIP 116
COG5469 COG5469
Predicted metal-binding protein [Function unknown];
19-141 1.01e-70

Predicted metal-binding protein [Function unknown];


Pssm-ID: 444220  Cd Length: 128  Bit Score: 208.23  E-value: 1.01e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  19 PSHTLFVCKTCASVWQDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGKLTYMFGDLPV 98
Cdd:COG5469     3 AKHTLFVCTTCRRSGDDREGMGPRPGAQLLEALRAAAAAWGLPEGVEIQPVECLSACSRPCTVALSAPGKWTYLFGDLDP 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1328066418  99 DDSAAAILECASKYYDKSDGLLPWSERPEPLKKGILARIPSLS 141
Cdd:COG5469    83 DEDAEDLLEFAALYAASEDGLVPWRERPEGLRKGILARIPPLP 125
TRX_Fd_family cd02980
Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX ...
 21-107 6.79e-07

Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.


Pssm-ID: 239278 [Multi-domain]  Cd Length: 77  Bit Score: 44.16  E-value: 6.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  21 HTLFVCktcasvwqDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGkltYMFGDLPVDD 100
Cdd:cd02980     1 HHILVC--------TGTACGLRGAEELLEALEKELGIRGGDGRVTVERVGCLGACGLAPVVVVYPDG---VWYGRVTPED 69


                  ....*..
gi 1328066418 101 sAAAILE 107
Cdd:cd02980    70 -VEEIVE 75
 
Name Accession Description Interval E-value
DUF1636 pfam07845
Protein of unknown function (DUF1636); The sequences featured in this family are derived from ...
 23-138 4.91e-71

Protein of unknown function (DUF1636); The sequences featured in this family are derived from a number of hypothetical prokaryotic proteins. The region in question is approximately 130 amino acids long.


Pssm-ID: 429694  Cd Length: 117  Bit Score: 208.59  E-value: 4.91e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  23 LFVCKTCASVWQDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGKLTYMFGDLPVDDSA 102
Cdd:pfam07845   1 LFVCTTCRSSWDDGDRDGPRGGARLLEALQALLQNWALPAEVEIQPVECLSACDRPCAVALAAPGKWTYVFGDLPPEESA 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1328066418 103 AAILECASKYYDKSDGLLPWSERPEPLKKGILARIP 138
Cdd:pfam07845  81 AALLEFAALYAASPDGLVPWRERPEGLRKGILARIP 116
COG5469 COG5469
Predicted metal-binding protein [Function unknown];
19-141 1.01e-70

Predicted metal-binding protein [Function unknown];


Pssm-ID: 444220  Cd Length: 128  Bit Score: 208.23  E-value: 1.01e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  19 PSHTLFVCKTCASVWQDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGKLTYMFGDLPV 98
Cdd:COG5469     3 AKHTLFVCTTCRRSGDDREGMGPRPGAQLLEALRAAAAAWGLPEGVEIQPVECLSACSRPCTVALSAPGKWTYLFGDLDP 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1328066418  99 DDSAAAILECASKYYDKSDGLLPWSERPEPLKKGILARIPSLS 141
Cdd:COG5469    83 DEDAEDLLEFAALYAASEDGLVPWRERPEGLRKGILARIPPLP 125
TRX_Fd_family cd02980
Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX ...
 21-107 6.79e-07

Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.


Pssm-ID: 239278 [Multi-domain]  Cd Length: 77  Bit Score: 44.16  E-value: 6.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1328066418  21 HTLFVCktcasvwqDGKRVGESGGQKLLKQLQELAQDWHLKDDFPIQEVECMSACSHSCVVAFAGSGkltYMFGDLPVDD 100
Cdd:cd02980     1 HHILVC--------TGTACGLRGAEELLEALEKELGIRGGDGRVTVERVGCLGACGLAPVVVVYPDG---VWYGRVTPED 69


                  ....*..
gi 1328066418 101 sAAAILE 107
Cdd:cd02980    70 -VEEIVE 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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