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Conserved domains on  [gi|1840107283|ref|WP_170128461|]
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transposase, partial [Thermosipho africanus]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-53 3.89e-14

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 62.25  E-value: 3.89e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1840107283   2 RKREKYSSDFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEESGYD 53
Cdd:COG2963     3 KKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLG 54
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-53 3.89e-14

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 62.25  E-value: 3.89e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1840107283   2 RKREKYSSDFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEESGYD 53
Cdd:COG2963     3 KKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLG 54
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-49 1.78e-10

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 52.36  E-value: 1.78e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1840107283   1 MRKREKYSSDFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEE 49
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEG 49
transpos_IS3 NF033516
IS3 family transposase;
10-51 1.77e-09

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 52.95  E-value: 1.77e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1840107283  10 DFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEESG 51
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGG 42
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-53 3.89e-14

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 62.25  E-value: 3.89e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1840107283   2 RKREKYSSDFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEESGYD 53
Cdd:COG2963     3 KKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLG 54
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-49 1.78e-10

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 52.36  E-value: 1.78e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1840107283   1 MRKREKYSSDFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEE 49
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEG 49
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 11-65 3.10e-10

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 51.05  E-value: 3.10e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1840107283  11 FKLQVVKEYLnSDKSQNDICSEYNISQSAFSRWVKKYEESGYDDnvFNSKKGRPK 65
Cdd:pfam13518   1 ERLKIVLLAL-EGESIKEAARLFGISRSTVYRWIRRYREGGLEG--LLPRRRRPK 52
transpos_IS3 NF033516
IS3 family transposase;
10-51 1.77e-09

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 52.95  E-value: 1.77e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1840107283  10 DFKLQVVKEYLNSDKSQNDICSEYNISQSAFSRWVKKYEESG 51
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGG 42
HTH_23 pfam13384
Homeodomain-like domain;
12-54 1.04e-04

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 36.86  E-value: 1.04e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1840107283  12 KLQVVKEYLNsDKSQNDICSEYNISQSAFSRWVKKYEESGYDD 54
Cdd:pfam13384   7 RARALLLLAE-GLSVKEIAELLGVSRRTVYRWLKRYNEEGLEG 48
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 12-67 2.64e-04

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 38.29  E-value: 2.64e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1840107283  12 KLQVVKEYLnSDKSQNDICSEYNISQSAFSRWVKKYEESGYDDNVFNSKKGRPKSI 67
Cdd:COG3415    28 RLRAVLLLA-EGLSVREIAERLGVSRSTVYRWLKRYREGGLAGLKDRPRGGRPSKL 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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