|
Name |
Accession |
Description |
Interval |
E-value |
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 751.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 3 STVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 83 IDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLE 161
Cdd:COG0104 81 IDGLEARGVdVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 162 TALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 242 CTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASR 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTEL--FDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 322 VNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAF 401
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVER 398
|
410 420
....*....|....*....|....
gi 2796504268 402 IEDLAHTRVTFIGVGAGREQIINR 425
Cdd:COG0104 399 IEELLGVPISIVSVGPDREQTIVR 422
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-423 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 741.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 81 EEIDMFEADGITTK-NLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDK 159
Cdd:PRK01117 81 KEIDELEARGVDVReRLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 160 LETALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 240 SNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYA 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTEL--FDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 320 SRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYV 399
Cdd:PRK01117 319 VRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYI 398
|
410 420
....*....|....*....|....
gi 2796504268 400 AFIEDLAHTRVTFIGVGAGREQII 423
Cdd:PRK01117 399 KRIEELTGVPISIISTGPDRDQTI 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-423 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 729.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEID 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 85 MFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:pfam00709 81 ELEERGIdVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPELELIYNlPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNCT 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 244 AGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRVN 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTEL--FDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRIN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 324 GLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAFIE 403
Cdd:pfam00709 318 GVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 2796504268 404 DLAHTRVTFIGVGAGREQII 423
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 676.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 3 STVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 83 IDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEqklgKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLE 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKARE----KARIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 162 TALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 242 CTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASR 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELF--DETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 322 VNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAF 401
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIER 394
|
410 420
....*....|....*....|..
gi 2796504268 402 IEDLAHTRVTFIGVGAGREQII 423
Cdd:smart00788 395 IEELVGVPVSIISTGPDREQTI 416
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-423 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 514.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEID 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 85 MFEADGITTKN-LKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:TIGR00184 81 YLEKRGISVRDrLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNCT 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 244 AGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRVN 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELS--DEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 324 GLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAFIE 403
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIE 398
|
410 420
....*....|....*....|
gi 2796504268 404 DLAHTRVTFIGVGAGREQII 423
Cdd:TIGR00184 399 ELTGVPVTIISTGPEREQTI 418
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-423 |
1.09e-171 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 483.15 E-value: 1.09e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 2 PSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 82 EIDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDmldetlfrdkl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 161 etalarvnpeleliynlptytvdqicdeylpmaerlrPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 241 NCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYAS 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTEL--FDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAV 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 321 RVNGLTDIAMTKLDVlsafdtikvcvaydvdgerytsvpehqvrfehakpiyeelpgwkcditgcrsfdelpqEAQDYVA 400
Cdd:cd03108 271 RINGLTELALTKLDV----------------------------------------------------------NAQKYIE 292
|
410 420
....*....|....*....|...
gi 2796504268 401 FIEDLAHTRVTFIGVGAGREQII 423
Cdd:cd03108 293 RIEELLGVPITYISVGPDREQTI 315
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-324 |
8.11e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.17 E-value: 8.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 4 TVLVGAQWGDEGKGKICD-LVAGD-FDAVVRySGGNNAGHTiVVN--GKKYGLHQVPSGIMYSDHVSV-IGNGCVVNPKV 78
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGyLAERAaPDVVVR-AAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 79 VLEEIDMFEADG-ITTKNLKISGNAHVImPYHIDLDGafEQKLGKKnIGTTKRGIGPCYQDKMARiglrmqdmldetlfr 157
Cdd:NF038379 80 LREEIEELEDAGhDVGKRLLIHEQATVI-ELHKHVEE--EAGPMTK-IGSTKKGIGAARAAKIRR--------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 158 dkletalarvNPELELIYnlptytVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYV 237
Cdd:NF038379 141 ----------NPSTLGDA------EGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYPYC 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 238 TSSNCTAGGAITGSGVGMKNVD--RVLGVMKAYITRVG-----SGPMPTELSYEsEAGhtLTEegyEYGVTTGRRRRCGW 310
Cdd:NF038379 205 TSRDCTPADFLADAGIPLPNVDafKVVGTARTYPIRVAgwsgnSYPDQGETTWE-ELG--LPE---ELTTVTKKVRRVGT 278
|
330
....*....|....
gi 2796504268 311 FDGPIANYASRVNG 324
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 751.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 3 STVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 83 IDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLE 161
Cdd:COG0104 81 IDGLEARGVdVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 162 TALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 242 CTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASR 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTEL--FDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 322 VNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAF 401
Cdd:COG0104 319 INGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVER 398
|
410 420
....*....|....*....|....
gi 2796504268 402 IEDLAHTRVTFIGVGAGREQIINR 425
Cdd:COG0104 399 IEELLGVPISIVSVGPDREQTIVR 422
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-423 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 741.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 81 EEIDMFEADGITTK-NLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDK 159
Cdd:PRK01117 81 KEIDELEARGVDVReRLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 160 LETALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 240 SNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYA 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTEL--FDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 320 SRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYV 399
Cdd:PRK01117 319 VRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYI 398
|
410 420
....*....|....*....|....
gi 2796504268 400 AFIEDLAHTRVTFIGVGAGREQII 423
Cdd:PRK01117 399 KRIEELTGVPISIISTGPDRDQTI 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-423 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 729.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEID 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 85 MFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:pfam00709 81 ELEERGIdVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPELELIYNlPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNCT 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 244 AGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRVN 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTEL--FDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRIN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 324 GLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAFIE 403
Cdd:pfam00709 318 GVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIE 397
|
410 420
....*....|....*....|
gi 2796504268 404 DLAHTRVTFIGVGAGREQII 423
Cdd:pfam00709 398 ELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 676.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 3 STVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 83 IDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEqklgKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLE 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKARE----KARIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 162 TALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 242 CTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASR 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELF--DETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 322 VNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAF 401
Cdd:smart00788 315 INGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIER 394
|
410 420
....*....|....*....|..
gi 2796504268 402 IEDLAHTRVTFIGVGAGREQII 423
Cdd:smart00788 395 IEELVGVPVSIISTGPDREQTI 416
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-423 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 514.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEID 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 85 MFEADGITTKN-LKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:TIGR00184 81 YLEKRGISVRDrLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNCT 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 244 AGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRVN 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELS--DEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 324 GLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAFIE 403
Cdd:TIGR00184 319 GATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIE 398
|
410 420
....*....|....*....|
gi 2796504268 404 DLAHTRVTFIGVGAGREQII 423
Cdd:TIGR00184 399 ELTGVPVTIISTGPEREQTI 418
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-423 |
1.09e-171 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 483.15 E-value: 1.09e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 2 PSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLE 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 82 EIDMFEADGI-TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDmldetlfrdkl 160
Cdd:cd03108 81 EIEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 161 etalarvnpeleliynlptytvdqicdeylpmaerlrPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 241 NCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYAS 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTEL--FDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAV 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 321 RVNGLTDIAMTKLDVlsafdtikvcvaydvdgerytsvpehqvrfehakpiyeelpgwkcditgcrsfdelpqEAQDYVA 400
Cdd:cd03108 271 RINGLTELALTKLDV----------------------------------------------------------NAQKYIE 292
|
410 420
....*....|....*....|...
gi 2796504268 401 FIEDLAHTRVTFIGVGAGREQII 423
Cdd:cd03108 293 RIEELLGVPITYISVGPDREQTI 315
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
4-425 |
7.73e-171 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 485.69 E-value: 7.73e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 4 TVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEI 83
Cdd:PTZ00350 15 VVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 84 DMFEADGITTKN-LKISGNAHVIMPYHIDLDGAFEQKLGKKN--IGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKL 160
Cdd:PTZ00350 95 EQLTKKGINLLGrLYISDRAHLVFDLHQAIDGIQESEKGKGGtqIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 161 etalARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSS 240
Cdd:PTZ00350 175 ----RKLVEKLQEQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSS 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 241 NCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYAS 320
Cdd:PTZ00350 251 NTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELF--DENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 321 RVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYT--SVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDY 398
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGLEigRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKY 408
|
410 420
....*....|....*....|....*..
gi 2796504268 399 VAFIEDLAHTRVTFIGVGAGREQIINR 425
Cdd:PTZ00350 409 VLFIEELLGVPIVWIGVGPNRENMIVK 435
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
5-426 |
7.78e-168 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 477.60 E-value: 7.78e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIV-VNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEI 83
Cdd:PLN02513 6 AVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGLFEEI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 84 DMFEADGITTKN-LKISGNAHVIMPYHIDLDGAFEQKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLET 162
Cdd:PLN02513 86 DGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAEKLRE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 163 ALARVNPELELiYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNC 242
Cdd:PLN02513 166 LLADAAARFEG-FEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVTSSNP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 243 TAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRV 322
Cdd:PLN02513 245 SAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTEL--FGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSCQI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 323 NGLTDIAMTKLDVLSAFDTIKVCVAYD-VDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVAF 401
Cdd:PLN02513 323 NGFTSLNLTKLDVLSGLPEIKIGVAYKtPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYVER 402
|
410 420
....*....|....*....|....*
gi 2796504268 402 IEDLAHTRVTFIGVGAGREQIINRF 426
Cdd:PLN02513 403 IEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
4-423 |
8.08e-158 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 452.33 E-value: 8.08e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 4 TVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVsVIGNGCVVNPKVVLEEI 83
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 84 DMFEADGI--TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKnIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLE 161
Cdd:PRK13786 82 DMLEKHGVkvDAEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 162 TALARVNPELELIYNLPTYTVDQ-ICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTSS 240
Cdd:PRK13786 161 ELAPQKEKEIKELGGDPSIVRDEaLIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 241 NCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYAS 320
Cdd:PRK13786 241 STIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTEL--KDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 321 RVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKCDITGCRSFDELPQEAQDYVA 400
Cdd:PRK13786 319 YLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVE 398
|
410 420
....*....|....*....|...
gi 2796504268 401 FIEDLAHTRVTFIGVGAGREQII 423
Cdd:PRK13786 399 RLEELMGVPIKYISVGPGREQTF 421
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-423 |
1.67e-144 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 418.20 E-value: 1.67e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 81 EEIDMFEADGITTKN-LKISGNAHVIMPYHIDLDGAFEQKLG-KKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRd 158
Cdd:PRK13787 81 EECDRLQKEGFPVKDkLLLSDACHLLFPYHSQIDSARETTSSqEHKIGTTKKGIGICYADKMMRTGLRVGDLLDKSYKR- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 159 KLETALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVT 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 239 SSNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANY 318
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELL--GEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKH 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 319 ASRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVrfEHAKPIYEELPGWKCDITGCRSFDELPQEAQDY 398
Cdd:PRK13787 318 SVRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQGL--EKVEPLYEEFPGWKDDISGINEFQKLPEKCKNY 395
|
410 420
....*....|....*....|....*
gi 2796504268 399 VAFIEDLAHTRVTFIGVGAGREQII 423
Cdd:PRK13787 396 ISALEKWIGVKINLVSTGPDRKDTI 420
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-421 |
4.10e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 403.80 E-value: 4.10e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 81 EEIDMFEADGITTKnLKISGNAHVIMPYHIDLDGafeqklGKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKL 160
Cdd:PRK13788 81 EERENLRAGGLNPK-LLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 161 ETAL-ARVNPELELIYNlptyTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVTS 239
Cdd:PRK13788 154 ERLLeAKPNSTREAGWD----TVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 240 SNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELsyESEAGHTLTEEG----YEYGVTTGRRRRCGWFDGPI 315
Cdd:PRK13788 230 SHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEV--FGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 316 ANYASRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGerytsvpehqvrfehaKPIYEELPGWKcDITGCRSFDELPQEA 395
Cdd:PRK13788 308 LKYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWG-DLDGVKSREALPKEA 370
|
410 420
....*....|....*....|....*.
gi 2796504268 396 QDYVAFIEDLAHTRVTFIGVGAGREQ 421
Cdd:PRK13788 371 QAYLELIEETTGVPVVMFSTSPRRED 396
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
5-423 |
4.49e-136 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 396.01 E-value: 4.49e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLEEID 84
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 85 MFEADGIT-TKNLKISGNAHVIMPYHIDLDGAFEQKLgKKNIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:PRK13783 84 ELKEKFPDySGRIFISELAHVVLPVHKELDEIIESVR-KNAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLEKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPelelIYNLpTYTVDQICDEYLPMAERLRPYITETSLLLNnmIDEGKDLLFEGAQATLLDIDHGTYPYVTSSNCT 243
Cdd:PRK13783 163 LSLYKK----LYGI-EFDVEKMMEDLLTFYEKIKDLVVSPVEIKR--ILEEKSVLFEGTQGVLLDLDVGTYPYVTSSNCS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 244 AGGAITGSGVGMKnVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANYASRVN 323
Cdd:PRK13783 236 TTGVSAGMGFPVK-VDEVIGVFKAYTTRVGEGPFPTELF--GEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVS 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 324 GLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSvPEHQVRFEHAKPIYEELPGWKcditgcrsfDELPQEAQDYVAFIE 403
Cdd:PRK13783 313 GVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWK---------SLEDKNFLKFVDFIE 382
|
410 420
....*....|....*....|
gi 2796504268 404 DLAHTRVTFIGVGAGREQII 423
Cdd:PRK13783 383 RETGRKIAYISTGPKIEEIV 402
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
6-425 |
1.40e-131 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 386.42 E-value: 1.40e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 6 LVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMySDHVSVIGNGCVVNPKVVLEEIDM 85
Cdd:PRK13785 5 IVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAV-RGKIGVLGNGCVVNPETLFDEIDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 86 FEADGITtKNLKISGNAHVIMPYHIDLDGAFEQKLGKKN--IGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRDKLETA 163
Cdd:PRK13785 84 LRERGLD-PDVRVAERAHVILPYHRVLDGIEEEAKSDSDleVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRLEYV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 164 LARVNPELELIYNLPT------YTVDQICDEYLPMAERLRP--YITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYP 235
Cdd:PRK13785 163 VPQKRALAEDVYGLDAsetpeaFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHGNYP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 236 YVTSSNCTAGGAITGSGVGMKNVDR--VLGVMKAYITRVGSGPMPTEL-------------SYESEAGHTLTEEGYEYGV 300
Cdd:PRK13785 243 YVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrPDEEELATYIREEGGEYGT 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 301 TTGRRRRCGWFDGPIANYASRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDGERYTSVPEHQVRFEHAKPIYEELPGWKC 380
Cdd:PRK13785 323 VTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFDGWPE 402
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 2796504268 381 ---DITGCRSFDELPQEAQDYVAFIEDLAHTRVTFIGVGAGREQIINR 425
Cdd:PRK13785 403 vdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-423 |
1.73e-106 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 321.58 E-value: 1.73e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVAGDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 81 EEIDMFEADGI--TTKNLKISGNAHVIMPYHIDLDGAFEQKLGKKnIGTTKRGIGPCYQDKMARIGLRMQDMLDETLFRD 158
Cdd:PRK13784 81 EEITRLQAKGIaiSAENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 159 KLETALARVNPELELIYNLPTYTVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 239 SSNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSyeSEAGHTLTEEGYEYGVTTGRRRRCGWFDGPIANY 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELF--DDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 319 ASRVNGLTDIAMTKLDVLSAFDTIKVCVAYDVDG-ERYTSVPehQVRFEHAKPIYEELPGWKCDITGCRsfDELPQEAQD 397
Cdd:PRK13784 318 SAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGkEIYCAYP--GIDLYKVEPILVEMEPFSIDETVTK--DNMPAALKT 393
|
410 420
....*....|....*....|....*.
gi 2796504268 398 YVAFIEDLAHTRVTFIGVGAGREQII 423
Cdd:PRK13784 394 YLKTIENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-425 |
1.39e-88 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 272.14 E-value: 1.39e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 1 MPSTVLVGAQWGDEGKGKICDLVA--GDFDAVVRYSGGNNAGHTIVVNGKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKV 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 79 VLEEIDMFEADGittkNLKISGNAHVIMPYHIDLDGAFEQkLGKKnIGTTKRGIGPCYQDKMARIGlrmqdmldetlfrd 158
Cdd:PRK04293 81 LLKEVEELNVGG----RVFVDYRCGIIEEKHVEEDRSDEH-LSKK-IGSTGTGCGPANADRVLRRL-------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 159 kletALARVNPELEliynlptytvdqicdeylpmaerlrPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYVT 238
Cdd:PRK04293 141 ----KLAKDVEELE-------------------------KYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVT 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 239 SSNCTAGGAITGSGVGMKNVDRVLGVMKAYITRVGSGPMPTELSYEsEAGhtltEEGY-EYGVTTGRRRRCGWFDGPIAN 317
Cdd:PRK04293 192 SKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLE-EAE----KLGLvEYGTVTGRRRRVGPFDFELAR 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 318 YASRVNGLTDIAMTKLDVLsafdtikvcvaydvdgerytsvpehqvrFEHAKpiyeelpgwkcditGCRSFDELPQEAQD 397
Cdd:PRK04293 267 RAARINGATQIAITKLDKL----------------------------DKEAY--------------GVTEYDKLPPEAKK 304
|
410 420
....*....|....*....|....*...
gi 2796504268 398 YVAFIEDLAHTRVTFIGVGAGREQIINR 425
Cdd:PRK04293 305 FIEEIEEELGVPVTLISTGPELEDTIDL 332
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-324 |
8.11e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.17 E-value: 8.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 4 TVLVGAQWGDEGKGKICD-LVAGD-FDAVVRySGGNNAGHTiVVN--GKKYGLHQVPSGIMYSDHVSV-IGNGCVVNPKV 78
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGyLAERAaPDVVVR-AAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 79 VLEEIDMFEADG-ITTKNLKISGNAHVImPYHIDLDGafEQKLGKKnIGTTKRGIGPCYQDKMARiglrmqdmldetlfr 157
Cdd:NF038379 80 LREEIEELEDAGhDVGKRLLIHEQATVI-ELHKHVEE--EAGPMTK-IGSTKKGIGAARAAKIRR--------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 158 dkletalarvNPELELIYnlptytVDQICDEYLPMAERLRPYITETSLLLNNMIDEGKDLLFEGAQATLLDIDHGTYPYV 237
Cdd:NF038379 141 ----------NPSTLGDA------EGDFGEGAVRDQPWEIAERVVDNALYDFALQAAERIQIEGTQGYSLGLHAGFYPYC 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 238 TSSNCTAGGAITGSGVGMKNVD--RVLGVMKAYITRVG-----SGPMPTELSYEsEAGhtLTEegyEYGVTTGRRRRCGW 310
Cdd:NF038379 205 TSRDCTPADFLADAGIPLPNVDafKVVGTARTYPIRVAgwsgnSYPDQGETTWE-ELG--LPE---ELTTVTKKVRRVGT 278
|
330
....*....|....
gi 2796504268 311 FDGPIANYASRVNG 324
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
5-423 |
2.69e-20 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 93.58 E-value: 2.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 5 VLVGAQWGDEGKGKICDLVAGD--FDAVVRYSGGNNAGHTIVVN-GKKYGLHQVPSGIMYSDHVSVIGNGCVVNPKVVLE 81
Cdd:PTZ00351 173 MVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFME 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 82 -EIDMFEADGITTKNLKISGNAHVIMPYHIDLDgafeqKLGKKNIGTTKRGIGPCYQDKMARIGLRMQDML--DETLfRD 158
Cdd:PTZ00351 253 kEIIQLIDAGIDYRDRLFIGNVCIVTPYHKLLD-----LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFndDETL-RK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 159 KLETALARVNPELElIYNLPTYTVDQIC------------DEYLPMAE--------------RLR-----PYITETSLLL 207
Cdd:PTZ00351 327 RLEKDMDTYLGLLK-VKNLSDADVVRLCreensdgvvrvpDYVIAFAQakdkveflvklyrdRVRhnpdfPARCDVTYEL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 208 NNMIDEGKDLLFEGAQATLLDIDHGTY-PYVTSSNCTAGGAITGSGVGMKNVDR-VLGVMKAY-ITRVGSGPMPT----- 279
Cdd:PTZ00351 406 HAAVLRGEKVLLEGPQSYWLSNARTKFwESTTSADTTAAGLLAASQLNFQKFKSvVLNVHKAPgSSRVGIGACPSsfvpq 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 280 ------------ELSYESEAG-----HTLTEEGYEY----------------------------------------GVTT 302
Cdd:PTZ00351 486 dyfsaqniktlrDLPSATCANfeavqRTLFRDGFPHsndkarhngimapveysdetgdynigvamaiasaqhhgecGAVT 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504268 303 GRRRRCGWFDGPIANYASRVNGlTDIAMTKLDVLSAFDTIKVCVAY----------DVDGERYTS---------VPEHQV 363
Cdd:PTZ00351 566 KKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAYvyynpegkqvDVNGHVYKNgdiiragdpVPSEPA 644
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2796504268 364 RFeHAKPIYEELPGWKCDITGC---RSFDELPQEAQDYVAFIEDLAHTRVTFIGVGAGREQII 423
Cdd:PTZ00351 645 LY-HCHPIVKLIDGWRDNPIAAakrRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDII 706
|
|
| |
