|
Name |
Accession |
Description |
Interval |
E-value |
| ClfA |
COG4932 |
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ... |
79-767 |
6.50e-39 |
|
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443959 [Multi-domain] Cd Length: 689 Bit Score: 155.52 E-value: 6.50e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 79 TKPGGPWLNFDQGWVWLDDEFAAIVCHGYPTATSFGGYHLSPDRARAATQLAVWMLNGTTHVDGTYSYTTAQGKTKSGHF 158
Cdd:COG4932 3 GAKGAGTGVGTVIVEGAGSGSLVAVTTGAVLGLALGSTGGTAGSAAAINSAPATGTATGTSAGATAVIVIAAGLTATPTE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 159 TADNEVVAAARWLHDSAKSGSIKAAPHRARRYLGAVSGGSKRQDMLYVLPAVSVSFQKQSANTV---------------- 222
Cdd:COG4932 83 TASGLGGDATVTTTANVAKVTNGAAANLTVNADGTASNAGTLAKGAETATGNLDGDAGDVTVTAaatdgvndvdgngasv 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 223 --------ITSGNNTYQFTGATFDIFeSASGARVGTIKMDSNGRAQATLLPNTAYYLVETKAPAGYV-----PRHDRIAF 289
Cdd:COG4932 163 tdsvtlkkVDDGDTGKPLPGATFTLY-DSDGTLVKTVTTDADGKYTFTDLPPGTYTLTETKAPEGYVldtkdPTGATITV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 290 TTGNDGGR---VAIDEQPGTINLRIVKLDAATnagpqvGSSLAGAEFTCVSQS--TPGWAQILTTDESGRATLADVPLGT 364
Cdd:COG4932 242 TVNAGGTVtvtLKNTPKYTKGSVTVTKTDADT------GEPLAGATFTLTDADgnTVVTTTVTVTDADGSYTFTDLPPGT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 365 FTIYESKTPEGYLPSNDSWTYTVGADQLGDSGVveieSRVSDIPIAFNLEISKFkdygnsDQSGLEQPAGGVVFEVVsNS 444
Cdd:COG4932 316 YTVTETKAPAGYDLDGEAVKVTITAGQTTTVTV----TNGNNEVKTGSVTLTKV------DADDGEAPLAGAEFTLT-DA 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 445 SQQVVGTLTTNVYGFASTKDqpeawfgagkrpagvhgaVPYDRagYTVREVpeTVPEGF-KRAGEWTVGANqiSNGAELQ 523
Cdd:COG4932 385 DGTVVATITTDADGTASFKG------------------LAPGT--YTLTET--KAPEGYtLDSTPITVTVT--DGGTGAI 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 524 YIVDNHALSTHLQIVKRDAqtgasvPLAGFTFQLLDSNHESVSQTC------WYPTHNVMDTFTTDATGTVTLpESLVPG 597
Cdd:COG4932 441 DTITNERKKGSVQVTKVDA------PLAGATFTLTDADGTVVTLTTdadlagATFEADGKVVTTTDASGKYTF-KNLPPG 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 598 TYYVRETSAK---EPYLVGEEIEVNIPADMNLTPVAIASYYDHAATGNIRIVKTDAIDGS---SLAGAVFEIRASSDIVR 671
Cdd:COG4932 514 TYTDAGGSATvitDDTDGTVGDEATGTDPEVTVTGKSTTTTPDVALLTNLGTTEDALTSLaktGDEVGKGLTLTTTTTVD 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 672 PDGSIAALDGETVATITTDETGEARADNLPLGLGTARYEVVETQAPAGFLLDRTTHIVDLTYADQKTPVVEARLNVSDDY 751
Cdd:COG4932 594 TLDTNATEKTETVTVTAQLIGVKTTKLTDTTDPKGGTVEEATTTGGTANTGKTGTDLTDDTTVTSTTNTATSVEDTTDVD 673
|
730
....*....|....*.
gi 2796504302 752 TKVDISKVDASGEQEV 767
Cdd:COG4932 674 NKDAFTGGTEPGGTIV 689
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
652-735 |
4.25e-15 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 71.08 E-value: 4.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 652 DGSSLAGAVFEIRASSDIVrpdgsiaalDGETVATITTDETGEARADNLPLGlgtaRYEVVETQAPAGFLLDRTTHIVDL 731
Cdd:pfam17802 2 TGKPLAGAEFTLYDADGTV---------DGKVVGTLTTDEDGKATFDGLPPG----TYTLKETKAPDGYVLDDTPIEFTV 68
|
....
gi 2796504302 732 TYAD 735
Cdd:pfam17802 69 TEDG 72
|
|
| iso_D2_wall_anc |
NF033902 |
SpaH/EbpB family LPXTG-anchored major pilin; Members of this family are pilin major subunits ... |
640-758 |
1.05e-04 |
|
SpaH/EbpB family LPXTG-anchored major pilin; Members of this family are pilin major subunits whose structure includes an LPXTG motif-containing signal (see TIGR01167) near the C-terminus, for processing by sortases. Most contain a recognizable D2-type fimbrial isopeptide formation domain (see TIGR04226), in which Lys-to-Asn isopeptide bond formation provides additional structural integrity to support adhesion despite shear. For proper members of this subfamily, lengths fall typically in the range of 460 to 640 amino acids in length. Many members of this family contribute to the virulence of certain Gram-positive pathogens, including SpaA, SpaD, and SpaH from Corynebacterium diphtheriae, and EbpB and EbpC from Enterococcus faecalis.
Pssm-ID: 468234 [Multi-domain] Cd Length: 533 Bit Score: 46.29 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 640 TGNIRIVKTDAIDGSS-LAGAVFEIRASSDiVRPDGSIAALDGETVATITTDETGEARADNLPLGLGTARYE-------- 710
Cdd:NF033902 371 FGKLKIKKVDADDTSKkLKGAEFKVYACEA-DAAAACVNAIGINGKTTFTTGADGTVSIDGLHVTDLEDGASvkaaagkd 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2796504302 711 --VVETQAPAGFLLDRTTHIVDLTyADQKTPVVEARLNVSDDYTKVDISK 758
Cdd:NF033902 450 ycLVETKAPAGYVLPPKPVEVTVV-KVTVTAATTADVKNTVVNNKKTVPN 498
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
763-827 |
2.43e-04 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 40.65 E-value: 2.43e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2796504302 763 GEQEVEGAQLTLY----GPDKTEIDSWTSSDK-PHRVEHLAPGTYSLREMMSPRTYDL-AEEITFEIKDTG 827
Cdd:pfam17802 2 TGKPLAGAEFTLYdadgTVDGKVVGTLTTDEDgKATFDGLPPGTYTLKETKAPDGYVLdDTPIEFTVTEDG 72
|
|
| TQXA_dom |
TIGR03934 |
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide ... |
100-132 |
5.32e-04 |
|
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).
Pssm-ID: 274864 [Multi-domain] Cd Length: 42 Bit Score: 38.77 E-value: 5.32e-04
10 20 30
....*....|....*....|....*....|...
gi 2796504302 100 AAIVCHGYPTATSFGGYHLSPDRARAATQLAVW 132
Cdd:TIGR03934 3 LWILANGYPNKSNGELGGLTEEEARAVTQLAIW 35
|
|
| pilus_ancill_1 |
NF033396 |
pilus ancillary protein 1; |
751-836 |
1.20e-03 |
|
pilus ancillary protein 1;
Pssm-ID: 380246 [Multi-domain] Cd Length: 737 Bit Score: 42.95 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 751 YTKVDISKVdasgeqeVEGAQLTLY---GPDKTEIDsWTSSDKPHRVEhLAPGTYSLREMMSPRTYDLAEEITFEIKDtG 827
Cdd:NF033396 272 YAEGDYSKL-------LEGATLKLTqieGSGFQEKI-FQSNSSGETVE-LPNGTYTLTETKSPDGYKIAEPIKFRVKN-G 341
|
....*....
gi 2796504302 828 EVqSVAMKD 836
Cdd:NF033396 342 KV-FIVQKD 349
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ClfA |
COG4932 |
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ... |
79-767 |
6.50e-39 |
|
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443959 [Multi-domain] Cd Length: 689 Bit Score: 155.52 E-value: 6.50e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 79 TKPGGPWLNFDQGWVWLDDEFAAIVCHGYPTATSFGGYHLSPDRARAATQLAVWMLNGTTHVDGTYSYTTAQGKTKSGHF 158
Cdd:COG4932 3 GAKGAGTGVGTVIVEGAGSGSLVAVTTGAVLGLALGSTGGTAGSAAAINSAPATGTATGTSAGATAVIVIAAGLTATPTE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 159 TADNEVVAAARWLHDSAKSGSIKAAPHRARRYLGAVSGGSKRQDMLYVLPAVSVSFQKQSANTV---------------- 222
Cdd:COG4932 83 TASGLGGDATVTTTANVAKVTNGAAANLTVNADGTASNAGTLAKGAETATGNLDGDAGDVTVTAaatdgvndvdgngasv 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 223 --------ITSGNNTYQFTGATFDIFeSASGARVGTIKMDSNGRAQATLLPNTAYYLVETKAPAGYV-----PRHDRIAF 289
Cdd:COG4932 163 tdsvtlkkVDDGDTGKPLPGATFTLY-DSDGTLVKTVTTDADGKYTFTDLPPGTYTLTETKAPEGYVldtkdPTGATITV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 290 TTGNDGGR---VAIDEQPGTINLRIVKLDAATnagpqvGSSLAGAEFTCVSQS--TPGWAQILTTDESGRATLADVPLGT 364
Cdd:COG4932 242 TVNAGGTVtvtLKNTPKYTKGSVTVTKTDADT------GEPLAGATFTLTDADgnTVVTTTVTVTDADGSYTFTDLPPGT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 365 FTIYESKTPEGYLPSNDSWTYTVGADQLGDSGVveieSRVSDIPIAFNLEISKFkdygnsDQSGLEQPAGGVVFEVVsNS 444
Cdd:COG4932 316 YTVTETKAPAGYDLDGEAVKVTITAGQTTTVTV----TNGNNEVKTGSVTLTKV------DADDGEAPLAGAEFTLT-DA 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 445 SQQVVGTLTTNVYGFASTKDqpeawfgagkrpagvhgaVPYDRagYTVREVpeTVPEGF-KRAGEWTVGANqiSNGAELQ 523
Cdd:COG4932 385 DGTVVATITTDADGTASFKG------------------LAPGT--YTLTET--KAPEGYtLDSTPITVTVT--DGGTGAI 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 524 YIVDNHALSTHLQIVKRDAqtgasvPLAGFTFQLLDSNHESVSQTC------WYPTHNVMDTFTTDATGTVTLpESLVPG 597
Cdd:COG4932 441 DTITNERKKGSVQVTKVDA------PLAGATFTLTDADGTVVTLTTdadlagATFEADGKVVTTTDASGKYTF-KNLPPG 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 598 TYYVRETSAK---EPYLVGEEIEVNIPADMNLTPVAIASYYDHAATGNIRIVKTDAIDGS---SLAGAVFEIRASSDIVR 671
Cdd:COG4932 514 TYTDAGGSATvitDDTDGTVGDEATGTDPEVTVTGKSTTTTPDVALLTNLGTTEDALTSLaktGDEVGKGLTLTTTTTVD 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 672 PDGSIAALDGETVATITTDETGEARADNLPLGLGTARYEVVETQAPAGFLLDRTTHIVDLTYADQKTPVVEARLNVSDDY 751
Cdd:COG4932 594 TLDTNATEKTETVTVTAQLIGVKTTKLTDTTDPKGGTVEEATTTGGTANTGKTGTDLTDDTTVTSTTNTATSVEDTTDVD 673
|
730
....*....|....*.
gi 2796504302 752 TKVDISKVDASGEQEV 767
Cdd:COG4932 674 NKDAFTGGTEPGGTIV 689
|
|
| ClfA |
COG4932 |
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ... |
382-877 |
6.24e-32 |
|
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443959 [Multi-domain] Cd Length: 689 Bit Score: 133.94 E-value: 6.24e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 382 SWTYTVGADQLGDSGVVEIESRVSDIPIAFNLEISKFKDYGNSDQSGLEQPAGGVVFEVVSNSSQQVVGTLTTNVYGFAS 461
Cdd:COG4932 6 GAGTGVGTVIVEGAGSGSLVAVTTGAVLGLALGSTGGTAGSAAAINSAPATGTATGTSAGATAVIVIAAGLTATPTETAS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 462 TKDQPEAWFGAGKRPAGVHGAVPYDRAGYTVREVPETVPEGFKRAGEWTVGANQISNGAELQY-------IVDNHALSTH 534
Cdd:COG4932 86 GLGGDATVTTTANVAKVTNGAAANLTVNADGTASNAGTLAKGAETATGNLDGDAGDVTVTAAAtdgvndvDGNGASVTDS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 535 LQIVKRDAqTGASVPLAGFTFQLLDSNHESVSqtcwypthnvmdTFTTDATGTVTLPEsLVPGTYYVRETSAKEPYLVGE 614
Cdd:COG4932 166 VTLKKVDD-GDTGKPLPGATFTLYDSDGTLVK------------TVTTDADGKYTFTD-LPPGTYTLTETKAPEGYVLDT 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 615 EIEVNIPADMNLTPVAIASYY----DHAATGNIRIVKTDAIDGSSLAGAVFEIRASSDIVRPDGSIAaldgetvatiTTD 690
Cdd:COG4932 232 KDPTGATITVTVNAGGTVTVTlkntPKYTKGSVTVTKTDADTGEPLAGATFTLTDADGNTVVTTTVT----------VTD 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 691 ETGEARADNLPLGlgtaRYEVVETQAPAGFLLDRTTHIVDLTyADQKTPVVEARLNVSDDYTKVDISKVDAS-GEQEVEG 769
Cdd:COG4932 302 ADGSYTFTDLPPG----TYTVTETKAPAGYDLDGEAVKVTIT-AGQTTTVTVTNGNNEVKTGSVTLTKVDADdGEAPLAG 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 770 AQLTLYGPDKTEIDSWTS-SDKPHRVEHLAPGTYSLREMMSPRTYDL-AEEITFEIKDTGEVQSVAMKDAPIEIKGQVDK 847
Cdd:COG4932 377 AEFTLTDADGTVVATITTdADGTASFKGLAPGTYTLTETKAPEGYTLdSTPITVTVTDGGTGAIDTITNERKKGSVQVTK 456
|
490 500 510
....*....|....*....|....*....|
gi 2796504302 848 RQELVQPIEKGLLANGDGKNRAATQTNTDG 877
Cdd:COG4932 457 VDAPLAGATFTLTDADGTVVTLTTDADLAG 486
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
652-735 |
4.25e-15 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 71.08 E-value: 4.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 652 DGSSLAGAVFEIRASSDIVrpdgsiaalDGETVATITTDETGEARADNLPLGlgtaRYEVVETQAPAGFLLDRTTHIVDL 731
Cdd:pfam17802 2 TGKPLAGAEFTLYDADGTV---------DGKVVGTLTTDEDGKATFDGLPPG----TYTLKETKAPDGYVLDDTPIEFTV 68
|
....
gi 2796504302 732 TYAD 735
Cdd:pfam17802 69 TEDG 72
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
325-391 |
1.15e-10 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 58.37 E-value: 1.15e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 325 GSSLAGAEFT---CVSQSTPGWAQILTTDESGRATLADVPLGTFTIYESKTPEGYLPSNDSWTYTVGADQ 391
Cdd:pfam17802 3 GKPLAGAEFTlydADGTVDGKVVGTLTTDEDGKATFDGLPPGTYTLKETKAPDGYVLDDTPIEFTVTEDG 72
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
549-623 |
8.99e-10 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 56.05 E-value: 8.99e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2796504302 549 PLAGFTFQLLDSNHEsvsqtcwyPTHNVMDTFTTDATGTVTLpESLVPGTYYVRETSAKEPYLV-GEEIEVNIPAD 623
Cdd:pfam17802 5 PLAGAEFTLYDADGT--------VDGKVVGTLTTDEDGKATF-DGLPPGTYTLKETKAPDGYVLdDTPIEFTVTED 71
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
234-295 |
4.12e-08 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 51.05 E-value: 4.12e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2796504302 234 GATFDIF---ESASGARVGTIKMDSNGRAQATLLPNTAYYLVETKAPAGYVPRHDRIAFTTGNDG 295
Cdd:pfam17802 8 GAEFTLYdadGTVDGKVVGTLTTDEDGKATFDGLPPGTYTLKETKAPDGYVLDDTPIEFTVTEDG 72
|
|
| TED |
pfam08341 |
Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface ... |
67-177 |
2.27e-07 |
|
Thioester domain; This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.
Pssm-ID: 462437 [Multi-domain] Cd Length: 105 Bit Score: 50.31 E-value: 2.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 67 IAYCMNQERPGPTKPGGP--WLNFDQGWVWLDDEFAAIVCHGYP--TATSFGGYHLSPDRARAATQLAVWMLngtthVDG 142
Cdd:pfam08341 1 PAYCIEPGKGFPSGGDGTasSETRLTLYKDNADKINWILYNGYPnkSGLSEELGGLTDDDAYAATQAAIWHF-----TDG 75
|
90 100 110
....*....|....*....|....*....|....*
gi 2796504302 143 TYSYTTAQGKTksghfTADNEVVAAARWLHDSAKS 177
Cdd:pfam08341 76 VDGASDGDGGT-----ERDDDVKKLYDYLIGNANK 105
|
|
| iso_D2_wall_anc |
NF033902 |
SpaH/EbpB family LPXTG-anchored major pilin; Members of this family are pilin major subunits ... |
640-758 |
1.05e-04 |
|
SpaH/EbpB family LPXTG-anchored major pilin; Members of this family are pilin major subunits whose structure includes an LPXTG motif-containing signal (see TIGR01167) near the C-terminus, for processing by sortases. Most contain a recognizable D2-type fimbrial isopeptide formation domain (see TIGR04226), in which Lys-to-Asn isopeptide bond formation provides additional structural integrity to support adhesion despite shear. For proper members of this subfamily, lengths fall typically in the range of 460 to 640 amino acids in length. Many members of this family contribute to the virulence of certain Gram-positive pathogens, including SpaA, SpaD, and SpaH from Corynebacterium diphtheriae, and EbpB and EbpC from Enterococcus faecalis.
Pssm-ID: 468234 [Multi-domain] Cd Length: 533 Bit Score: 46.29 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 640 TGNIRIVKTDAIDGSS-LAGAVFEIRASSDiVRPDGSIAALDGETVATITTDETGEARADNLPLGLGTARYE-------- 710
Cdd:NF033902 371 FGKLKIKKVDADDTSKkLKGAEFKVYACEA-DAAAACVNAIGINGKTTFTTGADGTVSIDGLHVTDLEDGASvkaaagkd 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2796504302 711 --VVETQAPAGFLLDRTTHIVDLTyADQKTPVVEARLNVSDDYTKVDISK 758
Cdd:NF033902 450 ycLVETKAPAGYVLPPKPVEVTVV-KVTVTAATTADVKNTVVNNKKTVPN 498
|
|
| SpaA |
pfam17802 |
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety ... |
763-827 |
2.43e-04 |
|
Prealbumin-like fold domain; This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.
Pssm-ID: 465513 [Multi-domain] Cd Length: 72 Bit Score: 40.65 E-value: 2.43e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2796504302 763 GEQEVEGAQLTLY----GPDKTEIDSWTSSDK-PHRVEHLAPGTYSLREMMSPRTYDL-AEEITFEIKDTG 827
Cdd:pfam17802 2 TGKPLAGAEFTLYdadgTVDGKVVGTLTTDEDgKATFDGLPPGTYTLKETKAPDGYVLdDTPIEFTVTEDG 72
|
|
| TQXA_dom |
TIGR03934 |
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide ... |
100-132 |
5.32e-04 |
|
TQXA domain; This model describes a domain of about 40 residues with an invariant TQ dipeptide in an almost invariant TQxA[VI]W motif. This domain occurs in surface-expressed proteins of Gram-positive bacteria, many of which are anchored by LPXTG-containing sortase target domains. Numerous members of this family have domains pfam05738 (Cna protein B-type domain) and pfam08341 (fibronectin-binding protein signal sequence).
Pssm-ID: 274864 [Multi-domain] Cd Length: 42 Bit Score: 38.77 E-value: 5.32e-04
10 20 30
....*....|....*....|....*....|...
gi 2796504302 100 AAIVCHGYPTATSFGGYHLSPDRARAATQLAVW 132
Cdd:TIGR03934 3 LWILANGYPNKSNGELGGLTEEEARAVTQLAIW 35
|
|
| pilus_ancill_1 |
NF033396 |
pilus ancillary protein 1; |
751-836 |
1.20e-03 |
|
pilus ancillary protein 1;
Pssm-ID: 380246 [Multi-domain] Cd Length: 737 Bit Score: 42.95 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796504302 751 YTKVDISKVdasgeqeVEGAQLTLY---GPDKTEIDsWTSSDKPHRVEhLAPGTYSLREMMSPRTYDLAEEITFEIKDtG 827
Cdd:NF033396 272 YAEGDYSKL-------LEGATLKLTqieGSGFQEKI-FQSNSSGETVE-LPNGTYTLTETKSPDGYKIAEPIKFRVKN-G 341
|
....*....
gi 2796504302 828 EVqSVAMKD 836
Cdd:NF033396 342 KV-FIVQKD 349
|
|
| |
