NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|568922752|ref|XP_006501524|]
View 

FRAS1-related extracellular matrix protein 2 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 1.97e-122

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


:

Pssm-ID: 466034  Cd Length: 202  Bit Score: 382.83  E-value: 1.97e-122
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752    65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 568922752   225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 1.07e-33

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.18  E-value: 1.07e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 568922752  1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 2.03e-33

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 125.41  E-value: 2.03e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 568922752  1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 1.59e-32

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.71  E-value: 1.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 568922752  1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 7.59e-32

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 120.79  E-value: 7.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 568922752   494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.70e-26

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 105.38  E-value: 1.70e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 568922752  1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 1.23e-25

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 103.07  E-value: 1.23e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 568922752   616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 4.06e-23

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 95.75  E-value: 4.06e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752  1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.97e-21

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 90.35  E-value: 2.97e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 568922752  1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
Cadherin_3 super family cl28802
Cadherin-like;
804-909 4.30e-17

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 78.80  E-value: 4.30e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 568922752   883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 super family cl28802
Cadherin-like;
672-797 8.26e-14

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.17  E-value: 8.26e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 568922752   752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
Cadherin_3 super family cl28802
Cadherin-like;
912-1026 1.26e-12

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.09  E-value: 1.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752   990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Cadherin_3 super family cl28802
Cadherin-like;
329-389 1.11e-09

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 57.61  E-value: 1.11e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568922752   329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
 
Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 1.97e-122

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 382.83  E-value: 1.97e-122
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752    65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 568922752   225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 1.07e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.18  E-value: 1.07e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 568922752  1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 2.03e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 125.41  E-value: 2.03e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 568922752  1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 1.59e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.71  E-value: 1.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 568922752  1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 7.59e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 120.79  E-value: 7.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 568922752   494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.70e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 105.38  E-value: 1.70e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 568922752  1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 1.23e-25

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 103.07  E-value: 1.23e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 568922752   616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 4.06e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 95.75  E-value: 4.06e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752  1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.97e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 90.35  E-value: 2.97e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 568922752  1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
804-909 4.30e-17

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 78.80  E-value: 4.30e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 568922752   883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
672-797 8.26e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.17  E-value: 8.26e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 568922752   752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
912-1026 1.26e-12

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.09  E-value: 1.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752   990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
329-389 1.11e-09

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 57.61  E-value: 1.11e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568922752   329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
 
Name Accession Description Interval E-value
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
65-277 1.97e-122

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 382.83  E-value: 1.97e-122
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752    65 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRV 144
Cdd:pfam19309    1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   145 RLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYG 224
Cdd:pfam19309   81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 568922752   225 ELLHYPQVqggagdrgtskTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVV 277
Cdd:pfam19309  161 RLVNATGA-----------PLMVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
Cadherin_3 pfam16184
Cadherin-like;
1505-1612 1.07e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 126.18  E-value: 1.07e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1505 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1581
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 568922752  1582 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1612
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1275-1390 2.03e-33

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 125.41  E-value: 2.03e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1275 HSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQRQKPLGafENIT 1354
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPG--LPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 568922752  1355 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1390
Cdd:pfam16184   79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1395-1503 1.59e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 122.71  E-value: 1.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1395 IDRYFYVTIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQ 1473
Cdd:pfam16184    3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
                           90       100       110
                   ....*....|....*....|....*....|
gi 568922752  1474 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1503
Cdd:pfam16184   83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
415-532 7.59e-32

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 120.79  E-value: 7.59e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   415 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpigsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSs 493
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPG- 74
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 568922752   494 dSAPKTFTVAELAAGQVVYQHDDKDgSLSDNLVLRMSDG 532
Cdd:pfam16184   75 -LPVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1163-1273 1.70e-26

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 105.38  E-value: 1.70e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1163 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLiNGTVLVESF 1241
Cdd:pfam16184    2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
                           90       100       110
                   ....*....|....*....|....*....|..
gi 568922752  1242 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1273
Cdd:pfam16184   81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
536-665 1.23e-25

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 103.07  E-value: 1.23e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   536 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSlGHLLLRqrhvpqeeq 615
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSH-GHLALK--------- 70
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 568922752   616 glwqkqgSFYERTVTEWRQQDITEGKLFYRHSGphsPGPVMDQFMFRVQD 665
Cdd:pfam16184   71 -------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
1042-1159 4.06e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 95.75  E-value: 4.06e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1042 VTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENispapgseKSRAGVA 1121
Cdd:pfam16184    5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752  1122 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1159
Cdd:pfam16184   77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1630-1742 2.97e-21

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 90.35  E-value: 2.97e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752  1630 PQVMKIQVLPVDNSVPQIVVNKGastLRTLATGHlgFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1709
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|...
gi 568922752  1710 QFTQADIDDMKICYVlRERANATSDMFHFIVED 1742
Cdd:pfam16184   79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
804-909 4.30e-17

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 78.80  E-value: 4.30e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   804 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLE 882
Cdd:pfam16184    4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
                           90       100
                   ....*....|....*....|....*..
gi 568922752   883 DIKHGRISYWNSGDESLTDSCSLEVSD 909
Cdd:pfam16184   84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
672-797 8.26e-14

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 69.17  E-value: 8.26e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   672 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPtdtdeNHspaplGTLV 751
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 568922752   752 FTDNPSVVVSHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 797
Cdd:pfam16184   69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
912-1026 1.26e-12

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 66.09  E-value: 1.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568922752   912 HVVPITLRVNVRPGDREGPMSVLPAGtlesyLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAP-- 989
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 568922752   990 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1026
Cdd:pfam16184   76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
Cadherin_3 pfam16184
Cadherin-like;
329-389 1.11e-09

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 57.61  E-value: 1.11e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568922752   329 TALTPDMLAAEDAESDPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 389
Cdd:pfam16184   35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
Cadherin_4 pfam17803
Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains ...
544-605 8.37e-03

Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.


Pssm-ID: 465514 [Multi-domain]  Cd Length: 71  Bit Score: 36.78  E-value: 8.37e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568922752   544 ITLVPVDDqPPVLNANTGlTVAEGETVPIPP-LTLSATDIDSDDsqLVFVLLPPFSSLGHLLL 605
Cdd:pfam17803    5 ITVTGVND-APVAVDDTA-TVDEDTPVTITGnVLANDTDVDGDT--LTVTSVTGAPAYGTLTL 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH