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Conserved domains on  [gi|767955216|ref|XP_011516311|]
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excitatory amino acid transporter 3 isoform X4 [Homo sapiens]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
11-448 4.74e-109

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 329.77  E-value: 4.74e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  11 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 89
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  90 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 169
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 170 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 249
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 250 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 329
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 330 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 409
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357
                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955216 410 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 448
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
11-448 4.74e-109

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 329.77  E-value: 4.74e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  11 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 89
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  90 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 169
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 170 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 249
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 250 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 329
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 330 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 409
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357
                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955216 410 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 448
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
31-445 1.28e-105

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 320.62  E-value: 1.28e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216   31 YFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIAR 109
Cdd:pfam00375  25 WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIAASL 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  110 TGStpEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkppsdpemnmteesftavmttaisknktkeykivgmysdg 189
Cdd:pfam00375 105 KEA--KAAEAPSLLDFILNIIPSNIFEALAEG------------------------------------------------ 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  190 iNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATV 269
Cdd:pfam00375 135 -NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILSSLAKFLLVV 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  270 LTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 349
Cdd:pfam00375 213 YLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDG 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  350 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTM 429
Cdd:pfam00375 293 TAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTA 372
                         410
                  ....*....|....*.
gi 767955216  430 VNVLGDAFGTGIVEKL 445
Cdd:pfam00375 373 VNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
68-444 1.02e-33

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 132.33  E-value: 1.02e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  68 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVtqkvgeiartGSTPEVSTVDAmldlirnmfpenlvqACFQQYKTKRE 147
Cdd:PRK01663  71 GRVGGKALLYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA---------------KAVAQYAAQAH 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 148 EvkppsdpemnmteESFTAVMTTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 227
Cdd:PRK01663 126 E-------------QGTVDFLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVL 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 228 MKIVQIIMCYMPLGILFLIA--------GKIIevedweifrKLGLYMATVLTGLAIHSIVILPLIyfivVRKNPF---RF 296
Cdd:PRK01663 186 FGIVNMIMKLAPIGAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAI----ARLTGFsifKF 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 297 AMGMAQALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 376
Cdd:PRK01663 253 IRYIKEELLIVLGTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQIT 331
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767955216 377 ISITATSASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 444
Cdd:PRK01663 332 LLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
11-448 4.74e-109

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 329.77  E-value: 4.74e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  11 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 89
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  90 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 169
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 170 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 249
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 250 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 329
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 330 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 409
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357
                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955216 410 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 448
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
31-445 1.28e-105

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 320.62  E-value: 1.28e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216   31 YFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIAR 109
Cdd:pfam00375  25 WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIAASL 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  110 TGStpEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkppsdpemnmteesftavmttaisknktkeykivgmysdg 189
Cdd:pfam00375 105 KEA--KAAEAPSLLDFILNIIPSNIFEALAEG------------------------------------------------ 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  190 iNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATV 269
Cdd:pfam00375 135 -NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILSSLAKFLLVV 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  270 LTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 349
Cdd:pfam00375 213 YLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDG 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  350 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTM 429
Cdd:pfam00375 293 TAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTA 372
                         410
                  ....*....|....*.
gi 767955216  430 VNVLGDAFGTGIVEKL 445
Cdd:pfam00375 373 VNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
68-444 1.02e-33

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 132.33  E-value: 1.02e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  68 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVtqkvgeiartGSTPEVSTVDAmldlirnmfpenlvqACFQQYKTKRE 147
Cdd:PRK01663  71 GRVGGKALLYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA---------------KAVAQYAAQAH 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 148 EvkppsdpemnmteESFTAVMTTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 227
Cdd:PRK01663 126 E-------------QGTVDFLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVL 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 228 MKIVQIIMCYMPLGILFLIA--------GKIIevedweifrKLGLYMATVLTGLAIHSIVILPLIyfivVRKNPF---RF 296
Cdd:PRK01663 186 FGIVNMIMKLAPIGAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAI----ARLTGFsifKF 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 297 AMGMAQALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 376
Cdd:PRK01663 253 IRYIKEELLIVLGTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQIT 331
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767955216 377 ISITATSASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 444
Cdd:PRK01663 332 LLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
11-444 1.78e-33

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 131.81  E-value: 1.78e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  11 GITTGVLVREHSNLSTLEKFYFAFP-GEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVIL 88
Cdd:PRK11283  19 GILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTVAIIL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  89 GIVLVVSIKPGVTQKVGEIArtgstpevsTVDamldlirnmfpenlvqacFQQYKTKREEVKPPSdpemnmteESFTAVM 168
Cdd:PRK11283  99 GITLANVFQPGAGIDMSQLA---------TVD------------------ISKYQSTTEEVQSHS--------HGLMGTI 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 169 TTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEK-GQILVDFFNALSDATMKIVQIIMCYMPLGILFLIA 247
Cdd:PRK11283 144 LSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIA 216
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 248 gkiIEVEDWEIFRKLGLYMATVLTGLAI--HSIVILPLIYFIVvRKNPFRFAMGMAQALLTALMISSSSATLPvtfRCAE 325
Cdd:PRK11283 217 ---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP---RIIE 289
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 326 --ENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVL 403
Cdd:PRK11283 290 kmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATL 369
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 767955216 404 SAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 444
Cdd:PRK11283 370 GSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
68-442 5.86e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 127.09  E-value: 5.86e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216  68 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQkvgeiartgstpevstvdamldlirNMFPENLVQACFQQYKTKRE 147
Cdd:PRK13027  70 GRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGM-------------------------NIDLRSLDAASLAGYAKNAQ 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 148 EVKPPSDPEMNMTEESFtavmttaisknktkeykiVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 227
Cdd:PRK13027 125 SLKGTAGFLLKLIPTTA------------------VDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVL 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 228 MKIVQIIMCYMPLGILFLIAgkiIEVEDWEI--FRKLGLYMATVLTGLAIHSIVILPLiyfiVVRKNPFR---FAMGMAQ 302
Cdd:PRK13027 186 FRIMGFIIKLAPLGVLGAIA---FTTGKYGVgsLKQLGMLVAVFYLTCFVFVVVVLGA----VMRLAGFSvfkLIRYLRE 258
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 303 ALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITAT 382
Cdd:PRK13027 259 ELLIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSL 337
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767955216 383 SASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIV 442
Cdd:PRK13027 338 VTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
191-449 1.19e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 65.84  E-value: 1.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 191 NVLGLIVFCLVFGLVigkMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAgKIIEVEDWEIFRKLGLYMATVL 270
Cdd:PRK14695  60 NYIGILSWAVIFGIA---MREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLANYGILLVLLV 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 271 TGLAIHSIVILPLIYFIVVRKNPFRFAMG-MAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDG 349
Cdd:PRK14695 136 TTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRVSGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMAG 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 350 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLL----DR 425
Cdd:PRK14695 215 VAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDS 294
                        250       260
                 ....*....|....*....|....
gi 767955216 426 FRTMVNVLGDAFGTGIVEKLSKKE 449
Cdd:PRK14695 295 CETALNSSTDVLFTAVAEYAATRK 318
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
218-391 9.84e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 63.34  E-value: 9.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 218 DFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFA 297
Cdd:PRK13628 170 NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAE-TGFSALAGYAQLLAVLVGCMLFVALVVNPLIVFWKIRRNPYPLV 248
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 298 MG-MAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDGTALYEAV---AAVFIaqlndldLGI-- 371
Cdd:PRK13628 249 FTcLRESGVTAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVltlAAVHT-------LGIpv 320
                        170       180
                 ....*....|....*....|..
gi 767955216 372 --GQIITISITATSASIGAAGV 391
Cdd:PRK13628 321 dlPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
218-392 1.83e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 62.88  E-value: 1.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 218 DFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFA 297
Cdd:COG3633  169 TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT-GFSALLGYAHLLAVLVGCMLFVALVVNPLIVFLKIRRNPYPLV 247
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955216 298 -MGMAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 376
Cdd:COG3633  248 fTCLRESGITAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALL 326
                        170
                 ....*....|....*.
gi 767955216 377 ISITATSASIGAAGVP 392
Cdd:COG3633  327 LSVVAAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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