uncharacterized protein LOC110347653, partial [Heterocephalus glaber]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| MobM_relaxase super family | cl03088 | relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a ... |
1-70 | 3.01e-23 | ||
relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a site-specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre (plasmid recombination enzyme), also known as Mob (conjugative mobilization). The best characterized member of this family is encoded by the streptococcal plasmid pMV158 that recognizes the plasmid origin of transfer. MobM converts supercoiled plasmid DNA into relaxed DNA by cleaving a phosphodiester bond of a specific dinucleotide and remains bound to the 5'-end of the nick site. The actual alignment was detected with superfamily member pfam01076: Pssm-ID: 470731 Cd Length: 195 Bit Score: 93.93 E-value: 3.01e-23
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| Name | Accession | Description | Interval | E-value | ||
| Mob_Pre | pfam01076 | Plasmid recombination enzyme; With some plasmids, recombination can occur in a site specific ... |
1-70 | 3.01e-23 | ||
Plasmid recombination enzyme; With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilization). This family is also known as Mob-V. One of the family members, MobM, is encoded by a promiscuous plasmid actively involved in the spread of antibiotic resistance. Homologs of MobM are found in many plasmids and other mobile genetic elements of pathogenic bacteria, including S. aureus. MobM is a metal-dependent nuclease that uses histidine nitrogen for the nucleophilic attack on the scissile phosphate. Furthermore, in contrast to other DNA-processing enzymes, MobM is a histidine relaxase, a DNA-breaking and -joining enzyme, that operates through a phosphorus-nitrogen protein-DNA adduct for cell-to-cell DNA transfer. Mutational analysis indicate that the H(N/D)(Q/E)R N-terminal motif of MobM plays a crucial role in the cleavage and generation of stable DNA-protein adducts. Pssm-ID: 395854 Cd Length: 195 Bit Score: 93.93 E-value: 3.01e-23
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| MobV | NF041497 | MobV family relaxase; |
1-62 | 3.64e-23 | ||
MobV family relaxase; Pssm-ID: 469385 Cd Length: 187 Bit Score: 93.40 E-value: 3.64e-23
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| MobM_relaxase | cd17242 | relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a ... |
1-77 | 1.06e-18 | ||
relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a site-specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre (plasmid recombination enzyme), also known as Mob (conjugative mobilization). The best characterized member of this family is encoded by the streptococcal plasmid pMV158 that recognizes the plasmid origin of transfer. MobM converts supercoiled plasmid DNA into relaxed DNA by cleaving a phosphodiester bond of a specific dinucleotide and remains bound to the 5'-end of the nick site. Pssm-ID: 410988 Cd Length: 196 Bit Score: 81.54 E-value: 1.06e-18
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| Name | Accession | Description | Interval | E-value | ||
| Mob_Pre | pfam01076 | Plasmid recombination enzyme; With some plasmids, recombination can occur in a site specific ... |
1-70 | 3.01e-23 | ||
Plasmid recombination enzyme; With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilization). This family is also known as Mob-V. One of the family members, MobM, is encoded by a promiscuous plasmid actively involved in the spread of antibiotic resistance. Homologs of MobM are found in many plasmids and other mobile genetic elements of pathogenic bacteria, including S. aureus. MobM is a metal-dependent nuclease that uses histidine nitrogen for the nucleophilic attack on the scissile phosphate. Furthermore, in contrast to other DNA-processing enzymes, MobM is a histidine relaxase, a DNA-breaking and -joining enzyme, that operates through a phosphorus-nitrogen protein-DNA adduct for cell-to-cell DNA transfer. Mutational analysis indicate that the H(N/D)(Q/E)R N-terminal motif of MobM plays a crucial role in the cleavage and generation of stable DNA-protein adducts. Pssm-ID: 395854 Cd Length: 195 Bit Score: 93.93 E-value: 3.01e-23
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| MobV | NF041497 | MobV family relaxase; |
1-62 | 3.64e-23 | ||
MobV family relaxase; Pssm-ID: 469385 Cd Length: 187 Bit Score: 93.40 E-value: 3.64e-23
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| MobM_relaxase | cd17242 | relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a ... |
1-77 | 1.06e-18 | ||
relaxase domain of MobM and similar proteins; With some plasmids, recombination can occur in a site-specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre (plasmid recombination enzyme), also known as Mob (conjugative mobilization). The best characterized member of this family is encoded by the streptococcal plasmid pMV158 that recognizes the plasmid origin of transfer. MobM converts supercoiled plasmid DNA into relaxed DNA by cleaving a phosphodiester bond of a specific dinucleotide and remains bound to the 5'-end of the nick site. Pssm-ID: 410988 Cd Length: 196 Bit Score: 81.54 E-value: 1.06e-18
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