NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1338812033|ref|XP_023648289|]
View 

nuclear mitotic apparatus protein 1 isoform X2 [Paramormyrops kingsleyae]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 5-153 2.28e-63

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 212.43  E-value: 2.28e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033    5 RKKEEALLNWINSLHLDSPIDHIFLLQDGVILVKLIHKLKKQEIGvDAVLELPLQGRLDFISAFLQKDCRYKADRGTIVS 84
Cdd:cd22224      1 NTKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEE-EQILDLSVEERLEFISSFLEGDCRFNSSQGTLVS 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033   85 WDNIVLGKNLDVELSKVVVLLLYHSLMNGLLGLDRLGYDIELELADVLRFVLNNEDSLYLSDNLEKILK 153
Cdd:cd22224     80 WQKILQGENLELELAKVLLLLLYHSMMNNNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 454-1293 3.74e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.30  E-value: 3.74e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  454 ARLEELVSELNKMLtvQRGEREAlEQALREQRvsLEAQIEALtadiaslteavqQRELAVTNFSQKVDvERKRVEKLTEE 533
Cdd:TIGR02168  189 DRLEDILNELERQL--KSLERQA-EKAERYKE--LKAELREL------------ELALLVLRLEELRE-ELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  534 MEKQERFAQKTIQELHERVDHLGS---VLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQ 610
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLevsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  611 EKEEVACKLNQQIVLLEEQQSVEWSL---LSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELdseaQRASHQEEVESLK 687
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLeaeLEELEAELEELESRLEELEEQLETLRSKVAQLEL----QIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  688 RKLHEAEsilgvyegklADHQKIVEEHIALRDELSAAAecakglRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKT 767
Cdd:TIGR02168  407 ARLERLE----------DRRERLQQEIEELLKKLEEAE------LKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  768 QNMSVEMQHLGQQLSKVQQEKmrvdasmaKLIEEGREVERGLTAArdqafltIKEREAETSKLRSEAEALSSKVILAEE- 846
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARL--------DSLERLQENLEGFSEG-------VKALLKNQSGLSGILGVLSELISVDEGy 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  847 AKAIELAkkddemqvLSKEMKQIQMElgTVKKAKDDMELDLQSSIEKRQeQLLVLRFQMNELEESANQKETEIEVLQTKL 926
Cdd:TIGR02168  536 EAAIEAA--------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVT-FLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  927 SNKDEELKAFclhEKV------------EREELQRQLKQeedrcLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIH 994
Cdd:TIGR02168  605 KDLVKFDPKL---RKAlsyllggvlvvdDLDNALELAKK-----LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  995 SGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKvsddal 1074
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA------ 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1075 iHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLgtaSALASEKDSQLELL 1154
Cdd:TIGR02168  751 -QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1155 HAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLhaeLKERDSLRIQAAEMEARHKELEESI 1234
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEEL 903

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKE------------RDGLRIQAAEMEARHKELEESIAQLQARL 1293
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGlevridnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRL 974
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 213-539 2.58e-14

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.58e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  213 RKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQC 292
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  293 QELKTNKTQM----ERKIDDLTEENGILSVQMREIFSRLSSAE-AAVQKLSAEQESSQVEWESKRGLLESELGQALSQKE 367
Cdd:TIGR02169  750 EQEIENVKSElkelEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  368 YLNEQIQILQGKISILED-ELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEvek 446
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEqIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE--- 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  447 tKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVS---------LEAQIEALTADIASLTE----AVQQRELAV 513
Cdd:TIGR02169  907 -ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIRALEPvnmlAIQEYEEVL 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1338812033  514 TNFS------QKVDVERKRVEKLTEEMEKQER 539
Cdd:TIGR02169  986 KRLDelkekrAKLEEERKAILERIEEYEKKKR 1017
NuMA_LGNBD super family cl41700
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1796-1844 1.84e-11

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


The actual alignment was detected with superfamily member cd22298:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 61.07  E-value: 1.84e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1796 LLSLPGYRRSTTHS------HVPPRNINTYGVGA-ENEPDVTDDWKRIVELQARNK 1844
Cdd:cd22298      1 LLSLPGYRPSTRSStrrsqsSSATGGRSTFYMGTcQDEPEHLDDWNRIAELQQRNR 56
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1084-1600 6.30e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1084 LKNEVTSLQELAEKLKGELEELKREHEN-----LRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAEL 1158
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 KERDSlriqaaeMEARH-KELEESIAQLQARLGTASALASEK----DSQLELLHAELKER---------------DSLRI 1218
Cdd:pfam15921  309 RNQNS-------MYMRQlSDLESTVSQLRSELREAKRMYEDKieelEKQLVLANSELTEArterdqfsqesgnldDQLQK 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKEL---EESIAQLQAQLGTASVLASEKDSQLESLHAELKERDGLrIQAAEMEARhKELEESIAQLQAR--- 1292
Cdd:pfam15921  382 LLADLHKREKELsleKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL-LKAMKSECQ-GQMERQMAAIQGKnes 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1293 LGTASALASGKQSELDLLHKEVREREKLRI--------------------RAVEVEEAQHKELEERV----TEASTLASE 1348
Cdd:pfam15921  460 LEKVSSLTAQLESTKEMLRKVVEELTAKKMtlessertvsdltaslqekeRAIEATNAEITKLRSRVdlklQELQHLKNE 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1349 R------KSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSL----AAVQKRVNE-------------KLNED 1405
Cdd:pfam15921  540 GdhlrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqvekAQLEKEINDrrlelqefkilkdKKDAK 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1406 IRRLDVvRQESMERDALRIRAIEAEDLKR-KEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQ----TLLSMK 1480
Cdd:pfam15921  620 IRELEA-RVSDLELEKVKLVNAGSERLRAvKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEemetTTNKLK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1481 ESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQL 1560
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL 778

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1338812033 1561 LEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKL 1600
Cdd:pfam15921  779 STVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASL 818
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 5-153 2.28e-63

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 212.43  E-value: 2.28e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033    5 RKKEEALLNWINSLHLDSPIDHIFLLQDGVILVKLIHKLKKQEIGvDAVLELPLQGRLDFISAFLQKDCRYKADRGTIVS 84
Cdd:cd22224      1 NTKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEE-EQILDLSVEERLEFISSFLEGDCRFNSSQGTLVS 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033   85 WDNIVLGKNLDVELSKVVVLLLYHSLMNGLLGLDRLGYDIELELADVLRFVLNNEDSLYLSDNLEKILK 153
Cdd:cd22224     80 WQKILQGENLELELAKVLLLLLYHSMMNNNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 454-1293 3.74e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.30  E-value: 3.74e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  454 ARLEELVSELNKMLtvQRGEREAlEQALREQRvsLEAQIEALtadiaslteavqQRELAVTNFSQKVDvERKRVEKLTEE 533
Cdd:TIGR02168  189 DRLEDILNELERQL--KSLERQA-EKAERYKE--LKAELREL------------ELALLVLRLEELRE-ELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  534 MEKQERFAQKTIQELHERVDHLGS---VLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQ 610
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLevsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  611 EKEEVACKLNQQIVLLEEQQSVEWSL---LSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELdseaQRASHQEEVESLK 687
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLeaeLEELEAELEELESRLEELEEQLETLRSKVAQLEL----QIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  688 RKLHEAEsilgvyegklADHQKIVEEHIALRDELSAAAecakglRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKT 767
Cdd:TIGR02168  407 ARLERLE----------DRRERLQQEIEELLKKLEEAE------LKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  768 QNMSVEMQHLGQQLSKVQQEKmrvdasmaKLIEEGREVERGLTAArdqafltIKEREAETSKLRSEAEALSSKVILAEE- 846
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARL--------DSLERLQENLEGFSEG-------VKALLKNQSGLSGILGVLSELISVDEGy 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  847 AKAIELAkkddemqvLSKEMKQIQMElgTVKKAKDDMELDLQSSIEKRQeQLLVLRFQMNELEESANQKETEIEVLQTKL 926
Cdd:TIGR02168  536 EAAIEAA--------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVT-FLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  927 SNKDEELKAFclhEKV------------EREELQRQLKQeedrcLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIH 994
Cdd:TIGR02168  605 KDLVKFDPKL---RKAlsyllggvlvvdDLDNALELAKK-----LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  995 SGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKvsddal 1074
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA------ 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1075 iHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLgtaSALASEKDSQLELL 1154
Cdd:TIGR02168  751 -QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1155 HAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLhaeLKERDSLRIQAAEMEARHKELEESI 1234
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEEL 903

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKE------------RDGLRIQAAEMEARHKELEESIAQLQARL 1293
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGlevridnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRL 974
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 944-1533 2.17e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.17e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  944 REELQRQLKQ-EED-----RCLMYKQEIVVKDKEVNFLKMAMV-AKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQ 1016
Cdd:COG1196    195 LGELERQLEPlERQaekaeRYRELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1017 AISTLEIRLSDAHRLLEEKASSIEmqtsqvmQLQRDLSTEQERVVSLEQsmkvsddalihcklEKEALKNEVTSLQELAE 1096
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELA-------RLEQDIARLEERRRELEE--------------RLEELEEELAELEEELE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1097 KLKGELEELKREHENLRLQVAETE-TLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARH 1175
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEaELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1176 KELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQL 1255
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1256 ESLHAELKERDGLR--------------------------------IQAAEMEARHKELEESIAQLQARLGTASALASGK 1303
Cdd:COG1196    494 LLLLEAEADYEGFLegvkaalllaglrglagavavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1304 QSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQL-DSLHNEMNEKDHVIKTQHMELESTVTQLK 1382
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLgRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1383 EQLHTATSLAAVQKRVN-----EKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEH 1457
Cdd:COG1196    654 EGGSAGGSLTGGSRRELlaallEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033 1458 LNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKvSLESKLKLAGqelSV-LLPLQECKAENERLiGDLQEQLQ 1533
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELE-RLEREIEALG---PVnLLAIEEYEELEERY-DFLSEQRE 805
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 213-539 2.58e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.58e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  213 RKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQC 292
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  293 QELKTNKTQM----ERKIDDLTEENGILSVQMREIFSRLSSAE-AAVQKLSAEQESSQVEWESKRGLLESELGQALSQKE 367
Cdd:TIGR02169  750 EQEIENVKSElkelEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  368 YLNEQIQILQGKISILED-ELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEvek 446
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEqIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE--- 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  447 tKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVS---------LEAQIEALTADIASLTE----AVQQRELAV 513
Cdd:TIGR02169  907 -ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIRALEPvnmlAIQEYEEVL 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1338812033  514 TNFS------QKVDVERKRVEKLTEEMEKQER 539
Cdd:TIGR02169  986 KRLDelkekrAKLEEERKAILERIEEYEKKKR 1017
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 201-1134 9.87e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.00  E-value: 9.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQLVQEREMRdELERELASRSQVITEREMQVSQLQhrvQRMMRDSEEQEQQPKEIEQLQRKNEG 280
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNELH-EKQKFYLRQSVIDLQTKLQEMQME---RDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  281 LLTRLHDVLKQcQELKTNKTQMERKIDDLTEENGILsvqmREIFSRLSSAEAAVQKLSAEQES-SQVEWESkrglleseL 359
Cdd:pfam15921  152 HELEAAKCLKE-DMLEDSNTQIEQLRKMMLSHEGVL----QEIRSILVDFEEASGKKIYEHDSmSTMHFRS--------L 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  360 GQALSQK-EYLNEQIQILQGKISILEDELSKAKAETLGGGEVMgpimewerlnqeiadlnhkLSQLQEIIIQLQKEkkei 438
Cdd:pfam15921  219 GSAISKIlRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL-------------------LQQHQDRIEQLISE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  439 emmYEVEKTKFeAEKArleelvselnkmltvqrgerealeQALREQRVSLEAQIEALTAdiaslteavQQRELAVTNFSQ 518
Cdd:pfam15921  276 ---HEVEITGL-TEKA------------------------SSARSQANSIQSQLEIIQE---------QARNQNSMYMRQ 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  519 KVDVErKRVEKLTEEMEKQERFAQKTIQELHERVdhlgSVLNSKEEEARSNAEEWARERHEISRQQEVLMEarETISRER 598
Cdd:pfam15921  319 LSDLE-STVSQLRSELREAKRMYEDKIEELEKQL----VLANSELTEARTERDQFSQESGNLDDQLQKLLA--DLHKREK 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  599 DaiateyqhFQQEKEEvacklNQQIVLLEEQQSVEwslLSELRKEKQELEQKVSSIEAIVDNLRTRCHGlelDSEAQRAS 678
Cdd:pfam15921  392 E--------LSLEKEQ-----NKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSECQG---QMERQMAA 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  679 HQEEVESLKRklheAESILGVYEGKLADHQKIVEEHIALRDELSAAaecakglrdelevERSKhkETLAAKLQSKSQMME 758
Cdd:pfam15921  453 IQGKNESLEK----VSSLTAQLESTKEMLRKVVEELTAKKMTLESS-------------ERTV--SDLTASLQEKERAIE 513

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  759 EMReleektqnmsvemqhlgqqlSKVQQEKMRVDASMaklieegrevergltaardQAFLTIKEREAETSKLRSEAEALs 838
Cdd:pfam15921  514 ATN--------------------AEITKLRSRVDLKL-------------------QELQHLKNEGDHLRNVQTECEAL- 553

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  839 sKVILAEEAKAIELAKKDDEmqvlskEMKQIQMELGTVKKAKDDMELDLQSSIEKRqeqllvlRFQMNELEESANQKETE 918
Cdd:pfam15921  554 -KLQMAEKDKVIEILRQQIE------NMTQLVGQHGRTAGAMQVEKAQLEKEINDR-------RLELQEFKILKDKKDAK 619

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  919 IEVLQTKLSNKDEElKAFCLHEKVEREELQRQLKQEEDRCLmykqeivvkdkevnflkmamvakeEEINSLMQSIHSGEE 998
Cdd:pfam15921  620 IRELEARVSDLELE-KVKLVNAGSERLRAVKDIKQERDQLL------------------------NEVKTSRNELNSLSE 674

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  999 KASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIE-MQTSQ------VMQLQRDLSTEQERVVSLEQSMKVSD 1071
Cdd:pfam15921  675 DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKsMEGSDghamkvAMGMQKQITAKRGQIDALQSKIQFLE 754

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1072 DALIHCKLEKEALKNEVTSL-QELA------EKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQ 1134
Cdd:pfam15921  755 EAMTNANKEKHFLKEEKNKLsQELStvatekNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 211-664 3.15e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELAsrsqvitEREMQVSQLQHRVQRMMRDSEEQEQQpkeIEQLQRKNEGLLTRLHDVLK 290
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELA-------EAEEELEELAEELLEALRAAAELAAQ---LEELEEAEEALLERLERLEE 421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQMERKIDDLTEENgilsVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLN 370
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  371 EQIQILQGKisiLEDELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEmmyEVEKTKFE 450
Cdd:COG1196    498 EAEADYEGF---LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAI---EYLKAAKA 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  451 AEKARLeelvsELNKMltvqrGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKL 530
Cdd:COG1196    572 GRATFL-----PLDKI-----RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT 641

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  531 TEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQ 610
Cdd:COG1196    642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1338812033  611 EKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTR 664
Cdd:COG1196    722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1796-1844 1.84e-11

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 61.07  E-value: 1.84e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1796 LLSLPGYRRSTTHS------HVPPRNINTYGVGA-ENEPDVTDDWKRIVELQARNK 1844
Cdd:cd22298      1 LLSLPGYRPSTRSStrrsqsSSATGGRSTFYMGTcQDEPEHLDDWNRIAELQQRNR 56
PTZ00121 PTZ00121
MAEBL; Provisional
 523-1232 3.77e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.77e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  523 ERKRVEKLTEEMEKQERFAQKTIQELHERvdhlgsvlNSKEEEARSNAEEwARERHEISRQQEV--LMEARETISRERDA 600
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEE--------ARKAEEAKKKAED-ARKAEEARKAEDArkAEEARKAEDAKRVE 1155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  601 IATEYQhfQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEkqeleQKVSSIEAI--VDNLRtRCHGLELDSEAQRAS 678
Cdd:PTZ00121  1156 IARKAE--DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKA-----EDARKAEAArkAEEER-KAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  679 HQEEVESLKRKLHEAESILGV-YEGKLADHQKIVEEHIALRDELSAAAECAKGlrDELEversKHKETLAAKLQSKSQMM 757
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEErNNEEIRKFEEARMAHFARRQAAIKAEEARKA--DELK----KAEEKKKADEAKKAEEK 1301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  758 EEMRELEEKTQnmsvEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVErgltAARDQAFLTIKEREAETSKLRSEAEAL 837
Cdd:PTZ00121  1302 KKADEAKKKAE----EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE----AAKAEAEAAADEAEAAEEKAEAAEKKK 1373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  838 SSKVILAEEAKA-IELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKE 916
Cdd:PTZ00121  1374 EEAKKKADAAKKkAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA 1453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  917 TEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIVVKD---------------KEVNFLKMAMVA 981
Cdd:PTZ00121  1454 EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeakkkadeakkaeeaKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  982 KEEEINSLMQSIHSGEE--KASAFQDLQEKRHEEQKQaisTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQrdlstEQER 1059
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADElkKAEELKKAEEKKKAEEAK---KAEEDKNMALRKAEEAKKAEEARIEEVMKLY-----EEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1060 VVSLEQSMKVSDDALIHCKLEK-EALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETEtlhnKSEERIAQLQARLG 1138
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA----KKAEEDKKKAEEAK 1681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1139 TASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRI 1218
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH 1761

                          730
                   ....*....|....
gi 1338812033 1219 QAAEMEARHKELEE 1232
Cdd:PTZ00121  1762 LKKEEEKKAEEIRK 1775
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1084-1600 6.30e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1084 LKNEVTSLQELAEKLKGELEELKREHEN-----LRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAEL 1158
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 KERDSlriqaaeMEARH-KELEESIAQLQARLGTASALASEK----DSQLELLHAELKER---------------DSLRI 1218
Cdd:pfam15921  309 RNQNS-------MYMRQlSDLESTVSQLRSELREAKRMYEDKieelEKQLVLANSELTEArterdqfsqesgnldDQLQK 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKEL---EESIAQLQAQLGTASVLASEKDSQLESLHAELKERDGLrIQAAEMEARhKELEESIAQLQAR--- 1292
Cdd:pfam15921  382 LLADLHKREKELsleKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL-LKAMKSECQ-GQMERQMAAIQGKnes 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1293 LGTASALASGKQSELDLLHKEVREREKLRI--------------------RAVEVEEAQHKELEERV----TEASTLASE 1348
Cdd:pfam15921  460 LEKVSSLTAQLESTKEMLRKVVEELTAKKMtlessertvsdltaslqekeRAIEATNAEITKLRSRVdlklQELQHLKNE 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1349 R------KSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSL----AAVQKRVNE-------------KLNED 1405
Cdd:pfam15921  540 GdhlrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqvekAQLEKEINDrrlelqefkilkdKKDAK 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1406 IRRLDVvRQESMERDALRIRAIEAEDLKR-KEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQ----TLLSMK 1480
Cdd:pfam15921  620 IRELEA-RVSDLELEKVKLVNAGSERLRAvKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEemetTTNKLK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1481 ESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQL 1560
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL 778

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1338812033 1561 LEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKL 1600
Cdd:pfam15921  779 STVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASL 818
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 981-1699 6.35e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 6.35e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  981 AKEEEINSLMQSIHSGEEKASAFQDLQEkrhEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERV 1060
Cdd:TIGR02169  191 LIIDEKRQQLERLRREREKAERYQALLK---EKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1061 VSLEQSMKvSDDALIHCKLEKE--ALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLG 1138
Cdd:TIGR02169  268 EEIEQLLE-ELNKKIKDLGEEEqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1139 TasaLASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLgtaSALASEKDSQLELLHAELKERDSLRI 1218
Cdd:TIGR02169  347 E---ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL---EKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELK--ERDGLRIQA--AEMEARHKELEESIAQLQARLG 1294
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSkyEQELYDLKEeyDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1295 TASALASGKQSELDLLHK-------------EVREREKL--------RIRAVEVEEaqhkelEERVTEASTLASERKS-- 1351
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKAsiqgvhgtvaqlgSVGERYATaievaagnRLNNVVVED------DAVAKEAIELLKRRKAgr 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1352 ----QLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERD------- 1420
Cdd:TIGR02169  575 atflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGElfeksga 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1421 -----------ALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEV 1489
Cdd:TIGR02169  655 mtggsraprggILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1490 SQRVKVSLESKLKLAGQELsvlLPLQECKAENERLIGDLQEQLQAKTEAMKHCKA-----QVQMAKTHYNGKKQQLLEVQ 1564
Cdd:TIGR02169  735 LKERLEELEEDLSSLEQEI---ENVKSELKELEARIEELEEDLHKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1565 EKAQTLENTLESRDQEVKVLRSEMKLLQ----------------IELDQAKLSE------------KDLALKVNSLQAQV 1616
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQeqridlkeqiksiekeIENLNGKKEEleeeleeleaalRDLESRLGDLKKER 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1617 DYADRQLREyAKHGIDTTlntckpPSQEERSEKLADLSKDSLDfCLDDSLSATRKPLAHEESSTPLVRSSERLRAKRRAL 1696
Cdd:TIGR02169  892 DELEAQLRE-LERKIEEL------EAQIEKKRKRLSELKAKLE-ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRV 963


                   ...
gi 1338812033 1697 GDD 1699
Cdd:TIGR02169  964 EEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1203-1538 9.28e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 9.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1203 LELLHAELKER-DSLRIQA--AEmeaRHKELEESIAQLQAQLGTAsvlasekdsQLESLHAELKErdgLRIQAAEMEARH 1279
Cdd:COG1196    191 LEDILGELERQlEPLERQAekAE---RYRELKEELKELEAELLLL---------KLRELEAELEE---LEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1280 KELEESIAQLQARLGTASAlasgKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEAstlaserKSQLDSLHNE 1359
Cdd:COG1196    256 EELEAELAELEAELEELRL----ELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL-------EERLEELEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1360 MNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESME---RDALRIRAIEAEDLKRKE 1436
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEElaeELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1437 MEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQE 1516
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340
                   ....*....|....*....|..
gi 1338812033 1517 cKAENERLIGDLQEQLQAKTEA 1538
Cdd:COG1196    485 -ELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1072-1605 2.10e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 2.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1072 DALIHCKLEKEALKNEVTSLQEL---AEKLKGELEELKREHENLRLQVAETETLHNK---SEERIAQLQARLGTASALAS 1145
Cdd:PRK03918   138 DAILESDESREKVVRQILGLDDYenaYKNLGEVIKEIKRRIERLEKFIKRTENIEELikeKEKELEEVLREINEISSELP 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1146 EKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEA 1225
Cdd:PRK03918   218 ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1226 RHKELEESIAQLQaqlgTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASgKQS 1305
Cdd:PRK03918   298 LSEFYEEYLDELR----EIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-KKE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1306 ELDLLHKE---------VREREKLRIRAVEVEEAQhKELEERVTEASTLASERKSQLDSLHN------------EMNEKD 1364
Cdd:PRK03918   373 ELERLKKRltgltpeklEKELEELEKAKEEIEEEI-SKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRK 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1365 HVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDiRRLDVVRQ--ESMERDALRIRAIEAEDLKRK-----EM 1437
Cdd:PRK03918   452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE-SELIKLKElaEQLKELEEKLKKYNLEELEKKaeeyeKL 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1438 EETIVKLKSEILTHTTKLEHLNKWhQQQLSVLRNENQTLLSMKESMVKE---------QEVSQRVKvslesKLKLAGQEL 1508
Cdd:PRK03918   531 KEKLIKLKGEIKSLKKELEKLEEL-KKKLAELEKKLDELEEELAELLKEleelgfesvEELEERLK-----ELEPFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1509 SVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEvqEKAQTLENTLESRDQEVKVLRSEM 1588
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAEL 682

                          570
                   ....*....|....*..
gi 1338812033 1589 KLLQIELDQAKLSEKDL 1605
Cdd:PRK03918   683 EELEKRREEIKKTLEKL 699
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 209-691 8.43e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 8.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  209 QFRLRKLQKQLVQEREMR-----DELERELasrsqviTEREMQVSQLQHRVQRMmrDSEEQEQQPKEIEQLQRKNEGL-- 281
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGnsitiDHLRREL-------DDRNMEVQRLEALLKAM--KSECQGQMERQMAAIQGKNESLek 462

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  282 -------LTRLHDVLKQC-QELKTNKTQME---RKIDDLTEengilSVQMREifSRLSSAEAAVQKLSAEQESSQVEWES 350
Cdd:pfam15921  463 vssltaqLESTKEMLRKVvEELTAKKMTLEsseRTVSDLTA-----SLQEKE--RAIEATNAEITKLRSRVDLKLQELQH 535

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  351 KRGlLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMGPI-MEWERLNQEIADLNHKLSQLqeiii 429
Cdd:pfam15921  536 LKN-EGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqVEKAQLEKEINDRRLELQEF----- 609

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  430 QLQKEKKEiemmyevekTKFEAEKARLEELvsELNKMLTVQRG-EREALEQALREQRVSLEAQIEALTADIASLTEavqQ 508
Cdd:pfam15921  610 KILKDKKD---------AKIRELEARVSDL--ELEKVKLVNAGsERLRAVKDIKQERDQLLNEVKTSRNELNSLSE---D 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  509 RELAVTNFSQKvdveRKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLM 588
Cdd:pfam15921  676 YEVLKRNFRNK----SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  589 EARETISRerdaiATEYQHFQQEKEEvacKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRChgl 668
Cdd:pfam15921  752 FLEEAMTN-----ANKEKHFLKEEKN---KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQF--- 820

                          490       500
                   ....*....|....*....|...
gi 1338812033  669 eldSEAQRASHQEEVESLKRKLH 691
Cdd:pfam15921  821 ---AECQDIIQRQEQESVRLKLQ 840
PLN02939 PLN02939
transferase, transferring glycosyl groups
 236-656 9.02e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.06  E-value: 9.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  236 RSQVITEREMQVSQlqhRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQcQELKTNKTQMERKIDDLTEENGI 315
Cdd:PLN02939    22 PFYLPSRRRLAVSC---RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQ-LENTSLRTVMELPQKSTSSDDDH 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  316 LSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRG----------LLESELGQALSQKEYLNEQIQILQGKISILED 385
Cdd:PLN02939    98 NRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGmiqnaeknilLLNQARLQALEDLEKILTEKEALQGKINILEM 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  386 ELSKAKAET-LGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEElVSELN 464
Cdd:PLN02939   178 RLSETDARIkLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIE-VAETE 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  465 KMLTVQRGEREALEQALREqrvsLEAQIEALTADIASLTeavqqrelavtnfSQKVDVERKRVEKLTEEMEKQERFAQKT 544
Cdd:PLN02939   257 ERVFKLEKERSLLDASLRE----LESKFIVAQEDVSKLS-------------PLQYDCWWEKVENLQDLLDRATNQVEKA 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  545 I------QELHERVDHLgsvlnsKEEEARSNAEEWARERHEISRQQEVLMEAR-ETISRERDAIATEYQHFQQEKEEVAC 617
Cdd:PLN02939   320 AlvldqnQDLRDKVDKL------EASLKEANVSKFSSYKVELLQQKLKLLEERlQASDHEIHSYIQLYQESIKEFQDTLS 393

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1338812033  618 KLNQQIVLLEEQQSVE------WSLLSeLRKEKQELEQKVSSIEA 656
Cdd:PLN02939   394 KLKEESKKRSLEHPADdmpsefWSRIL-LLIDGWLLEKKISNNDA 437
CH pfam00307
Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal ...
 8-44 2.38e-03

Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal transduction proteins. The CH domain is involved in actin binding in some members of the family. However in calponins there is evidence that the CH domain is not involved in its actin binding activity. Most member proteins have from two to four copies of the CH domain, however some proteins such as calponin have only a single copy.


Pssm-ID: 425596 [Multi-domain]  Cd Length: 109  Bit Score: 39.58  E-value: 2.38e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1338812033    8 EEALLNWINSlHLDSPIDHIFL------LQDGVILVKLIHKLK 44
Cdd:pfam00307    4 EKELLRWINS-HLAEYGPGVRVtnfttdLRDGLALCALLNKLA 45
CH smart00033
Calponin homology domain; Actin binding domains present in duplicate at the N-termini of ...
 9-70 3.12e-03

Calponin homology domain; Actin binding domains present in duplicate at the N-termini of spectrin-like proteins (including dystrophin, alpha-actinin). These domains cross-link actin filaments into bundles and networks. A calponin homology domain is predicted in yeasst Cdc24p.


Pssm-ID: 214479 [Multi-domain]  Cd Length: 101  Bit Score: 39.22  E-value: 3.12e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033     9 EALLNWINS-LHLDSPIDHIFL---LQDGVILVKLIHKLKKQEIGVDAVLELPLQ-GRLDFISAFLQ 70
Cdd:smart00033    1 KTLLRWVNSlLAEYDKPPVTNFssdLKDGVALCALLNSLSPGLVDKKKVAASLSRfKKIENINLALS 67
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 5-153 2.28e-63

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 212.43  E-value: 2.28e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033    5 RKKEEALLNWINSLHLDSPIDHIFLLQDGVILVKLIHKLKKQEIGvDAVLELPLQGRLDFISAFLQKDCRYKADRGTIVS 84
Cdd:cd22224      1 NTKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEE-EQILDLSVEERLEFISSFLEGDCRFNSSQGTLVS 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033   85 WDNIVLGKNLDVELSKVVVLLLYHSLMNGLLGLDRLGYDIELELADVLRFVLNNEDSLYLSDNLEKILK 153
Cdd:cd22224     80 WQKILQGENLELELAKVLLLLLYHSMMNNNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 454-1293 3.74e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.30  E-value: 3.74e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  454 ARLEELVSELNKMLtvQRGEREAlEQALREQRvsLEAQIEALtadiaslteavqQRELAVTNFSQKVDvERKRVEKLTEE 533
Cdd:TIGR02168  189 DRLEDILNELERQL--KSLERQA-EKAERYKE--LKAELREL------------ELALLVLRLEELRE-ELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  534 MEKQERFAQKTIQELHERVDHLGS---VLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQ 610
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLevsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  611 EKEEVACKLNQQIVLLEEQQSVEWSL---LSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELdseaQRASHQEEVESLK 687
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLeaeLEELEAELEELESRLEELEEQLETLRSKVAQLEL----QIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  688 RKLHEAEsilgvyegklADHQKIVEEHIALRDELSAAAecakglRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKT 767
Cdd:TIGR02168  407 ARLERLE----------DRRERLQQEIEELLKKLEEAE------LKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  768 QNMSVEMQHLGQQLSKVQQEKmrvdasmaKLIEEGREVERGLTAArdqafltIKEREAETSKLRSEAEALSSKVILAEE- 846
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARL--------DSLERLQENLEGFSEG-------VKALLKNQSGLSGILGVLSELISVDEGy 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  847 AKAIELAkkddemqvLSKEMKQIQMElgTVKKAKDDMELDLQSSIEKRQeQLLVLRFQMNELEESANQKETEIEVLQTKL 926
Cdd:TIGR02168  536 EAAIEAA--------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVT-FLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  927 SNKDEELKAFclhEKV------------EREELQRQLKQeedrcLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIH 994
Cdd:TIGR02168  605 KDLVKFDPKL---RKAlsyllggvlvvdDLDNALELAKK-----LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  995 SGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKvsddal 1074
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA------ 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1075 iHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLgtaSALASEKDSQLELL 1154
Cdd:TIGR02168  751 -QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL---TLLNEEAANLRERL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1155 HAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLhaeLKERDSLRIQAAEMEARHKELEESI 1234
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEEL 903

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKE------------RDGLRIQAAEMEARHKELEESIAQLQARL 1293
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGlevridnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRL 974
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 266-1186 1.86e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.91  E-value: 1.86e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  266 QQPKEIEQLQRKNEGLLTRLHDVLKqcqELKTNKTQMERKIDdlteengiLSVQMREIFSRLSSAEAAVQKLSAEQEssq 345
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILN---ELERQLKSLERQAE--------KAERYKELKAELRELELALLVLRLEEL--- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  346 vewESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEvmgpimEWERLNQEIADLNHKLSQLQ 425
Cdd:TIGR02168  238 ---REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK------ELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  426 EIIIQLQKEKKEIEMM----------YEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREqrvsLEAQIEAL 495
Cdd:TIGR02168  309 ERLANLERQLEELEAQleeleskldeLAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE----LEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  496 TADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKT-IQELHERVDHLGSVLNSKEEEARSNAEEWA 574
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALE 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  575 RERHEISRQQEVLMEARETISRER---DAIATEYQHFQQEKEEVACKLNQQivlleEQQSVEWSLLSELRKEKQELEQKV 651
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQ-----SGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  652 S--------------------SIEAIVDNLRTRCHGLELDSEAQRASHQEEVESLKRKlheaesilGVYEGKLADHQKIV 711
Cdd:TIGR02168  540 EaalggrlqavvvenlnaakkAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNI--------EGFLGVAKDLVKFD 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  712 EEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSveMQHLGQQLSKVQQEkmrv 791
Cdd:TIGR02168  612 PKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRREIEELEEK---- 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  792 dasMAKLIEEGREVERGLTAARDQafltIKEREAETSKLRSEAEALSSKVILAEEakaiELAKKDDEMQVLSKEMKQIQM 871
Cdd:TIGR02168  686 ---IEELEEKIAELEKALAELRKE----LEELEEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  872 ELgtvkKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKafclhekvereELQRQL 951
Cdd:TIGR02168  755 EL----TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT-----------LLNEEA 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  952 KQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDlQEKRHEEQKQAISTLEIRLSDAHRL 1031
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES-ELEALLNERASLEEALALLRSELEE 898

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1032 LEEKASSIEmqtSQVMQLQRDLSTEQERVVSLEqsmkvsddalihckLEKEALKNEVTSLQE-LAEKLKGELEELKREHE 1110
Cdd:TIGR02168  899 LSEELRELE---SKRSELRRELEELREKLAQLE--------------LRLEGLEVRIDNLQErLSEEYSLTLEEAEALEN 961

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033 1111 nlrlqvaETETLHNKSEERIAQLQ---ARLGTASALASEKdsqlellHAELKERDSlriqaaEMEARHKELEESIAQLQ 1186
Cdd:TIGR02168  962 -------KIEDDEEEARRRLKRLEnkiKELGPVNLAAIEE-------YEELKERYD------FLTAQKEDLTEAKETLE 1020
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 774-1576 5.70e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.70e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  774 MQHLGQQLSKVQQEKmrvdasmaKLIEEGREVERGLTAARdqafltIKEREAETSKLRSEAEALSSKV-ILAEEAKAIE- 851
Cdd:TIGR02168  202 LKSLERQAEKAERYK--------ELKAELRELELALLVLR------LEELREELEELQEELKEAEEELeELTAELQELEe 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  852 -LAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELD----------LQSSIEKRQEQLLVLRFQMNELEESANQKETEIE 920
Cdd:TIGR02168  268 kLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqilrerlanLERQLEELEAQLEELESKLDELAEELAELEEKLE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  921 VLQTKLSNKDEELKAFclheKVEREELQRQLKQeedrclmykqeivvKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKA 1000
Cdd:TIGR02168  348 ELKEELESLEAELEEL----EAELEELESRLEE--------------LEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1001 SAFQDLQEKRHEEQKQAISTL-EIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKL 1079
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVaetETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELK 1159
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS---ELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1160 ERDSLR--------IQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRiQAAEMeARHKELE 1231
Cdd:TIGR02168  567 QNELGRvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD-NALEL-AKKLRPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1232 ESIAQLQAQL----GTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSEL 1307
Cdd:TIGR02168  645 YRIVTLDGDLvrpgGVITGGSAKTNSSILERRREIEE---LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1308 DLLHKEVREREKlRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHT 1387
Cdd:TIGR02168  722 EELSRQISALRK-DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1388 ATS-LAAVQKRVNEkLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEHLN---KWHQ 1463
Cdd:TIGR02168  801 LREaLDELRAELTL-LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELEselEALL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1464 QQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVL-LPLQECKAENERLIGDLQEQLQAKTEamkhc 1542
Cdd:TIGR02168  880 NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLeLRLEGLEVRIDNLQERLSEEYSLTLE----- 954

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1338812033 1543 kaqvqMAKTHYNGKKQQLLEVQEKAQTLENTLES 1576
Cdd:TIGR02168  955 -----EAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 944-1533 2.17e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.17e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  944 REELQRQLKQ-EED-----RCLMYKQEIVVKDKEVNFLKMAMV-AKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQ 1016
Cdd:COG1196    195 LGELERQLEPlERQaekaeRYRELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1017 AISTLEIRLSDAHRLLEEKASSIEmqtsqvmQLQRDLSTEQERVVSLEQsmkvsddalihcklEKEALKNEVTSLQELAE 1096
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELA-------RLEQDIARLEERRRELEE--------------RLEELEEELAELEEELE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1097 KLKGELEELKREHENLRLQVAETE-TLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARH 1175
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEaELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1176 KELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQL 1255
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1256 ESLHAELKERDGLR--------------------------------IQAAEMEARHKELEESIAQLQARLGTASALASGK 1303
Cdd:COG1196    494 LLLLEAEADYEGFLegvkaalllaglrglagavavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1304 QSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQL-DSLHNEMNEKDHVIKTQHMELESTVTQLK 1382
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLgRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1383 EQLHTATSLAAVQKRVN-----EKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEH 1457
Cdd:COG1196    654 EGGSAGGSLTGGSRRELlaallEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033 1458 LNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKvSLESKLKLAGqelSV-LLPLQECKAENERLiGDLQEQLQ 1533
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELE-RLEREIEALG---PVnLLAIEEYEELEERY-DFLSEQRE 805
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 597-1338 5.40e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.82  E-value: 5.40e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  597 ERDAIATEYQHFQQEKEEV---ACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELD-- 671
Cdd:TIGR02168  226 ELALLVLRLEELREELEELqeeLKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkq 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  672 --------SEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVE----EHIALRDELSAAAECAKGLRDELEVER 739
Cdd:TIGR02168  306 ilrerlanLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELEsleaELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  740 SKHKETLAAKLQSKSQMmeemreleektQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLieEGREVERGLTAARDQAFLT 819
Cdd:TIGR02168  386 SKVAQLELQIASLNNEI-----------ERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  820 IKEREAETSKLRSEAEAL--SSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQS-----SIE 892
Cdd:TIGR02168  453 QEELERLEEALEELREELeeAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlseliSVD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  893 KRQEQLL--VLRFQMNELE-ESANQKETEIEVLQTKLSNKdeelKAFCLHEKVEREELQ---RQLKQEEDRCLMYKQEIV 966
Cdd:TIGR02168  533 EGYEAAIeaALGGRLQAVVvENLNAAKKAIAFLKQNELGR----VTFLPLDSIKGTEIQgndREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  967 VKDKEVNFLkmamvakeeeINSLMQSIHSGEEKASAFQDLQEKRHEEQ--------------------KQAISTLE--IR 1024
Cdd:TIGR02168  609 KFDPKLRKA----------LSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaKTNSSILErrRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1025 LSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEE 1104
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1105 LKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQ 1184
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL---LNEEAANLRERLESLERRIAA 835

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1185 LQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKE 1264
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEE---LEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1265 ----RDGLRIQAAEMEARHKELEESIAQLQARL--------GTASALASGKQSELDLLHKEVREREKLRIRAVEVEEA-- 1330
Cdd:TIGR02168  913 lrreLEELREKLAQLELRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAai 992


                   ....*....
gi 1338812033 1331 -QHKELEER 1338
Cdd:TIGR02168  993 eEYEELKER 1001
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 885-1448 1.66e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.66e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  885 LDLQSSIEKRQEQLLVLRFQmnELEESANQKETEIEVLQTklsnkdeelkafclhekvEREELQRQLKQEEDRCLMYKQE 964
Cdd:COG1196    216 RELKEELKELEAELLLLKLR--ELEAELEELEAELEELEA------------------ELEELEAELAELEAELEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  965 IVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQ----------DLQEKRHEEQKQAISTLEIRLSDAHRLLEE 1034
Cdd:COG1196    276 LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEerleeleeelAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1035 KASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRL 1114
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1115 QVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAemeARHKELEESIAQLQARLGTASA 1194
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA---ARLLLLLEAEADYEGFLEGVKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1195 LASEKDSQL------ELLHAELKERDSLRIQAAEMEARHKELEESIAQ------LQAQLGTASVLASEKDSQLESlhAEL 1262
Cdd:COG1196    513 ALLLAGLRGlagavaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaieylKAAKAGRATFLPLDKIRARAA--LAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1263 KERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEA 1342
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1343 STLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDAL 1422
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                          570       580
                   ....*....|....*....|....*.
gi 1338812033 1423 RIRAIEAEDLKRKEMEETIVKLKSEI 1448
Cdd:COG1196    751 EALEELPEPPDLEELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 424-1289 1.80e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.91  E-value: 1.80e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  424 LQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELnkmltvqrgerealeQALREQRVSLEAQIEALTADIASLT 503
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEK---------------EALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  504 EAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQerfAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWAR---ERHEI 580
Cdd:TIGR02169  258 EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR---VKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  581 SRQQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQqivllEEQQSVEWslLSELRKEKQELEQKVSSIEAIVDN 660
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE-----VDKEFAET--RDELKDYREKLEKLKREINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  661 LRtrchglELDSEAQRAShqEEVESLKRKLheaesilgvyEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERS 740
Cdd:TIGR02169  408 LD------RLQEELQRLS--EELADLNAAI----------AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  741 KHKetlaaklqsksqmmeemreleektqNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGRE---VERGLTAARDQAF 817
Cdd:TIGR02169  470 ELY-------------------------DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraVEEVLKASIQGVH 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  818 LTIKE----REAETSKLRSEAEALSSKVILAEE---AKAIELAKKD----------DEMQVLSKEMKQIQMElGTVKKAK 880
Cdd:TIGR02169  525 GTVAQlgsvGERYATAIEVAAGNRLNNVVVEDDavaKEAIELLKRRkagratflplNKMRDERRDLSILSED-GVIGFAV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  881 DDMELDLQ---------------SSIEKRQEQLLVLRFQMNE---LEES--------------ANQKETEIEVLQtkLSN 928
Cdd:TIGR02169  604 DLVEFDPKyepafkyvfgdtlvvEDIEAARRLMGKYRMVTLEgelFEKSgamtggsraprggiLFSRSEPAELQR--LRE 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  929 KDEELK---AFCLHEKVEREELQRQLKQEEDRClmyKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQD 1005
Cdd:TIGR02169  682 RLEGLKrelSSLQSELRRIENRLDELSQELSDA---SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1006 LQ---EKRHEEQKQAISTLEIRLSDAHRLLEEkassiemqtSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKE 1082
Cdd:TIGR02169  759 ELkelEARIEELEEDLHKLEEALNDLEARLSH---------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1083 ALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASalasekdsqlellhaelKERD 1162
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK-----------------KERD 892

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1163 SLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAqLG 1242
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA-LE 971

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1338812033 1243 TASVLAsekdsqLESLHAELKERDGLRIQAAEMEARHKELEESIAQL 1289
Cdd:TIGR02169  972 PVNMLA------IQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 636-1385 7.18e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 7.18e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  636 LLSELRKEKQELEQKVSSIE---AIVDNLRTRCHGLELDS----EAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQ 708
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAErykELKAELRELELALLVLRleelREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  709 KIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEK 788
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  789 MRVDASMAKLIEEGREVERGLTAARDQafltIKEREAETSKLRSEAEALSSKVILAEEakaiELAKKDDEMQVLSKEMKQ 868
Cdd:TIGR02168  354 ESLEAELEELEAELEELESRLEELEEQ----LETLRSKVAQLELQIASLNNEIERLEA----RLERLEDRRERLQQEIEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  869 IQMELGTVKKAKDDMELD-LQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAfclhekvereeL 947
Cdd:TIGR02168  426 LLKKLEEAELKELQAELEeLEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-----------L 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  948 QRQLKQEEDrclmykqeivvKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASA--------FQDLQEKRHEEQKQAIS 1019
Cdd:TIGR02168  495 ERLQENLEG-----------FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAieaalggrLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1020 TLE---------IRLSD-AHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSM----KVSDDALIHCKLEKEALK 1085
Cdd:TIGR02168  564 FLKqnelgrvtfLPLDSiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1086 NE--VTSLQEL----------AEKLKGELEELKREHENLRLQVAETEtlhnkseERIAQLQARLGTASALASEKDSQLEL 1153
Cdd:TIGR02168  644 GYriVTLDGDLvrpggvitggSAKTNSSILERRREIEELEEKIEELE-------EKIAELEKALAELRKELEELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1154 LHAELkerDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELkerdslriqaAEMEARHKELEES 1233
Cdd:TIGR02168  717 LRKEL---EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL----------EEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1234 IAQLQAQLGTASVLASEKDSQLESLHAELKE-----------RDGLRIQAAEMEARHKELEESIAQLQARLGTASALASG 1302
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLlneeaanlrerLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1303 KQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKsQLDSLHNEMNEKDHVIKTQHMELESTVTQLK 1382
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS-ELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ...
gi 1338812033 1383 EQL 1385
Cdd:TIGR02168  943 ERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-936 1.15e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 1.15e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEREMQVS-------------------------QLQHRVQRMMRDSEEQE 265
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSeleeeieelqkelyalaneisrleqQKQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  266 QQPKEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDdlteengilsvQMREIFSRLSSAEAAVQKLSAEQESSQ 345
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE-----------ELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  346 VEWESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLgggevmgpIMEWERLNQEIADLNHKLSQLQ 425
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL--------QAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  426 EIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALRE--------QRVSLEAQIE-ALT 496
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGYEaAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  497 ADIAS-----LTEAVQQRELAVtNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARS--- 568
Cdd:TIGR02168  541 AALGGrlqavVVENLNAAKKAI-AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKals 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  569 -------------NAEEWARERHEISR---QQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSV 632
Cdd:TIGR02168  620 yllggvlvvddldNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  633 ewslLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVE 712
Cdd:TIGR02168  700 ----LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  713 EHIALRDELSAAAECAKGLRDELEVERSKHKETLAAklqsKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVD 792
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAE----LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  793 ASMAKLIEEGREVERGLTAARDQAfltikereAETSKLRSEAEALSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQME 872
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESEL--------EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338812033  873 LGTVKKAKDDMELDLQSSIEKRQEQLLVLrfqMNELEESANQKETEIEVLQTKLSNKDEELKAF 936
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDNLQERLSEEYSLT---LEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 454-1363 1.16e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 93.59  E-value: 1.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  454 ARLEELVSELNKMLTVQRGEREALE--QALRE------------QRVSLEAQIEALTADIASLTEAVQQRElavtnfsqk 519
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAEryQALLKekreyegyellkEKEALERQKEAIERQLASLEEELEKLT--------- 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  520 vdverKRVEKLTEEMEKQERfaqkTIQELHERVDHLGSvlnskeeearsnaeewarerHEISRQQEVLMEARETISRERD 599
Cdd:TIGR02169  258 -----EEISELEKRLEEIEQ----LLEELNKKIKDLGE--------------------EEQLRVKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  600 AIATEyqhfQQEKEEVACKLNQQIVLLEEQQSVEWSL---LSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQR 676
Cdd:TIGR02169  309 SIAEK----ERELEDAEERLAKLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  677 ASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEhialRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQM 756
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEE----LADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  757 MEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGRE---VERGLTAARDQAFLTIKE----REAETSK 829
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraVEEVLKASIQGVHGTVAQlgsvGERYATA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  830 LRSEAEALSSKVILAEE---AKAIELAKKD----------DEMQVLSKEMKQIQMElGTVKKAKDDMELDLQ-------- 888
Cdd:TIGR02169  541 IEVAAGNRLNNVVVEDDavaKEAIELLKRRkagratflplNKMRDERRDLSILSED-GVIGFAVDLVEFDPKyepafkyv 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  889 -------SSIEKRQEQLlvLRFQMNELEESANQKETEIevlqTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDrclmy 961
Cdd:TIGR02169  620 fgdtlvvEDIEAARRLM--GKYRMVTLEGELFEKSGAM----TGGSRAPRGGILFSRSEPAELQRLRERLEGLKR----- 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  962 kqeivvkdkevnflkmamvakeeeinslmqsihsgeEKASAFQDLqekrhEEQKQAISTLEIRLSDAHRLLEEKASSIEm 1041
Cdd:TIGR02169  689 ------------------------------------ELSSLQSEL-----RRIENRLDELSQELSDASRKIGEIEKEIE- 726

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1042 qtsqvmQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQvaETET 1121
Cdd:TIGR02169  727 ------QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP--EIQA 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1122 LHNKSEERIAQLQARLgtASALASEKDSQLELLHAElKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDS 1201
Cdd:TIGR02169  799 ELSKLEEEVSRIEARL--REIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA 875

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1202 QLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKE 1281
Cdd:TIGR02169  876 ALRDLESRLGD---LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1282 LEESIAQLQArlgtasalasgkqseldlLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMN 1361
Cdd:TIGR02169  953 LEDVQAELQR------------------VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014


                   ..
gi 1338812033 1362 EK 1363
Cdd:TIGR02169 1015 KK 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 719-1524 1.30e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 1.30e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  719 DELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKL 798
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  799 IEEGREVErgltAARDQAFLTIKEREAETSKLRSEAEALSSKVilaeEAKAIELAKKDDEMQVLSKEMKQIQMELGTVKK 878
Cdd:TIGR02168  315 ERQLEELE----AQLEELESKLDELAEELAELEEKLEELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  879 AKDDMELdlqsSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKD-EELKAFCLHEKVEREELQRQLKQEEdr 957
Cdd:TIGR02168  387 KVAQLEL----QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELERLE-- 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  958 clmykQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQE--KRHEEQKQAISTLEIRLSDAHRLLEEK 1035
Cdd:TIGR02168  461 -----EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvKALLKNQSGLSGILGVLSELISVDEGY 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1036 ASSIEMQTSQVMQ--LQRDLSTEQERVVSLEQS---------MKVSDDALIHcKLEKEALKNEVTSLQELAEKLKGElEE 1104
Cdd:TIGR02168  536 EAAIEAALGGRLQavVVENLNAAKKAIAFLKQNelgrvtflpLDSIKGTEIQ-GNDREILKNIEGFLGVAKDLVKFD-PK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1105 LKREHENLRLQVAETETLHN--------KSEERIAQLQARLGTASALASEKDSQLELLhaelkeRDSLRIQAAEMEARHK 1176
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNalelakklRPGYRIVTLDGDLVRPGGVITGGSAKTNSS------ILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1177 ELEESIAQLQARLGTASALASEKDSQLELLHAELkerDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLE 1256
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKEL---EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1257 SLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREklriRAVEVEEAQHKELE 1336
Cdd:TIGR02168  765 ELEERLEE---AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR----ERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1337 ERVTEASTLASERKSQLDSLHNEMNEkdhvIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQES 1416
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEE----LEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1417 merdalrIRAIEAEDLKRKEMEETIVKLKSEIlthttklehlnkwhQQQLSVLRNENQTLLSMKESMVKEQEVSQRvkvS 1496
Cdd:TIGR02168  914 -------RRELEELREKLAQLELRLEGLEVRI--------------DNLQERLSEEYSLTLEEAEALENKIEDDEE---E 969

                          810       820       830
                   ....*....|....*....|....*....|...
gi 1338812033 1497 LESKLKLAGQELSVLLP-----LQECKAENERL 1524
Cdd:TIGR02168  970 ARRRLKRLENKIKELGPvnlaaIEEYEELKERY 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 561-1409 2.56e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.44  E-value: 2.56e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  561 SKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAiATEYQHFQQEKEEVACK--LNQQIVLLEEQQSVEwSLLS 638
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREK-AERYQALLKEKREYEGYelLKEKEALERQKEAIE-RQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  639 ELRKEKQ----ELEQKVSSIEAIVDNLRTRCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEH 714
Cdd:TIGR02169  248 SLEEELEklteEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  715 IALRDELSAAAEcakGLRDELEVERsKHKETLAAKLQSKSQMMEEMREleeKTQNMSVEMQHLGQQLSKVQQEKmrvdas 794
Cdd:TIGR02169  328 EAEIDKLLAEIE---ELEREIEEER-KRRDKLTEEYAELKEELEDLRA---ELEEVDKEFAETRDELKDYREKL------ 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  795 mAKLIEEGREVERGLTAARDQAfltiKEREAETSKLRSEAEALSSKvilaeeakaieLAKKDDEMQVLSKEMKQIQMELG 874
Cdd:TIGR02169  395 -EKLKREINELKRELDRLQEEL----QRLSEELADLNAAIAGIEAK-----------INELEEEKEDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  875 TVKKAKDDMEldlqssiekrqEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQ------ 948
Cdd:TIGR02169  459 QLAADLSKYE-----------QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtv 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  949 RQLKQEEDRCLM--------YKQEIVVKDKEV-----NFLK---------------------MAMVAKEEEINSLMQSIH 994
Cdd:TIGR02169  528 AQLGSVGERYATaievaagnRLNNVVVEDDAVakeaiELLKrrkagratflplnkmrderrdLSILSEDGVIGFAVDLVE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  995 SGEEKASAF----------QDLQEKRHEEQKQAISTLE---------------IRLSDAHRLLEEKASSIEMQtSQVMQL 1049
Cdd:TIGR02169  608 FDPKYEPAFkyvfgdtlvvEDIEAARRLMGKYRMVTLEgelfeksgamtggsrAPRGGILFSRSEPAELQRLR-ERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1050 QRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEER 1129
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1130 IAQLQARLGtasalasekdsQLELLHAELKERDSlRIQAAEMEARHKELEESIAQLQARLgtASALASEKDSQLELLHAE 1209
Cdd:TIGR02169  767 IEELEEDLH-----------KLEEALNDLEARLS-HSRIPEIQAELSKLEEEVSRIEARL--REIEQKLNRLTLEKEYLE 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1210 lKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAEL----KERDGLRIQAAEMEARHKELEES 1285
Cdd:TIGR02169  833 -KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdlkKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1286 IAQLQARLGTASALASGKQSELDLLHKEVREREKL--RIRAVEVEEAQHKELEERVT---EASTLASERKSQLDSLHNEM 1360
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeEELSLEDVQAELQRVEEEIRalePVNMLAIQEYEEVLKRLDEL 991

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 1338812033 1361 NEKDHVIKTQHMELESTVTQLKEQLHTAtsLAAVQKRVNEKLNEDIRRL 1409
Cdd:TIGR02169  992 KEKRAKLEEERKAILERIEEYEKKKREV--FMEAFEAINENFNEIFAEL 1038
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 222-1022 1.77e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 89.74  E-value: 1.77e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  222 EREMRDELErELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQpKEIEQLQRKNEGLLtrlhdVLKQCQELKTNKTQ 301
Cdd:TIGR02169  169 DRKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  302 MERKIDDLTEENGILSVQMREIFSRLSSAE----AAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLNEQIQILQ 377
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEqlleELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  378 GKISILEDELSKAKAETlgggevmgpimewERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLE 457
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEI-------------EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  458 ELVSELNKmLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQ 537
Cdd:TIGR02169  389 DYREKLEK-LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  538 ERFAQKTIQELHERVDHLgSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETIS---------RERDAIATE---- 604
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKEL-SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHgtvaqlgsvGERYATAIEvaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  605 --YQHFQQEKEEVAcklNQQIVLLEEQQ------------SVEWSLLSELRKEKQ--------ELEQK------------ 650
Cdd:TIGR02169  547 nrLNNVVVEDDAVA---KEAIELLKRRKagratflplnkmRDERRDLSILSEDGVigfavdlvEFDPKyepafkyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  651 --VSSIEA---IVDNLR-------------------TRCHGLELDSEAQRASHQE----------EVESLKRKLHEAESI 696
Cdd:TIGR02169  624 lvVEDIEAarrLMGKYRmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRlrerleglkrELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  697 LGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQH 776
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  777 LGQQLSkvQQEKMRVDASMAKLIEEGREVErGLTAARDQAfltIKEREAETSKLRSEAEALSSKVILAEEAKAiELAKKD 856
Cdd:TIGR02169  784 LEARLS--HSRIPEIQAELSKLEEEVSRIE-ARLREIEQK---LNRLTLEKEYLEKEIQELQEQRIDLKEQIK-SIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  857 DEMQVLSKEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKaf 936
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS-- 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  937 clhekvereELQRQLKQEEdrclmykqEIVVKDKEVNFLKMAMVAKEEEINSL----MQSIHSGEEKASAFQDLQEKRHE 1012
Cdd:TIGR02169  935 ---------EIEDPKGEDE--------EIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVLKRLDELKEKRAK 997

                          890
                   ....*....|
gi 1338812033 1013 EQKQAISTLE 1022
Cdd:TIGR02169  998 LEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 901-1629 1.22e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 1.22e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  901 LRFQMNELEESANQKETEIEvLQTKLSNKDEELKAFCLHEKV-EREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAM 979
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKE-LKAELRELELALLVLRLEELReELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  980 VAKEEEINslmqsihsgeEKASAFQDLQEK--RHEEQKQAISTleiRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQ 1057
Cdd:TIGR02168  277 SELEEEIE----------ELQKELYALANEisRLEQQKQILRE---RLANLERQLEELEAQLEELESKLDELAEELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1058 ERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARL 1137
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1138 GTASALASEKdsQLELLHAEL----KERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLhaelker 1213
Cdd:TIGR02168  424 EELLKKLEEA--ELKELQAELeeleEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL------- 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1214 dslriqaAEMEARHKELEESIAQL---QAQLGTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQ 1290
Cdd:TIGR02168  495 -------ERLQENLEGFSEGVKALlknQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1291 ARLGTASALasgkqsELDLL-HKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQL---DSLHNEMNekdhv 1366
Cdd:TIGR02168  568 NELGRVTFL------PLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALE----- 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1367 IKTQHMELESTVTQLKEQLHTATSLA-AVQKRVNEKLNEDIRRLDVVRQ-ESMERDA--LRIRAIEAEDlKRKEMEETIV 1442
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITgGSAKTNSSILERRREIEELEEKiEELEEKIaeLEKALAELRK-ELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1443 KLKSEILTHTTKLEHLNKwhqqQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLplqECKAENE 1522
Cdd:TIGR02168  716 QLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE---AEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1523 RLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSE 1602
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1338812033 1603 KDLALKVNSLQAQVDY--------------ADRQLREYAKH 1629
Cdd:TIGR02168  869 EELESELEALLNERASleealallrseleeLSEELRELESK 909
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 294-953 7.39e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 7.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  294 ELKTNKTQMERKIDDlTEENgILSVQ--MREIFSRLSS----AEAAV--QKLSAEQESSQVEW--------ESKRGLLES 357
Cdd:COG1196    169 KYKERKEEAERKLEA-TEEN-LERLEdiLGELERQLEPlerqAEKAEryRELKEELKELEAELlllklrelEAELEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  358 ELGQALSQKEYLNEQIQILQGKISILEDELSKAKAE-TLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKK 436
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELElEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  437 EIemmyevektkfeaekarleelvselnkmltvqrgerEALEQALREQRVSLEAQIEALTADIASLTEAVQQrelavtnf 516
Cdd:COG1196    327 EL------------------------------------EEELEELEEELEELEEELEEAEEELEEAEAELAE-------- 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  517 sqkvdVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLgsVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISR 596
Cdd:COG1196    363 -----AEEALLEAEAELAEAEEELEELAEELLEALRAAA--ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  597 ERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRtrchGLELDSEAQR 676
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEGFLEGVK 511

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  677 ASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLrdeleverskhKETLAAKLQSKSQM 756
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-----------KAAKAGRATFLPLD 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  757 MEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARDQAflTIKEREAETSKLRSEAEA 836
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV--TLAGRLREVTLEGEGGSA 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  837 LSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELgtvkKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKE 916
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL----EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1338812033  917 TEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQ 953
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 654-1292 1.11e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  654 IEAIVDNLRTRCHGLELDSE-AQRAshQEEVESLKRKlhEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLR 732
Cdd:COG1196    191 LEDILGELERQLEPLERQAEkAERY--RELKEELKEL--EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  733 DELEVERSKHKEtLAAKLQSKSQMMEEMRELEEKTQNmsvEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAA 812
Cdd:COG1196    267 AELEELRLELEE-LELELEEAQAEEYELLAELARLEQ---DIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  813 RDQAFLTIKEREAETSKLRSEAEALSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQSSIE 892
Cdd:COG1196    343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  893 KRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEiVVKDKEV 972
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  973 NFLKMAMVAKEEEINSLMQSIHS----------------GEEKASAFQDLQEKRHEEQKQAISTL-EIRLSDAHRLLEEK 1035
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAGavavligveaayeaalEAALAAALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDK 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1036 ASSIEMQTSQVMQLQRDLstEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQ 1115
Cdd:COG1196    582 IRARAALAAALARGAIGA--AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1116 VAETETLHNKSEERIAQLQARLGTASALASEKdsQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASAL 1195
Cdd:COG1196    660 GSLTGGSRRELLAALLEAEAELEELAERLAEE--ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1196 ASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLqaqlGTASVLASEKdsqleslHAELKERdglriqAAEM 1275
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL----GPVNLLAIEE-------YEELEER------YDFL 800

                          650
                   ....*....|....*..
gi 1338812033 1276 EARHKELEESIAQLQAR 1292
Cdd:COG1196    801 SEQREDLEEARETLEEA 817
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 209-807 1.29e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.29e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  209 QFRLRKLQKQLVQERemRDELERELASRSQVITEREMQVSQLQhrvqrmmrdsEEQEQQPKEIEQLQRKNEGLLTRLHDV 288
Cdd:COG1196    219 KEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELE----------AELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  289 LKQCQELKTNKTQMERKIDDLTEengilsvqmreifsRLSSAEAAVQKLSAEQEssqvEWESKRGLLESELGQALSQKEY 368
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEE--------------RRRELEERLEELEEELA----ELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  369 LNEQIQILQGKISILEDELSKAKAETLGGGEvmgpimEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIemmyevektk 448
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEE------ELEELAEELLEALRAAAELAAQLEELEEAEEAL---------- 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  449 fEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVD--VERKR 526
Cdd:COG1196    413 -LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEelAEAAA 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  527 VEKLTEEMEKQERFAQKTIQELHE-----RVDHLGSVLNSKEEEARSNAEEW--ARERHEISRQQEVLMEARETISRERD 599
Cdd:COG1196    492 RLLLLLEAEADYEGFLEGVKAALLlaglrGLAGAVAVLIGVEAAYEAALEAAlaAALQNIVVEDDEVAAAAIEYLKAAKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  600 AIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQRASH 679
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  680 QEEVESLkrklhEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEE 759
Cdd:COG1196    652 EGEGGSA-----GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1338812033  760 MRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVER 807
Cdd:COG1196    727 EEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 524-1188 1.67e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.67e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  524 RKRVEKLTEEMEKQERFaqktiQELhervdhlgsvlnsKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIAT 603
Cdd:COG1196    199 ERQLEPLERQAEKAERY-----REL-------------KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  604 EYQHFQQEKEEvackLNQQIVLLEEQqsvewslLSELRKEKQELEQKVSSIEAIVDNLRTRchglELDSEAQRASHQEEV 683
Cdd:COG1196    261 ELAELEAELEE----LRLELEELELE-------LEEAQAEEYELLAELARLEQDIARLEER----RRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  684 ESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMREL 763
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  764 EEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAEALSSKVIL 843
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  844 AEEAKAIELAKKDDEMQVLSKEmKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQ---MNELEESANQKETEIE 920
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFL-EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAaalQNIVVEDDEVAAAAIE 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  921 VLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKA 1000
Cdd:COG1196    565 YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1001 SAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKAssIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLE 1080
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE--LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1081 KEALKNEVTSLQELAEKlkgELEELKREHENLRLQVAETETLHNKSEERIAQLQ---ARLGTASALASEKdsqlellHAE 1157
Cdd:COG1196    723 EEALEEQLEAEREELLE---ELLEEEELLEEEALEELPEPPDLEELERELERLEreiEALGPVNLLAIEE-------YEE 792

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1338812033 1158 LKERdslriqAAEMEARHKELEESIAQLQAR 1188
Cdd:COG1196    793 LEER------YDFLSEQREDLEEARETLEEA 817
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 777-1571 1.80e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 1.80e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  777 LGQQLSKVQQEKMRVDASMAkLIEEGREVERGLTAARDQAFLTIKER-EAETSKLRSEAEALSSKV------ILAEEAKA 849
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQA-LLKEKREYEGYELLKEKEALERQKEAiERQLASLEEELEKLTEEIselekrLEEIEQLL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  850 IELAKKDDEMQvlSKEMKQIQMELGtvkkakddmelDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNK 929
Cdd:TIGR02169  275 EELNKKIKDLG--EEEQLRVKEKIG-----------ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  930 DEELKAfclhEKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQEK 1009
Cdd:TIGR02169  342 EREIEE----ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1010 RHEEQ---KQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKN 1086
Cdd:TIGR02169  418 LSEELadlNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1087 EVTSLQELAEKLKGELEELKREHENLRLQVAEtetLHNKSEERIAQLQARLGT-ASALASEKDSQLELLHAELKERDSLR 1165
Cdd:TIGR02169  498 QARASEERVRGGRAVEEVLKASIQGVHGTVAQ---LGSVGERYATAIEVAAGNrLNNVVVEDDAVAKEAIELLKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1166 ---IQAAEMEARHKELeeSIAQLQARLGTASALAsEKDSQLE-----------------------------LLHAELKER 1213
Cdd:TIGR02169  575 atfLPLNKMRDERRDL--SILSEDGVIGFAVDLV-EFDPKYEpafkyvfgdtlvvedieaarrlmgkyrmvTLEGELFEK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1214 DSL----RIQAAEMEARHKELEESIAQLQAQLGtasvlasEKDSQLESLHAEL----KERDGLRIQAAEMEARHKELEES 1285
Cdd:TIGR02169  652 SGAmtggSRAPRGGILFSRSEPAELQRLRERLE-------GLKRELSSLQSELrrieNRLDELSQELSDASRKIGEIEKE 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1286 IAQLQARLGTASALASGKQSELDLLHKEV----REREKLRIRAVEVEEAQHKELEErvtEASTLASERKSQLDSLHNEMN 1361
Cdd:TIGR02169  725 IEQLEQEEEKLKERLEELEEDLSSLEQEIenvkSELKELEARIEELEEDLHKLEEA---LNDLEARLSHSRIPEIQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1362 EkdhvIKTQHMELESTVTQLKEQLHTATSLaavqkrvNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETI 1441
Cdd:TIGR02169  802 K----LEEEVSRIEARLREIEQKLNRLTLE-------KEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1442 VKLKSEILTHTTKLEHLNK---WHQQQLSVLRNENQTLLSMKESmvKEQEVSQrvkvsLESKLKLAGQELSVLLPLQ--- 1515
Cdd:TIGR02169  871 EELEAALRDLESRLGDLKKerdELEAQLRELERKIEELEAQIEK--KRKRLSE-----LKAKLEALEEELSEIEDPKged 943

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1516 ECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLE 1571
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLE 999
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 213-539 2.58e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.58e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  213 RKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQC 292
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  293 QELKTNKTQM----ERKIDDLTEENGILSVQMREIFSRLSSAE-AAVQKLSAEQESSQVEWESKRGLLESELGQALSQKE 367
Cdd:TIGR02169  750 EQEIENVKSElkelEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  368 YLNEQIQILQGKISILED-ELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEvek 446
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEqIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE--- 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  447 tKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVS---------LEAQIEALTADIASLTE----AVQQRELAV 513
Cdd:TIGR02169  907 -ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIRALEPvnmlAIQEYEEVL 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1338812033  514 TNFS------QKVDVERKRVEKLTEEMEKQER 539
Cdd:TIGR02169  986 KRLDelkekrAKLEEERKAILERIEEYEKKKR 1017
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 766-1605 3.20e-14

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 78.94  E-value: 3.20e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  766 KTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLieegrEVERGLTAARDQAFLTIKEREAETSklrseaEALSSKVILAE 845
Cdd:TIGR00606  201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQL-----ESSREIVKSYENELDPLKNRLKEIE------HNLSKIMKLDN 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  846 EAKAIELAKKddEMQVLSKEMKQIQMEL--GTVKKAKDdMELDLQSSIEKRQEQLLVLRFQMNELEESA---NQKETEIE 920
Cdd:TIGR00606  270 EIKALKSRKK--QMEKDNSELELKMEKVfqGTDEQLND-LYHNHQRTVREKERELVDCQRELEKLNKERrllNQEKTELL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  921 VLQTKLSnkdeeLKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKA 1000
Cdd:TIGR00606  347 VEQGRLQ-----LQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKE 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1001 SAFQDLQEKRHEEQKQAISTLEIRlsdaHRLLEEKASSIEMQTSQVMQLQ----RDLSTEQERVVSLEQSMKVSDDALIH 1076
Cdd:TIGR00606  422 RLKQEQADEIRDEKKGLGRTIELK----KEILEKKQEELKFVIKELQQLEgssdRILELDQELRKAERELSKAEKNSLTE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1077 CKLEKE-ALKNEVTSLQELAEKLKGELEELKREHENLRlqvaETETLHNKSEERIAQLQARLGTASALASEKDSQLELLH 1155
Cdd:TIGR00606  498 TLKKEVkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT----QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKK 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1156 AELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIA 1235
Cdd:TIGR00606  574 QLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSK 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1236 QLqAQLGTASVLASEKDSQLES--------------LHAELKE-RDGLRIQAAEMEARHKELEESIAQLQARLGTASALA 1300
Cdd:TIGR00606  654 QR-AMLAGATAVYSQFITQLTDenqsccpvcqrvfqTEAELQEfISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1301 SGKQSELDLLHKEVRE-REKLRIRAVEVEEAQHkELEERVTEASTLASERKSQLDSLHNEMnekdhVIKTQHMELESTVT 1379
Cdd:TIGR00606  733 PGRQSIIDLKEKEIPElRNKLQKVNRDIQRLKN-DIEEQETLLGTIMPEEESAKVCLTDVT-----IMERFQMELKDVER 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1380 QLKEQLHTATS--LAAVQKRVNEKLNEDIRRLDVVRQESMERDALriraIEAEDLKRKEMEETIVKLKSEILTHTTKLEH 1457
Cdd:TIGR00606  807 KIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKL----IQDQQEQIQHLKSKTNELKSEKLQIGTNLQR 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1458 LNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQElsvllplQECKAENERLIGDLQEQLQAKTE 1537
Cdd:TIGR00606  883 RQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK-------ETSNKKAQDKVNDIKEKVKNIHG 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033 1538 AMKHCKAQVQmakthyNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSEKDL 1605
Cdd:TIGR00606  956 YMKDIENKIQ------DGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWL 1017
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1080-1303 4.15e-14

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 76.34  E-value: 4.15e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELK 1159
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1160 ErdslRIQAAEMEARHKELE-----ESIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESI 1234
Cdd:COG4942    108 E----LLRALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAE---LAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGK 1303
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAE---LAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-604 2.07e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLK 290
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 qcqelktnktqmerkidDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESkrglLESELGQALSQKEYLN 370
Cdd:TIGR02168  758 -----------------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA----LREALDELRAELTLLN 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  371 EQIQILQGKISILEDELSKAKAETLGGGEvmgpimEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFE 450
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEE------QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  451 AEKARLEELVSELNKMLTvQRGEREALEQALREQRVSLEAQIEALTADIASLTEAvqqrelavtnFSQKVDVERKRVEKL 530
Cdd:TIGR02168  891 LLRSELEELSEELRELES-KRSELRRELEELREKLAQLELRLEGLEVRIDNLQER----------LSEEYSLTLEEAEAL 959

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033  531 TEEMEKQERFAQKTIQELHERVDHLGSV-LNSKEEearsnAEEWARERHEISRQQEVLMEARETIS---RERDAIATE 604
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLENKIKELGPVnLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEeaiEEIDREARE 1032
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 201-1134 9.87e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.00  E-value: 9.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQLVQEREMRdELERELASRSQVITEREMQVSQLQhrvQRMMRDSEEQEQQPKEIEQLQRKNEG 280
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNELH-EKQKFYLRQSVIDLQTKLQEMQME---RDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  281 LLTRLHDVLKQcQELKTNKTQMERKIDDLTEENGILsvqmREIFSRLSSAEAAVQKLSAEQES-SQVEWESkrglleseL 359
Cdd:pfam15921  152 HELEAAKCLKE-DMLEDSNTQIEQLRKMMLSHEGVL----QEIRSILVDFEEASGKKIYEHDSmSTMHFRS--------L 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  360 GQALSQK-EYLNEQIQILQGKISILEDELSKAKAETLGGGEVMgpimewerlnqeiadlnhkLSQLQEIIIQLQKEkkei 438
Cdd:pfam15921  219 GSAISKIlRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL-------------------LQQHQDRIEQLISE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  439 emmYEVEKTKFeAEKArleelvselnkmltvqrgerealeQALREQRVSLEAQIEALTAdiaslteavQQRELAVTNFSQ 518
Cdd:pfam15921  276 ---HEVEITGL-TEKA------------------------SSARSQANSIQSQLEIIQE---------QARNQNSMYMRQ 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  519 KVDVErKRVEKLTEEMEKQERFAQKTIQELHERVdhlgSVLNSKEEEARSNAEEWARERHEISRQQEVLMEarETISRER 598
Cdd:pfam15921  319 LSDLE-STVSQLRSELREAKRMYEDKIEELEKQL----VLANSELTEARTERDQFSQESGNLDDQLQKLLA--DLHKREK 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  599 DaiateyqhFQQEKEEvacklNQQIVLLEEQQSVEwslLSELRKEKQELEQKVSSIEAIVDNLRTRCHGlelDSEAQRAS 678
Cdd:pfam15921  392 E--------LSLEKEQ-----NKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSECQG---QMERQMAA 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  679 HQEEVESLKRklheAESILGVYEGKLADHQKIVEEHIALRDELSAAaecakglrdelevERSKhkETLAAKLQSKSQMME 758
Cdd:pfam15921  453 IQGKNESLEK----VSSLTAQLESTKEMLRKVVEELTAKKMTLESS-------------ERTV--SDLTASLQEKERAIE 513

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  759 EMReleektqnmsvemqhlgqqlSKVQQEKMRVDASMaklieegrevergltaardQAFLTIKEREAETSKLRSEAEALs 838
Cdd:pfam15921  514 ATN--------------------AEITKLRSRVDLKL-------------------QELQHLKNEGDHLRNVQTECEAL- 553

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  839 sKVILAEEAKAIELAKKDDEmqvlskEMKQIQMELGTVKKAKDDMELDLQSSIEKRqeqllvlRFQMNELEESANQKETE 918
Cdd:pfam15921  554 -KLQMAEKDKVIEILRQQIE------NMTQLVGQHGRTAGAMQVEKAQLEKEINDR-------RLELQEFKILKDKKDAK 619

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  919 IEVLQTKLSNKDEElKAFCLHEKVEREELQRQLKQEEDRCLmykqeivvkdkevnflkmamvakeEEINSLMQSIHSGEE 998
Cdd:pfam15921  620 IRELEARVSDLELE-KVKLVNAGSERLRAVKDIKQERDQLL------------------------NEVKTSRNELNSLSE 674

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  999 KASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIE-MQTSQ------VMQLQRDLSTEQERVVSLEQSMKVSD 1071
Cdd:pfam15921  675 DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKsMEGSDghamkvAMGMQKQITAKRGQIDALQSKIQFLE 754

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1072 DALIHCKLEKEALKNEVTSL-QELA------EKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQ 1134
Cdd:pfam15921  755 EAMTNANKEKHFLKEEKNKLsQELStvatekNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 211-664 3.15e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELAsrsqvitEREMQVSQLQHRVQRMMRDSEEQEQQpkeIEQLQRKNEGLLTRLHDVLK 290
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELA-------EAEEELEELAEELLEALRAAAELAAQ---LEELEEAEEALLERLERLEE 421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQMERKIDDLTEENgilsVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLN 370
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  371 EQIQILQGKisiLEDELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEmmyEVEKTKFE 450
Cdd:COG1196    498 EAEADYEGF---LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAI---EYLKAAKA 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  451 AEKARLeelvsELNKMltvqrGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKL 530
Cdd:COG1196    572 GRATFL-----PLDKI-----RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT 641

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  531 TEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQ 610
Cdd:COG1196    642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1338812033  611 EKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTR 664
Cdd:COG1196    722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 211-825 7.11e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 7.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRmmrDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLK 290
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE---LKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGllesELGQALSQKEYLN 370
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----KLEQLAADLSKYE 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  371 EQIQILQGKISILEDELSKAK---AETLGGGEVMGPIMEWERLNQEIadLNHKLSQLQEIIIQLQKEKKEIEMMYEVekt 447
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQrelAEAEAQARASEERVRGGRAVEEV--LKASIQGVHGTVAQLGSVGERYATAIEV--- 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  448 kfeAEKARLEELVSE------------------------LNKMLTVQRGEREALEQALREQRVSL---EAQIEALTADIA 500
Cdd:TIGR02169  544 ---AAGNRLNNVVVEddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIGFAVDLvefDPKYEPAFKYVF 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  501 SLTEAVQQRELA---------VT-----------------------NFSQKVDVERKRVEKLTEEMEKQERFAQKTIQEL 548
Cdd:TIGR02169  621 GDTLVVEDIEAArrlmgkyrmVTlegelfeksgamtggsraprggiLFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  549 HERVDHLG---SVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVL 625
Cdd:TIGR02169  701 ENRLDELSqelSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  626 LEE-QQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLEL-----------------DSEAQRASHQEEVESLK 687
Cdd:TIGR02169  781 LNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeylekeiqelqeqriDLKEQIKSIEKEIENLN 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  688 RKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKE---TLAAKLQSKSQMMEEMRELE 764
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlsELKAKLEALEEELSEIEDPK 940

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033  765 EKTQNMSVEMQHLGqqlsKVQQEKMRVDASMAKL-------IEEGREVERGLTAARDQAFLTIKEREA 825
Cdd:TIGR02169  941 GEDEEIPEEELSLE----DVQAELQRVEEEIRALepvnmlaIQEYEEVLKRLDELKEKRAKLEEERKA 1004
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 804-1435 9.57e-12

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 70.64  E-value: 9.57e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  804 EVERGLTAARDQAFLTIKEREAETSKLRSEAEALSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDM 883
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  884 ELDLQSSIEKRQEQLLvlRFQMNELEESANQKETEIEVlQTKLSNKDEELKAFC-LHEKVEREELQRQLKQEEDRclmyK 962
Cdd:pfam12128  317 VAKDRSELEALEDQHG--AFLDADIETAAADQEQLPSW-QSELENLEERLKALTgKHQDVTAKYNRRRSKIKEQN----N 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  963 QEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQ-KQAISTLEIRLSDA----HRLLEEKAS 1037
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRlKSRLGELKLRLNQAtatpELLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1038 SIEMQTSQVMQLQRdlSTEQERVVS-LEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELkreHENLRLQV 1116
Cdd:pfam12128  470 DERIERAREEQEAA--NAEVERLQSeLRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTL---LHFLRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1117 AETEtlhnkseERIAQLqarlgTASALASEKDSQLELLHAELKERDSL--------RIQAAEMEARHKELEESIAQLQAR 1188
Cdd:pfam12128  545 PDWE-------QSIGKV-----ISPELLHRTDLDPEVWDGSVGGELNLygvkldlkRIDVPEWAASEEELRERLDKAEEA 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1189 LGTASALASEKDSQLELLHAELKE---------------RDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDS 1253
Cdd:pfam12128  613 LQSAREKQAAAEEQLVQANGELEKasreetfartalknaRLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLK 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1254 QLESLHAELKE--RDGLRIQAAEMEARHKELEESIAQLQARLGTA-SALASGKQSELDLLHKEV-REREKLRIRAVEVE- 1328
Cdd:pfam12128  693 QLDKKHQAWLEeqKEQKREARTEKQAYWQVVEGALDAQLALLKAAiAARRSGAKAELKALETWYkRDLASLGVDPDVIAk 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1329 -EAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLhtaTSLAAVQKRVNEKLNedir 1407
Cdd:pfam12128  773 lKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQL---ARLIADTKLRRAKLE---- 845

                          650       660
                   ....*....|....*....|....*...
gi 1338812033 1408 rldvvrqesMERDALRIRAIEAEDLKRK 1435
Cdd:pfam12128  846 ---------MERKASEKQQVRLSENLRG 864
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1796-1844 1.84e-11

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 61.07  E-value: 1.84e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1796 LLSLPGYRRSTTHS------HVPPRNINTYGVGA-ENEPDVTDDWKRIVELQARNK 1844
Cdd:cd22298      1 LLSLPGYRPSTRSStrrsqsSSATGGRSTFYMGTcQDEPEHLDDWNRIAELQQRNR 56
PTZ00121 PTZ00121
MAEBL; Provisional
 523-1232 3.77e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.77e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  523 ERKRVEKLTEEMEKQERFAQKTIQELHERvdhlgsvlNSKEEEARSNAEEwARERHEISRQQEV--LMEARETISRERDA 600
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEE--------ARKAEEAKKKAED-ARKAEEARKAEDArkAEEARKAEDAKRVE 1155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  601 IATEYQhfQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEkqeleQKVSSIEAI--VDNLRtRCHGLELDSEAQRAS 678
Cdd:PTZ00121  1156 IARKAE--DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKA-----EDARKAEAArkAEEER-KAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  679 HQEEVESLKRKLHEAESILGV-YEGKLADHQKIVEEHIALRDELSAAAECAKGlrDELEversKHKETLAAKLQSKSQMM 757
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEErNNEEIRKFEEARMAHFARRQAAIKAEEARKA--DELK----KAEEKKKADEAKKAEEK 1301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  758 EEMRELEEKTQnmsvEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVErgltAARDQAFLTIKEREAETSKLRSEAEAL 837
Cdd:PTZ00121  1302 KKADEAKKKAE----EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE----AAKAEAEAAADEAEAAEEKAEAAEKKK 1373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  838 SSKVILAEEAKA-IELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKE 916
Cdd:PTZ00121  1374 EEAKKKADAAKKkAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA 1453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  917 TEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIVVKD---------------KEVNFLKMAMVA 981
Cdd:PTZ00121  1454 EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeakkkadeakkaeeaKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  982 KEEEINSLMQSIHSGEE--KASAFQDLQEKRHEEQKQaisTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQrdlstEQER 1059
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADElkKAEELKKAEEKKKAEEAK---KAEEDKNMALRKAEEAKKAEEARIEEVMKLY-----EEEK 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1060 VVSLEQSMKVSDDALIHCKLEK-EALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETEtlhnKSEERIAQLQARLG 1138
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA----KKAEEDKKKAEEAK 1681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1139 TASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRI 1218
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH 1761

                          730
                   ....*....|....
gi 1338812033 1219 QAAEMEARHKELEE 1232
Cdd:PTZ00121  1762 LKKEEEKKAEEIRK 1775
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
201-723 4.33e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.53  E-value: 4.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQlVQEREMRD------ELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQL 274
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQ-IEEKEEKDlherlnGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  275 QRKNEglltrlhdvlkqcqELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSS--AEAAVQKLSAEQESSQVE-WESK 351
Cdd:PRK02224   257 EAEIE--------------DLRETIAETEREREELAEEVRDLRERLEELEEERDDllAEAGLDDADAEAVEARREeLEDR 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  352 RGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETlgggevmgpimewERLNQEIADLNHKLSQLQEIIIQL 431
Cdd:PRK02224   323 DEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA-------------AELESELEEAREAVEDRREEIEEL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  432 QKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKM---LTVQRGEREALEQALREQRVSLEA------------------ 490
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELrerEAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvet 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  491 ------QIEALTADIASLTEAVQQRELAVTNFSQKVDVERkRVEKLTEEMEK-QERFAQK---------TIQELHERVDH 554
Cdd:PRK02224   470 ieedreRVEELEAELEDLEEEVEEVEERLERAEDLVEAED-RIERLEERREDlEELIAERretieekreRAEELRERAAE 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  555 LGSVLNSKEE---EARSNAEEWARERHEISRQQEVLMEARETISRERDAIATeyqhfQQEKEEVACKLNQQIVLLEEQQS 631
Cdd:PRK02224   549 LEAEAEEKREaaaEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA-----IADAEDEIERLREKREALAELND 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  632 VEWSLLSELRKEKQELEQKVSsiEAIVDNLRTRchgleldsEAQRASHQEEVESLKRKLHEAESIL----GVYEGKLADH 707
Cdd:PRK02224   624 ERRERLAEKRERKRELEAEFD--EARIEEARED--------KERAEEYLEQVEEKLDELREERDDLqaeiGAVENELEEL 693

                          570
                   ....*....|....*.
gi 1338812033  708 QKIVEEHIALRDELSA 723
Cdd:PRK02224   694 EELRERREALENRVEA 709
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1084-1600 6.30e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 6.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1084 LKNEVTSLQELAEKLKGELEELKREHEN-----LRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAEL 1158
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 KERDSlriqaaeMEARH-KELEESIAQLQARLGTASALASEK----DSQLELLHAELKER---------------DSLRI 1218
Cdd:pfam15921  309 RNQNS-------MYMRQlSDLESTVSQLRSELREAKRMYEDKieelEKQLVLANSELTEArterdqfsqesgnldDQLQK 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKEL---EESIAQLQAQLGTASVLASEKDSQLESLHAELKERDGLrIQAAEMEARhKELEESIAQLQAR--- 1292
Cdd:pfam15921  382 LLADLHKREKELsleKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL-LKAMKSECQ-GQMERQMAAIQGKnes 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1293 LGTASALASGKQSELDLLHKEVREREKLRI--------------------RAVEVEEAQHKELEERV----TEASTLASE 1348
Cdd:pfam15921  460 LEKVSSLTAQLESTKEMLRKVVEELTAKKMtlessertvsdltaslqekeRAIEATNAEITKLRSRVdlklQELQHLKNE 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1349 R------KSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSL----AAVQKRVNE-------------KLNED 1405
Cdd:pfam15921  540 GdhlrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqvekAQLEKEINDrrlelqefkilkdKKDAK 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1406 IRRLDVvRQESMERDALRIRAIEAEDLKR-KEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQ----TLLSMK 1480
Cdd:pfam15921  620 IRELEA-RVSDLELEKVKLVNAGSERLRAvKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEemetTTNKLK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1481 ESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQL 1560
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL 778

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1338812033 1561 LEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKL 1600
Cdd:pfam15921  779 STVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASL 818
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 183-549 7.32e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.74  E-value: 7.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  183 EVQFLELKTVASSSVGSPIQDVLNTPQFRLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQhrvqrmmrdsE 262
Cdd:TIGR04523  294 KSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ----------R 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  263 EQEQQPKEIEQLQRKNEGLLTRLhdvlkqcQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQE 342
Cdd:TIGR04523  364 ELEEKQNEIEKLKKENQSYKQEI-------KNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETII 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  343 SSQVE---WESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAE-TLGGGEVMGPIMEWERLNQEIADLN 418
Cdd:TIGR04523  437 KNNSEikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElKSKEKELKKLNEEKKELEEKVKDLT 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  419 HKLSQLQEIIIQLQKEKKEIE-----MMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREqrvsLEAQIE 493
Cdd:TIGR04523  517 KKISSLKEKIEKLESEKKEKEskisdLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEE----KQELID 592

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033  494 ALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELH 549
Cdd:TIGR04523  593 QKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
820-1448 8.18e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 8.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  820 IKEREAETSKLRSEAEALSSKVILAEEAKAiELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMElDLQSSIEKRQEQLL 899
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEK-ELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  900 VLRFQMNELEESANQKETEIEVLQTKLsnkdEELKafclhEKVEREElqrQLKQEEDRCLMYKQEIVVKDKEVNFLKMAM 979
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEI----EELE-----EKVKELK---ELKEKAEEYIKLSEFYEEYLDELREIEKRL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  980 VAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAistleIRLSDAHRLLEEkassiemqtsqVMQLQRDLSteqer 1059
Cdd:PRK03918   317 SRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-----EELEERHELYEE-----------AKAKKEELE----- 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1060 vvsleqsmkvsddalihcKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGT 1139
Cdd:PRK03918   376 ------------------RLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGK 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1140 ASALASE--KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKD--SQLELLHAELKERDS 1215
Cdd:PRK03918   438 CPVCGREltEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNL 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1216 LRIQAAEMEARhkELEESIAQLQAqlgtasvlasekdsQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGT 1295
Cdd:PRK03918   518 EELEKKAEEYE--KLKEKLIKLKG--------------EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1296 ASALA----SGKQSELDLLHKE------VREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDH 1365
Cdd:PRK03918   582 LGFESveelEERLKELEPFYNEylelkdAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1366 V-IKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIrrldvvrqESMERDALRIRAIEAEDLKRKEMEETIVKL 1444
Cdd:PRK03918   662 EeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL--------EEREKAKKELEKLEKALERVEELREKVKKY 733


                   ....
gi 1338812033 1445 KSEI 1448
Cdd:PRK03918   734 KALL 737
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1087-1316 9.81e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 67.25  E-value: 9.81e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1087 EVTSLQELAEKLKGELEELKREHENLRLQVAETETLhnkseERIAQLQARLGTASALASEKDSQLELLHAELKERdslri 1166
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIELL-----EPIRELAERYAAARERLAELEYLRAALRLWFAQR----- 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1167 QAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQaaemearhkELEESIAQLQAQLGTASV 1246
Cdd:COG4913    289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE---------QLEREIERLERELEERER 359

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1247 LASEKDSQLESLHAELK-ERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVRE 1316
Cdd:COG4913    360 RRARLEALLAALGLPLPaSAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
886-1359 1.08e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.99  E-value: 1.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  886 DLQSSIEKRQEQLLVLRfqMNELEESANQKETEIEVLQTKLSNKDEElkafclhekveREELQRQLKQEEDRclmyKQEI 965
Cdd:PRK02224   191 QLKAQIEEKEEKDLHER--LNGLESELAELDEEIERYEEQREQARET-----------RDEADEVLEEHEER----REEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  966 VVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQD----------LQEKRHEEQKQAISTLEIRLSDAHRLLEEK 1035
Cdd:PRK02224   254 ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEerddllaeagLDDADAEAVEARREELEDRDEELRDRLEEC 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1036 ASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAE--------------KLKGE 1101
Cdd:PRK02224   334 RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEelrerfgdapvdlgNAEDF 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1102 LEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTAS--------------ALASEKDSQLELLHAELKErdsLRIQ 1167
Cdd:PRK02224   414 LEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvETIEEDRERVEELEAELED---LEEE 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1168 AAEMEARH---KELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTA 1244
Cdd:PRK02224   491 VEEVEERLeraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEA 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1245 SVLASEKDSQLESLHAELKERDGLRIQAAEMEarhkELEESIAQLQARLGTASALASGKQSELDLLHKEVRE-REKLRIR 1323
Cdd:PRK02224   571 REEVAELNSKLAELKERIESLERIRTLLAAIA----DAEDEIERLREKREALAELNDERRERLAEKRERKRElEAEFDEA 646

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1338812033 1324 AVEVEEAQHKELEERVTEASTLASERKSQLDSLHNE 1359
Cdd:PRK02224   647 RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 891-1658 3.49e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 65.76  E-value: 3.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  891 IEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEElkafclhekvEREELQRQLKQEEDRCLMYKQEIVVKDK 970
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKAL----------EYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  971 EVNFLKMAMvAKEEEINSLMQSIHSGEEKAsafqDLQEKRHEEQKQAISTLEirlsdahRLLEEKASSIEMQTSQVMQLQ 1050
Cdd:pfam02463  239 IDLLQELLR-DEQEEIESSKQEIEKEEEKL----AQVLKENKEEEKEKKLQE-------EELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1051 RDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERI 1130
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1131 AQLQARLGTASALASE-KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAE 1209
Cdd:pfam02463  387 SSAAKLKEEELELKSEeEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1210 LKeRDSLRIQAAEMEARHKELEEsiaqlqaqlgtasvlASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQL 1289
Cdd:pfam02463  467 LK-KSEDLLKETQLVKLQEQLEL---------------LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1290 QARLGTASALASGKqseldllhKEVREREKLRIRAVEVEEAQHKELEERVteasTLASERKSQLDSLHNEMNEKDHVIKt 1369
Cdd:pfam02463  531 LGDLGVAVENYKVA--------ISTAVIVEVSATADEVEERQKLVRALTE----LPLGARKLRLLIPKLKLPLKSIAVL- 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1370 qhmeleSTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEIL 1449
Cdd:pfam02463  598 ------EIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1450 THTTKLEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENERLigdlq 1529
Cdd:pfam02463  672 TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID----- 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1530 eQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSEKDLALKV 1609
Cdd:pfam02463  747 -EEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE 825

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 1338812033 1610 NSLQAQVDYADRQLREYAKHGIDTTLNTCKPPSQEERSEKLADLSKDSL 1658
Cdd:pfam02463  826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLL 874
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 510-1407 5.86e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 5.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  510 ELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVdhlgsvlnskeeearsnaeewarerheisrqQEVLMe 589
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKL-------------------------------QEMQM- 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  590 aretisrERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLE 669
Cdd:pfam15921  125 -------ERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFE 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  670 ldseaqrashqeevESLKRKLHEAESILGVYEGKLADH-QKIVEEhiaLRDELSAAAECAKGLRDELEVERSKHKETLAA 748
Cdd:pfam15921  198 --------------EASGKKIYEHDSMSTMHFRSLGSAiSKILRE---LDTEISYLKGRIFPVEDQLEALKSESQNKIEL 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  749 KLQSKSQMMEEMRELEEktqnmsVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREvergltaARDQAFLTIKEREAETS 828
Cdd:pfam15921  261 LLQQHQDRIEQLISEHE------VEITGLTEKASSARSQANSIQSQLEIIQEQARN-------QNSMYMRQLSDLESTVS 327

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  829 KLRSEAEALSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELGTVkkakDDMELDLQSSIEKRQEQLLVLRFQMNEL 908
Cdd:pfam15921  328 QLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL----DDQLQKLLADLHKREKELSLEKEQNKRL 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  909 EESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQeedrclmykQEIVVKDKEVNFlkmamvakeEEINS 988
Cdd:pfam15921  404 WDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMER---------QMAAIQGKNESL---------EKVSS 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  989 LMQSIHSGEEK-ASAFQDLQEKrheeqKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVvsleQSM 1067
Cdd:pfam15921  466 LTAQLESTKEMlRKVVEELTAK-----KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQEL----QHL 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1068 KVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELE---------------------ELKREHENLRLQVAETETLHNKS 1126
Cdd:pfam15921  537 KNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEnmtqlvgqhgrtagamqvekaQLEKEINDRRLELQEFKILKDKK 616

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1127 EERIAQLQARLgtasalasekdSQLELLHAELKERDSLRIQAAemearhKELEESIAQLQARLGTASALASEKDSQLELL 1206
Cdd:pfam15921  617 DAKIRELEARV-----------SDLELEKVKLVNAGSERLRAV------KDIKQERDQLLNEVKTSRNELNSLSEDYEVL 679

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1207 HAELKERDslriqaaemearhKELEESIAQLQAQLGTASvlasekdSQLESLHAELKERDGLRIQAAEMEARHKEleesi 1286
Cdd:pfam15921  680 KRNFRNKS-------------EEMETTTNKLKMQLKSAQ-------SELEQTRNTLKSMEGSDGHAMKVAMGMQK----- 734

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1287 aQLQARLGTASALASGKQSELDLLHKEVREREKLRiraveveeaqhKELEERVTEASTLASERksqldslhNEMNEKDHV 1366
Cdd:pfam15921  735 -QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLK-----------EEKNKLSQELSTVATEK--------NKMAGELEV 794

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 1338812033 1367 IKTQHMELESTVTQLKEQLHTAT-SLAAVQKRVNEKLNEDIR 1407
Cdd:pfam15921  795 LRSQERRLKEKVANMEVALDKASlQFAECQDIIQRQEQESVR 836
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 854-1370 5.97e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.66  E-value: 5.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  854 KKDDEMQVLSKEMKQIQMELGTVK---KAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKd 930
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLteiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKL- 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  931 eELKAFCLHEKVER-EELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQ---DL 1006
Cdd:TIGR04523  200 -ELLLSNLKKKIQKnKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQkelEQ 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1007 QEKRHEEQKQAISTLEIRLSD-----AHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEK 1081
Cdd:TIGR04523  279 NNKKIKELEKQLNQLKSEISDlnnqkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESEN 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1082 EALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAEL--- 1158
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIikn 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 -KERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKER----DSLRIQAAEMEARHKELEES 1233
Cdd:TIGR04523  439 nSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKekelKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1234 IAQLQAQLGTASVLASEKDSQLESLHAELKE------RDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSEL 1307
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDLEDELNKddfelkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEK 598

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1308 DLLHKEVREREKLRI---RAVEVEEAQHKELEervteastlasERKSQLDSLHNEMNEKDHVIKTQ 1370
Cdd:TIGR04523  599 KDLIKEIEEKEKKISsleKELEKAKKENEKLS-----------SIIKNIKSKKNKLKQEVKQIKET 653
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1082-1352 6.14e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.94  E-value: 6.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1082 EALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKS---------EERIAQLQARLgtASALASEKD---- 1148
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSwdeidvasaEREIAELEAEL--ERLDASSDDlaal 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1149 -SQLELLHAEL----KERDSLRIQAAEMEARHKELEESIAQLQARLGTASALAS-EKDSQLELLHAELKERDSLRIQAAE 1222
Cdd:COG4913    691 eEQLEELEAELeeleEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlELRALLEERFAAALGDAVERELREN 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1223 MEARHKELEESIAQLQAQLGTA--------SVLASEKDSQLES------LHAELKERDGLRIQAAEMEARHKELEESIAQ 1288
Cdd:COG4913    771 LEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLESlpeylaLLDRLEEDGLPEYEERFKELLNENSIEFVAD 850

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338812033 1289 LQARLgtASALASGKQsELDLLHKEVRERE-------KLRIRAVEVEEAQH--KELEErVTEASTLASERKSQ 1352
Cdd:COG4913    851 LLSKL--RRAIREIKE-RIDPLNDSLKRIPfgpgrylRLEARPRPDPEVREfrQELRA-VTSGASLFDEELSE 919
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 981-1699 6.35e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 6.35e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  981 AKEEEINSLMQSIHSGEEKASAFQDLQEkrhEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERV 1060
Cdd:TIGR02169  191 LIIDEKRQQLERLRREREKAERYQALLK---EKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1061 VSLEQSMKvSDDALIHCKLEKE--ALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLG 1138
Cdd:TIGR02169  268 EEIEQLLE-ELNKKIKDLGEEEqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1139 TasaLASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLgtaSALASEKDSQLELLHAELKERDSLRI 1218
Cdd:TIGR02169  347 E---ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL---EKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELK--ERDGLRIQA--AEMEARHKELEESIAQLQARLG 1294
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSkyEQELYDLKEeyDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1295 TASALASGKQSELDLLHK-------------EVREREKL--------RIRAVEVEEaqhkelEERVTEASTLASERKS-- 1351
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKAsiqgvhgtvaqlgSVGERYATaievaagnRLNNVVVED------DAVAKEAIELLKRRKAgr 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1352 ----QLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERD------- 1420
Cdd:TIGR02169  575 atflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGElfeksga 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1421 -----------ALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEV 1489
Cdd:TIGR02169  655 mtggsraprggILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1490 SQRVKVSLESKLKLAGQELsvlLPLQECKAENERLIGDLQEQLQAKTEAMKHCKA-----QVQMAKTHYNGKKQQLLEVQ 1564
Cdd:TIGR02169  735 LKERLEELEEDLSSLEQEI---ENVKSELKELEARIEELEEDLHKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1565 EKAQTLENTLESRDQEVKVLRSEMKLLQ----------------IELDQAKLSE------------KDLALKVNSLQAQV 1616
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQeqridlkeqiksiekeIENLNGKKEEleeeleeleaalRDLESRLGDLKKER 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1617 DYADRQLREyAKHGIDTTlntckpPSQEERSEKLADLSKDSLDfCLDDSLSATRKPLAHEESSTPLVRSSERLRAKRRAL 1696
Cdd:TIGR02169  892 DELEAQLRE-LERKIEEL------EAQIEKKRKRLSELKAKLE-ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRV 963


                   ...
gi 1338812033 1697 GDD 1699
Cdd:TIGR02169  964 EEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1203-1538 9.28e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 9.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1203 LELLHAELKER-DSLRIQA--AEmeaRHKELEESIAQLQAQLGTAsvlasekdsQLESLHAELKErdgLRIQAAEMEARH 1279
Cdd:COG1196    191 LEDILGELERQlEPLERQAekAE---RYRELKEELKELEAELLLL---------KLRELEAELEE---LEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1280 KELEESIAQLQARLGTASAlasgKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEAstlaserKSQLDSLHNE 1359
Cdd:COG1196    256 EELEAELAELEAELEELRL----ELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL-------EERLEELEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1360 MNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESME---RDALRIRAIEAEDLKRKE 1436
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEElaeELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1437 MEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQE 1516
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340
                   ....*....|....*....|..
gi 1338812033 1517 cKAENERLIGDLQEQLQAKTEA 1538
Cdd:COG1196    485 -ELAEAAARLLLLLEAEADYEG 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1081-1439 1.06e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.92  E-value: 1.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1081 KEALKNEVTSLQELaEKLKGELEELKREHENLRLQVAETETLHNKSEErIAQLQARLGTASalasekdsqlelLHAELKE 1160
Cdd:TIGR02168  175 KETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAE-LRELELALLVLR------------LEELREE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1161 RDSLRIQAAEMEARHKELEESIAQLQARLgtasalasekdsqlellhaelkerdslriqaAEMEARHKELEESIAQLQAQ 1240
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKL-------------------------------EELRLEVSELEEEIEELQKE 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1241 LGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKL 1320
Cdd:TIGR02168  290 LYALANEISRLEQQKQILRERLAN---LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1321 RiravEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEkdhvIKTQHMELESTVTQLKEQLhtatsLAAVQKRVNE 1400
Cdd:TIGR02168  367 L----EELESRLEELEEQLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEI-----EELLKKLEEA 433

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1338812033 1401 KLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEE 1439
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
PTZ00121 PTZ00121
MAEBL; Provisional
 876-1613 1.52e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  876 VKKAKDDMELDLQSSIEKRQEQllvlRFQMNELEESaNQKETEIEVLQTKLSNKDEEL-KAFCLHEKVEREELQRQLKQE 954
Cdd:PTZ00121  1041 VLKEKDIIDEDIDGNHEGKAEA----KAHVGQDEGL-KPSYKDFDFDAKEDNRADEATeEAFGKAEEAKKTETGKAEEAR 1115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  955 EDRCLMYKQEIVVKDKEVNflkmamvaKEEEINSLMQSIHSGEEKASAFQDLQE--KRHEEQKQAistLEIRLSDAHRLL 1032
Cdd:PTZ00121  1116 KAEEAKKKAEDARKAEEAR--------KAEDARKAEEARKAEDAKRVEIARKAEdaRKAEEARKA---EDAKKAEAARKA 1184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1033 EEKASSIEMQTSQ-VMQLQRDLSTEQERvvSLEQSMKVSDDAlihcKLEKEALKNEVTSLQELAEKLKGE-LEELKREHE 1110
Cdd:PTZ00121  1185 EEVRKAEELRKAEdARKAEAARKAEEER--KAEEARKAEDAK----KAEAVKKAEEAKKDAEEAKKAEEErNNEEIRKFE 1258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1111 NLRLQVAETETLHNKSEEriaqlqARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLG 1190
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEE------ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD 1332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1191 TASALASEKDSQLELLHAElKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKERDGLRI 1270
Cdd:PTZ00121  1333 AAKKKAEEAKKAAEAAKAE-AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK 1411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1271 QAAEMEARHKELEESIAQL-QARLGTASALASGKQSELDLLHKEVREREKLRIRAVE---VEEAQHKELEER-VTEASTL 1345
Cdd:PTZ00121  1412 KAAAAKKKADEAKKKAEEKkKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakkADEAKKKAEEAKkADEAKKK 1491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1346 ASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEqlhtatslaAVQKRVNEKLN--EDIRRLDVVRQESMERDALR 1423
Cdd:PTZ00121  1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK---------AEEAKKADEAKkaEEKKKADELKKAEELKKAEE 1562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1424 IRaiEAEDLKRKEMEETIVKLKSEILTHTTKlEHLNKWHQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKL 1503
Cdd:PTZ00121  1563 KK--KAEEAKKAEEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK 1639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1504 AGQELSVLLPLQECKAENERLIGdlQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLESRDQEVKV 1583
Cdd:PTZ00121  1640 KKEAEEKKKAEELKKAEEENKIK--AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                          730       740       750
                   ....*....|....*....|....*....|...
gi 1338812033 1584 ---LRSEMKLLQIELDQAKLSEKDLALKVNSLQ 1613
Cdd:PTZ00121  1718 aeeLKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
904-1348 1.75e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.86  E-value: 1.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  904 QMNELEESANQKETEIEVLQTKLSNKDEelkafcLHEKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKE 983
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEE------LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  984 EEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSL 1063
Cdd:COG4717    146 ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1064 EQSMKVSDDALIHCKLEKEALKNEVT---------------SLQELAEKLKG-----------ELEELKREHENLRLQVA 1117
Cdd:COG4717    226 EEELEQLENELEAAALEERLKEARLLlliaaallallglggSLLSLILTIAGvlflvlgllalLFLLLAREKASLGKEAE 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1118 ETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHK--ELEESIAQLQARLGTASal 1195
Cdd:COG4717    306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQleELEQEIAALLAEAGVED-- 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1196 asekDSQLELLHAELKERDSLRiqaaemearhKELEESIAQLQAQLGTASVLASEKDsqLESLHAELKErdgLRIQAAEM 1275
Cdd:COG4717    384 ----EEELRAALEQAEEYQELK----------EELEELEEQLEELLGELEELLEALD--EEELEEELEE---LEEELEEL 444

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033 1276 EARHKELEESIAQLQARL------GTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASE 1348
Cdd:COG4717    445 EEELEELREELAELEAELeqleedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERASE 523
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 639-1367 3.46e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.55  E-value: 3.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  639 ELRKEKQELEQKVSSIEAIVDNLRTrCHGLELDSEAQRASHQEEVESLKRKLHEaesilgvyegKLADHQKIVEEHIA-L 717
Cdd:pfam12128  238 KIRPEFTKLQQEFNTLESAELRLSH-LHFGYKSDETLIASRQEERQETSAELNQ----------LLRTLDDQWKEKRDeL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  718 RDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAK 797
Cdd:pfam12128  307 NGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  798 -------LIEEGRE-----VERGLTAARDqafltikEREAETSKLRSEAEAlsSKVILAEEAKAIELAKKDDEMQVLSke 865
Cdd:pfam12128  387 qnnrdiaGIKDKLAkireaRDRQLAVAED-------DLQALESELREQLEA--GKLEFNEEEYRLKSRLGELKLRLNQ-- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  866 mKQIQMELGTVKKAKDDMeldlqssIEKRQEQLLvlrfQMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVERE 945
Cdd:pfam12128  456 -ATATPELLLQLENFDER-------IERAREEQE----AANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALD 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  946 ELQRQLKQEEDRCLMY--KQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQ-DLQEKRHEEQKQAISTLE 1022
Cdd:pfam12128  524 ELELQLFPQAGTLLHFlrKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKlDLKRIDVPEWAASEEELR 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1023 IRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVT--------SLQEL 1094
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNkalaerkdSANER 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1095 AEKLKGELEELKREHenlrlQVAETETLHNKSEERIAQLQARLgtasALASEKDSQLELLHAELkerDSLRIQAAemeAR 1174
Cdd:pfam12128  684 LNSLEAQLKQLDKKH-----QAWLEEQKEQKREARTEKQAYWQ----VVEGALDAQLALLKAAI---AARRSGAK---AE 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1175 HKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEA--RHKELEESIAqLQAQLGTASVLASEKD 1252
Cdd:pfam12128  749 LKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDwyQETWLQRRPR-LATQLSNIERAISELQ 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1253 SQLESLHAELKerdgLRIQAAEM-----EARHKELEESIAQL---QARLGTASALASGKQSELDLLHKEVREREKLRIRA 1324
Cdd:pfam12128  828 QQLARLIADTK----LRRAKLEMerkasEKQQVRLSENLRGLrceMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRD 903

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1338812033 1325 VEVEEAQhKELEERVTeasTLASERKSQLDSLHNEMNEKDHVI 1367
Cdd:pfam12128  904 YLSESVK-KYVEHFKN---VIADHSGSGLAETWESLREEDHYQ 942
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
212-696 3.80e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.00  E-value: 3.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  212 LRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQ---------------- 275
Cdd:PRK03918   226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyiklsefyeey 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  276 ----RKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESK 351
Cdd:PRK03918   306 ldelREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  352 RGLLESELGQALSQKEYLNEQIQILQGKISILE----------DELSKAKAETLGGGEvmgPIMEWERLN------QEIA 415
Cdd:PRK03918   386 PEKLEKELEELEKAKEEIEEEISKITARIGELKkeikelkkaiEELKKAKGKCPVCGR---ELTEEHRKElleeytAELK 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  416 DLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKA--RLEELVSELNKmLTVQRGEREALE-QALREQRVSLEAQI 492
Cdd:PRK03918   463 RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELaeQLKELEEKLKK-YNLEELEKKAEEyEKLKEKLIKLKGEI 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  493 EALTADIASLTEAVQQRELavtnfsqkVDVERKRVEKLTEEMEKQ-ERFAQKTIQELHERVDHLGSVLNsKEEEARSNAE 571
Cdd:PRK03918   542 KSLKKELEKLEELKKKLAE--------LEKKLDELEEELAELLKElEELGFESVEELEERLKELEPFYN-EYLELKDAEK 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  572 EWARERHEISRQQEVLMEARETISRERDAIateyQHFQQEKEEVACKLNQQIVLLEEQQSVEWS-LLSELRKEKQELEQK 650
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAFEELAETEKRL----EELRKELEELEKKYSEEEYEELREEYLELSrELAGLRAELEELEKR 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1338812033  651 VSSIEAIVDNLRTRchgleldsEAQRASHQEEVESLKRKLHEAESI 696
Cdd:PRK03918   689 REEIKKTLEKLKEE--------LEEREKAKKELEKLEKALERVEEL 726
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
637-1331 5.43e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.85  E-value: 5.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  637 LSELRKEKQELEQKVSSIEAIVDnlrtrcHGLELDSEAQRASHQEEVESlKRKLHEAESILGVYEGKLADHQKIVEEHIA 716
Cdd:COG4913    237 LERAHEALEDAREQIELLEPIRE------LAERYAAARERLAELEYLRA-ALRLWFAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  717 LRDELSAAAECAKGLRDELEVERSKH----KETLAAKLQSKSQMMEEMRELEEKTQNMsveMQHLGQQLSKVQQEKMRVD 792
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNggdrLEQLEREIERLERELEERERRRARLEAL---LAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  793 ASMAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAEALSS-------KVILAEEAKAIELAKKDDEMQVLSke 865
Cdd:COG4913    387 AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDALAEALGLDEAELPFVG-- 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  866 mkqiqmELGTVKKAkddmELDLQSSIEK-----------------------RQEQL-LVLRFQ-MNELEESANQKETEIE 920
Cdd:COG4913    465 ------ELIEVRPE----EERWRGAIERvlggfaltllvppehyaaalrwvNRLHLrGRLVYErVRTGLPDPERPRLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  921 VLQTKLSNKD--------EELKAFCLHEKVEREElqrQLKQEEDR----CLMY-KQEIVVKD-----KEVNFL------K 976
Cdd:COG4913    535 SLAGKLDFKPhpfrawleAELGRRFDYVCVDSPE---ELRRHPRAitraGQVKgNGTRHEKDdrrriRSRYVLgfdnraK 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  977 MAmvAKEEEINSLMQSIHSGEEKASAFQDLQEkrheeqkqaisTLEIRLSDAHRLLEEKASSIEmqtsqVMQLQRDLSTE 1056
Cdd:COG4913    612 LA--ALEAELAELEEELAEAEERLEALEAELD-----------ALQERREALQRLAEYSWDEID-----VASAEREIAEL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1057 QERVVSLEQSMkvsddalihcklekealkNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQAR 1136
Cdd:COG4913    674 EAELERLDASS------------------DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1137 LGTASALAS-EKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTA--------SALASEKDSQLE--- 1204
Cdd:COG4913    736 LEAAEDLARlELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLEslp 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1205 ---LLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEkdsQLESLHAELKE---RDGLRIQaaeMEAR 1278
Cdd:COG4913    816 eylALLDRLEEDGLPEYEERFKELLNENSIEFVADLLSKLRRAIREIKE---RIDPLNDSLKRipfGPGRYLR---LEAR 889

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1338812033 1279 HKELEEsIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQ 1331
Cdd:COG4913    890 PRPDPE-VREFRQELRAVTSGASLFDEELSEARFAALKRLIERLRSEEEESDR 941
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1096-1639 6.18e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 61.67  E-value: 6.18e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1096 EKLKGELEELKREHENLRLQVAETETLHNKSE----ERIAQLQARLgtaSALASEKDSQLELLHAELKERDSLRIQaaem 1171
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKfylrQSVIDLQTKL---QEMQMERDAMADIRRRESQSQEDLRNQ---- 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1172 earhkeLEESIAQLQARLGTASALASEKDSQLEllhaelkerdslriQAAEMEARHKELEESIAQLQAQLGTASVLASEK 1251
Cdd:pfam15921  147 ------LQNTVHELEAAKCLKEDMLEDSNTQIE--------------QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1252 DSQLESLHaelkerdgLRIQAAEMEARHKELEESIAQLQARL----GTASALASGKQSELDLLHKEVREREKLRIRAVEV 1327
Cdd:pfam15921  207 HDSMSTMH--------FRSLGSAISKILRELDTEISYLKGRIfpveDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1328 EEAQhkeLEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTAT-----SLAAVQKRV---N 1399
Cdd:pfam15921  279 EITG---LTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKrmyedKIEELEKQLvlaN 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1400 EKLNEDIRRLDVVRQESMERDAlRIRAIEAeDLKRKEMEETIVKLKSEIL-----THTTKLEHLNKWHQQQLSVLRNENQ 1474
Cdd:pfam15921  356 SELTEARTERDQFSQESGNLDD-QLQKLLA-DLHKREKELSLEKEQNKRLwdrdtGNSITIDHLRRELDDRNMEVQRLEA 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1475 TLLSMKE----SMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAE----------NERLIGDLQEQLQAKTEAMK 1540
Cdd:pfam15921  434 LLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEEltakkmtlesSERTVSDLTASLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1541 HCKAQVQMAKT----------HYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMK--------------LLQIELD 1596
Cdd:pfam15921  514 ATNAEITKLRSrvdlklqelqHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEnmtqlvgqhgrtagAMQVEKA 593

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1338812033 1597 QAKLSEKDLALKVNSLQAQVDYADRQLREYAKHGIDTTLNTCK 1639
Cdd:pfam15921  594 QLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVK 636
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1167-1394 6.26e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 6.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1167 QAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERdslriQAAEMEARHKELEESIAQLQAQLGTASV 1246
Cdd:COG4913    242 EALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQR-----RLELLEAELEELRAELARLEAELERLEA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1247 LASEKDSQLESLHAELKERDGLRIQAAEMEARHkeLEESIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAVE 1326
Cdd:COG4913    317 RLDALREELDELEAQIRGNGGDRLEQLEREIER--LERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE 394

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033 1327 VEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEkdhvIKTQHMELESTVTQLKEQLHTATSLAAV 1394
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIAS----LERRKSNIPARLLALRDALAEALGLDEA 458
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 865-1605 6.34e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 61.34  E-value: 6.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  865 EMKQIQMELGTVKKAKDDMELDLQSsIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFcLHEkver 944
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKE-LEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEI-LHE---- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  945 eeLQRQLKQEEDRCLMYKQEivVKDKEVNFLKMAMVAKEEEinSLMQSIHSgeEKASAfqDLQEKRHEEQKQAISTLEIR 1024
Cdd:pfam01576   80 --LESRLEEEEERSQQLQNE--KKKMQQHIQDLEEQLDEEE--AARQKLQL--EKVTT--EAKIKKLEEDILLLEDQNSK 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1025 LSDAHRLLEEKASSIEMQtsqvmqlqrdLSTEQERVVSLeQSMKVSDDALIHCKLEKeaLKNEVTSLQELAE---KLKGE 1101
Cdd:pfam01576  150 LSKERKLLEERISEFTSN----------LAEEEEKAKSL-SKLKNKHEAMISDLEER--LKKEEKGRQELEKakrKLEGE 216

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1102 LEELKREHENLRLQVAETETLHNKSEERIAQLQARL---GTASALASEKDSQLELLHAELKER-DSLRIQAAEMEARHKE 1177
Cdd:pfam01576  217 STDLQEQIAELQAQIAELRAQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDlESERAARNKAEKQRRD 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1178 LEESIAQLQARL-------GTASALASEKDSQLELLHAELK-ERDSLRIQAAEMEARHKE-------------------- 1229
Cdd:pfam01576  297 LGEELEALKTELedtldttAAQQELRSKREQEVTELKKALEeETRSHEAQLQEMRQKHTQaleelteqleqakrnkanle 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1230 -----LEESIAQLQAQLGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQ 1304
Cdd:pfam01576  377 kakqaLESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE---LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1305 SELDLLHKEVRE----------------REKL----RIRAVEV-----------EEAQHKELEERVTEASTLASERKSQL 1353
Cdd:pfam01576  454 GKNIKLSKDVSSlesqlqdtqellqeetRQKLnlstRLRQLEDernslqeqleeEEEAKRNVERQLSTLQAQLSDMKKKL 533

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1354 DSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQ------------ESMERDA 1421
Cdd:pfam01576  534 EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQlvsnlekkqkkfDQMLAEE 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1422 LRIRAIEAEDLKR-----KEMEETIVKLKSEILTHTTKLEHLNKWHQQqlsvLRNENQTLLSMKESMVKEQEVSQRVKVS 1496
Cdd:pfam01576  614 KAISARYAEERDRaeaeaREKETRALSLARALEEALEAKEELERTNKQ----LRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1497 LESKLKLAGQELSVL---------------LPLQECKAENERligDLQEQLQAKTEAMKHCKAQVQMAKTHYN------- 1554
Cdd:pfam01576  690 LEQQVEEMKTQLEELedelqatedaklrleVNMQALKAQFER---DLQARDEQGEEKRRQLVKQVRELEAELEderkqra 766

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033 1555 ----GKKQQLLEVQEKAQTLENTLESRDQEVKVLR---SEMKLLQIELDQAKLSEKDL 1605
Cdd:pfam01576  767 qavaAKKKLELDLKELEAQIDAANKGREEAVKQLKklqAQMKDLQRELEEARASRDEI 824
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 518-1615 6.67e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 61.34  E-value: 6.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  518 QKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSkEEEARSNAEEwARERHEISRQQ--EVL--MEARET 593
Cdd:pfam01576    8 QAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQA-ETELCAEAEE-MRARLAARKQEleEILheLESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  594 ISRERDaiateyQHFQQEKEevacKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLE---- 669
Cdd:pfam01576   86 EEEERS------QQLQNEKK----KMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerk 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  670 ------LDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECA-------KGLRDELE 736
Cdd:pfam01576  156 lleeriSEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLqeqiaelQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  737 VERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEE----GREVERGL-TA 811
Cdd:pfam01576  236 AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEElealKTELEDTLdTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  812 ARDQAFLTIKEREAETSKLRSEAEALSSKVILAEE-----------AKAIELAKK-----DDEMQVLSKEMKQIQMELGT 875
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKALEEETRSHEAQLQEMrqkhtqaleelTEQLEQAKRnkanlEKAKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  876 VKKAKDDMEL---DLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSnkDEELKAFCLHEKVEREELQRQ-- 950
Cdd:pfam01576  396 LQQAKQDSEHkrkKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN--EAEGKNIKLSKDVSSLESQLQdt 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  951 --LKQEEDRclmykQEIVVKDKevnflkmaMVAKEEEINSLMQSIHSGEEKASAFQdlqekrheeqkQAISTLEIRLSDA 1028
Cdd:pfam01576  474 qeLLQEETR-----QKLNLSTR--------LRQLEDERNSLQEQLEEEEEAKRNVE-----------RQLSTLQAQLSDM 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1029 HRLLEEKASSIEMQTSQVMQLQRDLsteqervvsleqsmkvsdDALIHCKLEKEAlknEVTSLQELAEKLKGELEELKRE 1108
Cdd:pfam01576  530 KKKLEEDAGTLEALEEGKKRLQREL------------------EALTQQLEEKAA---AYDKLEKTKNRLQQELDDLLVD 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1109 HENLRLQVAETEtlhnKSEERIAQLQARLGTASALASEKDSQLEllhAELKERD----SLRIQAAEMEARHKELEESIAQ 1184
Cdd:pfam01576  589 LDHQRQLVSNLE----KKQKKFDQMLAEEKAISARYAEERDRAE---AEAREKEtralSLARALEEALEAKEELERTNKQ 661

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1185 LQARLgtaSALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESI-----AQLQAQLGTASVLAS-EKDSQLESL 1258
Cdd:pfam01576  662 LRAEM---EDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELqatedAKLRLEVNMQALKAQfERDLQARDE 738

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1259 HAELKERDGLRiQAAEMEArhkELEESIAQlqarlgTASALASGKQSELDLlhkevrereklriraveveeaqhKELEER 1338
Cdd:pfam01576  739 QGEEKRRQLVK-QVRELEA---ELEDERKQ------RAQAVAAKKKLELDL-----------------------KELEAQ 785

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1339 VTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRrldVVRQESME 1418
Cdd:pfam01576  786 IDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASER---ARRQAQQE 862

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1419 RDALRI--------RAIEAEDLKRkeMEETIVKLKSEILTHTTKLEHLNKwHQQQLSVLRNENQTLLSMKESMVKEQEV- 1489
Cdd:pfam01576  863 RDELADeiasgasgKSALQDEKRR--LEARIAQLEEELEEEQSNTELLND-RLRKSTLQVEQLTTELAAERSTSQKSESa 939

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1490 -SQRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQA--------------KTEAMKHCKAQVQMAKTHYN 1554
Cdd:pfam01576  940 rQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQLEQesrerqaanklvrrTEKKLKEVLLQVEDERRHAD 1019

                         1130      1140      1150      1160      1170      1180
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1555 GKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSEKDLALKVNSLQAQ 1615
Cdd:pfam01576 1020 QYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
mukB PRK04863
chromosome partition protein MukB;
888-1294 7.53e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 61.51  E-value: 7.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  888 QSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFclhEKVER-----EELQRQLkqeedrclmYK 962
Cdd:PRK04863   299 RRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQ---EKIERyqadlEELEERL---------EE 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  963 QEIVVKdkEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEirlsDAHRLLEEKASSIEMQ 1042
Cdd:PRK04863   367 QNEVVE--EADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALE----RAKQLCGLPDLTADNA 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1043 TSQVMQLQRDLSTEQERVVSLEQSMKVSDDAliHCKLEKEAlknevtslqELAEKLKGELE---------ELKREHENLR 1113
Cdd:PRK04863   441 EDWLEEFQAKEQEATEELLSLEQKLSVAQAA--HSQFEQAY---------QLVRKIAGEVSrseawdvarELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1114 LQVaetetlhnkseERIAQLQARLGTASALASEKDSQLELLhAELKERDSLRIQAAEmearhkELEESIAQLQARLGTAS 1193
Cdd:PRK04863   510 HLA-----------EQLQQLRMRLSELEQRLRQQQRAERLL-AEFCKRLGKNLDDED------ELEQLQEELEARLESLS 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1194 ALASEKDSQLELLHAELKErdsLRIQAAEMEARHKE---LEESIAQLQAQLGtASVLASEKDSQLESLHAElKERdGLRI 1270
Cdd:PRK04863   572 ESVSEARERRMALRQQLEQ---LQARIQRLAARAPAwlaAQDALARLREQSG-EEFEDSQDVTEYMQQLLE-RER-ELTV 645

                          410       420
                   ....*....|....*....|....
gi 1338812033 1271 QAAEMEARHKELEESIAQLQARLG 1294
Cdd:PRK04863   646 ERDELAARKQALDEEIERLSQPGG 669
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 211-748 8.44e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 8.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEremqvsQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLK 290
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQ------DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQMERKIDDLTEEngilsvqmreiFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLN 370
Cdd:COG1196    345 ELEEAEEELEEAEAELAEAEEA-----------LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  371 EQIQILQGKISILEDELSKAKAETlgggevmgpimewERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFE 450
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEE-------------EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  451 AEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQ-RELAVTNFSQKVDVERKRVEK 529
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEVAA 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  530 LTEEMEKQERFAQKTIQEL---HERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQ 606
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLdkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  607 HFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRchgLELDSEAQRASHQEEVESL 686
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA---LLAEEEEERELAEAEEERL 717

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338812033  687 KRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAEcAKGLRDELEVERSKHKETLAA 748
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP-EPPDLEELERELERLEREIEA 778
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1071-1241 1.06e-08

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 58.01  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1071 DDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASalaSEKDsq 1150
Cdd:COG1579     16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR---NNKE-- 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1151 lelLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERdslriqAAEMEARHKEL 1230
Cdd:COG1579     91 ---YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEE------LAELEAELEEL 161

                          170
                   ....*....|.
gi 1338812033 1231 EESIAQLQAQL 1241
Cdd:COG1579    162 EAEREELAAKI 172
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 349-1059 1.09e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 1.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  349 ESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMgpimewERLNQEIADLNHKLSQLQEII 428
Cdd:TIGR00618  190 KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH------AYLTQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  429 IQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQ 508
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  509 RELAVTNFSQKVDVERK-RVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQ---Q 584
Cdd:TIGR00618  344 RRLLQTLHSQEIHIRDAhEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFrdlQ 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  585 EVLMEARETISRERDAIATEYQHFQQEKEEvacklnqqivlleeqQSVEWSLLSELRKEKQELEQKVSSIEAIVDNlRTR 664
Cdd:TIGR00618  424 GQLAHAKKQQELQQRYAELCAAAITCTAQC---------------EKLEKIHLQESAQSLKEREQQLQTKEQIHLQ-ETR 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  665 CHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEvERSKHKE 744
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRA-SLKEQMQ 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  745 TLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKvqQEKMRVDASMAKLIEEGREVERGLTAARDQAF------- 817
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE--AEDMLACEQHALLRKLQPEQDLQDVRLHLQQCsqelalk 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  818 LTIKEREAETSKLRSEAEALSSKVILAEEAKAIELAkKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQ 897
Cdd:TIGR00618  645 LTALHALQLTLTQERVREHALSIRVLPKELLASRQL-ALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEI 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  898 LLVLRFQMNELEEsanQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLkQEEDRCLMYKQEIVVKDKEVNFLKM 977
Cdd:TIGR00618  724 ENASSSLGSDLAA---REDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAAL-QTGAELSHLAAEIQFFNRLREEDTH 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  978 AMVAKEEEINslmQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEmQTSQVMQLQRDLSTEQ 1057
Cdd:TIGR00618  800 LLKTLEAEIG---QEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSK-QLAQLTQEQAKIIQLS 875


                   ..
gi 1338812033 1058 ER 1059
Cdd:TIGR00618  876 DK 877
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 211-1016 1.10e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLK 290
Cdd:pfam02463  193 EELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQMERKIDDLTEENGILSVQMR-------EIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQAL 363
Cdd:pfam02463  273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLklerrkvDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  364 SQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMG----PIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIE 439
Cdd:pfam02463  353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKlkeeELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEIL 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  440 MMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQ----RELAVTN 515
Cdd:pfam02463  433 EEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKeskaRSGLKVL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  516 FSQKVDVE-------RKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVL- 587
Cdd:pfam02463  513 LALIKDGVggriisaHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLk 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  588 ---MEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTR 664
Cdd:pfam02463  593 siaVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELT 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  665 CHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKivEEHIALRDELSAAAECAKGLRDELEVERSKHKE 744
Cdd:pfam02463  673 KELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL--EAEELLADRVQEAQDKINEELKLLKQKIDEEEE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  745 TLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHlgQQLSKVQQEKMRVDASMAKLIEEGREvERGLTAARDQAFLTIKERE 824
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREK--TEKLKVEEEKEEKLKAQEEELRALEE-ELKEEAELLEEEQLLIEQE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  825 AETSKLRSEAEALSSKVILAEEAKAIELAKKDDEMQ-VLSKEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRF 903
Cdd:pfam02463  828 EKIKEEELEELALELKEEQKLEKLAEEELERLEEEItKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  904 QMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKE 983
Cdd:pfam02463  908 KLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE 987

                          810       820       830
                   ....*....|....*....|....*....|...
gi 1338812033  984 EEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQ 1016
Cdd:pfam02463  988 ERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
450-1021 1.40e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  450 EAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEaQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEK 529
Cdd:PRK02224   212 ESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  530 LTEEMEkqERFAQKTIQELH-ERVDHLGSVLNSKEEEARSNAEEwarERHEISrqqevlmEARETISRERDAiATEYQHF 608
Cdd:PRK02224   291 LEEERD--DLLAEAGLDDADaEAVEARREELEDRDEELRDRLEE---CRVAAQ-------AHNEEAESLRED-ADDLEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  609 QQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLrtrchgleldseaqrASHQEEVESLKR 688
Cdd:PRK02224   358 AEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA---------------EDFLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  689 KLHEAESILgvyEGKLADHQKIVEEHIALRDElSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQ 768
Cdd:PRK02224   423 ELREREAEL---EATLRTARERVEEAEALLEA-GKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERL 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  769 NMSVEMQHLGQQLSKVQQEKMRVDasmaKLIEEGREvergltaardqaflTIKEREAETSKLRSEAEALSSKvilAEEAK 848
Cdd:PRK02224   499 ERAEDLVEAEDRIERLEERREDLE----ELIAERRE--------------TIEEKRERAEELRERAAELEAE---AEEKR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  849 AiELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDME--LDLQSSIEKRQEQLLVLRFQMNELEESANQKEteiEVLQTKL 926
Cdd:PRK02224   558 E-AAAEAEEEAEEAREEVAELNSKLAELKERIESLEriRTLLAAIADAEDEIERLREKREALAELNDERR---ERLAEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  927 SNKDEelkafcLHEKVEREELQrQLKQEEDRCLMYKQEIVVKDKEvnflkmamvaKEEEINSLMQSIHSGEEKASAFQDL 1006
Cdd:PRK02224   634 ERKRE------LEAEFDEARIE-EAREDKERAEEYLEQVEEKLDE----------LREERDDLQAEIGAVENELEELEEL 696

                          570
                   ....*....|....*..
gi 1338812033 1007 QEKRH--EEQKQAISTL 1021
Cdd:PRK02224   697 RERREalENRVEALEAL 713
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1116-1409 1.60e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1116 VAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAE---LKERDSLRIQAAEMEA-----RHKELEESIAQLQA 1187
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKREYEGyellkEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1188 RLGTASALASEKDSQLELLHAELKERDSLRIQAAE-----MEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAEL 1262
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1263 KERDGLRiqaAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVRE--------REKLRIRAVEVEEAQHkE 1334
Cdd:TIGR02169  325 AKLEAEI---DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkefaetRDELKDYREKLEKLKR-E 400

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033 1335 LEERVTEASTLAsERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRL 1409
Cdd:TIGR02169  401 INELKRELDRLQ-EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 218-1360 1.67e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 60.19  E-value: 1.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  218 QLVQEREMRDELE-RELASR-SQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQCQEL 295
Cdd:pfam01576   15 QKVKERQQKAESElKELEKKhQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  296 KTNKTQMERKIDDLTEEngilsvqmreifsrLSSAEAAVQKLSAEQessqVEWESKRGLLESELGQALSQKEYLNEQIQI 375
Cdd:pfam01576   95 QNEKKKMQQHIQDLEEQ--------------LDEEEAARQKLQLEK----VTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  376 LQGKISIL------EDELSKAKAETLGGGEVMGPIME-----WERLNQEIADLNHKL----SQLQEIIIQLQKEKKEIEM 440
Cdd:pfam01576  157 LEERISEFtsnlaeEEEKAKSLSKLKNKHEAMISDLEerlkkEEKGRQELEKAKRKLegesTDLQEQIAELQAQIAELRA 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  441 MYEVEKTKFEAEKARLEElvselnkmltvQRGEREALEQALREqrvsLEAQIEALTADIASLTEAVQQRELAVTNFSQKV 520
Cdd:pfam01576  237 QLAKKEEELQAALARLEE-----------ETAQKNNALKKIRE----LEAQISELQEDLESERAARNKAEKQRRDLGEEL 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  521 DVERKRVEKLTEEMEKQERFAQKTIQElherVDHLGSVLnskEEEARSNAEEWARERHEISRQQEVLMEARETISRERDA 600
Cdd:pfam01576  302 EALKTELEDTLDTTAAQQELRSKREQE----VTELKKAL---EEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKAN 374

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  601 IATEYQHFQQEKEEVACKLnqqivlleeqqsvewsllSELRKEKQELEQKVSSIEAIVDNLRTRCHglelDSEAQRASHQ 680
Cdd:pfam01576  375 LEKAKQALESENAELQAEL------------------RTLQQAKQDSEHKRKKLEGQLQELQARLS----ESERQRAELA 432

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  681 EEVESLKRKLHEAESILGVYEGKLADHQKIVeehialrdelsAAAECAKGLRDELEVERSKHKETLAAKLQS----KSQM 756
Cdd:pfam01576  433 EKLSKLQSELESVSSLLNEAEGKNIKLSKDV-----------SSLESQLQDTQELLQEETRQKLNLSTRLRQledeRNSL 501

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  757 MEEMRELEEKTQNMSVEMQHLGQQLSKVQQeKMRVDASMAKLIEEGREvergltaardqafltikereaetsKLRSEAEA 836
Cdd:pfam01576  502 QEQLEEEEEAKRNVERQLSTLQAQLSDMKK-KLEEDAGTLEALEEGKK------------------------RLQRELEA 556

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  837 LSSKvilaeeakaieLAKKDDEMQVLSKEMKQIQMELgtvkkakDDMELDLQSsiekrQEQLLvlrfqmneleesanqke 916
Cdd:pfam01576  557 LTQQ-----------LEEKAAAYDKLEKTKNRLQQEL-------DDLLVDLDH-----QRQLV----------------- 596

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  917 TEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEivvkdkevnfLKMAMVAKEEEINSLMQSIHSG 996
Cdd:pfam01576  597 SNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARA----------LEEALEAKEELERTNKQLRAEM 666

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  997 EEKASAFQDLQEKRHEeqkqaistleirLSDAHRLLEEKASsiEMQTsQVMQLQRDLSTEQERVVSLE---QSMKVSDDA 1073
Cdd:pfam01576  667 EDLVSSKDDVGKNVHE------------LERSKRALEQQVE--EMKT-QLEELEDELQATEDAKLRLEvnmQALKAQFER 731

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1074 LIHCKLEKEalknevtslQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLEL 1153
Cdd:pfam01576  732 DLQARDEQG---------EEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKK 802

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1154 LHAELKE-----------RDSLRIQAAEMEARHKELEESIAQLQARLGTASAL----ASEKDSQLELLHAELKERDSLRI 1218
Cdd:pfam01576  803 LQAQMKDlqreleearasRDEILAQSKESEKKLKNLEAELLQLQEDLAASERArrqaQQERDELADEIASGASGKSALQD 882

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKerdGLRIQAAEMEARHKELEESIAQLQARLG---- 1294
Cdd:pfam01576  883 EKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELA---AERSTSQKSESARQQLERQNKELKAKLQemeg 959

                         1130      1140      1150      1160      1170      1180      1190
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338812033 1295 --------TASALASGKQSELDLLHKEVREREkLRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEM 1360
Cdd:pfam01576  960 tvkskfksSIAALEAKIAQLEEQLEQESRERQ-AANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRM 1032
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1005-1298 1.71e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.97  E-value: 1.71e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1005 DLQEKRHEEQKQAISTLEirlsDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDAlihcklekeal 1084
Cdd:COG3096    406 DVQQTRAIQYQQAVQALE----KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAA----------- 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1085 KNEVTSLQELAEKLKGELE---------ELKREHENLRLQVaetetlhnkseERIAQLQARLGTASALASEKDSQLELLh 1155
Cdd:COG3096    471 RRQFEKAYELVCKIAGEVErsqawqtarELLRRYRSQQALA-----------QRLQQLRAQLAELEQRLRQQQNAERLL- 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1156 AELKERDSLRIQAAEM-EARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESI 1234
Cdd:COG3096    539 EEFCQRIGQQLDAAEElEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE---LAARAPAWLAAQDALERLR 615

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKERDglriqaaEMEARHKELEESIAQLQARLGTASA 1298
Cdd:COG3096    616 EQSGEALADSQEVTAAMQQLLEREREATVERD-------ELAARKQALESQIERLSQPGGAEDP 672
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
886-1365 1.74e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  886 DLQSSIEKRQEQLLVLRfQMNELEESANQKETEIEVLQTklsnkdeelkafcLHEKVEREELQRQLKQEEDRCLMYKQEI 965
Cdd:COG4913    239 RAHEALEDAREQIELLE-PIRELAERYAAARERLAELEY-------------LRAALRLWFAQRRLELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  966 VVKDKEVNFLKMAMVAKEEEINSLMQSI--HSGEEKASAFQDLQ--EKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEM 1041
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEAQIrgNGGDRLEQLEREIErlERELEERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1042 QTSQVMQLQRDLSTEQERVVSLEQSMKvsdDALIHCKLEKEALKNEVTSLQ---------------ELAEKLK------- 1099
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAE---AALRDLRRELRELEAEIASLErrksniparllalrdALAEALGldeaelp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1100 --GELEELKREHE-----------NLRL----------QVAE-TETLHNKSEERIAQLQARLGTASALASEKDS---QLE 1152
Cdd:COG4913    462 fvGELIEVRPEEErwrgaiervlgGFALtllvppehyaAALRwVNRLHLRGRLVYERVRTGLPDPERPRLDPDSlagKLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1153 L--------LHAELKER---------DSLR-----IQAAEM--------------------------EARHKELEESIAQ 1184
Cdd:COG4913    542 FkphpfrawLEAELGRRfdyvcvdspEELRrhpraITRAGQvkgngtrhekddrrrirsryvlgfdnRAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1185 LQARLGTASALASEKDSQLELLHAELKERDSLRiQAAEMEARHKELEESIAQLQAQLgtASVLASEKD-----SQLESLH 1259
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEAEL--ERLDASSDDlaaleEQLEELE 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1260 AEL----KERDGLRIQAAEMEARHKELEESIAQLQARLGTASALAS-GKQSELDLLHKEVREReklriravEVEEAQHKE 1334
Cdd:COG4913    699 AELeeleEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlELRALLEERFAAALGD--------AVERELREN 770

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1338812033 1335 LEERVTEASTLASERKSQLDSLHNEMNEKDH 1365
Cdd:COG4913    771 LEERIDALRARLNRAEEELERAMRAFNREWP 801
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1033-1540 1.96e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 1.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1033 EEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENL 1112
Cdd:PRK03918   199 EKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1113 RLQVAETETLHNKSEERIA------QLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQ 1186
Cdd:PRK03918   279 EEKVKELKELKEKAEEYIKlsefyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1187 ARLGTASAlASEKDSQLELLHAELKERDSLRIQAA--EMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLH----- 1259
Cdd:PRK03918   359 ERHELYEE-AKAKKEELERLKKRLTGLTPEKLEKEleELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgk 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1260 -----AELKERDGLRIQA------AEMEARHKELEESIAQLQARLGTASALASgKQSELDLLHKEVRE----REKLRIRA 1324
Cdd:PRK03918   438 cpvcgRELTEEHRKELLEeytaelKRIEKELKEIEEKERKLRKELRELEKVLK-KESELIKLKELAEQlkelEEKLKKYN 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1325 VEVEEAQHKELEERVTEASTLaserKSQLDSLHNEMNEKDhviktqhmELESTVTQLKEQLHTatslaavqkrVNEKLNE 1404
Cdd:PRK03918   517 LEELEKKAEEYEKLKEKLIKL----KGEIKSLKKELEKLE--------ELKKKLAELEKKLDE----------LEEELAE 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1405 DIRRLDVVRQESMERDALRIRAIEAEDLK-------RKEMEETIVKLKSEILTHTTKLEHLNKwHQQQLSVLRNENQTLL 1477
Cdd:PRK03918   575 LLKELEELGFESVEELEERLKELEPFYNEylelkdaEKELEREEKELKKLEEELDKAFEELAE-TEKRLEELRKELEELE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338812033 1478 smKESMVKEQEVSQRVKVSLESKLKLAGQELSvllPLQECKAENERLIGDLQEQLQAKTEAMK 1540
Cdd:PRK03918   654 --KKYSEEEYEELREEYLELSRELAGLRAELE---ELEKRREEIKKTLEKLKEELEEREKAKK 711
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1072-1605 2.10e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 2.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1072 DALIHCKLEKEALKNEVTSLQEL---AEKLKGELEELKREHENLRLQVAETETLHNK---SEERIAQLQARLGTASALAS 1145
Cdd:PRK03918   138 DAILESDESREKVVRQILGLDDYenaYKNLGEVIKEIKRRIERLEKFIKRTENIEELikeKEKELEEVLREINEISSELP 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1146 EKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEA 1225
Cdd:PRK03918   218 ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1226 RHKELEESIAQLQaqlgTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASgKQS 1305
Cdd:PRK03918   298 LSEFYEEYLDELR----EIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-KKE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1306 ELDLLHKE---------VREREKLRIRAVEVEEAQhKELEERVTEASTLASERKSQLDSLHN------------EMNEKD 1364
Cdd:PRK03918   373 ELERLKKRltgltpeklEKELEELEKAKEEIEEEI-SKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRK 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1365 HVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDiRRLDVVRQ--ESMERDALRIRAIEAEDLKRK-----EM 1437
Cdd:PRK03918   452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE-SELIKLKElaEQLKELEEKLKKYNLEELEKKaeeyeKL 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1438 EETIVKLKSEILTHTTKLEHLNKWhQQQLSVLRNENQTLLSMKESMVKE---------QEVSQRVKvslesKLKLAGQEL 1508
Cdd:PRK03918   531 KEKLIKLKGEIKSLKKELEKLEEL-KKKLAELEKKLDELEEELAELLKEleelgfesvEELEERLK-----ELEPFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1509 SVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEvqEKAQTLENTLESRDQEVKVLRSEM 1588
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAEL 682

                          570
                   ....*....|....*..
gi 1338812033 1589 KLLQIELDQAKLSEKDL 1605
Cdd:PRK03918   683 EELEKRREEIKKTLEKL 699
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 433-1231 2.33e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.60  E-value: 2.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  433 KEKKEIEMMYEvEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQrela 512
Cdd:TIGR00618  163 KEKKELLMNLF-PLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQ---- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  513 vtnfsqkvdvERKRVEKLTEEMEKQERfAQKTIQELHERVDHLgsvlnsKEEEARSNAEEWARERHEISRQQEVLMEARE 592
Cdd:TIGR00618  238 ----------TQQSHAYLTQKREAQEE-QLKKQQLLKQLRARI------EELRAQEAVLEETQERINRARKAAPLAAHIK 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  593 TISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKvssIEAIVDNLRTRCHGLELDS 672
Cdd:TIGR00618  301 AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIR---DAHEVATSIREISCQQHTL 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  673 EAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAEcakglRDELEVERSKHKETLAAK-LQ 751
Cdd:TIGR00618  378 TQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK-----QQELQQRYAELCAAAITCtAQ 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  752 SKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVErGLTAARDQAFLTIKEREAETSKLR 831
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQ 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  832 SeaealsskviLAEEAKAIELAKKDDEMQvLSKEMKQIQmelgtvkkakddmelDLQSSIEKRQEQLLVLRFQMNELEES 911
Cdd:TIGR00618  532 R----------GEQTYAQLETSEEDVYHQ-LTSERKQRA---------------SLKEQMQEIQQSFSILTQCDNRSKED 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  912 ANQKETEIEVLQTKLSNKDEELKAfcLHEKVEREELQRQLKQEEDRCLMYKQEIvvkDKEVNFLKMAMVAKEEEINSLMQ 991
Cdd:TIGR00618  586 IPNLQNITVRLQDLTEKLSEAEDM--LACEQHALLRKLQPEQDLQDVRLHLQQC---SQELALKLTALHALQLTLTQERV 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  992 SIHSGEEKAsaFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSD 1071
Cdd:TIGR00618  661 REHALSIRV--LPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1072 DALIHcklekealknevtSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARlgtaSALASEKDSQL 1151
Cdd:TIGR00618  739 DALNQ-------------SLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFF----NRLREEDTHLL 801

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1152 ELLHAELKER--DSLRIQAAEMEARHKELEesiaQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKE 1229
Cdd:TIGR00618  802 KTLEAEIGQEipSDEDILNLQCETLVQEEE----QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877


                   ..
gi 1338812033 1230 LE 1231
Cdd:TIGR00618  878 LN 879
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1021-1647 2.35e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.60  E-value: 2.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1021 LEIRLSDAHRLLEEKASSIEMQTSQVMQ-LQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQElAEKLK 1099
Cdd:TIGR00618  181 LALMEFAKKKSLHGKAELLTLRSQLLTLcTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-QLKKQ 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1100 GELEELKREHENLRLQVAETETLHNKSEERiaQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELE 1179
Cdd:TIGR00618  260 QLLKQLRARIEELRAQEAVLEETQERINRA--RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1180 ESIAQLQARLGTASA-------LASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIA---QLQAQLGTASVL-A 1248
Cdd:TIGR00618  338 SSIEEQRRLLQTLHSqeihirdAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKeldILQREQATIDTRtS 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1249 SEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDL--LHKEVREREKLRIRAVE 1326
Cdd:TIGR00618  418 AFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKeqIHLQETRKKAVVLARLL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1327 VEEAQHKELEERVTE------ASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNE 1400
Cdd:TIGR00618  498 ELQEEPCPLCGSCIHpnparqDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQ 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1401 KLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNEnQTLLSMK 1480
Cdd:TIGR00618  578 CDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALH-ALQLTLT 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1481 ESMVKEQEVSQRV--KVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQM---AKTHYNG 1555
Cdd:TIGR00618  657 QERVREHALSIRVlpKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENAsssLGSDLAA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1556 KKQQLLEVQEKAQTLENTL---ESRDQEVKVLRSEMKL-LQIELDQAKLSEKDLALKVNSLQAQVDYADRQLREYAKHGI 1631
Cdd:TIGR00618  737 REDALNQSLKELMHQARTVlkaRTEAHFNNNEEVTAALqTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDE 816

                          650
                   ....*....|....*.
gi 1338812033 1632 DTTLNTCKPPSQEERS 1647
Cdd:TIGR00618  817 DILNLQCETLVQEEEQ 832
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1125-1351 2.56e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 2.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1125 KSEERIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLE 1204
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA---LERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1205 LLHAELKErdslRIQAAEMEARHKELE-----ESIAQLQAQLGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARH 1279
Cdd:COG4942    101 AQKEELAE----LLRALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAE---LAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338812033 1280 KELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKlRIRAVEVEEAQHKELEERVTEASTLASERKS 1351
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAA-ELAELQQEAEELEALIARLEAEAAAAAERTP 244
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 261-506 2.97e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  261 SEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEengilsvQMREIFSRLSSAEAAVQKLSAE 340
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-------RIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  341 QESSQVEWESKRGLLESELGQAlsqkeYLNEQIQILQGKISiledelSKAKAETLGGGEVMGPIMewERLNQEIADLNHK 420
Cdd:COG4942     92 IAELRAELEAQKEELAELLRAL-----YRLGRQPPLALLLS------PEDFLDAVRRLQYLKYLA--PARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  421 LSQLQEIIIQLQKEKKEIemmyEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQ---ALREQRVSLEAQIEALTA 497
Cdd:COG4942    159 LAELAALRAELEAERAEL----EALLAELEEERAALEALKAERQKLLARLEKELAELAAelaELQQEAEELEALIARLEA 234


                   ....*....
gi 1338812033  498 DIASLTEAV 506
Cdd:COG4942    235 EAAAAAERT 243
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 211-466 1.01e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELAsrsqviteremqvsqlQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLK 290
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLS----------------HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 QCQELKTNKTQ----MERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQ---ESSQVEWESKRGLLESELGQAL 363
Cdd:TIGR02169  830 YLEKEIQELQEqridLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdlKKERDELEAQLRELERKIEELE 909

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  364 SQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEI---IIQLQKEKKEIEM 440
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVnmlAIQEYEEVLKRLD 989

                          250       260
                   ....*....|....*....|....*.
gi 1338812033  441 MYEVEKTKFEAEKARLEELVSELNKM 466
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKK 1015
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 269-754 1.09e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  269 KEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKlSAEQESSQVEW 348
Cdd:TIGR04523  145 TEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQK-NKSLESQISEL 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  349 ESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAetlgggEVMGPIMEWERLNQEIADLNHKLSQLQEII 428
Cdd:TIGR04523  224 KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK------QLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  429 IQLQKEK--------KEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALE---QALREQRVSLEAQIEALTA 497
Cdd:TIGR04523  298 SDLNNQKeqdwnkelKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSEsenSEKQRELEEKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  498 DIASLTEAVQQRELAVTNFSQKVdverKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARER 577
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKI----QNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKE 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  578 HEIS---RQQEVLMEARETISRERDAIATEYQHFQQE---KEEVACKLNQQIVLLEEQQSV---EWSLLSE----LRKEK 644
Cdd:TIGR04523  454 LIIKnldNTRESLETQLKVLSRSINKIKQNLEQKQKElksKEKELKKLNEEKKELEEKVKDltkKISSLKEkiekLESEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  645 QELEQKVSSIEAIVDNLRTRCHGLELDSEAQraSHQEEVESLKrklHEAESILGVYEGKLADHQKIVEEHIALRDELSAA 724
Cdd:TIGR04523  534 KEKESKISDLEDELNKDDFELKKENLEKEID--EKNKEIEELK---QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEK 608

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1338812033  725 AECAKGLRDELEVERSKHK--ETLAAKLQSKS 754
Cdd:TIGR04523  609 EKKISSLEKELEKAKKENEklSSIIKNIKSKK 640
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1000-1381 1.31e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 57.27  E-value: 1.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1000 ASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQtsqvmqlqRDLSTEQERVVSLEQSMKVSDDaliHCKL 1079
Cdd:COG3096    270 AADYMRHANERRELSERALELRRELFGARRQLAEEQYRLVEMA--------RELEELSARESDLEQDYQAASD---HLNL 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKnevtsLQELAEKLKGELEELKrehENLRLQVAETETLHnkseERIAQLQARLGTASALASEKDSQL-------- 1151
Cdd:COG3096    339 VQTALR-----QQEKIERYQEDLEELT---ERLEEQEEVVEEAA----EQLAEAEARLEAAEEEVDSLKSQLadyqqald 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1152 --------------------ELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELK 1211
Cdd:COG3096    407 vqqtraiqyqqavqalekarALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAG 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1212 E--RDSLRIQAAEMEARHKELE---ESIAQLQAQLGTASVLASEKdSQLESLHAELKERDGLRIQAAEM-EARHKELEES 1285
Cdd:COG3096    487 EveRSQAWQTARELLRRYRSQQalaQRLQQLRAQLAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEElEELLAELEAQ 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1286 IAQLQARLGTASALASGKQSELDLL---HKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNE 1362
Cdd:COG3096    566 LEELEEQAAEAVEQRSELRQQLEQLrarIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVE 645

                          410
                   ....*....|....*....
gi 1338812033 1363 KDHVIKTQHmELESTVTQL 1381
Cdd:COG3096    646 RDELAARKQ-ALESQIERL 663
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
281-502 1.44e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  281 LLTRLHDVLKQCQELKtnktQMERKIDDLTEENGILSvQMREIFSRLSSAEAAVQKLSAEQESSQVeWESKR--GLLESE 358
Cdd:COG4913    223 TFEAADALVEHFDDLE----RAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRL-WFAQRrlELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  359 LGQALSQKEYLNEQIQILQGKISILEDELSKAKAE--TLGGGEVmgpimewERLNQEIADLNHKLSQLQEIIIQLQKEKK 436
Cdd:COG4913    297 LEELRAELARLEAELERLEARLDALREELDELEAQirGNGGDRL-------EQLEREIERLERELEERERRRARLEALLA 369

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033  437 EIEMmyevektKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVS---LEAQIEALTADIASL 502
Cdd:COG4913    370 ALGL-------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAlrdLRRELRELEAEIASL 431
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1045-1241 1.45e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1045 QVMQLQRDLSTEQERVVSLEQsMKVSDDALIHCKLEKEALKNEVTSL-----QELAEKLKGELEELKREHENLRLQVAET 1119
Cdd:COG4913    236 DLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1120 ETLHNKSEERIAQLQArlgtasALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQARL-GTASALASE 1198
Cdd:COG4913    315 EARLDALREELDELEA------QIRGNGGDRLEQLEREIER---LERELEERERRRARLEALLAALGLPLpASAEEFAAL 385

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1338812033 1199 KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQL 1241
Cdd:COG4913    386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 327-551 1.53e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  327 LSSAEAAVQKLSAEQESSQVEWESKRglLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETlgggevmgpime 406
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAE--LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL------------ 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  407 wERLNQEIADLNHKLSQLQEIIIQLQKEKKE----IEMMYEVEKTKF------EAEKARLEELVSELNK-------MLTV 469
Cdd:COG4942     79 -AALEAELAELEKEIAELRAELEAQKEELAEllraLYRLGRQPPLALllspedFLDAVRRLQYLKYLAParreqaeELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  470 QRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELH 549
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                   ..
gi 1338812033  550 ER 551
Cdd:COG4942    238 AA 239
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
271-841 1.83e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 1.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  271 IEQLQRKNEGLLTRLHDVL--KQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLssaEAAVQKLSAEQESSQ--V 346
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQIeeKEEKDLHERLNGLESELAELDEEIERYEEQREQARETR---DEADEVLEEHEERREelE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  347 EWESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAET-LGGGEVmgpimewERLNQEIADLNHKLSQLQ 425
Cdd:PRK02224   255 TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAgLDDADA-------EAVEARREELEDRDEELR 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  426 EIIIQ----LQKEKKEIEMMYEvEKTKFEAEKARLEELVSELNKmltvqrgEREALEQALREQRvsleAQIEALTADIAS 501
Cdd:PRK02224   328 DRLEEcrvaAQAHNEEAESLRE-DADDLEERAEELREEAAELES-------ELEEAREAVEDRR----EEIEELEEEIEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  502 LTEAVQQrelavtnfsqkVDVERKRVEKLTEEMekqerfaQKTIQELHERVDHLGSVLNSkEEEARSNAEEWARERHEIS 581
Cdd:PRK02224   396 LRERFGD-----------APVDLGNAEDFLEEL-------REERDELREREAELEATLRT-ARERVEEAEALLEAGKCPE 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  582 RQQEVLMEAR-ETISRERDAIATEYQHFQQEKEEVAcKLNQQIVLLEEQQSVEwSLLSELRKEKQELEQKVSSIEAIVDN 660
Cdd:PRK02224   457 CGQPVEGSPHvETIEEDRERVEELEAELEDLEEEVE-EVEERLERAEDLVEAE-DRIERLEERREDLEELIAERRETIEE 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  661 LRTRCHGL-----ELDSEAQraSHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGL---- 731
Cdd:PRK02224   535 KRERAEELreraaELEAEAE--EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIerlr 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  732 --RDELEVERSKHKETLAAKLQSKSQmmeemreleektqnmsVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREvergL 809
Cdd:PRK02224   613 ekREALAELNDERRERLAEKRERKRE----------------LEAEFDEARIEEAREDKERAEEYLEQVEEKLDE----L 672

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1338812033  810 TAARD--QAFLTIKERE-AETSKLRSEAEALSSKV 841
Cdd:PRK02224   673 REERDdlQAEIGAVENElEELEELRERREALENRV 707
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1080-1625 2.53e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 55.88  E-value: 2.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKNEVTSLQELAEKLKGELEELKREHENLRLQvaetetLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELK 1159
Cdd:pfam05483  177 EREETRQVYMDLNNNIEKMILAFEELRVQAENARLE------MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQIT 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1160 ERDSlriqaaEMEARHKELEESIAQLQaRLGTASALASEKDSQL-ELLHAELKERDSLRIQAAEMEARHKELEESiaqLQ 1238
Cdd:pfam05483  251 EKEN------KMKDLTFLLEESRDKAN-QLEEKTKLQDENLKELiEKKDHLTKELEDIKMSLQRSMSTQKALEED---LQ 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1239 AQLGTASVLASEKDSQLESLHaelKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVRERE 1318
Cdd:pfam05483  321 IATKTICQLTEEKEAQMEELN---KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMT 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1319 KLRiravEVEEAQHKELEERVTEASTLASERKsQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATS-----LAA 1393
Cdd:pfam05483  398 KFK----NNKEVELEELKKILAEDEKLLDEKK-QFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTseehyLKE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1394 VQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAED--LKRKEMEETIVKLKSEILTHTTKLEHLnkwhQQQLSVLRN 1471
Cdd:pfam05483  473 VEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDmtLELKKHQEDIINCKKQEERMLKQIENL----EEKEMNLRD 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1472 EnqtLLSMKESMVKEQEvsqRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKT 1551
Cdd:pfam05483  549 E---LESVREEFIQKGD---EVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338812033 1552 HYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLrseMKLLQIELDQAKLSEKDLALKVNSLQAQVDYADRQLRE 1625
Cdd:pfam05483  623 KGSAENKQLNAYEIKVNKLELELASAKQKFEEI---IDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKE 693
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 262-661 2.66e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.80  E-value: 2.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  262 EEQEQQPKEIEQLQRKNEGLLTRLHDVLKQCQELKT----NKTQMERKIDDLTEENGILSvqmrEIFSRLSSAEAAVQKL 337
Cdd:TIGR04523  225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDeqnkIKKQLSEKQKELEQNNKKIK----ELEKQLNQLKSEISDL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  338 SAEQESsqvEWESKrglLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAEtlgggevmgpIMEWERLNQEI-AD 416
Cdd:TIGR04523  301 NNQKEQ---DWNKE---LKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE----------LTNSESENSEKqRE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  417 LNHKLSQLQEIIIQLQKEKKEIEMMyEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALE---QALREQRVSLEAQIE 493
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNL-ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEkeiERLKETIIKNNSEIK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  494 ALTADIASLteavqqrELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGS-------------VLN 560
Cdd:TIGR04523  444 DLTNQDSVK-------ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKlneekkeleekvkDLT 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  561 SKEEEARSNAEEWARERHEISRQQEVLMEARETISRE--RDAIATEYQHFQQEKEEvackLNQQIVLLEEQQSVEWSLLS 638
Cdd:TIGR04523  517 KKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEE----LKQTQKSLKKKQEEKQELID 592

                          410       420
                   ....*....|....*....|...
gi 1338812033  639 ELRKEKQELEQKVSSIEAIVDNL 661
Cdd:TIGR04523  593 QKEKEKKDLIKEIEEKEKKISSL 615
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 211-1059 3.69e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 3.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRS----QVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLH 286
Cdd:TIGR00606  193 QVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  287 DVLKQCQELKTNKTQMERKI--------DDLTEENGILSVQMREIFSRLSSAEAAVQKLSAE-----QESSQVEWESKRG 353
Cdd:TIGR00606  273 ALKSRKKQMEKDNSELELKMekvfqgtdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKErrllnQEKTELLVEQGRL 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  354 LLESELGQALSQKEYLNEQIQILQGKISILE-DELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQ 432
Cdd:TIGR00606  353 QLQADRHQEHIRARDSLIQSLATRLELDGFErGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIR 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  433 KEKKEIEMMYEVEKTKfeaekarLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELA 512
Cdd:TIGR00606  433 DEKKGLGRTIELKKEI-------LEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKS 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  513 VTNfsQKVDVERKRvEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARS------------NAEEWARERHEI 580
Cdd:TIGR00606  506 LQN--EKADLDRKL-RKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHsdeltsllgyfpNKKQLEDWLHSK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  581 SRQQEVLMEARETISRERDAIATEYQHFQQE---KEEVACKLNQQIVLLEEQQSVEWSL------LSELRKEKQELEQKV 651
Cdd:TIGR00606  583 SKEINQTRDRLAKLNKELASLEQNKNHINNElesKEEQLSSYEDKLFDVCGSQDEESDLerlkeeIEKSSKQRAMLAGAT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  652 SSIEAIVDNLRTRCHG--------LELDSEAQRAS------------HQEEVES-LKRKLHEAESILGVYEGKLADHQKI 710
Cdd:TIGR00606  663 AVYSQFITQLTDENQSccpvcqrvFQTEAELQEFIsdlqsklrlapdKLKSTESeLKKKEKRRDEMLGLAPGRQSIIDLK 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  711 VEEHIALRDELSAAAECAKGLRDELEvERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKM- 789
Cdd:TIGR00606  743 EKEIPELRNKLQKVNRDIQRLKNDIE-EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLd 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  790 RVDASMAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAEALSS-KVILAEEAK-----AIELAKKDDEMQVLS 863
Cdd:TIGR00606  822 RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSeKLQIGTNLQrrqqfEEQLVELSTEVQSLI 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  864 KEMKQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSN------KDEELKAFC 937
Cdd:TIGR00606  902 REIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgkddylKQKETELNT 981

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  938 LHEKVEREElQRQLKQEEDRCLMyKQEIVVKDKEVNFLK--MAMVAKEEEINSLMqsihsgEEKASAFQDLQEKRHEEQK 1015
Cdd:TIGR00606  982 VNAQLEECE-KHQEKINEDMRLM-RQDIDTQKIQERWLQdnLTLRKRENELKEVE------EELKQHLKEMGQMQVLQMK 1053

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1338812033 1016 QAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQER 1059
Cdd:TIGR00606 1054 QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
408-979 4.32e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  408 ERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMyEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQaLREQRVS 487
Cdd:PRK03918   193 ELIKEKEKELEEVLREINEISSELPELREELEKL-EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRE-LEERIEE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  488 LEAQIEALTADIASLTE--AVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEE 565
Cdd:PRK03918   271 LKKEIEELEEKVKELKElkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  566 AR--SNAEEWARERHEISRQQEVLMEARETIS-RERDAIATEYQHFQQEKEEVACKLnqqivlleeqqsvewsllSELRK 642
Cdd:PRK03918   351 EKrlEELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEI------------------SKITA 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  643 EKQELEQKVSSIEAIVDNLRT---RCH--GLELDSEAQR---ASHQEEVESLKRKLHEAESIlgvyEGKLADHQKIVEEH 714
Cdd:PRK03918   413 RIGELKKEIKELKKAIEELKKakgKCPvcGRELTEEHRKellEEYTAELKRIEKELKEIEEK----ERKLRKELRELEKV 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  715 IALRDELSAAAECAKGLRdELEVERSKHKetlaakLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDAS 794
Cdd:PRK03918   489 LKKESELIKLKELAEQLK-ELEEKLKKYN------LEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAEL 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  795 MAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAEalsskvilaeeaKAIELAKKDDEMQVLSKEMKQIQMELg 874
Cdd:PRK03918   562 EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYN------------EYLELKDAEKELEREEKELKKLEEEL- 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  875 tvKKAKDDMElDLQSSIEKRQEQLLVLRFQMNelEESANQKETEIEVLQTKLSNKDEELKAFclheKVEREELQRQLKQE 954
Cdd:PRK03918   629 --DKAFEELA-ETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEEL----EKRREEIKKTLEKL 699

                          570       580
                   ....*....|....*....|....*
gi 1338812033  955 EDRclmyKQEIVVKDKEVNFLKMAM 979
Cdd:PRK03918   700 KEE----LEEREKAKKELEKLEKAL 720
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1317-1606 5.36e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 5.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1317 REKLRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEkdhviktqhmeLESTVTQLKEQLHTATSLAAVQK 1396
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAE-----------LEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1397 RVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKLEHLNKWHQQQLSVLRNENQTL 1476
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1477 LSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGK 1556
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1557 KQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSEKDLA 1606
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1078-1310 7.22e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 7.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1078 KLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQ--VAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLH 1155
Cdd:COG3206    167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALR 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1156 AELKeRDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEmearhkELEESIA 1235
Cdd:COG3206    247 AQLG-SGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAA---LRAQLQQ------EAQRILA 316

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033 1236 QLQAQLGTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLL 1310
Cdd:COG3206    317 SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVI 391
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
430-671 7.27e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 7.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  430 QLQKEKKEIEMMYEVEK--TKFEAEKARLEELVsELNKMLTVQRGER-----EALEQALREQRVSLEAQIEALTADIASL 502
Cdd:COG4913    243 ALEDAREQIELLEPIRElaERYAAARERLAELE-YLRAALRLWFAQRrlellEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  503 TEAVQQRELAVtnfsQKVDVERKrvekltEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISR 582
Cdd:COG4913    322 REELDELEAQI----RGNGGDRL------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  583 QQEVLMEARETISRERDAIATEYQHFQQEKEevacklnqqivlleeqqsvewsllsELRKEKQELEQKVSSIEAIVDNLR 662
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELR-------------------------ELEAEIASLERRKSNIPARLLALR 446

                          250
                   ....*....|
gi 1338812033  663 TR-CHGLELD 671
Cdd:COG4913    447 DAlAEALGLD 456
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
201-598 1.00e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 1.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQLVQEREMRDELERELASRSQVITER--EMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKN 278
Cdd:COG4717     93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEELEERLEELRELEEELEELEAEL 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  279 EGLLTRLHDVLKQCQELKTNK-TQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRG---- 353
Cdd:COG4717    173 AELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlll 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  354 -------LLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMGPIMEWERLNQEIADlnhklSQLQE 426
Cdd:COG4717    253 liaaallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE-----ELLAA 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  427 IIIQLQKEKKEIEMMYEVEKTKFEA--------EKARLEELVSELNKMLT-VQRGEREALEQALR--EQRVSLEAQIEAL 495
Cdd:COG4717    328 LGLPPDLSPEELLELLDRIEELQELlreaeeleEELQLEELEQEIAALLAeAGVEDEEELRAALEqaEEYQELKEELEEL 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  496 TADIASLTEAVqqRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLG-----SVLNSKEEEARSNA 570
Cdd:COG4717    408 EEQLEELLGEL--EELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEedgelAELLQELEELKAEL 485

                          410       420
                   ....*....|....*....|....*...
gi 1338812033  571 EEWARERHEISRQQEVLMEARETISRER 598
Cdd:COG4717    486 RELAEEWAALKLALELLEEAREEYREER 513
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 224-798 1.18e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  224 EMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQpkEIEQLQRKNEGLLTRLHDVLKQCQ-ELKTNKTQM 302
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEVEITGLTEKASSARsQANSIQSQL 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  303 ERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEY-------LNEQIQI 375
Cdd:pfam15921  302 EIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQfsqesgnLDDQLQK 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  376 LQGKISILEDELSKAKAETLG-GGEVMGPIMEWERLNQEIADLNHKLSQLQEIiiqLQKEKKEIEMMYEVEKTKFEAEKA 454
Cdd:pfam15921  382 LLADLHKREKELSLEKEQNKRlWDRDTGNSITIDHLRRELDDRNMEVQRLEAL---LKAMKSECQGQMERQMAAIQGKNE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  455 RLEELVSELNKMLTVQRGEREALEQaLREQRVSLEAQ---IEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLT 531
Cdd:pfam15921  459 SLEKVSSLTAQLESTKEMLRKVVEE-LTAKKMTLESSertVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLK 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  532 EEMEK-------------QERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEIS------RQQEVLMEARE 592
Cdd:pfam15921  538 NEGDHlrnvqtecealklQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelQEFKILKDKKD 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  593 TISRERDAIATEyqhFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDS 672
Cdd:pfam15921  618 AKIRELEARVSD---LELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTT 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  673 ---EAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSA-------AAECAKGLRDELEVERSKH 742
Cdd:pfam15921  695 nklKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSkiqfleeAMTNANKEKHFLKEEKNKL 774

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338812033  743 KETLAAKLQSKSQMM-------EEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKL 798
Cdd:pfam15921  775 SQELSTVATEKNKMAgelevlrSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
269-694 1.28e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 1.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  269 KEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQV-- 346
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyq 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  347 EWESKRGLLES-------------ELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGggevmGPIMEWERLNQE 413
Cdd:COG4717    133 ELEALEAELAElperleeleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ-----DLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  414 IADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTK------------------FEAEKARLEELVSELNKMLTVQRGERE 475
Cdd:COG4717    208 LAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGLLA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  476 ALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEK-QERFAQKTIQELHERVDH 554
Cdd:COG4717    288 LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEElQELLREAEELEEELQLEE 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  555 LGSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQEKEEVAckLNQQIVLLEEQqsvew 634
Cdd:COG4717    368 LEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEE----- 440

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  635 slLSELRKEKQELEQKVSSIEAIVDNLRTrchglelDSEAQRASHQEevESLKRKLHEAE 694
Cdd:COG4717    441 --LEELEEELEELREELAELEAELEQLEE-------DGELAELLQEL--EELKAELRELA 489
PRK01156 PRK01156
chromosome segregation protein; Provisional
 886-1413 1.64e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 53.37  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  886 DLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKD---EELKAFCLhekvEREELQRQLKQEEDRCLMYK 962
Cdd:PRK01156   142 SLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDyleEKLKSSNL----ELENIKKQIADDEKSHSITL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  963 QEIVVKDKEVNflkmamvAKEEEINSLMQSIHsgeeKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQ 1042
Cdd:PRK01156   218 KEIERLSIEYN-------NAMDDYNNLKSALN----ELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKII 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1043 TSQVMQLQ---RDLSTEQERVVSLEQSMKVSDDAL-----IHCKLEK-EALKNEVTSLQELAEKLKGELEELKREHENLR 1113
Cdd:PRK01156   287 NDPVYKNRnyiNDYFKYKNDIENKKQILSNIDAEInkyhaIIKKLSVlQKDYNDYIKKKSRYDDLNNQILELEGYEMDYN 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1114 LQVAETETLHNKSEE-------RIAQLQARLGTASALASEKDSQLELLHAELKERD----SLRIQAAEMEARHKELEESI 1182
Cdd:PRK01156   367 SYLKSIESLKKKIEEysknierMSAFISEILKIQEIDPDAIKKELNEINVKLQDISskvsSLNQRIRALRENLDELSRNM 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1183 AQLQAR-----LGTasALASEKDSQLELLHAELKERDSLRIQAAEMEArhKELEESIAQLQAQLgtaSVLASEK------ 1251
Cdd:PRK01156   447 EMLNGQsvcpvCGT--TLGEEKSNHIINHYNEKKSRLEEKIREIEIEV--KDIDEKIVDLKKRK---EYLESEEinksin 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1252 -DSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQA-RLGTasaLASGKQSELDLL-HKEVREREKLRIRAVEVE 1328
Cdd:PRK01156   520 eYNKIESARADLED---IKIKINELKDKHDKYEEIKNRYKSlKLED---LDSKRTSWLNALaVISLIDIETNRSRSNEIK 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1329 EaQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELES----------TVTQLKEQLHTATSLAAVQKRV 1398
Cdd:PRK01156   594 K-QLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQEnkilieklrgKIDNYKKQIAEIDSIIPDLKEI 672

                          570
                   ....*....|....*
gi 1338812033 1399 NEKLNEDIRRLDVVR 1413
Cdd:PRK01156   673 TSRINDIEDNLKKSR 687
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1081-1343 1.82e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1081 KEALKNEVTSLQELAEKLKGELEELKREHEnlrlqvaetetlhnKSEERIAQLQARLGTASAlasekDSQLELLHAELKE 1160
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELE--------------EAEAALEEFRQKNGLVDL-----SEEAKLLLQQLSE 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1161 rdsLRIQAAEMEARHKELEESIAQLQARLGTASALASE--KDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQ 1238
Cdd:COG3206    224 ---LESQLAEARAELAEAEARLAALRAQLGSGPDALPEllQSPVIQQLRAQLAE---LEAELAELSARYTPNHPDVIALR 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1239 AQLgtasvlasekDSQLESLHAELKE-RDGLRIQAAEMEARHKELEESIAQLQARLGTASAlasgKQSELDLLhkevrER 1317
Cdd:COG3206    298 AQI----------AALRAQLQQEAQRiLASLEAELEALQAREASLQAQLAQLEARLAELPE----LEAELRRL-----ER 358

                          250       260
                   ....*....|....*....|....*.
gi 1338812033 1318 EklriraVEVEEAQHKELEERVTEAS 1343
Cdd:COG3206    359 E------VEVARELYESLLQRLEEAR 378
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1167-1408 2.05e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1167 QAAEMEARHKELEESIAQLQARLgtaSALASEKDSQLellhaelKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASV 1246
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKEL---AALKKEEKALL-------KQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1247 LASEKDSQLESLHAELKErdglRIQAAEMEARHKELE-----ESIAQLQARLGTASALASGKQSELDLLHKEVREREKLR 1321
Cdd:COG4942     91 EIAELRAELEAQKEELAE----LLRALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1322 iraveveeaqhKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEK 1401
Cdd:COG4942    167 -----------AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                   ....*..
gi 1338812033 1402 LNEDIRR 1408
Cdd:COG4942    236 AAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1003-1456 2.12e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1003 FQDLQEKRH--EEQKQAISTLEiRLSDAHRLLEEKASSIEMQ-----TSQVMQLQRDLSTEQERVVSLEQSMKVSDDALI 1075
Cdd:COG4913    234 FDDLERAHEalEDAREQIELLE-PIRELAERYAAARERLAELeylraALRLWFAQRRLELLEAELEELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1076 HCKLEKEALKNEVTSLQELAEKLKGE-LEELKREHENLRLQVAETETLHNKSEERIAQLQARLGT--------ASALASE 1146
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPAsaeefaalRAEAAAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1147 KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGT------------ASALaSEKDSQL----ELLhaEL 1210
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiparllalrdalAEAL-GLDEAELpfvgELI--EV 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1211 KERDS--------------LRI--------QAAE-MEARHKELEESIAQLQAQLGTASVLASEKDS---QLES------- 1257
Cdd:COG4913    470 RPEEErwrgaiervlggfaLTLlvppehyaAALRwVNRLHLRGRLVYERVRTGLPDPERPRLDPDSlagKLDFkphpfra 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1258 -LHAELKER---------------------DGLRIQAAEM-------------------EARHKELEESIAQLQARLGTA 1296
Cdd:COG4913    550 wLEAELGRRfdyvcvdspeelrrhpraitrAGQVKGNGTRhekddrrrirsryvlgfdnRAKLAALEAELAELEEELAEA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1297 SALASGKQSELDLLHKEVREREKLR--------IRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIK 1368
Cdd:COG4913    630 EERLEALEAELDALQERREALQRLAeyswdeidVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELD 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1369 tqhmELESTVTQLKEQLHTATSLaavQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEI 1448
Cdd:COG4913    710 ----ELKGEIGRLEKELEQAEEE---LDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARL 782


                   ....*...
gi 1338812033 1449 LTHTTKLE 1456
Cdd:COG4913    783 NRAEEELE 790
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 887-1297 2.17e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 52.59  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  887 LQSSIEKRQEQLLVLRFQMNELEESANQKEtEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMYKQEIV 966
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDRE-QWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKD 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  967 VKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQEKRH-------EEQKQAISTLEIRLSDAHRL---LEEKA 1036
Cdd:pfam07888  119 ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLskeFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1037 SSIEMQTSQVMQLQRDLSTEQERVVSLEQSmkvsddalihcKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQV 1116
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTLTQKLTTAHRK-----------EAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1117 AETETLHNKSEERIAQLQARLGTASALASEKDSQLEllhaelKERDSLRiQAAEMEarhkelEESIAQLQARLGTASALA 1196
Cdd:pfam07888  268 DRTQAELHQARLQAAQLTLQLADASLALREGRARWA------QERETLQ-QSAEAD------KDRIEKLSAELQRLEERL 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1197 SEKDSQLELLHAEL-KERDSLRIQAAEMEARHKELEESIAQLQaqlgtasvlasekdsqleslhaelKERDGLRiqaaem 1275
Cdd:pfam07888  335 QEERMEREKLEVELgREKDCNRVQLSESRRELQELKASLRVAQ------------------------KEKEQLQ------ 384

                          410       420
                   ....*....|....*....|..
gi 1338812033 1276 eARHKELEESIAQLQARLGTAS 1297
Cdd:pfam07888  385 -AEKQELLEYIRQLEQRLETVA 405
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1140-1348 2.26e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1140 ASALASEKDSQLELLHAEL----KERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKErds 1215
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIaeleKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE--- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1216 lriQAAEMEARHKELEESIAQLQ--AQLGTASVLASEKDSQLESLHAELKER--DGLRIQAAEMEARHKELEESIAQLQA 1291
Cdd:COG4942     95 ---LRAELEAQKEELAELLRALYrlGRQPPLALLLSPEDFLDAVRRLQYLKYlaPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033 1292 RLGTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASE 1348
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 981-1200 2.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  981 AKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSteqERV 1060
Cdd:COG4942     34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA---ELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1061 VSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTA 1140
Cdd:COG4942    111 RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1141 SALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQARLGTASALASEKD 1200
Cdd:COG4942    191 EALKAERQKLLARLEKELAE---LAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
299-511 2.88e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 52.71  E-value: 2.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  299 KTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQveweskrglLESELGQALSQKEYLNEQIQILQG 378
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD---------LSEEAKLLLQQLSELESQLAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  379 KISILEDELSKAKAETLGGGEVMGPIMEwerlnqeiadlNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEE 458
Cdd:COG3206    234 ELAEAEARLAALRAQLGSGPDALPELLQ-----------SPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAA 302

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1338812033  459 LVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEA-VQQREL 511
Cdd:COG3206    303 LRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELeAELRRL 356
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1080-1306 3.64e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 51.75  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQL-ELLHAEL 1158
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELgERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 KERDSLRIQAAEMEArhkeleESIAQLQARLGTASALASEKDSQLELLHAELKE----RDSLRIQAAEMEARHKELEESI 1234
Cdd:COG3883     97 RSGGSVSYLDVLLGS------ESFSDFLDRLSALSKIADADADLLEELKADKAEleakKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338812033 1235 AQLQAQLGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSE 1306
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAE---LEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 208-853 3.96e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 3.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  208 PQFRLRKLQKQLVQEREMRDELERELASRSQVITEREMQ--VSQLQHRVQRMMRDSEEQEQQPKEIEQLQ------RKNE 279
Cdd:TIGR00618  214 PDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQeeQLKKQQLLKQLRARIEELRAQEAVLEETQerinraRKAA 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  280 GLL---TRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQ-----KLSAEQESSQVEWESK 351
Cdd:TIGR00618  294 PLAahiKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSqeihiRDAHEVATSIREISCQ 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  352 RGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMGPIMEWERlnQEIADLNHKLSQLQEIIIQL 431
Cdd:TIGR00618  374 QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK--QQELQQRYAELCAAAITCTA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  432 QKEKKEIEMMYEV-----EKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQI------EALTADIA 500
Cdd:TIGR00618  452 QCEKLEKIHLQESaqslkEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpGPLTRRMQ 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  501 SLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNsKEEEARSNAEEWARERHEI 580
Cdd:TIGR00618  532 RGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN-ITVRLQDLTEKLSEAEDML 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  581 SRQQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQ-KVSSIEAIVD 659
Cdd:TIGR00618  611 ACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQlALQKMQSEKE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  660 NLRTRCHGLELDSEAQRASHQEEVESlKRKLHEAESILGVYEGKLAD----HQKIVEEHIALRDELSAAAECA---KGLR 732
Cdd:TIGR00618  691 QLTYWKEMLAQCQTLLRELETHIEEY-DREFNEIENASSSLGSDLAAredaLNQSLKELMHQARTVLKARTEAhfnNNEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  733 DELEVERSKHKETLAAKLQSKSQMMEEMRELEEKT-----QNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVER 807
Cdd:TIGR00618  770 VTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLeaeigQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITH 849

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1338812033  808 GLT--AARDQAFLTIKEREAETSKLRSEAEALSSKVILAEEAKAIELA 853
Cdd:TIGR00618  850 QLLkyEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFL 897
PRK09039 PRK09039
peptidoglycan -binding protein;
1145-1298 5.52e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 50.73  E-value: 5.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1145 SEKDSQLELLHAELKERDslriQAAEMEARHKE-LEESIAQLQARLGTASAlasekdsqlellhaelkERDSLRIQAAEM 1223
Cdd:PRK09039    49 SGKDSALDRLNSQIAELA----DLLSLERQGNQdLQDSVANLRASLSAAEA-----------------ERSRLQALLAEL 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1224 EARHKELEESIAQLQAQLGTASVLASEKDSQLESLH---AELKERDGlRIQAA--EMEARHKELEESIAQLQARLGTASA 1298
Cdd:PRK09039   108 AGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNqqiAALRRQLA-ALEAAldASEKRDRESQAKIADLGRRLNVALA 186
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 574-1400 6.05e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.88  E-value: 6.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  574 ARERHEISRQqevLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQS-VEW-SLLSELRKEKQELEQKV 651
Cdd:COG3096    277 ANERRELSER---ALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAaSDHlNLVQTALRQQEKIERYQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  652 SSIEAIVDNLRtrchglelDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEH----IALRDELSAAAEc 727
Cdd:COG3096    354 EDLEELTERLE--------EQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQqtraIQYQQAVQALEK- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  728 AKGL--RDELEVERSK-HKETLAAKLQSKSQmmeemreleektqnmsvEMQHLGQQLSKVQQEKMRVDASMAKLIEEGRE 804
Cdd:COG3096    425 ARALcgLPDLTPENAEdYLAAFRAKEQQATE-----------------EVLELEQKLSVADAARRQFEKAYELVCKIAGE 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  805 VERGltaardQAFLTIKEREAETSKLRSEAEALSS--------KVILAEEAKAIELAKkddEMQVLSKEMKQIQMELGTV 876
Cdd:COG3096    488 VERS------QAWQTARELLRRYRSQQALAQRLQQlraqlaelEQRLRQQQNAERLLE---EFCQRIGQQLDAAEELEEL 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  877 KKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQ---KETEIEVLQTKLSNKDEELKAF---------CLHEKVER 944
Cdd:COG3096    559 LAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKElaaRAPAWLAAQDALERLREQSGEAladsqevtaAMQQLLER 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  945 EelqRQLKQEEDRCLMYKQEIvvkDKEVNFLKMAMVAKEEEINSLMQSIhSGEEKASAFQDLQ-------EKRHEEQKQA 1017
Cdd:COG3096    639 E---REATVERDELAARKQAL---ESQIERLSQPGGAEDPRLLALAERL-GGVLLSEIYDDVTledapyfSALYGPARHA 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1018 ISTLEirLSDAHRLLEEKASSIEmqtsQVMQLQRDLSTEQERVVSLEQS-----MKVSDDALIHCKLEKEALKNEVTSLQ 1092
Cdd:COG3096    712 IVVPD--LSAVKEQLAGLEDCPE----DLYLIEGDPDSFDDSVFDAEELedavvVKLSDRQWRYSRFPEVPLFGRAAREK 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1093 ELaEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQlqarlGTASALASEKDSQLELLHAELKERDSLRIQAAEME 1172
Cdd:COG3096    786 RL-EELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVGG-----HLAVAFAPDPEAELAALRQRRSELERELAQHRAQE 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1173 ARHKE----LEESIAQLQARLGTASALASEKDSQ-LELLHAELKERDSLRIQAAEMEARHKELE----------ESIAQL 1237
Cdd:COG3096    860 QQLRQqldqLKEQLQLLNKLLPQANLLADETLADrLEELREELDAAQEAQAFIQQHGKALAQLEplvavlqsdpEQFEQL 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1238 QAQLGTASVLASEKDSQLESLhAELKER--------------------DGLRIQAAEMEARHKELEESIAQLQARLGTA- 1296
Cdd:COG3096    940 QADYLQAKEQQRRLKQQIFAL-SEVVQRrphfsyedavgllgensdlnEKLRARLEQAEEARREAREQLRQAQAQYSQYn 1018

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1297 ---SALASGKQSELDLLHKEVREREKLRIRA-VEVEEAQHKELEERVTEASTLASERKS---QLDSLHNEMNEkdhvIKT 1369
Cdd:COG3096   1019 qvlASLKSSRDAKQQTLQELEQELEELGVQAdAEAEERARIRRDELHEELSQNRSRRSQlekQLTRCEAEMDS----LQK 1094

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1338812033 1370 QHMELESTVTQLKEQLHTA-TSLAAVQKRVNE 1400
Cdd:COG3096   1095 RLRKAERDYKQEREQVVQAkAGWCAVLRLARD 1126
mukB PRK04863
chromosome partition protein MukB;
1005-1343 6.97e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.50  E-value: 6.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1005 DLQEK--RHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKE 1082
Cdd:PRK04863   356 DLEELeeRLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCGLPDL 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1083 ALKNEVTSLQELAEKLKgELEELKREHENlRLQVAETetlHNKSEERIAQLQARLGTASALASEKDSQLELLhaelKERD 1162
Cdd:PRK04863   436 TADNAEDWLEEFQAKEQ-EATEELLSLEQ-KLSVAQA---AHSQFEQAYQLVRKIAGEVSRSEAWDVARELL----RRLR 506

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1163 SLRIQAAE---MEARHKELEESIAQLQarlgtasalasekdsQLELLHAELKERDSLRIQAAEmearhkELEESIAQLQA 1239
Cdd:PRK04863   507 EQRHLAEQlqqLRMRLSELEQRLRQQQ---------------RAERLLAEFCKRLGKNLDDED------ELEQLQEELEA 565

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1240 QLGTASVLASEKDSQLESLHAELKErdgLRIQAAEMEARHKE---LEESIAQLQARLGtaSALASGKQseLDLLHKEVRE 1316
Cdd:PRK04863   566 RLESLSESVSEARERRMALRQQLEQ---LQARIQRLAARAPAwlaAQDALARLREQSG--EEFEDSQD--VTEYMQQLLE 638

                          330       340
                   ....*....|....*....|....*..
gi 1338812033 1317 REKLRIRAVEVEEAQHKELEERVTEAS 1343
Cdd:PRK04863   639 RERELTVERDELAARKQALDEEIERLS 665
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 416-953 7.15e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 7.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  416 DLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEA- 494
Cdd:pfam05483  212 EMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKk 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  495 --LTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKT-------IQELHERVDHLGSVLNSKEEE 565
Cdd:pfam05483  292 dhLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQR 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  566 ARSNAEEWA-------------RERHEISRQQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQ-- 630
Cdd:pfam05483  372 LEKNEDQLKiitmelqkksselEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREke 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  631 ------------SVEWSLLSELRKEKQELE-QKVSSIEaivdnLRTRCHGLELDSEAQRASHQEEVESLKRKLHEAESIL 697
Cdd:pfam05483  452 ihdleiqltaikTSEEHYLKEVEDLKTELEkEKLKNIE-----LTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCK 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  698 GVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHL 777
Cdd:pfam05483  527 KQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  778 GQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAE--ALSSKVILAEEAKAIELAkk 855
Cdd:pfam05483  607 NKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEdkKISEEKLLEEVEKAKAIA-- 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  856 dDEMQVLSKEM-KQIQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELK 934
Cdd:pfam05483  685 -DEAVKLQKEIdKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLE 763

                          570
                   ....*....|....*....
gi 1338812033  935 AfclhEKVEREELQRQLKQ 953
Cdd:pfam05483  764 I----EKEEKEKLKMEAKE 778
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1008-1293 8.13e-06

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 50.45  E-value: 8.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1008 EKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQsmkvsddalihcklEKEALKNE 1087
Cdd:pfam19220   82 EGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEE--------------ENKALREE 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1088 VTSLQELAEKLKGELEELKR-----EHENLRLQ----------------VAETETLHNKSEERIAQLQARLGTASALASE 1146
Cdd:pfam19220  148 AQAAEKALQRAEGELATARErlallEQENRRLQalseeqaaelaeltrrLAELETQLDATRARLRALEGQLAAEQAERER 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1147 KDSQLELLHAELK-ERDSLRIQAAEMEARHKELEESIAQLQARLGtasalasEKDSQLELLHAELKErdsLRIQAAEMEA 1225
Cdd:pfam19220  228 AEAQLEEAVEAHRaERASLRMKLEALTARAAATEQLLAEARNQLR-------DRDEAIRAAERRLKE---ASIERDTLER 297

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033 1226 RHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKERDglrIQAAEMEARHKELEESIAQLQARL 1293
Cdd:pfam19220  298 RLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKD---AALERAEERIASLSDRIAELTKRF 362
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 209-691 8.43e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 8.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  209 QFRLRKLQKQLVQEREMR-----DELERELasrsqviTEREMQVSQLQHRVQRMmrDSEEQEQQPKEIEQLQRKNEGL-- 281
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGnsitiDHLRREL-------DDRNMEVQRLEALLKAM--KSECQGQMERQMAAIQGKNESLek 462

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  282 -------LTRLHDVLKQC-QELKTNKTQME---RKIDDLTEengilSVQMREifSRLSSAEAAVQKLSAEQESSQVEWES 350
Cdd:pfam15921  463 vssltaqLESTKEMLRKVvEELTAKKMTLEsseRTVSDLTA-----SLQEKE--RAIEATNAEITKLRSRVDLKLQELQH 535

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  351 KRGlLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGGEVMGPI-MEWERLNQEIADLNHKLSQLqeiii 429
Cdd:pfam15921  536 LKN-EGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqVEKAQLEKEINDRRLELQEF----- 609

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  430 QLQKEKKEiemmyevekTKFEAEKARLEELvsELNKMLTVQRG-EREALEQALREQRVSLEAQIEALTADIASLTEavqQ 508
Cdd:pfam15921  610 KILKDKKD---------AKIRELEARVSDL--ELEKVKLVNAGsERLRAVKDIKQERDQLLNEVKTSRNELNSLSE---D 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  509 RELAVTNFSQKvdveRKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLM 588
Cdd:pfam15921  676 YEVLKRNFRNK----SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  589 EARETISRerdaiATEYQHFQQEKEEvacKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRChgl 668
Cdd:pfam15921  752 FLEEAMTN-----ANKEKHFLKEEKN---KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQF--- 820

                          490       500
                   ....*....|....*....|...
gi 1338812033  669 eldSEAQRASHQEEVESLKRKLH 691
Cdd:pfam15921  821 ---AECQDIIQRQEQESVRLKLQ 840
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 355-928 8.92e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 8.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  355 LESELGQALSQKEYLNEQIQILQGKIS-----------------------------------ILEDELSKAKAETLGGGE 399
Cdd:TIGR04523   59 LDKNLNKDEEKINNSNNKIKILEQQIKdlndklkknkdkinklnsdlskinseikndkeqknKLEVELNKLEKQKKENKK 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  400 VMGPIM-EWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEmmYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALE 478
Cdd:TIGR04523  139 NIDKFLtEIKKKEKELEKLNNKYNDLKKQKEELENELNLLE--KEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSL 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  479 QA----LREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQErfaqKTIQELHERVDH 554
Cdd:TIGR04523  217 ESqiseLKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNN----KKIKELEKQLNQ 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  555 LGSVL----NSKE--------EEARSNAEEWARERHEISRQQEVLMEARETIS---RERDAIATEYQHFQQEKEEvacKL 619
Cdd:TIGR04523  293 LKSEIsdlnNQKEqdwnkelkSELKNQEKKLEEIQNQISQNNKIISQLNEQISqlkKELTNSESENSEKQRELEE---KQ 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  620 NQQIVLLEEQQSVEWSLLSeLRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEaqraSHQEEVESLKRKLHEAESILGV 699
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKE----LLEKEIERLKETIIKNNSEIKD 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  700 YEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQ 779
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKE 524

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  780 QLSKVQQEKMRVDASMAKLIEEGREVERGLTaaRDQAFLTIKEREAETSKLRSEAEAL-SSKVILAEEAKAIELAKKDDE 858
Cdd:TIGR04523  525 KIEKLESEKKEKESKISDLEDELNKDDFELK--KENLEKEIDEKNKEIEELKQTQKSLkKKQEEKQELIDQKEKEKKDLI 602

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033  859 MQVLSKEMKQIQM--ELGTVKKAKDDMEL---DLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSN 928
Cdd:TIGR04523  603 KEIEEKEKKISSLekELEKAKKENEKLSSiikNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
PLN02939 PLN02939
transferase, transferring glycosyl groups
 236-656 9.02e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.06  E-value: 9.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  236 RSQVITEREMQVSQlqhRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQcQELKTNKTQMERKIDDLTEENGI 315
Cdd:PLN02939    22 PFYLPSRRRLAVSC---RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQ-LENTSLRTVMELPQKSTSSDDDH 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  316 LSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRG----------LLESELGQALSQKEYLNEQIQILQGKISILED 385
Cdd:PLN02939    98 NRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGmiqnaeknilLLNQARLQALEDLEKILTEKEALQGKINILEM 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  386 ELSKAKAET-LGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEElVSELN 464
Cdd:PLN02939   178 RLSETDARIkLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIE-VAETE 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  465 KMLTVQRGEREALEQALREqrvsLEAQIEALTADIASLTeavqqrelavtnfSQKVDVERKRVEKLTEEMEKQERFAQKT 544
Cdd:PLN02939   257 ERVFKLEKERSLLDASLRE----LESKFIVAQEDVSKLS-------------PLQYDCWWEKVENLQDLLDRATNQVEKA 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  545 I------QELHERVDHLgsvlnsKEEEARSNAEEWARERHEISRQQEVLMEAR-ETISRERDAIATEYQHFQQEKEEVAC 617
Cdd:PLN02939   320 AlvldqnQDLRDKVDKL------EASLKEANVSKFSSYKVELLQQKLKLLEERlQASDHEIHSYIQLYQESIKEFQDTLS 393

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1338812033  618 KLNQQIVLLEEQQSVE------WSLLSeLRKEKQELEQKVSSIEA 656
Cdd:PLN02939   394 KLKEESKKRSLEHPADdmpsefWSRIL-LLIDGWLLEKKISNNDA 437
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 323-539 1.06e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  323 IFSRLSSAEAAVQKLSAEQESSQVEWESKRGLL---ESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETlggge 399
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELaalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL----- 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  400 vmgpimewERLNQEIADLNHKLSQLQEIIIQL------------------QKEKKEIEMMYEVEKTKFEAEKARLEEL-- 459
Cdd:COG4942     86 --------AELEKEIAELRAELEAQKEELAELlralyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELra 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  460 ----VSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEME 535
Cdd:COG4942    158 dlaeLAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                   ....
gi 1338812033  536 KQER 539
Cdd:COG4942    238 AAAE 241
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
519-1128 1.22e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  519 KVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEArsnaeewarERHEISRQQevlmeARETISrER 598
Cdd:PRK02224   175 RLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEI---------ERYEEQREQ-----ARETRD-EA 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  599 DAIATEYQHFQQEKEEvackLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQrAS 678
Cdd:PRK02224   240 DEVLEEHEERREELET----LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAV-EA 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  679 HQEEVESLKRKLHEAesilgvYEGKLADHQKIVEEHIALRDELSAAAECAKGLR---DELEVERSKHKETLAAKLQSKSQ 755
Cdd:PRK02224   315 RREELEDRDEELRDR------LEECRVAAQAHNEEAESLREDADDLEERAEELReeaAELESELEEAREAVEDRREEIEE 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  756 MMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARD-----------------QAFL 818
Cdd:PRK02224   389 LEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgqpvegsPHVE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  819 TIKEREAETSKLRSEAEALsskvilaeEAKAIELAKKDDEMQVLSKEMKQIQmELGTVKKAKDDMELDLQSSIEKRQEQL 898
Cdd:PRK02224   469 TIEEDRERVEELEAELEDL--------EEEVEEVEERLERAEDLVEAEDRIE-RLEERREDLEELIAERRETIEEKRERA 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  899 LVLRFQMNELEESANQKEteiEVLQTKLSNKDEelkafCLHEKVEREELQRQLKQEEDRClmykqeivvkdkevnflkMA 978
Cdd:PRK02224   540 EELRERAAELEAEAEEKR---EAAAEAEEEAEE-----AREEVAELNSKLAELKERIESL------------------ER 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  979 MVAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQaistleirLSDAHRLLEEkassiEMQTSQVMQLQRDLSTeqe 1058
Cdd:PRK02224   594 IRTLLAAIADAEDEIERLREKREALAELNDERRERLAE--------KRERKRELEA-----EFDEARIEEAREDKER--- 657

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1059 rvvsLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEklkgELEELKREHENLRLQVAETETLHNKSEE 1128
Cdd:PRK02224   658 ----AEEYLEQVEEKLDELREERDDLQAEIGAVENELE----ELEELRERREALENRVEALEALYDEAEE 719
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
201-596 1.24e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQLVQEREMR---DELERELASRSQVITEREMQVS-QLQHRVQRMMRDSEEQEQQPKEIEQLQR 276
Cdd:COG4717    137 LEAELAELPERLEELEERLEELRELEeelEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELE 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  277 KNEGLLTRLHDVLKQCQELKTNKtQMERKIDDLTeengilsvQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLE 356
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAA-ALEERLKEAR--------LLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLA 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  357 SELGQALSQKEYLNEQIQILQG--KISILEDELSKAKAETLGGGEVMGPImEWERLNQEIADLNHKLSQLQEII--IQLQ 432
Cdd:COG4717    288 LLFLLLAREKASLGKEAEELQAlpALEELEEEELEELLAALGLPPDLSPE-ELLELLDRIEELQELLREAEELEeeLQLE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  433 KEKKEIEMMYEVEKTKFEAEKARLEELVSELNKmltvQRGEREALEQALREQRVSLEAQIEALTADiaSLTEAVQQRELA 512
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQE----LKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  513 VTNFSQKVDVERKRVEKLTEEMEKQERfaQKTIQELHERVDHLGSVLNSKEEEARSN--AEEW---ARERHEISRQQEVL 587
Cdd:COG4717    441 LEELEEELEELREELAELEAELEQLEE--DGELAELLQELEELKAELRELAEEWAALklALELleeAREEYREERLPPVL 518


                   ....*....
gi 1338812033  588 MEARETISR 596
Cdd:COG4717    519 ERASEYFSR 527
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1080-1302 1.37e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.83  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1080 EKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLhAELK 1159
Cdd:COG3883     31 ELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYL-DVLL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1160 ERDSL-----RIQAAE-MEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKErdslriQAAEMEARHKELEES 1233
Cdd:COG3883    110 GSESFsdfldRLSALSkIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEA------AKAELEAQQAEQEAL 183

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033 1234 IAQLQAQLGTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASG 1302
Cdd:COG3883    184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAA 252
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 421-1318 1.47e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.43  E-value: 1.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  421 LSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLT----VQRGEREALEQALREQRVS-LEAQIEAL 495
Cdd:TIGR00606  188 LETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESsreiVKSYENELDPLKNRLKEIEhNLSKIMKL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  496 TADIASLTEAVQQRELAVTNFSQKVDverKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWAR 575
Cdd:TIGR00606  268 DNEIKALKSRKKQMEKDNSELELKME---KVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  576 ERHEISRQQeVLMEARETISRERDAIATEYQ-HFQQEKEEVACKLNQQI----VLLEEQQSVEWSLLSELrkeKQELEQK 650
Cdd:TIGR00606  345 LLVEQGRLQ-LQADRHQEHIRARDSLIQSLAtRLELDGFERGPFSERQIknfhTLVIERQEDEAKTAAQL---CADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  651 VSSIEAIVDNLRTRCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIAL-RDELSAAAECAK 729
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELsKAEKNSLTETLK 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  730 GLRDELEVERSKHKETLAaKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGL 809
Cdd:TIGR00606  501 KEVKSLQNEKADLDRKLR-KLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  810 TAARDQAFLTiKEREAETSKLRSEAEALSSKVILAEEAKAIELAKKDDEM-QVLSKEMKQIQMElgtvkkakddmelDLQ 888
Cdd:TIGR00606  580 HSKSKEINQT-RDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfDVCGSQDEESDLE-------------RLK 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  889 SSIEKRQEQLLVLRFQMNE----LEESANQKETEIEVLQTKLSNKDE------ELKAFCLHEKVEREELQRQLKQEEDR- 957
Cdd:TIGR00606  646 EEIEKSSKQRAMLAGATAVysqfITQLTDENQSCCPVCQRVFQTEAElqefisDLQSKLRLAPDKLKSTESELKKKEKRr 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  958 ------CLMYKQEIVVKDKEVNFLKmamvAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIrLSDAHRL 1031
Cdd:TIGR00606  726 demlglAPGRQSIIDLKEKEIPELR----NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTI-MERFQME 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1032 LEEKASSIEMQTSQVMQLQRDLSTEQervvsLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHEN 1111
Cdd:TIGR00606  801 LKDVERKIAQQAAKLQGSDLDRTVQQ-----VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQ 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1112 LRLQVAETETLHNKSEERIAQLQArLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESI--AQLQARL 1189
Cdd:TIGR00606  876 IGTNLQRRQQFEEQLVELSTEVQS-LIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDikEKVKNIH 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1190 GTASALASE-KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLAS---------EKDSQLESLH 1259
Cdd:TIGR00606  955 GYMKDIENKiQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnltlrKRENELKEVE 1034

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1260 AELKERDGL--RIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVRERE 1318
Cdd:TIGR00606 1035 EELKQHLKEmgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 319-519 1.64e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.44  E-value: 1.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  319 QMREIFSRLSSAEAAVQKLSAEQESSQVEWESkrglLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGG 398
Cdd:COG3883     24 ELSELQAELEAAQAELDALQAELEELNEEYNE----LQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSG 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  399 EVMGP-------------IMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMmyevEKTKFEAEKARLEELVSELNK 465
Cdd:COG3883    100 GSVSYldvllgsesfsdfLDRLSALSKIADADADLLEELKADKAELEAKKAELEA----KLAELEALKAELEAAKAELEA 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1338812033  466 mltvQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQK 519
Cdd:COG3883    176 ----QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
487-723 1.77e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  487 SLEAQIEALTADIASLTEAvqqRELAVTnfsqkvdvERKRVEKLTEEMEKQERFAQKTIQelHERVDHLGSVLNSKEEEA 566
Cdd:COG4913    222 DTFEAADALVEHFDDLERA---HEALED--------AREQIELLEPIRELAERYAAARER--LAELEYLRAALRLWFAQR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  567 RsnAEEWARERHEISRQQEVLMEARETISRERDAIATEYQhfqqekeevacklnqqiVLLEEQQSVEWSLLSELRKEKQE 646
Cdd:COG4913    289 R--LELLEAELEELRAELARLEAELERLEARLDALREELD-----------------ELEAQIRGNGGDRLEQLEREIER 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  647 LEQKVSSIEAIVDNLRTRCHGLEL---DSEAQRASHQEEVESLKRKLHEAESILGVYEGKL-ADHQKIVEEHIALRDELS 722
Cdd:COG4913    350 LERELEERERRRARLEALLAALGLplpASAEEFAALRAEAAALLEALEEELEALEEALAEAeAALRDLRRELRELEAEIA 429


                   .
gi 1338812033  723 A 723
Cdd:COG4913    430 S 430
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 830-1435 1.90e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.95  E-value: 1.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  830 LRSEAEALSSKVILAEE-AKAIELAKKDDEMQVLSKEMKQ-IQM---ELGTVKKAkddmeLDLQSSIEKRQEQLLVLRFQ 904
Cdd:COG3096    288 LELRRELFGARRQLAEEqYRLVEMARELEELSARESDLEQdYQAasdHLNLVQTA-----LRQQEKIERYQEDLEELTER 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  905 MNELEESANQKETEIEVLQTKLSNKDEELKAFclheKVEREELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKM------- 977
Cdd:COG3096    363 LEEQEEVVEEAAEQLAEAEARLEAAEEEVDSL----KSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLpdltpen 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  978 ------AMVAKEEEINS------------------------LMQSIHSGEEKASAFQDLQE--KRHEEQK---QAISTLE 1022
Cdd:COG3096    439 aedylaAFRAKEQQATEevleleqklsvadaarrqfekayeLVCKIAGEVERSQAWQTAREllRRYRSQQalaQRLQQLR 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1023 IRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSmkvsddalihcKLEKEALKNEVTSLQELAEKLKGEL 1102
Cdd:COG3096    519 AQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAEL-----------EAQLEELEEQAAEAVEQRSELRQQL 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1103 EELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDslriqaaEMEARHKELEESI 1182
Cdd:COG3096    588 EQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERD-------ELAARKQALESQI 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1183 AQLQARLGTASA-LASEKDSQLELLHAELKERDSLRiQAAEMEA-----RH----KELEESIAQLQA------------- 1239
Cdd:COG3096    661 ERLSQPGGAEDPrLLALAERLGGVLLSEIYDDVTLE-DAPYFSAlygpaRHaivvPDLSAVKEQLAGledcpedlylieg 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1240 --QLGTASVLASE------------------------------KDSQLESLHAelkERDGLRIQAAEMEARHKELEESIA 1287
Cdd:COG3096    740 dpDSFDDSVFDAEeledavvvklsdrqwrysrfpevplfgraaREKRLEELRA---ERDELAEQYAKASFDVQKLQRLHQ 816

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1288 QLQARLGTASALASGKQSELDLlhKEVREreklRIRAVEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMN--EKDH 1365
Cdd:COG3096    817 AFSQFVGGHLAVAFAPDPEAEL--AALRQ----RRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANllADET 890

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1366 viktqhmeLESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRK 1435
Cdd:COG3096    891 --------LADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRR 952
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 897-1439 2.01e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 49.74  E-value: 2.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  897 QLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRcLMYKQEIVVKDKEVNFLK 976
Cdd:pfam05557    3 ELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKR-EAEAEEALREQAELNRLK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  977 MamvAKEEEINSLMQSIHSGEEKASAFQD-----LQEKRH--EEQKQAISTLEI---RLSDAHRLLEEKASSIEMQTSQV 1046
Cdd:pfam05557   82 K---KYLEALNKKLNEKESQLADAREVISclkneLSELRRqiQRAELELQSTNSeleELQERLDLLKAKASEAEQLRQNL 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1047 MQLQRDLSTEQERVVSLEQSMKVSDDAlihcKLEKEALKNEVTSLQElaekLKGELEELKREHENLRLQVAETETLhnks 1126
Cdd:pfam05557  159 EKQQSSLAEAEQRIKELEFEIQSQEQD----SEIVKNSKSELARIPE----LEKELERLREHNKHLNENIENKLLL---- 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1127 EERIAQLQARLGTASALASEKDS-QLELLH--AELKERDSLrIQAAEMEARHKE-LEESIAQLQARLGTASALASEKDSQ 1202
Cdd:pfam05557  227 KEEVEDLKRKLEREEKYREEAATlELEKEKleQELQSWVKL-AQDTGLNLRSPEdLSRRIEQLQQREIVLKEENSSLTSS 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1203 LELLHAELK----ERDSLRIQAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKERD-----GLRIQAA 1273
Cdd:pfam05557  306 ARQLEKARReleqELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNyspqlLERIEEA 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1274 E-----MEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEV---------REREKLRiRAVEVEEAQHKELEERV 1339
Cdd:pfam05557  386 EdmtqkMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQEsladpsyskEEVDSLR-RKLETLELERQRLREQK 464

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1340 TEASTLASERKSQLDS-------LHNEMN---EKDHVIKTQHMELESTVTQLKEQLhtatslaavqkRVNEKLNEDIRRL 1409
Cdd:pfam05557  465 NELEMELERRCLQGDYdpkktkvLHLSMNpaaEAYQQRKNQLEKLQAEIERLKRLL-----------KKLEDDLEQVLRL 533

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1338812033 1410 DVVRQESMERDALRIRA-IEAEDLKRKEMEE 1439
Cdd:pfam05557  534 PETTSTMNFKEVLDLRKeLESAELKNQRLKE 564
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 636-1350 2.15e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.72  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  636 LLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQRASHQE---EVESLKRKLHEaesilGVYEGKLADHQKIVE 712
Cdd:pfam05483   79 LYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEE-----EIQENKDLIKENNAT 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  713 EHIA--LRDELSAAAECAKGLRDELEVERSKH-------KETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSK 783
Cdd:pfam05483  154 RHLCnlLKETCARSAEKTKKYEYEREETRQVYmdlnnniEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  784 VQQEKMRVDASMAKLIEEGREVERGLTAARDQAFLTIKEREaETSKLRSE--AEALSSKVILAEEAKAIELAKK------ 855
Cdd:pfam05483  234 EINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLE-EKTKLQDEnlKELIEKKDHLTKELEDIKMSLQrsmstq 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  856 ---DDEMQVLSK------EMKQIQME-LGTVKKAKDDMELDLQSSIEKRQEqllVLRFQMNELEESANQKETEIEVLQTK 925
Cdd:pfam05483  313 kalEEDLQIATKticqltEEKEAQMEeLNKAKAAHSFVVTEFEATTCSLEE---LLRTEQQRLEKNEDQLKIITMELQKK 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  926 lSNKDEELKAFCLHEKVEREELQRQLKQeedrclmyKQEIVVKDKEVNFLKMAMVAKEEEINSLMQS----IHSGEEKAS 1001
Cdd:pfam05483  390 -SSELEEMTKFKNNKEVELEELKKILAE--------DEKLLDEKKQFEKIAEELKGKEQELIFLLQArekeIHDLEIQLT 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1002 AFQDLQEKRHEEQKQAISTLEirlsdahrllEEKASSIEMQTSQVMQLQRDLSTEQErVVSLEQSMKVSDDALIHCKLEK 1081
Cdd:pfam05483  461 AIKTSEEHYLKEVEDLKTELE----------KEKLKNIELTAHCDKLLLENKELTQE-ASDMTLELKKHQEDIINCKKQE 529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1082 EALKNEVTSLQELAEKLKGELEELKREhenLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKER 1161
Cdd:pfam05483  530 ERMLKQIENLEEKEMNLRDELESVREE---FIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK 606

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1162 DSlriQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKE-RDSLRIQAAEMEARHKELEESIAQLQAQ 1240
Cdd:pfam05483  607 NK---NIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEiIDNYQKEIEDKKISEEKLLEEVEKAKAI 683

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1241 LGTASVLASEKDSQLESLHAELkerdglriqAAEMEARHKELEESIAQLQARLG-------TASALASGKQSELDLLHKE 1313
Cdd:pfam05483  684 ADEAVKLQKEIDKRCQHKIAEM---------VALMEKHKHQYDKIIEERDSELGlyknkeqEQSSAKAALEIELSNIKAE 754

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 1338812033 1314 VREREKlrirAVEVEEAQHKELEERVTEASTLASERK 1350
Cdd:pfam05483  755 LLSLKK----QLEIEKEEKEKLKMEAKENTAILKDKK 787
PRK12704 PRK12704
phosphodiesterase; Provisional
 1081-1236 2.27e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.39  E-value: 2.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1081 KEAlKNEVTSLQELAE-KLKGELEELKREHENlrlQVAETETLHNKSEERIAQLQARLgtasalaSEKDSQLELLHAEL- 1158
Cdd:PRK12704    45 EEA-KKEAEAIKKEALlEAKEEIHKLRNEFEK---ELRERRNELQKLEKRLLQKEENL-------DRKLELLEKREEELe 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1159 KERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASE--KDSQLELLHAELKERDSLRIQAAEMEAR---HKELEES 1233
Cdd:PRK12704   114 KKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEEEARHEAAVLIKEIEEEAKeeaDKKAKEI 193


                   ...
gi 1338812033 1234 IAQ 1236
Cdd:PRK12704   194 LAQ 196
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 186-930 2.29e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 2.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  186 FLELKTVASSSVGSPIQDVLNTPQFRLRKLQKQLVQEREMRDELERELASRSQVITEREMQ----VSQLQHRVQRMMRDS 261
Cdd:TIGR00606  395 FHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvIKELQQLEGSSDRIL 474

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  262 EEQEQQPKEIEQLQRKNEGLLTRLhdVLKQCQELKTNKTQMERKIDDLTEENGILSvqmREIFSRLSSAEAAVQKLSAEQ 341
Cdd:TIGR00606  475 ELDQELRKAERELSKAEKNSLTET--LKKEVKSLQNEKADLDRKLRKLDQEMEQLN---HHTTTRTQMEMLTKDKMDKDE 549

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  342 ESSQVEWESKRGLLeSELGQaLSQKEYLNEQIQILQGKISILEDELSKakaetlgggevmgpimewerLNQEIAdlnhKL 421
Cdd:TIGR00606  550 QIRKIKSRHSDELT-SLLGY-FPNKKQLEDWLHSKSKEINQTRDRLAK--------------------LNKELA----SL 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  422 SQLQEIIIQLQKEKKEIEMMYE---VEKTKFEAEKARLEELVSELNKmltvQRGEREALEQALREQRVSLEaQIEALTAD 498
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSSYEdklFDVCGSQDEESDLERLKEEIEK----SSKQRAMLAGATAVYSQFIT-QLTDENQS 678

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  499 IASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEA-------RSNAE 571
Cdd:TIGR00606  679 CCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIpelrnklQKVNR 758

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  572 EWARERHEISRQQEVL--MEARETISRERDAIATEYQHFQQEKEEVACKLNQQIvllEEQQSVEWSL-LSELRKEKQELE 648
Cdd:TIGR00606  759 DIQRLKNDIEEQETLLgtIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQA---AKLQGSDLDRtVQQVNQEKQEKQ 835

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  649 QKVSSIEAIVDNLRtRCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEhiaLRDELSAAAECA 728
Cdd:TIGR00606  836 HELDTVVSKIELNR-KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQS---LIREIKDAKEQD 911

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  729 KGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSK-VQQEKMRVDASMAKLIEEGREVEr 807
Cdd:TIGR00606  912 SPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETELNTVNAQLEECE- 990

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  808 gltaardqafltiKEREAETSKLRSEAEALSSKVILAEEAK-AIELAKKDDEMQVLSKEMKQIQMELGtvkkakDDMELD 886
Cdd:TIGR00606  991 -------------KHQEKINEDMRLMRQDIDTQKIQERWLQdNLTLRKRENELKEVEEELKQHLKEMG------QMQVLQ 1051

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1338812033  887 LQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNKD 930
Cdd:TIGR00606 1052 MKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
375-585 2.31e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  375 ILQGKISILEDELSKAKAE--TLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMyevektkfEAE 452
Cdd:COG4717     39 LLAFIRAMLLERLEKEADElfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL--------EAE 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  453 KARLEELVSELNKMLTVQRGEREalEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTE 532
Cdd:COG4717    111 LEELREELEKLEKLLQLLPLYQE--LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSL 188

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1338812033  533 EMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQE 585
Cdd:COG4717    189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL 241
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 736-1383 2.56e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 2.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  736 EVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQH-LGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARD 814
Cdd:TIGR00618  185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEkELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQ 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  815 QA--FLTIKEREAETSKLRSEAEALSSKVILAEEAKAIELAKKD-----DEMQVLSKEMKQIQMELGTVKKAKDDMElDL 887
Cdd:TIGR00618  265 LRarIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQaqrihTELQSKMRSRAKLLMKRAAHVKQQSSIE-EQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  888 QSSIEKRQEQLLVLRFQMNE----LEESANQKETE--IEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEEDRCLMY 961
Cdd:TIGR00618  344 RRLLQTLHSQEIHIRDAHEVatsiREISCQQHTLTqhIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQ 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  962 KQEIVVKDKEVNFLKMAM---VAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASS 1038
Cdd:TIGR00618  424 GQLAHAKKQQELQQRYAElcaAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEP 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1039 IEMQTS-----QVMQLQRDLSTEQERVVSLEQSMKVSDDALihcklekEALKNEVTSLQELAEKLKGELEELKREHENLR 1113
Cdd:TIGR00618  504 CPLCGScihpnPARQDIDNPGPLTRRMQRGEQTYAQLETSE-------EDVYHQLTSERKQRASLKEQMQEIQQSFSILT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1114 LQVAETETLHNKSEERIAQLQARLgtaSALASEKDSQLELLHAELKErdsLRIQAAEMEARHKE--LEESIAQLQARL-G 1190
Cdd:TIGR00618  577 QCDNRSKEDIPNLQNITVRLQDLT---EKLSEAEDMLACEQHALLRK---LQPEQDLQDVRLHLqqCSQELALKLTALhA 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1191 TASALASEKDSQLELLHAELKERDSLRIQAAEMEARHK---------ELEESIAQLQAQ---LGTASVLASEKDSQLESL 1258
Cdd:TIGR00618  651 LQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEkeqltywkeMLAQCQTLLRELethIEEYDREFNEIENASSSL 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1259 HAELKERDGLR---IQAAEMEARHKELEESIAQLQARLGTASALASGKQ-SELDLLHKEVREREKLRIRAVEVEEAQHKE 1334
Cdd:TIGR00618  731 GSDLAAREDALnqsLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAElSHLAAEIQFFNRLREEDTHLLKTLEAEIGQ 810

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1338812033 1335 -----LEERVTEASTLASERKsQLDSLHNEMNEKDHVIKTQHMELESTVTQLKE 1383
Cdd:TIGR00618  811 eipsdEDILNLQCETLVQEEE-QFLSRLEEKSATLGEITHQLLKYEECSKQLAQ 863
mukB PRK04863
chromosome partition protein MukB;
1147-1465 2.75e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.57  E-value: 2.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1147 KDSQLELLHAElkeRDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKD--SQLELLHAELKERDSL--RIQAAE 1222
Cdd:PRK04863   784 REKRIEQLRAE---REELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAFEADpeAELRQLNRRRVELERAlaDHESQE 860

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1223 MEARH--KELEESIAQLQAQLGTASVLASEK-DSQLESLHAELKERDglriQAAEMEARHKELEESIAQLQARLGTasal 1299
Cdd:PRK04863   861 QQQRSqlEQAKEGLSALNRLLPRLNLLADETlADRVEEIREQLDEAE----EAKRFVQQHGNALAQLEPIVSVLQS---- 932

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1300 asgKQSELDLLHKEVREREKLRIRAveveEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKdhvIKTQHMELESTVT 1379
Cdd:PRK04863   933 ---DPEQFEQLKQDYQQAQQTQRDA----KQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEK---LRQRLEQAEQERT 1002

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1380 QLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMER-------------DALRIR------AIEAEDLKRKEMEET 1440
Cdd:PRK04863  1003 RAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQElqdlgvpadsgaeERARARrdelhaRLSANRSRRNQLEKQ 1082

                          330       340
                   ....*....|....*....|....*
gi 1338812033 1441 IVKLKSEILTHTTKLEHLNKWHQQQ 1465
Cdd:PRK04863  1083 LTFCEAEMDNLTKKLRKLERDYHEM 1107
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 473-705 3.98e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 3.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  473 EREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQelheRV 552
Cdd:COG3883     27 ELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGG----SV 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  553 DHLGSVLNSKeeearsNAEEWarerheISRqqevlMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQsv 632
Cdd:COG3883    103 SYLDVLLGSE------SFSDF------LDR-----LSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK-- 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338812033  633 ewsllSELRKEKQELEQKVSSIEAIVDNLrtrchgleldsEAQRASHQEEVESLKRKLHEAESILGVYEGKLA 705
Cdd:COG3883    164 -----AELEAAKAELEAQQAEQEALLAQL-----------SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1150-1349 5.57e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.84  E-value: 5.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1150 QLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASAlasekdsqlellhaelkERDSLRIQAAEMEARHKE 1229
Cdd:COG1579      8 ALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKT-----------------ELEDLEKEIKRLELEIEE 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1230 LEESIAQLQAQLGTASvlasekdsqleslhaELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDL 1309
Cdd:COG1579     71 VEARIKKYEEQLGNVR---------------NNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAE 135

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1338812033 1310 LHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASER 1349
Cdd:COG1579    136 LEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 294-956 5.80e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 5.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  294 ELKTNKTQMERKIDDLTEENGILSVQMR-----EIFSRLSSAEAAVQKLSAEQESSQVEWESK---RGLLESELGQALSQ 365
Cdd:pfam12128  215 KSRLNRQQVEHWIRDIQAIAGIMKIRPEftklqQEFNTLESAELRLSHLHFGYKSDETLIASRqeeRQETSAELNQLLRT 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  366 KE-YLNEQIQILQGKISILEDELSKAKAEtLGGGEVMGPIMEWERLNQEIADLNH------KLSQLQEIIIQLQKEKKEI 438
Cdd:pfam12128  295 LDdQWKEKRDELNGELSAADAAVAKDRSE-LEALEDQHGAFLDADIETAAADQEQlpswqsELENLEERLKALTGKHQDV 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  439 EMMYEVEK--------TKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQrvsleaqieaLTADIASLTEAVQQRE 510
Cdd:pfam12128  374 TAKYNRRRskikeqnnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQ----------LEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  511 LAVTNFSQKVDverkRVEKLTEEMEKQERFaqktiqelHERVDHlgsvLNSKEEEARSNAEEWARERheisrqqEVLMEA 590
Cdd:pfam12128  444 SRLGELKLRLN----QATATPELLLQLENF--------DERIER----AREEQEAANAEVERLQSEL-------RQARKR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  591 RETISRERDAIATEYQHFQQEKEEVACKLNQQivlleeqqsvEWSLLSELRKEKQELEQKVSSIEAIVDNLRTrchglEL 670
Cdd:pfam12128  501 RDQASEALRQASRRLEERQSALDELELQLFPQ----------AGTLLHFLRKEAPDWEQSIGKVISPELLHRT-----DL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  671 DSEAQRASHQEEVESLKRKLHEAESILGVYegkLADHQKIVEEHIALRDELSAAAECAKGLRDEL-----EVERSKHKET 745
Cdd:pfam12128  566 DPEVWDGSVGGELNLYGVKLDLKRIDVPEW---AASEEELRERLDKAEEALQSAREKQAAAEEQLvqangELEKASREET 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  746 LAAKLQSKSQMMEemreleektQNMSVEMQHLGQQLSK-VQQEKMRVDASMAKLIEEGREVERGLTAARDQAFLTIKE-R 823
Cdd:pfam12128  643 FARTALKNARLDL---------RRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREaR 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  824 EAETSKLRSEAEALSSKVILAEEAKAIELAKKDDEMQVLSKEMKQIQMELG----TVKKAKDDMElDLQSSIEK----RQ 895
Cdd:pfam12128  714 TEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGvdpdVIAKLKREIR-TLERKIERiavrRQ 792

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033  896 EQLLVLRFQMNELEESANQKETEIEVLQTKLSNKDEELKAFCLHEKVEREELQRQLKQEED 956
Cdd:pfam12128  793 EVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEK 853
PRK09039 PRK09039
peptidoglycan -binding protein;
406-510 6.21e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 47.65  E-value: 6.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  406 EWERLNQEIADLNHKLS-------QLQEIIIQLQKEKKEIEmmyevektkfeAEKARLEELVSELNKMLTVQRGEREALE 478
Cdd:PRK09039    54 ALDRLNSQIAELADLLSlerqgnqDLQDSVANLRASLSAAE-----------AERSRLQALLAELAGAGAAAEGRAGELA 122

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1338812033  479 QALREQR-VSLEA---------QIEALTADIASLTEAVQQRE 510
Cdd:PRK09039   123 QELDSEKqVSARAlaqvellnqQIAALRRQLAALEAALDASE 164
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
272-507 6.68e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  272 EQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSV--QMREIFSRLSSAEAAVQKLSAEQESSQVEWE 349
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLseEAKLLLQQLSELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  350 SKRGLLESELGQALSQKEylNEQIQILQGKISILEDELSKAKAeTLGGGEvmgPIMewERLNQEIADLNHKLSQLQEIII 429
Cdd:COG3206    244 ALRAQLGSGPDALPELLQ--SPVIQQLRAQLAELEAELAELSA-RYTPNH---PDV--IALRAQIAALRAQLQQEAQRIL 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  430 QlqkekkEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRG----EREAleQALREQRVSLEAQIEALTADIASLTEA 505
Cdd:COG3206    316 A------SLEAELEALQAREASLQAQLAQLEARLAELPELEAElrrlEREV--EVARELYESLLQRLEEARLAEALTVGN 387


                   ..
gi 1338812033  506 VQ 507
Cdd:COG3206    388 VR 389
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
453-957 7.47e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 7.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  453 KARLEELVSELNKMLTVQRGEREALEQALREQRvSLEAQIEALTADIASLTEAVQQRELAVTNFSQkvDVERKRVEKLTE 532
Cdd:COG4717     52 EKEADELFKPQGRKPELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELRE--ELEKLEKLLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  533 EMEKQERFAQKTIQELHERVDHLgsvlnskeeeaRSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQEK 612
Cdd:COG4717    129 PLYQELEALEAELAELPERLEEL-----------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  613 EEVACKLNQQIVLLEEQqsvewslLSELRKEKQELEQKVSSIEAivdnlrtrchgleldseaqrashQEEVESLKRKLHE 692
Cdd:COG4717    198 AEELEELQQRLAELEEE-------LEEAQEELEELEEELEQLEN-----------------------ELEAAALEERLKE 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  693 AESILGVyEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMreleektqnmSV 772
Cdd:COG4717    248 ARLLLLI-AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE----------EL 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  773 EMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARDQafltikEREAETSKLRSEAEALSSKVILAEEAKAIEL 852
Cdd:COG4717    317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL------EEELQLEELEQEIAALLAEAGVEDEEELRAA 390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  853 AKKDDEMQVLSKEMKQIQMEL-----GTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQTklS 927
Cdd:COG4717    391 LEQAEEYQELKEELEELEEQLeellgELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE--D 468

                          490       500       510
                   ....*....|....*....|....*....|
gi 1338812033  928 NKDEELKAfclhekvEREELQRQLKQEEDR 957
Cdd:COG4717    469 GELAELLQ-------ELEELKAELRELAEE 491
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1048-1414 8.98e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 8.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1048 QLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSE 1127
Cdd:pfam07888   35 RLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELS 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1128 ERIAQLQARLGTASALASEKDSQLELLHAELKERDslriqaAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLH 1207
Cdd:pfam07888  115 EEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE------TELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELR 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1208 AELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTasvlASEKDSQLESLHAELKE-RDGLRIQAAEMEARHKELEESI 1286
Cdd:pfam07888  189 SLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTT----AHRKEAENEALLEELRSlQERLNASERKVEGLGEELSSMA 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1287 AQL--------QARLgtASALASGKQSELDLLHKEVR-----EREKLRiRAVEVEEAQHKELEERVTEASTLASERKSQL 1353
Cdd:pfam07888  265 AQRdrtqaelhQARL--QAAQLTLQLADASLALREGRarwaqERETLQ-QSAEADKDRIEKLSAELQRLEERLQEERMER 341

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1354 DSLHNEMNEKDHVIKTQHMELESTVTQLKeqlhtaTSLAAVQKRVNEKLNEDIRRLDVVRQ 1414
Cdd:pfam07888  342 EKLEVELGREKDCNRVQLSESRRELQELK------ASLRVAQKEKEQLQAEKQELLEYIRQ 396
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1219-1421 9.51e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1219 QAAEMEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELKER----DGLRIQAAEMEARHKELEESIAQLQARLG 1294
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALarriRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1295 T---------ASALASGKQSELDLL------HKEVREREKLR--IRAVEVEEAQHKELEERVTEASTLASERKSQLDSLH 1357
Cdd:COG4942    101 AqkeelaellRALYRLGRQPPLALLlspedfLDAVRRLQYLKylAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1338812033 1358 NEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDA 1421
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
PTZ00121 PTZ00121
MAEBL; Provisional
 213-951 1.18e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  213 RKLQKQLVQEREMRDELERELASRSQVITE-REMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEGLLTRLHDVLKQ 291
Cdd:PTZ00121  1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKK 1303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  292 CQELKtNKTQMERKIDDLTEengilsvQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLNE 371
Cdd:PTZ00121  1304 ADEAK-KKAEEAKKADEAKK-------KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  372 QIQilqgkisilEDELSKAKAETLGGGEvmgpimEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEA 451
Cdd:PTZ00121  1376 AKK---------KADAAKKKAEEKKKAD------EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  452 EKARLEElvsELNKMLTVQRGEREALEQAlREQRVSLEAQIEAltadiaslTEAVQQRELavtnfSQKVDVERKRVEKLT 531
Cdd:PTZ00121  1441 EEAKKAD---EAKKKAEEAKKAEEAKKKA-EEAKKADEAKKKA--------EEAKKADEA-----KKKAEEAKKKADEAK 1503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  532 EEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEwaRERHEISRQQEVLMEARETISRERDAIATEYQHFQQE 611
Cdd:PTZ00121  1504 KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE--KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR 1581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  612 KEEVACKLnqqivlleEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQRASHQEEVESLKRKLH 691
Cdd:PTZ00121  1582 KAEEAKKA--------EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  692 EAESILGVyegKLADHQKIVEEHIALRDELSAAAECAKGLRDEL--EVERSKHKETLAAKLQSKSQMMEEMRELEEKTQN 769
Cdd:PTZ00121  1654 KAEEENKI---KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  770 MSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREVERGLTAARDQAFLTIKEREAETSKLRSEAEALSSKVILAEEAKA 849
Cdd:PTZ00121  1731 KAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANI 1810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  850 IELAKKDDEMQVLSKEmkqiqMELGTVKKAKDDMELDLQSSIEKRQEqllvlRFQMNELEESANQKETEIEVLQTKLSNK 929
Cdd:PTZ00121  1811 IEGGKEGNLVINDSKE-----MEDSAIKEVADSKNMQLEEADAFEKH-----KFNKNNENGEDGNKEADFNKEKDLKEDD 1880

                          730       740
                   ....*....|....*....|..
gi 1338812033  930 DEELKAFCLHEKVEREELQRQL 951
Cdd:PTZ00121  1881 EEEIEEADEIEKIDKDDIEREI 1902
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1086-1659 1.20e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1086 NEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELK----ER 1161
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSkinsEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1162 DSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEESIAQLQAQL 1241
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYND---LKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1242 GTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSEL-DLLHKEVREREKL 1320
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLnQLKDEQNKIKKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1321 RIRAVEVEEAQHK--ELEERV----TEASTLASERKSQLDS-LHNEMNEKDH---VIKTQHMELESTVTQLKEQLhtats 1390
Cdd:TIGR04523  270 SEKQKELEQNNKKikELEKQLnqlkSEISDLNNQKEQDWNKeLKSELKNQEKkleEIQNQISQNNKIISQLNEQI----- 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1391 lAAVQKRVNEKLNEDirrldVVRQESMERDALRIRAIEAEDLKRKEmeeTIVKLKSEILTHTTKLEHLNKWHQQqlsvLR 1470
Cdd:TIGR04523  345 -SQLKKELTNSESEN-----SEKQRELEEKQNEIEKLKKENQSYKQ---EIKNLESQINDLESKIQNQEKLNQQ----KD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1471 NENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLlplqECKAEN-ERLIGDLQEQLQAKTEAMKHCKAQVQMA 1549
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK----ELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1550 KTHYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQ---------AKLSEKDLALKVNSLQAQVDYAD 1620
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEkeskisdleDELNKDDFELKKENLEKEIDEKN 567

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1338812033 1621 RQLREYaKHGIDTTLNtckppSQEERSEKLADLSKDSLD 1659
Cdd:TIGR04523  568 KEIEEL-KQTQKSLKK-----KQEEKQELIDQKEKEKKD 600
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1250-1613 1.24e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.38  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1250 EKDSQLESLHAELKERDGLRiqaaemEARHKELEESIAQLQARLGTASALasgKQSELDLLHKEVREREKLRiraVEVEE 1329
Cdd:COG5022    814 SYLACIIKLQKTIKREKKLR------ETEEVEFSLKAEVLIQKFGRSLKA---KKRFSLLKKETIYLQSAQR---VELAE 881

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1330 AQHKELEERVTEASTLaSERKSQLDSLHNEMN---EKDHVIKTQHM-ELESTVTQLKE--QLHTATSLAAVQKRVNEKLN 1403
Cdd:COG5022    882 RQLQELKIDVKSISSL-KLVNLELESEIIELKkslSSDLIENLEFKtELIARLKKLLNniDLEEGPSIEYVKLPELNKLH 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1404 EDIRRLdvvRQESMERDALRiraieaedlkrKEMEETIVKLKseilthtTKLEHLNKWhQQQLSVLRnENQTLLSMKESM 1483
Cdd:COG5022    961 EVESKL---KETSEEYEDLL-----------KKSTILVREGN-------KANSELKNF-KKELAELS-KQYGALQESTKQ 1017

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1484 VKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKaeneRLIGDLQEQLQAKTEAMKhckaqvQMAKTHYNGKKQqlLEV 1563
Cdd:COG5022   1018 LKELPVEVAELQSASKIISSESTELSILKPLQKLK----GLLLLENNQLQARYKALK------LRRENSLLDDKQ--LYQ 1085

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033 1564 QEKAQTLENTLESRDQEVK---VLRSEMKLL-----QIELDQAKLSEKDLALKVNSLQ 1613
Cdd:COG5022   1086 LESTENLLKTINVKDLEVTnrnLVKPANVLQfivaqMIKLNLLQEISKFLSQLVNTLE 1143
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 566-812 1.29e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  566 ARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQEKEEvackLNQQIVLLEEQQSVEWSLLSELRKEKQ 645
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA----LARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  646 ELEQKvssIEAIVDNLRtrchglELDSEAQRASHQEEVESLKRklheAESILGVYEgKLADHQKIVEEHIALRDELSAAA 725
Cdd:COG4942     94 ELRAE---LEAQKEELA------ELLRALYRLGRQPPLALLLS----PEDFLDAVR-RLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  726 ECAKGLRDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGREV 805
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                   ....*..
gi 1338812033  806 ERGLTAA 812
Cdd:COG4942    240 AERTPAA 246
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1273-1627 1.32e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1273 AEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQ 1352
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1353 LDSLHNEMNEKDHVIKTQHMELESTVTQLKEqlhtatslaaVQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDL 1432
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEE----------LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1433 KRKEMEETIVKLKSEILTHTTKLEHLNKwHQQQLSVLRNENQTLLS--MKESMVKEQEVSQRVKVSLESKLKLAgQELSV 1510
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELER-EIEEERKRRDKLTEEYAelKEELEDLRAELEEVDKEFAETRDELK-DYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1511 LLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKL 1590
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1338812033 1591 LQIELDQAKLSEKDLALKVNSLQAQVDYADRQLREYA 1627
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGR 510
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
358-736 1.35e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  358 ELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETlgggevmgpimewERLNQEIADLNHKLsQLQEIIIQLQKEKKE 437
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL-------------EELREELEKLEKLL-QLLPLYQELEALEAE 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  438 IEMmYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFS 517
Cdd:COG4717    141 LAE-LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  518 QKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWA-----------RERHEISRQQEV 586
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlflvlgllaLLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  587 LMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEE--QQSVEW-SLLSELRKEKQELEQKvsSIEAIVDNLRT 663
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEllDRIEELqELLREAEELEEELQLE--ELEQEIAALLA 377

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1338812033  664 RCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHiALRDELSAAAECAKGLRDELE 736
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELE 449
PRK11281 PRK11281
mechanosensitive channel MscK;
201-423 1.36e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  201 IQDVLNTPQFRLRKLQKQlvqeREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEqqpkEIEQLQRKNEG 280
Cdd:PRK11281    61 VQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTL----SLRQLESRLAQ 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  281 LLTRLHDVLKQCQE----LKTNKTQMERKIDDLTEEngilSVQMREIFSRLSSAEAA--------VQKLSAEQESSQVEW 348
Cdd:PRK11281   133 TLDQLQNAQNDLAEynsqLVSLQTQPERAQAALYAN----SQRLQQIRNLLKGGKVGgkalrpsqRVLLQAEQALLNAQN 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  349 ESKRGLLES-----ELGQalSQKEYLNEQIQILQGKISILED-------ELSKAKAETLGGGEVMGPIMEWERLNQEIaD 416
Cdd:PRK11281   209 DLQRKSLEGntqlqDLLQ--KQRDYLTARIQRLEHQLQLLQEainskrlTLSEKTVQEAQSQDEAARIQANPLVAQEL-E 285


                   ....*..
gi 1338812033  417 LNHKLSQ 423
Cdd:PRK11281   286 INLQLSQ 292
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 218-622 1.42e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 47.04  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  218 QLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKNEglltrlhdvlKQCQELKT 297
Cdd:pfam05557   98 QLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE----------KQQSSLAE 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  298 NktqmERKIDDLTEENGiLSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESelgqalsqKEYLNEQIQILQ 377
Cdd:pfam05557  168 A----EQRIKELEFEIQ-SQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIEN--------KLLLKEEVEDLK 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  378 GKISILEDELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEkkeiEMMYEVEKTKFEAEKARLE 457
Cdd:pfam05557  235 RKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQR----EIVLKEENSSLTSSARQLE 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  458 ELVSELNKMLTVQRGEREALEQALREQ---RVSLEAQIEALTADIASLTEAVQQ--RELAVTNFSQKVDVERKRVEKLTE 532
Cdd:pfam05557  311 KARRELEQELAQYLKKIEDLNKKLKRHkalVRRLQRRVLLLTKERDGYRAILESydKELTMSNYSPQLLERIEEAEDMTQ 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  533 EMekqerfaQKTIQELHERVDHLGSVLNSKEEEARSNAEEW-ARERHEISRQQEVLMEARETISRERDAIATEYQHFQQE 611
Cdd:pfam05557  391 KM-------QAHNEEMEAQLSVAEEELGGYKQQAQTLERELqALRQQESLADPSYSKEEVDSLRRKLETLELERQRLREQ 463

                          410
                   ....*....|.
gi 1338812033  612 KEEVACKLNQQ 622
Cdd:pfam05557  464 KNELEMELERR 474
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1202-1385 1.56e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1202 QLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLgtasvlasekdsqlESLHAELKErdgLRIQAAEMEARHKE 1281
Cdd:COG1579      8 ALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARL--------------EAAKTELED---LEKEIKRLELEIEE 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1282 LEESIAQLQARLGTASAL--ASGKQSELDLLHKEVREREKLRIRAVEveeaQHKELEERVTEASTLASERKSQLDSLHNE 1359
Cdd:COG1579     71 VEARIKKYEEQLGNVRNNkeYEALQKEIESLKRRISDLEDEILELME----RIEELEEELAELEAELAELEAELEEKKAE 146

                          170       180
                   ....*....|....*....|....*.
gi 1338812033 1360 MNEKDHVIKTQHMELESTVTQLKEQL 1385
Cdd:COG1579    147 LDEELAELEAELEELEAEREELAAKI 172
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1250-1628 1.78e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1250 EKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVReREKLRIRAVEVEE 1329
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPER-LEELEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1330 AQHkELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRL 1409
Cdd:COG4717    161 LEE-ELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1410 DVVRQESMERDALRIRAI-------------------------------------EAEDLKRKEMEETIVKLKSEILTHT 1452
Cdd:COG4717    240 ALEERLKEARLLLLIAAAllallglggsllsliltiagvlflvlgllallflllaREKASLGKEAEELQALPALEELEEE 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1453 TKLEHLnkwhqQQLSVLRNENQTLLSMKESMVKEQEVSQRVKVSLESKLKLAGQELSVLLPLQECKAENE---RLIGDLQ 1529
Cdd:COG4717    320 ELEELL-----AALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEeelRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1530 EQLQAKTEAMKHCKAQVQMAKT--HYNGKKQQLLEVQEKAQTLENTLESRDQEVKVLRSEMKLLQIELDQAKLSEkdlal 1607
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGelEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDG----- 469

                          410       420
                   ....*....|....*....|.
gi 1338812033 1608 KVNSLQAQVDYADRQLREYAK 1628
Cdd:COG4717    470 ELAELLQELEELKAELRELAE 490
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 964-1202 2.07e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  964 EIVVKDKEVNFLKMAMVAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQA---ISTLEIRLSDAHRLLEEKASSIE 1040
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLqaeIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1041 MQTSQVMQLQRDLSTEQ-----ERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQ 1115
Cdd:COG3883     97 RSGGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1116 VAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASAL 1195
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAG 256


                   ....*..
gi 1338812033 1196 ASEKDSQ 1202
Cdd:COG3883    257 AAAGSAG 263
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 911-1184 2.14e-04

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 45.57  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  911 SANQKETEIEVLQTKLSNKDEELKAFCLHEK------VEREELQRQLKQ--EEDRCLMYKQEIVVKDKEVNFLKMAMVAK 982
Cdd:pfam15905   50 PATARKVKSLELKKKSQKNLKESKDQKELEKeiralvQERGEQDKRLQAleEELEKVEAKLNAAVREKTSLSASVASLEK 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  983 EeeinsLMQSIHSGE-EKASAFQDLQEKRheeqkqaISTLEIRLSDAHRLLEEKASSI----EMQTSQVMQLQRDLSTEQ 1057
Cdd:pfam15905  130 Q-----LLELTRVNElLKAKFSEDGTQKK-------MSSLSMELMKLRNKLEAKMKEVmakqEGMEGKLQVTQKNLEHSK 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1058 ERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARL 1137
Cdd:pfam15905  198 GKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQI 277

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1338812033 1138 GTASALASEKDSQLELLHAELKERDSLRIqaAEMEarhkELEESIAQ 1184
Cdd:pfam15905  278 KDLNEKCKLLESEKEELLREYEEKEQTLN--AELE----ELKEKLTL 318
PRK01156 PRK01156
chromosome segregation protein; Provisional
 229-663 2.21e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  229 LERELASRSQVITEREMQVSqlqhRVQRMMRDSEEQEQQPKEIEQLQRKNEGL---LTRLHDVLKQCQELKTNKTQMERK 305
Cdd:PRK01156   303 YKNDIENKKQILSNIDAEIN----KYHAIIKKLSVLQKDYNDYIKKKSRYDDLnnqILELEGYEMDYNSYLKSIESLKKK 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  306 IDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLNEQIQIL--QGKISIL 383
Cdd:PRK01156   379 IEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngQSVCPVC 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  384 EDELSKAKAETLgggeVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQK-----EKKEIEmMYEVEKTKFEAEKARLEE 458
Cdd:PRK01156   459 GTTLGEEKSNHI----INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKrkeylESEEIN-KSINEYNKIESARADLED 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  459 LVSELNKMltvqrGEREALEQALREQRVSLEaqIEALTADIASLTEAVQQRELAvtnfsqKVDVERKRVEKLTEEMEKQE 538
Cdd:PRK01156   534 IKIKINEL-----KDKHDKYEEIKNRYKSLK--LEDLDSKRTSWLNALAVISLI------DIETNRSRSNEIKKQLNDLE 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  539 RFAQKTIQELHERVDHLGSVLNSKEEEARsNAEEWARERHEISRQQEVLmeaRETISRERDAIAtEYQHFQQEKEEVACK 618
Cdd:PRK01156   601 SRLQEIEIGFPDDKSYIDKSIREIENEAN-NLNNKYNEIQENKILIEKL---RGKIDNYKKQIA-EIDSIIPDLKEITSR 675

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033  619 LNQ----------QIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRT 663
Cdd:PRK01156   676 INDiednlkksrkALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 847-1102 2.22e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  847 AKAIELAKKDDEMQVLSKEMKQIQMELGTVKKAKDDMELDLQS---SIEKRQEQLLVLRFQMNELEESANQKETEIEVLQ 923
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAlerRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  924 TKLSNKDEELKAFCLhekvereELQRQLKQEEDRCLMYKQEIVVKDKEVNFLKMAMVAKEEEINSLMQSIhsgeekasaf 1003
Cdd:COG4942     97 AELEAQKEELAELLR-------ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL---------- 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1004 QDLQEKRhEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIhcKLEKEA 1083
Cdd:COG4942    160 AELAALR-AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA--RLEAEA 236

                          250
                   ....*....|....*....
gi 1338812033 1084 LKNEVTSLQELAEKLKGEL 1102
Cdd:COG4942    237 AAAAERTPAAGFAALKGKL 255
PRK01156 PRK01156
chromosome segregation protein; Provisional
 488-1035 2.32e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  488 LEAQIEALTADIASLTEAVQQRELAVTNFSQKVDvERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEAR 567
Cdd:PRK01156   216 TLKEIERLSIEYNNAMDDYNNLKSALNELSSLED-MKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNR 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  568 SNAEEWARERHEISRQQEVLMEARETISRERDAI--ATEYQHFQQEKEEVACK---LNQQIVLLEEQQSVEWSLLSELRK 642
Cdd:PRK01156   295 NYINDYFKYKNDIENKKQILSNIDAEINKYHAIIkkLSVLQKDYNDYIKKKSRyddLNNQILELEGYEMDYNSYLKSIES 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  643 EKQELEQKVSSIEAIVDNLRTRCHGLELDSEAQRAshqeEVESLKRKLHEAESILG---VYEGKLADHQKIVEEHIALRD 719
Cdd:PRK01156   375 LKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKK----ELNEINVKLQDISSKVSslnQRIRALRENLDELSRNMEMLN 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  720 ELSAAAECAKGLRDELEVERSKHKETLAAKLQSksqmmeemreleektqnmsvEMQHLGQQLSKVQQEKMRVDASMAKLi 799
Cdd:PRK01156   451 GQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEE--------------------KIREIEIEVKDIDEKIVDLKKRKEYL- 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  800 eEGREVERGLTAARdqaflTIKEREAETSKLrseaealsskvilaeEAKAIELAKKDDEMQVLSKEMKQIQMELGTVKKA 879
Cdd:PRK01156   510 -ESEEINKSINEYN-----KIESARADLEDI---------------KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRT 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  880 KDDMELDLQSSI--EKRQEQLLVLRFQMNELEESANQKETEIEVLQTKLSNK----DEELKAFcLHEKVEREELQRQLKQ 953
Cdd:PRK01156   569 SWLNALAVISLIdiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSireiENEANNL-NNKYNEIQENKILIEK 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  954 EEDRCLMYKQEIVVKDKEVNFLKmAMVAKEEEINSLMQSIHSGEEKASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLE 1033
Cdd:PRK01156   648 LRGKIDNYKKQIAEIDSIIPDLK-EITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE 726


                   ..
gi 1338812033 1034 EK 1035
Cdd:PRK01156   727 SM 728
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1136-1635 2.65e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 2.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1136 RLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARlgtasalasekdSQLELLHAElKERDS 1215
Cdd:TIGR00618  150 PQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLR------------SQLLTLCTP-CMPDT 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1216 LRIQAAEMEARHKELEESIAQLQ---AQLGTASVLASEKDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQAR 1292
Cdd:TIGR00618  217 YHERKQVLEKELKHLREALQQTQqshAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLA 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1293 LGTASALASGKQSELDLLHKEVREREKLRIRA-VEVEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHviKTQH 1371
Cdd:TIGR00618  297 AHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMkRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREI--SCQQ 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1372 MELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVvrqESMERDALRIRAIEAEdlKRKEMEETIVKLKSEILTH 1451
Cdd:TIGR00618  375 HTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDT---RTSAFRDLQGQLAHAK--KQQELQQRYAELCAAAITC 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1452 TTKLEHLNKWHQQQLSVLRNENQTLLSMKESMV-----KEQEVSQRVKVSLESKLKLAGQEL----------------SV 1510
Cdd:TIGR00618  450 TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHlqetrKKAVVLARLLELQEEPCPLCGSCIhpnparqdidnpgpltRR 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1511 LLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLES-RDQEVKVLRSEMK 1589
Cdd:TIGR00618  530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRlQDLTEKLSEAEDM 609

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1338812033 1590 LLQIELDQAKLSEKDLALKVNSLQAQVDYADRQLREYAKHGIDTTL 1635
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTL 655
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1108-1351 2.80e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1108 EHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKE-RDSLRIQAAEMEARHKELEESIAQLQ 1186
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKlQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1187 ARLGTASALAS--EKDSQLELLHaelkerdslRIQAAE-MEARHKELEESIAQLQAQLGTASVLASEKDSQLESLHAELK 1263
Cdd:COG3883     97 RSGGSVSYLDVllGSESFSDFLD---------RLSALSkIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1264 ErdglriQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEAS 1343
Cdd:COG3883    168 A------AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 241


                   ....*...
gi 1338812033 1344 TLASERKS 1351
Cdd:COG3883    242 AAASAAGA 249
CH_SF cd00014
calponin homology (CH) domain superfamily; CH domains are actin filament (F-actin) binding ...
 8-70 2.99e-04

calponin homology (CH) domain superfamily; CH domains are actin filament (F-actin) binding motifs, which may be present as a single copy or in tandem repeats (which increase binding affinity). They either function as autonomous actin binding motifs or serve a regulatory function. CH domains are found in cytoskeletal and signal transduction proteins, including actin-binding proteins like spectrin, alpha-actinin, dystrophin, utrophin, and fimbrin, as well as proteins essential for regulation of cell shape (cortexillins), and signaling proteins (Vav).


Pssm-ID: 409031 [Multi-domain]  Cd Length: 103  Bit Score: 41.94  E-value: 2.99e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033    8 EEALLNWINSL---HLDSPIDHIF-LLQDGVILVKLIHKLKKQEIGVDAVLELPLQGRLDFISAFLQ 70
Cdd:cd00014      1 EEELLKWINEVlgeELPVSITDLFeSLRDGVLLCKLINKLSPGSIPKINKKPKSPFKKRENINLFLN 67
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 408-662 3.45e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 45.62  E-value: 3.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  408 ERLNQEIADLNHKLSQLQEIIIQLQKE------------KKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTvqRGERE 475
Cdd:pfam06160  182 EKLEEETDALEELMEDIPPLYEELKTElpdqleelkegyREMEEEGYALEHLNVDKEIQQLEEQLEENLALLE--NLELD 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  476 ALEQALREqrvsLEAQIEALTADIaslteavqQRELAVtnfsqkvdveRKRVEKLTEEMEKQERFAQKTIQELHERVDHL 555
Cdd:pfam06160  260 EAEEALEE----IEERIDQLYDLL--------EKEVDA----------KKYVEKNLPEIEDYLEHAEEQNKELKEELERV 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  556 GS--VLNSKEEEarsNAEEWARERHEISRQQEVLMEAREtisrERDAIATEYQHFQQEkeevackLNQQIVLLEEQQSVE 633
Cdd:pfam06160  318 QQsyTLNENELE---RVRGLEKQLEELEKRYDEIVERLE----EKEVAYSELQEELEE-------ILEQLEEIEEEQEEF 383

                          250       260
                   ....*....|....*....|....*....
gi 1338812033  634 WSLLSELRKEKQELEQKVSSIEAIVDNLR 662
Cdd:pfam06160  384 KESLQSLRKDELEAREKLDEFKLELREIK 412
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 455-604 3.50e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  455 RLEELVSELNKmLTVQRGEREALEQALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKR-------- 526
Cdd:COG1579     11 DLQELDSELDR-LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrnnk 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  527 -VEKLTEEMEKQER---FAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIA 602
Cdd:COG1579     90 eYEALQKEIESLKRrisDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169


                   ..
gi 1338812033  603 TE 604
Cdd:COG1579    170 AK 171
46 PHA02562
endonuclease subunit; Provisional
 857-1108 3.56e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  857 DEMQVLSKEMKQIQMELGTVKKaKDDMELDLQSSIEKRQEQLLV-LRFQMNELEESANQKETEIEVLQTKLSNKDEELKa 935
Cdd:PHA02562   174 DKIRELNQQIQTLDMKIDHIQQ-QIKTYNKNIEEQRKKNGENIArKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIE- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  936 fclhekvEREELQRQLKQEEDRCLMYKQEIvvkDKEVNFLKmamvaKEEEINSLMQSIHSGEEKASafqDLQEKRHEEQK 1015
Cdd:PHA02562   252 -------DPSAALNKLNTAAAKIKSKIEQF---QKVIKMYE-----KGGVCPTCTQQISEGPDRIT---KIKDKLKELQH 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1016 QaistLEiRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELA 1095
Cdd:PHA02562   314 S----LE-KLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDEL 388

                          250
                   ....*....|...
gi 1338812033 1096 EKLKGELEELKRE 1108
Cdd:PHA02562   389 DKIVKTKSELVKE 401
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
408-585 5.67e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  408 ERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEmmyevektKFEAEKARLEELVSELNKMLTVQRG------EREALE--- 478
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQ--------ERREALQRLAEYSWDEIDVASAEREiaeleaELERLDass 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  479 ---QALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERF-AQKTIQELHERvDH 554
Cdd:COG4913    685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAlLEERFAAALGD-AV 763

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1338812033  555 LGSVLNSKEEEARSNAEEWARERHEISRQQE 585
Cdd:COG4913    764 ERELRENLEERIDALRARLNRAEEELERAMR 794
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
439-689 6.72e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 6.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  439 EMMYEVEKTKFEAEKARleELVSELNKMltvqrgeREALEQAlREQRVSLEaQIEALTADIASLTEAVQQRELAVTNF-- 516
Cdd:COG4913    215 EYMLEEPDTFEAADALV--EHFDDLERA-------HEALEDA-REQIELLE-PIRELAERYAAARERLAELEYLRAALrl 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  517 ---SQKVDVERKRVEKLTEEMEK---QERFAQKTIQELHERVDHLgsvlnskeEEARSNAEewARERHEISRQQEVLMEA 590
Cdd:COG4913    284 wfaQRRLELLEAELEELRAELARleaELERLEARLDALREELDEL--------EAQIRGNG--GDRLEQLEREIERLERE 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  591 RETISRERDaiateyqhfqqekeevacKLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRCHGLEL 670
Cdd:COG4913    354 LEERERRRA------------------RLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR 415

                          250
                   ....*....|....*....
gi 1338812033  671 DSEAQRASHQEEVESLKRK 689
Cdd:COG4913    416 DLRRELRELEAEIASLERR 434
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 263-519 7.14e-04

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 44.03  E-value: 7.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  263 EQEQQPKEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMRE--IFSRLSSAEAAVQKLSAE 340
Cdd:pfam15905   88 ERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELTRVNELLKAKFSEdgTQKKMSSLSMELMKLRNK 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  341 QESSQVEWESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLgggevmgpimEWERLNQEIADLNHK 420
Cdd:pfam15905  168 LEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETE----------KLLEYITELSCVSEQ 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  421 LSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSLEAQIEaltadia 500
Cdd:pfam15905  238 VEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLNAELE------- 310

                          250
                   ....*....|....*....
gi 1338812033  501 SLTEAVQQRELAVTNFSQK 519
Cdd:pfam15905  311 ELKEKLTLEEQEHQKLQQK 329
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1101-1627 7.40e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 7.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1101 ELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTASALASEKDSQLELLHAELKErdsLRIQAAEMEARHKELEE 1180
Cdd:pfam01576   13 ELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQE---LEEILHELESRLEEEEE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1181 SIAQLQARLGTASALASEKDSQLEllhAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGTASvlasekdsqleslha 1260
Cdd:pfam01576   90 RSQQLQNEKKKMQQHIQDLEEQLD---EEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLS--------------- 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1261 elKERDGLRIQAAEMEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKLRIRAveveEAQHKELEERVT 1340
Cdd:pfam01576  152 --KERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKL----EGESTDLQEQIA 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1341 EASTLASERKSQL-----------DSLHNEMNEKDHVIKtQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRL 1409
Cdd:pfam01576  226 ELQAQIAELRAQLakkeeelqaalARLEEETAQKNNALK-KIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEAL 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1410 dvvrqESMERDALRIRAIEAEDLKRKEMEETIVK--LKSEILTHTTKLEHLNKWHQQQLsvlrnenqtllsmkESMVKEQ 1487
Cdd:pfam01576  305 -----KTELEDTLDTTAAQQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQAL--------------EELTEQL 365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1488 EVSQRVKVSLEsKLKlagqelsvllplQECKAENERLIGDLQEQLQAKTEA---MKHCKAQVQMAKTHYNGKKQQLLEVQ 1564
Cdd:pfam01576  366 EQAKRNKANLE-KAK------------QALESENAELQAELRTLQQAKQDSehkRKKLEGQLQELQARLSESERQRAELA 432

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1565 EKAQTLEN------------------------TLESRDQEVKVLRSE---------MKLLQIELDQAKLSE--------- 1602
Cdd:pfam01576  433 EKLSKLQSelesvssllneaegkniklskdvsSLESQLQDTQELLQEetrqklnlsTRLRQLEDERNSLQEqleeeeeak 512

                          570       580
                   ....*....|....*....|....*
gi 1338812033 1603 KDLALKVNSLQAQVDYADRQLREYA 1627
Cdd:pfam01576  513 RNVERQLSTLQAQLSDMKKKLEEDA 537
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 211-381 7.56e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 7.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQrkneglltrlhdvlk 290
Cdd:COG1579     18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL--------------- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  291 qcQELKTNK--TQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEY 368
Cdd:COG1579     83 --GNVRNNKeyEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160

                          170
                   ....*....|...
gi 1338812033  369 LNEQIQILQGKIS 381
Cdd:COG1579    161 LEAEREELAAKIP 173
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
209-604 8.15e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  209 QFRLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRmmRDSEEQEQQPKEIEQLQRKNEGLLTRLHDV 288
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLERELEERERRRARL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  289 LKQC-----------QELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQ-------VEWES 350
Cdd:COG4913    365 EALLaalglplpasaEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLErrksnipARLLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  351 KRGLLESELGQALSQKEYLNEQIQIL------QGKI---------SIL-----EDELSKA-------------KAETLGG 397
Cdd:COG4913    445 LRDALAEALGLDEAELPFVGELIEVRpeeerwRGAIervlggfalTLLvppehYAAALRWvnrlhlrgrlvyeRVRTGLP 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  398 GEVM----------------GPIMEWerLNQEIA------------DLNH------------------------------ 419
Cdd:COG4913    525 DPERprldpdslagkldfkpHPFRAW--LEAELGrrfdyvcvdspeELRRhpraitragqvkgngtrhekddrrrirsry 602

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  420 --------KLSQLQEIIIQLQKEKKEIEMmyevEKTKFEAEKARLEELVSELNKMLTVQRGEREAleQALREQRVSLEAQ 491
Cdd:COG4913    603 vlgfdnraKLAALEAELAELEEELAEAEE----RLEALEAELDALQERREALQRLAEYSWDEIDV--ASAEREIAELEAE 676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  492 IEALTADIASLTEAVQQRElavtnfsqKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAE 571
Cdd:COG4913    677 LERLDASSDDLAALEEQLE--------ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                          490       500       510
                   ....*....|....*....|....*....|...
gi 1338812033  572 EWARERHEISRQQEVLMEARETISRERDAIATE 604
Cdd:COG4913    749 ALLEERFAAALGDAVERELRENLEERIDALRAR 781
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 406-585 9.32e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 9.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  406 EWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQALREQR 485
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  486 VS----------LEAQ-----------IEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKT 544
Cdd:COG3883     97 RSggsvsyldvlLGSEsfsdfldrlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1338812033  545 IQELHERVDHLGSVLNSKEEEARSNAEEWARERHEISRQQE 585
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1059-1383 1.08e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 44.06  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1059 RVVSLEQSMKVSDDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKS----EERIAQLQ 1134
Cdd:PRK04778    99 RFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFGPAldelEKQLENLE 178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1135 ARLGTASALASEKD-----SQLELLHAELKErdsLRIQAAEMEARHKELEESI-AQLQarlgtasalasekdsQLELLHA 1208
Cdd:PRK04778   179 EEFSQFVELTESGDyvearEILDQLEEELAA---LEQIMEEIPELLKELQTELpDQLQ---------------ELKAGYR 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1209 ELKErDSLRIQAAEMEARHKELEESIAQLQAQLGT-----ASVLASEKDSQLESLHaELKERdglriqaaEMEARHkELE 1283
Cdd:PRK04778   241 ELVE-EGYHLDHLDIEKEIQDLKEQIDENLALLEEldldeAEEKNEEIQERIDQLY-DILER--------EVKARK-YVE 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1284 ESIAQLQARLGTASALASGKQSELDLLHK--EVREREKLRIRAVEVE----EAQHKELEERVTEASTLASERKSQLDSLH 1357
Cdd:PRK04778   310 KNSDTLPDFLEHAKEQNKELKEEIDRVKQsyTLNESELESVRQLEKQleslEKQYDEITERIAEQEIAYSELQEELEEIL 389

                          330       340
                   ....*....|....*....|....*.
gi 1338812033 1358 NEMNEkdhvIKTQHMELESTVTQLKE 1383
Cdd:PRK04778   390 KQLEE----IEKEQEKLSEMLQGLRK 411
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1161-1348 1.13e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1161 RDSLRIQAAEMEARHKELEESIAQLQARLGTA-SALASEK--------DSQLELLHAELKErdsLRIQAAEMEARHKELE 1231
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAeAALEEFRqknglvdlSEEAKLLLQQLSE---LESQLAEARAELAEAE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1232 ESIAQLQAQLGTASVLASE--KDSQLESLHAELKErdgLRIQAAEMEARHKELEESIAQLQARLgtASALASGKQSELDL 1309
Cdd:COG3206    240 ARLAALRAQLGSGPDALPEllQSPVIQQLRAQLAE---LEAELAELSARYTPNHPDVIALRAQI--AALRAQLQQEAQRI 314

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1338812033 1310 LHKEVREREKLRIRAVEVeEAQHKELEERVTEASTLASE 1348
Cdd:COG3206    315 LASLEAELEALQAREASL-QAQLAQLEARLAELPELEAE 352
ATG16 pfam08614
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ...
 1088-1237 1.15e-03

Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.


Pssm-ID: 462536 [Multi-domain]  Cd Length: 176  Bit Score: 41.84  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1088 VTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKS-EERIAQLQARLGTASALASEKDSQLELLHAELKERDSlri 1166
Cdd:pfam08614   16 TALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSlEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK--- 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1338812033 1167 QAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELkerDSLRIQAAEMEARHKELEESIAQL 1237
Cdd:pfam08614   93 KLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDEL---VALQLQLNMAEEKLRKLEKENREL 160
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 287-536 1.17e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.15  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  287 DVLKQCQELktNKTQmerkIDDLTEEngILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQK 366
Cdd:PRK05771    20 EVLEALHEL--GVVH----IEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDV 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  367 EY----LNEQIQILQGKISILEDELSKAKAEtlgggevMGPIMEWERLNQEIADLNHK------LSQLQEIIIQLQKEKK 436
Cdd:PRK05771    92 EEelekIEKEIKELEEEISELENEIKELEQE-------IERLEPWGNFDLDLSLLLGFkyvsvfVGTVPEDKLEELKLES 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  437 EIEMMYEVEKTK------FEAEKARLEELVSELNKM----LTVQRGE--REALEQaLREQRVSLEAQIEALTADIASLTE 504
Cdd:PRK05771   165 DVENVEYISTDKgyvyvvVVVLKELSDEVEEELKKLgferLELEEEGtpSELIRE-IKEELEEIEKERESLLEELKELAK 243

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1338812033  505 AVQQRELAV----TNFSQKVD-----------------VERKRVEKLTEEMEK 536
Cdd:PRK05771   244 KYLEELLALyeylEIELERAEalskflktdktfaiegwVPEDRVKKLKELIDK 296
PRK09039 PRK09039
peptidoglycan -binding protein;
1046-1194 1.25e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1046 VMQ--LQRDLSTEQERVVSLEQSMKVSDDALihcKLEKEAlkneVTSLQELAEKLKGELEELKREHENLRLQVAETETLH 1123
Cdd:PRK09039    39 VAQffLSREISGKDSALDRLNSQIAELADLL---SLERQG----NQDLQDSVANLRASLSAAEAERSRLQALLAELAGAG 111

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033 1124 NKSEERIAQLQARLGTASALASEKDSQLELLHAELKE-RDSL-RIQAA--EMEARHKELEESIAQLQARLGTASA 1194
Cdd:PRK09039   112 AAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAAlRRQLaALEAAldASEKRDRESQAKIADLGRRLNVALA 186
EzrA COG4477
Septation ring formation regulator EzrA [Cell cycle control, cell division, chromosome ...
 421-655 1.27e-03

Septation ring formation regulator EzrA [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443574 [Multi-domain]  Cd Length: 567  Bit Score: 43.68  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  421 LSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEkarLEELVSELNKML----TVQRGEREALEQALREQRVSLEAQIEALt 496
Cdd:COG4477    199 LEQLEEELNALEELMEEIPPLLKELQTELPDQ---LEELKSGYREMKeqgyVLEHLNIEKEIEQLEEQLKEALELLEEL- 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  497 aDIASLTEAVQQRELAVTNFSQKVDVE---RKRVEKLTEEMEKQERFAQKTIQELHERVDHLGS--VLNSKEEEARSNAE 571
Cdd:COG4477    275 -DLDEAEEELEEIEEEIDELYDLLEKEveaKKYVDKNQEELEEYLEHLKEQNRELKEEIDRVQQsyRLNENELEKVRNLE 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  572 EwarerhEISRQQEVLMEARETISRERDAiateYQHFQQEKEEvackLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKV 651
Cdd:COG4477    354 K------QIEELEKRYDEIDERIEEEKVA----YSELQEELEE----IEEQLEEIEEEQEEFSEKLKSLRKDELEAREKL 419


                   ....
gi 1338812033  652 SSIE 655
Cdd:COG4477    420 DELK 423
DUF5930 pfam19353
Family of unknown function (DUF5930); This family of proteins is functionally uncharacterized. ...
 1128-1241 1.29e-03

Family of unknown function (DUF5930); This family of proteins is functionally uncharacterized. This family of proteins is found in rhodobacteria. Proteins in this family are typically between 411 and 445 amino acids in length. The family is found to the N-terminus of pfam01551.


Pssm-ID: 466052 [Multi-domain]  Cd Length: 320  Bit Score: 43.25  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1128 ERIAQLQARLgtasaLASEkDSQLEL----------LHAELKERDSLRIQAAEMEArhkELEESIAQLQARlgtasalAS 1197
Cdd:pfam19353  112 EQVSVMQSEL-----LASE-ERRRELetgieviqstLRRTMKERDAARAELAALQA---ELEGGGAAAAAR-------AA 175

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1338812033 1198 EKDSQLELLHAEL----KERDSL-------RIQAAEMEARHKELEESIAQLQAQL 1241
Cdd:pfam19353  176 DADATLDFLTAALaetaAERDQIaadaqdaLAEADELALEIRLMEERNDQIFRQL 230
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
262-789 1.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  262 EEQEQQPKEIEQLQRKNEGLLTRLHDVLKQCQELKTNKTQMERKIDDLteengilsvqmrEIFSRLSSAEAAVQKLSAEQ 341
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKL------------EKLLQLLPLYQELEALEAEL 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  342 ESSQVEWESKRGLLEsELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETLGGgevmgPIMEWERLNQEIADLNHKL 421
Cdd:COG4717    142 AELPERLEELEERLE-ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQD-----LAEELEELQQRLAELEEEL 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  422 SQLQEIIIQLQKEKKEIEMMYEVEktkfeAEKARLEELvselnKMLTVQRGEREALEQALREQRVSLEAQIEALTADIAS 501
Cdd:COG4717    216 EEAQEELEELEEELEQLENELEAA-----ALEERLKEA-----RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  502 LTeavqqreLAVTNFSQKVDVERKRVEKLtEEMEKQERFAQKTIQELHERVDHLGSVLNSKEEEARSNAEEWARERHEIS 581
Cdd:COG4717    286 LA-------LLFLLLAREKASLGKEAEEL-QALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  582 RQQEVLmeareTISRERDAIATEYQHFQQEKEEvacKLNQQIVLLEEQQsvewsllsELRKEKQELEQKVSSIEAIVdnl 661
Cdd:COG4717    358 ELEEEL-----QLEELEQEIAALLAEAGVEDEE---ELRAALEQAEEYQ--------ELKEELEELEEQLEELLGEL--- 418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  662 rtrchgLELDSEAQRASHQEEVESLKRKLHEAEsilgvyegkladhqkivEEHIALRDELSAAaecakglrdELEVERSK 741
Cdd:COG4717    419 ------EELLEALDEEELEEELEELEEELEELE-----------------EELEELREELAEL---------EAELEQLE 466

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 1338812033  742 HKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKM 789
Cdd:COG4717    467 EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
482-664 1.33e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  482 REQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQErfAQKTIQELHERVDHLGSvLNS 561
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELERLDA-SSD 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  562 KEEEARSNAEEWARERHEISRQQEVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQIVLLEEQQSVEWSLLSELR 641
Cdd:COG4913    686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                          170       180
                   ....*....|....*....|...
gi 1338812033  642 KEKQELEQKVSSIEAIVDNLRTR 664
Cdd:COG4913    766 ELRENLEERIDALRARLNRAEEE 788
PRK11637 PRK11637
AmiB activator; Provisional
 1189-1430 1.64e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 43.14  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1189 LGTASALASEKDSQLELLHAELKERD-SLRIQA---AEMEARHKELEESIAQLQAQLgtasvlaSEKDSQLESLHaelKE 1264
Cdd:PRK11637    35 LCAFSAHASDNRDQLKSIQQDIAAKEkSVRQQQqqrASLLAQLKKQEEAISQASRKL-------RETQNTLNQLN---KQ 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1265 RDGLRIQAAEMEARHKELEESIA-QLQA--RLGTASALA------SGKQSELDLLH----KEVRER--EKLRIRAVEVEe 1329
Cdd:PRK11637   105 IDELNASIAKLEQQQAAQERLLAaQLDAafRQGEHTGLQlilsgeESQRGERILAYfgylNQARQEtiAELKQTREELA- 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1330 AQHKELEERVTEASTLASERKSQLDSLHNEMNEKdhviKTQHMELESTVTQLKEQLhtatslaaVQKRVNE-KLNEDIRR 1408
Cdd:PRK11637   184 AQKAELEEKQSQQKTLLYEQQAQQQKLEQARNER----KKTLTGLESSLQKDQQQL--------SELRANEsRLRDSIAR 251

                          250       260
                   ....*....|....*....|....*
gi 1338812033 1409 LDV---VRQESMERDALRIRAIEAE 1430
Cdd:PRK11637   252 AEReakARAEREAREAARVRDKQKQ 276
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 212-685 1.71e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 43.64  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  212 LRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQR----MMRDSEEQEQQPKEIEQLQRKNEGLLT---- 283
Cdd:PRK10246   200 LEKLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQslnwLTRLDELQQEASRRQQALQQALAAEEKaqpq 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  284 -----------RLHDVLKQCQELKTNKTQMERKIDDLTEEngILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKR 352
Cdd:PRK10246   280 laalslaqparQLRPHWERIQEQSAALAHTRQQIEEVNTR--LQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDR 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  353 -GLLESELG---QALSQKEYLNEQIQILQGKISILEDELSKAKAE--TLGGGEVMGPIMEWER----------LNQEIAD 416
Cdd:PRK10246   358 fRQWNNELAgwrAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAItlTLTADEVAAALAQHAEqrplrqrlvaLHGQIVP 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  417 LNHKLSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAE-------------KARLEELVSELNKM----------------- 466
Cdd:PRK10246   438 QQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKtqqladvkticeqEARIKDLEAQRAQLqagqpcplcgstshpav 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  467 -------LTVQRGEREALEQ---ALREQRVSLEAQIEALTADIASLTEAVQ---QRELAVTNFSQKV----DVERKRVEK 529
Cdd:PRK10246   518 eayqalePGVNQSRLDALEKevkKLGEEGAALRGQLDALTKQLQRDESEAQslrQEEQALTQQWQAVcaslNITLQPQDD 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  530 LTEEMEKQERFAQKTIQeLHERVDhLGSVLNSKEEEARSNAEEWARERHEISRQQEVLM------EARETISRERdaiAT 603
Cdd:PRK10246   598 IQPWLDAQEEHERQLRL-LSQRHE-LQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYAltlpqeDEEASWLATR---QQ 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  604 EYQHFQQEKEEVAcKLNQQIVLLEeqqsvewSLLSELrkeKQELEQKVSSIEAIVDNLR---TRChgLELDSEAQRASHQ 680
Cdd:PRK10246   673 EAQSWQQRQNELT-ALQNRIQQLT-------PLLETL---PQSDDLPHSEETVALDNWRqvhEQC--LSLHSQLQTLQQQ 739


                   ....*
gi 1338812033  681 EEVES 685
Cdd:PRK10246   740 DVLEA 744
PRK01156 PRK01156
chromosome segregation protein; Provisional
 214-504 1.78e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.35  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  214 KLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQLQRKneglltrLHDVLKQCQ 293
Cdd:PRK01156   149 AQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKS-------HSITLKEIE 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  294 ELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLNE-- 371
Cdd:PRK01156   222 RLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDyf 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  372 ----QIQILQGKISILEDELSKAKAETLGGGEVMGPIMEWERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMyeveKT 447
Cdd:PRK01156   302 kyknDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESL----KK 377

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  448 KFEAEKARLEELVSELNKMLTVQRGEREALEQALREQRVSL---EAQIEALTADIASLTE 504
Cdd:PRK01156   378 KIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLqdiSSKVSSLNQRIRALRE 437
mukB PRK04863
chromosome partition protein MukB;
1071-1409 1.79e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1071 DDALIHCKLEKEALKNEVTSLQELAEKLKGELEELKREHENL---------RLQVAETETLHNKSEER----IAQLQARL 1137
Cdd:PRK04863   285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLeqdyqaasdHLNLVQTALRQQEKIERyqadLEELEERL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1138 GTASALASEKDSQlellhaelkeRDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLhaelkERDSLR 1217
Cdd:PRK04863   365 EEQNEVVEEADEQ----------QEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQAL-----ERAKQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1218 IQAAEMEArhKELEESIAQLQAQlgtasvlasEKDSQLESLHAELKerdgLRIQAAemearHKELEESIAQLQARLGTAS 1297
Cdd:PRK04863   430 CGLPDLTA--DNAEDWLEEFQAK---------EQEATEELLSLEQK----LSVAQA-----AHSQFEQAYQLVRKIAGEV 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1298 ALASGKQSELDLLhkevREREKLRIRAVEVE--EAQHKELEERVTEASTlASERKSQLDSLHNEMNEKDHVIKTQHMELE 1375
Cdd:PRK04863   490 SRSEAWDVARELL----RRLREQRHLAEQLQqlRMRLSELEQRLRQQQR-AERLLAEFCKRLGKNLDDEDELEQLQEELE 564

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1338812033 1376 STVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRL 1409
Cdd:PRK04863   565 ARLESLSESVSEARERRMALRQQLEQLQARIQRL 598
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 319-512 1.82e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  319 QMREIFSRLSSAEAAVQKLSAEQEssqvEWESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAetlggg 398
Cdd:COG1579     18 ELDRLEHRLKELPAELAELEDELA----ALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN------ 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  399 evmgpimewerlNQEIADLNHKLSQLQEIIIQLqkEKKEIEMMYEVE--KTKFEAEKARLEELVSELnkmltvqrgerEA 476
Cdd:COG1579     88 ------------NKEYEALQKEIESLKRRISDL--EDEILELMERIEelEEELAELEAELAELEAEL-----------EE 142

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1338812033  477 LEQALREQRVSLEAQIEALTADIASLTEAVQQRELA 512
Cdd:COG1579    143 KKAELDEELAELEAELEELEAEREELAAKIPPELLA 178
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
349-537 1.85e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  349 ESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSK-AKAETLGGGE--VMGPIMEWERLNQEIADL---NHKLS 422
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlQRLAEYSWDEidVASAEREIAELEAELERLdasSDDLA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  423 QLQEIIIQLQKEKKEIEMmyevEKTKFEAEKARLEElvsELNKMLTVQRGEREALEQALREQRVSLEAQIEALTADIasL 502
Cdd:COG4913    689 ALEEQLEELEAELEELEE----ELDELKGEIGRLEK---ELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAA--L 759

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1338812033  503 TEAVQQRelAVTNFSQKVDVERKRVEKLTEEMEKQ 537
Cdd:COG4913    760 GDAVERE--LRENLEERIDALRARLNRAEEELERA 792
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1109-1341 1.91e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 43.14  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1109 HENLRLQVAETETLHNKSEERIAQLQARlgtasalASEKDSQLELLHAELKERDSLRIQA---AEMEARHKELeESIAQL 1185
Cdd:COG0497    153 LEELLEEYREAYRAWRALKKELEELRAD-------EAERARELDLLRFQLEELEAAALQPgeeEELEEERRRL-SNAEKL 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1186 QARLGTA-SALASEKDSQLELLHAELKERDSLriqaAEMEARHKELEESIAQLQAQLG-TASVLASEKDS------QLES 1257
Cdd:COG0497    225 REALQEAlEALSGGEGGALDLLGQALRALERL----AEYDPSLAELAERLESALIELEeAASELRRYLDSlefdpeRLEE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1258 LHAELKERDGL----RIQAAEMEARHKELEESIAQLQARLGTASALasgkQSELDLLHKEVRER-EKL---RIRAVevee 1329
Cdd:COG0497    301 VEERLALLRRLarkyGVTVEELLAYAEELRAELAELENSDERLEEL----EAELAEAEAELLEAaEKLsaaRKKAA---- 372

                          250
                   ....*....|..
gi 1338812033 1330 aqhKELEERVTE 1341
Cdd:COG0497    373 ---KKLEKAVTA 381
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 1164-1342 2.09e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 42.41  E-value: 2.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1164 LRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQLGT 1243
Cdd:pfam00529   49 FQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLAR 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1244 ASVLASekdsqleslhaelkerDGLRIQAAEMEARhkeleESIAQLQARLGTASALASGKQSELDLLHKEVRereKLRIR 1323
Cdd:pfam00529  129 RRVLAP----------------IGGISRESLVTAG-----ALVAQAQANLLATVAQLDQIYVQITQSAAENQ---AEVRS 184

                          170
                   ....*....|....*....
gi 1338812033 1324 AVEVEEAQHKELEERVTEA 1342
Cdd:pfam00529  185 ELSGAQLQIAEAEAELKLA 203
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1062-1164 2.21e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1062 SLEQSMKVSDDALIHCKLEKEALKNEV-TSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQARLGTA 1140
Cdd:COG0542    408 SKPEELDELERRLEQLEIEKEALKKEQdEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKI 487

                           90       100
                   ....*....|....*....|....
gi 1338812033 1141 SALasekDSQLELLHAELKERDSL 1164
Cdd:COG0542    488 PEL----EKELAELEEELAELAPL 507
CH pfam00307
Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal ...
 8-44 2.38e-03

Calponin homology (CH) domain; The CH domain is found in both cytoskeletal proteins and signal transduction proteins. The CH domain is involved in actin binding in some members of the family. However in calponins there is evidence that the CH domain is not involved in its actin binding activity. Most member proteins have from two to four copies of the CH domain, however some proteins such as calponin have only a single copy.


Pssm-ID: 425596 [Multi-domain]  Cd Length: 109  Bit Score: 39.58  E-value: 2.38e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1338812033    8 EEALLNWINSlHLDSPIDHIFL------LQDGVILVKLIHKLK 44
Cdd:pfam00307    4 EKELLRWINS-HLAEYGPGVRVtnfttdLRDGLALCALLNKLA 45
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1296-1540 2.39e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1296 ASALASGKQSELDLLHKEVREREKLRIRAveveEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHVIKtqhmELE 1375
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAAL----KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA----ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1376 STVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDALRIRAIEAEDLKRKEMEETIVKLKSEILTHTTKL 1455
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1456 EHlnkwHQQQLSVLRNENQTLlsmKESMVKEQEVSQRVKVSLESKLKLAGQELSVllpLQECKAENERLIGDLQEQLQAK 1535
Cdd:COG4942    170 EA----ERAELEALLAELEEE---RAALEALKAERQKLLARLEKELAELAAELAE---LQQEAEELEALIARLEAEAAAA 239


                   ....*
gi 1338812033 1536 TEAMK 1540
Cdd:COG4942    240 AERTP 244
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1176-1278 2.46e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1176 KELEESIAQLQARLgtaSALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQAQlgtasvlASEKDSQL 1255
Cdd:PRK11448   145 HALQQEVLTLKQQL---ELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEK-------AAETSQER 214

                           90       100
                   ....*....|....*....|...
gi 1338812033 1256 ESLHAELKERDGLRIQAAEMEAR 1278
Cdd:PRK11448   215 KQKRKEITDQAAKRLELSEEETR 237
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 422-954 2.46e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  422 SQLQEIIIQLQKEKKEIEMMYEVEKTKFEAEKARLEelVSELNKMLTVQRGEREALEQALREqrvsLEAQIEALTADIAS 501
Cdd:pfam10174  192 MQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAK--TKALQTVIEMKDTKISSLERNIRD----LEDEVQMLKTNGLL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  502 LTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELH----------ERVDHLGSVLNSKEEEARSNAE 571
Cdd:pfam10174  266 HTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLEtltnqnsdckQHIEVLKESLTAKEQRAAILQT 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  572 EWARERHEISRQQEVLMEARETISR---ERDAIATEYQHFQQE---KEEVACKLNQQIVLLEEQQSVEWSLLSELRKEKQ 645
Cdd:pfam10174  346 EVDALRLRLEEKESFLNKKTKQLQDlteEKSTLAGEIRDLKDMldvKERKINVLQKKIENLQEQLRDKDKQLAGLKERVK 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  646 ELEQKVSSI--------EAIVDNLRTrCHGLELDSEAQRASHQEEVESLKRKLHEAESILGVYEGKLADHQKIVEEHIAL 717
Cdd:pfam10174  426 SLQTDSSNTdtalttleEALSEKERI-IERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEH 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  718 RDELSAAAECAKGLRDELEVERSKHKETlAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAK 797
Cdd:pfam10174  505 ASSLASSGLKKDSKLKSLEIAVEQKKEE-CSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVER 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  798 LIEEGREVE-------RGLTAARDQAFLTIKEREAETSKLRSEAEALSSKVI-LAEEAKAIELAKKDDEMQvlsKEMKQI 869
Cdd:pfam10174  584 LLGILREVEnekndkdKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAqLLEEARRREDNLADNSQQ---LQLEEL 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  870 QMELGTVKKAKDDMELDL---QSSIEKRQEQLLVLRF----QMNELEESANQ--------KETEIEVLQTKLSNKDEELK 934
Cdd:pfam10174  661 MGALEKTRQELDATKARLsstQQSLAEKDGHLTNLRAerrkQLEEILEMKQEallaaiseKDANIALLELSSSKKKKTQE 740

                          570       580
                   ....*....|....*....|
gi 1338812033  935 AFCLHeKVEREELQRQLKQE 954
Cdd:pfam10174  741 EVMAL-KREKDRLVHQLKQQ 759
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 410-692 2.46e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 43.25  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  410 LNQEIADLNHK----LSQLQEIIIQLQKEKKEIEMMYEVEKTKFEAekarLEELVSELNKMLTVQR------GEREALEQ 479
Cdd:PRK10246   535 LEKEVKKLGEEgaalRGQLDALTKQLQRDESEAQSLRQEEQALTQQ----WQAVCASLNITLQPQDdiqpwlDAQEEHER 610

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  480 ALRE--QRVSLEAQIEALTADIASLTEAVQQRELAVTN----FSQKVDVERKRVEKLTEEMEKQERFAQKT--IQELHER 551
Cdd:PRK10246   611 QLRLlsQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTalagYALTLPQEDEEASWLATRQQEAQSWQQRQneLTALQNR 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  552 VDHLGSVLNS-------KEEEARSNAEEWaRERHE----------ISRQQEVLMEARETISRERDAIATEYQHFQQEKEE 614
Cdd:PRK10246   691 IQQLTPLLETlpqsddlPHSEETVALDNW-RQVHEqclslhsqlqTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAF 769

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1338812033  615 VACKLNQQIVLLEEQQSveWSLLSELRKEKQELEQkvsSIEAIVDNLRTRCHGLELDSEAQRAshQEEVESLKRKLHE 692
Cdd:PRK10246   770 LAALLDEETLTQLEQLK--QNLENQRQQAQTLVTQ---TAQALAQHQQHRPDGLDLTVTVEQI--QQELAQLAQQLRE 840
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 202-456 2.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  202 QDVLNTPQFRLRKLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQqpkEIEQLQRKNEGL 281
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA---ELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  282 LTRLHDVLKQCQELKTNKTQMERKIDDLTEENGILSVQMREIFSRLSSAEAAVQKLSAEQESSQVEWESKRGLLESELGQ 361
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  362 ALSQKEYLNEQIQILQGKISILEDELSKAKAETlgggevmgpimewERLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMm 441
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKEL-------------AELAAELAELQQEAEELEALIARLEAEAAAAAE- 241

                          250
                   ....*....|....*
gi 1338812033  442 yEVEKTKFEAEKARL 456
Cdd:COG4942    242 -RTPAAGFAALKGKL 255
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 328-585 2.70e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  328 SSAEAAVQKLSAEQESSQVEWESKRGLLESELGQALSQKEYLNEQIQILQGKISILEDELSKAKAETlgggevmgpimew 407
Cdd:COG3883      1 ALALALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI------------- 67

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  408 ERLNQEIADLNHKLSQLQEIIIQ----LQKEKKEIEMMYEVektkFEAEKarLEELVSELNKMLTVQRGEREALEQaLRE 483
Cdd:COG3883     68 DKLQAEIAEAEAEIEERREELGEraraLYRSGGSVSYLDVL----LGSES--FSDFLDRLSALSKIADADADLLEE-LKA 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  484 QRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLteemEKQERFAQKTIQELHERVDHLGSVLNSKE 563
Cdd:COG3883    141 DKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQL----SAEEAAAEAQLAELEAELAAAEAAAAAAA 216

                          250       260
                   ....*....|....*....|..
gi 1338812033  564 EEARSNAEEWARERHEISRQQE 585
Cdd:COG3883    217 AAAAAAAAAAAAAAAAAAAAAA 238
CH_PLS_FIM_rpt3 cd21219
third calponin homology (CH) domain found in the plastin/fimbrin family; This family includes ...
 8-44 2.84e-03

third calponin homology (CH) domain found in the plastin/fimbrin family; This family includes plastin and fimbrin. Plastin has three isoforms, plastin-1, -2, and -3. Plastin-1, also called intestine-specific plastin, or I-plastin, is an actin-bundling protein in the absence of calcium. Plastin-2, also called L-plastin, or LC64P, or lymphocyte cytosolic protein 1 (LCP-1), is an actin-binding protein that plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. It modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-3, also called T-plastin, is an actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. It may play a role in the regulation of bone development. Fimbrin has been found in plants and fungi. Arabidopsis thaliana fimbrin (AtFIM) includes fimbrin-1, -2, -3, -4, and -5, which cross-link actin filaments (F-actin) in a calcium independent manner. They stabilize and prevent F-actin depolymerization mediated by profilin. They act as key regulators of actin cytoarchitecture, probably involved in cell cycle, cell division, cell elongation and cytoplasmic tractus. AtFIM5 is an actin bundling factor that is required for pollen germination and pollen tube growth. Fungal fimbrin binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity. Members of this family contain four copies of the CH domain. This model corresponds to the third CH domain. CH domains are actin filament (F-actin) binding motifs.


Pssm-ID: 409068  Cd Length: 113  Bit Score: 39.57  E-value: 2.84e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1338812033    8 EEALLNWINSLHLDSPIDHIFL-LQDGVILVKLIHKLK 44
Cdd:cd21219      6 ERAFRMWLNSLGLDPLINNLYEdLRDGLVLLQVLDKIQ 43
CH smart00033
Calponin homology domain; Actin binding domains present in duplicate at the N-termini of ...
 9-70 3.12e-03

Calponin homology domain; Actin binding domains present in duplicate at the N-termini of spectrin-like proteins (including dystrophin, alpha-actinin). These domains cross-link actin filaments into bundles and networks. A calponin homology domain is predicted in yeasst Cdc24p.


Pssm-ID: 214479 [Multi-domain]  Cd Length: 101  Bit Score: 39.22  E-value: 3.12e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033     9 EALLNWINS-LHLDSPIDHIFL---LQDGVILVKLIHKLKKQEIGVDAVLELPLQ-GRLDFISAFLQ 70
Cdd:smart00033    1 KTLLRWVNSlLAEYDKPPVTNFssdLKDGVALCALLNSLSPGLVDKKKVAASLSRfKKIENINLALS 67
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 479-694 3.23e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  479 QALREQRVSLEAQIEALTADIASLTEAVQQRElavtnfsqkvdVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSV 558
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALK-----------KEEKALLKQLAALERRIAALARRIRALEQELAALEAE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  559 LNSKEEEARSNAEEWARERHEISRQQEVL------------------------MEARETISRERDAIATEYQHFQQEkee 614
Cdd:COG4942     85 LAELEKEIAELRAELEAQKEELAELLRALyrlgrqpplalllspedfldavrrLQYLKYLAPARREQAEELRADLAE--- 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  615 vackLNQQIVLLEEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRchglELDSEAQRASHQEEVESLKRKLHEAE 694
Cdd:COG4942    162 ----LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKE----LAELAAELAELQQEAEELEALIARLE 233
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 627-923 3.32e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  627 EEQQSVEWSLLSELRKEKQELEQKVSSIEAIVDNLRTRchGLELDSEAQRASHQEEVESLKRKlhEAESILgvYEGKLAD 706
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKAR--QAEMDRQAAIYAEQERMAMERER--ELERIR--QEERKRE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  707 HQKIVEEHIALrdELSAAAECakglrDELEVERSKHKETLAAKLQSKSQMMEEMRELEEKTQNMSVEMQHLGQQLSKVQQ 786
Cdd:pfam17380  362 LERIRQEEIAM--EISRMREL-----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  787 EKMRV-DASMAKLIEEGREVERgltaARDQAFLTIKEREAETSKLRSEAEALSSKVILAEEA--KAIELAKKDDEMQVLS 863
Cdd:pfam17380  435 REVRRlEEERAREMERVRLEEQ----ERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQrrKILEKELEERKQAMIE 510

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1338812033  864 KEMKQ--IQMELGTVKKAKDDMELDLQSSIEKRQEQLLVLRFQMNELEESANQKETEIEVLQ 923
Cdd:pfam17380  511 EERKRklLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME 572
mukB PRK04863
chromosome partition protein MukB;
446-1261 4.12e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  446 KTKFEAEKARLEELVSELnkmlTVQRGEREALEQAL-----REQRVsLEA-----QIEALTADIASLTEAVQQRELAVTN 515
Cdd:PRK04863   299 RRQLAAEQYRLVEMAREL----AELNEAESDLEQDYqaasdHLNLV-QTAlrqqeKIERYQADLEELEERLEEQNEVVEE 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  516 FSQKVDVERKRVEKLTEEMEK--------QERF--AQKTIQELHERVDHLGSV--LNSKEEEARSNAEEWARERHeiSRQ 583
Cdd:PRK04863   374 ADEQQEENEARAEAAEEEVDElksqladyQQALdvQQTRAIQYQQAVQALERAkqLCGLPDLTADNAEDWLEEFQ--AKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  584 QEVLMEARETISRERDAIATEYQHfqqekeEVACKLNQQI---VLLEEQQSVEWSLLSELRKEKQELEQkvssieaiVDN 660
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQF------EQAYQLVRKIageVSRSEAWDVARELLRRLREQRHLAEQ--------LQQ 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  661 LRTRCHGLELDSEAQRashqeeveSLKRKLHEAESILGVYEGKLADHQKIVEEHIALRDELSAAAECAKGLRDELEVERS 740
Cdd:PRK04863   518 LRMRLSELEQRLRQQQ--------RAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLE 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  741 KHKEtLAAKLQSKSQmmeemreleeKTQNMSVEMQHLGQQLSKVQQEKMRVDASMAKLIEEGRE--VERGLTAARDQAFL 818
Cdd:PRK04863   590 QLQA-RIQRLAARAP----------AWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLEREREltVERDELAARKQALD 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  819 TIKER-----EAETSKLRSEAEALSSkVILAE-----------------------------EAKAIELAKKDD------- 857
Cdd:PRK04863   659 EEIERlsqpgGSEDPRLNALAERFGG-VLLSEiyddvsledapyfsalygparhaivvpdlSDAAEQLAGLEDcpedlyl 737

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  858 -------------EMQVLSK----EMKQIQMELGTV-------KKAKDDMELDLQSSIEKRQEQLLVLRFQMNELE---E 910
Cdd:PRK04863   738 iegdpdsfddsvfSVEELEKavvvKIADRQWRYSRFpevplfgRAAREKRIEQLRAEREELAERYATLSFDVQKLQrlhQ 817

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  911 SANQ-------------KETEIEVLQTKLSNKDEELKAfclHEKVEREeLQRQLKQEEDRCLMYKQeivvkdkevnFLKM 977
Cdd:PRK04863   818 AFSRfigshlavafeadPEAELRQLNRRRVELERALAD---HESQEQQ-QRSQLEQAKEGLSALNR----------LLPR 883

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  978 AMVAKEEEINSLMQSIHSGEEKA-SAFQDLQEkrheeQKQAISTLEIRLSdahrLLEEKASSIEMQTSQVMQLQRDLSTE 1056
Cdd:PRK04863   884 LNLLADETLADRVEEIREQLDEAeEAKRFVQQ-----HGNALAQLEPIVS----VLQSDPEQFEQLKQDYQQAQQTQRDA 954

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1057 QERVVSLEQSMKVSDdaliHCKLEKEAlkNEVTSLQELAEKLKGELEELKREHENLRLQVAETETLHNKSEERIAQLQar 1136
Cdd:PRK04863   955 KQQAFALTEVVQRRA----HFSYEDAA--EMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLK-- 1026

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1137 lgtasalaSEKDSQLELLHAELKERDSLRIQA-AEMEARHKELEEsiaQLQARLGTASALASEKDSQLELLHAELkerDS 1215
Cdd:PRK04863  1027 --------SSYDAKRQMLQELKQELQDLGVPAdSGAEERARARRD---ELHARLSANRSRRNQLEKQLTFCEAEM---DN 1092

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1338812033 1216 LRIQAAEMEARHKELEESIaqLQAQLGTASVLASEKDSQLES-LHAE 1261
Cdd:PRK04863  1093 LTKKLRKLERDYHEMREQV--VNAKAGWCAVLRLVKDNGVERrLHRR 1137
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1271-1585 5.11e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1271 QAAEMEaRHKELEESIAQLQARLGTASA-------LASGKQSELDLLHKEVREREKLRIRAVEVeeaqhkeleervteas 1343
Cdd:pfam17380  308 KAREVE-RRRKLEEAEKARQAEMDRQAAiyaeqerMAMERERELERIRQEERKRELERIRQEEI---------------- 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1344 TLASERKSQLDSLHNEMNEKDHviktqhmelestvtQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMERDALR 1423
Cdd:pfam17380  371 AMEISRMRELERLQMERQQKNE--------------RVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQRE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1424 IRAIEAEdlKRKEMEEtivklkseilthtTKLEHLNKwhQQQLSVLRNENQTLLSMKESMVKEQEVSQRVKvslESKLKL 1503
Cdd:pfam17380  437 VRRLEEE--RAREMER-------------VRLEEQER--QQQVERLRQQEEERKRKKLELEKEKRDRKRAE---EQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1504 AGQELSV-LLPLQECKAENERLIGDLQEQLQAKTEAMKHCKAQVQMAKTHYNGKKQQLLEVQEKAQTLENTLESRDQEVK 1582
Cdd:pfam17380  497 LEKELEErKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE 576


                   ...
gi 1338812033 1583 VLR 1585
Cdd:pfam17380  577 MMR 579
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 1195-1308 5.40e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 41.28  E-value: 5.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1195 LASEKDSQLELLHAELKERDSLRIQAAEMEARHKE----LEESIAQLQAQLGTASVLASEKDSQLESLHAELKE-RDGLR 1269
Cdd:pfam09787   52 LRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEeaesSREQLQELEEQLATERSARREAEAELERLQEELRYlEEELR 131

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1338812033 1270 IQAAEMEARHKELEESIAQLQARLgTASALASGKQSELD 1308
Cdd:pfam09787  132 RSKATLQSRIKDREAEIEKLRNQL-TSKSQSSSSQSELE 169
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 211-623 5.59e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 5.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  211 RLRKLQKQLVQE------------REMRDEL-ERELASRSQVITEREMQVSQlQHRVQRMMRDSEEQEQQPKEIEQLQRK 277
Cdd:COG3096    253 SDRDLFKHLITEatnyvaadymrhANERRELsERALELRRELFGARRQLAEE-QYRLVEMARELEELSARESDLEQDYQA 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  278 NEGLLTRLHDVLKQcQElktnktQMERKIDDLTEENGILSVQMREIfsrlssAEAAVQKLSAEQESSQVEWESKRglLES 357
Cdd:COG3096    332 ASDHLNLVQTALRQ-QE------KIERYQEDLEELTERLEEQEEVV------EEAAEQLAEAEARLEAAEEEVDS--LKS 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  358 ELG---QALS--QKEYLNEQiQILQgkisiledelSKAKAETLGGgevmGPIMEWERLNQEIADLNHKLSQLQEIIIQLQ 432
Cdd:COG3096    397 QLAdyqQALDvqQTRAIQYQ-QAVQ----------ALEKARALCG----LPDLTPENAEDYLAAFRAKEQQATEEVLELE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  433 KEKKeiemMYEVEKTKFEAEKARLEELVSElnkmltVQRGE-----REALEQAlREQRvSLEAQIEALTADIASLTEAVQ 507
Cdd:COG3096    462 QKLS----VADAARRQFEKAYELVCKIAGE------VERSQawqtaRELLRRY-RSQQ-ALAQRLQQLRAQLAELEQRLR 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  508 QRELAV---TNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVDHLGSV------LNSKEEEARSNAEEW--ARE 576
Cdd:COG3096    530 QQQNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELrqqleqLRARIKELAARAPAWlaAQD 609

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033  577 RHEISRQQ--------EVLMEARET-ISRERDAIATEyQHFQQEKEEvackLNQQI 623
Cdd:COG3096    610 ALERLREQsgealadsQEVTAAMQQlLEREREATVER-DELAARKQA----LESQI 660
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 999-1413 6.11e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.66  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  999 KASAFQDLQEKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQLQRDLSTEQ-------------ERVVSLEQ 1065
Cdd:pfam07111   13 QSPGHQDVLERRLDTQRPTVTMWEQDVSGDGQGPGRRGRSLELEGSQALSQQAELISRQlqelrrleeevrlLRETSLQQ 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1066 SMKVSDDAlihckLEKEALKNEVTSLQELAEKLKGELEELKREHENL----RLQVAETETLHNksEERIAQLQARLGTAS 1141
Cdd:pfam07111   93 KMRLEAQA-----MELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLeegsQRELEEIQRLHQ--EQLSSLTQAHEEALS 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1142 ALASEKD------SQLELLHAelKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALAS-----------------E 1198
Cdd:pfam07111  166 SLTSKAEglekslNSLETKRA--GEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKyvgeqvppevhsqtwelE 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1199 KDSQLELLHAELKERDSLRIQAAEMEARHKELEESIA----QLQAQLGTASVLASEKDSQLESLHAELKERdgLRIQAAE 1274
Cdd:pfam07111  244 RQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLAlqeeELTRKIQPSDSLEPEFPKKCRSLLNRWREK--VFALMVQ 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1275 MEARHKELEESIAQLQARLGTASALASGKQSELDLLHKEVREREKlrirAVEVEEAQHKELEERVTEASTLASERKSQLD 1354
Cdd:pfam07111  322 LKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAA----EVEVERMSAKGLQMELSRAQEARRRQQQQTA 397

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1338812033 1355 SLHNEMNEKDHVIKTQHMELESTVTQLKEQLHTATSLaavqkrvNEKLNEDIRRLDVVR 1413
Cdd:pfam07111  398 SAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSL-------SNRLSYAVRKVHTIK 449
mukB PRK04863
chromosome partition protein MukB;
218-623 6.71e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 6.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  218 QLVQEREMRDELERELA--------SRSQVITEREmQVSQLQHRVQRMM-----------RDSEEQEQQPKEIEQLQRKN 278
Cdd:PRK04863   838 ELRQLNRRRVELERALAdhesqeqqQRSQLEQAKE-GLSALNRLLPRLNlladetladrvEEIREQLDEAEEAKRFVQQH 916

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  279 EGLLTRL-------------HDVLKQ-CQELKTNKTQMERKIDDLTEengilSVQMREIFSRlssaEAAVQKLSAEQESS 344
Cdd:PRK04863   917 GNALAQLepivsvlqsdpeqFEQLKQdYQQAQQTQRDAKQQAFALTE-----VVQRRAHFSY----EDAAEMLAKNSDLN 987

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  345 QveweskrgLLESELGQALSQKEYLNEQIQILQgkisileDELSKAkaetlgggevmgpimewerlNQEIADLNHKLSQL 424
Cdd:PRK04863   988 E--------KLRQRLEQAEQERTRAREQLRQAQ-------AQLAQY--------------------NQVLASLKSSYDAK 1032

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  425 QEIIIQLQKEKKEIEMMYEVEktkfEAEKARLEElvSELNKMLTVQRGEREALEQalreQRVSLEAQIEALTADIASLTE 504
Cdd:PRK04863  1033 RQMLQELKQELQDLGVPADSG----AEERARARR--DELHARLSANRSRRNQLEK----QLTFCEAEMDNLTKKLRKLER 1102

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  505 A-VQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVD--------------HLGSVLNSKEEEAR-- 567
Cdd:PRK04863  1103 DyHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRELAYLSADELRSMSDkalgalrlavadneHLRDVLRLSEDPKRpe 1182

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1338812033  568 ------SNAEEWARER--HEISRQQ---EVLMEARETISRERDAIATEYQHFQQEKEEVACKLNQQI 623
Cdd:PRK04863  1183 rkvqfyIAVYQHLRERirQDIIRTDdpvEAIEQMEIELSRLTEELTSREQKLAISSESVANIIRKTI 1249
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1213-1414 6.88e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 6.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1213 RDSLRIQAAEMEARHKELEESIAQLQAQLgtasvlaSEKDSQLESLHAELK------ERDGLRIQAAEMEARHKELEESI 1286
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNGlvdlseEAKLLLQQLSELESQLAEARAEL 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1287 AQLQARLGTA-SALASGKQSELDLLHKEVREREKLRIRAVEVEEAqhkELEERVTEAS----TLASERKSQLDSLHNEMN 1361
Cdd:COG3206    236 AEAEARLAALrAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA---ELSARYTPNHpdviALRAQIAALRAQLQQEAQ 312

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1338812033 1362 EKDHVIKTQHMELESTVTQLKEQLHTATSLAAVQKRVNEKLNEDIRRLDVVRQ 1414
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 1125-1272 7.47e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 40.87  E-value: 7.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1125 KSEERIAQLQARLGTASALASEKDSQLELLHAELKERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKD-SQL 1203
Cdd:pfam00529   62 SAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGiSRE 141

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1204 ELLHAELkerdslriQAAEMEARHKELEESIAQLQAQ-LGTASVLASEKDSQLESLHAELKERDGLRIQA 1272
Cdd:pfam00529  142 SLVTAGA--------LVAQAQANLLATVAQLDQIYVQiTQSAAENQAEVRSELSGAQLQIAEAEAELKLA 203
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 214-542 7.89e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 7.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  214 KLQKQLVQEREMRDELERELASRSQVITEREMQVSQLQHRVQRMMRDSEEQEQQPKEIEQ----LQRKN---EGLLTRLH 286
Cdd:COG3096    344 RQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQaldvQQTRAiqyQQAVQALE 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  287 DVLKQCQE-------LKTNKTQMERKIDDLTEEngilsvqMREIFSRLSSAEAA----------VQKLSAEQESSQVeWE 349
Cdd:COG3096    424 KARALCGLpdltpenAEDYLAAFRAKEQQATEE-------VLELEQKLSVADAArrqfekayelVCKIAGEVERSQA-WQ 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  350 SKRGLLEselgQALSQKeYLNEQIQILQGKISILEdelskakaetlgggevmgpimewERLNQEiadlnHKLSQLQEIII 429
Cdd:COG3096    496 TARELLR----RYRSQQ-ALAQRLQQLRAQLAELE-----------------------QRLRQQ-----QNAERLLEEFC 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  430 QLQKEKKEIEMMYEVEKTKFEAEKARLEELVSELNKMLTVQRGEREALEQ-------------ALREQRVSLEAQIEALT 496
Cdd:COG3096    543 QRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRArikelaarapawlAAQDALERLREQSGEAL 622

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1338812033  497 ADIASLTEAVQQ---RELAVTnfsqkvdVERKRVEKLTEEMEKQ-ERFAQ 542
Cdd:COG3096    623 ADSQEVTAAMQQlleREREAT-------VERDELAARKQALESQiERLSQ 665
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1160-1352 7.94e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 7.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1160 ERDSLRIQAAEMEARHKELEESIAQLQARLGTASALASEKDSQLELLHAELkerDSLRIQAAEMEA----RHKELEESIA 1235
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI---DKLQAEIAEAEAeieeRREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1236 QLQAQLGTAS----VLASE---------------KDSQLESLHAELKERDGLRIQAAEMEARHKELEESIAQLQARLGTA 1296
Cdd:COG3883     94 ALYRSGGSVSyldvLLGSEsfsdfldrlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1338812033 1297 SALASGKQSELDLLHKEVREREKLRIRAVEVEEAQHKELEERVTEASTLASERKSQ 1352
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1008-1137 8.95e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 8.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1008 EKRHEEQKQAISTLEIRLSDAHRLLEEKASSIEMQTSQVMQL--QRDLSTEQERVVSLEQSMKVSDDALIHCKLEKEALK 1085
Cdd:COG1579     44 EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQKEIESLKRRISDLEDEILELMERIEELE 123

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1338812033 1086 NEVTSLQELAEKLKGELEELKREhenLRLQVAETETLHNKSEERIAQLQARL 1137
Cdd:COG1579    124 EELAELEAELAELEAELEEKKAE---LDEELAELEAELEELEAEREELAAKI 172
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1228-1471 9.58e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1228 KELEESIAQLQAQLGTasvlasekdsqLESLHAELKE----RDGLRiQAAEMEARHKELEESIAQLQARLGTASALASgk 1303
Cdd:COG4913    221 PDTFEAADALVEHFDD-----------LERAHEALEDareqIELLE-PIRELAERYAAARERLAELEYLRAALRLWFA-- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1304 QSELDLLHKEVREreklriravevEEAQHKELEERVTEASTLASERKSQLDSLHNEMNEKDHviktqhmeleSTVTQLKE 1383
Cdd:COG4913    287 QRRLELLEAELEE-----------LRAELARLEAELERLEARLDALREELDELEAQIRGNGG----------DRLEQLER 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033 1384 QLHTATSLAAVQKRVNEKLNEDIRRLDVVRQESMER-DALRIRA---IEAEDLKRKEMEETIVKLKSEILTHTTKLEHLn 1459
Cdd:COG4913    346 EIERLERELEERERRRARLEALLAALGLPLPASAEEfAALRAEAaalLEALEEELEALEEALAEAEAALRDLRRELREL- 424

                          250
                   ....*....|..
gi 1338812033 1460 kwhQQQLSVLRN 1471
Cdd:COG4913    425 ---EAEIASLER 433
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 409-553 9.71e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 9.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  409 RLNQEIADLNHKLSQLQEIIIQLQKEKKEIEMMYEVEKT---KFEAEKARLEELVSELNKMLTVQRG---------EREA 476
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTeleDLEKEIKRLELEIEEVEARIKKYEEqlgnvrnnkEYEA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1338812033  477 LE---QALREQRVSLEAQIEALTADIASLTEAVQQRELAVTNFSQKVDVERKRVEKLTEEMEKQERFAQKTIQELHERVD 553
Cdd:COG1579     94 LQkeiESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH