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Conserved domains on  [gi|2462510911|ref|XP_054193411|]
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proton-activated chloride channel isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMEM206 super family cl20991
TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has ...
 1-135 1.88e-93

TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has not, as yet, been determined. Members of this family are remain uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are approximately 350 amino acids in length.


The actual alignment was detected with superfamily member pfam15122:

Pssm-ID: 434477  Cd Length: 296  Bit Score: 271.66  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510911   1 MAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHY-EVIPPLTSPGQPGDMNCTTQRINY 79
Cdd:pfam15122  24 MAVAVFLAYQTITDFREKLKHPVMSVSYKEVDSYDAPGIALYPGKAQLLSCKHHYhDHIPPLVDPGQPGEIDCVTEEINY 103

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510911  80 TDPFSNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQ 135
Cdd:pfam15122 104 TDPFTNQTEKHALVVRGPSDVRKRELVFLQFSLNETEEDFSAISYLLFSSFQEFLD 159
 
Name Accession Description Interval E-value
TMEM206 pfam15122
TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has ...
 1-135 1.88e-93

TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has not, as yet, been determined. Members of this family are remain uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are approximately 350 amino acids in length.


Pssm-ID: 434477  Cd Length: 296  Bit Score: 271.66  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510911   1 MAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHY-EVIPPLTSPGQPGDMNCTTQRINY 79
Cdd:pfam15122  24 MAVAVFLAYQTITDFREKLKHPVMSVSYKEVDSYDAPGIALYPGKAQLLSCKHHYhDHIPPLVDPGQPGEIDCVTEEINY 103

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510911  80 TDPFSNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQ 135
Cdd:pfam15122 104 TDPFTNQTEKHALVVRGPSDVRKRELVFLQFSLNETEEDFSAISYLLFSSFQEFLD 159
 
Name Accession Description Interval E-value
TMEM206 pfam15122
TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has ...
 1-135 1.88e-93

TMEM206 protein family; The function of this family of transmembrane proteins, TMEM206, has not, as yet, been determined. Members of this family are remain uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are approximately 350 amino acids in length.


Pssm-ID: 434477  Cd Length: 296  Bit Score: 271.66  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510911   1 MAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHY-EVIPPLTSPGQPGDMNCTTQRINY 79
Cdd:pfam15122  24 MAVAVFLAYQTITDFREKLKHPVMSVSYKEVDSYDAPGIALYPGKAQLLSCKHHYhDHIPPLVDPGQPGEIDCVTEEINY 103

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510911  80 TDPFSNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQ 135
Cdd:pfam15122 104 TDPFTNQTEKHALVVRGPSDVRKRELVFLQFSLNETEEDFSAISYLLFSSFQEFLD 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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